Publications

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[monthly report on eradication of aedes aegypti in american countries, december, 1953]. 195413181976
healing of gut wounds in the mosquito aedes aegypti (l.) and the leafhopper orosius argentatus (ev.). 195313126036
transmission of a west nile-like virus by aedes aegypti. 195313090296
[monthly report on eradication of aedes aegypti in american countries, january, 1953]. 195313066562
the cutaneous reaction to the bite of the mosquito aëdes aegypti (l.) and its alleviation by the topical application of an antihistaminic cream (pyribenzamine). 195313044474
[monthly report on the progress of campaign for eradication of aedes aegypti in american countries, october, 1952]. 195313051435
aedes aegypti surveys in three cities in alabama in 1952. 195313023298
[monthly report on the campaign of eradication of aedes aegypti in american countries, september, 1952]. 195313041772
the growth stimulating effect of apf, terramycin hydrochloride, vitamin b12 and an undetermined factor x upon aedes aegypti (l) diptera, culicidae. 195313007931
[aedes aegypti eradication campaign in chile]. 201612977855
[eradication of aedes aegypti and control of yellow fever; four year continental program]. 195114886443
[results of ddt application in french guiana; destruction of the aedes aegypti and spectabular reduction of malaria]. 195124541063
[innocuousness of the addition of 1 ppm of ddt to drinking water for the eradication of aedes aegypti]. 195114821037
estimation of traces of ddt using aedes aegypti larvae as a biological indicator. 195114817816
some nutritional requirements of adult mosquitoes (aedes aegypti) for oviposition. 195114851026
[attempt at control of aedes aegypti by application of ddt in water tanks]. 195014783641
[control of aedes aegypti in chile]. 195015411454
aedes aegypti and other mosquito control measures in port sudan. 194915408260
rearing of anopheles quadrimaculatus say and aedes aegypti (l.) in the laboratory. 194915406584
bioassay systems for the pyrethrins; water-base sprays against aëdes aegypti l. and other flying insects. 194918151949
toxicity of limewash containing ddt or gammexane to mosquitos, aëdes aegypti, l. 194818865550
extermination of aëdes aegypti in khartoum. 194818900760
the nutrition of the larva of aëdes aegypti linnaeus; protein and amino-acid requirements. 194818122654
the nutrition of the larva of aëdes aegypti linnaeus; lipid requirements. 194818105885
the nutrition of the larva of aëdes aegypti linnaeus. 4. protein and amino-acid requirements. 194816748417
the nutrition of the larva of aëdes aegypti linnaeus. 3. lipid requirements. 194816748416
observations on the effect of microclimate on biting by aëdes aegypti (l.) (dipt., culicid.). 194718920748
aedes aegypti control in the absence of a piped potable water supply. 194718897110
further observations on the nutritional requirements of the larva of aedes aegypti l. 194720269871
ddt and aedes aegypti control in british guiana. 194720264247
the inhibition of growth of larvae of aedes aegypti by certain anti-malarial drugs. 194720265407
winter survival of aedes aegypti in houston, texas. 194620995756
chlorine as a possible ovicide for aedes aegypti eggs. 194621027331
experiments upon the feeding of aedes aegypti through animal membranes with a view to applying this method to the chemotherapy of malaria. 194621014255
occurrence of aedes aegypti in british guiana. 194520998212
aedes aegypti linnaeus, the yellow fever mosquito, in central missouri. 194217752151
measures instituted for the control of aëdes aegypti. 194018015233
the absence from the urine of pernicious anemia patients of a mosquito growth factor present in normal urine.extracts prepared from the urine of normal persons or patients with aplastic anemia or leukemia contain a substance, possibly flavine or a flavine compound, which under suitable conditions of test enhances the growth of larvae of the mosquito, aëdes aegypti. this substance is lacking, or is present in much smaller amount, in extracts from the urine of pernicious anemia patients showing symptoms of the disease. extracts from the urine of the same patients after adequate treatment contain as much ...193819870733
the yellow-fever mosquito. 190617737726
concerning the geographic distribution of the yellow fever mosquito. 190319601151
a study on container breeding mosquitoes with special reference to aedes (stegomyia) aegypti and aedes albopictus in thiruvananthapuram district, india.the district of thiruvananthapuram reports the maximum number of cases of dengue in the state of kerala. to determine the larval diversity, density and breeding site preferences of aedes mosquitoes, during pre-monsoon and monsoon periods in urban and rural areas of thiruvananthapuram district.201424717199
