| [oscillospira guillermondii, a rumen bacteria: ultrastructural study of the trichome and of sporulation]. | | 1976 | 178884 |
| effects of estrogen and testosterone on specific prolactin binding in the kidneys and adrenal of rats. | the effects of estradiol benzoate in the female rat, testosterone propionate in the male rat, and castration in both sexes on specific prolactin binding sites in the particulate membranes of the kidneys and adrenals were studied. castration resulted in a significant increase in prl binding activity in the kidneys of both males and females, and in a significant increase in prl binding activity in the adrenals of the females. the increase in prl binding with castration and the decrease seen with t ... | 1976 | 179168 |
| [study of the indirect complement fixation test for use in the differentiation of foot-and-mouth disease viruses and the determination of immunity]. | studies were carried out to establish the optimal conditions for the indirect complement-fixation test (icft) and explore the possibility to use the test in differentiating the foot-and-mouth disease (fmd) viruses and checking the immunity obtained in survivals or in animals that had been vaccinated against fmd. it was demonstrated that the proper use of icft necessitates in turn the use of a minimal amount of antigen, which in the presence of 1-2 e homologous hyperimmune serum completely binds ... | 1975 | 179191 |
| immunosuppressive effect of intra-lymphatic irradiation. | the effect of intra-lymphatic administration of lipiodol-l131 on the number of t and b lymphocytes, and on the in vivo response to common antigens and to dncb, was investigated in uremic patients in the pre-transplant period. t lymphocytes have been detected by rosette formation with sheep erythrocytes (e) and b lymphocytes by rosette formation with erythrocytes sensitized with antibody and complement (eac). after irradiation it was observed a lymphopenia due to a statistically significant decre ... | 1975 | 179310 |
| establishment and characterization of an epstein-barr virus (ebc)-negative lymphoblastoid b cell line (bja-b) from an exceptional, ebv-genome-negative african burkitt's lymphoma. | an epstein-barr virus (ebv)-negative lymphoblastoid cell line (lcl), bja-b, was established from an african burkitt's lymphoma (bl) which contained no detectable ebv dna and did not express the ebv specified antigen ebna, bja-b cells grow in typically large, flat clumps. all carry surface-bound immunoglobulins, a b lymphocyte marker, and do not form rosettes with sheep erythrocytes. after infection of bja-b cells by ebv the infected cells may produce either ebv-determined nuclear antigen (ebna) ... | 1975 | 179629 |
| pathology of lymphosarcoma in sheep induced with bovine leukemia virus. | sixty-nine sheep were infected with bovine leukemia virus from bovine lymphosarcoma materials. twenty-four developed lymphosarcoma and died from 13 to 66 (average, 29) months later. circulating lymphocytes were increased to leukemia levels (70,000 to 403,000/cu mm blood) in only eight sheep within 2 to 3 months of death. various lymph nodes and visceral organs including heart, abomasum, uterus, kidneys, and urinary tract were commonly affected as in cattle with the adult form of lymphosarcoma. i ... | 1976 | 179703 |
| the role of sheep and goats in the epizootiology of foot-and-mouth disease in kenya. | the pathogenicity of two bovine field strains of virus for indigenous goats was examined in the laboratory. the goats failed to develop clinical disease or become virus carriers although the majority showed a definite immune response. a field survey in a foot-and-mouth disease enzootic area showed that the indigenous sheep and goat populations were frequently exposed to infection as evidenced by a high proportion of sero-positive animals but the incidence of virus carriers was very low in goats ... | 1976 | 180176 |
| appearance of igg (fc) receptor(s) on cultured human fibroblasts infected with human cytomegalovirus. | cultured human diploid fibroblasts (wi-38) after infection with human cytomegalovirus (cmv) but not when uninfected, could hemadsorb sheep red blood cells (srbc) coated with rabbit anti-srbc igg. the adsorption of igg-coated srbc to virus-infected cells was completely abolished if the tests were carried out in the simultaneous presence of rabbit antiserum elicited against cmv. normal sera of rabbit or human origin as well as purified human igg but not fab fragment of human igg could also abolish ... | 1976 | 180179 |
| viral diseases of the skin, 1975: a 25-year perspective. | most of the major advances in modern virology during the past 25 years have been due principally to the development of refined laboratory techniques and tools and have provided a fund of new knowledge and information about the nature of viral infection and pathogenesis. one group of viruses of interest to dermatologists, the herpesviruses, is undergoing intensive biochemical investigation to determine whether it is carcinogenic. as a result of the success of the world health organization's campa ... | 1976 | 180187 |
| cytochromes in brain mitochondria from lambs with enzootic ataxia. | | 1976 | 180253 |
| effect of adrenocorticotrophic hormone on the in vivo output of adenosine 3'5' cyclic monophosphate and corticosteroids by the sheep adrenal gland. | | 1976 | 180337 |
