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[chromosome analysis of cultures of chinese hamster cells after treatment with lead acetate]. 19725062073
chromosome pulverization in micronuclei induced by tritiated thymidine.cultures of a pseudodiploid cell line (don) of chinese hamster origin were exposed to varying doses of tritiated thymidine (tdr-(3)h) for relatively long periods of time. in addition to previously observed chromosomal aberrations) such as breaks and reunions, a substantial number of interphasic cells with micronuclei and of metaphases associated with pulverized chromosomes was found; both phenomena were dependent on exposure time to and concentration of tdr-(3)h. the former phenomenon appeared t ...19725061680
relation between ultrastructure and viability of frozen-thawed chinese hamster tissue-culture cells. 19725045646
a two-factor hypothesis of freezing injury. evidence from chinese hamster tissue-culture cells. 19725045639
[behavioral ontogenesis of the chinese dwarf hamster, cricetulus griseus (milne edwards, 1867)]. 19725040089
[chinese hamster (cricetulus griseus): a spontaneously diabetic animal]. 19725029365
asynchronous centromere division in the chinese hamster. 19725024687
drug response, dihydrofolate reductase, and cytogenetics of amethopterin-resistant chinese hamster cells in vitro. 19725007683
the effect of cyclamate and saccharin on the chromosomes of a chinese hamster cell line. 19724680637
differential spiralization along mammalian mitotic chromosomes. i. budr-revealed differentiation in chinese hamster chromosomes. 19724672290
the development of the diencephalon of the chinese hamster. an investigation of the validity of the criteria of subdivision of the brain. 19724540788
chromosomes of six primary sarcomas induced in the chinese hamster by 7,12-dimethylbenz(a)anthracene. 19724376140
[micronucleus test and chromosomal analysis in somatic and gonosomal cells of the chinese hamster after treatment with cyclophosphamide (author's transl)]. 19724130849
chromosome identification in a chinese hamster pseudodiploid cell line (chef-125). 19724116209
banding patterns of chinese hamster chromosomes revealed by new techniques. 19724112624
replicon origins in chinese hamsters cell dna. i. labeling procedure and preliminary observations. 19724263528
[malignant cellular transformation and karyologic modifications: the contribution of intraspecific somatic hybridization in chinese hamsters]. 19724676768
in vitro leucocyte cultures of syrian and chinese hamsters. 19725064119
nucleoli of diploid cell strains. thei normal ultrastructure and the effects of toyocamycin and actinomycin d.nucleoli of cultured chinese hamster or mouse cells in early passages had a loosely reticular substructure. within the reticulum small, irregularly shaped, light fibrillar zones occurred which were contiguous with denser fibrillar zones. these denser zones appeared to be connected in some places to the particulate material which composed the mass of the nucleolus. generally, electron-transparent spaces separated the particulate zones from the fibrillar areas. treatment with toyocamycin, an agent ...19715104724
distinctive characteristics of nucleoli of two established cell lines.nucleoli of cultured cells of the established lines kb and l were found to possess a distinctive fine structural organization. the major portion of the nucleolar volume was composed of compact, particulate material. spheroidal fibrillar zones about 0.4 micro in diameter occurred within the particulate mass. these fibrillar zones had a central light area and a denser rim. toyocamycin treatment, which sharply inhibited the appearance of newly synthesized rna in the cytoplasm, caused the gradual di ...19715104725
x-linkage of human phosphoglycerate kinase confirmed in man-mouse and man-chinese hamster somatic cell hybrids. 19715132070
resistance of chinese hamsters to hymenolepis microstoma and its reversal by immunosuppression. 19715157159
induction of alkaline phosphatase by 5-bromodeoxyuridine in a hybrid line between mouse and chinese hamster in culture. 19715170775
ultrastructural analysis of mitotic spindle elongation in mammalian cells in vitro. direct microtubule counts.the mitotic spindle of many mammalian cells undergoes an abrupt elongation at anaphase. in both cultured rat kangaroo (strain ptk(1)) and chinese hamster (strain don-c) fibroblasts, the distance from pole to pole at metaphase doubles during anaphase and telophase. in order to determine the organization and distribution of spindle microtubules during the elongation process, cells were fixed and flat embedded in epon 812. selected cells were photographed with the phase-contrast microscope and then ...19714939523
cytogenetic analysis of a chinese hamster-mouse hybrid cell. 19714940437
sedimentation of dna released from chinese hamster cells.under high ph and high salt conditions, chinese hamster cells lyse and release a dna-containing material of large molecular weight. with increasing lysis time, a smaller material is resolved from the large one. relative to t4 dna, the smaller is estimated to be approximately 2 x 10(8) daltons (number average). from a comparison of radiation data, the target size of the larger is about 15 times that of the smaller (probably a lower limit estimate). in addition to concentration of alkali, temperat ...19714997648
