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the influence of ph on equilibrium effects of tetrodotoxin on myelinated nerve fibres of rana esculenta.1. the experiments were done on single nodes of ranvier of rana esculenta. the effects of tetrodotoxin and h ions were determined either by the reduction of the maximum rate of rise, va, of action potentials evoked with threshold stimuli or in the voltage clamp by the decrease of the peak na permeability, pna. 2. with the tetrodotoxin sample used throughout the investigation the equilibrium dissociation constant, kt, of the toxin-receptor reaction at neutral ph was determined to be 2-8 nm. betwe ...1975492
the influence of ph on the rate of tetrodotoxin action on myelinated nerve fibres.1. the experiments were done on single myelinated nerve fibres of rana esculenta. the rates of toxin effect were studied either by measuring the maximum rate of rise, va, of repetitively evoked action potentials or by measuring na currents during periodic impulses in the voltage clamp. 2. va measurements showed that in alkaline solutions (ph up to 8-8) the offset rate was unchanged while the onset was slowed in quantitative agreement with an assumed decrease in the active cationic form of tetrod ...1975493
[control of pituitary secretion of melanotropin in an anuran amphibian by thyrotropin releasing factor (trh). study in vitro].intermediate lobes from rana esculenta pituitary glands were continuously superfused for 7 hrs at 28 degrees c with amphibian culture medium. alpha-msh release was measured by use of a sensitive double antibody radio-immunoassay system. alpha-msh secretion was inhibited by low temperatures. a large increase in alpha-msh release was observed when thyrotropin releasing hormone (trh) at doses ranging from 10(-9) to 10(-7) molar was added to the superfusion medium. since large amounts of trh are to ...197716704
the stimulation of na+ uptake in frog skin by uranyl ions.1. the na+ uptake in the isolated from skin of rana esculenta was measured by the short-circuit current (isc). uranyl ions increase at ph 5.5 the isc up to 200% at concentrations of 10 mm. the half-maximal value for this effect is at about 1 mm uranyl salt. 2. the effect is (a) specific for the na+-selective membrane, (b) fully reversible. no stimulation can be seen in presence of 1 mm h+ or 0.1 mm amiloride. 3. the decrease of the sodium permeability of the apical membrane (pna), normally induc ...197826398
rates of block by procaine and benzocaine and the procaine-benzocaine interaction at the node of ranvier.1. action potentials and their maximum rates of rise, va, were measured in single myelinated nerve fibres of the frog, rana esculenta at room temperature. 2. on applying 1 mm procaine (ph 7.2) at 20 hz stimulus frequency, half of the final va reduction was reached at ton = 0.27 s; on applying 0.5 mm benzocaine (ph 7,2) at 50 hz, ton was 0.12 s. increasing the stimulus frequency between 2 and 50 hz increased the rate of block by procaine but not by benzocaine. 3. recovery in ringer solution (ph 7 ...197830940
acid phosphatase from liver of the frog rana esculenta, separation and partial characterization of multiple forms.1. acid phosphatase (acpase) from liver of the frog, rana esculenta has been isolated and purified. the enzyme is heterogeneous, showing 4 activity zones on disc electrophoresis. the acpase was separated into 3 peaks on deae-cellulose. peak a corresponding to the electrophoretic acpase iv represents an extensively purified enzyme form. 2. the separated enzyme forms are change isomers with a molecular weight of about 33,000. they differ markedly in substrate requirements and sensitivity towards a ...197835912
the mode of action of phenobarbital on the excitable membrane of the node of ranvier.single myelinated nerve fibres of rana esculenta were investigated under current and potential clamp conditions at 20 degrees c. under 2.5 mm phenobarbital, the amplitude of the action potential was reversibly reduced to 85.5 +/- 5% (n = 6), and the threshold potential was raised by 32% of the control in ringer solution. the resting potential remained constant. solutions with 2.5 mm phenobarbital caused a decrease of the na current to 38.3 +/- 5.6% (n = 10), when the fibre had its holding potent ...197938130
isolated sympathetic ganglion from rana esculenta and its pharmacologic reactivity. 197938625
partial purification and some properties of a liver alkaline ribonuclease from the frog rana esculenta.1. rnaases varying in ph optimum, activation with pcmb, sensitivity towards temperature and acid treatment, as well as electrophoretic mobility were found in rana esculenta liver extract. 2. of the three activity peaks of alkaline ribonuclease separated on cm-cellulose with 2000-fold purification, rnaase of peak c is thermo- and acid-stable and exhibits specificity for pyrimidine bases, preferring poly(u) over poly(c). 3. differences in the specific "inhibitory effect" of frog liver supernatant ...197940372
effects of ph on k depolarization and contracture in frog muscles.membrane potential changes and mechanical tension provoked by 20 or 80 mm k at ph 8.0 or 4.5 were measured in muscle fiber bundles from rana temporaria and rana esculenta. the bathing solution contained cl as the main anion. low ph increased the depolarizing efficiency of high k to about the same degree in muscles of both species of frogs. the tension-[k] relationship was shifted toward lower [k] in muscles from r. temporaria and toward higher [k] in muscles from r. esculenta. it was concluded t ...197944689
