Publications

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mutations to 8-azaguanine resistance induced in cultured chinese hamster cells by alpha particles. 19725064768
repair of a dna complex from x-irradiated chinese hamster cells. 19724541706
the in vivo cytogenetic effects of 252 cf on liver and bone marrow of the chinese hamster. 19725084001
the retention, distribution, dose and cytogenetic effects of 241 amacitrate in the chinese hamster. 19725083994
damage and repair of dna in 5-bromodeoxyuridine-labeled chinese hamster cells exposed to fluorescent light.illumination of chinese hamster cells with fluorescent light after 5-bromodeoxyuridine incorporation leads to extensive single-strand breakage in the dna of the exposed cells. the rate of production of single-strand breaks is dependent on the extent to which thymine is replaced by 5-bromouracil. at least some of the breaks observed with alkaline gradients are probably produced in vivo and are probably not contingent upon alkaline hydrolysis since breakage can be demonstrated with neutral gradien ...19725063839
potentiation of drug effect by tween 80 in chinese hamster cells resistant to actinomycin d and daunomycin. 19725030820
progesterone-induced alterations of oogenesis in the chinese hamster. 19725025463
synthesis and degradation of microtubule protein in synchronized chinese hamster cells. 19725063679
experimental evolution of cell populations of chinese hamster treated with colchicine. induction of high degree of ploidy and a phase-specific lethal effect. 19724660935
radiation-induced division delay in synchronized chinese hamster ovary cells in monolayer culture. 19725063489
a search for chromosome damage following exposure of chinese hamster cells to high intensity, pulsed ultrasound. 19725063346
the development of the diencephalon of the chinese hamster. 19725055997
chinese hamster liver glutamine synthetase. purification, physical and biochemical properties. 19724401699
regulation of the udp-glucose-4-epimerase activity in chinese hamster cells. 19724337424
the morphological and chtogenetic effects of laser power at 2650 a on chinese hamster cells in vitro. 19725063192
effect of caffeine on the induction of mutations in chinese hamster cells by ultraviolet light. 19725062851
the induction of 8-azaguanine-resistant mutants in cultured chinese hamster cells by ultraviolet light. the effect of changes in post-irradiation conditions. 19725062850
[cytophotometric studies on the kinetics of feulgen's hydrolysis of metaphase chromosomes and spermatozoa in the spermatogenesis of the chinese hamster]. 19725050907
radiation-induced chromosome abberations in chinese hamster leukocytes. a comparison of in vivo and in vitro exposures. 19724537717
immune cytolysis and x irradiation: independent lethal action in chinese hamster cells in vitro. 19725062045
[distribution of 5-bromodeoxyuridine-induced chromosome aberrations along chinese hamster chromosomes]. 19725020132
induced changes in the rates of uridine- 3 h uptake and incorporation during the g 1 and s periods of synchronized chinese hamster cells.the rates of uridine-5-(3)h incorporation into rna and the rates of uridine uptake into the acid-soluble pool during the cell cycle of v79 chinese hamster cells were examined. cells cultured on eagle's minimal essential medium supplemented with fetal calf serum, lactalbumin hydrolysate, glutamine, and trypsin displayed rates of incorporation and uptake which increased only slightly during g(1) and accelerated sharply as dna synthesis commenced. in contrast, cells cultured on minimal essential me ...19725009516
survival response of asynchronous and synchronous chinese hamster cells exposed to fluorescent light following 5-bromodeoxyuridine incorporation. 19725062702
[autoradiographic analysis of chromosome localization in interphase nuclei of cricetulus griseus and vicia faba]. 19725062399
[spiralization of chinese hamster chromosomes after 5-bromodeoxyuridine treatment of cells in 2 consecutive mitotic cycles]. 19725062395
[transformation in vitro of a new cell line from the chinese hamster embryo (c.h.e.): evolution of the transplantability, the karyotype and the cell surface]. 19724622417
lymphocyte cultures from chinese hamster (cricetulus griseus). 19724111089
recovery and repair in chinese hamster cells following uv-irradiation. 19725066419
[topography of the peritoneal organs of the chinese minihamster (cricetulus griseus milne edwards 1867)]. 19725063830
cell cycle compartment analysis of chinese hamster cells in stationary phase cultures. 19725062785
[chromosome analysis of cultures of chinese hamster cells after treatment with lead acetate]. 19725062073
