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plantar depigmentation in patas monkeys. 19883367361
induction of hepatitis b antibody in experimental animals by immunization with a-2 plaque virus.a sero-conversion for hepatitis b antibody has resulted from immunization of patas monkeys, guinea pigs, and rabbits with the a-2 plaque virus. this agent was isolated in tissue culture from patient sera that were positive for hepatitis b antigen. the immune response was assayed with techniques of direct and indirect counter-immunoelectrophoresis, and immune electron microscopy.19734128387
effects of changes in absolute signal level on psychophysical tuning curves in quiet and noise in patas monkeys.forward masking psychophysical tuning curves (ptcs) were measured in patas monkeys (erythrocebus patas) at 2, 4, and 8 khz at signal levels of 10, 30, and 60 db sl in quiet, and at 10 db above masked threshold in two levels of wideband noise. absolute signal levels with masking approximated those at 30 and 60 db sl in quiet. results in quiet agree with those reported in the literature, demonstrating broadening of the ptc as signal level is increased. the ptcs measured in noise also demonstrated ...19873624642
loa loa: development and course of patency in experimentally-infected primates.loa loa infections were studied in baboons, rhesus and patas monkeys. animals were infected either by s.c. injection of third-stage larvae (l 3) or by surgical implantation of juvenile worms of known age, sex and number. microfilaremia was first detected in baboons at 140 days following inoculation of l 3 and at 142 days and 143 days in patas and rhesus monkeys, respectively; the mean prepatent period was 151 days in baboons, 149 days in patas monkeys and 169 days in rhesus monkeys. the primary ...19853867108
passive joint mobility in patas monkeys (erythrocebus patas): rehabilitation of caged animals after release into a free-ranging environment.a previous study of passive joint mobility in patas monkeys (erythrocebus patas) showed that laboratory-caged animals had significantly greater mobility in most joints than age/sex matched free-ranging monkeys. passive joint mobility on 27 of the same animals was measured 6 months after the caged animals were released onto a 40-hectare island. the results show that within 6 months of becoming free-ranging, typical passive joint mobility is restored. thus, although caging directly affects measure ...19854061570
use of 99mtc-sulfur colloid to assess lymphatic dysfunction in filarial infection.investigations of lymphatic dysfunction in animals infected with filarial parasites has been hampered by a paucity of techniques to measure efficiency of lymphatic drainage. in this study a 99mtc-sulfur colloid technique was used to assess the efficiency of lymphatic drainage in patas monkeys infected with filarial nematodes. in all 15 uninfected hind limbs there was rapid and consistent appearance of labeled colloid in the primary lymph node (popliteal) and subsequently in the secondary nodes ( ...19854095602
interspecies scaling of the pharmacokinetics of n-nitrosodimethylamine.the pharmacokinetics of n-nitrosodimethylamine was studied in patas monkeys following i.v. doses of 0.5, 1.0, and 5.0 mg/kg and a p.o. dose of 1.0 mg/kg, and in swiss mice at i.v. doses of 1.0 and 2.0 mg/kg. in the patas monkey the pharmacokinetics was linear over the i.v. dose range studied. the mean clearance (cl), steady-state volume of distribution (vss), mean residence time, and elimination half-life (t 1/2) were 103.3 +/- 26.7 (sd) ml/min, 3061 +/- 821 ml, 30.8 +/- 10.8 min, and 21.1 +/- 8 ...19902364390
[pseudotuberculosis in red long-tailed monkeys (erythrocebus patas patas)]. 19724627826
sedation of sheep and patas monkeys with ketamine. 19744204194
fibrinopeptides a and b of japanese monkey (macaca fuscata) and patas monkey (erythrocebus patas): their amino acid sequences, restricted mutations, and a molecular phylogeny for macaques, guenons, and baboons.amino acid sequences of fibrinopeptides a and b from the macaque, macaca fuscata (japanese monkey) and the guenon, erythrocebus patas (patas monkey) were established. fibrinopeptides a of the monkeys had a sequence identical with those of baboons: ala-asp-thr-gly-glu-gly-asp-phe-leu-ala-glu-gly-gly-gly-val-arg. fibrinopeptides b were 9-residue, "short," peptides with the sequences asn-glu-glu-ser-leu-phe-ser-gly-arg for m. fuscata and asn-glu-glu-val-leu-phe-gly-gly-arg for e. patas. the sequenc ...19853928610
early immunoglobulin formation and hemagglutinating and bactericidal titers in erythrocebus patas after oral adminstration of a weakly pathogenic shigella strain. 19684174914
pregnancy, birth and early infant behaviour in the captive patas monkey erythrocebus patas. 19654953765
hand preferences and dexterities of captive patas monkeys. 19664955690
serological responses of patas monkeys (erythrocebus patas) to vaccination against cholera and yellow fever. 19734196722
social interactions in a group of captive patas monkeys (erythrocebus patas). 19674961906
a comparison of rk-13, vervet monkey kidney and patas monkey kidney cell cultures for the isolation of rubella virus. 19674964173
