TitleAbstractYear(sorted ascending)
intrauterine and intrafetal inoculations with equine abortion virus in pregnant mares. 195313010086
cultivation of equine abortion virus in fetal horse tissue in vitro. 195313016787
adaptation of the equine abortion virus to suckling syrian hamsters. 195313094935
cultivation of the equine influenza virus in suckling syrian hamsters. its similarity to the equine abortion virus. 195413127395
thermal, hematological, and serological responses of weanling horses following inoculation with equine abortion virus: its similarity to equine influenza. 195413150758
the cultivation of equine abortion virus in cat tissue in vitro. 195413207311
susceptibility in vitro of adult horse tissue to equine abortion virus; previously undescribed lesions. 195513268617
propagation of equine abortion virus in the chick embryo. 195513273388
further observations of the in vitro susceptibility of adult horse tissue to equine abortion virus. 195613277324
propagation of equine abortion virus in syrian hamsters. 195613277325
propagation of equine abortion virus in the embryonated chicken egg. 195613277328
serological differentiation of the equine abortion virus from the human and swine influenza, mumps, and newcastle disease viruses. 195613302650
agglutination of horse erythrocytes by tissue extracts from hamsters infected with equine abortion virus. 195613302651
studies on hepatitis in hamsters infected with equine abortion virus. i. sequential development of inclusions and the growth cycle. 195713444458
adaptation of equine abortion virus to hela cells. 195713453487
studies on hepatitis in hamsters infected with equine abortion virus. ii. changes in protein, nucleic acid, and weight of isolated hepatic nuclei. 195713458334
electron microscopy of equine abortion virus. 195813591329
changes in protein and nucleic acid content on hela cells infected with equine abortion virus. 195813614503
isolation of equine abortion virus from natural cases of equine abortion in horse kidney cell culture. 195914446011
a preliminary survey for equine abortion virus infection by complement fixation test in hokkaido, japan. 195914404961
histopathological study of aborted fetuses naturally infected with equine abortion virus with some epidemiological findings. 195914404962
quantitation and morphology of equine abortion virus in hamsters. 196014445594
studies on hepatitis in hamsters infected with equine abortion virus. iii. nuclear protein changes. a histochemical study. 196013704424
composition of rna and dna of citric acid-isolated liver nuclei from hamsters infected with equine abortion virus (eav). 196013827336
electron microscopy of equine abortion virus. 196113774844
labelling of liver nuclei with tritiated thymidine in hamsters infected with equine abortion virus. 196113704423
adaptation of equine abortion virus to earle's l cells in serum-free medium with plaque formation. 196214490220
correlated autoradiographic and biochemical study of dna labeling in equine abortion virus hepatitis. 196213897734
[in vitro sensitivity of different types of cells to infection with infectious equine abortion virus (dimock)]. 196214008371
an electron microscopic study of equine abortion virus infection in hamster liver. 196314013743
the nucleic acid content of equine abortion virus. 196314025123
degradation of deoxyribonucleic acid and alteration nucleic acid metabolism in suspension cultures of l-m cells infected with equine abortion virus.randall, charles c. (university of mississippi school of medicine, jackson) and barbara m. walker. degradation of deoxyribonucleic acid and alteration of nucleic acid metabolism in suspension cultures of l-m cells infected with equine abortion virus. j. bacteriol. 86:138-146. 1963.-metabolic alterations in log-phase suspension cultures infected with equine abortion virus (eav) were determined in l-m cells simultaneously labeled or prelabeled with h(3)- or c(14)-thymidine. although infection prod ...196314051805
replication of a deoxyribonucleic acid virus in thymine-deficient mammalian cells.gentry, glenn a. (university of mississippi school of medicine, jackson), lucy a. lawson, and charles c. randall. replication of a deoxyribonucleic acid virus in thymine-deficient mammalian cells. j. bacteriol. 88:1324-1328. 1964.-equine abortion virus (eav), a deoxyribonucleic acid (dna) virus, causes the degradation of host cell dna to acid-soluble components in the l-m cell. it was hypothesized that inhibitors of dna synthesis such as 5-fluorodeoxyuridine (fudr) and amethopterin, which act by ...196414234788