identification of wild collected mosquito vectors of diseases using gas chromatography-mass spectrometry in jazan province, saudi arabia.thirty-three species of mosquitoes have been reported from the kingdom of saudi arabia. several of these mosquitoes, anopheles gambiae giles s.l., anopheles stephensi liston, culex pipiens linnaeus, culex quinquefasciatus say, culex tritaeniorhynchus giles, stegomyia aegypti (linnaeus) and aedimorphus vexans arabiensis (patton) are known vectors of human and animal diseases. in this study, the cuticular hydrocarbon profiles of eight mosquito species using gas chromatography-mass spectrometry wer ...201324259205
larvicidal activity of few select indigenous plants of north east india against disease vector mosquitoes (diptera: culicidae).mosquitoes are the vectors of several life threatening diseases like dengue, malaria, japanese encephalitis and lymphatic filariasis, which are widely present in the north-eastern states of india. investigations on five local plants of north-east india, selected on the basis of their use by indigenous communities as fish poison, were carried out to study their mosquito larvicidal potential against anopheles stephensi (malaria vector), stegomyia aegypti (dengue vector) and culex quinquefasciatus ...201525801251
mosquitoes of western uganda.the mosquito fauna in many areas of western uganda has never been studied and is currently unknown. one area, bwamba county, has been previously studied and documented but the species lists have not been updated for >40 yr. this paucity of data makes it difficult to determine which arthropod-borne viruses pose a risk to human or animal populations. using co2 baited-light traps, from 2008 through 2010, 67,731 mosquitoes were captured at five locations in western uganda including mweya, sempaya, m ...201223270157
abundance, diversity, and distribution of mosquito vectors in selected ecological regions of kenya: public health implications.the diversity of mosquito arbovirus vectors was investigated to define regional risk of arbovirus transmission in kenya. mosquitoes were sampled between april, 2007 and december, 2010 at thirteen sites across seven administrative provinces and ecological zones. cdc light traps were used to collect mosquitoes while human-landing collection was conducted in five of the sites to target day-feeding aedes (stegomyia) species. over 524,000 mosquitoes were collected and identified into 101 species, 30 ...201323701618
zika virus alters the microrna expression profile and elicits an rnai response in aedes aegypti mosquitoes.zika virus (zikv), a flavivirus transmitted primarily by aedes aegypti, has recently spread globally in an unprecedented fashion, yet we have a poor understanding of host-microbe interactions in this system. to gain insights into the interplay between zikv and the mosquito, we sequenced the small rna profiles in zikv-infected and non-infected ae. aegypti mosquitoes at 2, 7 and 14 days post-infection. zika induced an rnai response in the mosquito with virus-derived short interfering rnas and piwi ...201728715413
biopolymer zein-coated gold nanoparticles: synthesis, antibacterial potential, toxicity and histopathological effects against the zika virus vector aedes aegypti.the control of multidrug-resistant bacteria as well as insect pests and vectors is timely and important now a days. the present study was designed to evaluate the in vitro antibacterial, antibiofilm and mosquito larvicidal effects of gold nanoparticles synthesized using the zein biopolymer (ze-aunps) against gram positive (bacillus pumilus and bacillus subtilis), gram negative (shigella sonnei and pseudomonas aeruginosa) bacteria and third instar larvae of the dengue and zika virus vector aedes ...201728654862
cell fusing agent virus and dengue virus mutually interact in aedes aegypti cell lines.the genus flavivirus contains more than 70 single-stranded, positive-sense arthropod-borne rna viruses. some flaviviruses are particularly medically important to humans and other vertebrates including dengue virus (denv), west nile virus, and yellow fever virus. these viruses are transmitted to vertebrates by mosquitoes and other arthropod species. mosquitoes are also infected by insect-specific flaviviruses (isfs) that do not appear to be infective to vertebrates. cell fusing agent virus (cfav) ...201728761113
experimental infection with and maintenance of cell fusing agent virus (flavivirus) in aedes aegypti.during the past two decades, there has been a dramatic increase in the recognition and characterization of novel insect-specific flaviviruses (isfvs). some of these agents are closely related to important mosquito-borne flavivirus pathogens. results of experimental studies suggest that mosquitoes and mosquito cell cultures infected with some isfvs are refractory to superinfection with related flavivirus pathogens; and it has been proposed that isfvs potentially could be used to alter the vector ...201728719335
activation of aedes aegypti prophenoloxidase-3 and its role in the immune response against entomopathogenic fungi.serine protease cascade-mediated melanization is an important innate immune response in insects and crustaceans, which involves the proteolytic activation of prophenoloxidase (ppo). in this study, we investigated the role of aedes aegypti ppo3 in antifungal immune defence. we expressed and purified recombinant ppo3 (rppo3) in escherichia coli and demonstrated that rppo3 was activated by ethanol and, to a lesser extent, by cetylpyridinium chloride. in the presence of cu(2+) , rppo3 exhibited enzy ...201728556276