the effect of mammalian gonadotropins and homologous gonadotropins on the activity of delta 5-3 beta-hydroxy-steroid-dehydrogenase (hsd) in hypophysectomized rana esculenta.mammalian gonadotropins and partially purified gonadotropins (fsh and lh) from an amphibian (rana esculenta) were used to investigate their action on enzymatic activity of delta 5-3 beta-hsd in male and female hypophysectomized rana esculenta in stage of genital activity (october) and in stasis or hibernation stage (january). amphibian and equine lh stimulate delta 5-3 beta-hsd activity especially in females hypophysectomized in the stage of genital activity, while ovine fsh action is very low a ...197945831
the function of fat bodies in relation to the hypothalamo-hypophyseal-gonadal axis in the frog, rana esculenta.in this study the authors have tried to furnish experimental support for the importance of fat bodies in the normal functioning of the hypothalamo-hypophyseal-gonadal system of the male frog, rana esculenta. these experiments have shown a hypothalamo-hypophyseal control of the mobilization of fat body contents, directly involved in the control of testicular activity. furthermore it is proposed that the fat body contents are released into the testis through direct vascular contacts between the tw ...197551684
preparation of specific antiserum against rana esculenta pre-alpha lens crystallin.specific antiserum against rana esculenta lens pre-alpha crystallin was prepared in a rabbit by injecting antigen-antibody precipitate of this crystallin obtained from immunoelectrophoresis of esculenta total soluble lens proteins against homologous antiserum.197660253
gomori-positive cells in the telencephalon of rana esculenta l. during the annual cycle. 197769559
a comparative cytochemical study of the yolk platelets in the growing oocytes of triturus cristatus and rana esculenta.recent cytochemical techniques for the detection of proteins, neutral and acid mucopolysaccharides, lipids and phospholipids in the yolk platelets of the growing oocytes of rana esculenta and triturus vulgaris are employed. cytochemical analysis showed that the yolk in the form of granules or platelets, in the constituting itself the most prominent cytoplasmic inclusion of amphibian eggs, contains a protein moiety consisting of individual typical amino acids lacking tryptophan in triturus, a car ...197773338
macrophage disappearance reaction in rana esculenta induced by specific antigen and rabbit lymphokines.macrophage disappearance reaction was induced by intraperitoneal injections of specific antigens in rana esculenta sensitized by bovine gamma globulin and mycobacterium bovis bcg. rabbit lymphokines derived from concanavalin a stimulated blood lymphocytes injected intraperitoneally were able to induce macrophage disappearance reaction in normal rana esculenta. this suggests that mammalian lymphokines are capable of acting in amphibia. mammalian lymphokines have not an exclusive class-specificity ...197773345
the delayed outward current compared in the heart of the frog (rana esculenta) and the tortoise (testudo germani) [proceedings]. 197880180
regulation of the annual cycle of the oviduct of rana esculenta. effects of inhibition of rna synthesis on the recovery phase. 201594947
[primary visual centers in the frog (rana esculenta l.) and the problem of ipsilateral projections. radioautographic study].the topographic organization of the frog's primary visual system has been reexamined in rana esculenta using autoradiographic technique. 10 to 24 hrs following an intraocular injection of tritiated proline, an intense labelling was observed contralaterally in the various retinal projection centres (preoptic area); neuropils of bellonci; corpus geniculatum of the thalamus; posterior thalamus; posterodorsal preoptic area; magnocellular pretectal nucleus and basal optic nucleus; tectal laminae a to ...1978100235
[topography of the tecto-tectal component of the main ipsilateral visual pathway of the frog (rana esculenta l.)].the detailed topography of the tecto-tectal component of the frog's ipsilateral visual pathway is electrophysiologically obtained by mapping the optic lobes. this linkage transfers the visual information explored along a transversal tectal row on to an homologous line oriented at 130 degrees on the opposite tectum. the ipsilateral projection of the temporo-nasal axis of the retina, but not of the antero-posterior axis of the visual field, is reversed compared to its contralateral projection. fin ...1998110480
[distribution of thyrotropin releasing hormone (trh), alpha-melanocyte-stimulating hormone (alpha-msh) and somatostatin in the skin of the green frog (rana esculenta)].high concentrations of thyrotrophin-releasing hormone (trh) have been found in the dorsal skin of the frog rana esculenta, lower levels being measured in the ventral skin. alpha-msh and somatostatin were undetectable in these tissues. nor was trh detected in the blood of these animals. the concentration of somatostatin in the pancreas was similar to that of the hypothalamus and twice or one hundred times higher than in the intestine or stomach respectively.1979111817