[first isolation of equine abortion virus from aborted fetus in western germany]. 19644305858
[electron optical demonstration of the equine abortion virus with the aid of the negative contrast procedure]. 19645890648
[characterization of an equine abortion virus from poland and comparison with known equine rhinopneumonitis virus strains]. 19655894190
some physicochemical characteristics of equine abortion virus nucleic acid. 196514319712
biological and morphological aspects of the growth of equine abortion virus.darlington, r. w. (st. jude children's research hospital, memphis, tenn.), and c. james. biological and morphological aspects of the growth of equine abortion virus. j. bacteriol. 92:250-257. 1966.-the growth of equine abortion virus (eav) was studied by bioassay and electron microscopy in l-cell monolayer and suspension cultures, and in hela and bhk 21/13 cell monolayers. results of virus assay (plaque-forming units) indicated that production of cell-associated virus (cav) began at 6 to 9 hr af ...19665941279
hepatitis due to equine abortion virus. comparison between the liver histology in human, canine, duckling, and equine viral hepatitis.five livers of equine fetuses, aborted due to the action of equine abortion virus, five livers from men, two of whom died of epidemic hepatitis and three obtained by needle biopsies, 5 livers of dogs with infectious canine hepatitis and 7 livers of ducklings that had hepatitis, were studied histopathologically. the foals' livers were studied by several staining methods and the others by h. e. only. the results indicate that the lesions are quite similar in the four species with the appearance of ...19664225286
kinetics of viral deoxyribonucleic acid, protein, and infectious particle production and alterations in host macromolecular syntheses in equine abortion (herpes) virus-infected cells.infection of exponential-phase suspension cultures of mouse fibroblast cells (l-m) with equine abortion virus (eav) resulted in inhibition of cell growth and marked alterations in host metabolic processes. the synthesis of deoxyribonucleic acid (dna) and ribonucleic acid was inhibited within 4 hr after infection and was suppressed by more than 90% by the time of maximal virus replication (14 to 18 hr). the overall rate of protein synthesis, however, was similar in uninfected and virus-producing ...19684302745
[research into the inactivation effect of surface-active substances on the rhinopneumonitis virus in horses (equine abortion virus)]. 19685683868
mycoplasmal deoxyribonuclease activity in virus-infected l-cell cultures.cell-free extracts of mycoplasma hominis and medium from 72-hr broth cultures had deoxyribonuclease activity like that of deoxyribonuclease i. mg(++) stimulated activity, and the ph optimum was between 8.0 and 9.0. double-stranded or heatdenatured deoxyribonucleic acid (dna) served as a substrate, and oligonucleotides were produced. cell-free extracts of l cells infected with m. hominis or m. hominis plus equine abortion virus (equine herpes virus, eav) had greatly increased activity over that o ...19695782042
comparison of four horse herpesviruses.four equine herpesviruses (equine abortion virus, equine herpesvirus types 2 and 3, and equine cytomegalovirus) were compared. the equine abortion virus did not cross-neutralize with any of the other viruses, but the other three did show varying degrees of cross-neutralization among themselves. equine abortion virus grew more quickly in tissue cultures than did the others, and attained higher titers of infectivity in the culture fluid; it also formed plaques in a wider range of tissue culture sp ...19694982831
on immunity to disease caused by equine herpesvirus 1. 19694307796
[on antigen relationship between herpes simplex virus, herpes virus platyrrhinae (marmoset herpesvirus) and equine abortion virus]. 19694318305
deoxyribonucleic acid synthesis in synchronized mammalian kb cells infected with herpes simplex virus.we examined the patterns of host cell and virus deoxyribonucleic acid (dna) synthesis in synchronized cultures of kb cells infected at different stages of the cell cycle with herpes simplex virus (hsv). we found that the initiation of hsv dna synthesis, we well as the production of new infectious virus, is independent of the s, g1, and g2 phases of the mitotic cycle of the host cell. this is in contrast to data previously found with equine abortion virus. because hsv replicates independently of ...19714327586