understanding the role of micrornas in the interaction of aedes aegypti mosquitoes with an insect-specific flavivirus.the flavivirus genus contains some of the most prevalent vector-borne viruses, such as the dengue, zika and yellow fever viruses that cause devastating diseases in humans. however, the insect-specific clade of flaviviruses is restricted to mosquito hosts, albeit they have retained the general features of the genus, such as genome structure and replication. the interactions between insect-specific flaviviruses (isfs) and their mosquito hosts are largely unknown. pathogenic flaviviruses are known ...201728699859
observations on longevity and egg production in aedes (stegomyia) aegypti linn. mosquitoes infected with uganda s virus. 196214013820
transposition of mutator-like transposable elements (mules) resembles hat and transib elements and v(d)j recombination.mutator-like transposable elements (mules) are widespread across fungal, plant and animal species. despite their abundance and importance as genetic tools in plants, the transposition mechanism of the mule superfamily was previously unknown. discovery of the muta1 element from aedes aegypti and its successful transposition in yeast facilitated the characterization of key steps in muta1 transposition. here we show that purified transposase binds specifically to the muta1 ends and catalyzes excisi ...201728482040
ascogregarina taiwanensis infection in aedes aegypti and aedes albopictus in santa catarina, south brazil.this study registers ascogregarina spp. infection in field populations of aedes aegypti and aedes albopictus in a subtropical region of brazil.201728562761
molecular characterization of the gene profile of bacillus thuringiensis berliner isolated from brazilian ecosystems and showing pathogenic activity against mosquito larvae of medical importance.the occurrence of aedes aegypti, culex quinquefasciatus, and mosquitoes of the genus anopheles potentiate the spread of several diseases, such as dengue, zika, chikungunya, urban yellow fever, filariasis, and malaria, a situation currently existing in brazil and in latin america. control of the disease vectors is the most effective tool for containing the transmission of the pathogens causing these diseases, and the bacterium bacillus thuringiensis var. israelensis has been widely used and has s ...201728823909
mosquitocidal potential of silver nanoparticles synthesized using local isolates of bacillus thuringiensis subsp. israelensis and their synergistic effect with a commercial strain of b. thuringiensis subsp. israelensis.control of larval stages of aedes aegypti is considered an effective approach for preventing outbreaks of dengue fever. in this work, silver nanoparticles (ag nps) were synthesized using the supernatant and insecticidal proteins from local isolates of bacillus thuringiensis subsp. israelensis (bti). mosquitocidal activity assays against a. aegypti larvae revealed that the highest toxicity was obtained from the ag nps synthesized using supernatant of bti k55 and the inclusion proteins of bti k46 ...201728754251
toward mosquito control with a green alga: expression of cry toxins of bacillus thuringiensis subsp. israelensis (bti) in the chloroplast of chlamydomonas.we are developing chlamydomonas strains that can be used for safe and sustainable control of mosquitoes, because they produce proteins from bacillus thuringiensis subsp. israelensis (bti) in the chloroplast. chlamydomonas has a number of advantages for this approach, including genetic controls that are not generally available with industrial algae. the bti toxin has been used for mosquito control for > 30 years and does not engender resistance; it contains three cry proteins, cry4aa (135 kda), c ...201728713202
molecular characterization of indigenous bacillus thuringiensis strains isolated from kashmir valley.bacillus thuringiensis (bt) being an eco-friendly bioinsecticide is effectively used in pest management strategies and, therefore, isolation and identification of new strains effective against a broad range of target pests is important. in the present study, new indigenous b. thuringiensis strains were isolated and investigated so that these could be used as an alternative and/or support the current commercial strains/cry proteins in use. for this, 159 samples including soil, leaf and spider web ...201728597156
functional characterization of aedes aegypti alkaline phosphatase alp1 involved in the toxicity of cry toxins from bacillus thuringiensis subsp. israelensis and jegathesan.presently three major groups of proteins from aedes aegypti, cadherin, alkaline phosphatases (alp) and aminopeptidases n (apn), have been identified as cry11aa toxin receptors. to further characterize their role on toxicity, transgenic mosquitoes with silenced aedes cadherin expression were previously generated and the role of cadherin in mediating the toxicity of four different mosquitocidal toxins (cry11aa, cry11ba, cry4aa and cry4ba) was demonstrated. here, we investigated the role of another ...201728587836