[existence of a non-retinotopic contralateral retino-tectal visual projection in the normal frog rana esculenta l].in the frog, after unilateral optic nerve and tract section, contralateral visual responses were recorded in the tectum ipsilateral to the section. these responses were elicited by stimulation of a unique spatial region located near the projection of the contralateral eye optic axis and could be randomly recorded on the tectal surface. the possible pathways and the role of such retino-tectal afferences are discussed.1978114313
[double central projection of viiith cranial nerve in the frog (rana esculenta l.)].in the frog we have cut the anterior or the posterior root of the viiith nerve between scarpa's ganglion and the medulla oblongata. the degenerations show that both roots project onto the ventral and the dorsal vestibular nuclei.2002126728
[effect of some antibiotics on semi-circular canal activity in the frog (rana esculenta)].we have studied the action of two ototoxic antibiotics (streptomycin and gentamycin) on the activity of the horizontal semicircular canal in comparison with those of penicillin and 7 g/1 nacl solution, all of them being injected into the labyrinthic cavity. only streptomycin and gentamycin have a specific action, and the one of streptomycin is much more important than the one of gentamycin.2002126733
histochemical studies on the tongue of anuran amphibian: i. mucopolysaccharide histochemistry of the papillae and the lingual glands in hyla arborea l., rana esculenta l. and bufo vulgaris laur. 2002128314
[response of efferent vestibular fibers to horizontal rotation in frogs (rana esculenta l.)].the activity of efferent vestibular fibres has been recorded on the nerve of the left vertical anterior semicircular canal detached from its ampulla during rotations in the horizontal plane. different types of responses have been found; they are noted in table i and pictured on fig. 2.1975129239
[involution of gonadotrophic cells of the pituitary gland in the male frog, rana esculenta, after section of the pituitary stem].one and two months after section of the hypophyseal stalk in the male frog. rana esculenta, and involution of numerous gonadotrophic cells, contrasting with the normal aspect of the eosinophilic cells can be observed.1976137054
[interpretation of the cross sectional structure of skeletal muscle fibers. 2. light and electron microscopic studies of m. rectus abdominis in rana esculenta].in both longitudinal and cross sections of rectus abdominis muscle of rana esculenta three types of muscle fibres are identified by means of light and electron microscopy. a comparison is made between these fibre types in homologous muscles of frog and mammals (rat and mouse). in longitudinal sections of mammalian and frog muscle the z-line can be used for discrimination of the fibre types a, b and c because that line is of different thickness in each type. the proportions of the thickness in fr ...1975137606
seasonal variation in the active transporting ability and in the membrane atpase activity of the frog intestinal epithelium.the active sugar and amino acid transport in the small intestine of the american leopard frog (rana pipiens) and a species of european frog (rana esculenta) decreases during the winter months. parallel with this the (na+, k+)-stimulated ("pump") atpase activity is markedly depressed. no seasonal changes are observed in the intestine of the tropical bullfrog (rana catesbeiana). it is assumed that the low pump-atpase activity is caused by the hibernation of the frogs living in moderate or subtropi ...2000139926
a chemical analysis of rana esculenta egg jelly envelope. 1977146997
electron microscopic localization of mg2+ -dependent adenosine triphosphatase activity in the amphibian pancreas (salamandra salamandra l. and rana esculenta l.).the ultrastructural distribution of mg2+ -dependent adenosine triphosphatase (atpase) activity has been investigated in the salamander and frog pancreas by using glutaraldehyde fixations and a modified wachstein-meisel reaction medium. in both species the reaction product (lead phosphate) was found associated with the plasma membrane external side of all islet cell types (b-, a- and d-cells) and of acinar and ductular/centro-acinar cells. except the apical pole of salamander acinar and centro-ac ...1978153700
[functional significance of stilling cells in the interrenal glands of rana esculenta l]. 2003166007
a radioimmunoassay for plasma corticotropin in frogs (rana esculenta l.). 2003166008
cyclic changes in the enzyme activity of the hypothalamo-hypophyseal system of the frog, rana esculenta. 2003166012
[radioimmunologic assay of plasma corticotropin in the green frog, rana esculenta l].in the green frog (rana esculenta) the plasma contains a polypeptide immunologically related to human and porcine corticotropins. a radiommunoassay capable of detecting 4.10-12 g hog acth has been used for a direct plasma acth assay in the frog. using this method, the acth rate was determined both in untreated frogs and in animals under various experimental conditions.1975167995