gallbladder damage and prolonged excretion of cholera vibrios in erythrocebus patas. 19684967028
intestinal absorption of d-xylose and folic acid in protein-deficient patas monkeys (erythrocebus patas). 19744206324
[habituation of the vertex point in 2 african monkeys, erythrocebus patas and cercopithecus aethiops]. 19694238896
susceptibility of patas monkeys to re-infection with infectious hepatitis. 19694979896
adrenal cortical rests of the ovarian hilus of the patas monkey. 19694981451
in vitro and in vivo studies of streptomycin-dependent cholera vibrios.streptomycin-dependent cholera vibrio strains were derived from inaba, ogawa, and nag vibrios by the method of mel. these phenotypes grew more slowly and attacked fermentable substances after a longer period of time than the streptomycin-sensitive parent strains. rabbits injected with streptomycin-sensitive strains and their streptomycin-dependent forms showed homologous agglutinin production. patas monkeys fed with 10(9) streptomycin-dependent strains shed them for 1 to 2 days without ill effec ...19704985829
endocrine profile of pregnancy in the patas monkey (erythrocebus patas).spontaneous toxemia occurs in approximately 6% of pregnancies in patas monkeys (erythrocebus patas). to assess further the relevance of this animal as a model system for toxemia of pregnancy in humans, we characterized the endocrine profile of the patas pregnancy by analyzing weekly blood samples for estrone, estradiol, estriol, progesterone, aldosterone, and pra throughout gestation. the profiles obtained bear striking resemblance to those described for human pregnancy, an unexpected finding si ...19853882395
relationship of age and serum immunoglobulins to antoantibodies against brain constituents in primates. ii. response of erythrocebus patas to shigella dysenteriae 1 exotoxin. 19724633135
differences among isolates of simian hemorrhagic fever (shf) virus.simian hemorrhagic fever (shf) virus is a member of the togaviridae family which currently is unclassified to genus. we have studied the relatedness of four different shf virus isolates obtained from infected macaque or patas monkeys. differences were found among isolates in type and severity of disease produced in patas monkeys, cell sensitivity to infection, viral antigens, and levels of specific antibody induced in patas monkeys. based on these criteria, the four isolates have been grouped in ...19863945613
studies of the delta herpesvirus isolated from the patas monkey (erythrocebus patas). 19714329230
further studies on the transmission of the agent of infectious hepatitis to patas monkeys. 19695775298
serologic study by enzyme-linked immunosorbent assay of the igm antibody response in the patas monkey following experimental simian varicella virus infection.the time course of igm and igg antibody appearance in sera following experimental simian varicella virus infection in the patas monkey was studied. serum igm and igg antibody to delta herpes virus (dhv) were measured by a double indirect and indirect elisa test, respectively. igm antibody was detected 5-8 days postinfection (p.i.) and igg antibody was present 10-14 days p.i., which was 5-7 days after igm. viremia preceded detectable igm antibody by 2 days. sucrose gradient separation of serum ig ...19846094088
elimination of persistent simian hemorrhagic fever (shf) virus infection in patas monkeys.devastating epizootics of simian hemorrhagic fever (shf) have been iatrogenically initiated in captive colonies of macaque monkeys by strains of shf virus emanating from asymptomatic persistently infected patas monkeys. we have found that persistently infected patas monkeys can be cleared of their infection by superinfection with strains of shf virus which cause acute infections in this species. all 20 persistently infected animals subjected to this procedure have been cleared of their infection ...19863945628
hormone-releasing silastic intrauterine devices: effect or provera-releasing intrauterine devices on two species of primates.silastic intrauterine contraceptive devices (iuds) 13 mm long and 1.07 mm in diameter could be inserted easily into patas monkey uteri which, like human uteri, expelled them. addition of 10% provera to these devices did not reduce the expulsion rate significantly in our study. control devices had no effect on cycle length in rhesus monkeys. after insertion, the active iuds frequently caused a delay in onset of menstruation; however, cycles did occur with the device in situ, and normal-length cyc ...19751171027
naturally occurring yersinia enterocolitica septicemia in patas monkeys (erythrocebus patas).two cases of yersinia enterocolitica septicemia occurred in a breeding group of 22 adult patas monkeys (erythrocebus patas). affected animals had acute clinical signs of depression, weakness, dehydration, hypothermia, hepatomegaly and pronounced leukopenia. both animals died a few hours after treatment was initiated. gross necropsy findings included jaundice, fluid in body cavities, hepatomegaly, splenomegaly, multiple white foci within the liver and spleen, generalized lymph node enlargement an ...19854057942