evaluating the vector control potential of the in2care® mosquito trap against aedes aegypti and aedes albopictus under semifield conditions in manatee county, florida.successful integrated vector management programs may need new strategies in addition to conventional larviciding and adulticiding strategies to target aedes aegypti and ae. albopictus, which can develop in small, often cryptic, artificial and natural containers. the in2care® mosquito trap was recently developed to target and kill larval and adult stages of these invasive container-inhabiting aedes mosquitoes by utilizing autodissemination. gravid females that visit the trap pick up pyriproxyfen ...201728854105
mosquitoes can harbour yeasts of clinical significance and contribute to their environmental dissemination.there is still a lack of studies on fungal microbiota in mosquitoes, compared with the number available on bacterial microbiota. this study reports the identification of yeasts of clinical significance in laboratory mosquito species: anopheles gambiae, anopheles stephensi, culex quinquefasciatus, aedes albopictus and aedes aegypti. among the yeasts isolated, they focused on the opportunistic pathogen candida parapsilosis, since there is a need to better understand breakthrough candidaemia with r ...201728714286
vector competence of populations of aedes aegypti from three distinct cities in kenya for chikungunya virus.in april, 2004, chikungunya virus (chikv) re-emerged in kenya and eventually spread to the islands in the indian ocean basin, south-east asia, and the americas. the virus, which is often associated with high levels of viremia in humans, is mostly transmitted by the urban vector, aedes aegypti. the expansion of chikv presents a public health challenge both locally and internationally. in this study, we investigated the ability of ae. aegypti mosquitoes from three distinct cities in kenya; mombasa ...201728820881
co-infection of mosquitoes with chikungunya and dengue viruses reveals modulation of the replication of both viruses in midguts and salivary glands of aedes aegypti mosquitoes.arthropod-borne virus (arbovirus) infections cause several emerging and resurgent infectious diseases in humans and animals. chikungunya-affected areas often overlap with dengue-endemic areas. concurrent dengue virus (denv) and chikungunya virus (chikv) infections have been detected in travelers returning from regions of endemicity. chikv and denv co-infected aedes albopictus have also been collected in the vicinity of co-infected human cases, emphasizing the need to study co-infections in mosqu ...201728777313
high-resolution structure of a kazal-type serine protease inhibitor from the dengue vector aedes aegypti.blood-feeding exoparasites are rich sources of protease inhibitors, and the mosquito aedes aegypti, which is a vector of dengue virus, yellow fever virus, chikungunya virus and zika virus, is no exception. aati is a single-domain, noncanonical kazal-type serine proteinase inhibitor from a. aegypti that recognizes both digestive trypsin-like serine proteinases and the central protease in blood clotting, thrombin, albeit with an affinity that is three orders of magnitude lower. here, the 1.4 å res ...201728777090
evidence of dengue and chikungunya virus co-infection and circulation of multiple dengue serotypes in a recent indian outbreak.in india, dengue endemic areas overlap with chikungunya-affected areas and both the viruses are transmitted by same vector, aedes aegypti - thereby increasing opportunity of co-infection by both viruses. present study was carried out to understand the denv-chikv infection dynamics during recent outbreaks in eastern india (west bengal state) and its implication on disease manifestations. blood was collected from 326 symptomatic febrile patients. patients' serum was subjected to serological diagno ...201728756561
transmission risk of two chikungunya lineages by invasive mosquito vectors from florida and the dominican republic.between 2014 and 2016 more than 3,800 imported human cases of chikungunya fever in florida highlight the high risk for local transmission. to examine the potential for sustained local transmission of chikungunya virus (chikv) in florida we tested whether local populations of aedes aegypti and aedes albopictus show differences in susceptibility to infection and transmission to two emergent lineages of chikv, indian ocean (ioc) and asian genotypes (ac) in laboratory experiments. all examined popul ...201728749964
