| periestrous and midluteal time courses of circulating lh, fsh, prolactin, estradiol-17 beta and progesterone in the domestic pig. | | 1981 | 6783133 |
| postmeiotic nor-expression during spermiogenesis of the domestic pig (sus scrofa domestica l.). | | 1980 | 6784408 |
| [behavioral reactions of domestic swine to odors]. | | 1981 | 6792826 |
| benzoyl peroxide and epidermal wound healing. | the effectiveness of 10%, 20%, and 50% benzoyl peroxide in a lotion, 20% benzoyl peroxide in a gel, and the effect of the vehicles alone on wound reepithelialization were evaluated in young domestic pigs. twenty percent benzoyl peroxide suspension in a lotion base substantially increased the rate of reepithelialization by 33% over a seven-day evaluation period. twenty percent benzoyl peroxide suspension in a gel base and 10% benzoyl peroxide suspension in a lotion base slightly enhanced epiderma ... | 1983 | 6824360 |
| effect of mechanical load in wound healing. | this study was designed to investigate the effect of sequentially increasing mechanical load on healing incisions. full-thickness incisions were made on the back of a young domestic pig. during the period of fibroplasia, one of the incisions was mechanically loaded with a subcutaneous tissue expander. mechanical and histological evaluations of mechanically loaded and control incision areas indicated that the mechanical stress encouraged healing and remodeling of dermal tissue. | 1983 | 6838129 |
| [comparative histometrical and histological studies of skeletal muscles in wild and domestic swine]. | | 1983 | 6847599 |
| role of adenosine in the maintenance of coronary vasodilation distal to a severe coronary artery stenosis. observations in conscious domestic swine. | the purpose of this study was to test the hypothesis that adenosine is required to maintain arteriolar vasodilation distal to a severe coronary stenosis. eight closed-chest conscious pigs were prepared by placing a 7.5-mm long stenosis (82% lumenal diameter reduction) in the proximal left anterior descending coronary artery. regional myocardial blood flow (microsphere technique) was measured at control 1, after 10 minutes of intracoronary infusion of adenosine deaminase (7-10 u/kg per min) dista ... | 1983 | 6861296 |
| assignment of superoxide dismutase (sod-1) gene to chromosome no. 9 of domestic pig. | pig--mouse somatic cell hybrids were obtained by fusing pig lymphocytes with mouse cells of the rag (hptr-) line using polyethylene glycol. the expression of pig superoxide dismutase (sod-1) activity in 11 hybrid clones as well as in the parental cells was investigated. seven hybrid clones positive for the expression of pig sod-1 displayed the corresponding parental rag and pig bands of sod-1 plus a heteropolymeric band of intermediate electrophoretic mobility. the positive and negative expressi ... | 1983 | 6883177 |
| the effect of occlusive dressings on collagen synthesis and re-epithelialization in superficial wounds. | the effects on superficial wounds in domestic pigs of (1) two different occlusive dressings, (2) non-occlusive wet to dry gauze dressings, and (3) air exposure were compared. collagen synthesis and re-epithelialization were increased in the wounds treated with occlusive dressings. re-epithelialization was increased beneath both the oxygen-impermeable and the oxygen-permeable dressing. when they were removed the wet to dry gauze dressing and one of the occlusive dressings often damaged the new ep ... | 1983 | 6887836 |
| effect of chronic guanethidine treatment on vascular norepinephrine content in the neonatal domestic pig. | vinblastine, 6-hydroxydopamine, and antibody to nerve growth factor have been shown to destroy sympathetic neurons in neonatal rats. high doses of guanethidine produce permanent sympathectomies in the adult or newborn rat. similar studies in the cat, rabbit, and hamster demonstrate that the sympathetic nervous systems are not destroyed with guanethidine. to produce permanent sympathectomy in a large animal model, guanethidine was administered to neonatal pigs. as with the cat, rabbit, and hamste ... | 1983 | 6888189 |
| ice treatment of injured ligaments: an experimental model. | using the radiocarpal ligament of the domestic pig as an experimental model the effects of ice therapy were studied. the results indicate that application of ice causes: (1) increased subcutaneous swelling to injured or uninjured soft tissue; (2) a diminution of histological evidence of inflammation in injured ligamentous tissue. | 1980 | 6928055 |
| retention of fluoride by enamel during maturation in unerupted permanent teeth of the domestic pig. | | 1980 | 6944002 |
| the interposition of lyodura in operations for ankylosis of the temporo-mandibular joint. an experimental study using pigs. | experimental investigations using domestic pigs were carried out in order to study the subject of resorption of lyophilized dura (lyodura) interposed in the region of the temporo-mandibular joint after operations for ankylosis. the condyle of the mandible was partially resected on one or both sides, the joint capsule and disc excised and the mandibular fossa stripped of cartilage. lyodura was interposed between the surfaces of the bones and intravital sequential labelling of the bones was carrie ... | 1982 | 6961178 |
| fluoride pharmacokinetics in the domestic pig. | plasma fluoride concentrations were studied in 11 pigs following single oral or intravenous doses of fluoride. the results showed a less-than-20% bioavailability of fluoride when administered with calcium-rich food. pharmacokinetic analyses showed that the plasma half-life varied from 0.6 to 1.4 h, depending on diet and route of fluoride administration. these data are comparable to those reported for man, and thus illustrate the suitability of the pig for studies of effects of fluoride on hard t ... | 1982 | 6963284 |
| a robertsonian translocation in the domestic pig (sus scrofa) 37,xx,-13,-17,t rob(13;17). | | 1982 | 6979301 |
