| parasitic zoonoses in papua new guinea. | relatively few species of zoonotic parasites have been recorded in humans in papua new guinea. a greater number of potentially zoonotic species, mostly nematodes, occur in animals but are yet to be reported from humans. protozoa is the best represented group of those infecting man, with giardia duodenalis, cryptosporidium parvum, cyclospora cayetanesis, toxoplasma gondii, sarcocystis spp., entamoeba polecki, balantidium coli and, possibly, blastocystis hominis. the only zoonotic helminths infect ... | 2005 | 15831107 |
| [value of the antigen with molecular mass of 32 000 in immunodiagnosis of angiostrongylus cantonensis]. | to evaluate the specificity and sensitivity of immunodiagnosis with the antigen with molecular mass of 32 000 of angiostrongyliasis cantonensis(ac32). | 2005 | 15837632 |
| spot light survey on fresh-water snails of medical importance in al fayoum governorate, egypt. | in a survey carried out during summer and autumn of 2004, for snails of medical importance, nine species were recovered. these were biomphalaria alexandrina, b. glabrata, b. pfeifferi, bulinus truncatus, b. forskalii, lymnaea natalensis, bellamya (=vivipara) unicolor, physa acuta and hydrobia musaensis. parasitological examination revealed that b. alexandrina, b. glabrata and l. natalensis harboured immature stages of their concerned trematode parasites. moreover, p. acuta harboured the immature ... | 2005 | 15880994 |
| a letter regarding a case of eosinophilic meningitis. | | 2005 | 15892262 |
| common antigenicities between angiostrongylus cantonensis and various species of snails. | studies on common antigenicities were carried out by using rabbit sera immunized with angiostrongylus cantonensis adult worms or the third stage larvae and antigens of various species of snails and vice versa by the immunoblotting technique. the results obtained are summarized as follows: (1) common antigenicities between a. cantonensis adult worms and snails susceptible to a. cantonensis were observed in a range of molecular weights of 14.3 to 200 kda. in puerto rican pigmented biomphalaria gla ... | 2004 | 15916068 |
| protease secreted by the infective larvae of angiostrongylus cantonensis and its role in the penetration of mouse intestine. | the infective third-stage larvae of angiostrongylus cantonensis secrete a proteolytic enzyme that is thought to be essential for both larval penetration into the intestinal wall of the host and full development. protease activity in these larvae during culture in vitro was determined by zymography, ph optimum, and substrate and inhibitor specificity. excretory-secretory (es) products of the third-stage larvae showed protease activity as three bands with molecular masses of 66, 30, and 23 kd by g ... | 2005 | 15964972 |
| [antigen analysis of angiostrongylus cantonensis in different developmental stages]. | to analyze the difference among antigens of angiostrongylus cantonensis in different developmental stages and identify dominant diagnostic antigen for angiostrongyliasis. | 2005 | 16042205 |
| longitudinal clinical and serological survey of abdominal angiostrongyliasis in guaporé, southern brazil, from 1995 to 1999. | abdominal angiostrongyliasis is a zoonotic infection caused by angiostrongylus costaricensis, a nematode with an intra-vascular location in the mesentery. our objective was to address several aspects of the natural history of this parasitosis, in a longitudinal clinical and seroepidemiological study. a total of 179 individuals living in a rural area with active transmission in southern brazil were followed for five years (1995-1999) resulting in yearly prevalence of 28.2%, 4.2%, 10%, 20.2% and 2 ... | 2005 | 16082477 |
| a case of eosinophilic meningitis following monitor lizard meat consumption, exacerbated by anthelminthics. | | 2005 | 16114775 |
| matrix metalloproteinases activity demonstrated in the infective stage of the nematodes, angiostrongylus cantonensis. | ingestion of the larval nematode angiostrongylus cantonensis can cause the human eosinophilic meningitis known as angiostrongyliasis. analysis of the extracts and excretory-secretory (es) products of a. cantonensis larvae and adult stages on gelatin substrate zymography demonstrated the presence of distinct gelatinolytic enzymes. in worm extracts, inhibitor studies showed that the metalloproteinases revealed in l(1) (23 kda), l(3) (66, 42 and 30 kda), young adult worm (72 and 94 kda) and adult w ... | 2005 | 16167160 |
| navigating parasite webs and parasite flow: emerging and re-emerging parasitic zoonoses of wildlife origin. | wildlife are now recognised as an important source of emerging human pathogens, including parasites. this paper discusses the linkages between wildlife, people, zoonotic parasites and the ecosystems in which they co-exist, revisits definitions for 'emerging' and 're-emerging', and lists zoonotic parasites that can be acquired from wildlife including, for some, estimates of the associated global human health burdens. the paper also introduces the concepts of 'parasite webs' and 'parasite flow', p ... | 2005 | 16168994 |
| igg1,igg2 and ige intrathecal synthesis in angiostrongylus cantonensis meningoencephalitis. | angiostrongylus cantonensis meningoencephalitis is an emergent zoonotic disease in the caribbean basin, characterized by the presence of eosinophils and third stage larva of the helmint. | 2005 | 16169562 |
| ocular angiostrongyliasis in a child--first case report from india. | a rare case report of angiostrongylus cantonensis (rat lung worm) from the eye is presented here. this worm generally causes eosinophilic meningo-encephalitis and accidentally infects humans by ingestion of uncooked snails, slugs, frogs etc. the child was presented to us with diminished vision in left eye. slit lamp examination showed an actively motile worm in the anterior chamber. surgical extraction of the worm was performed and it was identified as a. cantonensis. this is the first case of o ... | 2006 | 16186138 |
