Publications

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the use of millipore filters in ultrastructural studies of cell cultures and viruses.a technique is described for embedding tissue culture cells that have been adsorbed or grown on millipore filters. the acetone used during the embedding process rendered the filters transparent so that specific areas or cells could be chosen with the aid of the light microscope. lymphoblastoid cells processed on the filters possessed well-defined plasma membranes and microvilli which were rarely present in cells from parallel cultures that were prepared by pelleting in the centrifuge. fibroblast ...196819866719
the use of millipore filters in ultrastructural studies of cell cultures and viruses. 196819806703
immature forms of vaccinia virus: morphological observations from thin sections of infected human skin. 196818614126
[effect of x ray irradiation on the natural resistance of white mice to a smallpox vaccine virus]. 196816541569
actinomycin analogues containing pipecolic acid: relationship of structure to biological activity.streptomyces antibioticus synthesizes a mixture of actinomycins which differ at the "imino acid" site of the peptide chains. in the presence of exogenous pipecolic acid, several new actinomycins were synthesized and 70% of the proline in the antibiotic mixture was replaced by the analogue. three new antibiotics (designated pip 1alpha, pip 1beta, and pip 2) were isolated from culture filtrates, purified, and crystallized. the molar ratio of pipecolic acid to proline was: pip 1alpha, 1:0; pip 1bet ...19684174667
disc plate assay of vaccinia antibodies. 19684176042
rubella virus and human lymphocytes in culture. 19684176262
[a simple method for quick identification of virus contamination of tissue cultures]. 19684191153
[the effect of bacterial enzymes on the stability of vaccinia virus]. 19684233173
[immunization against trachoma]. 19684233253
the prevention of early vaccinia-virus-induced cytopathic effects by inhibition of protein synthesis. 19684234470
[preparation of purified, fluid and lyophylized virus suspensions. the purification of vaccinia viruses]. 19684234953
[increased resistance of baby mice against vaccinia virus after active homologous immunization]. 19684234960
the nucleic acid type and effect of ph and hydroxylamine on canine distemper virus. 19684235309
[experimental neurovaccinal encephalitis in the rabbit. electroclinical and anatomical correlations in 9 cases]. 19684397561
the effect of purine and pyrimidine compounds on the virus-host cell interation. i. the effect on interferon production and virus multiplication. 19684387323
production of mature virus particles by escherichia coli spheroplasts infected with lipid-treated rna of ranikhet disease virus and with vaccinia and ranikhet disease viruses. 19684387325
virus multiplication and carbohydrate--oxidative metabolism. 3. study on lactate dehydrogenase in the multiplication of influenza and poxviruses. 19684387328
[inhibition of the cytopathic effect by blockade of vaccinia virus dna synthesis with 5-fluoro-2-deoxyuridine. autoradiographic studies]. 19684387862
experimental inhalation infection of germ-free piglets with vaccinia virus. 19684386021
antiviral effect of methylglyoxal-bis-guanylhydrazone. 19684386637
[experiments on the challenge of the antivaccinial transfer immunity of cell cultures by infection with variola virus. (evaluation of the antivariola potency of smallpox vaccines)]. 19684329545
malignant tumors in smallpox vaccination scars: a report of 24 cases. 19684296119
[animal experimental studies on various smallpox vaccines in a cowpox challenge experiment on white mice]. 19684301159
temperature optima of mammalian and amphibian viruses in cell cultures of homeothermic and poikilothermic origin. 19684300628
herpes simplex virus dna. 19684300878
virucidal properties of dimethyl sulfoxide. 19684300900
sensitivity of herpes simplex virus, vaccinia virus, and adenoviruses to deoxyribonucleic acid inhibitors and thiosemicarbazones in a plaque suppression test.herpes simplex and vaccinia viruses and adenovirus types 1, 2, 5, and 7 were tested by plaque suppression methods for sensitivity to halogenated deoxyuridines (5-iodo-, 5-bromo-, 5-chloro-, and 5-fluoro-), cytosine arabinoside, isatin-beta-thiosemicarbazone, and n-methylisatin-beta-thiosemicarbazone. after incubation for 12 days in hela cell cultures, vaccinia virus plaques were still readily suppressed by deoxyribonucleic acid (dna) inhibitors and thiosemicarbazones. herpes simplex virus plaque ...19684300089
antiviral activity of trichothecin. 19684299888
antiviral activity of brefeldin a and verrucarin a. 19684299889
suppression of growth of herpes simplex virus in chick embryo fibroblasts at 40 degrees c. 19684299895
comparative studies on the histological picture of lesions in chick chorio-allantoic membranes infected with vaccinia, smallpox and alastrim viruses. 19684299367
