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the cellular and humoral immune response to schistosoma mansoni infections in inbred rats. iii. development of optimal protective immunity following natural infections and artificial immunizations. 1978679277
[influence of the cryopreservation at nitrogen temperature on the vaccinic ability of the "pf" strain of trypanosoma cruzi (author's transl)].the cryopeservation of the "pf" strain of t. cruzi at -196 degree c has not changed its effectiveness in protecting mice against a posterior infection with a virulent trypanosoma cruzi strain. the cryopeservation technique utilized seems to be efficient and of practical and rapid examination.1978684265
quantitative aspects of the migration and evolutive asynchronism of schistosoma mansoni in mice. 1978684324
schistosoma mansoni: identification of chemicals that attract or trap its snail vector, biomphalaria glabrata.a new bioassay for chemical attractants of aquatic snails demonstrated that biomphalaria glabrata could be attracted to or trapped in the vicinity of homogenates of lettuce. fractionation of homogenates revealed the amino acids glutamate and proline and the primary attractants. attraction was specific for the l form of glutamate. proline appeared to stimulate reproductive activity. glutathione, gamma-aminobutyric acid, and a number of other compounds had no effect. extracts of lyophilized snail ...1978684418
the schistosoma haematobium egg granuloma. 1978679279
susceptibility of bahian population of biomphalaria glabrata to an allopatric strain of schistosoma mansoni.seventeen populations of snails (biomphalaria glabrata) from the state of bahia, brazil were studied with respect to their susceptibility to infection with an allopatric strain of schistosoma mansoni. two of the populations were from the city of salvador, 3 from other sites in bahia, and 12 from habitats in the municipio castro alves. our data show that the bahian snail populations are extremely variable in their susceptibility to an allopatric strain of s. mansoni and that the phenomenon is not ...1978686244
schistomsoma mansoni: phospholipid nature of the "agglutinin". 1978680078
an automatic method for recording the emergence of cercariae of schistosoma mansoni from the snail biomphalaria glabrata.in order to study the pattern of emergence of trematode larvae from the snail hosts (s. mansoni from b. glabrata) an automatic apparatus was developed. this apparatus allows the snails, each suspended by a thread, to be transported at intervals of at least half an hour into different beakers into which the cercariae are shed. this "eclosion clock" is essentially a carriage driven on perlon wheels along steel bars.1978695822
ultrastructural changes in the body wall of schistosoma mansoni during the transformation of the miracidium into the mother sporocyst in the snail host biomphalaria pfeifferi.the ultrastructure of the body wall of the free miracidium of schistosoma mansoni and the changes occurring within 48 h after penetration into the intermediate host biomphalaria pfeifferi are described. within 2 h after penetration the ciliated plates are shed into the haemolymph of the snail and phagocytized by amoebocytes. at the same time the narrow ridges between the plates of the free miracidium expand to form the continuous outer layer of the sporocyst. within 48 h the entire tegumental st ...1978695828
evaluation of oral therapy of mansonial schistosomiasis in the sudan using single and multiple doses of hycanthone and oxamniquine drugs. 1978682120
schistosomiasis presenting with testicular enlargement in elderly male.an eighty-eight-year-old puerto rican presented with painless enlargment of one testicle which proved histologically to be due to schistosoma mansoni. intratesticular ovum deposits were not associated with inflammation, granulomas, or infarction, but marked sclerosing periorchitis was present. the case illustrates a very rare form of presentation of schistosomiasis which should be considered in the differential diagnosis of unilateral testicular enlargement in patients from an endemic area, desp ...1978685010
faecal extract attracts copulating schistosomes. 1978697447
circulating antigens and immune complexes in schistosoma mansoni-infected rats. characterization by radioimmunoprecipitation-peg assay (ripega).circulating schistosome antigens (csa) and circulating immune complexes (clc) were investigated in rats infected with schistosoma mansoni. the radioimmunoprecipitation-polyethylene glycol (peg) assay (ripega), with 125i-labelled anti-s. mansoni anti-serum, detected csa during two distinct periods of the infection; the first between the 11th and the 14th week of infection and the second between the 11th and 14th week after infection. the ch50 deviation test revealed the presence of cic in sera fr ...1978688695