| histological and ultrastructural studies on the pineal gland of castrated male and pregnant female of domestic pig. | | 1981 | 6981549 |
| histology and ultrastructure of the pineal gland in mature female domestic pig. | | 1981 | 6981552 |
| effects of peep and of increased frequency of ventilation during cpr. | previous reports have attributed increased carotid blood flow to lung ventilation during cpr. this study was undertaken to determine whether peep (20 torr airway pressure) or increased frequency of ventilation (3:1) improved arterial pressure, flow, and blood gases. thirty-three domestic pigs were studied using three protocols (standard 5:1 cpr, 5:1 cpr plus peep, 3:1 cpr) distributed such that comparisons could be made between groups as well as within the same pig. for intrapig comparisons, po2 ... | 1980 | 6988167 |
| biology of human skin transplanted to the nude mouse: i. response to agents which modify epidermal proliferation. | to accept human skin transplanted to the congenitally athymic (nude) mouse as a system to study human skin and its physiologic and pathologic states, it must be demonstrated that skin so maintained retains its function as a biologic unit. we have found that responses of grafted human skin and nude mouse skin to various agents differ. this difference in response has been utilized to assess barrier function and proliferative capacity of human skin grafts. human skin grafts undergo a proliferative ... | 1981 | 7017014 |
| [studies on the prevalence of corynebacterium suis in wild boars and domestic pigs in the federal republic of germany (author's transl)]. | | 1982 | 7044746 |
| the effect of the proline analogue l-azetidine-2-carboxylic acid (laca) on epidermal and dermal wound repair. | to evaluate epidermal-dermal interdependency during the wound-healing process, the proline analogue l-azetidine-2-carboxylic acid (laca) was topically applied to split-thickness skin wounds in young domestic pigs. laca is incorporated into collagen and the collagen containing this analogue is extruded from the cell at a decreased rate. wounds were assigned to one of three treatment groups: control (no treatment), laca (0.2 mg in 0.1ml of water), and placebo (0.1 ml of water). on days 2 through 1 ... | 1982 | 7054798 |
| noninvasive measurement of systolic and diastolic blood pressure in swine. | arterial blood pressure was measured noninvasively using doppler ultrasound and an occluding cuff. the subjects were 28 domestic pigs (10-49 kg) anesthetized with pentobarbital sodium (25 mg/kg). indirect pressure measurements were made with the doppler unit placed over the radial or the ulnar artery proximal to the carpal joint. comparison was made with directly measured pressure to determine the reliability and reproducibility of the indirect method. direct systolic pressures between 73 and 23 ... | 1982 | 7058906 |
| collagen fibre arrangement in the skin of the pig. | the arrangement and proportion of collagen fibres and fibre bundles in the dermis of the pig have been investigated with light microscopical (nomarski's interference contrast, polarization optics) and scanning electron microscopical methods. skin samples were obtained from different body regions of wild boars, domestic pigs and miniature pigs. all the methods used have demonstrated that the bulk of the dermis is dominated by a massive three dimensional network of collagen fibres and fibre bundle ... | 1982 | 7076540 |
| [investigations on the retention period and tolerance of hexabrix as x-ray contrast medium in arthrography (author's transl)]. | arthrography of the knee joint was performed in 12 domestic pigs using hexabrix (meglumine and sodium ioxaglate). conray ev (sodium and meglumine iothalamate) was used for comparison. x-ray films were taken at periodic intervals. hexabrix was found to stay slightly longer in the joints. the animals were sacrificed at 3 different times after injection and the synovial membrane of the knee joints and the joint cartilage of the patella were assessed histologically. 3 of 6 joints showed a strictly l ... | 1982 | 7079664 |
| fractionation and identification of pig lymph node plasma membrane glycoproteins. | plasma membrane vesicles purified from pig mesenteric lymph node tissue were solubilized in 1% (w/v) sodium deoxycholate and the fractionation of both membrane proteins and glycoproteins assessed by gel filtration on aca 34. milligram quantities of the glycoprotein fraction, consisting of 12 distinct bands on sds-page ranging in apparent mol. wt from 12,000 to 250,000, were purified by affinity chromatography on lentil lectin-sepharose. identified among these by specific immunoprecipitation were ... | 1982 | 7099163 |
| morphological studies on the epiphyseal growth plate combined with biochemical and x-ray microprobe analyses. | the epiphyseal growth plate of the domestic pig was investigated topologically combining biochemical methods with electron microprobe microanalyses both correlated to histological controls. a lateral resolution of about 50 micrometer was reached. highest nuclease activity was found in the lower columnar cell zone, while alkaline phosphatase showed maximal activity in the hypertrophic area, connected with maximal values for extractable, organically bound phosphorus, and extractable ca and mg. aci ... | 1982 | 7107329 |
| tfi transferrin variant in domestic pig. | | 1982 | 7125302 |
| the effects of antisperm plasma membrane antibodies on sperm-egg binding, penetration, and fertilization in the pig. | a procedure using published surgical techniques is described for determining the effects of antiplasma membrane antibodies on sperm-egg binding, penetration, and fertilization in vivo in the domestic pig. time of ovulation was controlled and sperm inseminated at precise times relative to ovulation. sperm were exposed to antibodies (fab) and then washed free of excess antibody and placed in one uterine horn near the uterotubal junction. sperm exposed to control material were placed in the opposit ... | 1982 | 7130938 |