| direct photo-affinity labeling of cyclic nucleotide binding proteins with guanosine-3',5'-monophosphate. | | 1976 | 180550 |
| adenovirus infection in lambs. i. epizootiology of the disease. | | 1976 | 180729 |
| effects of acth and its o-nitrophenyl sulphenyl derivative on adrenocortical function in vivo. | both acth and nps-acth in which the single tryptophan residue of the hormone is modified were able to stimulate adrenal corticosterone concentration to the same extent in hypophysectomized rats, although a higher dose of nps-acth was required. acth stimulated adrenal cyclic amp levels 120-fold in hypophysectomized rats whereas nps-acth caused a marginal increase. in the case of acth, low doses of the hormone capable of producing maximal stimulation of corticosterone synthesis did not produce any ... | 1976 | 180742 |
| age-dependent mechanical and biochemical responses to glucagon. | the age-dependent relationships between glucagon-induced alterations in myocardial mechanics and adenylate cyclase activity in fetal and newborn lambs and adult sheep were evaluated. glucagon substantially augmented the force of contraction of ventricular myocardium isolated from the adult but not from the fetus or newborn. similarly, substantial increases in the spontaneous frequency of contraction and tension were observed in adult atrial strips, but not in the fetus or newborn. comparable act ... | 1976 | 180816 |
| [experimental studies of heart muscle following use of extracorporeal circulation]. | | 1975 | 180850 |
| cyclophosphamide-induced amelioration of marek's disease in marek's disease-susceptible chickens. | bursa- and thymus-dependent functions were examined in marek's disease (md)-susceptible normal chickens and in chickens treated with 5 and 16 mg of cyclophosphamide (cy) at the time of hatching. chickens not exposed to marek's disease virus (mdv) and treated with cy temporarily lost mitogenic response to concanavalin a but regained full response after 5 weeks. bursa-dependent functions, such as presence of germinal centers in spleen and cecal tonsils, morphologic features of bursa, and sheep red ... | 1976 | 180852 |
| modification of native sheep liver fructose-1,6-bisphosphatase by subtilisin. | | 1976 | 180987 |
| regulation of immune responses. ii. the cellular basis of cyclic amp effects on humoral immunity. | | 1976 | 181147 |
| maternal immunoglobulins and parainfluenza 3 virus inhibitors in the nasal and lachrymal secretions and serum of newborn lambs. | concentrations of igg, igm and iga were measured in the serum, nasal secretions and lachrymal secretions of suckled newborn lambs. the major immunoglobulin constituent of precolostral serum was igm. maternal immunoglobulins, of which igg was predominant, reached peak values on day 1 of life and then declined over the next 3 weeks. half lives were calculated as: igg, 13-7 days; igm, 4-1 days; and iga 1-8 days. no immunoglobulin was detectable in nasal or lachrymal secretions prior to sucking but ... | 1976 | 181185 |
| multiple forms of corticotropin (adrenocorticotropic hormone, acth) and their significance. | big corticotropin (adrenocroticotropic hormone, acth), an immunoreactive form of acth with low biological activity and which elutes in the void volume on sephadex g-50 gel filtration, is found in plasma and extracts of human pituitary and tumour. controlled tryptic digestion of big acth releases a product with full corticotropic activity which is indistinguishable from the (1-39) acth with respect to size, charge and susceptibility to tryptic digestion. immunoreactive acth, predominantly in the ... | 1976 | 181223 |
| immunological and biochemical studies of meningococcal c polysaccharides isolated by diethylaminoethyl chromatography. | meningococcal c polysaccharides isolated from the broth supernatant of c1+ and c1- strains by a combination of sepharose 4b and diethylaminoethyl-52 chromatography are antigenically identical to the group c antigen isolated by the cetavlon procedure. immunizations result in the induction of precipitating, hemagglutinating, and bactericidal antibodies in rabbits and sheep and hemagglutinating and bactericidal antibodies in rabbits and sheep and hemagglutinating and bactericidal antibodies in gerb ... | 1976 | 181322 |
| detection of virus-specific immunoglobulins using a doubly labeled fluorescein-125i antibody. | commercially prepared fluorescein-labeled antihuman antibodies were labed with 125i and used to compre specific herpes simplex virus antibody titers as determined by indirect fluorescent antibody and radioimmunoassay techniques. total virus-specific immunoglobulin and virus-specific immunoglobulin g titers did not vary by more than one twofold dilution when compared by the two methods. | 1976 | 181400 |
| studies of lesions produced in the brains of colostrum deprived lambs by clostridium welchii (cl. perfringens) type d toxin. | | 1976 | 181408 |
| cellular immunity in chronic theiler's virus central nervous system infection. | after (ic) inoculation of the da strain of tmev, sjl/j mice develop chronic cns infection with marked mononuclear cell infiltration of spinal cord leptomeninges and white matter and concomitant demyelination. in the present study the temporal course of cell-mediated and humoral immune responses to virus were measured in this infection. it was shown that chronic tmev infection is associated with the development of immunologically specific spleen cell reactivity as judged by in vitro incorporation ... | 1976 | 181490 |
