Publications

TitleAbstractYear(sorted ascending)
Filter
PMID
Filter
effects of ph and temperature on the wild-type and a mutant form of neurospora glutamate dehydrogenase.1. we confirm the observation of bürk (1965) that neurospora crassa nadp-linked glutamate dehydrogenase normally exists in an inactive form below ph7.0 and in a fully active form above ph8.0 in either tris or orthophosphate buffer. at ph7.4 the enzyme is about half activated at 25 degrees . 2. the variety of the enzyme produced by the mutant am(2l) shows a similar behaviour except that the transition is shifted about one ph unit in the alkaline direction. 3. the am(2l) enzyme has previously been ...19676049385
altered protein formation as a result of suppression in neurospora crassa.the mutant td201 of neurospora crassa is mutated in the trp-3 locus and forms an altered tryptophan synthetase. a suppressor mutation, su2-6, in this mutant, unlinked to the trp-3 locus, results in the production of wild-type tryptophan synthetase activity, which accounts for the alleviation of the tryptophan or indole requirement. this enzyme activity is associated with a protein physically dissimilar to the wild-type enzyme. a second altered protein, a serologically cross-reacting material is ...19676025305
phenotypic reversal by 5-fluorouracil of the auxotrophy of am mutants of neurospora crassa. 19676036856
synchronous production of conidiophores and conidia of neurospora crassa. 19676039196
evidence for multiple forms of isocitrate lyase in neurospora crassa.the effect of carbon source on isocitrate lyase formation was studied in a wildtype strain of neurospora crassa and in a uridine-deficient mutant. a constitutive level of the enzyme was produced in a casein hydrolysate medium. the enzyme was repressed by glucose, although the two strains varied with respect to the degree of glucose repression. acetate strongly stimulated isocitrate lyase formation. the enzyme formed in the presence of acetate differed in several respects from that formed in gluc ...19676025448
inheritance of growth rate in neurospora crassa: reverse selection in an improved strain. 19675235104
[ribonucleases, phosphodiesterases and phosphomonoesterases in the culture of neurospora crassa under various conditions]. 19674294145
studies on the fungitoxicity of captan. v. electron microscopy of captan-treated neurospora crassa conidia. 19676041105
the purification and properties of histidinol dehydrogenase from neurospora crassa.1. a procedure is described for the purification of l-histidinol dehydrogenase (l-histidinol-nad oxidoreductase, ec 1.1.1.23) from neurospora crassa. 2. the enzyme, as purified, has a sedimentation coefficient, s(20), of 7.1s and a molecular weight of 81 000. considerable variation is possible in the state of polymerization of the enzyme, giving rise to observed molecular weights from 40 000 to 240 000. 3. several kinetic parameters of the enzyme have been determined. the enzyme is maximally act ...19676033771
inositol biosynthesis in neurospora crassa. 19674383057
effects of edta on tyrosinase and l-amino-acid oxidase induction in neurospora crassa. 19674961897
nuclear division in neurospora crassa during conidiation and germination. 19674168108
an apparent relationship between mistranslation and an altered leucyl-trna synthetase in a conditional lethal mutant of neurospora crassa. 19676038419
[uptake of the sugars sorbose, fructose and glucose by sorbose-resistant mutants of neurospora crassa]. 19674384839
sorbose transport in neurospora crassa. 19676031493
quantitative and qualitative aspects of photoreactivation of premutational ultraviolet damage at the ad-3 loci of neurospora crassa. 19676026395
[possible presence of glycerol teichoic acid in neurospora crassa]. 19675622359
[active uptake of sugars by cells of neurospora crassa in the presence of an enzymatic system with permease properties ii]. 19674384716
[active uptake of sugars by cells of neurospora crassa in the presence of an enzymatic system with permease properties i]. 19674384715
methylation of ethanolamine phosphatides by microsomes from normal and mutant strains of neurospora crassa. 19676016609
homocysteine and cysteine synthetases of neurospora crassa. purification, properties, and feedback control of activity. 19676016326
mutation-induced and nuclear inactivation in neurospora crassa using radiations with different rates of energy loss. 19676058651