| chronic meningitis in thailand. clinical characteristics, laboratory data and outcome in patients with specific reference to tuberculosis and cryptococcosis. | the charts of 114 consecutive patients with chronic meningitis admitted to a general hospital in bangkok, thailand, between 1993 and 1999 were retrospectively reviewed. the most common causative agents were cryptococcus neoformans (54%) and mycobacterium tuberculosis (37%). hiv and other underlying diseases had a major impact on the presentation of chronic cryptococcal meningitis patients. compared to hiv-negative cryptococcal meningitis patients (21%), hiv-positives (79%) had a significantly lo ... | 2006 | 16254452 |
| [preparation and preliminary application of monoclonal antibodies against adult worm of angiostrongylus cantonensis]. | to develop and identify monoclonal antibodies (mcabs) against adult worm of angiostrongylus cantonensis and observe its applicability. | 2005 | 16296607 |
| pathological changes in the brains of rabbits experimentally infected with angiostrongylus cantonensis after albendazole treatment: histopathological and magnetic resonance imaging studies. | to determine the effects of albendazole on rabbits infected with larvae of angiostrongylus cantonensis by histopathological and magnetic resonance imaging (mri) techniques. | 2006 | 16319180 |
| [detection of angiostrongylus cantonensis circulating antigen by monoclonal antibodies]. | to prepare monoclonal antibodies (mcabs) against soluble antigens of adult worms of angiostrongylus cantonensis (a. cantonensis) on the purpose to detect cag of a. cantonensis. | 2005 | 16324407 |
| blood-brain barrier dysfunction occurring in mice infected with angiostrongylus cantonensis. | several indices were used to assess whether blood-brain barrier (bbb) damage occurs in neurological disorders. dysfunction of the bbb was surmised to be involved in the pathological changes of eosinophilic meningitis caused by the infection of angiostrongylus cantonensis. the mean concentration of protein and albumin in the cerebrospinal fluid (csf) of infected mice gradually increased from days 0 to 18 after infection and then rapidly increased 21 days after infection. the concentrations of pro ... | 2006 | 16332352 |
| angiostrongyliasis, mainland china. | | 2005 | 16355510 |
| angiostrongylus cantonensis: efficacy of albendazole-dexamethasone co-therapy against infection-induced plasminogen activators and eosinophilic meningitis. | angiostrongyliasis is one of the common causes leading to eosinophilic meningitis. tissue-type plasminogen activator (tpa) and urokinase-type plasminogen activator (upa) may play a role in the pathogenesis. administration of steroid drugs has been reported to possibly relieve the symptoms of eosinophilic meningitis. this study evaluates the curative effects of albendazole-dexamethasone co-therapy on eosinophilic meningitis in balb/c mice. assay indicators for the therapeutic effect include worm ... | 2006 | 16410005 |
| magnetic resonance imaging findings in the brains of rabbits infected with angiostrongylus cantonensis: a long-term investigation. | because magnetic resonance (mri) imaging is a superior technique in delineating pathological changes in cerebral angiostrongyliasis, it should also be an optimal imaging modality in monitoring long-term changes in the brains of animals infected with angiostrongylus cantonensis. in this study, mri and histological techniques were used to observe the changes in the brains of 7 rabbits infected with the third-stage larvae of a. canronensis. changes were monitored by mri from day 0 to day 207 postin ... | 2005 | 16419780 |
| human angiostrongylus cantonensis, jamaica. | | 2005 | 16485498 |
| necrotizing retinitis induced by angiostrongylus cantonensis. | to describe a case of bilateral necrotizing retinitis induced by angiostrongylus cantonensis. | 2006 | 16490516 |
| [screening and identification of therapeutic effect evaluation antigens of angiostrongyliasis]. | to identify antigens which may help evaluate the therapeutic effect of angiostrongyliasis from adult worm antigen of angiostrongylus cantonensis. | 2006 | 16546727 |
| abdominal angiostrongyliasis: a case with severe evolution. | a case of acute abdomen disease caused by abdominal angiostrongyliasis is reported. a 42-year-old otherwise healthy patient presented with a complaint of nine days of abdominal pain, constipation, disury, fever and right iliac fossa palpable mass. exploratory laparotomy was performed. after surgical treatment the patient presented serious complications. | 2005 | 16553328 |
| [an inspiration from the outbreaks of angiostrongyliasis cantonensis]. | | 2005 | 16562465 |
| [studies on susceptibility of pomacea canaliculata of different developmental stages to infection with angiostrongylus cantonensis]. | objective to study the susceptibility of pomacea canaliculata of different developmental stages to angiostrongylus cantonensis infection. | 2005 | 16562474 |
| [survey on the current status of important human parasitic infections in fujian province]. | to understand the prevalence of important human parasitic diseases in fujian province. | 2005 | 16562479 |
| [two cases of angiostrongyliasis cantonensis]. | | 2005 | 16566223 |