chromosome pulverization in micronuclei induced by tritiated thymidine.cultures of a pseudodiploid cell line (don) of chinese hamster origin were exposed to varying doses of tritiated thymidine (tdr-(3)h) for relatively long periods of time. in addition to previously observed chromosomal aberrations) such as breaks and reunions, a substantial number of interphasic cells with micronuclei and of metaphases associated with pulverized chromosomes was found; both phenomena were dependent on exposure time to and concentration of tdr-(3)h. the former phenomenon appeared t ...19725061680
relation between ultrastructure and viability of frozen-thawed chinese hamster tissue-culture cells. 19725045646
a two-factor hypothesis of freezing injury. evidence from chinese hamster tissue-culture cells. 19725045639
[behavioral ontogenesis of the chinese dwarf hamster, cricetulus griseus (milne edwards, 1867)]. 19725040089
[chinese hamster (cricetulus griseus): a spontaneously diabetic animal]. 19725029365
asynchronous centromere division in the chinese hamster. 19725024687
drug response, dihydrofolate reductase, and cytogenetics of amethopterin-resistant chinese hamster cells in vitro. 19725007683
the effect of cyclamate and saccharin on the chromosomes of a chinese hamster cell line. 19724680637
differential spiralization along mammalian mitotic chromosomes. i. budr-revealed differentiation in chinese hamster chromosomes. 19724672290
the development of the diencephalon of the chinese hamster. an investigation of the validity of the criteria of subdivision of the brain. 19724540788
chromosomes of six primary sarcomas induced in the chinese hamster by 7,12-dimethylbenz(a)anthracene. 19724376140
[micronucleus test and chromosomal analysis in somatic and gonosomal cells of the chinese hamster after treatment with cyclophosphamide (author's transl)]. 19724130849
chromosome identification in a chinese hamster pseudodiploid cell line (chef-125). 19724116209
banding patterns of chinese hamster chromosomes revealed by new techniques. 19724112624
replicon origins in chinese hamsters cell dna. i. labeling procedure and preliminary observations. 19724263528
[malignant cellular transformation and karyologic modifications: the contribution of intraspecific somatic hybridization in chinese hamsters]. 19724676768
in vitro leucocyte cultures of syrian and chinese hamsters. 19725064119
nature of the iron requirement for chinese hamster v79 cells in tissue culture medium. 19734734766
relationship between the ratio of parental chromosomes and parental doubling times in chinese hamster-mouse somatic cell hybrids. 19734736587
surface antigens of mammalian cells as genetic markers. ii.a second surface antigen, b(l), lethal in the presence of specific antibody and complement has been identified on some human cells and shown to behave as a good genetic marker. it is autosomal, unlinked to the human a(l) antigen previously described, and unlinked to 15 other human genes. the a(l) antigen, which is linked to the lactic dehydrogenase a gene, is found on the hela, the cultured human fibroblast, and in small amounts on the human lymphocyte. b(l) occurs on hela cells, on cultured hum ...19734736830
independent loss of human hexosaminidases a and b in man-chinese hamster somatic cell hybrids. 19734737100
a cytological study of the karyotype of spleen cells from scrapie-affected chinese hamsters. 19734738622
caffeine inhibition of postreplication repair of n-acetoxy-2-acetylaminofluorene-damaged dna in chinese hamster cells. 19734741935
[the development of cell classes in the liver of rats and chinese hamsters (author's transl)]. 19734777261
comparative studies of organs in the european hamster (cricetus cricetus l.), the syrian golden hamster (mesocricetus auratus w.) and the chinese hamster (cricetulus griseus m.). 19734779674
cytological mapping of the genes assigned to the human a 1 chromosome by use of radiation-induced chromosome breakage in a human-chinese hamster hybrid cell line. 19734785162
cell-cycle-dependent variations of deoxyribonucleoside triphosphate pools in chinese hamster cells. 19734795783
effect of amino acid and serum deprivation on the regulation of rna synthesis in cultured chinese hamster ovary cells. 19734796172
a comparison of the interaction of chinese hamster fibroblasts with human and bovine transferrins, and conalbumin (chick-egg transferrin). 19734796207
asparagine-requiring tumor cell lines and their non-requiring variants: cytogenetics, biochemistry and population dynamics.asparagine-requiring jensen and walker rat tumor cells and their asparagine-independent variants have been analyzed. the following results were obtained: (1) both cell lines have very low levels of asparagine synthetase, and non-requiring revertants isolated from these lines have elevated levels of the enzyme. (2) no differences in chromosome number were detected between the parent jensen line and five jensen non-requiring revertants isolated from it. (3) both jensen and walker cells undergo asp ...19734798091