the effect of nitrogen source and cysteine on the morphology, conidiation and a cell wall fraction of conidial and aconidial neurospora crassa. 19675600895
[metabolism of glycine and conidiation in neurospora crassa]. 19675591331
specificity in the photoreactivation of premutational damage induced in neurospora crassa by ultraviolet. 19675586545
[analysis of sorbose resistance in neurospora crassa in heterokaryons of sorbose resistant mutants; contribution to the genetics of active transport]. 19675586542
[crossing analysis of sorbose resistant mutants of neurospora crassa]. 19675586541
[analysis of sorbose resistance in neurospora crassa double mutants; contribution to the genetics of active transport. ii]. 19675584171
catabolite repression of malic dehydrogenase in neurospora crassa. 19676054686
enzyme activities during the asexual cycle of neurospora crassa. i. succinic dehydrogenase. 19676054680
the preparation and biochemical properties of mitochondria from neurospora crassa. 19676052632
deacetylation of n-acetyl-l-glutamic acid by neurospora crassa. 19676035272
alteration of tryptophan-mediated regulation in neurospora crassa by indoleglycerol phosphate.the accumulation of imidazoleglycerol phosphate during growth of neurospora crassa in the presence of 3-amino-1,2,4-triazole was found to cause derepression of tryptophan synthetase and to inhibit the induction of kynureninase. accumulation of indoleglycerol phosphate in response to growth in the presence of indole acrylic acid or anthranilic acid was also accompanied by derepressed synthesis of tryptophan synthetase. enzyme synthesis in mutants (his-7 and trp-4) unable to form these intermediat ...19685650070
regulation of enzyme synthesis in neurospora crassa. bnwl-714. 19685307103
the relationship of ethanol dehydrogenase to morphogenesis of neurospora crassa. 19685727908
analysis of a case of mutagen specificity in neurospora crassa. i. dose-response curves. 19685713537
biosynthesis of betaine in neurospora crassa. 19685711186
[metabolic control and ultrastructural aspects of the conidiation (macro-microcondia) in neurospora crassa]. 19685699314
kinetic studies of mutation induction by epoxides in neurospora crassa. 19685683008
a mutagenic after-effect associated with ethylene oxide in neurospora crassa. 19685683006
homology tests on presumed multilocus deletions in the ad-3 region of neurospora crassa induced by the acridine mustard icr-170. 19685656345
genetic analysis of the extent and type of functional inactivation in irreparable recessive lethal mutations in the ad-3 region of neurospora crassa. 19685656344
non-nuclear inheritance of uv sensitivity in neurospora crassa. 19685759970
the effect of cycloheximide on carotenoid biosynthesis in neurospora crassa. 19685704312
anthranilic acid as a feedback inhibitor of glutamine synthetase of neurospora crassa. 19685704311
the in vivo iron donor for haem synthesis in neurospora crassa. 19684239950
the formation of 5-formyluracil by cell-free preparations from neurospora crassa. 19684387266
induced macroconidia formation in neurospora crassa. 19685721155
[inclusion of adenine-8-c14 into the ribosomes and polyribosomes of germinating conidia and mycelium of a neurospora crassa 28610 ad. strain deficient in adenine]. 19685747531
in vivo regulation of intermediate reactions in the pathway of tryptophan biosynthesis in neurospora crassa.the in vivo regulation of intermediate reactions in the pathway of tryptophan synthesis in neurospora crassa was examined in a double mutant (tr-2, tr-3) which lacks the functions of the first and last enzymes in the pathway from chorismic acid to tryptophan. the double mutant can convert anthranilic acid to indole and indole-3-glycerol, and the production of these indolyl compounds by germinated conidia was used to estimate the activity of the intermediate enzymes in the pathway. indole-synthes ...19685726311
the exogenous environment as a factor in the control of the 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase of neurospora crassa. 19685729957
a new locus in the tryptophan pathway of neurospora crassa. 19685708292
specific inhibition by atp and other properites of an endonuclease of neurospora crassa. 19685701229
electrophoretic pattern of and amino acid incorporation in vitro into the insoluble mitochondrial protein of neurospora crassa wild type and mi-1 mutant. 196811945305