paralysis of horses associated with equine herpesvirus 1 infection. 19714328999
evidence for a relationship between equine abortion (herpes) virus deoxyribonucleic acid synthesis and the s phase of the kb cell mitotic cycle.autoradiographic analyses of deoxyribonucleic acid (dna) synthesis in randomly growing kb cell cultures infected with equine abortion virus (eav) suggested that viral dna synthesis was initiated only at times that coincided with the entry of noninfected control cells into the s phase of the cell cycle. synchronized cultures of kb cells were infected at different stages of the cell cycle, and rates of synthesis of cellular and viral dna were measured. when cells were infected at different times w ...19714254680
nucleic acid and protein synthesis in kb cells infected with equine abortion virus (equine herpesvirus type 1). 19715099956
equine herpesvirus type 1: the l- character in two of forty-three field isolates. brief report. 19725063121
effect of antiviral agents in equine abortion virus-infected hamsters.equine abortion virus, a member of the herpesvirus group, produces a lethal infection in hamsters. with this system, the protective effect of certain inhibitors of deoxyribonucleic acid viruses, inducers of interferon and exogenous interferon, was evaluated. of the various agents studied, 9-beta-d-arabinofuranosyladenine markedly suppressed mortality, and 5-iodo-2'-deoxyuridine, distamycin a, and n-ethylisatin beta-thiosemicarbazone were inactive. of the inducers tested, statolon, ultraviolet-ir ...19724376907
[virological studies of the central nervous system of horse fetuses and findings in mares suffering from central nervous system disease following abortion caused by equine herpesvirus 1]. 19724334255
protein kinase activity in equine herpesvirus.a protein kinase which is intimately associated with equine herpesvirus (equine abortion virus) was found by using adenosine triphosphate-gamma-(32)p as a phosphate donor and virus protein as an acceptor. consistent demonstration of the activity requires prior removal of phosphohydrolase. the kinase activity requires mg(2+), is not stimulated by cyclic adenosine monophosphate, but is enhanced by added protamine or arginine-rich histone. the labeled product is resistant to ribonuclease, deoxyribo ...19724335515
[effect of air humidity on the tenacity of equine herpesvirus 1 (rhinopneumonitis virus) using different carriers]. 19734692643
equine herpesviruses: antigenic relationships and deoxyribonucleic acid densities.equine herpesviruses with a deoxyribonucleic acid density of 1.716 to 1.717 g/cm(3) were compared with one another by the plaque-reduction test and by the rate of development of cytopathic effect as indicated by plaque size in rabbit kidney cultures. of the 19 isolates studied, the 9 which had already been tentatively labeled equine abortion viruses were serologically similar to one another; each of them grew more quickly than did any of the other 10 isolates although the mean plaque sizes forme ...19734742974
equine abortion (herpes) virus: evaluation of markers in a field vaccination trial.twelve mares were vaccinated with attenuated equine abortion virus (eav) strain rac-h. two nonvaccinated mares served as controls. in at least three mares the vaccination appeared to coincide with a natural infection. this was indicated by characterization of the eav isolated from nasal secretions of six vaccinated mares, a nonvaccinated control, and also from the lung, spleen, and liver of a fetus aborted by a vaccinated mare. the relative sensitivity of the isolated eav to dithiothreitol was u ...19734796167
equine herpesvirus 1: biological and biophysical comparison of two viruses from different clinical entities. 19744376548
morphological components of herpesvirus. i. intercapsomeric fibrils and the geometry of the capsid.highly purified equine herpesvirus type 1 (ehv-1) and herpes simplex virus type 1 (hsv-1) were observed by electron microscopy in various stages of disintegration. under the conditions used, envelopes of virions usually were fragmented, and virus capsids collapsed in situ into flattened sheets of capsomeres. a matrix of intercapsomeric fibrils was observed. evidence suggesting that the capsid hexamer has threefold structural symmetry is presented.19744376809
