Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [larval biology and mechanism of transmission of the filarian dipetalonema viteae]. | 1967 | 5624529 | |
| [serologic diagnosis of filariasis by immunofluorescence on sections of dirofilaria immitis and dipetalonema viteae. preliminary results bearing on 200 examinations]. | 1968 | 4890927 | |
| [studies of immunity against microfilaria of the species dipetalonema viteae krepkogorskaja 1933 in meriones libycus and in the hamster]. | 1969 | 5394221 | |
| [epidemiological study of rodent filariasis (dipetalonema viteae krepkogorskaja 1933) in iran]. | 1969 | 4391965 | |
| [serological studies of hamsters infected with dipetalonema viteae (krepkogorskaja 1933) based on an immunofluorescence method]. | 1969 | 4390866 | |
| [simultaneous serodiagnosis of bilharziasis and filariasis by indirect immunofluorescence on juxtaposed slices of schistosoma mansoni and dipetalonema viteae]. | 1970 | 4932715 | |
| morphological changes in the spermatozoa of dipetalonema viteae in utero. | 1971 | 5167881 | |
| [can dipetalonema viteae be used for the pharmacodynamic study of filaricides]. | 1971 | 5168528 | |
| ultrastructural and cytochemical studies on the sensory organelles and nervous system of dipetalonema viteae (nematoda: filarioidea). | 1972 | 4674469 | |
| quantification of infection of ticks with dipetalonema viteae. | 1972 | 5063284 | |
| [effect of dipetalonema viteae and schistosoma mansoni parasitism on the growth of experimental tumors]. | 1972 | 4116907 | |
| [use of antigenic extracts of ascaris suum for the diagnosis of filariasis by means of double diffusion. value compared with onchocerca volvulus and dipetalonema viteae antigens]. | 1972 | 4267505 | |
| the structure and development of the spermatozoon of dipetalonema viteae (nematoda: filarioidea). | 1973 | 4578995 | |
| oogenesis and fertilization in dipetalonema viteae (nematoda: filarioidea). | 1973 | 4578996 | |
| proceedings: mastomys natalensis as a host for dipetalonema viteae. | 1974 | 4856425 | |
| fate of adult dipetalonema viteae transferred intraperitoneally to jirds. | 1974 | 4474383 | |
| dipetalonema viteae in the experimentally infected jird, meriones unguiculatus. i. insemination, development from egg to microfilaria, reinsemination, and longevity of mated and unmated worms. | 1974 | 4856592 | |
| dipetalonema viteae in the experimentally infected jird, meriones unguiculatus. ii. microfilaremia in relation to worm burden. | 1974 | 4856593 | |
| comparative biochemical studies of litomosoides carinii, dipetalonema viteae, and brugia pahangi adults. | 1974 | 4856594 | |
| transmission of dipetalonema viteae by hyperparasitism in ornithodorus tartakovskyi. | 1974 | 4858005 | |
| infection of the jird, meriones unguiculatus, with the filarial worm, dipetalonema viteae: central nervous system invasion and pathology. | 1974 | 4856033 | |
| cryopreservation of infective larvae of dipetalonema viteae. | infective larvae of dipetalonema viteae produced infections in mongolian jirds (meriones unguiculatus) after storage of infected ticks (ornithodoros tartakovskyi) in the presence of dimethyl sulfoxide (dmso, 5%) for 7 or 595 days in liquid nitrogen (-196 c). infectivity of these larvae was only partially impaired. microfilaremias of test jirds were generally lower than those of control jirds given nonfrozen larvae; however, the majority of test jirds developed microfilarial counts suitable for u ... | 1975 | 1168704 |
| dipetalonema viteae: primary, secondary and tertiary infections in hamsters. | 1975 | 1168583 | |
| fractionation of a soluble somatic extract and solubilized cuticular extracts of dipetalonema viteae adult worms. | a soluble somatic preparation (ssp) of adult dipetalonema viteae was prepared. aliquots of the aqueous insoluble debris (cuticles and membranes) left after the extraction of ssp were solubilized separately with triton x-100 and lithium diiodosalicylate to yield a triton solubilized preparation (tsp) and lithium diiodosalicylate solubilized preparation (lsp), respectively. ssp was sequentially chromatographed on a series of sephadex columns, g50; then fraction 1 from g50 on g100 and finally fract ... | 1975 | 810559 |
| amyloidosis induced in hamsters by a filarid parasite (dipetalonema viteae). | amyloidosis was induced in hmasters infected with the filarial nematode parasite, dipetalonema viteae. the incidence of amyloidosis was 64% in a group inoculated with 150 larvae and 54% in the group receiving 150 larvae in each of two inoculations. amyloidosis was not seen in control animals. microfilariae probably served as the antigenic stimulus in the pathogenesis of amyloidosis, since those animals in which amyloidosis was formed had microfilaremias that were significantly greater (p less th ... | 1975 | 1239111 |
