Publications

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antiviral action of mouse interferon in heterologous cells.buckler, charles e. (national institute of allergy and infectious diseases, bethesda, md.), and samuel baron. antiviral action of mouse interferon in heterologous cells. j. bacteriol. 91:231-235. 1966.-the antiviral action of mouse interferon in cell cultures of mouse, hamster, rat, chicken, and monkey origin was investigated. using a vesicular stomatitis virus (vsv) plaque reduction test, we found that mouse serum interferon, assayed on closely related rat or hamster cells, exerted 5% of its ho ...19664285534
inhibition of sindbis virus plaque formation by extracts of escherichia coli.vilcek, jan (new york university school of medicine, new york, n.y.), and john h. freer. inhibition of sindbis virus plaque formation by extracts of escherichia coli. j. bacteriol. 92:1716-1722. 1966.-extracts prepared from washed cells of escherichia coli b by sonic treatment and subsequent filtration through a 0.45-mu membrane filter significantly inhibited plaque formation with sindbis virus in cultures or primary chick embryo cells up to a dilution of 1:20,000. the inhibitor acted on the cel ...19664289359
the virus inactivating capacity of sea water. 19664289436
inhibition of interferon production by a halogenated pyrimidine derivative: 5-fluoro-2'-deoxyuridine. 19664289890
non-heritable interferon resistance in a fraction of virus populations. 19664286948
yaba tumor poxvirus synthesis in vitro. i. cytopathological, histochemical, and immunofluorescent studies.yohn, david s. (roswell park memorial institute, buffalo, n.y.), victoria a. haendiges, and james t. grace, jr. yaba tumor poxvirus synthesis in vitro. i. cytopathological, histochemical, and immunofluorescent studies. j. bacteriol. 91:1977-1985. 1966.-yaba tumor poxvirus synthesis in bsc-1 cell culture was followed sequentially with light microscopy, immunofluorescent microscopy, and various histochemical stains. the first evidence of infection was detected at 24 hr when nucleoli became hypertr ...19664287080
biological activities of 3-isoadenosine. 19664289989
viral inhibitory activity of polyvinylpyrrolidone. 19664290611
production of interferon by human leukocytes in vitro. 19664290664
some nuclear-substituted derivatives of alpha-methyldopa. 19664291024
[the effect of the virus inhibiting factor on oxidative phosphorylation]. 19664291053
in vitro studies on the antiviral activity of 1, 3-bis(2-chloroethyl)-1-nitrosourea.chemotherapy experiments carried out in vitro demonstrated that 1,3-bis(2-chloroethyl)-1-nitrosourea (bcnu) was active against lymphocytic choriomeningitis virus and had an equivocal antiviral effect on semliki forest, herpes simplex, and vaccinia viruses. no antiviral effect was observed with bcnu against western equine encephalomyelitis, polio, and parainfluenza (ha-1) viruses. activity of the drug was determined by inhibition of viral-induced cytopathogenic effect in kb or chick embryo cells ...19664291237
[antiviral activity in vitro of 5-hydroxytryptophan]. 19664293045
[the effect of virus infections on the course of cell division]. 19664293583
[induction of the "stripping enzyme" in different viruses of the smallpox-vaccinia group]. 19664297720
the development of skin resistance and hypersensitivity following inactivated vaccinia virus vaccines in rabbits. 19665219019
suppression of vaccinia virus reproduction by specific action on the cell. 19665223519
concerning the mechanism of action of interferon. 19665229977
[production of the virus inhibiting factor by peritoneal phagocytes of the uninoculated rabbit]. 19665298296
electron microscopic studies on the effect of virus inhibiting factor on virus multiplication. 19665298410
electron microscopic studies of human glomerulonephritis with ferritin-conjugated antibody. localization of antigen-antibody complexes in glomerular structures of patients with acute glomerulonephritis.1. kidney biopsies from 4 cases of severe acute glomerulonephritis were obtained 11 to 25 days after the onset of clinical manifestations of the disease. these tissues were treated with ferritin-conjugated antibodies to 7s gamma-globulin, beta(1c), and type 12 streptococcal products. adjacent pieces of the biopsied material were treated with control ferritin-labeled antisera or with ferritin alone. as further controls, normal renal tissue and renal tissue from patients with other kidney diseases ...19665324224