appearance of sex hormone receptors in frog (rana esculenta) tadpole skin during metamorphosis.in tadpole skin of rana esculenta, a specific testosterone receptor was detected during the climax in both males and females. the kass ranged between 1 and 2.79 x 10(9)m-1.2003169146
differentiation of photoreceptors in cultured optic vesicles from embryos of rana esculenta.optic vesicles from embryos of rana esculenta at a stage corresponding to stage 19 in the development of rana pipiens were cultured for 15 days. the eyes which differentiated in vitro were much smaller than controls of the same age, due partly to the absence of the vitreous body. in many specimens a well-stratified retina surrounded by a layer of pigmented cells was found. the features of all the components of the retinal layers are described. the complete differentiation of photoreceptors, incl ...1975170356
[effects of adh, cyclic amp and theophylline on the permeability of the bladder to urea in rana esculenta]. 1976181039
regulation of the aldosterone secretion in the frog rana esculenta l. 2003181288
[role of various regulation factors of interrenal gland activity in response to stress in the green frog rana esculenta l].the effects of an ether stress on the corticosterone levels were studied in variously experimented frogs. the removal of the distal lobe of the pituitary gland, with preservation of the intermediate lobe which contains also acth, suppresses, as total hypophysectomy, the increase of corticosterone level observed in normal frogs. the administration of dexamethasone reduces but not suppresses this increase. a second ether stress 20 minutes after the first is effective. the injection of frog plasma ...1976183874
[a new bioassay for amphibian corticotropin using isolated interrenal cells of the frog rana esculenta l (author's transl) (proceedings)]. 2016193428
changes in corticotropin producing cells in the pituitary of rana esculenta l. following interrenalectomy and metopirone treatment. an immunohistochemical study. 2003193762
[effect of cyclic amp and theophylline on the permeability of urea across the urinary bladder of rana esculenta]. 1977199213
post-synaptic potentials recorded from afferent nerve fibres of the posterior semicircular canal in the frog.glass microelectrode recordings were made from single fibres of the posterior ampullary nerve in the isolated labyrinth of the frog (rana esculenta). potentials were recorded both at rest and during rotatory stimulation of the canal. at rest, the tracings revealed an intense background of small, largely summated potentials (0.5-10 mv amplitude, 3-6 msec duration), which underlay the discharge of spikes in all the impaled units. the frequency of the subthreshold events was related to the frequenc ...1977199319
an electron microscope observation of the right and the two left portions of the habenular nuclei of the frog.the right dorsal habenula (rdh), the left dorsal habenula, lateral portion (ldh-lp) and the left dorsal habenula, medial portion (ldh-mp) of the adult frog rana esculenta have been studied by the electron microscope with the use of three types of fixatives: osmium tetroxide, aldehydes and potassium permangarate. the study has demonstrated in the habenulae of both sides a variety of syraptic vesicles, special synaptic patterns (en passant, serial, axo-somatic) containing small spherical transpare ...1977199623
fine structural localization of glucose-6-phosphatase activity in the pancreatic islets of two amphibian species (salamandra salamandra l. and rana esculenta l.).the ultrastructural distribution of glucose-6-phosphatase activity has been investigated in the salamander and frog pancreas. in the pancreas of salamander the enzyme was located in the a-cells, while in frog it occurred in all main types of islet cells b-, a-, and d-cells). as a rule, the reaction intensity was higher in the frog islet cells. no reaction was recorded in the exocrine pancreatic tissue of both species. the glucose-6-phosphatase activity was constantly detected in the lumen of rou ...1977201137
thyrotropin-releasing hormone does not alter the release of melanocyte-stimulating hormone or adrenocorticotropic hormone from the rat pars intermedia.thyrotropin-releasing hormone (trh) has been reported to stimulate the release of melanocyte-stimulating hormone (msh) from the pars intermedia (pi) of rana esculenta. to test its effect on the rat pi, acutely dispersed rat pi cells, as well as whole nervosa-intermedias (ni), were incubated with synthetic trh, from 10(--10)--10(--4)m. trh did not alter the release of either msh or adrenocorticotropic hormone (acth).1977204881
immunoreactive melanocyte-stimulating hormone (alpha-msh) in the brain of the frog (rana esculenta l.). 1978206484
dual effect of external calcium on the frequency of miniature synaptic potentials in frog sympathetic ganglion cells.the effect of calcium on spontaneous transmitter release and on the release induced by tetanic stimulation and by raising the external potassium concentration ([k]0) was studied in sympathetic ganglion cells of rana esculenta. 1. in standard ringer's solution the frequency of miniature excitatory postsynaptic potentials (mepsp) ranged from 0.05--2.0 s-1 (0.05 +/- 0.09 s-1, n = 37) at room temperature. 2. at a [k]0 of 2.5 mm mepsp frequency was approximately linearly related to the logarithm of t ...1978212708