| blood corticosteroids in australian marsupial and placental mammals and one monotreme. | peripheral blood corticosteroid levels were determined in nine species of australian marsupial (eastern grey kangaroo, black-tailed, bennett's and pademelon wallabies, quokka, wombat, koala and western native and tiger cats), one species of monotreme (echidna) and one placental australian mammal (dingo). animals were obtained or bled with minimal disturbance and came from areas considered to have adequate sodium content of the vegetation. aldosterone, corticosterone, cortisol, 11-deoxycorticoste ... | 1976 | 181514 |
| [immunological cell surface markers in infectious mononucleosis (author's transl)]. | using a direct immunofluorescence technique and a spontaneous rosette formation with sheep red blood cells it could be demonstrated that the large mononuclear cells in infectious mononucleosis consisted mainly of t-lymphocytes. it is likely that infectious mononucleosis represents a primary b-lymphcoyte infection with the epstein-barr virus like in the burkitt lymphoma. in contrast to this malignant lymphoma, interaction in infectious mononucleosis leads to a secondary t-lymphocyte proliferation ... | 1976 | 181637 |
| biosynthesis of collagen and its alterations in pathological states. | the biosynthesis of collagen involves a number of unique post-translational modifications which are catalyzed by many specific enzymes. the main steps in collagen biosynthesis are transcription and translation, hydroxylations of prolyl and lysyl residues, glycosylations of hydroxylysyl residues, chain association and disulphide bonding, triple helix formation, secretion of procollagen into the extracellular matrix, conversion of procollagen into collagen, specific aggregation of collagen molecul ... | 1976 | 181643 |
| preparation and utilization of isolated hepatocytes for the study of the sheep liver metabolism. | | 1976 | 181754 |
| radioligand receptor assay of fsh. | the assay of fsh by a radioligand receptor assay (rla) using homogenates of rat testicular tissue incubated for 17 h at 21 degrees c has been assessed. chloramine-t or lactoperoxidase were used for iodination. the assay gave linear dose-response lines between 30 and 2000 ng sheep fsh/tube, and there was usually no major interference by lh. two batches of labelled fsh, however, gave assays in which lh showed a striking interaction with fsh. when these batches were avoided and fsh and lh were mixe ... | 1976 | 181933 |
| transport of amino acids and catecholamines in relation to metabolism and transmission. | | 1976 | 181957 |
| experimental infection of lambs with a sheep adenovirus isolate closely related to type-2 bovine adenovirus. ii. postmortem and histopathological examinations. | | 1975 | 181974 |
| effects of dibutyrylcyclic amp on the in vitro primary response of mouse spleen cells to sheep erythrocytes. | exogenously added n6, 02'-dibutyryladenosine-3'-5'-cyclic phsophate (dbcamp) exerted a biphasic effect on the in vitro primary response of mouse spleen cells to sheep erythrocytes (srbc). high concentrations of dbcamp were markedly suppressive, whereas lower concentrations brought about significant increases in the peak numbers of antibody-forming cells. the kinetics of the response were not altered by dbcamp. a direct effect of dbcamp on bone-marrow derived lymphocytes was suggested because thi ... | 1976 | 182111 |
| inhibition of antibody-complement-mediated killing of tumor cells by hormones. | line 1, a chemically induced guinea pig hepatoma, is susceptible to killing by anti-forssman immunoglobulin m antibody and guinea pig complement. when these tumor cells are pretreated at 37 degrees with 10(-4) to 10(-11) m concentrations of the polypeptide hormone insulin, with the catecholamine l-epinephrine-hcl, or with the glucocorticoid steroids hydrocortisone sodium succinate or prednisolone sodium succinate, the cells show a marked reduction in their suseptibility to killing by antibody an ... | 1976 | 182362 |
| lactogenic and growth hormone-like activities in pregnancy determined by radioreceptor assays. | factors with growth hormone and lactogenic activities have been identified in serum samples and placental extracts of 9 species using a radioreceptor assay for prolactin or lactogens (rra-prl) and one for growth hormone-like activity (rra-gh). the concentrations of placental lactogen (pl) and growth hormone-like activity (ghla) in pregnancy were different in each species. the levels of pl began to rise at or before mid-pregnancy and either remained elevated until term (hamster, goat, sheep, monk ... | 1976 | 182467 |
| intermediary metabolism of adipose tissue. | metabolism of ruminant adipocytes involves the synthesis and mobilization of lipids. rates of lipid synthesis from the uptake of preformed fatty acids (via lipoprotein lipase) and de novo synthesis of fatty acids are related to the energy balance. acetate is the major carbon source for fatty acid synthesis with nadph originating from the pentose cycle and the isocitrate cycle. ruminant adipose tissue lacks the ability to utilize for lipogenesis those substrates that generate mitochondrial acetyl ... | 1976 | 182555 |