the effect of hydroxyurea on virus development. ii. vaccinia virus. 19665328227
studies on the nature of marchal bodies (a-type inclusion) during ectromelia virus infection. 19665329147
[observation, by means of immunofluorescence, of the appearance and evolution of vaccinal antigen in cell cultures]. 19665336603
[studies on susceptíbility of ocular tissues to cowpox virus]. 19665338556
[chromosome aberrations following latent infection of a cloned l-cell stock with vaccinia viruses]. 19664957470
antiviral compounds. 8. aminoacethydrazones of aromatic alpha-ketoaldehydes. 19664961227
[on the possibility of oral immunization of experimental animals with vaccinia virus. i. immunologic shifts in the vaccinated animals]. 19664978581
[synthesis of proteins and nucleic components of vaccinia virus]. 19664887655
temporal relationship of interferon production and resistance to experimentally induced virus infection. 19665908851
[role of fever in vaccinal pneumonia in rabbits. comparative study of in vivo virus development in febrile and apyretic animals]. 19665909616
effect of "cephaloridine" on vaccinia virus in vitro. 19665912440
susceptibility of primary and continuous cell lines to vaccinia virus. 19665919649
the effect of crude preparations of vaccinia on mitosis and dna synthesis of kb cells.a morphologic study has been made on kb cells infected with various doses of vaccinia as to dna synthesis and mitosis. determination of mitotic indices revealed that the mitotic cell pool depended on the proportion of infected cells and the time after infection. by cytologic examination neither mitotic lesions were found nor an accumulation of mitotic cells at any one stage of mitosis was demonstrated. radioautographs of infected cultures have shown that the frequency of cells labeled over nucle ...19665919690
electron microscopic observations on the nature of vaccinia virus particle aggregation. 19665921311
effect on influenza virus of a modified francis inhibitor and its acetone-soluble fraction. i. studies in roller drum, and in de-embryonated eggs. 19665922215
micro-electrophoresis of cowpox and vaccinia viruses in molar sucrose. 19665922291
multiplicity reactivation and radiation survival of aggregated vaccinia virus. calculation of plaque titer based on mr and particle aggregation seen in the electron microscope. 19665922451
soluble antigens of vaccinia-infected mammalian cells. i. separation of virus-induced soluble antigens into two classes on the basis of physical characteristics.cohen, gary h. (university of pennsylvania, philadelphia), and wesley c. wilcox. soluble antigens of vaccinia-infected mammalian cells. i. separation of virus-induced soluble antigens into two classes on the basis of physical characteristics. j. bacteriol. 92:676-686. 1966-infection of mammalian cells with members of the poxvirus group elicits production of a number of virus-induced, soluble antigens. immunoelectrophoresis and immunodiffusion techniques employing soluble antigen preparations obt ...19665922541
multiplicity reactivation of vaccinia virus in the cells of the chorioallantoic membrane. 19665924408
vaccinia virus in organ cultures of an adult rabbit's skin. 19665928600
rabbitpox virus. anomalous plaque production. 19665928800
electron microscopic autoradiography of dna synthesis in cells infected with vaccinia virus. 19665929573
controlled degradation of vaccinia virions in vitro: an electron microscopic study. 19665930347
[chromosome aberrations in l-cells following vaccinia virus infection]. 19665941953
effect of vaccinia virus on malignant melanoma of hamsters. 19665943360
induction of cytoplasmic ribonucleic acid (rna) synthesis in vaccinia-infected lm cells during inhibition of protein synthesis. 19665949673
the vmk variant of a strain of poxvirus officinale. 3. further differentiation of the vmk strain. 19665950218
immunoelectrophoretic analysis of vaccinia virus. 19665950825
autointerference of rabies virus in chick embryo fibroblasts. 19665951071