iododeoxyuridine and herpesviral encephalitis: lack of inhibitory action against low-grade viral replication.equine herpesvirus 1 replicated in the brains of 2-week-old mice but did not produce fatal encephalitis; it thus simulated the majority of cases of herpes simplex encephalitis in man. this replication was not inhibited by iododeoxyuridine, although in tissue cultures the equine and human viruses were equally susceptible. the continued use of iododeoxyuridine for human encephalitis should be seriously questioned.197415825425
herpesvirus-induced availability of host dna to exogenous endonuclease.deoxyribonuclease i penetrates herpesvirus-infected l cells and degrades host dna without interfering with viral multiplication. the dna of uninfected control monolayers of l cells, disrupted by scraping, is similarly attacked. in contrast, undisturbed l cells are not affected. this suggests that altered cell membrane permeability allows the nuclease to enter the cell, thereby permitting access of exogenous deoxyribonuclease to cellular dna.1975241244
immunity and the level of neutralization antibodies in foals and mares vaccinated with a modified live-virus rhinopneumonitis vaccine.foals (farms 1 and 2) and mares (farms 1 and 3) vaccinated with a commercially available rhinopneumonitis vaccine were tested for the level of antibodies and for protection against the natural infection. the serum-neutralization (sn) antibody titers against equine herpesvirus type 1 were 1:8 or less in the majority of foals and 1:16 or higher in about 10%. the level of the nasal secretory antibody in the foals (farm 2) was less than 1:4. the vaccinated foals did not show any apparent respiratory ...1975164808
specific immunity and nonspecific resistance to infection: listeria, protozoa, and viruses in mice and hamsters,.specific immunity developed by mice against protozoan (toxoplasma gondii and besnoitia jellisoni) and bacterial (listeria monocytogenes) infections was compared with nonspecific protection conferred by prior infections. the results indicated that homologous immunity protected mice from more than 10-5 ld50 of t. gondii or b. jellisoni, but from only 10-2 ld50 of l. monocytogenes. heterospecific protection among these organisms was for 10-0.4 minus 10-1.2 ld50. in studies in hamsters specific immu ...1975165241
isolation of equine herpesvirus type 1 from a horse with an acute paralytic disease.a standardbred mare became paralyzed shortly after showing signs of an upper respiratory infection. the mare was euthanized and equine herpesvirus type 1 was isolated from the brain and spinal cord.1975166741
the prevalence of equid herpes virus 2 infections. 1975167501
mitochondrial and herpesvirus-specific deoxypyrimidine characterize and compare the thymidine (tdr) and deoxycytidine (cdr) kinase isozymes of uninfected and herpesvirus-infected cells: (i) the subcellular distribution of the isozymes has been studied; (ii) a specific assay for cdr kinase has been devised; (iii) the tdr kinase isozymes have been partially purified; and (iv) the purified enzymes have been analyzed by disc polyacrylamide gel electrophoresis, isoelectric focusing, and glycerol gradient centrifugation and by substrate competition and ...1975169387
[equine rhinopneumonitis virus infection in horses (author's transl)]. 1975170706
replication of equine herpesvirus type i: resistance to hydroxyurea. 1975170739
virus-induced abortion. studies of equine herpesvirus 1 (abortion virus) in hamsters.a hamster-adapted strain of equine herpesvirus-1 (equine abortion virus) caused severe hepatic degeneration in both pregnant and nonpregnant hamsters and, in addition, regularly induced abortion in pregnant hamsters inoculated at midgestation. in nonpregnant hamsters, the only consistently affected organ was the liver despite a prolonged viremia. newborn animals usually died 1 to 2 days after inoculation; adults died 5 to 9 days after inoculation. in pregnant hamsters, the virus had a tropism fo ...1975171478
efficacy of 9-beta-d-arabinofuranosylhypoxanthine 5'-monophosphate in therapy of equine abortion virus-induced hepatitis in hamsters.equine abortion virus (eav)-induced hepatitis in hamsters presents an interesting animal model for the evaluation of drugs possessing anti-deoxyribonucleic acid virus activity. these experiments demonstrate that 9-beta-d-arabinofuranosylhypoxanthine 5'-monophosphate (ara-hxmp), a new synthetic, water-soluble, antiviral agent, effectively controls this disease in hamsters with a therapeutic index of approximately 60. ara-hxmp prevented hepatitis-associated deaths in hamsters, reduced the titer of ...1975172009
equine herpesvirus-induced alterations in nuclear rna and dna polymerase activities. 1975173079