| [are porous tricalcium phosphate ceramics suited for the replacement of bony walls in ear surgery? an animal experiment study of the hypotympanum of the domestic swine]. | the purpose of this study was to examine the possibility of a partially or totally posterior canal and lateral attic wall reconstruction with a more stable and therefore less porous tricalcium phosphate ceramic plate (s8). the hypotympanon of 4 pigs was drilled out, leaving the bony shell intact. in the middle part of this cavity a 2 mm thick s8-ceramic plate was placed horizontally. the hypotympanon of further 11 pigs was drilled out and obliterated with a more porous tricalcium phosphate ceram ... | 1982 | 7154802 |
| [genetic characteristics of the 1st soviet miniswine minisibs. ii. the immunogenetic characteristics of laboratory minisibs]. | a laboratory miniature siberian pig "minisibs"--a new laboratory animal in ussr is characterized by a very wide immunogenetic polymorphism for all the blood group systems studied, significantly differing in this respect from all the wild and domestic pigs. when "minisibs" were compared with american, west-german and japanese miniature pigs in relation to the blood group systems e, f, g and l, the considerable distinction was demonstrated. these immunogenetic peculiarities indicate adequately the ... | 1981 | 7197654 |
| structural studies of purified pig lymph node plasma membrane: association of cytoskeletal compounds with the plasma membrane and the effect of detergent solubilization. | the reproducibility of preparation, stability at 4 degrees c, and detergent solubilization characteristics of plasma membrane vesicles purified from domestic pig mesenteric lymph node tissue have been examined. it was found that 2% (w/v) nonidet p-40 solubilized 50-60% and 2% (w/v) sodium deoxycholate solubilized 60-70% of the total membrane protein. as judged by 125i-labelled lentil lectin staining of the sodium dodecyl sulfate--polyacrylamide gel electrophoresis patterns, 2% (w/v) nonidet p-40 ... | 1982 | 7199963 |
| structure of two subfractions of normal porcine (sus domesticus) serum low-density lipoproteins. x-ray small-angle scattering studies. | two subfractions of low-density lipoproteins (ldl) were isolated from normal pig (sus domesticus) serum by a combined method including precipitation, ultracentrifugation, and gel chromatography. the fractions recovered from the buoyant density ranges 1.020-1.050 and 1.050-1.090 g/ml, denoted as ldl1 and ldl2, respectively, were studied with regard to structure and thermotropic behavior by x-ray small-angle scattering and were compared to human serum low-density lipoprotein of density 1.020-1.063 ... | 1981 | 7248280 |
| effects of isoproterenol on the ultrastructure of pig parotid gland. | following chronic administration of isoproterenol, the parotid glands of the domestic pig were removed and studied with transmission electron microscopy. acinar cells were markedly altered, whereas ductal elements were apparently unchanged. a notable hypertrophy of golgi membranes was observed. in addition, electron-dense bodies located near the golgi membranes were more numerous after isoproterenol administration. | 1981 | 7257726 |
| [occurrence of exudative (pse) meat consistency in some domestic swine breeds]. | | 1981 | 7258021 |
| elastic fibre arrangement in the skin of the pig. | after the removal of collagen and ground substance by autoclaving tissue samples and subsequently applying the sem technique, a dense meshwork of elastic fibres could be demonstrated in the dermis of the pig (wild boar, domestic pig, miniature pig). the abdominal body region showed relatively large amounts of elastic fibres compared to the back and the lateral body wall. in comparison with the papillary layer and the mid-dermis, thicker elastic fibres predominated in the deeper dermis; thinner f ... | 1981 | 7283467 |
| lectin-induced lymphocyte stimulation in pigs--a kinetic study of nors. | early reactions of rrna-cistrons in lectin-stimulated pbl cultures of domestic pigs are shown. interphases showing 3 or more clusters of stained areas were attributed mainly to cells after first division. clear differences are shown between pha- and cona-induced nor-expression patterns compared to the patterns in pw-stimulated cultures. | 1981 | 7297648 |
| the nasal cycle in swine. | the domestic pig exhibits characteristic fluctuations in nasal mucous membrane congestion and decongestion which meet the stipulated criterion for the existence of a nasal cycle. this phenomenon was documented in 6 of the 11 pigs studied. also, unilateral sympathectomy acutely affects ipsilateral nasal resistance, but this elevated nasal resistance gradually decreases to preoperative values over several weeks. finally, a new technique using active anterior rhinomanometry has been developed which ... | 1981 | 7302471 |
| interfollicular smooth muscle in the skin of the domesticated pig (sus scrofa). | an interfollicular smooth muscle that spans the triad of hair follicles has been identified in the skin of the domesticated pig (sus scrofa). this muscle has been previously noted by other investigators and identified as an arrector pili muscle. however, it cannot be interpreted as such for the following reasons: 1) it lies opposite the arrector pili muscle on the follicle; 2) the orientation of its fibers is perpendicular to those of the arrector pili; 3) the two muscles are not continuous; the ... | 1981 | 7305026 |
| experimental atherosclerosis model in domestic pigs. part ii. electrocardiographic and morphologic investigation. | experimental atherosclerosis was produced in domestic pigs by administration for 24 weeks a high lipid diet containing cholesterol and coconut oil. ecg changes were not uniform: negative t, prolonged intraventricular conduction, and premature ventricular beats were observed. macroscopic and microscopic anatomo-pathological studies revealed atheromatous changes in the aorta. | 1981 | 7329865 |
| [histometric studies of neurons of selected nuclear regions in the hypothalamic sex centers of swine (sus scrofa domesticus) under various lighting conditions]. | | 1981 | 7337534 |