studies on placentae and infants from women vaccinated for smallpox during pregnancy.sixty-five placentae from women who had been vaccinated while pregnant were examined for the presence of the inclusion bodies of vaccinia. also suspensions from 40 of the placentae were inoculated into the chorio-allantoic membrane of chick embryos in an attempt to culture any vaccinia virus present. both these studies gave negative results.the results of the pregnancies of these 65 women showed no increase in the incidence of abortion, stillbirth, or congenital abnormalities, over the unvaccina ...19665951719
quantitative studies on fabrics as disseminators of viruses. i. persistence of vaccinia virus on cotton and wool fabrics.the persistence of vaccinia virus on wool (blanket and gabardine) and cotton (sheeting, terry cloth, and knit jersey) fabrics was studied. the fabrics were exposed to the virus by three methods: direct contact, aerosol, and virus-containing dust having a high content of textile fibers. fabrics exposed to virus by each method were held in 35 and 78% relative humidities at 25 c. virus was recovered for up to 14 weeks from wool fabrics exposed to virus and held in the low humidity. in contrast, vir ...19665953019
role of plasma factors in the transformation of peripheral blood lymphocytes into lymphoblasts. 19665954573
inhibiting effect of increasing body-weight on the lethal response of dba-i mice to vaccinia virus infection. 19665954584
vaccinia virus hi-antibody blocked by a non-haemagglutinating extract of vaccinia infected cam. 19665954974
on the neoplastic transformation induced by vaccinia virus in primary cultures of mouse embryos. 19665961914
the reaction of vaccinia virus with deoxycholate. 19665965994
method for enchancement of electron microscopic visualization of embedded antigen by bridging osmium to uranium antibody with thiocarbohydrazide. 19665969756
cultivation and immunological studies of the pox group of viruses. i. propagation of vaccinia virus in hamster kidney cell culture. 19665969955
synthesis of dna and protein in cells infected with vaccinia virus. 19665971691
[pyodermia chancriformis]. 19665976210
simultaneous infection with foot and mouth disease and vaccinia virus. 19665977007
effect of concomitant treatment by cortisone and n-ethylisatin beta-thiosemicarbazone on neurovaccinia virus infected mice. 19665980557
the wet preservation of vaccinia virus. 19665982354
[a simple and rapid method for differentiation between vaccine (poxvirus officinale) and cow pox virus (poxvirus bovis)]. 19665984723
effect of n-ethylisatin beta-thiosemicarbazone and anticonvulsant drugs on tonic convulsions in neurovaccinia-infected mice. 19665985283
evaluation of antiviral compounds by suppression of tail lesions in vaccinia-infected mice. 19665985284
[investigation on the formation of serum antibodies after revaccination with vaccinia virus]. 19665990063
[the determination of the density of viruses in a cesium chloride-water gradient. comparative studies of vaccinia virus and ectromelia virus]. 19665991313
[a modified method of inoculation of chorioallantoic membranes for virus cultivation]. 19665992407
[effect of some inhibitors on the formation of the factor of nucleocapside deproteinization in vaccinia virus]. 19665994933
[on the demonstration of airborne viruses. experiments on the sedimentation of viruses in aerosols]. 19665995378
a simplified plaque technique for titration of pox virus and its antibodies in chick embryo cells. 19666006243
experiences with improvement of the neutralization reaction with vaccinia virus in chick fibroblast cultures. 19666006816
[effects of histone on the intracellular development of vaccinia virus]. 19666008708
[clinical and experimental studies on the passive transferability of vaccinal tissue allergie. "cellular transfer" of delayed type hypersensitivity]. 19666011443
[virus inhibition in vitro by 6-azalumazine]. 19666014906
[corneal opacities in cowpox virus keratitis]. 19665341094
[influence of n-methyl-isatin-beta- thiosemicarbazone (itsc) (marboran) on the development of vaccinal virus in cell cultures of human embryo fibroblasts. cytochemical study with the aid of acridine orange dye]. 19675590423