| association of plasminogen activators and matrix metalloproteinase-9 proteolytic cascade with blood-cns barrier damage of angiostrongyliasis. | blood-central nervous system (blood-cns) barrier breakdown, an important pathophysiological event in meningitis, results in extravasation of leucocytes into subarachnoid space. the blood-cns barrier disruption is mediated by primarily two enzyme systems, the plasminogen activators (pas) and matrix metalloproteinases (mmps). the present study showed that the activities of tissue-type pa (tpa), urokinase-type activator (upa) and mmp-9 in cerebrospinal-like fluid (csf-like fluid) were significantly ... | 2006 | 16623755 |
| the effect of temperature on the development of angiostrongylus cantonensis (chen 1935) in pomacea canaliculata (lamarck 1822). | angiostrongyliasis cantonensis, clinically presented as eosinophilic meningitis, is a snail-borne parasitic disease. we studied the effects of different temperatures on the larval development of angiostrongylus cantonensis in the freshwater snail pomacea canaliculata. six groups of snails were infected and each group was cultured under different temperature conditions. at predefined intervals, four snails from each group were dissected to examine the larval development. the development-time curv ... | 2006 | 16670882 |
| treatment of eosinophilic meningitis with a combination of prednisolone and mebendazole. | to study the efficacy of the combination of prednisolone and mebendazole for the treatment of eosinophilic meningitis, we conducted a pilot study among thai patients with eosinophilic meningitis. patients were given a two-week course of prednisolone, 60 mg/day, and mebendazole, 10 mg/kg/day. the primary observation parameter was the number of patients who still had headaches after the two-week course of treatment. forty-one patients were enrolled in the study. four (10%) patients still had heada ... | 2006 | 16760531 |
| optic neuritis secondary to angiostrongylus cantonensis infection. | to describe a case of optic neuritis secondary to angiostrongylus cantonensis infection. | 2006 | 16766404 |
| [headache after a stay in the dominican republic]. | in a 27-year-old female german patient severe headache and wandering paresthesias appeared one week after returning from a holiday in the dominican republic. after 3 weeks of ongoing symptoms she was admitted to our hospital with the suspicion of an inflammatory or infectious disease of the central nervous system. upon admission slight stiffness of the neck, fever (38.2 c) and paresthesias of the right elbow and the right thigh were noticed. laboratory findings: cerebrospinal fluid (csf) reveale ... | 2006 | 16850382 |
| chemo-paralysis for the removal of a live intraocular worm in ocular angiostrongyliasis. | angiostrongylus cantonensis is also called the rodent lung worm. it was first discovered in 1935 by chen in rattus rattus, in canton, china. the rodent is the definitive host while infected mollusks, snails and crabs act as the intermediate hosts. humans are infected by the 3rd stage larvae, either by eating undercooked intermediate hosts or by consuming vegetables.(1) it is a delicate nematode reported in asia pacific region most commonly in south-east asia and has been reported from taiwan, th ... | 2006 | 16872350 |
| communicating hydrocephalus as a complication of eosinophilic meningoencephalitis. | the authors reported an adult patient with communicating hydrocephalus in eosinophilic meningoencephalitis. he presented with localized peritonitis and then developed eosinophilic meningoencephalitis. angiostrongylus cantonensis was the causative agent. this was confirmed by the positive serology test. his consciousness did not recover after supportive treatment. the mri of the brain showed diffuse enlargement of the ventricular system two weeks after the diagnosis was made. the parameters for h ... | 2006 | 16881436 |
| polymorphic and sex-limited phosphoglucomutase in parastrongylus cantonensis (nematoda: angiostrongylidae). | phosphoglucomutase was studied by polyacrylamide gel electrophoresis in the thailand and hawaii isolates of parastrongylus cantonensis (also known as angiostrongylus cantonensis). two loci were present. the faster-moving locus (pgm-1) was polymorphic in the hawaii isolate, represented by two alleles - the faster-moving, less common pgm-1a and the slower-moving, more common pgm-1b . it was monomorphic for the faster-moving allele pgm-1a in the thailand isolate. the slower-moving locus (pgm-2) was ... | 2005 | 16883277 |
| eosinophilic meningitis? consider angiostrongyliasis. | | 2006 | 16895272 |
| eosinophilic meningitis due to angiostrongylus cantonensis. | angiostrongylus cantonensis is a nematode parasite that inhabits the pulmonary arteries and heart of rodents. it is one of the causative agents of fatal eosinophilic meningoencephalitis in man. we present five cases of eosinophilic meningitis presumably due to infection with angiostrongylus cantonensis . all the five patients gave history of ingestion of monitor lizard within ten days of onset of symptoms. | 2006 | 16912445 |
| multi-immunodot for rapid differential diagnosis of eosinophilic meningitis due to parasitic infections. | a multi-dot enzyme-linked immunosorbent assay (elisa) was developed for the rapid and simple differential diagnosis of eosinophilic meningitis due to helminth infections. ultrafiltered, purified antigens of parastrongylus (=angiostrongylus) cantonensis, gnathostoma spinigerum and taenia solium metacestodes, the most common parasites that invade the central nervous system and cause eosinophilic pleocytosis, were dotted onto a single nitrocellulose membrane strip. antigen-coated strips, when block ... | 2006 | 16923267 |