mammalian peptide chain termination. ii. codon specificity and gtpase activity of release factor.in vitro peptide chain termination with release factor preparations from rabbit reticulocytes, guinea pig liver, or chinese hamster liver is directed with uaaa, uaga, or ugaa, suggesting that uaa, uag, and uga are terminator condons for mammalian cells. purified release factor from rabbit reticulocytes has ribosomaldependent gtpase activity, which is stimulated by uaaa. gtp hydrolysis appears requisite for in vitro peptide chain termination in mammals.19715276771
cytogenetic effects of cyclohexylamine and n-oh-cyclohexylamine on human leucocytes and chinese hamster bone marrow. 19715283624
loss of human genetic markers in man--chinese hamster somatic cell hybrids. 19715286856
chemical mutagenesis. the chinese hamster bone marrow as an in vivo test system. ii. correlation with in vitro results on chinese hamster fibroblasts and human fibroblasts and lymphocytes. 19715545036
immune cytolysis in relation to the growth cycle of chinese hamster cells. 19715560386
reinitiation within one cell cycle of the deoxyribonucleic acid synthesis induced by simian virus 40.the infection of secondary cultures of chinese hamster cells with simian virus 40 (sv40) induces the appearance of cells with polyploid deoxyribonucleic acid (dna) content or chromosomal component within one cell generation. the mechanism of this phenomenon was studied by the use of 5-bromodeoxyuridine (budr) incorporation as a dna density marker. when cultures were treated with (14)c-budr and colcemide and harvested at 48 hr postinfection, only hybrid and light dna molecules were found in contr ...19714366428
wheat germ agglutinin titres of normal and transformed chinese hamster cells and human and guinea pig erythrocytes: variations related to cell preparation. 19714339592
[hybridization of mammalian somatic cells and spermatozoa. penetration and early morphological changes of stallion spermatozoa in chinese hamster cells]. 19714325612
induction of nuclear envelopes around metaphase chromosomes after fusion with interphase cells.the process of cellular fusion induced by sendai virus in chinese hamster cells (don line) afforded us the opportunity to study nuclear envelope formation around metaphase sets in the presence of interphase nuclei, when chromosome pulverization failed to occur in such multinucleate cells. morphologically, the enveloped metaphase chromosomes resembled a normal telophase nucleus, though minor differences prompted us to call it telophase-like. electron microscopic observations demonstrated that the ...19714329517
enzyme electrophoresis on cellulose acetate gel: zymogram patterns in mgh-mouse and man--chinese hamster somatic cell hybrids. 19714331030
genetics of somatic mammalian cells: lethal antigens as genetic markers for study of human linkage groups.the antigen that causes killing of at least 98% of a human cell population treated with a 1% solution of a specific rabbit antiserum in the presence of complement is a sensitive genetic marker. the rapid loss of human chromosomes in human-chinese hamster cell hybrids makes possible a convenient test of linkage relationships with this marker. hybrid clones with and without the lethal antigen were isolated and analyzed. in 76 clones and subclones studied, 41 carried both the lethal antigen and the ...19714332008
integration of simian virus 40 deoxyribonucleic acid into the deoxyribonucleic acid of primary infected chinese hamster cells.simian virus 40 deoxyribonucleic acid (dna) became associated in an alkaline-stable form with the dna of chinese hamster embryo cells at 15 to 20 hr post-infection, at the time when cell dna synthesis and t antigen were induced. the integration process was not inhibited by d-arabinosyl cytosine and was only partially inhibited by cycloheximide.19714332141
[comparative biochemical study on the diabetogenic effect of streptozotocin in mice, rats, chinese hamsters and guinea pigs]. 19714334222
heparan sulfates of cultured cells. i. membrane-associated and cell-sap species in chinese hamster cells. 19714253009
effect of 5-bromodeoxyuridine on hyaluronic acid synthesis of a clonal hybrid line of mouse and chinese hamster in culture. 19714258000
[comparative morphological studies on the diabetogenic effect of streptozotocin in rats, chinese hamsters, guinea pigs and rabbits]. 19714258515
experimental transmission of scrapie to voles and chinese hamsters. 19714099889
inhaled ozone as a mutagen. ii. effect on the frequency of chromosome aberrations observed in irradiated chinese hamsters. 19715139962
dibutylnitrosamine carcinogenesis in syrian golden and chinese hamsters. 19715540601
spatial distribution of biological effect n a 3.9-gev nitrogen ion beam.a beam of nitrogen ions obtained with the princeton particle accelerator was used for the irradiation of chinese hamster (m3-1) cells in monolayer culture. the 3.9-billion-electron-volt (gev) beam passed along the monolayer, so that ions were stopped in the culture. a sharply defined zone of extensive cell destruction occurred in the last centimeter of the beam path.19715133729