cellular reactions of o6-methylguanine, a product of some alkylating carcinogens.cultures of a purine-requiring mutant of chinese hamster ovary cells (cho-104b), randomly bred hamster embryo cells, or escherichia coli b(s-1) were treated with non-toxic doses of (3)h-labelled o(6)-methylguanine. dna and rna were isolated and subjected to enzymic digestion to nucleosides at ph8. the products of digestion were analysed by ion-exchange chromatography on columns of dowex 50 (nh(4) (+) form) at ph8.9. no (3)h-labelled o(6)-methylguanosine was detected in nucleic acid digests. (3)h ...19734590203
transfer of genetic information by purified metaphase chromosomes.transfer of genetic information from isolated mammalian chromosomes to recipient cells has been demonstrated. metaphase chromosomes isolated from chinese hamster fibroblasts were incubated with mouse a(9) cells containing a mutation at the hypoxanthine-guanine phosphoribosyl transferase (hprt) locus. cells were plated in a selective medium, resulting in death of all unaltered parental a(9) cells. however, colonies of cells containing hypoxanthine phosphoribosyl transferase (ec 2.4.2.8) appeared ...19734515624
chromosomal interchanges induced by radiation in spermatogonial cells and leukocytes of mouse and chinese hamster. 19734515916
regional localization of loci for human pgm and 6pgd on human chromosome one by use of hybrids of chinese hamster-human somatic cells.the human gene loci phosphoglucomutase(1) (pgm(1), ec 2.7.5.1) and 6-phosphogluconate dehydrogenase (6pgd, ec 1.1.1.43), which are located on human chromosome one, have been assigned to a specific region of the short arm of that chromosome, by use of a hybrid cell line derived from a chinese hamster cell line deficient in hypoxanthine phosphoribosyl transferase and a strain of human diploid fibroblasts. cytogenetic analysis of a hybrid clone maintained for about 50 generations in vitro revealed ...19734517931
identification of chick chromosomes in cell hybrids formed between chick erythrocytes and adenine-requiring mutants of chinese hamster cells.when chick erythrocytes were fused with adenine-requiring mutants of chinese hamster cells of two different complementation classes and grown in adenine-free medium for 1 week or longer, mitotic cells were observed containing both chick and chinese hamster metaphase chromosomes within a single cell. stable hybrid clones were subsequently isolated that possessed, in addition to a complete chinese hamster genome, a single specific chick chromosome. hybrids resulting from fusions involving differen ...19734517942
chromosome and chromatid exchanges in chinese hamster cells. 19734348023
the heterogeneous distribution of acid hydrolases within a homogeneous population of cultured mammalian cells.1. chinese-hamster ovary fibroblasts were cultured to provide a homogeneous cell population. homogenates obtained from these cells were fractionated by centrifugation techniques and the resulting fractions were analysed for protein and for enzymes representative of certain subcellular particles. 2. unlike those in rat liver homogenates, the mitochondrial and lysosomal populations proved impossible to separate by differential centrifugation owing to the similarity of their sedimentation propertie ...19734353380
expression of malignancy in interspecies chinese hamster x mouse cell hybrids. 19734355218
proline biosynthesis: multiple defects in chinese hamster ovary cells. 19734356052
microbial flora and viral contact status of chinese hamsters (cricetulus griseus). 19734357853
localization of genes on human chromosomes by studies of human-chinese hamster somatic cell hybrids. assignment of pgm3 to chromosome c6 and regional mapping of the pgd, pgm1 and pep-c genes on chromosome a1. 19734358963
a temperature-sensitive function in a chinese hamster line affecting dna synthesis. 19734359532
mutations affecting the structure of hypoxanthine: guanine phosphoribosyltransferase in cultured chinese hamster cells.14 clones resistant to 8-azaguanine, isolated from mutagenically treated cultured cells from chinese hamsters, were tested for loss of enzymic and immunological activities of hypoxanthine: guanine phosphoribosyltransferase. three of the clones had no enzymic activity but reacted strongly with antiserum prepared against the enzyme (crm(+)), indicating the presence of a defective enzyme protein, probably caused by a mutation in its structural gene. the other 11 mutants had little or no enzymic or ...19734119786