| pathogenesis of visna: review and speculation. | | 1976 | 182557 |
| maedi and visna in sheep. | | 1976 | 182560 |
| some final comments on visna-maedi aleutian disease and scrapie. | | 1976 | 182561 |
| the detailed structure of visna-maedi virus. | | 1976 | 182562 |
| visna-maedi virus infection in cell cultures and in laboratory animals. | | 1976 | 182563 |
| vaccination by the non-parenteral route of virus disease in the veterinary field. | after a brief reference to the importance of the non-parenteral route of vaccination of domestic animals in general, the author deals, for each animal species separately, with the most important vaccines utilised by this method of administration. on the basis of bibliographical data, he describes the history of this use, discusses the results of the application in the field and draws the relative conclusions. | 1976 | 182589 |
| the uptake and metabolism of glucose, maltose and starch by the rumen ciliate epidinium ecaudatum caudatum. | [14c]glucose taken up by epidinium ecaudatum caudatum was found in the pool, in the protozoal polysaccharide and in the bacteria associated with the protozoa. the amount incorporated into the polysaccharide depended on the square of the glucose concentration. evidence was obtained that glucose was probably taken up initially into the pool unchanged, and then rapidly converted into glucose 6-phosphate and maltose which were subsequently hydrolysed to glucose. [14c]-maltose was taken up at 20 to 3 ... | 1976 | 182907 |
| measurement of adenylate cyclase activity in ram spermatozoa. | | 1976 | 183000 |
| positive differential heterophile antibody test. persistence in a symptomatic patient. | a patient who had documented mononucleosis in june 1971 has been persistently symptomatic since that time, with easy fatigability and weight loss. he has also had a positive differential heterophile antibody test for mononucleosis for 14 months. although no evidence for active estein-barr virus (ebv) infection was discovered, the possibility of a chronic ebv infection is discussed. | 1976 | 183027 |
| clostridium perfringens exotoxins. iii. binding of theta-toxin to erythrocyte membrane. | when clostridium perfringens theta-toxin was incubated with sheep erythrocytes the toxin activity disappeared before lysis, the fact of which suggests fixation of the toxin to erythrocyte membranes. 2. theta-toxin lost its activity by binding to cell membranes, and the membrane constituted inhibitor of theta-hemolysis was neither a protein, a carbohydrate nor a phosphatide, but was cholesterol. from these results this report proposes that the theta-toxin binding site of erythrocytes should be ch ... | 1975 | 183032 |
| non-endemic burkitts's lymphoma. a b-cell tumor related to germinal centers. | to investigate the nature of non-endemic burkitt's lymphoma, we examined neoplastic cells from eight american patients for receptors for sheep erythrocytes (e), complement (eac), and fc fragment of lgg (iggea), and for surface immunoglobulins (slg) and hydrolytic enzymes. in addition, we reviewed 47 biopsies and 17 autopsies from american patients to ascertain patterns of involvement by tumor in lymph nodes, spleens and peyer's patches. neoplastic cells in all cases studies bore monoclonal surfa ... | 1976 | 183112 |
| localization and specificity of binding of subprimate placental lactogen in rabbit tissues. | a search for specific placental lactogen binding was undertaken in tissues obtained from late pregnant rabbits using the placental lactogens from sheep, cows, and human beings. 125i-labeled ovine lactogen exhibited highest specific binding to the adrenal gland (57.8%), followed by liver (21.5%), ovary (19.9%), mammary gland (15.9%), uterus (12.2%), kidney (8.8%), brain (8.5%), and adipose tissue (7.9%). in liver and mammary gland, the displacement curves for ovine and human lactogen were identic ... | 1976 | 183216 |
| plasma lipoproteins of lambs and sheep. | the major plasma lipoproteins of the adult sheep were high density lipoprotein (76%) having alpha-mobility on electrophoresis and low density lipoprotein (20%) having beta-mobility. chylomicrons and very low density lipoproteins were minor constituents (less than 5%). the postabsorptive hyperlipidaemia in suckling lambs is mainly a result of increased concentration of low density and high density lipoproteins although the relative contribution of very low density lipoproteins was increased to 7- ... | 1976 | 183230 |
| phospholipase a activity in human and ovine uterine tissues. | phospholipase a was assayed in crude lysosomal fractions of human decidua, amnion, chorion and myometrium. activity was present in all the tissues and was highest in decidua and amnion which contained enzymes with ph optima of 6.5-8.0 and 7.2 respectively. comparison of the activities in tissues obtained before labor with others obtained during labor showed no differences. in sheep, the fetal membranes contained a greater activity of phospholipase a than placenta and myometrium. stimulation of t ... | 1976 | 183240 |