assessment of the probability of autochthonous transmission of chikungunya virus in canada under recent and projected climate change.chikungunya virus (chikv) is a reemerging pathogen transmitted by aedes aegypti and aedes albopictus mosquitoes. the ongoing caribbean outbreak is of concern due to the potential for infected travelers to spread the virus to countries where vectors are present and the population is susceptible. although there has been no autochthonous transmission of chikv in canada, there is concern that both ae. albopictus and chikv will become established, particularly under projected climate change. we devel ...201728731409
the medicinal chemistry of chikungunya virus.arthropod-borne viruses (arboviruses) are an important threat to human and animal health globally. among these, zoonotic diseases account for billions of cases of human illness and millions of deaths every year, representing an increasing public health problem. chikungunya virus belongs to the genus alphavirus of the family togariridae, and is transmitted mainly by the bite of female mosquitoes of the aedes aegypti and/or a. albopictus species. the focus of this review will be on the medicinal c ...201728689975
high risk for chikungunya virus to initiate an enzootic sylvatic cycle in the tropical americas.chikungunya virus (chikv) has dispersed in the americas since 2013, and its range of distribution has overlapped large forested areas. herein, we assess vector competence of two sylvatic neotropical mosquito species, haemagogus leucocelaenus and aedes terrens, to evaluate the risk of chikv to initiate a sylvatic cycle in the continent.201728662031
first report of naturally infected aedes aegypti with chikungunya virus genotype ecsa in the americas.the worldwide expansion of new emergent arboviruses such as chikungunya and zika reinforces the importance in understanding the role of mosquito species in spreading these pathogens in affected regions. this knowledge is essential for developing effective programs based on species specificity to avoid the establishment of endemic transmission cycles sustained by the identified local vectors. although the first autochthonous transmission of chikungunya virus was described in 2014 in the north of ...201728614394
immunoglobulin-responsive chikungunya encephalitis: two case reports.chikungunya virus is an alphavirus transmitted by the mosquito aedes, mainly aedes aegypti and aedes albopictus, that can cause acute illness, mostly self-limited, characterized by fever, maculopapular rash, and disabling polyarthritis/arthralgia, with an incubation period of 1 to 12 days. chikungunya was largely regarded as a non-fatal and self-limited disease, but recently, serious cases have been reported including some with severe involvement of the nervous system, such as meningoencephaliti ...201728577289
mosquito co-infection with zika and chikungunya virus allows simultaneous transmission without affecting vector competence of aedes aegypti.zika virus (zikv) and chikungunya virus (chikv) are highly pathogenic arthropod-borne viruses that are currently a serious health burden in the americas, and elsewhere in the world. zikv and chikv co-circulate in the same geographical regions and are mainly transmitted by aedes aegypti mosquitoes. there is a growing number of case reports of zikv and chikv co-infections in humans, but it is uncertain whether co-infection occurs via single or multiple mosquito bites. here we investigate the poten ...201728570693
wmel limits zika and chikungunya virus infection in a singapore wolbachia-introgressed ae. aegypti strain, wmel-sg.zika (zikv) and chikungunya (chikv) viruses are emerging aedes-borne viruses that are spreading outside their known geographic range and causing wide-scale epidemics. it has been reported that these viruses can be transmitted efficiently by ae. aegypti. recent studies have shown that ae. aegypti when transinfected with certain wolbachia strains shows a reduced replication and dissemination of dengue (denv), chikungunya (chikv), and yellow fever (yfv) viruses. the aim of this study was to determi ...201728542240
[arboviruses also have an american dream].some arboviruses that originated in the old world have been introduced by humans into the american continent. the first of them was the yellow fever virus, coming from the west african coast with slaves in the 17th-19th centuries, followed by dengue viruses, which were always prevalent within the americas. next was thewest nile virus, introduced in new york in 1999, that spread in only a few years over the whole continent. then, chikungunya virus arrived on saint martin island in 2013 after its ...201728509947
the midgut transcriptome of aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape.the mosquito aedes aegypti is the primary vector for medically important arthropod-borne viruses, including chikungunya virus (chikv). following oral acquisition, an arbovirus has to persistently infect several organs in the mosquito before becoming transmissible to another vertebrate host. a major obstacle an arbovirus has to overcome during its infection cycle inside the mosquito is the midgut escape barrier, representing the exit mechanism arboviruses utilize when disseminating from the midgu ...201728506207