ecological aspects of the jos plateau, nigeria.the jos plateau has an area of about 6 700 km(2), lies at 1 280 m above sea level, and contains approximately 1 million inhabitants. annual rainfall averaged 137 cm in the period 1965-68; in 1969 rainfall totalled 170 cm and lasted for a month longer than usual.the rural population is engaged in agriculture, tin mining, and cattle grazing. animal life consists chiefly of domestic species; there are few large wild animals. wild primates are apparently rare, although baboons and red patas monkeys ...19724538036
psorergatic mites in patas monkeys. 19724334428
cocaine potentiates the disruptive effects of phencyclidine on repeated acquisition in monkeys.patas monkeys acquired a different four-response chain each session by responding sequentially on three keys in the presence of four geometric forms. the response chain was maintained by food presentation under a fixed-ratio schedule. errors produced a brief timeout but did not reset the chain. each day there were four 15-min sessions, with a 10-min intersession interval. cumulative dose-effect curves for phencyclidine were obtained by giving an im injection before each of the four sessions; suc ...19854080768
oral immunization with polyvalent streptomycin-dependent escherichia coli vaccine.streptomycin-dependent escherichia coli serotypes o 111, o 55 and o 26 were used to vaccinate young patas monkeys against these organisms by the oral route. five administrations of 10(10) cells in 3-day intervals gave almost full protection to the animals against challenge with 9 to 11 minimal infective doses of homologous virulent organisms for at least 1 month, whether the three serotypes were administered singly or simultaneously.19724623276
[ultrastructure of medullary granulocytes in patas monkeys: periodic structures in neurophilic and basophilic granules]. 19714340382
evaluation in nonhuman primates: evaluation of the physical dependence capacities of oripavine-thebaine partial agonists in patas monkeys. 19734211992
pathology and clinical history of delta herpesvirus infection in patas monkeys. 19744360748
exanthematous disease in patas monkeys caused by a herpes virus. 19684175746
experiences with a new test of exocrine pancreatic function in protein deficient patas monkeys. 19744216958
[electron microscopic studies of kidney cells of erythrocebus patas after infection with sv 40 and adenovirus type 12]. 19704193497
changes in facial color associated with pregnancy in patas monkeys. (with 1 color plate). 19744218575
pulmonary arterial pressure and structure in the patas monkey after prolonged administration of aminorex fumarate. 19734632967
relationship of age and serum immunoglobulins to antoantibodies against brain constituents in primates. i. a study in apparently healthy man, macaca mulatta and erythrocebus patas. 19724633134
osseous hydatidosis in a patas monkey. 19744426869
placenta previa in a patas monkey (erythrocebus patas). 19714993828
susceptibility of erythrocebus patas monkeys to rubella virus. 19694996477
pulmonary arterial pressure and structure in the patas monkey (erythrocebus patas patas). 19705500132
diarrhea in nonhuman primates: a survey of primate colonies for incidence rates and clinical opinion.veterinary clinicians associated with 18 colonies of nonhuman primates were surveyed for their experience with diarrhea disease in colony animals for calendar year 1981. the 1981 diarrhea incidence rate, diarrhea-specific mortality rate and diarrhea case fatality rate for 13,385 monkeys were 10.6%, 1.2% and 11.1%, respectively. it was not possible to incriminate age or type of housing as risk factors for diarrhea, but some species seemed at greater risk than others. erythrocebus patas monkeys ha ...19846513506
mycobacterium bovis infection in primates in dublin zoo: epidemiological aspects and implications for management.an outbreak of tuberculosis in non-human primates was successfully contained in the isolation area of dublin zoo. a mayotte lemur, a lion-tailed macaque, a patas monkey and a siamang gibbon developed tuberculosis, and mycobacterium bovis was isolated from all but the lemur, from which lesions were not cultured. procedures for the prevention of tuberculosis in primate collections and for the management of outbreaks are discussed. the need for typing of the isolated pathogen is emphasized.19846392739
recovery from monocular deprivation in the monkey. i. reversal of physiological effects in the visual cortex.this is a study of the effects of monocular deprivation, reverse suturing (opening the deprived eye with closure of the other) and reopening of the deprived eye alone (without closing the other) on the physiological organization of the primary visual cortex in monkeys (erythrocebus patas). all animals were initially monocularly deprived by suture of the lids of the right eye from soon after birth until about 4 weeks of age (24-29 days). in a monocularly deprived animal, recordings were taken fro ...19816119688