| a model of experimental atherosclerosis in pigs. part iii. electroretinography and the diameter of retinal vessels. | domestic pigs were fed with high lipid diet (hld) for 24 weeks. electroretinographic studies and the measurement of the diameter of retinal arterioles were investigated before and after the administration of hld. the most significant change produced by hld was negativization of electroretinogram. at the same time the diameter of retinal arterioles was significantly decreased. | 1981 | 7347809 |
| [picture documentation of leukemia in domestic swine]. | | 1981 | 7348921 |
| porcine (sus scrofa domestica) chromosome identification and suggested nomenclature. | various banding techniques have been used for chromosome analysis in domestic pigs (sus scrofa domestica). the techniques used in karyotype analysis were q-banding by (cma)2s, trypsin-g-banding, brdu-acridine-orange r-banding and c-banding. sequential staining techniques of quinacrine-giemsa were used to record the length of each chromosome and determine arm ratios. sequential quinacrine-giemsa-ag-as treatment was used to locate the nucleolar organizer (nor) on specific chromosomes. a g-c specif ... | 1980 | 7388680 |
| the effects of alinidine, an n-allyl derivative of clonidine, on regional myocardial perfusion and performance in the pig with or without atrial pacing. | the effects of alinidine (0.2-6.0 mg . kg-1), an n-allyl derivative of clonidine, were investigated on systemic and regional haemodynamics, in particular myocardial perfusion and performance in the domestic pig, during or in the absence of atrial pacing. the drug had a pronounced bradycardic action and also caused dose-dependent reductions in the maximum rate of rise in left ventricular pressure (max lvdp/dt) cardiac output (co), arterial blood pressure and in the mean velocity of systolic wall ... | 1980 | 7389819 |
| resting metabolism of yucatan miniature swine. | oxygen consumption, carbon dioxide production, rectal temperature and skin temperatures were measured in six conscious yucatan miniature swine. heat production was calculated from oxygen consumption and carbon dioxide production data. under ambient conditions (20 degrees c), the parameters studied were similar to what has been reported for conventional domestic swine. during 90 minutes of cold exposure (0 degrees c), oxygen consumption increased by approximately 50%. at 0 degrees c, excessive sh ... | 1980 | 7401619 |
| very low density lipoprotein metabolism in domestic pigs. | patterns of triacylglycerol (tg) turnover in plasma and liver, and the hepatic secretion of very density lipoprotein triacylglycerol (vldl tg) into the circulation, have been studied in young large white female pigs, using i.v. tracer [1,3-14c]- and [2-3h]glycerol. serial measurements were made of plasma [14c]glycerol and [14c]glucose and of liver tg and plasma vldl tg specific activities. in other studies vldl tg obtained from a donor pig was reinjected into recipient animals to measure the ear ... | 1980 | 7426088 |
| effect of water and salt intake on pituitary catecholamines in the rat and domestic pig. | | 1980 | 7432631 |
| experimental infection of warthos (phacochoerus aethiopicus) with african swine fever virus. | although there were no obvious signs of illness following experimental infection of young warthog with african swine fever virus, the animals developed viraemias between 10(2,4) and 10(3,6) hd50/ml within the first week of infection, and virus concentrations in a number of lymphatic tissues attained high levels (greater than or equal to 10(6) hd50/g). unlike in blood, and to some extent in the spleen, virus titres in lymph nodes did not decline appreciable during the 33-day observation period, s ... | 1980 | 7454231 |
| incompetence of domestic pigs as amplifying hosts of vesicular stomatitis virus for lutzomyia shannoni (diptera: psychodidae). | seven domestic pigs, sus scrofa l., were infected by intradermal inoculation at 3 different sites with the new jersey serotype of vesicular stomatitis (vsnj) virus. laboratory-reared lutzomyia shannoni dyar sand flies, a suspected biological vector of vsnj virus, were allowed to feed on pigs at the lower abdomen or at sites of their own selection on days 1-7 and on day 10 postinfection. blood samples were taken from infected swine concomitant with most feeding trials and tested for the presence ... | 1995 | 7473632 |
| renal perfusion: pharmacologic changes depicted with power doppler us in an animal model. | to evaluate the ability of power doppler ultrasonography to depict changes in renal perfusion after pharmacologic manipulations. | 1995 | 7480728 |
| sutured or fibrin-glued laparoscopic choledochojejunostomy. | minimally invasive techniques for choledochojejunostomy offer theoretical advantages for palliating unresectable periampullary neoplasms. fibrin glue, a biologic adhesive containing concentrated fibrinogen, may obviate suturing and promote healing without stricture formation. we examined the technical ability to perform laparoscopic choledochojejunostomy (lcj) and the applicability of thrombin-activated fibrin glue in an animal model of biliary obstruction. domestic pigs underwent laparoscopic c ... | 1995 | 7482208 |
| mr imaging of contrast-enhanced porcine myocardial infarction. assessment of reperfusion and tissue viability. | to assess the usefulness of dy-dtpa-bma-induced signal reduction, as an indicator of myocardial viability, myocardial infarction was induced in 17 domestic pigs by ligating a diagonal branch of the left anterior descending coronary artery (lad). in 6 pigs, dy-dtpa-bma (1 mmol/kg b.w.) was administered 4 hours after induction of ischaemia. in 5 additional pigs, gd-dtpa-bma (0.3 mmol/kg b.w.) and dy-dtpa-bma (1 mmol/kg b.w.) were simultaneously injected after 4 hours of ischaemia to ascertain whet ... | 1995 | 7484207 |