| distribution and movement of infective-stage larvae of dipetalonema viteae (filarioidea) in the vector tick, ornithodoros tartakowskyi (argasidae). | histological sections and dissection of infected ticks, ornithodoros tartakowskyi, showed that in the resting tick the 3rd-stage larvae of dipetalonema viteae were distributed in clumps throughout the hemocoel. in the biting tick, larvae moved anteriorly and congregated especially in the capitulum; and the forward migration occurred even though no blood was ingested. this suggests that the act of biting and not the ingestion of blood is the critical factor in migration. the larvae may reach the ... | 1976 | 986434 |
| a comparison of the acquired resistance to dipetalonema viteae stimulated in hamsters by trickle versus tertiary infections. | two groups of hamsters were hyperinfected with dipetalonema viteae. each of the 15 hamsters in the first group received a total of 900 larvae given in three equal doses on days 0, 150 and 250 from the start of the experiment (tertiary-infection group). each of the 20 hamsters in the second group received a total of 900 larvae given in 18 equal doses (50 larvae per dose) at 14 day intervals. thus the final dose was given on day 238 from the start of the experiment (trickle-infection group). about ... | 1976 | 945918 |
| evidence for immunodepression of syrian hamsters and mongolian jirds by dipetalonema viteae infections. | 1976 | 557249 | |
| [deviation of the life cycle of dipetalonema viteae (filarioidea)]. | dipetalonema viteae is a filarial that can evoluate among hosts zoologically broadly apart (ixodides and argasides), but always gathered from meriones burrows. its evolution is, on the contrary, blocked among most of the other ticks, particularly among ornithodoros erraticus morphologically very similar to the normal vector. our work concerns the experimental deviation of the cycle of dipetalonema viteae, with its possible adaptability in the bosom of an intermediate of fowl tropism and a perman ... | 1976 | 1037623 |
| the pathology associated with single and quadruple infections of hamsters with dipetalonema viteae. | two groups of five hamsters were each infected subcutaneously with infective larvae of dipetalonema viteae; one group received single infections, and the second group received quadruple infections. a third group of five hamsters served as controls. hamsters with primary and quadruple infections had cellular infiltrates in the liver and glomerular basement membrane thickening; these lesions were more extensive in the multiple than single infections. hyperinfected hamsters also developed subcutane ... | 1976 | 988655 |
| transmission of microfilariae and infective larvae of dipetalonema viteae (filarioidea) among vector ticks, ornithodoros tartakowskyi (argasidae), and loss of microfilariae in coxal fluid. | during studies on the acquisition and transmission of infection with the filaria dipetalonema viteae by ornithodoros tartakowskyi, it was found that young nymphs and starved medium-sized ticks feed on recently engorged larger ticks. in this manner young ticks acquired the infection with microfilariae, and the microfilariae thus taken developed normally and after 30 days of development were transmitted to a jird. ticks harboring infective larvae were able to transfer them to other engorged ticks ... | 1976 | 988155 |
| behavior of dipetalonema viteae (filarioidea) during escape from the vector tick, ornithodoros tartakowskyi (argasidae). | to determine the behavior of dipetalonema viteae in its tick vector, ornithodoros tartakowskyi, the ticks were fed on jirds at successive intervals of 30 to 35 days after a single infective blood meal, and the number of larvae passing from the tick during each bite was determined by recovery of: 1) adult worms from the jirds' tissues; 2) larvae from skin snips taken at the feeding site immediately after the bite; and 3) larvae from serum and tissue after artificial feeding through a skin-membran ... | 1976 | 986435 |
| oral transmission of brugia pahangi and dipetalonema viteae to adult and neonatal jirds. | 1976 | 943376 | |
| dipetalonema viteae: effects of hypo- and hyperthermic stress on microfilaremia in the mongolian jird, meriones unguiculatus. | 1976 | 985754 | |
| the carbohydrate metabolism of brugia pahangi microfilariae. | evidence is presented that the microfilariae of litomosoides carinii, dipetalonema viteae and brugia pahangi have an aerobic requirement for motility, but possibly not for survival. in addition, the data suggest that in an in vitro anaerobic environment, b. pahangi microfilariae ferment glucose only as far as lactate. in an aerobic environment, however, the data are consistent with a portion of glucose being dissimilated via a one step oxidative decarboxylation of pyruvate formed from glycolysis ... | 1977 | 191584 |
| [immunological diagnosis of filariosis in persons returning from tropical countries and in european and indigenous inhabitants of endemic areas (author's transl)]. | serum samples from persons who lived in areas where onchocerciasis occurred or who had filariasis were examined with the complement fixation test and the indirect hemagglutination test for the presence of antibodies against crude extracts from dirofilaria immitis, onchocerca volvulus, dipetalonema viteae, and ascaris suum. the results could be interpreted as follows: 1. the indirect hemagglutination test was more sensitive than the complement fixation test for the demonstration of antibodies in ... | 1977 | 271633 |