a filtration method for schistosome egg quantification. 1978697446
hycanthone therapy in selected patients with s. mansoni and s. haematobium infections in the sudan.the results of a clinical trial of hycanthone in 601 selected sudanese patients with s. mansoni and s. haematobium infections are reported. hycanthone was given as a single intramuscular injection at a dose of 3.0 mg per kilogramme body weight. the commonest side effects were nausea and vomiting which occurred in 35 per cent and 32 per cent respectively. no incidence of acute hepatic damage and no deaths were encountered. about one third of patients reported for follow-up. cure rate for s. manso ...1978702619
cercaricidal activity of some essential oils of plants from brazil.extended screening tests on the cercaricidal activity of various plants from northeast brazil have shown that the extracts of the leaves and fruits of piper marginatum, protium heptaphyllum, and capsicum annuum show a remarkable effect on the cercaria of schistosoma mansoni. in the case of the oils of piper marginatum and capsicum annuum, 90--96% of the cercaria of schistosoma mansoni were killed within 15 min. according to the nmr spectra, the active principles of the extracts seem to be water- ...1978703849
hepatic fibrosis in schistosomiasis: egg granulomas secrete fibroblast stimulating factor in vitro.cytosol extracts and culture supernatants of isolated egg granulomas obtained from livers of mice with schistosoma mansoni infection stimulated fibroblasts to incorporate tritiated thymidine and to proliferate in vitro. this finding suggests that hepatic granulomas may play a role in regulating hepatic fibrosis in schistosoma mansoni infections.1978705337
sewage stabilization pond: the effects on schistosoma mansoni transmission.the "facultative" sewage-stabilization pond was investigated with respect to transmission of s. mansoni. the results of field and laboratory experiments suggest that the ecologic factors i.e., physical and chemical play important roles in a combined interplay affecting the hatchability of s. mansoni eggs, infectivity of miracidia of s. mansioni and the potential existence of the planorbid snails host, b. glabrata. the results seem to indicate the successful reduction of s. mansoni transmission i ...1978705415
schistosoma mansoni: evidence for a role of serum factors in protecting artificially transformed schistosomula against antibody-mediated killing in vitro.artificially transformed schistosomula of schistosoma mansoni develop a consistent but small protection against the lethal effects of antibody plus complement when cultured for 24 h in a chemically defined medium. in contrast, they become rapidly resistant to antibody plus complement, when cultured in the presence of a complex medium consisting of equal parts of heat-inactivated rabbit serum and earle's/lactalbumin or in defined medium supplemented with small amounts of heat-inactivated rabbit s ...1978704150
[schistosomal maculitis]. 1978704031
population dynamics of snail infection by miracidia.the essential biological features of snail infection by miracidia are incorporated into a simple model which describes the rate of change with respect to time of the number of miracidial infections/host. the model is based on the assumption that the net rate of infection is directly proportional to the density of both miracidia and hosts. empirical evidence is provided to support this assumption. the basic framework of the model is expanded to take into account demographic stochasticity in infec ...1978704149
peripheral lymphocytes in patients with intestinal schistosomiasis mansoni. 1978705850
effect of praziquantel on the free living stages of schistosoma mansoni.the effect of the new schistosomicide praziquantel (2-cyclohexyl-carbonyl-1,2,3,6,7,11 b-hexahydro-2h-pyrazino[2,1a]isoquinolin-4-one) on the miracidia and cercariae of schistosoma mansoni was investigated. in vivo praziquantel inhibits hatching of miracidia for 24 h after administration of 500 mg/kg to infected mice. in vitro a concentration of 10 microgram/ml inhibits subsequent hatching in drug-free water. free swimming miracidia are rapidly killed by 1 microgram/ml. even 0.01 microgram/ml is ...1978706553