| number and distribution of silver-stained nucleolar organizer regions and evolutionary relationships in domestic pigs. | variation in the numbers of silver-stained nucleolar organizer regions (ag-nors) were examined in 36 breeds of domestic pig of different geographic origins and five subspecies of wild boar. the relationship between ag-nors and evolution of domestic pigs was investigated. in all pigs observed, ag-nors were localized on the secondary constriction of chromosomes 10 and 8. the mean ag-nor numbers varied from 2.0-4.0, and decreased gradually with the different geographical distribution from south to ... | 1995 | 7486245 |
| nuclear control of early embryonic development in domestic pigs. | in mammals, growing oocytes have characteristically high levels of rna synthesis. after the initiation of meiosis, that is germinal vesicle breakdown, this rna synthesis ceases. although there is limited evidence for rna synthesis by the zygote, significant amounts of rna synthesis do not occur until a species-specific cell stage. in pigs, significant amounts of mrna synthesis cannot be detected before the four-cell stage. there appear to be three qualitatively different periods of transcription ... | 1993 | 7511691 |
| adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts. | the efficacy of aorto-coronary vein grafting is limited by early graft thrombosis and accelerated graft atherosclerosis. direct adenovirus-mediated transfer of genes encoding inhibitory proteins may prevent or slow progression of vein graft disease. | 1994 | 7514108 |
| phylogeny of helicobacter isolates from bird and swine feces and description of helicobacter pametensis sp. nov. | previously, nine fecal isolates from wild birds and a domestic swine were identified as helicobacters by phenotypic characterization and reaction with a helicobacter genus-specific dna probe. these isolates fell into three biotypes by analysis of phenotypic traits. to further characterize these isolates, full 16s rrna sequences were determined for strains representing each biotype, and sequence comparison indicated that the strains represented three novel, phylogenetically defined helicobacter s ... | 1994 | 7520743 |
| identification of new apolipoprotein b epitopes and haplotypes and their distribution in swine populations. | results from comparative immunogenetic studies on inheritance and identification of four new apolipoprotein b (apob) allotypes and three additional apob haplotypes and their distribution in miniature and domestic swine are presented. immunological surveys on the four new and 16 previously described lpb allotypes and genetic analysis of their segregation in progenies, of miniature and domestic swine and their crosses, indicate that three new allotypes designated lpb9, lpb10 and lpb101 are individ ... | 1994 | 7524383 |
| direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors. | efficient methods of introducing genes into myocardial cells must be developed before local somatic cell gene therapy can be implemented against myocardial disease. although adenoviral (ad5) vectors have been used to target rodent hearts and plasmid dna has been directly injected into the myocardium of rats and dogs, the amounts of recombinant protein produced by these procedures have not been reported, and adenoviral vectors have not been used in large mammalian hearts. | 1994 | 7525108 |
| nitric oxide synthase in the pig autonomic nervous system in relation to the influence of ng--nitro-l-arginine on sympathetic and parasympathetic vascular control in vivo. | nitric oxide synthase, the enzyme responsible for the formation of nitric oxide, was demonstrated by an indirect immunofluorescence technique to be present in both the sympathetic and parasympathetic nervous system of the domestic pig. in the sympathetic nervous system, nitric oxide synthase was mainly present in preganglionic neurons projecting to postganglionic neurons, some of which contained neuropeptide y in the superior cervical, the coeliac and the lumbar ganglia of the sympathetic chain. ... | 1994 | 7529378 |
| effects of nk1 receptor antagonists on vasodilation induced by chemical and electrical activation of sensory c-fibre afferents in different organs. | the effects of the non-peptide nk1 receptor antagonists, cp 96,345 and rp-67,580, were investigated in a model using anaesthetized pigs. both the blood flow in the internal maxillary and the bronchial artery (ultrasonic flowmetry) and the superficial blood flow in nasal mucosa and the skin (laser-doppler flowmetry) were monitored simultaneously. vasodilation induced by substance p administered i.v. systemically was blocked by pretreatment with cp-96,345, 3 mg kg-1 but not by rp-67,580. cp-96,345 ... | 1994 | 7530891 |
| neural elements in the normal and experimentally injured porcine intervertebral disk. | there is increasing evidence that-back pain may originate from degenerated or damaged disks, even in the absence of disk herniation. for a study of the pattern of innervation in injured disks, the anterior part of the annulus fibrosus of a lumbar disk in 11 domestic pigs was incised with a scalpel through a retroperitoneal approach. the animals were killed 2 weeks, 1, 2, 3, and 5 months postoperatively, and the whole anterior annulus of each injured disk and corresponding tissue from intact anim ... | 1994 | 7532535 |
| polymerase chain reaction based genotyping for characterization of sla-dqb and sla-drb alleles in domestic pigs. | molecular genotyping of swine major histocompatibility complex sla-dqb and sla-drb genes using polymerase chain reaction (pcr)-based amplification is described. locus-specific oligonucleotide primers were designed for the analysis of expressed sla genes by reverse transcription-polymerase chain reaction (rt-pcr). rt-pcr products were sequenced, and the information gained was used to design primers for pcr genotyping of the exon 2 (beta 1) region from genomic dna templates. a single segregating a ... | 1995 | 7537478 |
| recovery from severe cyclic antidepressant overdose with hypertonic saline/dextran in a swine model. | to determine the effect of a hypertonic saline and dextran (hsd) solution on blood pressure and qs duration during severe cyclic antidepressant (ca) toxicity in swine. | 1994 | 7542551 |