[alanine aminotransferase and aspartate aminotransferase activity in cultured chicken fibroblasts in the process of growing and after infection by vaccinia virus]. 19675597199
lack of "reactivating" activity in the molluscum contagiosum virus. 19675598012
the relative sensitivity of chick and rabbit tissues for the titration of vaccinia and cowpox viruses. 19675598014
vaccinia dna: separation of viral from host cell dna. 19675598023
[testing of disinfectants for virucidal power against viruses of the smallpox-vaccinia group]. 19675598875
inhibition of interferon synthesis by triethylenemelamine and 4-nitroquinoline-n-oxide. 19675602137
[interference between vaccinia virus and rabies virus; possible role of an interferon]. 19675602138
[various properties of purified and concentrated preparations of interferon]. 19675602357
[a study of interference induced by coxsackie b3 virus in experiments with animals]. 19675602358
[5-iodo-2'-deoxyuridine (idu) in the treatment of ocular infection caused by vaccinia virus]. 19675604221
[the effect of deoxyribonuclease on the incorporation of thymidine-h3 into cells infected by vaccinia virus]. 19675607290
mitosis of cultured human amnion cells after infection by variola and vaccinia viruses. 19675609367
[induction of a viral inhibitor by the action of nucleic acids extracted from normal and tumorous tissues]. 19675611513
multiplicity reactivation of vaccinia virus particles treated with nitrogen mustard.the nitrogen mustard bis(beta-chloroethyl)methylamine, a radiomimetic alkylating agent, is known for its ability to inactivate viruses in general and poxvirus in particular. these experiments show that vaccinia virus is rapidly inactivated by it. they show, in addition, that the treated virus exhibits multiplicity reactivation in l cells, closely resembling that experienced with the same virus after exposure to ultraviolet rays. these findings have come from observations of plaque titer, on the ...19675623957
effect of interferon on deoxyribonuclease induction in chick fibroblast cultures infected with cowpox virus.an exonuclease which degrades native deoxyribonucleic acid at ph 9.2 was induced in chick embryo fibroblast cultures and in human amnion cells by infection with cowpox virus. highly purified chick embryo interferon suppressed the induction of the enzyme in the homologous cell system but not in the human amnion cell cultures. "mock" interferon prepared from uninfected chicken eggs and purified in the same manner as biologically active interferon preparations had no effect on the induction of the ...19675623968
soluble antigens of vaccinia-infected mammalian cells. ii. time course of synthesis of soluble antigens and virus structural proteins.virus-induced soluble antigens produced in mammalian cells after infection with vaccinia virus can be divided into two classes on the basis of molecular weight. synthesis of the low molecular weight antigens begins early in the course of infection (1 to 2 hr), and is switched-off rather abruptly 4 to 5 hr after infection in a manner similar to that reported for the early enzymes characteristic of this same system. it was demonstrated, however, that these antigens do not include virus-induced thy ...19675623969
metabolic properties of early and late vaccinia virus messenger ribonucleic acid.in vaccinia-infected cells, 60% of the viral messenger ribonucleic acid (mrna) was associated with polyribosomes, and the remainder sedimented in a broad peak in the 30 to 74s region. the quantity of mrna in polyribosomes was sharply reduced late in the infectious cycle [9 hr postinfection (pi)] to less than 30% of the 2-hr value. however, protein synthesis proceeded at a nearly constant rate from 2 to 13 hr pi. this ability of small quantities of late mrna to support as much protein synthesis a ...19675623973
morphology of deoxyribonucleic acid extracted from cores of vaccinia virus. 19675623977
[treatment of experimental vaccinia keratitis with idu and alpha-chymotrypsin]. 19675624457
isolation of a paravaccinia virus from a cow in japan. 19675624717
enhancement of vaccinia virus plaque formation by trypsin. 19675625049
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