effect of total portal vein ligation on the maturation of schistosoma mansoni in mice. 1978708125
the acquisition and loss of antigen-specific cellular immune responsiveness in acute and chronic schistosomiasis in man.to characterize the development and evolution of cellular immune responsiveness in individuals infected with the parasite schistosoma mansoni, we studied fifteen patients with acute, subacute and chronic schistosomiasis. lymphocytes from the three acutely infected patients responded vigorously to schistosome antigens in an in vitro blastogenic assay. by contrast, cells from nine chronically infected individuals were essentially unreactive to these same antigens. patients infected for an intermed ...1978709912
[susceptibility of biomphalaria glabrata, albino variant, from belo horizonte, mg, to infestation by schistosoma mansoni, a parasite under natural conditions, of wild rodents of the vale do rio paraiba do sul, sp (brazil)]. 1978715359
[parasitological behavior of human and wild strains of schistosoma mansoni, in the vale do rio paraiba do sul, sp (brazil)]. 1978715360
[natural infection of small mammals by schistosoma mansoni, in the americana reservoir (são paulo, brazil)]. 1978715361
conversion of arginine to proline in murine schistosomiasis. 1978710852
interpretation of a stochastic model for analysis of age-specific prevalence curves in schistosomiasis. 1978711837
resistance of mice to secondary infection with schistosoma mansoni. i. comparison of bisexual and unisexual initial infections.mice receiving a unisexual primary infection with either sex of schistosoma mansoni did not develop detectable resistance to reinfection. in contrast, mice receiving a bisexual primary infection developed a high degree of resistance. the number of adult worms developing from the challenge infection was reduced, relative to controls, by 72--100% at challenge times of 6 weeks or greater.1978717639
resistance of mice to secondary infection with schistosoma mansoni. ii. evidence for a correlation between egg deposition and work elimination.mice reinfected with schistosoma mansoni 6--8 weeks after a primary infection largely or completely eliminated the second infection prior to the 7-week adult worm stage. in contrast, challenge worm counts were not lower than controls at the 6-day lung schistosomulum stage. at reinfection intervals of 12 or more weeks, worm counts were reduced at both stages. the reduction in lung schistosomulum count was proportional to the number of schistosome eggs present in the lungs, with no significant red ...1978717640
schistosoma mansoni distribution in ethiopia: a study in medical geography. 1978718300
a benzodiazepine derivative and praziquantel: effects on musculature of schistosoma mansoni and schistosoma japonicum.the benzodiazepine derivative (ro 11-3128) which has central nervous effects similar to other benzodiazepines, and praziquantel (pz), are two new antischistosomal drugs. at low concentrations these drugs will produce a marked spastic paralysis of male schistosoma mansoni musculature. an analysis of the action of these drugs on the parasite's musculature shows that ro 11-3128 and pz produced a rapid rise in the tension of the musculature of male schistosomes. various compounds known to interact w ...1978714190
[typhoid fever at bangui (centrafrican empire). 100 cases]. 1978719847
factors affecting the acquisition of resistance against schistosoma mansoni in the mouse. i. demonstration of resistance to reinfection using a model system that involves perfusion of mice within three weeks of challenge.the degree of resistance acquired by schistosoma mansoni-infected mice against homologous challenge has been determined by perfusion of the animals within three weeks of the challenge, at which time the challenge-derived organisms were morphologically distinguishable from the primary infection which induced the resistance. the method has been compared with assays based on determination of the number of organisms migrating through the lung, and with perfusions at a later time when the challenge h ...1978722037
factors affecting the acquisition of resistance against schistosoma mansoni in the mouse. 2. the time at which resistance to reinfection develops.mice developed a partial resistance against homologous challenge with schistosoma mansoni as early as two weeks after primary infections of 35 to 75 cercariae, and the degree of protection increased to an apparent maximum by 6 weeks. animals given a primary infection of only 25 cercariae required a longer period to acquire maximum resistance.1978722038
