TitleAbstractYear(sorted ascending)
the relation of protein synthesis to radiation-induced division delay in chinese hamster cells. 19705530793
[functional morphology of the chromosomes of cultivated mammalian cells. iv. nucleolus-organizing region of the x-chromosomes of the chinese hamster in long-term cultures of somatic cells]. 19705512958
regulation of initiation of dna synthesis in chinese hamster cells : ii. induction of dna synthesis and cell division by isoleucine and glutamine in g(1)-arrested cells in suspension culture.suspension cultures of chinese hamster cells (line cho), which had stopped dividing and were arrested in g(1) following growth to high cell concentrations in f-10 medium, could be induced to reinitiate dna synthesis and to divide in synchrony upon addition of the appropriate amounts of isoleucine and glutamine. both amino acids were required to initiate resumption of cell-cycle traverse. deficiencies in other amino acids contained in f-10 medium did not result in accumulation of cells in g(1), i ...197019866743
somatic cell hybridization: pattern of chromosome replication in viable chinese hamster x armenian hamster hybrids. 19705531479
uv-absorption and quinacrine mustard fluorescence patterns for chromosome aberration study in chinese hamster. 19705496280
actinomycin d and radiation fractionation studies in asynchronous and synchronized chinese hamster cells. 19705490498
separation of nuclei representing different phases of the growth cycle from unsynchronized mammalian cell cultures.nuclei have been isolated from unsynchronized cultures of chinese hamster fibroblasts after varying intervals of growth following the incorporation of thymidine (-3)h for 20 min. these nuclei were fractionated by unit gravity sedimentation in a stabilizing density gradient of sucrose, and fractions were analyzed for the concentration of nuclei, dna, and radioactivity. a more rapidly sedimenting population of nuclei in the g(2) phase of the cell cycle was separated from a group of nuclei in the g ...19705513550
the ultrastructure of the brain in the diabetic chinese hamster with special reference to synaptic abnormalities. 19704097216
isolation of low molecular weight, methylated ribonucleic acids from 10s to 30s particles of chinese hamster cell fractions. 19705534312
comparison of lethality and chromosomal damage induced by x-rays in synchronized chinese hamster cells in vitro. 19705466865
protection by cysteamine against mitotic delay and chromosomal aberrations induced by x-rays in synchronized chinese hamster cells. 19705465551
[breeding performance of normal and diabetic chinese hamsters (cricetulus griseus)]. 19705452392
repair replication in chinese hamster cells after damage from ultraviolet light. 19705498523
density invariance of cultured chinese hamster cells with stage of the mitotic cycle.isopycnic banding of chinese hamster line cho cells in ficoll gradients shows that a population in balanced, exponential growth is very homogeneous with respect to density, the coefficient of variation of the density distribution spectrum being less than 5% of the mean reduced density (i.e. density minus one). similar measurements on synchronized cultures indicate that reduced density varies by less than 2% around the life cycle. the mean density of cho cells in f-10 growth medium is calculated ...19705465290
regulation of initiation of dna synthesis in chinese hamster cells. i. production of stable, reversible g1-arrested populations in suspension culture.suspension cultures of chinese hamster cells (line cho) were grown to stationary phase (approximately 8-9 x 10(5) cells/ml) in f-10 medium. cells remained viable (95%) for at least 80 hr in stationary phase, and essentially all of the cells were in g(1) upon resuspension or dilution with fresh medium, the cells were induced to resume traverse of the life cycle in in synchrony, and the patterns of dna synthesis and division were similar to those observed in cultures prepared by mitotic selection. ...19705460461
x-ray survival of cultured chinese hamster cells resuming growth after plateau phase. 19705463519
the relative radiosensitivity of the nucleus and cytoplasm of chinese hamster fibroblasts. 19705463516
radiosensitivity of mammalian cells. iv. effects of x-irradiation on the dna synthetic period in synchronized cells.the effect of x-irradiation on the timing of dna synthesis in the chinese hamster ovary cells has been investigated. mitotically synchronized cells irradiated in mitosis or early g(1) exhibited a fixed, dose-independent (150-2000 rad) delay of 1.6 hr in entry into s, while the duration of s was unaffected. cells irradiated during late g(1) or the first 0.8 hr of s were not affected either in time of initiation or duration of s. however, when cells 0.8 hr or more into s were irradiated, completio ...19705452354
epidemiological studies of the chinese hamster. 19705432350
metabolic abnormalities in the pancreatic islets and livers of the diabetic chinese hamster. 19704914658
[the postnatal development of cricetulus griseus]. 19705517748
a comparison of radiation-induced reproductive death and chromosome exchanges in chinese hamster cells at room temperature and in liquid nitrogen. 19705310882