| induction of tumour necrosis factor, interleukin-1beta and matrix metalloproteinases in pulmonary fibrosis of rats infected with angiostrongylus cantonensis. | in angiostrongyliasis, chronic parasite-induced granuloma formation can lead to tissue destruction and fibrosis. here, the histomorphology of granulomatous fibrosis and proteinase production in the lungs of angiostrongylus cantonensis-infected sprague-dawley rats were investigated. the relationship between metalloproteinases and granulomatous fibrosis was investigated following infection of each rat with 60 infective larvae. granulomata and fibrosis were marked in the lungs of rats on day 180 po ... | 2006 | 16923276 |
| chinese herbal medicine yin-chen-extract as an adjunct to anthelmintic albendazole used against angiostrongylus cantonensis-induced eosinophilic meningitis or meningoencephalitis. | the effects of albendazole and yin-chen-extract co-therapy on angiostrongylus cantonensis-induced eosinophilic meningitis in balb/c mice were evaluated. assay indicators for the therapeutic effect include worm recovery, histopathological score of the fourth ventricle, tissue-type plasminogen activator, urokinase-type plasminogen activator, matrix metalloproteinase-9, cerebrospinal fluid total protein, leukocyte counts, and proinflammatory cytokines. as a result, albendazole and yin-chen-extract ... | 2006 | 16968941 |
| [parasitic dead-end: update]. | parasitic dead-ends occur when a parasite is unable to establish a permanent interaction in an unnatural host. although the likelihood of successful reproduction by the pathogenic agent is nul, parasitic dead-end heralds capture of new parasites and therefore expansion of the host range. angiostrongyliasis due to a. cantonensis or a. costaricensis, anisakiasis, ancylostoma caninum infection, gnathostomiasis and sparganosis are undoubtedly emerging zoonoses of particular medical interest. prevent ... | 2006 | 16999036 |
| angiostrongylus cantonensis: apoptosis of inflammatory cells induced by treatment with mebendazole or/and interleukin 12 in mice. | angiostrongylus cantonensis is the major cause of human eosinophilic meningoencephalitis. icr mice were infected orally with 35 infective larvae and sacrificed at 4-14 days, 25 days or 32 days post infection (dpi) for pathological and immunocytochemical examinations. in the non-treated group, no apoptosis signal was found in the meninges or parenchyma of the brains (4-14 dpi). only a few apoptotic cells were noticed at 25 dpi (3%) and 32 dpi (10%). in the groups, the animals were given a single ... | 2007 | 17049518 |
| intraocular angiostrongyliasis: clinical findings, treatments and outcomes. | ocular angiostrongyliasis, diagnosed by identification of angiostrongylus cantonensis in any part of the eye, is a very rare manifestation. we report seven cases of intraocular angiostrongyliasis in srinagarind hospital, khon kaen university, thailand. from a total of 654 cases of angiostrongyliasis diagnosed between january 1995 and april 2005, 7 cases (1.1%) with ocular manifestations were found. four men and three women were diagnosed, with a mean age of 32.1 years (range 21-46 years). all of ... | 2007 | 17064748 |
| [diagnostic protocol for guangzhou nemathelminthiasis (draft)]. | | 2006 | 17092410 |
| [studies on the growth-development and infectivity of angiostrongylus cantonensis in dormant pomacea canaliculata]. | to study the impact of dormancy of pomacea canaliculata on the growth-development and infectivity of angiostrongylus cantonensis. | 2006 | 17094596 |
| [experimental study on compatibility of three species of freshwater snails with angiostrongylus cantonensis]. | to compare the compatibility of three species of freshwater snails, pomacea canaliculata, cipangopaludina chinensis, bellamy a aeruginosa, with angiostrongylus cantonensis. | 2006 | 17094598 |
| sicam-1 in meningoencephalitis due to angiostrongylus cantonensis. | angiostrongylus cantonensis meningoencephalitis is an emergent disease in the americas. | 2006 | 17119798 |
| elsberg syndrome with eosinophilic meningoencephalitis caused by angiostrongylus cantonensis. | a 42-year-old man was admitted to our hospital with a history of fever, headache and disorientation. his cerebrospinal fluid revealed eosinophilia and his serum had an antibody against angiostrongylus cantonensis (a. cantonensis). then, he was diagnosed as eosinophilic meningoencephalitis caused by a. cantonensis. he was treated with repeated lumbar punctures and oral prednisolone. although a symptom he had been suffering from at the time of his admission was urinary retention, this symptom disa ... | 2006 | 17170511 |
| albendazole therapy for eosinophilic meningitis caused by angiostrongylus cantonensis. | eosinophilic meningitis in humans is commonly caused by the nematode angiostrongylus cantonensis. a severe headache is the most common presenting symptom. a prospective, randomized, double-blind, placebo, controlled study was conducted to determine if albendazole was efficacious in relieving such headaches. seventy-one patients (36 and 35 in the treatment and control groups) were enrolled in the study. five patients (two and three in the treatment and control groups) were excluded from the study ... | 2007 | 17177056 |
| pcr-based detection of angiostrongylus cantonensis in tissue and mucus secretions from molluscan hosts. | angiostrongylus cantonensis is a common cause of human eosinophilic meningitis. recent outbreaks of this infection have shown that there is a need to determine the distribution of this nematode in the environment in order to control transmission. a. cantonensis is generally identified morphologically in the molluscan intermediate host by microscopic examination, which can be labor-intensive. the aim of this study was to develop a pcr-based method to detect a. cantonensis directly from molluscan ... | 2007 | 17194836 |