clinical features and neurologic complications of children hospitalized with chikungunya virus in honduras.the first case of chikungunya virus in honduras was identified in 2014. the virus has spread widely across honduras via the aedes aegypti mosquito, leading to an outbreak of chikungunya virus (chikv) in 2015 that significantly impacted children. a retrospective chart review of 235 children diagnosed with chikv and admitted to the national autonomous university of honduras hospital escuela (hospital escuela) in tegucigalpa, honduras, was accomplished with patients who were assessed for clinical f ...201728459170
co-circulation of dengue virus serotypes with chikungunya virus in madhya pradesh, central india.dengue and chikungunya present with very similar signs and symptoms in the initial stage of illness and so it is difficult to distinguish them clinically. both are transmitted by aedes aegypti and aedes albopictus mosquitoes. this study was conducted with the aim to explore the co-circulation of dengue and chikungunya viruses in central india.201728607252
ensuring successful introduction of wolbachia in natural populations of aedes aegypti by means of feedback control.the control of the spread of dengue fever by introduction of the intracellular parasitic bacterium wolbachia in populations of the vector aedes aegypti, is presently one of the most promising tools for eliminating dengue, in the absence of an efficient vaccine. the success of this operation requires locally careful planning to determine the adequate number of individuals carrying the wolbachia parasite that need to be introduced into the natural population. the introduced mosquitoes are expected ...201728856446
influence of the mixtures composed of slow-release insecticide formulations against aedes aegypti mosquito larvae reared in pond water.vector borne diseases remain the major source of illness and death worldwide. aedes aegypti is the primary carrier of dengue and dengue haemorrhagic fever in many developing countries in the tropical world. because a. aegypti populations are becoming more and more resistant to conventional and non conventional insecticides, alternative strategies have to be rapidly implemented in the future for dengue vector control. the present study aimed to evaluate the larvicidal efficacy of slow-release for ...201728855810
human movement, cooperation and the effectiveness of coordinated vector control strategies.vector-borne disease transmission is often typified by highly focal transmission and influenced by movement of hosts and vectors across different scales. the ecological and environmental conditions (including those created by humans through vector control programmes) that result in metapopulation dynamics remain poorly understood. the development of control strategies that would most effectively limit outbreaks given such dynamics is particularly urgent given the recent epidemics of dengue, chik ...201728855386
a statewide survey for container-breeding mosquitoes in mississippi.container-breeding mosquitoes are important in public health due to outbreaks of zika, chikungunya, and dengue viruses. this paper documents the distribution of container-breeding mosquito species in mississippi, with special emphasis on the genus aedes. five sites in each of the 82 mississippi counties were sampled monthly between may 1 and august 31, 2016, and 50,109 mosquitoes in 14 species were collected. the most prevalent and widely distributed species found was ae. albopictus, being found ...201728854113
adulticidal susceptibility evaluation of aedes albopictus using new diagnostic doses in penang island, malaysia.insecticide-based vector control approaches are facing challenges due to the development of resistance in vector mosquitoes. therefore, a proper resistance surveillance program using baseline lethal concentrations is crucial for resistance management strategies. currently, the world health organization's (who) diagnostic doses established for aedes aegypti and anopheles species are being used to study the resistance status of aedes albopictus. in this study, we established the diagnostic doses f ...201728854111
toxicological effects of chemical constituents from piper against the environmental burden aedes aegypti liston and their impact on non-target toxicity evaluation against biomonitoring aquatic insects.dengue is the most rapidly spreading mosquito-borne viral disease in the world. the mosquito, aedes aegypti, also spreads yellow fever, chikungunya, and zika virus. as the primary vector for dengue, ae. aegypti now occurs in over 20 countries and is a serious concern with reports of increasing insecticide resistance. developing new treatments to manage mosquitoes are needed. formulation of crude volatile oil from piper betle leaves (pb-cvo) was evaluated as a potential treatment which showed lar ...201728852982