cellular resistance to actinomycin d in chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies. 19705533992
dna synthetic pattern in the nucleolus. ii. chinese hamster cells. 19705466481
a new cell line derived from newborn chinese hamster lung tissue. 19705452405
two forms of repair of dna in mammalian cells following irradiation.when chinese hamster cells are lysed on top of an alkaline sucrose gradient, in time a fairly discrete dna-containing molecular species is released from an apparently more complex material. small doses of x-radiation speed the resolution of this complex while large doses degrade the material released from it. incubation after irradiation reverses both effects.19705461576
low-molecular-weight, methylated ribonucleic acid species in chinese hamster cell fractions absorb to bentonite. 19705461485
[functional morphology of chromosomes in cultured mammalian cells. ii. study of chinese hamster aneuploid cell chromosomes using 5-bromodeoxyuridine]. 19705450755
the response of histone fractions to x-irradiation in cultured chinese hamster cells. 19705461505
animal cells: noncorrelation of length of g1 phase with size after mitosis.the interval between mitosis and initiation of dna synthesis (g(1)) varied over a fourfold range for chinese hamster ovary cells, an established line. this was not because of size differences. synchlronous cells of different sizes began dna synthesis at similar times after mitosis. a novel technique of centrifugation for separating cells according to size is described.19705409485
aneuploidy and polyploidy in germ-line cells of the male chinese hamster (cricetulus griseus). 19705535796
[experiences with the chinese hamster (cricetulus griseus) in the breeding for diabetes research]. 19705534904
[breeding of the chinese hamster according to the collar method]. 19705534903
breeding chinese hamsters (cricetulus griseus) in monogamous pairs. 19705534902
[testicular changes in a diabetic chinese hamster]. 19705512322
[chinese hamster as an experimental animal]. 19705512319
[future role of the chinese hamster in research]. 19705512312
[blood picture of the chinese hamster]. 19705512311
[carcinogenic effect of diethyl- and dibutylnitrosamine in the chinese hamster]. 19705512310
[cytogenetic studies of the bone marrow and fibroblast cultures from the chinese hamster]. 19705512309
[use of the chinese hamster for inhalation experiments]. 19705512308
[electrocardiogram, phonocardiogram and pneumogram of the chinese hamster]. 19705512307
[functional morphology of mammalian chromosomes in cultured cells. 3. x-chromosomes in short-term diploid and long-term aneuploid chinese hamster cell cultures]. 19705508636
[chemical mutagenesis in mammals. the chinese hamster bone marrow as an in vivo test system. hematological findings after treatment with trenimon]. 19705490354
the distribution of sister chromatids at mitosis in chinese hamster cells. 19705480727
chromosomal damage in chinese hamster cells grown in u.v.-irradiated medium. 19705461556
growth and observations of chinese hamster seminiferous epithelium in vitro. 19705417691
recovery of chinese hamster cells from ultra-violet irradiation damage. 19705311614
the influence of post-irradiation conditions on the survival of chinese hamster cells after gamma-irradiation. 19705310732
morphologic changes in the pancreatic islets of the chinese hamster in spontaneous diabetes and some experimental conditions. 19704934164
[bibliography on the chinese hamster]. 19704934162
[hybridization of mammalian somatic cells and spermatozoa. penetration and early morphological changes of stallion spermatozoa in chinese hamster cells]. 19714325612
induction of nuclear envelopes around metaphase chromosomes after fusion with interphase cells.the process of cellular fusion induced by sendai virus in chinese hamster cells (don line) afforded us the opportunity to study nuclear envelope formation around metaphase sets in the presence of interphase nuclei, when chromosome pulverization failed to occur in such multinucleate cells. morphologically, the enveloped metaphase chromosomes resembled a normal telophase nucleus, though minor differences prompted us to call it telophase-like. electron microscopic observations demonstrated that the ...19714329517
enzyme electrophoresis on cellulose acetate gel: zymogram patterns in mgh-mouse and man--chinese hamster somatic cell hybrids. 19714331030
genetics of somatic mammalian cells: lethal antigens as genetic markers for study of human linkage groups.the antigen that causes killing of at least 98% of a human cell population treated with a 1% solution of a specific rabbit antiserum in the presence of complement is a sensitive genetic marker. the rapid loss of human chromosomes in human-chinese hamster cell hybrids makes possible a convenient test of linkage relationships with this marker. hybrid clones with and without the lethal antigen were isolated and analyzed. in 76 clones and subclones studied, 41 carried both the lethal antigen and the ...19714332008