a human interferon that crosses the species line. 19684298335
[biologic activity of human interferon on the simian species in vitro and in vivo]. 19684296559
controlled double infection with unrelated animal viruses. 19684297164
simian hemorrhagic fever. 3. isolation and characterization of a viral agent. 19684297405
monkey pox. i. clinical, virologic and immunologic studies. 19684297615
new methods of production and partial purification of an antiviral substance from penicillium cyaneo-fulvum. 19684297713
[comparative study of the reproduction of viruses of the subgroup variola-vaccinia in l cells]. 19684302805
[evidence for a specific repressor in the cells of different species transformed by sv 40 virus]. 19684302945
the induction of cancer by combinations of viruses and other agents. 19684303178
antiviral activity of selected catharanthus alkaloids. 19684303510
[resistance of viruses of the subgroup smallpox-vaccinia to treaments primarily damaging the protein coat of the nucleic component of the virus]. 19684303594
localization of nucleotide phosphohydrolase activity within vaccinia. 19684299268
yaba tumor virus. i. studies on pathogenesis and immunity. 19684301427
inducers of interferon and host resistance, v. in vitro studies. 19684301592
[an autoradiographic study of proliferation of the corneal epithelium infected with vaccinia virus]. 19684301629
temperature-sensitive events in the growth of variola virus in hela cells. 19684301635
stabilization of enveloped viruses by dimethyl sulfoxide. 19684302192
[irreversible inactivation of vaccinia and poliomyelitis viruses with homologous antibodies in the presence of cofactor]. 19684302363
[review of corneal viral infection in its histopathological aspects]. 19684305404
effect of raphanin on the multiplication of some rna and dna viruses in, and interferon production by, cultured cells. 19684306944
[studies in the field of substances with antiviral activity. derivatives of 2,4-dioxo-3-oxyiminochromane]. 19684305796
[antiviral potentials. i. higher acyl derivatives of thiopurine bases and amantidine; adamantanoyl-derivatives]. 19684305907
[antiviral potentials. ii. thiosemicarbazones of substituted acetophenones]. 19684305908
new antiviral antibiotics; xanthocillin x mono- and dimethylether, and methoxy-xanthocillin x dimethylether. i. isolation and characterization. (studies on antiviral and antitumor antibiotics. v). 19684304616
[on the antimicrobial effect of peracetic acid. 5. studies on the virucidal effect]. 19684304791
sequential protein synthesis following vaccinia virus infection.inhibition of hela cell protein synthesis and the sequential synthesis of viral proteins were followed by pulse-labeling infected cells with (14)c-phenylalanine. proteins were resolved by polyacrylamide gel electrophoresis. the viral origin of native proteins was confirmed by immunodiffusion. the inhibition of host protein synthesis and the synthesis of early viral proteins occur 1 to 3 hr after infection. this early sequence of events also occurs in the presence of 5-fluorodeoxyuridine, an inhi ...19684235537
synthesis and intracellular localization of vaccinia virus deoxyribonucleic acid-dependent ribonucleic acid polymerase.the time course of vaccinia deoxyribonucleic acid (dna)-dependent ribonucleic acid (rna) polymerase synthesis and its intracellular localization were studied with virus-infected hela cells. viral rna polymerase activity could be meassured shortly after viral infection in the cytoplasmic fraction of infected cells in vitro. however, unless the cells were broken in the presence of the nonionic detergent triton-x-100, no significant synthesis of new rna polymerase was detected during the viral grow ...19684235691
antiviral activity of 9-beta-d-arabinofuranosyladenine. v. activity against intracerebral vaccinia virus infections in mice. 19684309849
effect of poxvirus infection on host cell deoxyribonucleic acid synthesis.deoxyribonucleic acid (dna) synthesis was studied in poxvirus-infected cells by measuring (14)c-thymidine incorporation into viral and host cell dna. a complete separation of the two species of dna was achieved by combining the previously used "dounce method" with a separation method based on different reannealing properties of viral and vertebrate dna. shortly after infection of hela cells with poxviruses, a burst of viral dna synthesis occurred in the cytoplasm, but a rapid inhibition of host- ...19684301310
the antiviral activity of 9-beta-d-arabinofuranosyladenine (ara-a). 19684305653
rate of inactivation of smallpox and vaccinia viruses by fixatives used in histological methods. 19684300247
viral inactivation by disulfide bond reducing agents. 19684315605