| low susceptibility of achatina fulica from brazil to infection with angioiylus costaricensis and a. cantonensis. | introduction of achatina fulica in brazil has led to serious concerns about its role as vector for metaiylid worms: angioiylus costaricensis and a. cantonensis. experimental infection with both parasites was performed to evaluate the potential risk for their transmission by the giant african snail. groups of 5 animals, both wild and bred at captivity were exposed at different inocula: 1, 5, and 10 x 10(3) l1 of a. costaricensis and a. cantonensis. in all groups, few snails got infected and paras ... | 2007 | 17293998 |
| eosinophilic meningitis caused by angiostrongylus cantonensis after ingestion of raw frogs. | angiostrongylus cantonensis is the most common cause of eosinophilic meningitis in humans after ingestion of raw or inadequately cooked intermediate hosts or food contaminated with infective third-stage larvae. frogs are known to be a paratenic host of a. cantonensis, but have never been reported as the infectious source of human angiostrongyliasis in taiwan. we report the first case of eosinophilic meningitis caused by a. cantonensis after ingestion of raw frogs (rana plancyi). | 2007 | 17297055 |
| biochemical and pathological evaluation of albendazole/thalidomide co-therapy against eosinophilic meningitis or meningoencephalitis induced by angiostrongylus cantonensis. | to evaluate the curative effect of albendazole/thalidomide co-therapy on eosinophilic meningitis in balb/c mice caused by angiostrongylus cantonensis. | 2007 | 17298991 |
| vascular endothelial growth factor is associated with blood brain barrier dysfunction in eosinophilic meningitis caused by angiostrongylus cantonensis infection. | vascular endothelial growth factor (vegf) is a potent vascular permeability factor and a mediator of brain edema. to assess the role of vascular endothelial growth factor in eosinophilic meningitis, vascular endothelial growth factor was measured in the cerebrospinal fluid (csf) and blood of 9 patients with eosinophilic meningitis in a cohort study. vegfcsf was detected in 8 (90%) of 9 eosinophilic meningitis patients (range, 45-2190 pg/ml) at presentation. the mean vegfcsf at presentation, 1 we ... | 2007 | 17360889 |
| [development of pcr assay for detection of angiostrongylus cantonensis in pomacea canaliculata]. | to establish a pcr assay for detecting the third-stage larvae of angiostrongylus cantonensis in pomacea canaliculata. | 2006 | 17361815 |
| [heavy infection of angiostrongylus cantonensis due to swallowing raw slugs]. | | 2006 | 17366981 |
| efficacy of curcumin therapy against angiostrongylus cantonensis-induced eosinophilic meningitis. | angiostrongylus cantonensis can invade the central nervous system, leading to human eosinophilic meningitis or eosinophilic meningoencephalitis. curcumin is a natural product which has the effects of anti-inflammation, anti-oxidation and anti-carcinogensis, while the administration of curcumin has been reported to possibly relieve the symptoms of meningitis. the present study tested the potential efficacy of curcumin in a. cantonensis-induced eosinophilic meningitis of balb/c mice. assay indicat ... | 2007 | 17381860 |
| prevalence and intensity of angiostrongylus cantonensis in freshwater snails in relation to some ecological and biological factors. | the purpose of the study was to record different intermediate hosts of a. cantonensis and to determine the infection prevalence and intensity of this parasite in freshwater snails in relation to some ecological and biological factors. the study was conducted at al-salam irrigation canal and al-abtal village (north sinai) for one year, from march 2004 to february 2005. thirteen species of freshwater snails of nine families were examined for a. cantonensis infection. six species were found infecte ... | 2007 | 17432058 |
| expansion of achatina fulica in brazil and potential increased risk for angiostrongyliasis. | the explosive introduction of the snail achatina fulica in brazil illustrates the current concern with global changes favouring dissemination of infectious diseases. the mollusc is an important host for angiostrongylus cantonensis, which occurs in asia and the pacific islands and is a causative agent for eosinophilic meningoencephalitis. in the americas there is another metastrongylid worm, an. costaricensis, that causes abdominal disease and may also be transmitted by ac. fulica. although both ... | 2007 | 17481682 |
| a souvenir from the pacific islands. | | 2007 | 17515602 |
| eosinophilic meningitis associated with angiostrongyliasis: clinical features, laboratory investigations and specific diagnostic igg and igg subclass antibodies in cerebrospinal fluid. | eosinophilic meningitis (eom) associated angiostrongyliasis mostly induced by the nematode angiostrongylus cantonensis, is a common disease with worldwide prevalence. heavy infections can lead to chronic disabling disease and even death. this study was conducted to shed light on the overall specific igg antibody response as well as the specific igg antibody subclass responses in cerebrospinal fluid (csf) of patients with eom. fifteen patients with eom associated with angiostrongyliasis were incl ... | 2007 | 17539242 |
| [cloning, prokaryotic expression and immunoreactivity evaluation of angiostrongylus cantonensis galectin]. | to construct the recombinant plasmid for angiostrongylus cantonensis (ac) galectin (gal) cdna and analyze the immunological activity of the recombinant protein. | 2007 | 17545061 |