integration of simian virus 40 deoxyribonucleic acid into the deoxyribonucleic acid of primary infected chinese hamster cells.simian virus 40 deoxyribonucleic acid (dna) became associated in an alkaline-stable form with the dna of chinese hamster embryo cells at 15 to 20 hr post-infection, at the time when cell dna synthesis and t antigen were induced. the integration process was not inhibited by d-arabinosyl cytosine and was only partially inhibited by cycloheximide.19714332141
[comparative biochemical study on the diabetogenic effect of streptozotocin in mice, rats, chinese hamsters and guinea pigs]. 19714334222
reinitiation within one cell cycle of the deoxyribonucleic acid synthesis induced by simian virus 40.the infection of secondary cultures of chinese hamster cells with simian virus 40 (sv40) induces the appearance of cells with polyploid deoxyribonucleic acid (dna) content or chromosomal component within one cell generation. the mechanism of this phenomenon was studied by the use of 5-bromodeoxyuridine (budr) incorporation as a dna density marker. when cultures were treated with (14)c-budr and colcemide and harvested at 48 hr postinfection, only hybrid and light dna molecules were found in contr ...19714366428
wheat germ agglutinin titres of normal and transformed chinese hamster cells and human and guinea pig erythrocytes: variations related to cell preparation. 19714339592
heparan sulfates of cultured cells. i. membrane-associated and cell-sap species in chinese hamster cells. 19714253009
effect of 5-bromodeoxyuridine on hyaluronic acid synthesis of a clonal hybrid line of mouse and chinese hamster in culture. 19714258000
[comparative morphological studies on the diabetogenic effect of streptozotocin in rats, chinese hamsters, guinea pigs and rabbits]. 19714258515
experimental transmission of scrapie to voles and chinese hamsters. 19714099889
mammalian peptide chain termination. ii. codon specificity and gtpase activity of release vitro peptide chain termination with release factor preparations from rabbit reticulocytes, guinea pig liver, or chinese hamster liver is directed with uaaa, uaga, or ugaa, suggesting that uaa, uag, and uga are terminator condons for mammalian cells. purified release factor from rabbit reticulocytes has ribosomaldependent gtpase activity, which is stimulated by uaaa. gtp hydrolysis appears requisite for in vitro peptide chain termination in mammals.19715276771
cytogenetic effects of cyclohexylamine and n-oh-cyclohexylamine on human leucocytes and chinese hamster bone marrow. 19715283624
loss of human genetic markers in man--chinese hamster somatic cell hybrids. 19715286856
nucleoli of diploid cell strains. thei normal ultrastructure and the effects of toyocamycin and actinomycin d.nucleoli of cultured chinese hamster or mouse cells in early passages had a loosely reticular substructure. within the reticulum small, irregularly shaped, light fibrillar zones occurred which were contiguous with denser fibrillar zones. these denser zones appeared to be connected in some places to the particulate material which composed the mass of the nucleolus. generally, electron-transparent spaces separated the particulate zones from the fibrillar areas. treatment with toyocamycin, an agent ...19715104724
distinctive characteristics of nucleoli of two established cell lines.nucleoli of cultured cells of the established lines kb and l were found to possess a distinctive fine structural organization. the major portion of the nucleolar volume was composed of compact, particulate material. spheroidal fibrillar zones about 0.4 micro in diameter occurred within the particulate mass. these fibrillar zones had a central light area and a denser rim. toyocamycin treatment, which sharply inhibited the appearance of newly synthesized rna in the cytoplasm, caused the gradual di ...19715104725
x-linkage of human phosphoglycerate kinase confirmed in man-mouse and man-chinese hamster somatic cell hybrids. 19715132070
resistance of chinese hamsters to hymenolepis microstoma and its reversal by immunosuppression. 19715157159
induction of alkaline phosphatase by 5-bromodeoxyuridine in a hybrid line between mouse and chinese hamster in culture. 19715170775
chemical mutagenesis. the chinese hamster bone marrow as an in vivo test system. ii. correlation with in vitro results on chinese hamster fibroblasts and human fibroblasts and lymphocytes. 19715545036
immune cytolysis in relation to the growth cycle of chinese hamster cells. 19715560386
sedimentation of dna released from chinese hamster cells.under high ph and high salt conditions, chinese hamster cells lyse and release a dna-containing material of large molecular weight. with increasing lysis time, a smaller material is resolved from the large one. relative to t4 dna, the smaller is estimated to be approximately 2 x 10(8) daltons (number average). from a comparison of radiation data, the target size of the larger is about 15 times that of the smaller (probably a lower limit estimate). in addition to concentration of alkali, temperat ...19714997648