| formation of the scab and the rate of epithelisation of superficial wounds in the skin of the young domestic pig. 1962. | | 1995 | 7553187 |
| localization of fragile sites in the karyotype of sus scrofa domestica: present status. | fragile sites were induced to expression in pig lymphocyte chromosomes by in vitro exposure to folate antagonists and budr-hoechst 33258. expressed fragility was localized according to the presented idiograms and compared with the location of known spontaneous translocations. | 1995 | 7558883 |
| laparoscopic assisted continent urinary diversion in the pig. | the ideal urinary reservoir would be low pressure, nonrefluxing and simple to construct. hohenfellner recently described creating an in situ ureterosigmoidostomy with a 5 to 6 cm. detubularized portion of sigmoid colon and rectum (sigmoid-rectum pouch). in an effort to further study the reconstructive applications of laparoscopy, we sought to laparoscopically create a sigmoid-rectum pouch in an animal model. in addition, we sought to compare a "dunked" (right ureter) with a hand-sewn end-to-side ... | 1995 | 7563387 |
| detection of hepatitis e virus infections among domestic swine in the kathmandu valley of nepal. | the prevalence of hepatitis e virus (hev) infections among 55 domestic swine living in the kathmandu valley of nepal was investigated. sera and stool specimens were collected from 47 free-roaming swine and examined for the presence of hev genomic sequences by the reverse transcription-polymerase chain reaction. sera from these animals, as well as sera from eight other swine, were also examined for the presence of hev-specific antibodies by an enzyme-linked immunosorbent assay and by a fluorescen ... | 1995 | 7573701 |
| [diagnosis of trichinellosis in living pigs using indirect elisa]. | a modified e/s-elisa based on the procedure described by gamble et al. (1988) was used for the diagnosis of trichinellosis in the domestic pig. the results of screening the sera of 92 pigs experimentally infected with trichinella larvae (t. spiralis, t. nativa) with different doses, confirmed that the e/s-elisa is suitable for the serological detection of trichinella-specific igg. although the serotest shows a high sensitivity especially in the case of a low infection rate, it can not be used as ... | 1995 | 7575386 |
| immunohistochemical demonstration of non-muscle myosin in the developing porcine epidermis. | using an immunohistochemical technique, the study demonstrates for the first time non-muscle myosin stress fibres in fetal mammalian epidermis, with special regard to cellular development during integumentary ontogenesis in the sparsely haired domesticated pig. the results obtained are discussed in view of possible cytoskeletal functions of the cytofilaments. | 1995 | 7577838 |
| chemical ablation of the gallbladder: is it feasible? | transcatheter ablation of the gallbladder has been attempted in animals and humans with a variety of chemical and physical agents. initial in vitro experiments suggested sodium hydroxide and hydrogen peroxide were more effective sclerosants than previously reported chemical agents. a phase i trial of escalating concentrations of and exposure times to these agents was performed in vivo. | 1995 | 7579863 |
| myocardial interstitial purine metabolites and lactate with increased work in swine. | dobutamine stimulates the beta-receptors in the heart and increases myocardial blood flow and oxygen consumption 2-3-fold, similar to effects seen with exercise. the purpose of this study was to assess temporal changes in myocardial interstitial purine metabolites, adenosine monophosphate (amp) and lactate during and following 30 min of dobutamine infusion. | 1995 | 7585825 |
| intracoronary low-dose beta-irradiation inhibits neointima formation after coronary artery balloon injury in the swine restenosis model. | neointima formation contributing to recurrent stenosis remains a major limitation of percutaneous transluminal angioplasty. endovascular low-dose gamma-irradiation has been shown to reduce intimal thickening (hyperplasia) after balloon overstretch injury in pig coronary arteries, a model of restenosis. the objective of this study was to determine whether the use of a beta-emitting radioisotope for this application would have similar effects and to examine the dose-response relations with this ap ... | 1995 | 7586273 |
| monitoring of tissue oxygenation in shock: an experimental study in pigs. | to evaluate different methods and markers for assessing adequacy of tissue oxygenation in shock. | 1995 | 7587236 |
| a new reciprocal translocation (7q+;15q-) in the domestic pig. | a reciprocal translocation was identified in a phenotypically normal large white boar. chromosome preparations from the carrier were studied by flow sorting, chromosome painting and g-banding. the flow karyotype displayed one additional clearly distinguishable peak, while in situ hybridization and g-banding showed two abnormal chromosomes involved in the translocation. all the results suggested that the translocation involved chromosomes 7 and 15 and the karyotype investigated was 38,xy,rcp(7;15 ... | 1995 | 7587395 |
| on the mechanism of skin wound "contraction": a granulation tissue "knockout" with a normal phenotype. | this report explores the mechanism of spontaneous closure of full-thickness skin wounds. the domestic pig, often used as a human analogue for skin wound repair studies, closes these wounds with kinetics similar to those in the guinea pig (mobile skin), even though the porcine dermis on the back is thick and nearly immobile. in the domestic pig, as in the guinea pig, daily full-thickness excisions of the central granulation tissue up to but not including the wound edges in both back and flank wou ... | 1995 | 7597065 |