does lateral specialization apply to the frog's brain? an electron microscope observation.the ultrastructure of polymorphic crystal-like inclusions occurring in the cytoplasm of neurons of only the medial portion of the left habenula has been studied in the adult frog rana esculenta and in the tadpole with the use of three types of fixatives: osmium tetroxide, a mixture of aldehydes and potassium permanganate.1977214968
research on cholesterol, steroidal hormones and liposoluble vitamins by thin layer chromatography in some adipose organs of anuran amphibians. ii. liposoluble vitamins.by means of thin layer chromatography and selective detection, vitamin a acetate, vitamin e and vitamin e acetate, vitamin d3 and cholesterol were identified in the prepericardic body, adrenal tissue, fat bodies and testis of bubo bufo, as well as in the prepericardic body of rana esculenta. on the contrary, liposoluble vitamins could not be isolated from the adipose tissue occurring in the thoracic cavity of rana esculenta, or in bufo bufo muscles. the results are discussed in correlation with ...1976218524
in vivo na+- and cl minus-independent transport across the skin of rana esculenta.the relationship between the trans-epithelial na+ and cl minus absorptions from dilute external solutions and the h+ and base excretions were studied in rana esculenta in vivo. the following results relate to transport from na2so4 solutions: 1) the na+ absorbed is exchanged against endogenous h+. 2) diamox injection (1.10-4 m-kg-1) simultaneously inhibits both na+ absorption and h+ excretion. 3) the addition of amiloride to the external medium (final concn: 5-10-5 m) inhibits na+ absorption and ...1975234692
interactions between the redox state of the biophase and the effect of acetylcholine on the activity of (na+ / k+) atp-ase in rana esculenta. 1991240628
the rates of saxitoxin action and of saxitoxin-tetrodotoxin interaction at the node of ranvier.voltage clamp experiments were done on single nodes of ranvier of rana esculenta. equilibrium effects were obtained from ina-v curves, the rates of action from changes in ina on changing solutions during repetitive depolarizing pulses. 2. saxitoxin (stx) exclusively and reversibly blocked na channels, the effect being fully described by a one-to-one reaction between stx and a receptor at the channel with an equilibrium dissociation constant, ks, of 1.4 nm; the mean offset rate constant k2s, was ...1975241053
effect of harmaline on sodium transport in rana esculenta skin.1 harmaline, together with certain hallucinogenic alkaloids of the same group (harmine, 2 methyl harmin) stimulates sodium transport across the in vitro skin of rana esculenta when it is added to the external medium at a low concentration (0.1 mm). this effect is due to an increase of the sodium influx, and is reversed by washing. it is suggested that harmaline intervenes at the sodium penetration sites at the external face of the transport compartment. 2 at a higher concentration (5 mm) added t ...1977300035
the interpeduncular nucleus (itp). ultrastructure data indicative of a possible neurosecretory activity.special types of cells of the interpeduncular nucleus (itp) in the fog, rana esculenta, are described after three typed of fixation: osmium tetroxide, aldehydes and potassium permanganate. large granules with a sub-unit structure occurring together with bundles of filaments and elongated mitochondria are illustrated in the processes of cells, the perikarya of which lie distant from the ependymal lining of the aqueduct of sylvius. such processes cross the itp in a dorso-ventral direction perpendi ...1977300043
active hydrogen excretion and sodium absorption through isolated frog skin.the in vitro skin of rana esculenta was studied in open-circuit conditions. it was shown that when the external face is bathed in a 2-meq solution of nacl, sodium is absorbed at a significantly higher rate than chloride. the ionic balance is maintained by excretion of hydrogen. with a mucosal solution of 2 meq na2so4 the equation relating sodium absorption to proton excretion is jnh+ = (-25 +/- 7) - (0.73 +/- 0.04) jnna+. the correlation between the two variables is highly significant. hydrogen ...1977301706
[competitive protein-binding radioassay of corticosterone in the plasma of the frog, rana esculenta l. (author's transl)].1. plasma corticosterone levels were measured in the plasma of the edible frog, rana esculenta, by a competitive protein-binding radioassay method using baboon plasma as cbg source. 2. this technique was sensitive enough to make the assessment of corticosterone levels in 50 microliter plasma samples possible. the assay sensitivity threshold reached 0.5 ng per tube and the corticosterone rate assessment was correct between 0 and 5 ng. the specificity was tested, using 12 different steroids (fig. ...1975301934
[functional relationships between the horizontal and vertical anterior semicircular canals in the labyrinth of the frog (rana esculenta l.)].we have studied the vestibular postrotatory reactions (reactions elicited by the stimulation of the horizontal semicircular canals) in the frog blinded by section of optic nerves, before and after section of the ampullary nerves of the vertical anterior semicircular canals (vac). 90 frogs have been studied. in 30 frogs the ampullary nerves of the two vac have been cut; in 60 animals either the ampullary nerve of the right vac or of the left vac has been cut. both after section of the ampullary n ...2006302081