| molecular evidence for the endosymbiont wolbachia in a non-filaroid nematode, angiostrongylus cantonensis. | wolbachia harbored by most filarial parasites, is critical to both embryogenesis and microfilarial development, and may lead to inflammation and pathogenesis in infected hosts. based on alignment of the sequences from the wsp, ftsz, and 16s rrna genes, wolbachia was demonstrated to exist in angiostrongylus cantonensis, a non-filaroid nematode. although the wsp gene may not be the best candidate for evolutionary analysis of wolbachia, this gene has been sequenced from a broader coverage of the ho ... | 2007 | 17562224 |
| [a comparative study of three methods in detecting angiostrongylus cantonensis larvae in lung tissue of pomacea canaliculata]. | to compare the efficiency of three methods, lung-microscopy, tissue homogenate and enzyme digestion in the detection of angiostrongylus cantonensis larvae from the lungs of snails. | 2007 | 17639702 |
| cerebrospinal fluid eotaxin and eotaxin-2 levels in human eosinophilic meningitis associated with angiostrongyliasis. | eosinophilic meningitis associated angiostrongyliasis (eoma) is a harmful disease of the brain and spinal cord caused by a parasitic helminth, angiostrongylus cantonensis, presenting with severe headaches and cerebrospinal fluid (csf) eosinophilia. however, the immunologic pathophysiology especially in relation to the eosinophilic inflammation is still unknown. we measured the csf concentrations of eotaxin and eotaxin-2 of 30 patients and 10 controls. the csf eotaxin and eotaxin-2 levels of the ... | 2007 | 17703945 |
| [identification and tissue localization of intermediate filament protein in angiostrongylus cantonensis]. | to identify the type of the intermediate filament (if) protein of angiostrongylus cantonensis and analyze its tissue localization. | 2007 | 17715010 |
| [changes and clinical significance of cerebrospinal fluid in 69 patients with angiostrongyliasis cantonensis]. | | 2007 | 17767834 |
| light and electron microscopic studies on two nematodes, angiostrongylus cantonensis and trichuris muris, differing in their mode of nutrition. | the morphological characteristics of the adult heteroxenous blood nematode angiostrongylus cantonensis and the adult monoxenous intestinal nematode trichuris muris were compared with special regard to the ultrastructure of their digestive systems. the small circular mouth of a. cantonensis appears sucker like. the very narrow mouth of t. muris is surrounded by three lips covered by the cuticle that extends into the buccal space. in the buccal cavity of a. cantonensis, a single tooth occurs oppos ... | 2007 | 17823832 |
| cerebrospinal fluid cytokine responses in human eosinophilic meningitis associated with angiostrongyliasis. | the levels of interleukin 5 (il5), il10, and il13 in the cerebrospinal fluid (csf) were markedly higher in 30 patients with eosinophilic meningitis associated with angiostrongyliasis (eoma) than in the controls (p<0.001). il2, il4, interferon gamma (ifngamma), and tumor necrosis factor alpha (tnfalpha) levels were not significantly different (p>0.05). il5, il10, and tnfalpha levels correlated with eosinophil levels (p=0.023, p=0.018, and p=0.005, respectively) while il2, il4, il13, and ifngamma ... | 2008 | 17928005 |
| eosinophilic meningitis in a returned traveler from santo domingo: case report and review. | we describe one case of eosinophilic meningitis (em) in a traveler returning from santo domingo, presumably caused by angiostrongylus cantonensis. treatment with mebendazole and steroids was effective. the presence of persistent headache, fever, and eosinophilia in travelers who return from developing countries should alert clinicians to the possibility of em. | 2007 | 17995537 |
| angiostrongylus cantonensis: induction of urokinase-type pa and degradation of type iv collagen in rat lung granulomatous fibrosis. | granuloma formation and subsequent fibrosis around angiostrongylus cantonensis larvae in the lungs were induced experimentally in sprague-dawley strain rats. casein zymogram analysis demonstrated that urokinase-type plasminogen activator (upa) activity was increased during lung inflammation and fibrosis. granulomatous fibrosis, type iv collagen degradation and activation of upa occur simultaneously. furthermore, the present study demonstrated that collagen avidly binds upa. immunohistochemical o ... | 2008 | 18022622 |
| [clinical observation on 25 cases of severe angiostrongyliasis cantonensis]. | to summarize the clinical features of severe angiostrongyliasis cantonensis (ac) patients. | 2007 | 18038807 |
| matrix metalloproteinase-2, -9 and -13 are involved in fibronectin degradation of rat lung granulomatous fibrosis caused by angiostrongylus cantonensis. | pulmonary granuloma formation and fibrosis were experimentally induced in sprague-dawley strain rats by angiostrongylus cantonensis. increased protein levels of matrix metalloproteinase (mmp)-2, -9, -13 and the imbalance between these enzymes and metalloproteinase inhibitors, tissue inhibitors of mmps (timp-1 and -2), occur during granulomatous fibrosis. activation of proteolytic enzymes (mmp-2, -9 and -13) and fibronectin degradation occur simultaneously. furthermore, the present study demonstr ... | 2007 | 18039280 |
| the small subunit (ssu) ribosomal (r) rna gene as a genetic marker for identifying infective 3rd juvenile stage angiostrongylus cantonensis. | we have developed a molecular method using pcr-direct sequencing to identify the infective 3rd juvenile stage of angiostrongylus cantonensis, a nematode parasite of rodents that can accidentally infect humans and cause eosinophilic meningitis. we demonstrate that the 5' end of the small subunit (ssu) ribosomal (r) rna gene is a suitable marker to identify a. cantonensis and distinguish it from other closely related angiostrongylus species. when the ssu rrna marker was employed on nematode popula ... | 2008 | 18061130 |