mutagenicity to mammalian cells of epoxides and other derivatives of polycyclic hydrocarbons.the cytotoxicity and mutagenicity of several polycyclic hydrocarbons and their k-region derivatives were tested in a clone of chinese hamster cells; the production of clones resistant to 8-azaguanine was used as the marker for mutagenesis. in the series related to benz(a)anthracene, the k-region epoxide was highly mutagenic, and the phenol was less mutagenic; the hydrocarbon and cis and trans-dihydrodiols were not mutagenic. seven resistant clones were isolated and retained their drug-resistance ...19715289256
comparative studies on the chinese hamster bone marrow after treatment with phenylbutazone and cyclophosphamide. 19715144633
evidence for linkage between glucose 6-phosphate dehydrogenase and hypoxanthine-guanine-phosphoribosyl transferase loci in chinese hamster cells. 19715116523
an ultracytochemical and ultrastructural study of epithelial cells in ductuli efferentes of chinese hamster. 19714111152
[protein synthesis by the mitotic apparatus in a culture of chinese hamster fibroblasts]. 19715167150
[mitotic cycle parameters in monolayer cultures of chinese hamster cells]. 19715168463
[synthesis of dna and proliferation during prolonged cultivation of chinese hamster cells]. 19715168462
[suppression by actinomycin d of rna synthesis at different stages of the mitotic cycle in chinese hamster cell cultures]. 19715168460
[incorporation of h3-actinomycin d into chinese hamster cells in vitro]. 19715168459
[relation of spiralization of chinese hamster chromosomes to dose and time of action of 5-bromodeoxyuridine in the mitotic cycle]. 19715167368
dna damage and repair following irradiation: the effect of 5-bromodeoxyuridine in cultured chinese hamster cells. 19715165688
extension of the pre-dna synthetic phase of the cell cycle as a consequence of dna alkylation in chinese hamster cells: a possible mechanism of dna repair. 19715156329
radiosensitization with 5-bromodeoxyuridine of chinese hamster cells x-irradiated during different phases of the cell cycle. 19715165872
mutation to 8-azaguanine resistance induced by -radiation in a chinese hamster cell line. 19715110771
the effects of bleomycin on survival and cell progression in chinese hamster cells in vitro. 19714107188
potentiation of x-ray killing by 5-bromodeoxyuridine in chinese hamster cells: a reduction in capacity for sublethal damage accumulation. 19715561933
inhaled ozone as a mutagen. i. chromosome aberrations induced in chinese hamster lymphocytes. 19715097513
effects of caffeine on the induction of mutation in chinese hamster cells by ultraviolet light. 19715563947
inhibition of dna synthesis in synchronized chinese hamster cells treated in g1 with cycloheximide. 19715106077
further changes in differentiation state accompanying the conversion of chinese hamster cells of fibroblastic form by dibutyryl adenosine cyclic 3':5'-monophosphate and hormones.the morphological conversion in vitro of chinese hamster ovary cells to a fibroblast form by a relatively large amount of dibutyryl adenosine cyclic 3':5'-monophosphate, or by a combination of small amounts of this compound and testosterone, is attended by appearance of the following additional properties: acquisition of strict contact inhibition of growth; reorientation of the random growth pattern into one in which cells grow parallel to their long dimension; disappearance of the randomly dist ...19714327009
dna replication in chinese hamster cells: evidence for a single replication fork per replicon. 19714253728
ultraviolet light-induced division delayed in synchronized chinese hamster cells.the age-dependent, ultraviolet light (uvl) (254 nm)-induced division delay of surviving and nonsurviving chinese hamster cells was studied. the response was examined after uvl exposures adjusted to yield approximately the same survival levels at different stages of the cell cycle, 60% or 30% survival. cells irradiated in the middle of s suffered the longest division delay, and cells exposed in mitosis or in g(1) had about the same smaller delay in division. cells irradiated in g(2), however, wer ...19715106108
ultraviolet light-induced division delay in synchronized chinese hamster cells. 19715105184
effects of cycloheximide on x-ray induction of chromatid exchanges in synchronous chinese hamster cells. 19715104870
absence of "permanent" recovery in certain chinese hamster fibroblasts. 19715103881
[tooth development, molar erosion and age determination by teeth in the chinese dwarf hamster (cricetulus griseus)]. 19715097313
ultrastructure of the nucleolus during the chinese hamster cell cycle.changes in the structure of the nucleolus during the cell cycle of the chinese hamster cell in vitro were studied. quantitative electron microscopic techniques were used to establish the size and volume changes in nucleolar structures. in mitosis, nucleolar remnants, "persistent nucleoli," consisting predominantly of ribosome-like granular material, and a granular coating on the chromosomes were observed. persistent nucleoli were also observed in some daughter nuclei as they were leaving telopha ...19714933472