recovery from monocular deprivation in the monkey. ii. reversal of morphological effects in the lateral geniculate nucleus.the cross-sectional area was measured of neurons in the lateral geniculate nucleus (l.g.n.) of monkeys (erythrocebus patas) subjected to monocular deprivation by unilateral eyelid suture, and of others in which the closed lids had been subsequently opened (either alone, "reopening', or together with closure of the previously open eye, "reverse suture'). monocular deprivation for the first month of the monkey's life retards l.g.n. cell growth such that neurons in the laminae innervated by the clo ...19816119689
recovery from monocular deprivation in the monkey. iii. reversal of anatomical effects in the visual cortex.transneuronal autoradiography was used to study the effects of visual deprivation on the ocular dominance stripes in layer ivc of the striated cortex of erythrocebus patas (old world) monkeys. the animals were studied after: (a) 21-28 days of monocular deprivation starting at, or within, a few days of birth; (b) the same treatment followed by a further 3, 6, 15 or 126 days of monocular vision through both eyes (reopening). one other monkey was monocularly deprived from birth to 1890 days. in mos ...19816119690
kinetics of virus-specific igg and igm antibody response in patas monkeys experimentally infected with delta herpesvirus by enzyme-linked immunosorbent assay.the kinetics of virus-specific igg and igm antibody response in patas monkeys experimentally infected with delta herpesvirus (dhv), was studied using enzyme-linked immunosorbent assay (elisa). an indirect elisa (ie) test was used for dhv igg determination, whereas a "double sandwich" (triple antibody layer) elisa (dse) test was found to be very sensitive for dhv igm detection. in dse test dhv igg appeared to interfere with igm determination only in sera containing dhv igg levels at least 100 tim ...19846096678
ineffectiveness of adenine arabinoside and adenine arabinoside 5'-monophosphate in simian varicella infection.adenine arabinoside and adenine arabinoside 5'-monophosphate (ara-amp) have been evaluated for antiviral activity against simian varicella virus infection in monkeys. in a preliminary study for toxicity, intramuscular injection of ara-amp at 15 mg/kg per day as a single injection for 5 days to two normal patas monkeys caused no detectable local reaction, no weight loss or changes in serum transaminase levels, and no hematological abnormalities. when this dose was given in the treatment of four s ...19806158291
gross structure and function of the quadriceps femoris in lemur fulvus: an analysis based on telemetered electromyography.analysis based on telemetered electromyography from the quadriceps femoris of lemur fulvus, a malagasy prosimian, during walking, galloping, leaping, and a variety of postural behaviors partially confirms and partially contradicts earlier hypothesized functions of this musculoskeletal complex. as predicted on the basis of morphological criteria (large physiological cross-section and long parallel fibers), the vastus lateralis is of special functional significance in leaping. this relatively larg ...19806771412
simian haemorrhagic fever (shf): new virus isolate from a chronically infected patas monkey.a new strain of simian haemorrhagic fever (shf) virus was isolated from chronically infected patas monkey no. 248 (p-248) in usu-104 cells. the p-248 isolate had the same size, morphology and cytoplasmic site of replication as the prototype lvr strain. however, the p-248 isolate caused a persistent infection without noticeable cytopathology in usu-104 cells rather than the strongly lytic infection produced by prototype lvr virus. the capacity of p-248 virus to produce a persistent, non-lytic inf ...19806161999
studies on norgestrel-releasing intrauterine devices in erythrocebus patas monkeys. 19816114061
antibody responses to experimental brugia malayi infections in patas and rhesus monkeys.humoral antibody responses in experimental infections with brugia malayi (subperiodic strain) were compared in two primate species. erythrocebus patas and macaca mulatta. antibody responses were related to the infection protocol and the duration and magnitude of microfilaremia. patas monkeys were uniformly susceptible to infection and characteristically exhibited prolonged microfilaremia; infections in rhesus monkeys produced low and usually microfilaremia. antibody, measured by enzyme linked im ...19836134454
method to detect asymptomatic carriers of simian hemorrhagic fever virus.evidence was obtained that mononuclear phagocytic cells are the target cells for simian hemorrhagic fever virus replication. using peritoneal macrophages from rhesus monkeys in an in vitro, 18 of 20 asymptomatic chronically infected patas monkeys were detected from coded samples. the two chronically infected patas monkeys not detected by the test, nevertheless, contained virus. this was determined by inoculating macrophage cultures with plasma from macaques dying as a result of inoculation with ...19806257971
fatal herpesvirus infection in patas monkeys and a black and white colobus monkey.fatal herpesvirus infections were diagnosed in 3 patas monkeys and 1 black and white colobus monkey over a 4-week period. herpesvirus was isolated from 1 patas monkey and from the black and white colobus monkey. both isolates had growth characteristics similar to herpesvirus hominis and herpesvirus simiae. the isolate from the colobus monkey antigenically appeared to be h simiae or h simiae-like, whereas the isolate from the patas monkey could not be conclusively identified with the antisera use ...19816276349