| detection of estrogen binding in human mammary carcinoma by immunofluorescence: a new technic utilizing the binding hormone in a polymerized state. | detection of neoplastic cells with the ability to bind estrogen has been accomplished utilizing the immunofluorescence technic and polymerized estradiol phosphate. biopsies from 10 patients with the more common varieties of breast cancer have been studied and show excellent correlation with independently performed tritiated estradiol receptor assays. preliminary results show that many mammary carcinomas are composed of heterogenous cell populations which vary in their estrogen binding capacities ... | 1976 | 183254 |
| [effect of thymosterin a on the immunological reaction of mice]. | proliferaiton of thymus-dependent lymphocytes and immunological reaction of the line cba mice immunized with sheep erythrocytes was studied as affected by thymosterol a. the data obtained confirmed the authors' assumptions on a stimulation effect of thymosterol a on division of thymocytes. introduction of the mentioned preparation against a background of the antigenic aciton of sheep erythrocytes causes an increase in the amount of cells synthesizing hemolysins more than by 60% as compared to th ... | 1976 | 183318 |
| local and systemic opsonic adherent, hemagglutinating and rosette forming activity in mice induced by respiratory immunization with sheep red blood cells. | the humoral response in mice after intranasal (in) instillation of sheep red blood cells (srbc) was compared to that produced by intraperitoneal route of immunization. study of opsonic adherent (passive indirect cytophilic) and hemagglutinating antibody levels in serum and bronchial washings after repeated challenge with srbc showed that serum antibody titers following respiratory immunization does not differ from the general pattern of a humoral antibody response. the bronchial wash antibody ti ... | 1976 | 183401 |
| comparative studies on ovine and bovine c-type particles. | | 1975 | 183669 |
| replication of bovine leukemia virus in monolayer cell cultures. | | 1975 | 183699 |
| induction of lymphoid tumors in sheep with cell-free preparations of bovine leukemia virus. | | 1975 | 183702 |
| immunological studies of tumors induced in sheep by injecting ovine cells transformed in vitro with feline sarcoma virus. | | 1975 | 183703 |
| in vitro binding of radioiodinated human follicle-stimulating hormone to reptilian and avian gonads: radioligand studies with mammalian hormones. | | 1976 | 183841 |
| orf in britain. | | 1976 | 183853 |
| concerning the independence of the basis of hypertension due to acth or renovascular constriction. | administration of acth to four sheep with chronic renovascular hypertension resulted in an increase in blood pressure which was at least as high as that described in normotensive sheep and could be completely accounted for by an increase in cardiac output. | 1976 | 183887 |
| induction of lactogenic receptors. i. in the liver of hypophysectomized female rats. | to identify the hormones which affect lactogenic receptors in the liver of chronically hypophysectomized female rats, hormones were injected s.c. for 7 days. specific binding (%, sb) of labelled ovine prolactin (prl) in liver membrane preparations (1000,000 x g pellet) of controls was 1%. estradiol (e2), cortisone (con), acth or bovine growth hormone (bgh) treatment did not induce hepatic binding sites for prl. human gh and a single dose of 2mg prl (but not lower doses) increased sb of prl. trea ... | 1976 | 183947 |
| enzymatic modification of bovine and ovine parathyrin receptor. | | 1976 | 183982 |
| [concanavalin a induced changes of lymphocyte p-nitrophenylphosphatase (author's transl)]. | the effect of k+, na+, mg2+ and atp on the p-nitrophenylphosphatase activity was investigated. as an enzyme preparation a microsomal fraction of sheep lymphocytes was used. low concentrations of mg2+, k+ and na+ increased, whereas high concentrations decreased the enzyme activity. there was an inhibition of activity by atp without na+ in the incubation medium and an increase of enzyme activity at low k:na-ratio. by concanavalin a in a concentration of 15 mug/ml the p-nitrophenylphosphatase activ ... | 1976 | 184027 |
| control of immune responses by cyclic amp and lymphocytes that adhere to histamine columns. | mixed lymphocytes from human peripheral blood, murine spleens, lymph nodes or thymus glands have pharmacologically specific receptors for histamine, beta mimetic catecholamines and prostaglandins. when these cells are exposed to the panoply of drugs mentioned above, their intracellular cyclic amp concentrations increase. the biologic consequences of such an increase were at first elusive. now we know that the immune potential of some murine spleen cells may be modulated and the release of lysoso ... | 1976 | 184034 |
| hypoglycaemia as a stimulus for adrenocorticotrophin secretion in foetal sheep. | | 1976 | 184232 |
| absence of a correlation between the secretion of adrenocorticotrophin and vasopressin in foetal sheep. | | 1976 | 184233 |
| aldosterone production by sheep adrenal glands in vitro. | | 1976 | 184350 |
| studies with bluetongue virus in nigeria. | using an agar gel diffusion test antibody evidence indicates that bluetongue virus is widely distributed in nigeria and commonly infects cattle, sheep and goats. in a single dairy herd serological conversions were observed in both wet and dry seasons. | 1976 | 184569 |