[seasonal changes of skin- and liver-melanin contents in rana esculenta l]. 1994303112
[changes in the melanin content in the kupffer cells of rana esculenta l., induced by parenteral administration of heme]. 1994303113
[reconstruction of the crystalline lens from fragments of capsular membrane and epithelium in larvae of rana esculenta]. 1977303423
fever and behavioural temperature regulation in the frog rana esculenta.the skin and colonic temperatures were recorded in frogs (rana esculenta) which had selected a suitable microenvironment in a box filled with 2-3 cm water. the water temperatures ranged from 0 degrees c to + 40 degrees c. such measurements were performed before and after intraperitoneal injections of killed pathogenic bacteria (m. xenopi and m. range), killed non-pathogenic bacteria (m. aquae ii) and 0.9% sterile saline, intraperitoneal injections of blood plasma from frogs pre-injected with kil ...2004303438
biochemical variation in the rana esculenta complex: a new hybrid form related to rana perezi and rana ridibunda.investigations of the green frogs from western europe for electrophoretic variations at 4 enzyme loci demonstrated a new form which must be considered as a hybrid between rana ridibunda and r. perezi. biochemical evidence supports the hypothesis that its reproduction is hybridogenetic, as it is for r. esculenta.1977304017
the under-corrected lens of the frog eye (rana esculenta) could yield comparable aerial and underwater vision. 1977304271
influence of lithium upon the intracellular potential of frog skin epithelium.the effect of li upon the intracellular potential of frog skin (rana esculenta) was investigated. in the range between 1 and 25 mm li in the epithelial bathing solution, a semilogarithmic linear relationship between [li] and intracellular potential under short circuit conditions was obtained. the intracellular potential at all [li] is quantitatively sufficient to explain the previously reported accumulation of li in the intracellular space of the frog skin epithelium (leblanc, g. 1972. pfluegers ...1977304486
influence of the saccule, lagena and vertical posterior canal on the ipsilateral horizontal and vertical anterior semicircular canals in rana esculenta: role of receptor-receptor fibres.the influence of the efferent vestibular system being eliminated, the spontaneous activity of single afferent fibres of the ampullary nerves of the horizontal and vertical anterior semicircular canals was recorded in the frog. by stimulating electrically the nerves of the vertical posterior canal, lagena or saccule as well as by sectioning these nerves and then using statistical methods, it is shown that the receptor-receptor fibres arising from the above mentioned receptors have generally an in ...1977304559
[effect of luminal "hyperosmolarity" on the permeability of the isolated rana esculenta colon]. 1977304729
a comparative study of physiological and structural changes at the myoneural junction in two species of frog after transection of the motor nerve.structural and functional behaviour of motor end-plates after transection of the motor nerve has been studied in two species of frog: rana esculenta and rana temporaria. the physiological results show that in both species there is a transient cessation of spontaneous activity followed by a resumption of miniature end-plate potentials (min. e.p.p.s.) after denervation. the characteristics of these potentials (frequency, distribution of amplitudes, time-course) are similar in the two species. howe ...1977304765
influence of changes in composition of the cerebrospinal fluid on the secretory activity of the subcommissural organ in rana esculenta. a quantitative histochemical and autoradiographic study by means of scanning cytophotometry.the effects of injection into the brain ventricle of noradrenaline dissolved in amphibian ringer's solution, and of amphibian ringer's solution alone on the secretory activity of the subcommissural organ (sco) of rana esculenta were studied. the parameters used were: the amount and mean concentration of secretory material within the sco stained by aldehyde fuchsin (af), the amount and mean concentration of radioactive material within the sco labelled by 35s-cysteine, and the growth rate of the r ...1987304766
influence of temperature and gonadal steroids on the testis composition in rana esculenta. 1978304814
coupling between chloride absorption and base excretion in isolated skin of rana esculenta.the net excretory fluxes of base (hco3- or oh-) and the unidirectional fluxes of chloride were measured and their relationship examined in isolated frog skin maintained in open- or short-circuit (oc and sc) conditions. when the mucosal solution was a 2 mm choline chloride solution and the serosal solution a ringer solution buffered with a hco3-/co2 mixture, the rate of base excretion was -105 +/- 10 in oc and -60 +/- 7 neq h-1 cm-2 in sc. a highly significant correlation was observed between the ...1978307916