the influence of physical factors on the behaviour and infectivity of miracidia of schistosoma mansoni and s. haematobium. iii. effect of contact time and dispersion in static and flowing waters.the scanning and infective capacity of schistosoma mansoni and s. haematobium miracidia were tested under limited exposure times in small volumes of water, and under increasing mutual dispersion in vessels of different sizes also over increasing horizontal distances, and under different flow rates of water. it was found that the miracidia of both species retained their infective capacity for up to 1 hour in the presence of susceptible snails. the infection rates decreased with decreasing miracid ...1978722043
rat mast cell-eosinophil interaction in antibody-dependent eosinophil cytotoxicity to schistosoma mansoni schistosomula.the involvement of igg2a antibodies and mast cells in antibody-dependent eosinophil cytotoxicity suggested a possible interaction between mast cells and eosinophils for in vitro killing of schistosoma mansoni schistosomula. cell purification procedures showed that a minimum ratio of mast cells was required to obtain eosinophil cytotoxicity. the incubation of mast cells with heat-aggregated igg2a immunoglobulins before addition to a mast cell-depleted eosinophil population induced a significant d ...1978722083
the use of the radioimmunoprecipitation-peg assay (ripega) to quantify circulating antigens in human and experimental schistosomiasis.a new procedure, the radioimmunoprecipitation-peg assay (ripega) is proposed for the quantitation of total circulating schistosome antigens (csa) and circulating antigen '4' in patients, mice and rats infected with schistosoma mansoni. this sensitive and reproducible method was performed by incubation of [125i]anti-s. mansoni rabbit antibodies (for the detection of csa) or [125i]anti-antigen '4' antibodies (to detect antigen '4') with sera. separation of free from complexed antibodies was achiev ...1978722095
the effect of assay conditions on the recovery of schistosomula from the lungs of normal and resistant rats infected with schistosoma mansoni.the recovery of schistosomula from lungs of normal and resistant sprague-dawley and fischer rats was analyzed by varying the assay conditions. the effects of incubation medium, incubation time, and perfusion procedure on yields of schistosomula were significant and additive. optimal assay conditions were established to recover schistosomula by the lung recovery assay. differences were observed in the number of schistosomula recovered from lungs of normal and resistant rats; the assay was perform ...1978722454
differential susceptibility of biomphalaria tenagophila populations to infection with a strain of schistosoma mansoni.experiments to determine the susceptibility of biomphalaria tenagophila from 20 localities over the species range exposed to a strain of schistosoma mansoni showed widely varying infection rates, from 0% to 91.5%, this latter having been observed in a sample from an area where the natural infection rate of b. tenagophila has been the highest in the country. comparison with similar studies involving b. glabrata seems to indicate that a process of adaptation between s. mansoni and b. tenagophila i ...1978722455
different species and geographic strains of biomphalaria as hosts for schistosoma mansoni (saudi arabia strain). 1978722466
changes in tegumental surface of schistosoma mekongi voge, bruckner, and bruce 1978, in the mammalian host. 1978722467
schistosoma mansoni and s. haematobium infections in egypt. iv. hepatic lesions.we performed 400 consecutive autopsies in cairo, egypt. the intensity of schistosome infection in these cases was measured by counting adult worms recovered by perfusion and dissection and by counting eggs in the tissues of infected cases. symmers' clay pipestem fibrosis of the liver was clearly related to the presence and intensity of schistosoma mansoni, but not s. haematobium, infection. morphologic findings in cases with symmers' fibrosis were comparable to those in brazilian cases, and the ...1978717638
size and shape analysis of schistomsome egg-counts in egyptian autopsy data.we study egg-counts from a series of egyptian autopsy cases with active schistosomiasis at death (kamel, cheever, elwi, mosimann and danner 1977). the data are unique, and enable us to study the proportional distribution of eggs among various organs in relation to infection intensity for two species of schistosome worms. we develop a model for the distribution of eggs in three organs of the mesenteric circulation. under a lognormal distribution assumption, several exact statistical procedures ar ...1978719118