transcription of equine herpesvirus type 1: evidence for classes of transcripts differing in abundance. 1975173082
experimental studies on equine herpesvirus type 1 infections.the ehv-1 viruses of fetal origin grew better and had a wider tissue culture host range than those isolated from horses with respiratory diseases. comparisons of a fetal isolate (f/304) and a respiratory disease isolate (r/nm-3) in partly immune horses showed that the f/304 virus infected horses more readily, grew better in the nasopharynx, was more likely to cause abortion, and was excreted to a greater extent into the environment.1975173849
characterization of three species of nucleocapsids of equine herpesvirus type-1 (ehv-1). 19751167720
equine herpesvirus in vivo: cyclic production of a dna density variant with repetitive sequences. 1976176793
[developmental stages of herpesvirus-equi-1 in nasal mucosa cells]. 1976176846
effects of crude extracts of various plants on infectious bovine rhinotracheitis virus-plaque production.extracts of 28 plants were tested without demonstable antiviral activity in an agar-overlay plaque-reduction antiviral assay system, using infectious bovine rhinotracheitis virus and bovine endocardial cell cultures. ethanolic extract of narcissus tazetta l bulb elicited antiviral activity by inhibition of viral plaque formation. antiviral activity was demonstrated against infectious bovine rhinotracheitis and equine rhinopneumonitis viruses. narcissus tazetta l bulb did not directly inactivate ...1976176907
letter: efficacy of modified live-virus equine rhinopneumonitis vaccine. 1976176909
capsomeres of herpesvirus-equi-l in thin sections. 1976176974
serological detection of equid herpesvirus 1 infections of the respiratory investigation was made of 3 serological tests (virus neutralization, complement fixation and indirect immunofluorescence), which are applicable to epidemiological studies of infections by equid herpesvirus 1 (ehv-1). sera from gnotobiotic foals inoculated intranasally with various strains of ehv-1 were unable in some cases to neutralize heterologous strains and these results were not consistent with the existence of clearly-defined subtypes of ehv-1, as previously proposed. the cross-reaction ...1976177281
purification of equine herpesvirus type 1.a method for the purification of enveloped infectious equine herpesvirus type 1 (ehv-1) is presented. virus from cell culture fluids harvested at 48 h post infection was concentrated by sedimentation and partially purified by differential precipitation with ammonium sulphate. the final steps of purification consisted of two cycles of flotation of virus in pre-formed cscl density gradients. yields of infectious virus were about 30% (18 to 44%) of that present in starting material. as judged by el ...1976177732
viral respiratory infections. 1976177853
[equine rhinopneumonitis virus infection in horses. ii (author's transl)]. 1976178066
abortion associated with mixed leptospira/equid herpesvirus 1 infection. 1976178087
practical aspects of equine virus abortion in the united kingdom.the current knowledge of the clinical signs, epidemiology and pathogenesis of abortion due to the equid herpesvirus (ehv 1) is reviewed. the relationship between the respiratory and abortigenic forms of the disease is discussed as well as the low incidence of virus abortion in the uk compared to some other parts of the world. some practical aspects of the disease as they affect stud management are considered including methods of diagnosis, prophylaxis and the necessary action to be taken to prev ...1976178088
[case of rhinopneumonia in horses in kirghizia]. 1976178089
letter: equine virus abortion. 1976179184
immunity to equine herpesvirus type 1 (rhinopneumonitis): in vitro lymphocyte response.twenty-two ponies were examined for serum-neutralizing (sn) antibody to equine herpesvirus type 1 and for in vitro lymphocyte transformation in the presence of viral antigen. six ponies had undetectable levels of neutralizing antibody (titer less than 1:2) and had lymphocytes which did not respond in culture with viral antigen (stimulation index less than 2.0). four ponies which had sn antibody to equine herpesvirus type 1 did not manifest lymphocyte transformation in vitro. the 12 remaining ser ...1976179451