the elimination of the dengue vector, aedes aegypti, from brisbane, australia: the role of surveillance, larval habitat removal and policy.aedes aegypti (l.) (diptera: culicidae) is a highly invasive mosquito whose global distribution has fluctuated dramatically over the last 100 years. in australia the distribution of ae. aegypti once spanned the eastern seaboard, for 3,000 km north to south. however, during the 1900s this distribution markedly reduced and the mosquito disappeared from its southern range. numerous hypotheses have been proffered for this retraction, however quantitative evidence of the mechanisms driving the disapp ...201728846682
zika, chikungunya, and other emerging vector-borne viral diseases.arthropod-borne viruses (arboviruses) have a long history of emerging to infect humans, but during recent decades, they have been spreading more widely and affecting larger populations. this is due to several factors, including increased air travel and uncontrolled mosquito vector populations. emergence can involve simple spillover from enzootic (wildlife) cycles, as in the case of west nile virus accompanying geographic expansion into the americas; secondary amplification in domesticated animal ...201728846489
sero-surveillance of dengue in the city lahore, pakistan.to conduct sero-surveillance of dengue cases, and to find out the demographic and socio-economic status of dengue patients.201728839300
carryover effects of larval exposure to different environmental bacteria drive adult trait variation in a mosquito vector.conditions experienced during larval development of holometabolous insects can affect adult traits, but whether differences in the bacterial communities of larval development sites contribute to variation in the ability of insect vectors to transmit human pathogens is unknown. we addressed this question in the mosquito aedes aegypti, a major arbovirus vector breeding in both sylvatic and domestic habitats in sub-saharan africa. targeted metagenomics revealed differing bacterial communities in th ...201728835919
the quantitative structure-insecticidal activity relationships from plant derived compounds against chikungunya and zika aedes aegypti (diptera:culicidae) vector.the insecticidal activity of a series of 62 plant derived molecules against the chikungunya, dengue and zika vector, the aedes aegypti (diptera:culicidae) mosquito, is subjected to a quantitative structure-activity relationships (qsar) analysis. the replacement method (rm) variable subset selection technique based on multivariable linear regression (mlr) proves to be successful for exploring 4885 molecular descriptors calculated with dragon 6. the predictive capability of the obtained models is ...201728830053
maintaining aedes aegypti mosquitoes infected with wolbachia.aedes aegypti mosquitoes experimentally infected with wolbachia are being utilized in programs to control the spread of arboviruses such as dengue, chikungunya and zika. wolbachia-infected mosquitoes can be released into the field to either reduce population sizes through incompatible matings or to transform populations with mosquitoes that are refractory to virus transmission. for these strategies to succeed, the mosquitoes released into the field from the laboratory must be competitive with na ...201728829414
limited transmission potential of takeda's tetravalent dengue vaccine candidate by aedes albopictus.recombinant live-attenuated chimeric tetravalent dengue vaccine viruses, tdv-1, -2, -3, and -4, contain the premembrane and envelope genes of dengue virus serotypes 1-4 in the replicative background of the attenuated dengue virus type-2 (denv-2) pdk-53 vaccine strain. previous results have shown that these recombinant vaccine viruses demonstrate limited infection and dissemination in aedes aegypti and are unlikely to be transmitted by the primary mosquito vector of denvs. in this report, we expa ...201728820715
scaling up of an innovative intervention to reduce risk of dengue, chikungunya, and zika transmission in uruguay in the framework of an intersectoral approach with and without community participation.to contribute to the prevention of dengue, chikungunya, and zika, a process of scaling up an innovative intervention to reduce aedes aegypti habitats, was carried out in the city of salto (uruguay) based on a transdisciplinary analysis of the eco-bio-social determinants. the intervention in one-third of the city included the distributions of plastic bags for all households to collect all discarded water containers that were recollected by the ministry of health and the municipality vector contro ...201728820690
assessment of risk of dengue and yellow fever virus transmission in three major kenyan cities based on stegomyia indices.dengue (den) and yellow fever (yf) are re-emerging in east africa, with contributing drivers to this trend being unplanned urbanization and increasingly adaptable anthropophilic aedes (stegomyia) vectors. entomological risk assessment of these diseases remains scarce for much of east africa and kenya even in the dengue fever-prone urban coastal areas. focusing on major cities of kenya, we compared den and yf risk in kilifi county (den-outbreak-prone), and kisumu and nairobi counties (no document ...201728817563