| a mucosal disease virus infection of the pregnant ewe as a cause of a border disease-like condition. | an experiment was designed to investigate whether a condition in australian sheep with clinical and pathological similarites to border disease was caused by the infection of the pregnant ewe with a mucosal disease virus (mdv). forty ewes, at 58 to 63 days after mating, were inoculated with material from lambs in which all, some or none of the tissues examined contained mdv. the clinical condition was observed only in lambs born to ewes inoculated with mdv-positive material and then only to ewes ... | 1976 | 184774 |
| endocrine and metabolic changes associated with periods of spontaneous hypoxia in fetal sheep. | periods of spontaneously occurring hypoxia have been observed in fetal sheep. these were associated with increases in the fetal plasma concentration of glucose, lactate, free fatty acids, acth and corticosteroids (for a fetus close to term). these changes are similar to those observed during experimentally induced hypoxia. hypoxia may be a mechanism by which plasma metabolites and acth are increased in fetal sheep under physiological conditions, particularly during labour. | 1976 | 184857 |
| the effect of pregnancy on mineralo- and gluco-corticoid secretion in the sheep. | 1. the peripheral blood concentrations of aldosterone, corticosterone and cortisol were measured during pregnancy in conscious, undisturbed sheep. 2. aldosterone levels did not change during pregnancy and the mean pregnant value, 1-2 s.d. 1-4 ng/100 ml(n = 12) was not significantly different from the non-pregnant value, 2-1 s.d. 1-7 (n = 16). 3. cortisol levels likewise were unchanged by pregnancy-non-pregnant values were 0-56 s.d. 0-50 mug/100 ml (n = 12) compared with 0-46 s.d. 0-40 mug/100 ml ... | 1976 | 184993 |
| serial cyclic transmission of bluetongue virus in sheep and culicoides variipennis. | bluetongue virus (strain 62-45s) was transmitted from sheep to sheep throughout a year by vector bites. a colonized population (sonora strain, 000 line) of the biological vector culicoides variipennis (coquilllett) was used. fifteen serial cyclic transmissions covered a period of 13 months from october through november of the following year. the mean infection rate of the biting gnats was 37 percent. the clinical response to bluetongue virus was significantly more severe in sheep infected by vec ... | 1976 | 185003 |
| characterization of somatogenic and lactogenic binding sites in isolated rat hepatocytes. | suspensions of rat hepatocytes isolated enzymatically by the method of berry and friend were used to study the binding of 125i-labeled human (hgh) and bovine (bgh) growth hormones and ovine prolactin (oprl). displacement of these labeled hormones by their unlabeled analogues was analyzed by means of scatchard plots and affinity constants (k) and the number of binding sites per cell (q) were calculated. specificity of binding was studied using hgh, bgh oprl and rat growth hormone (rgh) and rat pr ... | 1976 | 185044 |
| oxytocin-stimulated release of prostaglandin f2alpha from ovine endometrium in vitro: correlation with estrous cycle and oxytocin-receptor binding. | endometrial and myometrial tissues, obtained from merino ewes on 5 different days of the estrous cycle, were incubated at 37 c in 30 ml of gassed (95% o2:5% co2) krebs-bicarbonate buffer containing, 0, 10, 100 or 1,000 muu/ml oxytocin. aliquots of the medium were removed at 10 min intervals and examined for prostaglandin f2alpha (pgf2alpha) content by radioimmunoassay. fresh-frozen (-70 c) samples of endometrial and myometrial tissue were homogenized in tyrode's solution. particulate fractions f ... | 1976 | 185047 |
| analysis of human thymocyte subpopulations using discontinuous gradients of albumin: precursor lymphocytes in human thymus. | precursor lymphocytes, obtained from human tissue on bovine serum albumin (bsa) gradients followed by removal of sheep erythrocyte (e)-reactive thymocytes on ficoll, are the predominant lymphoid subpopulation found in young fetal thymuses. this subpopulation shows a progressive decline in relative numbers during fetal life, accompanied by a rise in both the relative and absolute numbers of e-reactive thymocytes. precursor thymocytes differentiate in vitro to e-reactive cells resembling t cells i ... | 1975 | 185059 |
| chirality of the hydrogen transfer to the coenzyme catalyzed by ribitol dehydrogenase from klebsiella pneumoniae and d-mannitol 1-phosphate dehydrogenase from escherichia coli. | the stereochemistry of the hydrogen transfer to nad catalyzed by ribitol dehydrogenase (ribitol:nad 2-oxidoreductase, ec 1.1.1.56) from klebsiella pneumoniae and d-mannitol-1-phosphate dehydrogenase (d-mannitol-1-phosphate:nad 2-oxidoreductase, ec 1.1.1.17) from escherichia coli was investigated. [4-3h]nad was enzymatically reduced with nonlabelled ribitol in the presence of ribitol dehydrogenase and with nonlabelled d-mannitol 1-phosphate and d-mannitol 1-phosphate dehydrogenase, respectively. ... | 1976 | 185137 |
| the assessment in sheep of an inactivated vaccine of parainfluenza 3 virus incorporating double stranded rna (brl 5907) as adjuvant. | the serological responses of conventionally reared sheep were compared after vaccination with inactivated parainfluenza 3 (pi3) virus incorporated in three different adjuvants. inactivated pi3 virus with the double-stranded rna, brl 5907 in an oil emulsion was shown to stimulate higher serum antibody titres over the first 5 weeks after vaccination than virus with and without bcg emulsified in oil. the ability of this vaccine to protect specific pathogen-free lambs against challenge with pi3 viru ... | 1976 | 185290 |