immunopathologic mechanisms in parasitic infection with emphasis on schistosomiasis. 1978725651
parasitological and ecological aspects of schistosomiasis mansoni in the valley of the paraíba do sul river (são paulo state, brazil) i. natural infection of small mammals with schistosoma mansoni.small mammals naturally infected with schistosoma mansoni were studied in the valley of the paraíba do sul river (são paulo state, brazil). 192 animals of 12 species were examined post mortem. cavia aperea, holochilus brasiliensis leucogaster, nectomys squamipes squamipes, oryzomys nigripes eliurus and zygodontomys brachyurus were found infected. most schistosome eggs found in the faeces were mature but no eggs were found in the faeces of c. aperea although adults were recovered. in the other in ...1978725994
circumoval precipitin test in the prepatent and acute phases of human schistosomiasis mansoni infection. 1978726008
the oogram as a sensitive method of assessing the effect of dietary deficiency on the parasite in experimental schistosomiasis mansoni.effects of malnutrition on schistosoma mansoni worms harbored by groups of chronically infected malnourished mice were assessed by four different methods: oogram technique, liver egg count, measurement of worm lengths and the number of surviving worms. compared with the other methods the oogram technique showed several advantages. it seems to be the method of choice for conducting such studies at the chronic stages of the disease. unlike other methods each of which offers only one parameter of m ...1978726035
epidemiology of poly-parasitism. iv. combined effects on the state of health.the assessment of morbidity caused by chronic parasitic infections in the populations of endemic areas has remained difficult and controversial. contributing to this predicament is the frequent occurrence of multiple infections with agents that can cause a wide range of clinical manifestations, from the frequent symptomless carrier state to overt disease with more or less specific clinical manifestations. in the interpretation of the complex morbidity patterns found in rural populations of tropi ...1978726041
serum immunoglobulin concentrations in human s. mansoni and s. haematobium infections in the sudan, with special reference to the effect of chemotherapy.the serum immunoglobulin concentrations of igg, iga and igm were studied in 111 selected sudanese patients with s. mansoni infections and 48 with s. haematobium infections before and 6 weeks after successful treatment with hycanthone; 52 local individuals were studied as controls. both igg and igm were found to be significantly raised in s. mansoni patients compared with controls, while only igg was significantly raised in patients with s. haematobium infection. s. mansoni patients with the hepa ...1978726042
humoral immune responses in human hepatosplenic schistosomiasis mansoni.the development of hepatosplenic schistosomiasis in humans cannot always be related to the intensity of infection. a study was designed to identify different humoral immunologic responses to schistosoma mansoni in patients with and without hepatosplenic disease. twenty-four patients with active hepatosplenic disease were closely matched for age, sex, and fecal egg counts with twenty-four patients with only intestinal disease. a serum sample from each of these patients was tested for antibodies t ...1978727322
recovery of the hepatic drug-metabolizing capacity in mice infected with schistosoma mansoni following curative chemotherapy with the schistosomicide 4-isothiocyano-4'-nitro-diphenylamine (cgp 4540).treatment of mice infected with schistosoma mansoni with a single oral dose of formulated 4-isothiocyano-4'-nitro-diphenylamine (cgp 4540) restored the capacity of the liver of these animals to metabolize certain drugs. full recovery required 35-40 weeks. administration of cgp 4540 to non-infected animals produced no significant changes in the activities of some hepatic drug-metabolizing enzymes.1978727323
treatment of complicated schistosomiasis mansoni with oxamniquine.twenty male patients (mean age 23 years) with schistosoma mansoni infections (mean egg count 429 +/- 311/g feces) were each treated with oxamniquine orally in a single daily dose of 20 mg/kg for 3 consecutive days. seventeen patients had hepatosplenomegaly, two of these had ascites. three patients had diffuse colonic polyposis, one of these had ascites. except for one who developed mild hematemesis 3 days after treatment, all patients tolerated the drug very well. however, 11 patients developed ...1978727334