ultrastructural analysis of mitotic spindle elongation in mammalian cells in vitro. direct microtubule counts.the mitotic spindle of many mammalian cells undergoes an abrupt elongation at anaphase. in both cultured rat kangaroo (strain ptk(1)) and chinese hamster (strain don-c) fibroblasts, the distance from pole to pole at metaphase doubles during anaphase and telophase. in order to determine the organization and distribution of spindle microtubules during the elongation process, cells were fixed and flat embedded in epon 812. selected cells were photographed with the phase-contrast microscope and then ...19714939523
cytogenetic analysis of a chinese hamster-mouse hybrid cell. 19714940437
spatial distribution of biological effect n a 3.9-gev nitrogen ion beam.a beam of nitrogen ions obtained with the princeton particle accelerator was used for the irradiation of chinese hamster (m3-1) cells in monolayer culture. the 3.9-billion-electron-volt (gev) beam passed along the monolayer, so that ions were stopped in the culture. a sharply defined zone of extensive cell destruction occurred in the last centimeter of the beam path.19715133729
mutagenicity to mammalian cells of epoxides and other derivatives of polycyclic hydrocarbons.the cytotoxicity and mutagenicity of several polycyclic hydrocarbons and their k-region derivatives were tested in a clone of chinese hamster cells; the production of clones resistant to 8-azaguanine was used as the marker for mutagenesis. in the series related to benz(a)anthracene, the k-region epoxide was highly mutagenic, and the phenol was less mutagenic; the hydrocarbon and cis and trans-dihydrodiols were not mutagenic. seven resistant clones were isolated and retained their drug-resistance ...19715289256
comparative studies on the chinese hamster bone marrow after treatment with phenylbutazone and cyclophosphamide. 19715144633
evidence for linkage between glucose 6-phosphate dehydrogenase and hypoxanthine-guanine-phosphoribosyl transferase loci in chinese hamster cells. 19715116523
an ultracytochemical and ultrastructural study of epithelial cells in ductuli efferentes of chinese hamster. 19714111152
[protein synthesis by the mitotic apparatus in a culture of chinese hamster fibroblasts]. 19715167150
[mitotic cycle parameters in monolayer cultures of chinese hamster cells]. 19715168463
[synthesis of dna and proliferation during prolonged cultivation of chinese hamster cells]. 19715168462
[suppression by actinomycin d of rna synthesis at different stages of the mitotic cycle in chinese hamster cell cultures]. 19715168460
[incorporation of h3-actinomycin d into chinese hamster cells in vitro]. 19715168459
[relation of spiralization of chinese hamster chromosomes to dose and time of action of 5-bromodeoxyuridine in the mitotic cycle]. 19715167368
dna damage and repair following irradiation: the effect of 5-bromodeoxyuridine in cultured chinese hamster cells. 19715165688
extension of the pre-dna synthetic phase of the cell cycle as a consequence of dna alkylation in chinese hamster cells: a possible mechanism of dna repair. 19715156329
radiosensitization with 5-bromodeoxyuridine of chinese hamster cells x-irradiated during different phases of the cell cycle. 19715165872
mutation to 8-azaguanine resistance induced by -radiation in a chinese hamster cell line. 19715110771
the effects of bleomycin on survival and cell progression in chinese hamster cells in vitro. 19714107188
potentiation of x-ray killing by 5-bromodeoxyuridine in chinese hamster cells: a reduction in capacity for sublethal damage accumulation. 19715561933
inhaled ozone as a mutagen. i. chromosome aberrations induced in chinese hamster lymphocytes. 19715097513
effects of caffeine on the induction of mutation in chinese hamster cells by ultraviolet light. 19715563947
inhibition of dna synthesis in synchronized chinese hamster cells treated in g1 with cycloheximide. 19715106077
further changes in differentiation state accompanying the conversion of chinese hamster cells of fibroblastic form by dibutyryl adenosine cyclic 3':5'-monophosphate and hormones.the morphological conversion in vitro of chinese hamster ovary cells to a fibroblast form by a relatively large amount of dibutyryl adenosine cyclic 3':5'-monophosphate, or by a combination of small amounts of this compound and testosterone, is attended by appearance of the following additional properties: acquisition of strict contact inhibition of growth; reorientation of the random growth pattern into one in which cells grow parallel to their long dimension; disappearance of the randomly dist ...19714327009
dna replication in chinese hamster cells: evidence for a single replication fork per replicon. 19714253728
ultraviolet light-induced division delayed in synchronized chinese hamster cells.the age-dependent, ultraviolet light (uvl) (254 nm)-induced division delay of surviving and nonsurviving chinese hamster cells was studied. the response was examined after uvl exposures adjusted to yield approximately the same survival levels at different stages of the cell cycle, 60% or 30% survival. cells irradiated in the middle of s suffered the longest division delay, and cells exposed in mitosis or in g(1) had about the same smaller delay in division. cells irradiated in g(2), however, wer ...19715106108
ultraviolet light-induced division delay in synchronized chinese hamster cells. 19715105184
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