| enumeration of antigen reactive t cells against sheep erythrocytes by the virus plaque assay. | | 1976 | 185443 |
| pathogenesis of visna. i. sequential virologic, serologic, and pathologic studies. | a total of 56 icelandic sheep were infected with visna virus by intracerebral injection of strain 1514 and the course of infection was followed for 12 months. virus was isolated from more than 90 per cent of the animals, primarily from central nervous system and lymphoid tissues. however, titers of free infectious virus were minimal and virus isolation often required the use of tissue explants. all sheep raised serum-neutralizing and complement-fixing antibodies beginning 1 to 3 months after inf ... | 1976 | 185458 |
| interaction between serum factors and t lymphocytes in hodgkin's disease. use as a diagnostic test. | we studied the mechanism of defective binding of sheep erythrocytes to the surface of peripheral blood t lymphocytes (e-rosette-formation) in hodgkin's disease. the decreased percentage of e-rosette-forming cells (range, 21 to 77 per cent) in 25 patients with hodgkin's disease was reversed and returned to normal range (52 to 78 per cent) by prior incubation of the t lymphocytes in tissue-culture medium with 20 per cent fetal-calf serum for 18 to 24 hours. the percentage of e-rosette-forming cell ... | 1976 | 185517 |
| hypertensive effect of 17alpha, 20alpha-dihydroxyprogesterone and 17alpha-hydroxyprogesterone in the sheep. | | 1976 | 185522 |
| [indirect hemagglutination test for detection of antibodies to cytomegalovirus in blood collected on blotting paper (author's transl)]. | indirect hemagglutination test for detection of antibodies to cytomegalovirus is highly sensitive and reproducible, if employed in well-defined conditions. standardization of the various factors involved is necessary as well as their reciprocal equilibrium : sheep erythrocytes, antigen, dilution of tanin, buffers quality. the hemagglutination test can be performed on small volumes such as blood collection on blotting paper (pku). antibody titers were compared in the serum and the blood so collec ... | 1976 | 185575 |
| vascular angiotensin receptors and their role in blood pressure control. | the renin angiotensin system has an important role in regulating arterial blood pressure in homeostasis and disease. a reciprocal relationship exists between sodium balance and the circulating levels of renin and angiotensin ii. the vascular responsiveness to angiotensin ii, the major vasconstrictor component of the renal pressor system, can be impaired by numerous factors including sodium depletion or a reduction in effective plasma volume. in situations in which the renin-angiotensin system is ... | 1976 | 185902 |
| a mucosal disease virus as a cause of abortion hairy birth coat and unthriftiness in sheep. 1. infiction of pregnant ewes and observations on aborted foetuses and lambs dying before one week of age. | a condition resembling border disease has been transmitted by the inoculation of pregnant ewes with material from affected lambs. forty-nine merino ewes, mated to merino rams 7 to 87 days previously, were inoculated with an homogenate of brain, spinal cord and spleen from affected lambs. mummified foetuses, abortions and stillbirths were observed, and lambs with hairy birth coats were born to ewes inoculated between days 12 to 70 of gestation. a mucosal disease virus (mdv), present in the origin ... | 1976 | 185999 |
| a mucosal disease virus as a cause of abortion, hairy birth coat and unthriftiness in sheep. 2. observations on lambs surviving for longer than seven days. | a condition in australian sheep resembling border disease was transmitted by the inoculation of pregnant ewes with material from affected lambs. this material contained mucosal disease virus (mdv). twenty-two lambs comprising 6 from uninoculated control ewes, together with 11 with hairy coats and 5 with normal coats from inoculated ewes, were observed from 7 to 182 days after birth. nine of the lambs from inoculated ewes died during the experiment from a variety of causes. glial cell abnormaliti ... | 1976 | 186000 |
| membrane fluidity change in erythrocytes induced by complement system. | the structural change in erythrocyte membranes induced by antibody and complement was studied using phospholipid spin-labels. sheep erythrocytes were labeled with phosphatidylcholine spin-label and various intermediate cells (erythrocyte-antibody complex (ea), ea bound with complement components from c1 to c7 (eac1-7), eac1-8, and eac1-9) were prepared. electron spin resonance spectra of ea, eac1-7, and eac1-8 were very similar to that of the erythrocytes, while that of eac1-9 was markedly diffe ... | 1976 | 186096 |
| [electron microscopic observation of the infectious cycle of visna virus in sheep choroid plexus cells at temperatures under 37 degrees c]. | electron microscope study of viral penetration at 4 degrees c shows that viral particles first attach to cells. the attachment sites are invaginations which later fuse to form phagocytic cytoplasmic vacuoles. some virus particles with altered envelopes can be seen in the cytoplasm. after ten days of incubation at 29 degrees c, filamentous inclusions and mature viral particles are seen in the cytoplasm. the cellular membrane budding process and virus release observed at 37 degrees c have disappea ... | 1976 | 186212 |