[chaetotaxic variations of the cercaria schistosoma mansoni from a human strain during successive transmissions through mice (author's transl)].the "cercarian chaetotaxic index" from the human strain of schistosoma mansoni from west africa is conspicuously modified during the third transmission biomphalaria pfeifferi-white mouse only. this might be the explanation why planorbs collected in guadeloupe discharge slightly different cercariae whether they come from stations where the infestation is predominantly from human origin or from stations where the infestation is predominantly from murine origin. on the contrary, the "grand etang" s ...1978727643
schistosomiasis in saudi arabian recruits. a morbidity study based on quantitative egg excretion.we surveyed stool and urine specimens from 245 saudi arabian trainees for parasites. schistosoma mansoni eggs were found in the stool in 66 (26.9%) and s. haematobium eggs were recovered from the urine in 1 (0.4%). additional parasites were recovered in 167 (68.2%) of the survey group and were not more common in those with schistosomiasis (p greater than .10). schistosome egg counts ranged from 0--6,320 eggs/g feces (mean 447.9). when patients with high egg counts (over 400 eggs/g) were compared ...1978717636
re-infection of patients in schistosomiasis mansoni endemic areas after specific treatment. i--influence of age and worm burden. 1978725427
[experimental chemotherapy of schistosomiasis mansoni. schistosomicide activity of precursors of 1,4-naphthylenediamine and naphthoquinone]. 1978725424
schistosoma mansoni: complement-mediated cytotoxic activity in vitro and effect of decomplementation on acquired immunity in mice. 1978729694
schistosoma mansoni: analysis of surface membrane carbohydrates using lectins. 1978729700
demonstration of eosinophil degranulation on the surface of opsonized schistosomules by phase-contrast cinemicrography.phase-contrast cinephotomicrography was used to examine eosinophil-schistosomule interaction. eosinophil degranulation against the surface of schistosomules was observed in the presence of immune serum.1978730347
schistosoma mansoni and fasciola hepatica: cross-resistance in mice. 1978729688
schistosoma mansoni: lysozyme activity in biomphalaria glabrata during infection with two strains. 1978729698
schistosoma mansoni: purification and characterization of malate dehydrogenases. 1978729691
chemotherapy of schistosomal colonic polyposis with oxamniquine.schistosomal polyposis of the colon is a common complication of schistosomiasis. in severe infections it may be associated with considerable morbidity. surgery is associated with high morbidity and mortality. niridazole therapy is of limited therapeutic value because of its hepatotoxicity but oxaminiquine has been found to be effective and safe. several dosage regimens have been tried but a total dose of 40 mg/kg over two days in two equally divided doses has been found to have an effective ther ...1978734715
mother-child relation in human schistosomiasis mansoni : skin test and cord blood reactivity to schistosomal antigens.reaction to schistosomal antigen was studied in children born to mothers infected with schistosoma mansoni. values of immediate (15 min) skin reactions were more elevated and values of delayed (24 h) skin reactions were significantly higher in children born to infected mothers than in children born to uninfected mothers. the macrophage migration inhibition test, done on cord blood cells, was positive to schistosomal antigen in 40% of children born to infected mothers and negative in all children ...1978734716
resistance against schistosoma mansoni induced by immunization of mice with cryopreserved schistosomula. 1978734736
hemocytes of biomphalaria glabrata: factors affecting variability. 1978731071
scanning microfluorimetric studies of anticholinergic drugs in schistosoma mansoni.a microfluorimetric technique has been used to analyze fluorescence in specimens of schistosoma mansoni labeled with a dansylated analog of acetylcholine. anticholinergic drugs inhibit the fluorescent labeling of living specimens. the effectiveness of anticholinergic agents can be expressed as a fractional decrease in observed fluorescence of specimens, and several drugs have been compared in this context. atropine, eserine, carbachol and mecamylamine block fluorescence only at high concentratio ...1978731445