simian varicella virus (delta herpesvirus) infection of patas monkeys leading to pneumonia and encephalitis. 19826278510
serological investigation of an outbreak of simian varicella in erythrocebus patas monkeys.an epizootic of simian varicella occurring in a colony of erythrocebus patas monkeys was studied serologically by using radioimmunoassay and neutralization tests against (i) a virus strain isolated from an animal that died during the epizootic, (ii) a simian varicella virus strain from an earlier outbreak of simian varicella-like disease at another facility, and (iii) human varicella-zoster virus. serological tests detected more cases of infection among the animals exposed to virus during the ep ...19836313751
density gradient characterization of the high density lipoproteins in cholesterol-fed hyper- and hyporesponding patas monkeys (erythrocebus patas).diet-induced changes in high density lipoprotein (hdl) density and size were studied in patas monkeys. when the animals were switched from a moderate fat-low cholesterol diet to a high fat-high cholesterol (hfhc) diet, the plasma apoa-i levels increased initially in all of the animals. the apoa-i levels remained elevated in monkeys able to maintain their plasma cholesterol concentrations near basal levels (hyporesponders), but began to decrease in monkeys who became severely hypercholesterolemic ...19846436420
[on the variability of the skinfold system of long-tailed monkeys (cercopithecus) and hussar monkeys (erythrocebus patas)]. 19684970567
the distribution of serum high density lipoprotein subfractions in non-human primates.the ultracentrifugal flotation patterns in 1.2 g/ml solvent and ultracentrifugal gradient distribution of high density lipoproteins (hdl) from the primates--human, apes and monkeys--were determined, with emphasis on the gorilla species of apes and rhesus monkeys. diets for non-human primates were commercial chow, which is low in cholesterol. molecular weights and protein, cholesterol, phospholipid and triglyceride compositions of various density fractions were determined on human, gorilla and rh ...19846438429
presumed super-foetation in an erythrocebus patas monkey. 19694979459
detection of g-c rich heterochromatin by 5-azacytidine in mammals.a new effect of 5-acr (5-azacytidine), observed in fibroblast or kidney cell cultures is described in the calf (bos taurus) and in some selected primates (cebus capucinus, erythrocebus patas, and cercopithecus cephus). this cytidine analogue, used at low doses during the last late s phase, prevents the condensation of r-band positive heterochromatin (g-c rich segments). thus, 5-acr treatment can be used as a simple method for the detection of g-c rich heterochromatin.19816164628
development of a nonhuman primate model for fetoscopy.twenty-four fetoscopy procedures were performed on 22 monkeys (19 macaca mulatta, one m. fascicularis, two erythrocebus patas) with gestational ages ranging from 66 to 145 days. insertion of the fetoscope without ultrasound guidance was easy in 14 and difficult in ten procedures. amniotic fluid exchange with normal saline, to improve visualization, was successful in eight of 13 procedures. fetal blood sampling was successful in four of nine attempts. nine monkeys aborted within 17 days of the fe ...19836209400
behavior of vervet monkeys and other cercopithecines. new data show structural uniformities in the gestures of semiarboreal and terrestrial cercopithecines.a comparison of the communicative gestures of vervets with those of other cercopithecines reveals both similarities and differences. examples have been given of gestures (i) exhibited by all cercopithecines, (ii) rare or absent in vervets and common in several other species, (iii) demonstrated by vervets and a few other cercopithecines, and (iv) common in vervets and rare or absent in other members of the subfamily. vervets, baboons, and rhesus monkeys have approximately the same number of visua ...19674960943
thermoregulation in erythrocebus patas: a thermal balance study.a thermal balance study over an ambient temperature (ta) range of 15-40 degrees c was performed on six nonacclimated patas monkeys (erythrocebus patas) weighing between 3.9 and 6.0 kg. o2 consumption, co2 production, mean weighted skin temperature (tsk), rectal temperature (tre), respiratory evaporative water loss (eresp), and total evaporative water loss (etot) were measured continuously after equilibration at each ta. tsk increased as ta increased, whereas tre was maintained between 37.6 and 3 ...19836643195
phencyclidine in combination with pentobarbital: supra-additive effects on complex operant behavior in pigeons.pigeons acquired a different four-response chain each session by responding sequentially on three keys in the presence of four colors. the response chain was maintained by food presentation under a fixed-ratio schedule. errors produced a brief timeout but did not reset the chain. when phencyclidine was administered alone, the overall response rate decreased and the percent errors increased with increasing doses. similar effects were found with a high dose of pentobarbital alone. when phencyclidi ...19827134244