| [peculiarities of meningoencephalitis caused by angiostrongylus cantonensis in america]. | 25 years ago was first reported in cuba and in the western hemisphere an emergent disease: eosinophilic meningoencephalitis due to angiostrongylus cantonensis larvae. | 2007 | 18075991 |
| first record of a nematode metastrongyloidea (aelurostrongylus abstrusus larvae) in achatina (lissachatina) fulica (mollusca, achatinidae) in brazil. | achatina (lissachatina) fulica was introduced in brazil in the 1980s for commercial purposes ("escargot" farming) and nowadays, mainly by human activity, it is widespread in at least 23 out of 26 brazilian states and brasília, including the amazonian region and natural reserves, where besides a general nuisance for people it is a pest and also a public health concern, since it is one of the natural intermediate host of angiostrongylus cantonensis, ethiological agent of the meningoencephalitis in ... | 2008 | 18078952 |
| first record of molluscs naturally infected with angiostrongylus cantonensis (chen, 1935) (nematoda: metastrongylidae) in brazil. | seeking the identification of angiostrongylus cantonensis as a potential etiological agent of three clinical cases of eosinophilic meningitis, mollusc specimens were collected in the state of espírito santo, brazil. the snails were identified as sarasinula marginata (45 specimens), subulina octona (157), achatina fulica (45) and bradybaena similaris (23). larvae obtained were submitted to polymerase chain reaction and restriction fragment length polymorphism diagnosis. their genetic profile were ... | 2007 | 18094889 |
| angiostrongylus cantonensis: experimental study on the susceptibility of apple snails, pomacea canaliculata compared to pila polita. | six groups (15 snails/group) of pomacea canaliculata and pila polita were infected orally with 0 (control), 200, 400, 800, 1600 and 3200 first-stage angiostrongylus cantonensis larvae (l1). the respective mean+/-sd third stage larvae (l3) worm recovery 1-month post-infection (p.i.) for p. canaliculata was 0, 1.4+/-5.42 (0.7%), 0.13+/-0.35 (0.03%), 0.07+/-0.26 (0.009%), 0.07+/-0.26 (0.004%), 0, and for p. polita 0, 64.33+/-21.38 (32.25%), 115.36+/-36.82 (28.93%), 265.33+/-90.01 (33.27%), 471.33+/ ... | 2008 | 18154954 |
| association of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinase-4 in cerebrospinal fluid with blood-brain barrier dysfunction in patients with eosinophilic meningitis caused by angiostrongylus cantonensis. | to evaluate possible blood-brain barrier (bbb) dysfunction caused by matrix metalloproteinase-9 (mmp-9) and its regulation by tissue inhibitors of metalloproteinase (timps) in patients with eosinophilic meningitis caused by infection with angiostrongylus cantonensis, 40 patients and 28 controls were included in this study. concentrations of mmp-2, mmp-9, timp-1, and cerebrospinal fluid (csf):serum albumin ratios (q(alb) values) were significantly increased in patients compared with controls. how ... | 2008 | 18187780 |
| magnetic resonance imaging of eosinophilic meningoencephalitis caused by angiostrongylus cantonensis following eating freshwater snails. | angiostrongyliasis cantonensis is a worldwide-existing parasitic disease. however, the relevant reports on its radiological appearances are limited. in this study, we investigated magnetic resonance imaging (mri) features of eosinophilic meningoencephalitis in a group of consecutive patients caused by human infection with angiostrongylus cantonensis after eating freshwater snails. | 2008 | 18208669 |
| invasive freshwater snail, china. | | 2007 | 18214199 |
| distribution of eosinophilic meningitis cases attributable to angiostrongylus cantonensis, hawaii. | during november 2004-january 2005, 5 cases of eosinophilic meningitis (em) attributable to angiostrongylus cantonensis infection were reported in hawaii. to determine if this temporal clustering reflected an increased incidence, we ascertained em and a. cantonensis cases by systematic review of statewide laboratory and medical records for january 2001-february 2005 and generalized the data to population estimates. we identified 83 em cases; 24 (29%) were attributed to a. cantonensis infection, w ... | 2007 | 18217550 |
| emerging angiostrongyliasis in mainland china. | our review of angiostrongyliasis in china found that the disease is emerging as a result of changes in food consumption habits and long-distance transportation of food. enhanced understanding of angiostrongyliasis epidemiology, increased public awareness about the risks associated with eating raw food, and enhanced food safety measures are needed. | 2008 | 18258099 |
| neurological picture. eosinophilic meningitis and an ocular worm in a patient from kerala, south india. | | 2008 | 18281446 |
| comparative efficacies of albendazole and the chinese herbal medicine long-dan-xie-gan-tan, used alone or in combination, in the treatment of experimental eosinophilic meningitis induced by angiostrongylus cantonensis. | angiostrongylus cantonensis, the rat lungworm, is the principal cause of human eosinophilic meningitis or meningoencephalitis world-wide. in the present study, the efficacies of early-stage treatment with the chinese herbal medicine long-dan-xie-gan-tan (ldxgt) and albendazole, used alone or in combination, were evaluated in balb/c mice with a. cantonensis-induced dysfunction of the blood-central-nervous-system barrier and eosinophilic meningo-encephalitis. indicators of the therapeutic effect i ... | 2008 | 18318936 |