efficient filtration and sizing of viruses with membrane filters.untreated membrane filters retain viruses by adsorption, as well as by physical restriction which occurs when the pore diameter of the filter is smaller than that of the virus particle. as originally recommended by elford, membranes had to be pretreated with proteinaceous material to preclude virus adsorption. however, coating materials that prevent adsorption of certain viruses do not necessarily prevent adsorption of other viruses. in contrast to proteins, salts enhance virus adsorption. virus ...19684316012
anti-variola and anti-vaccinia principles from seeds of banakadali (ensete superbum, cheesm, musaceae). 19684301550
immune hemadsorption by cells infected with poxviruses. 19684305647
monkeypox: experimental infection in chimpanzee (pan satyrus) and immunization with vaccinia virus. 19684298203
antiviral agent from lambda-infected escherichia coli k-12. i. isolation.phagicin, which is an antiviral agent active against deoxyribonucleic acid (dna) viruses such as vaccinia and herpes simplex, has been identified as a phage internal protein. it was found in infected escherichia coli lysates, but could also be obtained by disruption of the purified infective particles after incubation with licl at 46 c for 15 min or by sonic treatment. after centrifugation at high speed, the antiviral activity was found in the dna phase and could be separated by chromatography o ...19684299120
studies of an established canine kidney-cell line. 19684301040
reversible inhibition of the reproduction of dna viruses by glycosides of 2-phenethyl alcohol and related compounds. 19684301302
multiplicity reactivation of gamma- and x-irradiated vaccinia virus in l cells. 19685634978
membrane models and membrane formation. 19685644069
differential inhibitory effects of interferon on deoxythymidine kinase induction of vaccinia-infected cell cultures. 19685644637
the action of sparsomycin and gougerotin on virus growth. 19685645577
[vaccination reaction and smallpox vaccination]. 19685650003
efficiency of the synergistic infection of l cells by groups of damaged vaccinia virus particles, mr. 19685652673
use of a new buffer in the culture of animal cells. 19685654767
effect of cytostatics on the replication of vaccinia, pseudo-rabies and sindbis viruses and on the interferon production by tissue culture cells. 19685657098
accidental vaccinia. 19685658922
cellular immunity in vaccinia infection of mice. anti-thymocyte serum effects on primary and secondary responsiveness.rabbit anti-mouse thymocyte serum suppressed host cell-mediated responsiveness to intravenously administered vaccinia virus, thereby augmenting the morbidity and mortality of this infection. it did not affect either humoral antibody or interferon production in response to vaccinia virus. no effects were noted on primary or secondary immunity to intracerebral virus inoculation.19685662010
specific interference among strains of newcastle disease virus. 3. mechanisms of interference. 19685662869
inhibition of viral growth by salicylhydroxamic acid. 19685668152
immune competence in congenital rubella: lymphocyte transformation, delayed hypersensitivity, and response to vaccination. 19685668373
haemadsorption by vaccinia virus and the vh factor in chickens. 19685675581
an adverse reaction from treating warts with vaccinia virus. 19685676077
inhibition by interferon of the uncoating of vaccinia virus. 19685677798
vaccinia as a model for membrane biogenesis. 19685677800
the immunodepressive action of lymphocytic choriomeningitis virus in mice. 19685681651
smallpox vaccination of eczema patients with attenuated live vaccinia virus. 19685683825
the relationship between poxvirus and a-type inclusion body during double infection. 19685684123
[keratitis vaccinolosa]. 19685685941
soluble antigens of vaccinia-infected mammalian cells. 3. relation of "early" and "late" proteins to virus structure.the structural proteins of vaccinia virus can be divided into two classes on the basis of their times of synthesis in the infected cell. the production of one of these classes of proteins begins prior to the onset of viral deoxyribonucleic acid (dna) replication. these are referred to as "early" proteins. synthesis of the second class of structural proteins follows the onset of viral dna replication; hence, the term "late" proteins for this class. we are able, by immunological procedures, to ide ...19685688397
the response of mice to the intravenous injection of cowpox virus. 19685689130
[enhanced resistance of babymice to variolavirus after active immunization with vaccinia]. 19685691137
clumping and sedimentation patterns: manifestations of haemagglutination. 19685693228
[on the endangerment of the human embryo by the vaccinia virus]. 19685695246
vaccination response in rabbits related to quantity of vaccinia virus particles and passage level. 19685696289
antiviral effect of acetone. 19685698685
[smallpx vaccination]. 19685700509
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