tropical paraplegia: a case of transverse myelitis, probably caused by schistosomiasis mansoni.in tropical regions transverse myelitis may be caused by involvement with schistosoma or the eggs of this organism. although 200 million people seem to be infected with this disease, involvement of the spinal cord is rare. a case of a 15-year-old boy is described and some literature reviewed.1978733280
the effect of hycanthone on nucleic acid synthesis by schistosoma mansoni. 1978736665
intestinal parasites of school children in urban and rural areas of eastern nigeria.from october 1975 to march 1976 an epidemiological survey was carried out in anambra and imo states of nigeria to determine the rate of intestinal worm and protozoan infections in school children. a total of 1742 children, out of which 813 from the urban and 929 from the rural school were screened of intestinal helminths and 1699 were also examined for intestinal protozoan infections. concentration methods hcl-ether centrifugation technique and heidenhain's iron-hematoxylin staining method respe ...1978735552
treatment of schistosomiasis. 1978741294
fatal hepatic necrosis in association with hycanthone. 1978741319
detection of antibodies by enzyme-immunoassay in human schistosoma mansoni infections: a clinical and chemotherapeutic study.sera from patients with s. mansoni infections, before and six weeks after successful treatment with hycanthone, were examined for antibodies reacting with s. mansoni adult worm antigen, employing the enzyme-linked immunosorbent assay (elisa) technique. 50 local individuals who had no schistosomiasis and 48 patients with s. haematobium infection were studied for comparison. all sera from untreated patients gave positive results. significantly higher levels of antibody were given by sera from pati ...1978741502
[the role of the skin surface lipids of the mouse in the "in vivo" penetration of "schistosoma mansoni" cercariae (author's transl)]. 1978742933
schistosoma mansoni worm in ovarian cystic teratoma. a case report. 1978741280
purification, immunochemical and biological characterization of malate dehydrogenase of schistosoma mansoni. 1978738760
studies on putative adult worm-derived vaccines and adjuvants for protection against schistosoma mansoni infection in mice.intraperitoneal transfer of viable adult worms of schistosoma mansoni did not confer protection against a challenge infection to recipient mice. antigens of schistosome origin were evaluated for their ability, with and without concomitantly administered nonspecific adjuvants, to stimulate protective immunity against s. mansoni. freshly perfused ground worms or a putative membrane antigen extracted with 0.5 m kc1 from adult worms, when injected together with corynebacterium parvum (or in a single ...1978739318
complement components and immunoglobulins in patients with schistosomiasis. 1978743807
effect of experimental schistosomiasis mansoni on plasma and erythrocyte lipids and on plasma lecithin: cholesterol acyltransferase in the mouse. 1978746187
lecithin:cholesterol acyltransferase deficiency associated with hepatic schistosomiasis mansoni.plasma and erythrocyte lipid abnormalities occur in chronic human schistosomiasis mansoni and appear to be related to mild lecithin:cholesterol acyltransferase (lcat) deficiency. plasma lcat activity is about 50% lower than normal in decompensated hepatosplenic schistosomiasis, whilst the plasma concentrations of cholesteryl ester and lysolecithin and decreased and that of lecithin increased in the earlier hepatointestinal and compensated hepatosplenic forms of the disease as well as in the late ...1978746348
ecological studies in madagascar of biomphalaria pfeifferi, intermediate host of schistosoma mansoni. 2. biology and dynamics in the non-endemic area of antananarivo.the region of antananarivo, where schistosomiasis is not yet endemic, is compared to ambositra, a well established focus of s. mansoni, with regard to climate, hydrology and snail habitats. higher mean temperatures and a more pronounced dry season in antananarivo contribute to sometimes less favourable hydrological conditions. biomphalaria is found in very few and limited habitats. population dynamics were followed up in selected habitats and showed ecological parameters comparable to those of t ...1978747438