| dipetalonema viteae: isoelectric focusing and immunochemical studies on somatic extracts of adult worms and microfilariae. | 1978 | 95963 | |
| alteration of amicrofilaremia in dipetalonema viteae infected hamsters with immunosuppressive drugs. | dipetalonema viteae-infected hamsters with amicrofilaremic infections were subjected to immunosuppressive therapy. methyl prednisolone acetate caused the most severe recrudescence of microfilariae while cyclophosphamide caused a low level, transient microfilaremia. saline injected control hamsters remained amicrofilaremic. neither drug influenced the number of adult worms recovered at necropsy in the treated hamsters compared with control hamsters. | 1978 | 24998 |
| indirect immunofluorescence test against dipetalonema viteae in detection of filariasis in dhanbad coalmines area. | 1978 | 355136 | |
| studies on dipetalonema viteae (filarioidea) i. microfilaraemia in hamsters in relation to worm burden and humoral immune response. | the course of a primary infection with dipetalonema viteae was studied in one randomly bred and in one inbred strain of hamster. worm recovery and the duration and intensity of the microfilaraemia were analyzed and related to the humoral immune response of the host by using the indirect immunofluorescent antibody test on frozen sections of female worms, on eggs and on intact microfilariae. the inbred strain showed a greater susceptibility to the parasite. this was evidenced by high worm recovery ... | 1978 | 28654 |
| [microfilarial observation of dipetalonemia viteae using scanning electron microscopy]. | the integumental surface on the microfilaria of dipetalonema viteae was studied by scanning electron microscopy (sem) at 1,200 to 20,000 magnification. this first study only concerns microfilaria in the circulating blood of the hamster. | 1978 | 96969 |
| intrauterine development of the microfilariae of dipetalonema viteae. | the egg shell of dipetalonema viteae separated from the oolemma and became highly convoluted at an early stage of development. no second oolemma or trilaminate membrane was seen. channels containing electron dense material (thought to be nutrient material from the uterine wall) were formed between adjacent embryos. many developing embryos died. microvilli were formed by the uterine wall and developing embryos were closely apposed to these (again presumably to obtain nutrient). embryos emerged fr ... | 1978 | 566294 |
| dipetalonema viteae: in vitro blastogenesis of hamster spleen and lymph node cells to phytohemagglutinin and filarial antigens. | 1978 | 569595 | |
| [antigenic activities of eggs, egg membranes, metabolic products and hatched larvae from the uterus of dipetalonema viteae (author's transl)]. | eggs of different stages of development, egg membranes, and the fluid isolated from uterus and pseudocoelomic cavity show antigenic properties against sera from wuchereriasis- and onchocerciasis-patients in the indirect immunofluorescent test, while hatched larvae did not show any fluorescence. isolation and simple drying of these antigenic materials on microscopic slides when compared with histologically prepared antigenic material (methacrylate or cryostate-sections) proved to have quantitativ ... | 1978 | 565549 |
| primary infections of dipetalonema viteae in an outbred and five inbred strains of golden hamsters. | 1978 | 565398 | |
| dipetalonema viteae infection in hamsters: enhancement and suppression of microfilaraemia. | mature male dipetalonema viteae released a substance(s) which caused enhanced microfilaraemia in infected hamsters. in hamsters implanted with female d. viteae, the microfilaraemia of a subsequent infection was suppressed. the microfilaraemia of female worms implanted in hamsters was depressed within 5 days when the animals were given a further infection with infective larvae. | 1978 | 564018 |
| dipetalonema viteae in hamsters: effect of antiserum or immunization with parasite extracts on production of microfilariae. | 1978 | 564017 | |
| studies on dipetalonema viteae (filarioidea) 3. antibody-dependent cell-mediated destruction of microfilariae in vivo. | antibody-dependent cell-mediated destruction of dipetalonema viteae microfilariae could be demonstrated in the golden hamster using a micropore chamber technique. microfilariae were eliminated within 24 hours in chambers of 3.0 and 5.0 microm pore size when implanted into amicrofilaremic hamsters (week 30 post infection). at peak microfilaremia (week 12 post infection), only some hamsters could efficiently destroy microfilariae. in chambers with 0.3 microm pore size, microfilariae survived for m ... | 1979 | 375512 |
| on dipetalonema viteae infection of mastomys natalensis. | experimental infections were carried out with the tissue-dwelling filaria dipetalonema viteae using the argasid tick ornithodorus moubata as the intermediate and the multimammate rat mastomys natalensis (strain gra giessen) as the final host. the optimum infective dose was found to be 50 third-stage larvae, which produced patent infections and the recovery rates of adult parasites were 47.6 and 26.4% of the inoculated larvae 140 and 189 days after infection, respectively. after an average prepat ... | 1979 | 571635 |