| individual serological follow-up of patients with suspected or confirmed abdominal angiostrongyliasis. | abdominal angiostrongyliasis (aa) is a zoonotic nematode infection caused by angiostrongylus costaricensis, with widespread occurrence in the americas. although the human infection may be highly prevalent, morbidity is low in southern brazil. confirmed diagnosis is based on finding parasitic structures in pathological examination of biopsies or surgical resections. serology stands as an important diagnostic tool in the less severe courses of the infection. our objective is to describe the follow ... | 2008 | 18327506 |
| eosinophilic meningitis due to angiostrongylus cantonensis in a belgian traveller. | eosinophilic meningitis is a rare clinical entity. the most frequent cause in travellers to the tropics is infection with the rat lungworm angiostrongylus cantonensis. in this report, we describe a case of eosinophilic meningitis due to infection with this nematode in a traveller who presented with slight headache, diarrhoea, general malaise and thoracic radicular pain after a trip through latin america and the fiji islands. she responded less than optimally to repeated steroid and albendazole t ... | 2008 | 18342273 |
| apoptosis in meningoencephalitis of angiostrongylus cantonensis-infected mice. | a hallmark of eosinophilic meningoencephalitis is infiltration of leukocytes into brain parenchyma and subarachnoid space infected by angiostrongylus cantonensis. apoptosis, a process that eliminates useless cells and counterbalances tissue homeostasis, is important for homeostasis of the immune system. in this study, we investigated the characteristics of cell death induced in babl/c mice infected with a. cantonensis. we observed increased expression of the apoptotic proteins, caspase-3, caspas ... | 2008 | 18472098 |
| [construction of the life cycle of angiostrongylus cantonensis in laboratory]. | to construct the life cycle of angiostrongylus cantonensis (a.cantonensis) in laboratory condition. | 2008 | 18495588 |
| treatment of angiostrongyliasis. | angiostrongyliasis, caused by angiostrongylus cantonensis, is endemic in northeastern thailand and southern and eastern taiwan and is also reported throughout the world. humans get infected by eating raw freshwater snails or other paratenic hosts. the three main clinical forms of angiostrongyliasis are: eosinophilic meningitis (eom), eosinophilic encephalitis (eoe) and ocular angiostrongyliasis. eom, the most common form, causes acute severe headache, and corticosteroid is the cornerstone treatm ... | 2008 | 18501934 |
| ocular angiostrongyliasis: clinical study of three cases. | to report three patients with ocular angiostrongyliasis who presented with a variety of clinical findings. | 2008 | 18535614 |
| cluster of eosinophilic meningitis attributable to angiostrongylus cantonensis infection in french policemen troop returning from the pacific islands. | outbreaks of eosinophilic meningitis are reported rarely, even in regions of endemic infestation with the roundworm angiostrongylus cantonensis, such as the pacific basin. we report a cluster of eosinophilic meningitis presumably attributable to a. cantonensis among french policemen returning from french polynesia. | 2008 | 18760253 |
| [epidemiological analysis on 141 cases of angiostrongyliasis cantonensis in beijing]. | to provide scientific basis for angiostrongyliasis cantonensis control and prevention in beijing. | 2008 | 18785473 |
| absence of wolbachia endobacteria in the non-filariid nematodes angiostrongylus cantonensis and a. costaricensis. | abstract: the majority of filarial nematodes harbour wolbachia endobacteria, including the major pathogenic species in humans, onchocerca volvulus, brugia malayi and wuchereria bancrofti. these obligate endosymbionts have never been demonstrated unequivocally in any non-filariid nematode. however, a recent report described the detection by pcr of wolbachia in the metastrongylid nematode, angiostrongylus cantonensis (rat lungworm), a leading cause of eosinophilic meningitis in humans. to address ... | 2008 | 18801163 |
| detection of circulating antibody of parastrongylus cantonensis in sera with eosinophilic meningitis by dot-blot elisa. | eosinophilic meningitis caused by parastrongylus cantonensis, the rat lung worm is a major public health problem in thailand. humans acquire this parasite by eating raw food containing infective parastrongyliasis is dificult to make because identification of parasite materials by biopsy or chance finding is rarely possible. | 2008 | 18839849 |
| a severe eosinophilic meningoencephalitis caused by infection of angiostrongylus cantonensis. | this paper reports a severe case of eosinophilic meningoencephalitis after infection with angiostrongylus cantonensis. | 2008 | 18840746 |
| human angiostrongyliasis. | human angiostrongyliasis caused by angiostrongylus cantonensis, a rat lungworm, has been reported globally. human infections are acquired by ingestion of raw or undercooked snails or slugs, paratenic hosts such as prawns, or contaminated vegetables that contain the infective larvae of the worm. so far, at least 2827 cases of the disease have been documented worldwide. during the past few years, several outbreaks of human angiostrongyliasis have been reported in mainland china, taiwan, and the us ... | 2008 | 18922484 |
| ocular parasitosis: a rare cause of hypertensive uveitis. | a middle-aged asian gentleman presented with four weeks' history of recurrent redness, pain and deterioration of vision in his right eye. he was diagnosed with chronic, unilateral, granulomatous hypertensive uveitis. during one of the serial examinations a single, off-white, extremely motile, thread-like worm about 15 mm long was noted in the anterior chamber. surgical retrieval of the worm was unsuccessful. the worm disappeared in the eye and was never seen again. patient suffered from chronic ... | 2008 | 18974522 |