[pseudo-tumoral manifestations of schistosoma-mansoni bilharziasis observed on madagascar. 93 cases].concerning respectively 93 observations got in the laboratory of "pathology" of the institut pasteur (from 1954 to 1976) and the laboratory of "pathology" of the hospital of befelatanana, tananarive (from 1960 to 1975) the authors would like to point out to the medical doctors the pseudo-tumoral aspects of the bilharziasis due to schistosoma mansoni. 1(0) the pseudo-tumoral aspects of the intestinal bilharziasis are relatively seldom complications of this parasitosis. 2(0) the malignant macrosco ...1978743776
migration of the schistosomula of schistosoma mansoni from skin to lungs. 1978748837
ultrastructural evidence for complement and antibody-dependent damage to schistosomula of schistosoma mansoni by rat eosinophils in vitro. 1978748839
relationship between a species of malaysian nematode daubaylia and the schistosome intermediate host biomphalaria glabrata. 1978749232
[molluscicidal properties of the euphorbia cotinifolia l (author's transl)].the hexanic extract from the leaves of euphorbia cotinifolia l. has been experimentally used as molluscicide against biomphalaria glabrata. the extract was fractionated and the most actives fractions were those of numbers 6 and 7. the lethal concentrations (lc50 and lc90 obtained using fraction 6 against adult snails were 1,2 and 2,4 ppm; for the eggs they were 25,0 and 48,0 ppm. with fraction 7 the lethal concentrations were 1,4 and 3,4 ppm for adult snails; for newly hatched snails they were 4 ...1978751112
[susceptibility of a strain of biomphalaria glabrata from venezuela to infection with 2 different strains of schistosoma mansoni]. 1978751168
[influence of hyperglycemic diet and of alloxan diabetes on the vitality of schistosoma mansoni sambon, 1907, in experimentally infected mice]. 1978751172
[some aspects concerning the study of strains of schistosoma mansoni sambon, 1907, originating from the states of minas gerais and são paulo, brazil]. 1978751173
the mechansim of antibody-dependent, eosinophil-mediated damage to schistosomula of schistosoma mansoni in vitro: a study by phase-contrast and electron microscopy.a characteristic sequence of events has been identified by phase-contrast and electron microscopy during antibody-dependent, eosinophil-mediated damage to schistosomula of schistosoma mansoni in vitro. human eosinophils initially adhere to the intact schistosomulum and then, in the presence of antibody, flatten and spread very intimately over the parasite's surface. subsequently, dense material similar to the contents of the lysosomal granules of the eosinophils appears in the extracellular spac ...1978748337
investigations into the control of schistosomiasis at the hva wonji-shoa sugar estates in ethiopia. 2. interim evaluation of the project. 1978744187
rodents as laboratory hosts for schistosomes.the rodent species used at the south african institute for medical research for the culture of mammalian species of schistosomes are listed. emphasis is given to the advantages of wild south african species which have been adapted to laboratory conditions, and infection techniques are discussed.1978745203
a study of the relationship between the energy contents of schistosoma mansoni cercariae and their death during penetration of mammalian host skin.immersion of biomphalaria pfeifferi in 1.5% glucose solution showed that the snails did not absorb any glucose during the first six hours but that almost 30% of the glucose was absorbed after 24 hours. the glycogen content of such "glucose-fed" snails was much higher than that of control normal snails. cercariae of s. mansoni collected from the former snails exhibited a much lower level of death (20%), during penetration of mouse skin, than that of control normal cercariae (36%). it is suggested ...1978752056
schistosoma mansoni: the activity and development of the schistosomulum during migration from the skin to the hepatic portal system. 1978756526
mannosyl transferase activity in homogenates of adult schistosoma mansoni.homogenates of adult schistosoma mansoni contain enzymes which are capable of transferring [14c]mannose from gdp[u-14c]mannose to a lipid acceptor which migrates as a single peak on a silica gel thin-layer plate. this lipid may belong to the class of polyprenol monophosphates which are intermediate elements in the glycosylation of nascent proteins. the schistosome mannosyl transferase activity is associated with membranous particles and is dependent on the presence of mn2+. however, other divale ...1978756527
[the "elisa" assay in the immunological diagnostic of s. mansoni (author's transl)]. 1978757725
homologous immunity in schistosomiasis mansoni using ultra-violet irradiated cercariae. 1978752052
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