| development of dipetalonema viteae third-stage larvae (nematoda: filarioidea) in micropore chambers implanted into jirds, hamsters, normal and immunized mice. | development of third-stage larvae of dipetalonema viteae within subcutaneously implanted micropore chambers proceeded in all hosts tested up to the fourth-stage larvae and occasionally to adolescent worms. in the jird the timing of development was comparable to a natural infection. although the mouse is an insusceptible host, larval development could take place, but was very slow. two intraperitoneal inoculations of living third-stage larvae into mice induced the production of antibodies against ... | 1979 | 575592 |
| [influence of the sex of the final host on experimental dipetalonema vitae filariosis in golden hamsters cricetus auratus (author's transl)]. | the authors have studied the influence of the sex of the host on experimental dipetalonema viteae parasitosis in golden hamsters cricetus auratus. the parasited hamsters are sacrificed fifteen days after testing for microfilarial count, and then the extent of the infestation is measured by counting the number of male worms and female worms. the average level of microfilarial count is significantly higher in male hamsters than in female hamsters. the same applies to the extent of parasitism: the ... | 1979 | 575275 |
| serum ige levels in rats infected with dipetalonema viteae l3 larvae. | serum ige levels were measured by radioimmunoassay in rats infected with various doses of l3 infective stage larvae of dipetalonema viteae. a high stimulation in total serum ige levels was found with minute doses as well as with large doses of parasite, and ige levels remained elevated for several months. no further increase in ige levels was induced by a secondary infection. | 1979 | 575082 |
| kinetics of dipetalonema viteae infections established by surgical implantation of adult worms into hamsters. | native lvg strain hamsters were infected with dipetalonema viteae by the surgical implantation of adult worms. groups of hamsters received either 50 male, 50 female, 50 male plus 50 female or 25 male plus 25 female worms per hamster. approximately 50% of the transferred worms became established in the recipient hosts regardless of the number or sex of the worms implanted. microfilaremia occurred in recipient hamsters within 1 week after the transfer of female or male plus female worms. this micr ... | 1979 | 572146 |
| comparative utilization of pyruvate by brugia pahangi, dipetalonema viteae, and litomosoides carinii. | the metabolism of pyruvate by the adult filarial parasites brugia pahangi, dipetalonema viteae, and litomosoides carinii has been compared. istopic carbon-balance studies indicate the presence of significant pyruvate dehydrogenase activity in l. carinii but little or no activity in either b. pahangi or d. viteae. in all 3 helminths, the quantities of pyruvate that were completely oxidized to co2 and water were very small. the activities of some of the tricarboxylic acid cycle enzymes of b. pahan ... | 1979 | 571909 |
| [dipetalonema viteae larva studied by scanning electron microscopy]. | if the description in the literature is based on a study with the light microscope, in this work, with electron microscope scanning, the integumental surface on the larva of dipetalonema viteae is studied at 1,500 to 50,000 magnifications. | 1979 | 575317 |
| studies on dipetalonema viteae (filarioidea). 4. passive transfer of immunity to circulating microfilariae by spleen cells. | passive transfer experiments provided clear evidence for a role of spleen cells in the immunity of hamsters against dipetalonema viteae microfilariae. 106 or more spleen cells from postpatent (amicrofilaraemic) hamsters suppressed incipient microfilaraemia in syngeneic recipients when transferred at either week 2 or week 6 of a primary infection. spleen cells from microfilaraemic donors (week 15-16 post infection) were also capable of transferring immunity against microfilariae. the spleen cell ... | 1979 | 575583 |
| glycolytic end products of the adult dog heartworm, dirofilaria immitis. | 1. adult dog heartworms remained alive and motile for 24 hr without oxygen present and with only glucose available as a substrate. 2. lactate accounted for 55% of the carbon from the 1-14c-glucose utilized in 1 hr and 14co2 for 1.9%. 3. only traces of 14c were found in glycogen and no net accumulation of acetate was demonstrated. 4. dirofilaria immitis resembles litomosoides carinii in the percent of utilized glucose appearing as lactate but is more akin to brugia pahangi and dipetalonema viteae ... | 1979 | 122581 |