| anastomotic diameter of circular stapled oesophagojejunal anastomoses and its implication for weight development. a clinical and experimental study. | to investigate the increase in diameter of the oesophagojejunal anastomosis after total gastrectomy with a circular stapler, and to assess experimentally the influence of oesophageal diameter on weight. | 1995 | 7599298 |
| débridement of the pig retinal pigment epithelium in vivo. | to study the morphologic effects of surgical débridement of the retinal pigment epithelium (rpe) in an animal model. | 1995 | 7605288 |
| comparative study of in vitro lipogenesis in various adipose tissues in the growing domestic pig (sus domesticus). | activities of acetyl-coa-carboxylase, malic enzyme and glucose-6-phosphate-dehydrogenase were measured in seven different anatomical sites in the growing pig (20-120 kg weight). the three enzyme activities increased up to 40-60 kg weight and then decreased, malic enzyme becoming the main producer of nadph, irrespective of the adipose tissue. subcutaneous adipose tissue of the neck area was much thicker and exhibited much lower lipogenic enzyme activities than backfat. subcutaneous adipose tissue ... | 1995 | 7613762 |
| lower esophageal sphincter pressure during prolonged cardiac arrest and resuscitation. | unprotected airway ventilation models have been based on a lower esophageal sphincter (les) pressure found in human beings under general anesthesia. whether this assumption is applicable during cardiac arrest in human beings is unknown. we attempted to determine the effects of prolonged ventricular fibrillation (vf) on the tension of the les in a swine model of cardiac arrest. | 1995 | 7618786 |
| percutaneous serial catheterization in swine: a practical approach. | in a model designed for experimental cryoablation of the his bundle in swine, a study that required multiple and follow-up cardiac catheterizations, femoral percutaneous cannulations were successfully performed in 14 of 15 swine: 6/6 yucatan miniature, 5/6 hanford miniature, and 3/3 yorkshire farm pigs, weight range 15-50 kg. a follow-up cardiac catheterization was performed in 10 of these animals: 5 hanford and 5 yucatan. femoral percutaneous cannulation was successful in 6. a cutdown approach ... | 1995 | 7619782 |
| swine model of haemophilus ducreyi infection. | haemophilus ducreyi is a strict human pathogen that causes sexually transmitted genital ulcer disease. we infected domestic swine with h. ducreyi 35000, resulting in the development of cutaneous ulcers histologically resembling human chancroid lesions. intraepidermal lesions progressed from pustules to ulcers containing polymorphonuclear leukocytes and were accompanied by a dermal inflammatory infiltrate containing t cells and macrophages. h. ducreyi was recovered from lesions up to 17 days afte ... | 1995 | 7622236 |
| chronic effects of misoprostol in combination with the nsaid, diclofenac, on gastrointestinal tract of pigs. relation to diarrheagenic activity, leukocyte infiltration, and mucosal leukotrienes. | to determine the mode of protective effects of misoprostol against the chronic gastrointestinal ulceration from the nsaid, diclofenac, studies were undertaken in domestic pigs, a model of human gastrointestinal ulceration, to determine (1) the effects of repeated daily dosing for 10 days of diclofenac 5 mg/kg/day twice a day (as voltaren tablets) on the gastrointestinal morphology, 59fe-red blood loss, mucosal myeloperoxidase (mpo) activity (as an indicator of leukocyte infiltration), and mucosa ... | 1995 | 7628265 |
| does hypoxia or hypercarbia independently affect resuscitation from cardiac arrest? | in a previous cardiopulmonary resuscitation (cpr) study in swine, ventilation was associated with improved rate of return of spontaneous circulation (rosc) compared with nonventilated animals, which had greater hypoxia and hypercarbic acidosis. we used the same model to determine the independent effect of hypoxia and hypercarbic acidosis on rosc after cardiac arrest. | 1995 | 7634893 |
| allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model. | the ability of allopurinol to protect against reperfusion injury in the heart has usually been attributed to its xanthine oxidase (xo)-inhibiting properties. human myocardium however, has exhibited low levels of xo activity. to investigate the effects of allopurinol in an xo-free model and determine whether pretreatment is necessary, 12 domestic pigs (15 kg to 20 kg) underwent occlusion of the left circumflex for 8 minutes followed by reperfusion for 4 hours. one group received allopurinol infus ... | 1995 | 7636893 |
| functional characteristics of a new coronary perfusion balloon: comparison with the flowtrack 40 in closed chest swine. | this study was designed to compare a new investigational coronary perfusion balloon (wave, scimed life systems inc.) with that of an approved, widely used, current generation device (flowtrack 40, advanced cardiovascular systems). domestic swine were anesthetized with pentobarbital and instrumented using standard percutaneous technique. left ventricular contractile function (dp/dt) was monitored using a micromanometer while intracoronary and surface ecgs were also recorded. eight target vessels ... | 1995 | 7656316 |
| mechanical ventilation may not be essential for initial cardiopulmonary resuscitation. | in a rodent model of cardiac arrest and resuscitation in which the inspired gas mixture was enriched with oxygen, resuscitability and survival were unaffected by positive pressure ventilation. in the present study, in a larger animal model, tidal volumes generated during precordial compression and with spontaneous gasping were quantitated. | 1995 | 7656640 |
| the need for ventilatory support during bystander cpr. | to compare cpr with chest compressions plus ventilatory support (cc+v) and chest compressions alone (cc). | 1995 | 7661426 |
| dysregulation of the veno-arterial response in the superior mesenteric artery during endotoxic shock. | to investigate whether the vascular dysfunction in endotoxic shock is associated with inhibition of the veno-arterial response of the superior mesenteric artery. | 1995 | 7664554 |