asymmetrical displacement currents in the membrane of frog myelinated nerve: early time course and effects of membrane potential.1. asymmetrical displacement currents were studied in myelinated nerve fibres from rana esculenta with a voltage clamp technique. 2. for brief pulses symmetrical with respect to a holding potential of--97mv, the asymmetry current flowing during pulses (on-response) exhibited a rising phase to a peak followed by an approximately exponential decline. after the pulses the rising phase in the off-response could not be resolved; the time constant varied about 2-fold with either size or duration of th ...1978308219
cole-moore effect in the frog node.potassium currents were recorded from the voltage-clamped frog node (rana esculenta) during various test pulses that followed hyperpolarizing prepulses of different amplitudes and durations. both the delay in potassium current onset and the shape of the current trace as a function of time were found to be a function of prepulse parameters. this finding is different from the current trace superposition described by cole and moore for a specific test pulse, sodium equilibrium potential in the squi ...1978308232
[effect of sits (4-acetamido-4'-isothycocyano-2,2'-disulfonic-stilbene) and of acetazolamide on the spontaneous potential of the gastric mucosa of rana esculenta]. 1978308370
model of skin vascularization in rana esculenta l.: scanning electron microscopy of microcorrosion casts.microcorrosion casts of blood vessels in the skin of rana esculenta l. were examined by means of scanning electron microscopy with particular reference to the subepidermal network of respiratory capillaries. due to the fact that arteries and veins lie in the deeper layers of the stratum spongiosum of the corium, the respiratory vessels form a morphologically homogeneous network. functionally, however, this network is subdivided into small areas with a centripetal direction of blood flow. the dee ...1978308395
[morphological and physiological characterization of fiber types in the iliofibular muscle of rana esculenta].in both longitudinal and cross sections of the m. iliofibularis of rana esculenta three types of muscle fibres are identified by means of light and electron microscopy. these fibretypes called a-, b- and c-fibres are according to the fibres of m. rectus abdominis of the frog. they can be compared with the fibres of the m. rectus abdominis of rat and mouse. but there is another distribution of the fibretypes a, b and c in the m. iliofibularis and in the m. rectus abdominis. the m. iliofibularis i ...1977308746
changes in the activity of the ependyma in the infundibular recess of the brain of rana esculenta l. in the annual cycle.volume of the cell nuclei of the ependyma of the infundibular recess was measured in 30 female and 30 male water frogs (rana esculenta l.) obtained from their natural environment, taking into account the phase of the annual cycle. karyometry of the ependymal cell nuclei in the infundibular recess in males and females showed statistically significant differences of volume (activity) in the annual cycle. the largest volume of nuclei of the ependymal cells in females and males was observed in the f ...1977308755
topography of cutaneous spinal ganglion cells in the frog (rana esculenta). 2004308834
seasonal variations in fat body metabolism of the green frog rana esculenta (l.).rana esculenta (l.), kept under natural conditions, show almost constant body weights in the annual cycle. fat body weight, however, has a distinct maximum in october decreasing continuously to a may minimum which is also evident in the fat body index. the triglyceride and protein contents show the same course. suprisingly high amounts of glycogen are found, which reach a maximum in august.2003308886
annual variations in the total lipid and protein content of the liver, fat body, ovary and plasma of the female frog (rana esculenta l.).the concentrations of lipid and protein in the ovary, fat body, liver and plasma of the female frog (rana esculenta l.) were found to exhibit marked seasonal variations. there was an interesting correspondence between the depletion of lipid in the plasma and fat body and an increased level of lipid in the ovary. it would appear that oestrogenic steroids stimulate and increase the concentrations of lipids in the plasma, whereas pituitary gonadotrophins influence the uptake of lipids by ovarian ti ...2003308977
[the identity of rana esculenta bilmaensis from the southern sahara (author's transl)]. 1978309170
the amino-acid sequence of troponin c from frog skeletal muscle.the primary structure of the troponin c from skeletal muscle of the frog rana esculenta has been determined. the amino acid sequence was deduced from amino acid determinations of peptides obtained after cleavage with cyanogen bromide. overlapping peptides were isolated from tryptic digests of performic-acid-oxidized troponin c and phthalylated performic-acid-oxidized troponin c. all overlaps have been determined except for the arg-ile sequence at position 103--104, which has been obtained by com ...1978309817
triploid f2 progeny of water frogs (rana esculenta complex). 1978309835
some hydroxysteroid dehydrogenases in the growing ovarian follicles of green frog rana esculenta l. 1993309860