| comparative evaluation of 7 helminth antigens in the enzyme-linked immunosorbent assay (e.l.i.s.a.). | 112 sera from europeans with parasitologically proven helminthiasis were tested in the enzyme-linked immunosorbent assay (e.l.i.s.a.) against 6 crude extracts of various helminths (2 of adult worms: dipetalonema viteae, fasciola hepatica; 3 of eggs: ascaris suum, toxocara canis, schistosoma mansoni; and of echinococcus granulosus scolices) and against bovine hydatid fluid. each serum was tested simultaneously at a fixed dilution of 1:160 against all antigens. extensive cross-reactions were obser ... | 1979 | 92420 |
| antigenic activity in adult dipetalonema viteae in the indirect immunofluorescent test against sera from filariasis patients--the immunofluorescent histological search for "pure" antigen. | using ifat, it has been shown that isolated egg-shells and uterine fluid of dipetalonema viteae are the most potent antigens in heterologous systems using human sera from patients infected with wuchereria bancrofti, onchocerca volvulus and loa loa, as well as in homologous systems using sera from animals infected with d. viteae. it is suggested that these antigens are unlikely to be highly species-specific, and that anatomical isolation of antigens is a necessary prerequisite to immunochemical a ... | 1979 | 394410 |
| clearance of microfilariae of dipetalonema viteae in cba/n and cba/h mice. | 1979 | 317301 | |
| dipetalonema viteae: microfilariae production in various mouse strains and in nude mice. | 1980 | 6966226 | |
| ige antibody-mediated cytotoxicity of rat macrophages against microfilaria of dipetalonema citeae in vitro. | the fischer rat develops an acquired resistance against circulating microfilariae. macrophages from the peritoneal washings of normal rats preincubated at 37 degrees c with the sera obtained from rats immune to circulating microfilariae adhered to and kill the microfilaria of dipetalonema viteae in vitro within 16 to 24 hr. no significant adherence and cytotoxicity was mediated by sera collected from animals with microfilaraemia or from normal rats. adherence of macrophages to microfilaria was a ... | 1980 | 7191359 |
| changing proteins on the surface of a parasitic nematode. | most of the organisms of the phylum nematoda are free living, but some are animal or plant parasites of major importance to man. during their life cycle all nematodes undergo a series of moults in which they shed an external cuticle, consisting of an outermost membrane-like layer of unknown composition and a series of fibrillar layers similar to collagens. because of this structure, the cuticle has been viewed as an acellular exoskeleton with rather inert molecular components. however, observati ... | 1980 | 7422005 |
| responses of lymph node cells from dipetalonema viteae--infected hamsters to xenogeneic, mitomycin-treated leukocytes. | 1980 | 6446599 | |
| anthelmintic properties of flubendazole against dipetalonema viteae in jirds. | 1980 | 7193927 | |
| studies on dipetalonema viteae (filarioidea). 5. ultrastructural aspects of the antibody-dependent cell-mediated destruction of microfilariae. | the antibody-dependent cell-mediated destruction of dipetalonema viteae microfilariae was followed by electron microscopy both in vitro and within micropore chambers in vivo. there was a correlation between the degree of adherence (1% mf with adhered cells) and the degree of microfilarial damage. polymorphonuclear leukocytes, predominantly neutrophils, seemed to be responsible for the destruction of microfilariae in vivo. an in vitro assay indicated that eosinophils also have a role as potent ef ... | 1980 | 7191155 |
| [new contribution on dipetalonema viteae. keeping adults alive in vitro. scanning electron microscope study of the development of embryos and young larvae l1 and l2]. | the adult stages of litosomosoides carinii, dirofilaria uniformis and dirofilaria immitis have been successfully maintained in vitro though microfilaria production by the worms continued only for a period of one to 18 days. in this paper we describe the results obtained in a series of experiments in which adult l1 and l2 stages of dipetalonema viteae were maintained in vitro. | 1981 | 7195784 |
| ige antibody in eosinophil- and macrophage-mediated in vitro killing of dipetalonema viteae microfilariae. | 1981 | 7195919 | |
| dipetalonema viteae (filarioidea): development of the infective larvae in micropore chambers implanted into normal, infected and immunized jirds. | 1981 | 7196613 | |
| dipetalonema viteae: response of spleen cells in experimental mouse filariasis to mitogens and antigens. | 1981 | 6972326 | |
| dipetalonema viteae: ultrastructural study on the in vitro interaction between rat macrophages and microfilariae in the presence of ige antibody. | the in vitro interaction between rat peritoneal macrophages and dipetalonema viteae microfilariae in the presence of amicrofilaraemic rat immune serum was studied by transmission electron microscopy. the probable sequence of events leading to the killing of d. viteae microfilaria by macrophages is as follows. (a) rat peritoneal macrophages in the presence of amicrofilaraemic rat immune serum adhere to the parasite surface, (b) the macrophages extend their pseudopodia around the parasite, (c) the ... | 1981 | 7193841 |