blood values of free-ranging patas monkeys (erythrocebus patas).free-ranging patas monkeys (erythrocebus patas) from el guayacán island, puerto rico, were surveyed to establish values for the hemogram, serum biochemicals, calcium, and phosphorus. results were tabulated for males and nonpregnant/nonlactating, pregnant, and lactating females. a summary of blood values from previous studies on captive patas monkeys was also tabulated for comparison.19836680146
antibody response of patas monkeys to experimental infection with delta herpesvirus. 19846723641
experimental disseminated strongyloidiasis in erythrocebus patas. i. pathology.fatal disseminated disease was induced in ten patas monkeys infected with two southeast asian strains of strongyloides stercoralis. while some animals died within 6 weeks after infection, others controlled their infections until placed on high doses of corticosteroids. larvae were first noted in the stools 11-20 days after transcutaneous exposure to filariform larvae. daily larval counts tended to increase as the infections progressed, but the number of larvae in the stool was not predictive of ...19846731675
experimental disseminated strongyloidiasis in erythrocebus patas. ii. immunology.parasite-specific humoral and cellular immune responses were evaluated in seven erythrocebus patas monkeys experimentally infected with a southeast asian strain of strongyloides stercoralis. most animals developed high titers of anti-larval surface igg antibody (as evaluated by the indirect immunofluorescence test), and all animals tested developed specific ige antibody (as shown by the in vitro histamine release test). modest lymphoproliferative responses to s. stercoralis antigens were demonst ...19846731676
in vivo and in vitro characteristics of eccrine sweating in patas and rhesus monkeys.biopsy specimens from the chest, palm, back, and lateral calf were obtained from three patas (4-6 kg) and two rhesus monkeys (6 and 8 kg) tranquilized with ketamine hydrochloride (10 mg/kg). the eccrine sweat glands of the specimens were subsequently isolated under a stereomicroscope and prepared for analysis. in both palmar and hairy skin (chest, lateral calf) patas eccrine glands were larger than those isolated from corresponding sites obtained from the rhesus specimens. in vitro stimulation o ...19826749777
domestic breeding of patas monkeys (erythrocebus patas).two reproductive strategies were used in the management of a patas monkey (erythrocebus patas) breeding colony. the first strategy involved placement of all animals into one-male harem units for breeding, parturition, and infant rearing. the second strategy involved a reduction in the number of males, movement of pregnant females to individual cages, and formation of new groups with females and neonates. the second strategy resulted in an increased percentage of females having successful births ...19817311469
studies on vaccination against bacillary dysentery. 5. studies in erythrocebus patas.in earlier studies in man it has been demonstrated that streptomycin-dependent shigellae, if given orally in 5 sufficiently large doses, confer a very high type-specific protection against bacillary dysentery.in the present study, 2 groups of erythrocebus patas monkeys were immunized with live streptomycin-dependent shigella flexneri 2a, and a third group was not vaccinated. one of the vaccinated groups was given streptomycin with each dose of the live vaccine. the animals that received streptom ...19704993182
interferon prophylaxis against simian varicella in erythrocebus patas monkeys.erythrocebus patas monkeys were given placebo or human leukocyte interferon (5 x 10(5) units/kg of body weight per day im) for five days during an epizootic of simian varicella. during the 14 days beginning with the first day of treatment, the attack rate for simian varicella was 14.3% (two of 14) among interferon recipients compared to 70% (nine of 13) among placebo recipients (p less than 0.025). excluding animals with antibody to simian varicella when the study began, 18% (two) of 11 interfer ...19836296238
differential effects of phencyclidine and mda on complex operant behavior in monkeys.in one component of a multiple schedule, patas monkeys acquired a different four-response chain each session by responding sequentially on three keys in the presence of four geometric forms (learning). in the other component, the four-response chain was the same each session (performance). the response chain in each component was maintained by food presentation under a fixed-ratio schedule. errors produced a brief timeout but did not reset the chain. with increasing doses of phencyclidine the ov ...19846494215
the disposition of a novel tetrahydroquinoline, tiquinamide, in rats and patas monkeys.the absorption of tiquinamide occurred rapidly and extensively in both rats and patas monkeys. the major site of localization of radioactivity was in the stomach in both species. tiquinamide was 50-60% bound to rat plasma and 50-75% to monkey plasma. the elimination of unchanged drug from plasma took place rapidly, with half lives of 1.6 h in rats and 0.7 h in monkeys. elimination of total radioactivity in the rat was very slow and monoexponential, with a half-life of 90 h. however, in the monke ...19827173271