expression of endogenous rna c-type virus group-specific antigens in mammalian cells.highly sensitive and specific radioimmunoassays are described for quantitation of the intraspecies determinants of several mammalian c-type viral group-specific (gs) antigens. an interspecies (gs-3) immunoassay has been developed which has both the broad reactivity and great sensitivity necessary for detection of c-type viruses where intraspecies gs assays are not available. by using these immunoassays, the expression of endogenous virus-specified gs antigens in mammalian cells of different spec ...19734127032
[characterization of a hybrid cell line, "human leukemia-chinese hamster"]. 19734364713
mutagenicity and carcinogenicity of n-methyl-n'-nitro-n-nitrosoguanidine i. induction of chromosome aberrations and mitotic anomalies in chinese hamster ovary cells.cultured chinese hamster ovary (cho) cells were exposed to different concentrations of n-methyl-n'-nitro-n-nitrosoguanidine (mnng) for either 24 hr or 6 days. for cytological consequences of mnng exposure, cho cells were treated for 24 hr and allowed a 24 hr recovery period prior to analysis; for the estimation of cytotoxicity of mnng, cells were treated for 6 days followed by a 6 day recovery period. the cytotoxic effect of mnng based on the colony-forming ability of treated cells showed a semi ...1973422929
isolation and characterization of revertants of the mammalian temperature sensitive leucyl-trna synthetase mutant tshl.nine spontaneous and seven ethyl methanesulfonate induced revertants of the chinese hamster ovary cell line mutant (tshl), which possesses a temperature sensitive leucyl-trna synthetase, were isolated and characterized with respect to growth rate, leucyl-trna synthetase activity and thermolability, intracellular leucine pool size, and rrna content. although most revertants had increased leucyl-trna synthetase activity, and of those tested, all but one had increased thermostability, each appears ...1973422661
enhanced intestinal fat absorption in diabetic chinese hamsters. 19734773551
effect of 2450-mhz microwaves on the radiation response of x-irradiated chinese hamsters. 19734703889
evidence from triton x-100 polyacrylamide gel electrophoresis that histone f2a2, not f2b, is phosphorylated in chinese hamster cells. 19734796852
dna cross-linking in chinese hamster cells exposed to near ultraviolet light in the presence of 4,5',8-trimethylpsoralen. 19734798023
temporal organization of dna in chinese hamster cells: cell-cycle dependent association of dna with membrane. 19734798022
[mutagenic effect of o-methylhydroxylamine in chinese hamster cell cultures]. 19734807121
dna synthesis and mitosis in a temperature sensitive chinese hamster cell line. 19734798033
letter: damage and repair of dna in 5-bromodeoxyuridine-labeled chinese hamster cells exposed to fluorescent light. 19734796887
isolation and properties of a glucosamine-requiring mutant of chinese hamster lung cells. 19734788622
[synchronization of chinese hamster cell cultures with colcemid]. 19734781678
growth and radiation survival characteristics of v79-171b chinese hamster cells: a possible influence of intercellular contact. 19734767132
on the properties of a membrane-associated protein kinase from chinese hamster ovary cells. 19734356721
morphological transformation of enucleated chinese hamster ovary cells by dibutyryl adenosine 3',5'-monophosphate and hormones. 19734357169
the response of chinese hamster (ovary) cells to protracted irradiation from 252cf and 60co. 19734761145
derivation of tk- clones from revertant tk+ mammalian cells.in order to obtain a large collection of chinese hamster cell clones defective in thymidine kinase (tk(-)), brdu(r) selection experiments have been performed on wild-type and revertant tk(+) cell lines. no clones (< 10(-9)) were obtained from the wild-type tk(+) cell line by single-step selection. in contrast, revertant tk(+) clones readily gave rise to stable tk(-) derivatives (1 - 2 x 10(-4)). both wild-type and revertant tk(+) clones spontaneously yielded 8-ag(r) colonies with the same freque ...19734359755
enhancement by caffeine of n-methyl-n-nitrosourea-induced mutations and chromosome aberrations in chinese hamster cells. 19734356743
dna-degradation and excision repair in gamma-irradiated chinese hamster ovary cells. 19734518364
effect of neocarzinostatin on v-79 chinese hamster cells in vitro. 19734803216
inhibition of post-replication repair of alkylated dna by caffeine in chinese hamster cells but not hela cells. 19734796966
caffeine inhibition of postreplication repair of n-acetoxy-2-acetylamino fluorene-damaged dna in chinese hamster cells. 19734795392
the effect of ploidy on chemical mutagenesis in cultured chinese hamster cells. 19734753423
effect of streptozotocin in the chinese hamster (cricetulus griseus). 19734355607
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