| immunogenicity of the surface of filarial larvae (dipetalonema viteae). | 1981 | 6168046 | |
| electron microscopic studies on microfilariae of dipetalonema viteae and litomosoides carinii: the occurrence of intracellular parasites after treatment with metrifonate or diethylcarbamazine. | microfilariae of dipetalonema viteae and litomosoides carinii were studied by means of electron microscopy after oral treatment of their hosts with metrifonate (3 x 100 mg/kg) or diethylcarbamazine (3 x 250 mg/kg). these dosages led to the disappearance of microfilariae from the peripheral venous blood. however, in numerous organs blood capillaries or interstitial spaces contained degenerating microfilariae. in these cases the cytoplasm of the microfilarian cells was completely lysed, whereas th ... | 1981 | 7200306 |
| dipetalonema viteae infective larvae reach reproductive maturity in rats immunodepressed by prior exposure to schistosoma mansoni or its products and in congenitally athymic rats. | 1981 | 6972836 | |
| [serological cross-reactions between echinococcus multilocularis and dipetalonema viteae infected rodents (author's transl)]. | sera from 30 e. multilocularis infected nmri-mice and 30 d. viteae infected golden hamsters were tested in the indirect fluorescent antibody (ifat) and indirect hemagglutination (iha) tests. in the ifat there were cross-reactions with all sera, but there were differences between the average titres. while filarial antisera gave higher titres in the homologous system (1:640 against 1:80), it was the opposite with echinococcus antisera (1:160 against 1:640). other differences referred to the parasi ... | 1981 | 7048667 |
| dipetalonema viteae (filarioidea): development of the infective larvae in vitro. | the development of dipetalonema viteae third stage larvae was attempted in vitro. a monophasic culture system consisting of bhk-21 medium supplemented with 10% tryptose-phosphate broth and 15% fresh jird serum allowed the growth of previously in vivo triggered larvae, but not of those isolated from ticks. the larvae could complete their third moult and grew on a fourth stage larvae up to 5 mm. this development was comparable to that observed in vivo. the presence of an irradiated hamster kidney ... | 1981 | 6118032 |
| filarial infections of mastomys natalensis and their relevance for experimental chemotherapy. | experimental filarial infections of mastomys natalensis, strain gra giessen, with litomosoides carinii, dipetalonema viteae, brugia malayi (subperiodic), and brugia pahangi were compared. mean prepatent periods of 52, 57, 107, and 73 days p.i. were observed after subcutaneous inoculation of 40, 50, 85, and 70 infective larvae of l. carinii, d. viteae, b. malayi, and b. pahangi, respectively, in the neck region. all of the l. carinii, d. viteae, and b. pahangi infected mastomys showed a regularly ... | 1981 | 6118036 |
| serum immunoglobulin and antibody levels and the passive transfer of resistance in hamsters infected with dipetalonema viteae. | clearance of microfilariae from the circulation of hamsters infected with dipetalonema viteae was demonstrated following passive transfer of serum obtained from hyperinfected hamsters. the exclusion fraction after gel filtration of this serum on sephacryl s 200 also cleared microfilariae whereas the other fractions did not. there was no clearance with serum taken during the pre-patent, patent or latent periods of singly infected hamsters. igm antibody to the microfilaria cuticle measured by the ... | 1981 | 6118039 |
| dipetalonema viteae (filarioidea): evidence for a serum-dependent cytotoxicity against developing third and fourth stage larvae in vitro. short communication. | 1981 | 6118041 | |
| ige antibodies in human onchocerciasis. application of a newly developed radioallergosorbent test (rast). | a radioallergosorbent test (rast) was developed to detect ige antibodies against adult onchocerca volvulus antigens coupled to cnbr-activated sepharose. twenty-four out of 25 (96%) onchocerciasis sera were reactive. the lower limit of sensitivity was estimated to be at approx. 3 ng/ml ige antibodies. tests of sera from patients with non-filarial helminth infections showed much less cross-reactivity with rast than with an enzyme-linked immunosorbent assay (elisa) detecting igg and igm antibodies ... | 1981 | 6118043 |
| comparison of surface iodination methods by electron microscopic autoradiography applied in vitro to different life-stages of dipetalonema viteae (filarioidea). | different states of dipetalonema viteae (males, females, microfilariae, and 3rd-stage larvae) have been iodinated in vitro under physiological conditions by chloroglycoluril, lactoperoxidase or chloramine t. the concentrations of the catalysts were correlated with the viability of the worms. localization of the label with the different iodination methods had been visualized by electro microscopical autoradiography. chloroglycoluril-mediated iodination is predominantly localized on the filarial c ... | 1982 | 6927299 |
| dipetalonema viteae: extraction and immunogenicity of cuticular antigens from female worms. | 1982 | 7037442 | |