phencyclidine in combination with pentobarbital: supra-additive effects on complex operant behavior in patas monkeys.in one component of a multiple schedule, patas monkeys acquired a different four-response chain each session by responding sequentially on three keys in the presence of four geometric forms (learning). in the other component, the four-response chain was the same each session (performance). the response chain in each component was maintained by food presentation under a fixed-ratio schedule. errors produced a brief timeout but did not reset the chain. when administered alone, phencyclidine and pe ...19827058207
social organization in a group of free-ranging patas monkeys.a free-ranging group of patas monkeys (erythrocebus patas) was studied at the caribbean primate research center through parts of a complete seasonal cycle. analysis of the data revealed that dispersal was the major strategy utilized by individuals in the performance of intragroup social behavior. dominance phenomena were not found to be of major importance in the organization of intragroup social behavior despite the presence of a linear, stable dominance hierarchy among the adult females. the d ...19807216002
phencyclidine in combination with d-amphetamine: differential effects on acquisition and performance of response chains in monkeys.in one component of a multiple schedule, patas monkeys acquired a different four-response chain each session by responding sequentially on three keys in the presence of four geometric forms (learning). in the other component, the four-response chain was the same each session (performance). the response chain in each component was maintained by food presentation under a fixed-ratio schedule. errors produced a brief timeout but did not reset the chain. when phencyclidine was administered alone, ov ...19846728878
acyclovir treatment of experimental simian varicella infection of monkeys.replication of simian varicella virus (svv) in vero cell cultures was inhibited by acyclovir, 9-(2-hydroxyethoxymethyl)guanine (acv), at a concentration of 10 micrograms/ml in culture medium. intravenous administration of acv at 10 mg/kg twice a day for 10 days or 15 mg/kg three times a day for 5 days to patas monkeys (erythrocebus patas) beginning 48 h after svv inoculation blocked the appearance of rash and other clinical symptoms but did not affect viremia. acv treatment of african green monk ...19817305319
studies on the biotransformation of indoramin in the patas monkey.1. studies on absorption, excretion and biotransformation of the antihypertensive agent indoramin (3-[2-(4-benzamidopiperidino)ethyl]indole hydrochloride) have been carried out in patas monkeys. 2. absorption of the drug was extensive, as indicated by less than 8% of the dose appearing in faeces as the unchanged compound. 3. approx. 35% of an orally administered dose of the 3h-labelled drug was recovered in urine while a similar amount was found in faeces. urinary excretion of total 3h was mono- ...19817336756
multinodular splenic abnormality in a red patas monkey. 19827090159
atherosclerosis in the erythrocebus patas, an old world monkey.fifty monkeys of the species erythrocebus patas were fed a control monkey chow, a semi-synthetic diet containing 25% lard, or a semisynthetic diet containing 25% lard and 0.5% cholesterol for 2 years. the patas monkeys had naturally occurring atherosclerosis that was greatly accelerated by feeding a diet containing cholesterol. the atherosclerosis involved the aorta, predominantly the abdominal portion, the coronary arteries, and various peripheral vessels. histologically, the atherosclerosis wa ...19806766672
[schistosoma mansoni experimental schistosomiasis in erythrocebus patas monkeys (author's transl)].a number of erythrocebus patas monkeys have been experimentally infected only once, with schistosoma mansoni local strain. the various parasitological, biological and immunological observations show that e. patas is a very adequate host to schistosoma mansoni and that it develops an intestinal schistosomiasis parasitologically very close to human schistosomiasis. it is noted that in this case of single infection e. patas reactions are the same as the other species generally used in the experimen ...19806772918
ultrastructure of experimental coronary artery atherosclerosis in cynomolgus macaques. a comparison with the lesions of other primates.we studied the ultrastructure of the left anterior descending coronary artery in 6 female cynomolgus macaques fed atherogenic food containing 0.5% cholesterol for 6 months, and in 2 female cynomolgus macaques that had received food low in cholesterol. animals given the atherogenic food had coronary artery lesions of a characteristic two-level architecture consisting of a lipid-poor upper cap, and of a lipid-rich lower core. the cap consisted of layers of smooth muscle cells that were rich in rou ...19827115459