meningoencephalomyelitis in horses associated with equine herpesvirus 1 infection.during an outbreak of abortion caused by equine herpesvirus 1, a neurologic disease characterized clinically by dullness and ataxia occurred in several mares. equine herpesvirus 1 was isolated from brain and lung of two severely affected mares. histologically, both mares had disseminated meningoencephalomyelitis characterized by necrotizing arteritis, focal malacia in grey and white matter of brain and spinal cord, and accumulation of lymphocytes and neutrophils in paravertebral ganglia. eosinop ...1976180650
disseminated necrotizing myeloencephalitis: a herpes-associated neurological disease of horses.equine viral rhinopneumonitis type i virus was isolated from spinal cord and brain of a paraparetic horse with disseminated necrotizing myeloencephalitis. necrotic arteriolitis,nonsuppurative necrotizing myeloencephalitis and gasserian ganglioneuritis were present. on record were 12 more cases of horses with similar lesions. the horses had been ataxic or paretic for up to several weeks. a field survey indicated that 14 of 24 horses with acute myelitic signs developed them after recent exposure t ...1976180652
serological study of an outbreak of paresis due to equid herpesvirus 1 (ehv-1).six cases of paresis occurred in a swedish stud with 48 mares and a stallion. complement-fixation tests revealed a recent infection with ehv-1 in most horses of the stud. serumneutralisation tests showed rapid antibody-titre increases during the course of the disease. this type of antibody response was interpreted as induced by reinfection or, possibly, recurrent infection. two diseased mares were sacrificed. no virus could be isolated from their central nervous system (cns), liver or spleen, bu ...1976181891
letter: isolation and characterisation of equine herpes virus type 1. 1976183339
equine herpesviruses. 6. sequential infection of horses with types 2, 3 and 1.the immunological and virological status of 3 foals in respect of equine herpesviruses (ehv) was established and the foals were sequentially infected with ehv2, ehv3 and ehv1. following experimental infection with ehv2, no clinical signs of disease were observed in any foal. the inoculation of ehv3 into the genital tract resulted in lesions of the mucous membrane and perineal skin that were considered typical of equine coital exanthema. following intransal inoculation of ehv3 extensive ulceratio ...1976183644
[infection of hela cells by herpes virus of horses type 1 in different temperature and dose of the virus (author's transl)]. 1976183896
[persistent infection of stable cell cultures by herpes virus of horses type 1 (author's transl)]. 1976183897
[combined vaccination plan against influenza, equine rhinopneumonitis and tetanus for thoroughbred horses]. 1976183944
failure to demonstrate equine rhinopneumonitis virus as a cause of abortion in mares in new zealand. 1976190568
equine viral encephalitis.the most important neurotropic viral infections of the horse are the arthropod-borne encephalitides. these include venezuelan encephalitis (ve), eastern encephalitis (ee) and western encephalitis (we), which are found in the americas, and japanese b encephalitis which occurs in the far east. all the viruses cause encephalitis in man. between 1969 and 1972 an epidemic of ve occurred in central america. in 1971 the disease was reported in texas, where it was brought under control by the vaccinatio ...19764301
biochemical studies of the maturation of herpesvirus nucleocapsid species.three distinct species of nucleocapsids of equine herpesvirus type-1, designated as either light (l), intermediate (i), or heavy (h) on the basis of their densities in renografin-76 density gradients (perdue et al. 1975), were characterized with respect to their amino acid content, dna content, and role in the maturation process. preparations of l and i nucleocapsids, shown previously to lack a densely staining core within the capsid, exhibited virtually identical amino acid compositions. prepar ...197618625460
herpesvirus transcription: altered regulation induced by fudr. 1977190769
infectious causes of equine respiratory disease on ontario standardbred racetracks.upper respiratory disease has been a serious problem in standardbred horses on racetracks in ontario, with outbreaks occurring once or twice annually in late winter and early spring seasons. to determine the causes of these epidemics, a 3-year investigation was carried out in which nasal swabs and serum samples were obtained at intervals from apparently healthy horses and from horses suffering from upper respiratory disease. the nasal swabs were used to isolate bacteria and viruses. the serum sa ...1977192757
Displaying items 1 - 100 of 1327