| immunoglobulin content and antibody activity in an artificial body cavity. | artificial body cavities (abc) were created by the insertion of hollow polyethylene balls in the subcutaneous tissue of rabbits. after two months no inflammatory reaction could be detected, the abc was enveloped by a membranous structure, and the cavity contained about 20 ml of fluid. the protein concentration was about 3 times, and the igg about 8 times, lower in the abc fluids than in the corresponding serum. at the same time the antibody titers against sheep red blood cells (srbc), human igg ... | 1976 | 186399 |
| immunological monitoring and immunotherapy in carcinoma of the lung. | one hundred and seven patients with carcinoma of the lung underwent immunologic testing, and 62 of these patients were randomized to an immunotherapy protocol comparing the effects of pasteur strain bcg, either alone or combined with allogeneic tumor cells, to the effects of no immunotherapy. patients with residual disease left at the time of surgery or with metastatic disease at the time of diagnosis showed no increase in survival as a result of this form of immunotherapy. an insufficient numbe ... | 1976 | 186417 |
| experimental infection of specific pathogen-free lambs with ovine adenovirus type 4. | | 1976 | 186495 |
| experimental rotavirus infection in lambs. | | 1976 | 186496 |
| role of interferon in the pathogenesis of virus diseases in mice as demonstrated by the use of anti-interferon serum. i. rapid evolution of encephalomyocarditis virus infection. | the role of interferon in the pathogenesis of encephalomyocarditis (emc) virus infection was determined by treating mice with potent, partially purified sheep anti-mouse interferon globulin. in control mice, emc virus was present in low titers in various visceral organs but attained high titers in the brain towards the 4th to 5th day, at which time mice died with signs of central nervous system disease. in mice treated with anti-mouse interferon globulin, virus was present in high titer in visce ... | 1976 | 186554 |
| role of interferon in the pathogenesis of virus diseases in mice as demonstrated by the use of anti-interferon serum. ii. studies with herpes simplex, moloney sarcoma, vesicular stomatitis, newcastle disease, and influenza viruses. | the effect of potent sheep anti-mouse interferon globulin was investigated in several different experimental virus diseases of mice. in anti-interferon globulin-treated mice infected intraperitoneally with herpes simplex virus (hsv) type i, the latent period was shortened, and the overall ld50 was increased several hundredfold compared to virus-infected control mice. when hsv was inoculated subcutaneously all anti-interferon globulin-treated mice died, whereas only 5% of virus-infected control m ... | 1976 | 186555 |
| pathogenesis of visna. ii. effect of immunosuppression upon early central nervous system lesions. | it was hypothesized that the lesions of visna might represent an immunopathologic process. to test this hypothesis, a 1-month schedule of immunosuppressive treatment was devised, using horse anti-sheep thymocyte serum. in hampshire sheep, this regime was shown to protect against experimental allergic encephalomyelitis, to inhibit development of tuberculin hypersensitivity, to retard rejection of skin homografts by 3 weeks, and to markedly reduce the number and mitogenic responsiveness of periphe ... | 1976 | 186661 |
| pathogenesis of visna. iii. immune responses to central nervous system antigens in experimental allergic encephalomyelitis and visna. | experimental allergic encephalomyelitis (eae) was induced in sheep in pursuit of the hypothesis that an immune response against central nervous system antigens might play a role in the pathogenesis of visna. nine to 12 days after sensitization with whole sheep brain and complete freund's adjuvant, approximately 50% of sheep developed a fulminating lethal form of eae. following a second sensitization, another 20% of animals developed eae whereas a residual 30% failed to develop any signs or histo ... | 1976 | 186662 |
| experimental production of sheep pulmonary adenomatosis (jaagsiekte). | | 1976 | 186718 |
| sleep-inducing effect of a high-protein diet in sheep. | | 1976 | 186827 |
| the distribution and clearances of hormones and metabolites in the circulation of the foetal sheep. | plasma hormone and metabolite concentrations have been measured in the plasma of blood collected simultaneously from the femoral artery, umbilical vein and carotid artery of the exteriorized foetal sheep. the concentration of vasopressin and catecholamines was consistently lower and of glucose, lactate and corticosteroids consistently higher in the umbilical vein compared with the femoral artery. acth concentrations showed no consistent pattern and fluctuated widely at each site, but during syna ... | 1976 | 186838 |
| the herpesviruses. | | 1976 | 186929 |
| [specific prophylaxis of foot-and-mouth disease during summer pasturing husbandry]. | | 1976 | 186936 |