TitleAbstractYear(sorted descending)
infection with herpes-simplex viruses 1 and 2. ii.herpes-simplex virus 1 (hsv1) and 2 can cause recurrent infection in man and in nonhuman species localized on a specific area of the body, such as face, cornea, or genitals. the origin of the virus responsible for a recurrent infection is not usually apparent. some possible sources of virus can be exogenous infection, endogenous infection from another site of the body, chronic, continuous viral multiplication around the site of involvement, and persistence of the virus at the site of the recur ...19734353782
[relationship between herpes simplex virus type 2 and carcinoma of the uterine cervix]. 19734354419
oncogenic transformation of hamster embryo cells after exposure to inactivated herpes simplex virus type 1.the in vitro transformation of hamster embryo fibroblasts by herpes simplex virus type 1 (hsv-1) after exposure of the virus to uv irradiation is described. cell transformation was induced by 2 out of 12 strains of hsv-1 that were tested for transforming potential. cells transformed by the kos strain of hsv-1 were not oncogenic when injected into newborn syrian hamsters. however, cells transformed by hsv-1 strain 14-012 induced tumors in 47% of the newborn hamsters injected. hsv-specific antigen ...19734355928
herpes simplex meningitis: isolation of herpes simplex virus type 2 from cerebrospinal fluid. 19734356148
infection, haemorrhage and death of chick embryos after inoculation of herpes simplex virus type 2 on to the chorioallantoic membrane. 19734357372
genetic relatedness of type 1 and type 2 herpes simplex viruses.the extent of homology between herpes simplex virus(1) and(2) (hsv-1 and hsv-2) deoxyribonucleic acid (dna) was measured in two ways: (i) by determination of the relative rate of hybridization of labeled hsv-1 and hsv-2 dna to excess unlabeled hsv-1 or hsv-2 dna immobilized on filters and (ii) by determination of the rate of hybridization of labeled hsv-1 and hsv-2 dna to excess unlabeled hsv-1 or hsv-2 dna in solution. approximately 40% of hsv-1 and hsv-2 dna is homologous at hybridization temp ...19724337161
mechanism of the restricted growth of herpes simplex virus type 2 in a hamster cell line. 19724342820
proteins specified by herpes simplex virus. 8. characterization and composition of multiple capsid forms of subtypes 1 and 2.two classes of herpesvirus capsids, designated a and b, were isolated from the nuclei of human cells infected with herpes simplex virus (hsv). a and b capsids share in common four structural proteins, i.e., no. 5, 19, 23, and 24. b capsids contain 7.7 to 9.7 times more deoxyribonucleic acid than a capsids; moreover, they contain proteins no. 21 and 22a in addition. all of the proteins contained in the capsid except no. 22a are present in the enveloped nucleocapsids (virions) in approximately the ...19724344252
[herpes simplex virus type 2: its distribution and relationship to cervical carcinoma]. 19724344976
ultrastructural characterization of hamster cells transformed following exposure to ultraviolet-irradiated herpes simplex virus type 2. 19724345407
absence of leukosis virus markers in hamster cells transformed by herpes simplex virus type 2.hamster cells which transformed after exposure to herpes simplex virus type 2 previously irradiated with ultraviolet light were tested for the presence of hamster leukosis viruses or their virus-specific antigens. three techniques that were used did not detect the presence of either hamster c-type particles or antigens commonly associated with such structures. the implication of these findings to current concepts of virus oncology is discussed.19724113887
susceptibility of herpesviruses to cytosine arabinoside: standardization of susceptibility test procedure and relative resistance of herpes simplex type 2 strains.susceptibility testing of herpes simplex type 1 (hsv-1) and type 2 (hsv-2) viruses to cytosine arabinoside (ara-c) has been standardized under conditions of optimal reproducibility, susceptibility, and simplicity. standard conditions were defined as virus inoculum of 10(1.5) to 10(2.5) tcid(50), wi-38 strain of lung fibroblasts, 2-day incubation, and observation of virus cytopathic effect after staining by the may-greenwald-giemsa method. the variability of minimum inhibitory concentration (mic) ...19724364937
differential effect of 7,12-dimethylbenz(a)anthracene on infectivity of herpes simplex virus type 2. 19714322268
oncogenic transformation of hamster cells after exposure to herpes simplex virus type 2. 19714329350
size, composition, and structure of the deoxyribonucleic acid of herpes simplex virus subtypes 1 and 2.studies of the size, composition, and structure of the deoxyribonucleic acid (dna) of the f and g prototypes of herpes simplex virus (hsv) subtypes 1 and 2 (hsv-1 and hsv-2) showed the following. (i) as previously reported by good-heart et al. hsv-1 and hsv-2 dna have a buoyant density of 1.726 and 1.728 g/cm(3), corresponding to 67 and 69 guanine +/- cytosine moles per cent, respectively. the difference in guanine plus cytosine content of the dna species was confirmed by the finding of a 1 c di ...19714329966
temperature-sensitive mutants of herpes simplex virus type 2. 19714333719
synergistic effect of herpes simplex virus and cytosine arabinoside on human chromosomes.the combined treatment of cultures of human embryonic lung cells with herpes simplex virus type 2 and cytosine arabinoside produced a significantly increased number of cells containing multiple chromatid and chromosome breaks. the incidence of such cells was found to be approximately two and one half times greater than the additive effects of virus and cytosine arabinoside induced separately and is therefore synergistic.19714104257
properties of hamster embryo fibroblasts transformed in vitro after exposure to ultraviolet-irradiated herpes simplex virus type in vitro method which led to the transformation of hamster embryo fibroblasts after exposure to herpes simplex virus type 2 (hsv-2) inactivated with ultraviolet irradiation is described. the transformed cells (333-8-9) produced tumors when inoculated into newborn syrian hamsters but not when injected into weanling syrian hamsters of the same lsh inbred strain. however, after one in vivo passage, the 333-8-9 cells became highly oncogenic in weanling hamsters. no infectious virus was recovered ...19714108570
[genetic markers of herpes simplex virus. 2. study of genetic markers of the us strain of herpes simplex virus of the 3d antigenic group]. 19704319413
chronic infections by herpes simplex viruses and by the horse and cat herpesviruses.rabbit eyes experimentally infected with either type 1 or type 2 herpes simplex viruses occasionally released virus spontaneously. injection of adrenalin was not highly effective for stimulating virus release but did seem to have a slight and erratic activating capacity. no spontaneous virus release were detected from the eyes of six cats infected with cat herpesvirus, but, when adrenalin was administered, an episode of virus release did ensue in one animal. rabbit spinal cords could be chronica ...197016557741
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