| detection of antibodies in brugia pahangi-infected cats by counter immunoelectrophoresis, indirect fluorescent antibody test and enzyme-linked immunosorbent assay. | in cats infected with brugia pahangi, antibodies first appeared against the larvae (l3), then against the adults (l5) and the microfilariae (mf). homologous antigens were better than antigens prepared from heterologous species (dirofilaria immitis, dipetalonema viteae, litomosoides carinii and onchocerca gutturosa) in detecting antibodies to b. pahangi in the infected cats by indirect fluorescent antibody test (ifat). metabolic products of l5, but not l3 or mf, of b. pahangi were antigenic and w ... | 1982 | 6760573 |
| protein composition of various developmental stages of dipetalonema viteae (filarioidea). | the protein composition of various developmental stages of dipetalonema viteae was analysed on polyacrylamide slab gels in the presence of sodium-dodecylsulphate. when the total proteins of adult male and female parasites, microfilariae, eggs, and third-stage larvae were compared, apparent qualitative similarities between mature and immature filariae were observed. however, several stage specific components were also identified. | 1982 | 6890965 |
| complement-mediated leukocyte adherence to infective larvae of dipetalonema viteae (filarioidea): requirement for eosinophils or eosinophil products in effecting macrophage adherence. | the present study reports the existence of c-mediated adherence of eosinophils and/or macrophages to filarial infective larvae of dipetalonema viteae. c3 molecules are present on the surface of the parasite, as shown by immunofluorescence studies. samples of fnrs depleted of ap of complement by treatment with zymosan a or of factor b by heating at 50 degrees c for 20 min fail to mediate cell adherence to the parasite. in contrast, fnrs inactivated for cp of complement by the chelating agent egta ... | 1982 | 6889619 |
| detection of ige antibodies in onchocerciasis. possibility of using allergens from dipetalonema viteae extracts that cross-react with allergenic determinants in crude extracts of onchocerca volvulus. | the present study reports the presence of onchocerca volvulus specific ige in the sera obtained from onchocerciasis patients. about 70% of onchocerciasis patients showed a raised level of o. volvulus specific ige compared to patients infected either with other human filarids (loa loa, wuchereria bancrofti, brugia malayi) or with other helminths (schistosoma mansoni, ascaris lumbricoides, fasciola hepatica). the o. volvulus specific ige level was significantly higher in patients exhibiting 'gale ... | 1982 | 6187503 |
| immunocytochemical studies on dipetalonema viteae (filarioidea). | the antigenic properties of adult male and female worms of the nematode dipetalonema viteae (filarioidea) were studied by immunocytochemistry. using sera of rodents infected with this parasite, the binding of antibodies to sections of worms embedded in epon was assayed by the peroxidase-antiperoxidase (pap) technique and by light microscopy. in female worms antigen-antibody reactions were located in the uterine fluid, the inner uterus wall, the circumference of the microfilariae and in the egg s ... | 1982 | 7048672 |
| detection of filarial antibodies in malayan and bancroftian filariasis by the indirect fluorescent antibody test, using different filarial antigens. | indirect fluorescent antibody tests (ifat) using wuchereria bancrofti infective larvae as antigen had the highest positivity rates in detecting malayan and bancroftian filariasis as compared to ifat using antigens prepared from 5 other animal filarial species, brugia pahangi, dirofilaria immitis, dipetalonema viteae, litomosoides carinii and onchocerca gutturosa. this study also recommends the use of human filarioids as the source of antigen in serological tests. however, before b. malayi and es ... | 1982 | 7051338 |
| efficacy of the avermectins against filarial parasites: a short review. | the avermectins are macrocyclic lactones produced by streptomyces avermitilis. one of them has been chemically modified and given the non-proprietary name ivermectin. the compounds have shown efficacy against various stages of filarial parasites. with respect to pre-adult stages in the mammalian host, activity has been observed against dirofilaria immitis in ferrets and dogs, and dipetalonema viteae and litomosoides carinii in jirds (meriones); but activity has not been observed against the deve ... | 1982 | 7051527 |
| transplacental transfer of rodent microfilariae induces antigen-specific tolerance in rats. | microfilariae are the smallest form in the life-cycle of filarial nematode parasites. they are released by the adult female worms and migrate through the blood and extracellular fluids where they can be transmitted by vectors. a few reports have indicated the possibility of the transmission of microfilarial infection from mother to offspring. we have infected rats with adult females of the rodent filaria, dipetalonema viteae, and report here that the transfer to d. viteae microfilaria does indee ... | 1982 | 7110358 |