| dopamine-1-receptor stimulation and mucosal tissue oxygenation in the porcine jejunum. | to evaluate the effects of dopamine-1-receptor stimulation on intestinal mucosal tissue oxygenation. | 1995 | 7664559 |
| dynamics of myocardial metabolism in the preconditioned porcine heart studied using continuous microdialysis. | a microdialysis technique was used to measure myocardial catabolism of adenine nucleotides during preconditioning. following thoracotomy in domestic pigs, a probe was inserted into the ischaemic myocardium and two probes into normal myocardium. preconditioning was instituted by occluding a diagonal branch of the left anterior descending coronary artery four times over a 10 min period (interspersed with 20 min of reperfusion each time), followed by index ischaemia for 40 min and terminated by 20 ... | 1995 | 7671904 |
| mechanisms of distamycin a/dapi chromosome staining. i. competition binding effects of nonintercalative dna groove-binding agents in situ and in vitro. | the molecular mechanism underlying distamycin a-induced differential dapi fluorescent staining of metaphase chromosomes was studied in sus scrofa domestica both cytologically, using, besides dapi, two isomeric derivatives of dapi (d288.45 and d288.48), and molecularly, by in vitro competitive-binding studies using s. scrofa satellite dna and synthetic dna polymers. significant differences in heterochromatin staining were observed between d288.45 and d288.48. distinct distamycin a/dapi bands were ... | 1993 | 7678548 |
| preretinal and optic nerve head neovascularization induced by photodynamic venous thrombosis in domestic pigs. | to develop a reliable model of ischemic preretinal and optic nerve head neovascularization in young male domestic pigs. | 1993 | 7682408 |
| cholecystokinin-, enkephalin-, and substance p-like immunoreactivity in the dentate area, hippocampus, and subiculum of the domestic pig. | the distribution of cholecystokinin-like, enkephalin-like, and substance p-like immunoreactivities is described in the dentate area, hippocampus, and subiculum of the domestic pig (sus scrofa domesticus) as a baseline for future experimental studies. the distributions in the pig are compared with previous observations in other species. cholecystokinin-like immunoreactive nerve cell bodies were intensely stained and present in large numbers in all subfields studied. cholecystokinin-like immunorea ... | 1993 | 7685777 |
| sex differences in the distribution of estrogen receptors in the septal area and hypothalamus of the domestic pig (sus scrofa). | recently in the pig hypothalamus a vasopressin- and oxytocin-containing nucleus was identified which, like the supraoptic nucleus, becomes sexually dimorphic after puberty. following the increase in circulating steroids at puberty, the vasopressin- and oxytocin-containing nucleus becomes twice as large in both males and females. in adulthood, the vasopressin- and oxytocin-containing nucleus of females is approximately twice as large as that in males. because these alterations are possibly due to ... | 1995 | 7708211 |
| olfactory sensitivity to the pheromone, androstenone, is sexually dimorphic in the pig. | sexually dimorphic pheromone pathways have been used successfully to study insect olfactory coding. as one of the few mammalian species with an identified sex pheromone, the domestic pig (sus scrofa) may be an ideal vertebrate species in which to examine sex differences in olfactory processing of a specific stimulus. in this experiment, androstenone and control odor detection thresholds were measured in adult male, female, and castrated male pigs. in an operant task, pigs were tested with descen ... | 1995 | 7716200 |
| the pigmap consortium cytogenetic map of the domestic pig (sus scrofa domestica). | | 1995 | 7749224 |
| combination of vitamins c and e alters the response to coronary balloon injury in the pig. | restenosis is the major limitation of the long-term success of percutaneous transluminal coronary angioplasty. the process of restenosis involves repair of vascular injury and remodeling of vessel architecture. therapeutic interventions that improve vascular function may therefore be beneficial in the treatment of restenosis. antioxidants such as probucol and vitamins c and e have proved effective in improving endothelial function in hypercholesterolemia, inhibiting lipid accumulation in animal ... | 1995 | 7749812 |
| the pattern of coronary arteriolar bifurcations and the uniform shear hypothesis. | by minimizing the cost function, which is the sum of the friction power loss and the metabolic energy proportional to blood volume, murray derived an optimal condition for a vascular bifurcation. murray's law states that the cube of the radius of a parent vessel equals the sum of the cubes of the radii of the daughters. we tested murray's law against our data of pig's maximally vasodilated coronary arteriolar blood vessels at bifurcation points in control and hypertensive ventricles. data were o ... | 1995 | 7762878 |
| myocardial technetium-99m-teboroxime activity in acute coronary artery occlusion and reperfusion: relation to myocardial blood flow and viability. | the purpose of this study was to test the hypothesis that 99mtc-teboroxime retention within the heart depends at least in part on the presence of viable myocytes. | 1995 | 7769429 |
| effect of testosterone treatment on vasoconstrictor response of left anterior descending coronary artery in male and female pigs. | androgens may be risk factors in the pathogenesis of coronary artery disease by promoting coronary vasoconstriction. we studied the effect of testosterone treatment on coronary vascular reactivity of male and female domestic pigs treated for 2 weeks with either placebo or testosterone 10 mg/kg subcutaneous (s.c.) pellets. vascular reactivity was studied in ring segments (4-5 mm) isolated from the left anterior descending coronary artery (lad). no significant sex difference was noted in the respo ... | 1995 | 7769819 |