complement components c3, c4, and bf in six nonhuman primate species.the extent of cross reactivity between antisera to human complement proteins [the third (c3) and fourth (c4) components and factor b (bf)] and these proteins in the sera of six species of nonhuman primates was examined. strong cross reactivity was found with these antisera and the specific complement proteins from rhesus monkeys, stumptailed macaques, cynomolgus macaques, patas monkeys, african green monkeys, and squirrel monkeys. although molecular differences were apparent as indicated by diff ...19826804713
dopamine and temperature regulation in the primate: effects of apomorphine and pimozide.the purpose of this study was to determine the effects of a specific dopamine-receptor agonist (apomorphine) and antagonist (pimozide) on temperature regulation in the primate. using 4 rhesus monkeys and 2 patas monkeys as subjects, increasing doses of apomorphine (0.05, 0.1, 0.2, 0.4, 0.6 mg/kg) injected subcutaneously produced a dose-dependent hypothermia associated with sharp elevations in tail-skin and ear pinna temperatures. apomorphine also produced dose-related behavioral responses includ ...19807407631
a system for the continuous collection of 14co2 from patas monkeys: the metabolism of [14c]cloguanamile.1. an apparatus is described that allows co2 expired by monkeys to be trapped and measured and urine and faeces to be separated and collected. 2. when [14c]cloguanamile was administered to rats and to patas monkeys, a marked species difference was seen in the proportion of 14co2 expired. 3. suppression of the gut flora by neomycin revealed that this difference was due to enterofloral metabolism.19816805138
seroepidemiologic, molecular, and phylogenetic analyses of simian t-cell leukemia viruses (stlv-i) from various naturally infected monkey species from central and western africa.a study of simian t-cell lymphoma/leukemia virus infection, conducted on 747 nonhuman primates belonging to 14 different species in central and western africa, indicated that 4 species (cercopithecus aethiops, erythrocebus patas, papio doguera, and cercopithecus mona pogonias) had a high prevalence of seropositivity to simian t-cell lymphoma/leukemia virus type i (stlv-i). the other nonhuman primate species, however, had negative or low levels of anti-htlv-i antibodies. stlv-i pol and env dna wa ...19948259665
fluorescence of experimental atheromatous plaques with hematoporphyrin derivative.fluorescence of hematoporphyrin derivative (hpd) has been used clinically to localize malignant neoplasms because of its selective accumulation in these tissues. we tested the hypothesis that hpd may also be selectively concentrated within atheromatous plaques. 48 h after hpd injection in a variety of species, selective fluorescence of atheromatous plaques of the aorta was seen in each animal (rabbits and patas monkey) exhibiting such lesions. no fluorescence could be demonstrated in aortic segm ...19836822671
studies on the metabolism of the new anti-hypertensive agent, indoramin, in man.the absorption, metabolism and excretion of the new antihypertensive agent indoramin (baratol) have been studied in male volunteers following oral administration of the drug labelled either with 14c or with tritium. absorption of the drug proceeded at moderate rate, peak plasma radioactivity levels being seen by 3 h after dosing. metabolism was extensive as shown by very little unchanged compound appearing in urine. two major urinary metabolites accounting for some 35-40% of the renally excreted ...19836873141
campylobacter jejuni isolated from patas monkeys with diarrhea.campylobacter jejuni was isolated from 11 (46%) of 24 patas monkeys with chronic diarrhea. eight of these 11 (73%) monkey were characterized clinically by mucohemorrhagic diarrhea for periods up to a month followed by loose, semi-formed feces for a 12-month period. half of the monkeys were treated with erythromycin for 10 days and the other half with tetracycline for 10 days, with all responding to treatment. despite treatment, all monkeys again had an outbreak of mucohemorrhagic diarrhea. biops ...19836876739
influence of age, sex, and caging on joint mobility in the patas monkey (erythrocebus patas).normal range of joint mobility in the extremities of the patas monkey, erythrocebus patas, was established for a free-ranging colony of 64 animals at la parguera, puerto rico (caribbean primate research center). eighty-five animals that had been caged (30" x 30" cages) for up to 5 years were used for comparison. passive joint mobility of anesthetized animals was measured with a goniometer. nine parameters (five on the forelimb and four on the hindlimb) were measured on each animal. the data were ...19836881323
[electrophoretic polymorphism in erythrocebus patas].variations were observed at the prealbumin-2, carbonic anhydrase-i, 6-phosphogluconate dehydrogenase, phosphoglucomutase-ii and adenylate kinase loci in erythrocebus patas subspecies pyrrhonotus. but the level of heterozygosity was very low compared with those of the different african monkey species studied by the same electrophoretic analysis. the reasons for this low variation are discussed with regard to ethological and genetic structure characteristics of the group studied.19836884907
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