an economic evaluation of vector control in the age of a dengue vaccine.dengue is a rapidly emerging vector-borne neglected tropical disease, with a 30-fold increase in the number of cases reported since 1960. the economic cost of the illness is measured in the billions of dollars annually. environmental change and unplanned urbanization are conspiring to raise the health and economic cost even further beyond the reach of health systems and households. the health-sector response has depended in large part on control of the aedes aegypti and ae. albopictus (mosquito) ...201728806786
wolbachia-mediated virus blocking in the mosquito vector aedes aegypti.viruses transmitted by mosquitoes such as dengue, zika and west nile cause a threat to global health due to increased geographical range and frequency of outbreaks. the bacterium wolbachia pipientis may be the solution reducing disease transmission. though commonly missing in vector species, the bacterium was artificially and stably introduced into aedes aegypti to assess its potential for biocontrol. when infected with wolbachia, mosquitoes become refractory to infection by a range of pathogens ...201728805637
multiple introductions of the dengue vector, aedes aegypti, into california.the yellow fever mosquito aedes aegypti inhabits much of the tropical and subtropical world and is a primary vector of dengue, zika, and chikungunya viruses. breeding populations of a. aegypti were first reported in california (ca) in 2013. initial genetic analyses using 12 microsatellites on collections from northern ca in 2013 indicated the south central us region as the likely source of the introduction. we expanded genetic analyses of ca a. aegypti by: (a) examining additional northern ca sa ...201728796789
dengue-1 virus and vector competence of aedes aegypti (diptera: culicidae) populations from new caledonia.dengue virus (denv) is the arbovirus with the highest incidence in new caledonia and in the south pacific region. in 2012-2014, a major denv-1 outbreak occurred in new caledonia. the only known vector of denv in new caledonia is aedes aegypti but no study has yet evaluated the competence of new caledonia ae. aegypti populations to transmit denv. this study compared the ability of field-collected ae. aegypti from different locations in new caledonia to transmit the denv-1 responsible for the 2012 ...201728793920
intelligent monitoring of aedes aegypti in a rural area of rio de janeiro state, brazil.the aim of this research was to monitor the presence of females of aedes aegypti (linnaeus, 1762) on the seropédica municipality, rio de janeiro state, from 2010 to 2013. for this purpose, the intelligent dengue monitoring (im-dengue) and intelligent virus monitoring (im-virus) developed by universidade federal de minas gerais (ecovec - minas gerais, brazil), were used. im-dengue is a tool that allows achieving a weekly overview of a. aegypti infestation, while im-virus is another tool that allo ...201728793020
microrna-275 targets sarco/endoplasmic reticulum ca2+ adenosine triphosphatase (serca) to control key functions in the mosquito gut.the yellow fever mosquito aedes aegypti is the major vector of arboviruses, causing numerous devastating human diseases, such as dengue and yellow fevers, chikungunya and zika. female mosquitoes need vertebrate blood for egg development, and repeated cycles of blood feeding are tightly linked to pathogen transmission. the mosquito's posterior midgut (gut) is involved in blood digestion and also serves as an entry point for pathogens. thus, the mosquito gut is an important tissue to investigate. ...201728787446
eco-friendly fabrication of ag nanostructures using the seed extract of pedalium murex, an ancient indian medicinal plant: histopathological effects on the zika virus vector aedes aegypti and inhibition of biofilm-forming pathogenic bacteria.the control of zika virus mosquito vectors and well as the development of drugs in the fight against biofilm-forming microbial pathogens, are timely and important challenges in current bionanoscience. here we focused on the eco-friendly fabrication of ag nanostructures using the seed extract of pedalium murex, an ancient indian medicinal plant. initial confirmation of ag nanoparticles (agnps) production was showed by a color change from transparent to dark brown. the uv-visible spectrum (476nm), ...201728772238
spatial distribution of aedes aegypti and aedes albopictus in relation to geo-ecological features in south andaman, andaman and nicobar islands, india.the study was undertaken in south andaman district, comprising three tehsils, viz. port blair, ferrargunj and little andaman tehsils, respectively. intensive pupal infestation surveys were carried out along the national highway (nh 223), the main passenger and trade route, referred to as great andaman trunk road. sampling locations at every 3 km were geo-referenced with global positioning system unit. a total of 17314 water collections were examined from 29 locations across the south andaman dis ...201728770695
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