| ige antibodies are more species-specific than igg antibodies in human onchocerciasis and lymphatic filariasis. | to explore the relative species specificities of the ige and igg antibody responses to helminth infections in man, we studied four pools of sera from patients infected with wuchereria bancrofti, brugia malayi, onchocerca volvulus or ascaris lumbricoides and ten individual sera from patients with onchocerciasis. ige antibodies were detected by radioallergosorbent test (rast) analysis and igg antibodies by a staphylococcus protein a radioimmunoassay (staph a-ria). analysis of the binding curves wi ... | 1982 | 7199027 |
| parasitic localization and growth in mongolian gerbil (meriones ungulicutas) infected filarial dipetalonema viteae under different lighting conditions. | 1982 | 6891006 | |
| peripheral localisation of an ige immune response at axillary lymph nodes draining the site of a local parasitic infection. | wistar-furth rats were infected subcutaneously with l3 larvae of dipetalonema viteae, filaria of meriones libycus. lymph nodes draining the site of immunization contained numerous ige-staining cells identified as lymphoid cells. in other lymphoid tissues, ige-staining cells were rare. they were absent in the lamina propria of the small intestine. these data support the view that ige lymphoid precursors are present in peripheral lymph nodes. | 1982 | 6982873 |
| uptake of adenosine 3',5'-cyclic monophosphate and isoproterenol by filarial parasites. | the filarial parasites litomosoides carinii and dipetalonema viteae both show transcuticular uptake of adenosine 3',5'-cyclic monophosphate but isoproterenol is taken up by d. viteae only. the importance of this difference is discussed from the point of view of metabolic regulation. inhibition of uptake by lectins indicates the involvement of surface sugar moieties in the transport processes. | 1983 | 6321589 |
| immunocytochemical and ultrastructural studies on dipetalonema viteae (filarioidea). | the antigenic properties of adult male and female of dipetalonema viteae were studied by immunocytochemistry. using antisera of the rodents meriones unguiculatus and mastomys natalensis infected with d. viteae, the binding of antibodies to sections of filariae embedded in epon was assayed by the peroxidase-antiperoxidase (pap) technique and by electron microscopy. the optimal staining intensity was obtained with an antiserum dilution of 1:5000. control sera were obtained from sex and age matched ... | 1983 | 6348150 |
| lysosomal enzyme in mastomys natalensis during dipetalonema viteae infection. | activities of certain acid hydrolases (viz. acid phosphatase, beta-glucosidase, beta-galactosidase, n-acetyl-beta-d-glucosaminidase and cathepsine) of post mitochondrial fraction of liver and spleen were studied during the course of dipetalonema viteae infection in mastomys natalensis. the values are significantly higher from prepatent to patent phase of infection as compared with normal animals. however, a decrease in the activity of hepatic acid phosphatase and n-acetyl-beta-d-glucosaminidase ... | 1983 | 6415875 |
| detection of ige antibodies in onchocerciasis using a semi-purified fraction from dipetalonema viteae total antigen. | a dipetalonema viteae extract was separated by gel filtration on aca 34 ultrogel into four fractions (a, b, c and d). the allergenic activity of the d. viteae extract and its various fractions was assayed by the passive cutaneous anaphylaxis (pca) test in rats using mouse sera obtained from balb/c mice transplanted with d. viteae. the pca reaction showed that fraction b was the most potent allergenic fraction of the d. viteae extract. by the radioallergosorbent test (rast) the use of fraction b ... | 1983 | 6600714 |
| liver cirrhosis in hamsters infected with dipetalonema viteae. | 1983 | 6681744 | |
| dipetalonema viteae (nematoda: filarioidea): culture of third-stage larvae to young adults in vitro. | infective third-stage larvae of dipetalonema viteae (nematoda: filarioidea) were cultured to young adults in a cell-free culture system. third-stage larvae from the tick vector grew, developed, and molted twice in a medium containing nctc 135 and iscove's modified dulbecco's medium supplemented with fetal bovine serum under a gas phase of 95 percent nitrogen and 5 percent carbon dioxide. the availability of such a culture system for filariids should facilitate studies of their immunology, bioche ... | 1983 | 6682998 |
| cryopreservation of third-stage larvae of brugia malayi and dipetalonema viteae. | methods are described for the cryopreservation of third-stage larvae of brugia malayi. optimum conditions utilized larvae free from the mosquito host frozen at the rate of -1 degree or -0.8 degrees c per min in medium containing 9% dimethyl sulfoxide and 0.004 m polyvinylpyrrolidone. nonfrozen or thawed larvae were inoculated intraperitoneally into jirds (meriones unguiculatus), the thawed larvae after cryogenic storage for 5-378 days. in general, the percentage of adult worms recovered at necro ... | 1983 | 6683940 |