non-ependymal cilia in the habenulae and the interpeduncular nucleus of the frog tadpole.cilia of the 9 + 2 pattern are found electron microscopically in nonependymal cells of the habenulae and the interpeduncular nucleus of the tadpole of rana esculenta at an early stage of development (8 mm length, head to tip of tail). a comparison is made between these and the ependymal and sensory cilia in the same specimens. the cilia project into the neuropil emerging from a perikaryon rich in free ribosomes and displaying a prominent golgi apparatus. these perikarya contain dense core vesicl ...1978310346
immunochemical investigations on water frog eggs: comparative studies on rana ridibunda, rana lessonae and their hybrid rana esculenta.eggs of rana ridibunda, rana lessonae and their hybrid rana esculenta were examined for their immunochemical properties. the reaction spectra obtained confirm the hybrid origin of rana esculenta.1978310442
sensitivity change of the chromatic response of the pineal organ of the frog, rana esculenta, by light adaptation [proceedings]. 1978310455
the current voltage relationship of the delayed outward current in the heart of the frog (rana esculenta) and the tortoise (testudo germani).steady state and non steady state i-v relationships of the resting membrane and delayed rectifying membrane were analysed by applying trapezoid voltage clamp pulses on atrial fibres isolated from the frog and the tortoise. the fibres were disposed in a perfusion chamber for double sucrose gap. in both types of preparation, a component of delayed rectification current was identified which was activated following a comparable time course. the amplitude of the delayed rectification current, when ex ...1978310540
ploidy of progeny from different egg size classes of rana esculenta l. 1978310778
non linear volume flow dependence on osmotic pressure difference in frog skin.the volume flow dependence upon the osmotic pressure difference of both impermeant (sucrose) and permeable (nacl) species has been investigated in leg skin bags of rana esculenta. it is concluded: 1. the hydration-dehydration error in the flow measurement with leg skin bags is negligible. 2. the flow-force relationship is non-linear. 3. unstirred layers and solute permeation have little, if any, influence on non linearity. 4. structural modifications of the skin induced with hypertonic solutions ...1978310878
[preliminary observations on the incorporation of tyrosine-c14 in melanin isolated from the skin and liver of rana esculenta l]. 2001311220
preliminary studies on the uptake of labeled mammalian gonadotropins by ovary and oviduct of the green frog, rana esculenta, in vivo.in hypophysectomized females, rana esculenta, a significant uptake of labeled ovine fsh and lh was evident in both the ovary and oviduct. this binding was specific only for the ovary. ovariectomy did not modify the affinity of the oviduct for these gonadotropins. the possibility of the presence of discrete receptor molecules for fsh and lh in the ovary of rana esculenta is discussed.2001311221
circannual and circadian rhythms in the concentration of corticosterone in the plasma of the edible frog (rana esculenta l.).for a period of 21 months between may 1974 and september 1976, circadian variations in the plasma concentration of corticosterone were studied by competitive protein-binding techniques in mature male and female edible frogs living in their natural environment. blood samples were taken from 8 to 12 frogs six times daily and conventional and cosinor methods were used for statistical analysis. circadian rhythms were not detected during february and march (time of hibernation). circannual rhythms we ...1979311807
moulting in rana esculenta: development of mitochondria-rich cells, morphological changes of the epithelium and sodium transport.the present study concerns moulting of the skin in rana esculenta in vivo and in vitro. the evolution of mitochondria-rich cells (mrc) and changes in the epithelium during moulting were followed. the greater part of the mrc are lost during moulting, either because they remain attached to the old stratum corneum or because they are left in contact with the external medium and degenerate. the cells thus lost leave deep impressions in the new stratum corneum which disappear progressively. before an ...1989313252
effects of fusion in pairs on the development of anurans rana dalmatina and rana esculenta.of 252 heterospecific, parabiotic pairs of rana dalmatina and r. esculenta, fused during embryonic life, 87 died because the larva of r. dalmatina died at the beginning of its circulation. later 89 pairs died when the r. esculenta larva died suddenly at the beginning of its independent feeding. seventy-one pairs survived at the end of the metamorphic climax. death in the first case is considered to result from some toxic effect, in the second from an immunological reaction. in the surviving pair ...1989313357
inhibition of the ach-induced extracurrent on atrial fibres of rana esculenta by atropine and tetraethylammonium chloride [proceedings]. 1989313442
restoration of behaviorial responses in the frog rana esculenta during regeneration of optic nerve fibers. 2017314069
[biological effects of low frequency vibration on the embryonal development of bufo vulgaris and rana esculenta]. 2006314103
characterization of a cytoplasmic androgen receptor in the male secondary sexual character of green frog (rana esculenta). 1966316045
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