microphotometric and autoradiographic studies on the cell cycle and cell size during growth and decline of chinese hamster cell cultures. 19715104443
[studies on pregnancy and offspring of the spontaneously diabetic chinese hamster]. 19715108106
new class of purine mutants of chinese hamster ovary cells.mutants of chinese hamster ovary cells (cho/pro(-)) were isolated after mutagenesis with n-methylnitrosoguanidine and selection by the bromodeoxyuridine technique. six of these were mutants classified as purine-requiring. the metabolic block appears to be early in the purine biosynthetic pathway. the mutants do not appear to be genetically identical.19715547727
atp pool levels in synchronously growing chinese hamster cells. 19715555578
migration of newly synthesized rna during mitosis. ii. chinese hamster fibroblasts. 19715554033
molecular hybridization of chinese hamster 5s, 4s and "pulse-labelled" rna in cytological preparations. 19715554032
regulation of growth in chinese hamster cells by a local inhibitor. 19715554030
the response of chinese hamster cells to n-methyl-n'-nitro-n-nitrosoguanidine. 19715165147
[migration of newly synthesized rna during mitosis. ii. chinese hamster fibroblasts]. 19715105515
cellular resistance to daunomycin in chinese hamster cells in vitro. 19715102828
the establishment and chromosome analysis of a new cell line of chinese hamster from spontaneous transformation in vitro. 19715563334
hybridization of actinomycin d- and amethopterin-resistant chinese hamster cells in vitro. 19715547219
chromosomal aberrations and mortality of x-irradiated mammalian cells: emphasis on repair.chromosomal aberrations induced by x-rays in synchronized chinese hamster cells correlated well with mortality as the radiosensitivity was made to vary by a factor of 4 by treating the cells with colcemid or 5-bromodeoxyuridine and by irradiating the cells in different parts of the cell cycle. 37% survival was observed when the cells sustained about one aberration per cell. furthermore, the positive correlation was observed during repair of damage. repair was measured by the reduction in damage ...19715276778
[penetration of isolated metaphase chromosomes into chinese hamster tissue culture cells]. 19715105427
the effects of x-rays on the synthesis of dna, rna, and proteins in synchronized chinese hamster cells. 19715103339
deoxyribonucleic acid synthesis in ultraviolet-light-irradiated chinese hamster cells.two mammalian cell lines, chinese hamster ovary (cho) which can recover colony-forming ability between fractionated doses of ultraviolet light (uv), and chinese hamster b-14faf28 which cannot recover, were tested for the ability to bypass uv-induced photoproducts in dna during postirradiation dna synthesis. the molecular weight distributions of newly synthesized dna in uv-irradiated populations of both cell lines showed evidence for photoproduct bypass. hence, the bypass mechanism does not corre ...19715103274
homology between sv40 dna and dna of normal and sv40-transformed chinese hamster cells. 19715543953
the effects of 1,3-bis(2-chloroethyl)-1-nitrosurea on survival and cell progression in chinese hamster cells. 19715545270
buoyant density of dna synthesized at different stages of s phase in chinese hamster cells. 19715542655
methylation and synthesis of transfer ribonucleic acid in synchronized chinese hamster fibroblasts. 19715542642
quantitative aspects of the repair of alkylated dna in cultured mammalian cells. ii. non-semiconservative dna synthesis ('repair synthesis') in hela and chinese hamster cells following treatment with alkylating agents. 19715156326
quantitative aspects of the repair of alkylated dna in cultured mammalian cells. i. the effect on hela and chinese hamster cell survival of alkylation of cellular macromolecules. 19715156325
[obtaining isolated metaphase chromosomes from chinese hamster cells growing in vitro]. 19715105426
morphological transformation of chinese hamster cells by dibutyryl adenosine cyclic 3':5'-monophosphate and testosterone.treatment of chinese hamster ovary cells in vitro with dibutyrl adenosine cyclic 3':5'-monophosphate converts the culture from one of compact, randomly oriented cells that grow in multilayers to a monolayer of elongated, fibroblast-like cells growing parallel to one another. testosterone propionate, which has a similar though smaller effect at high concentrations and after prolonged incubation, potentiates the action of dibutyryl cyclic amp even when added at very low concentrations. the transfo ...19714322607
[hybridization between 2 cell lines of the chinese hamster with different tumorigenic powers]. 19714995370
a technique for increasing the number of mitoses in the bone marrow of the chinese hamster by injection of pertussis vaccine and phytohemagglutinin. 19715578204
differential response of constitutive and facultative heterochromatin in the manifestation of mitomycin induced chromosome aberrations in chinese hamster cells in vitro. 19715574765
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