evidence for nonsense mutations in the arom gene cluster of neurospora crassa. 19685710960
c-terminal analysis of histidinol dehydrogenase from neurospora crassa. 19685679374
[mechanism of action of thiopicolinic acid anilide in neurospora crassa]. 19684237100
growth of a neurospora crassa lysine auxotroph on glutaric acid. 19685666732
the pathways of thiamine biosynthesis. separation, purification, and identification of some precursors of the pyrimidine moiety of thiamine produced by neurospora crassa auxotrophs. 19685666944
utilization of exogenous and endogenous ornithine by neurospora crassa.through the use of a mutant deficient in ornithine-delta-transaminase (ota), it is shown that this enzyme normally has no obligate or even major biosynthetic role in neurospora. the pathways of ornithine and proline synthesis proceed wholly independently of each other in ota-less strains. it is probable that ota functions as an enzyme of arginine catabolism. with mutants affected in ota, ornithine transcarbamylase, and the synthesis of ornithine, it was demonstrated that exogenous and endogenous ...19685674053
mutants of neurospora crassa deficient in ornithine-delta-transmainase.the arg-12(s) mutation of neurospora causes a partial block in the ornithine transcarbamylase (otc) reaction. strains carrying this mutation will use endogenous ornithine, but not exogenous ornithine, as a precursor of arginine. certain strains carrying arg-12(s) may be used for direct selection of variants able to use exogenous ornithine as an arginine precursor. among eight such derivatives, six lacked the catabolic enzyme ornithine transaminase (ota). all six mutations were alleles of a singl ...19685674052
regulation of "malic" isozymes and malic dehydrogenases in neurospora crassa. 19685667339
[endoplasmic reticulum and centripetal progression of the interconidial septum in a morphologic mutant of neurospora crassa]. 19685705255
a repressible alkaline phosphatase in neurospora crassa. ii. isolation and chemical properties. 19685653190
the nature of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in extracts of wild-type neurospora crassa: a reaction controlled by two activating substrates and three allosteric negative modifiers. 19684968658
genetic and complementation studies of a new carotenoid mutant of neurospora crassa. 19685699832
heterokaryotic transmission of factors affecting recombination in neurospora crassa. 19685699828
role of iron in the regulation of heme biosynthesis in neurospora crassa. 19685653647
homocitrate formation in neurospora crassa. relation to lysine biosynthesis. 19684296471
amino acid incorporation by cell-free extracts of neurospora crassa. 19685649916
chromatographic differences between the cytoplasmic and mitochondrial trnas of neurospora crassa. 19685656076
observations on the tube method of measuring growth rate in neurospora crassa. 19685652094
growth of neurospora crassa in unstirred liquid cultures. 19685652093
genetic control of aspartate transcarbamylase by the pyr-3 locus of neurospora crassa. 19685649514
a membranelike fraction from neurospora crassa, i. structure of "membranes" and release of free amino acids. 19685240019
enzyme activities during the asexual cycle of neurospora crassa. ii. nad- and nadp-dependent glutamic dehydrogenases and nicotinamide adenine dinucleotidase.three enzymes, (a) nicotinamide adenine diphosphate-dependent glutamic dehydrogenase (nad enzyme), (b) nictoinamide adenine triphosphate-dependent glutamic dehydrogenase (nadp enzyme), and (c) nicotinamide-adenine dinucleotidase (nadase), were measured in separate extracts of neurospora crassa grown in vogel's medium n and medium n + glutamate. specific activities and total units per culture of each enzyme were determined at nine separate intervals phased throughout the asexual cycle. the separa ...19684384627
control of nitrate reductase by iron in neurospora crassa. 19685661623
evidence for two types of 18-s ribosomal rna in neurospora crassa. 19685642641
[light-dependent carotenoid synthesis : iv. the role of oxygen in photoinduction].the purpose of these studies was to investigate wether the primary step in the reaction chain of the light-dependent carotenoid synthesis in heterotrophic organisms, the photochemical reaction of the photoreceptor, requires oxygen. submerged cultures of fusarium aquaeductuum and neurospora crassa were used.biosynthesis of carotenoids following a photoinduction occurred only under aerobic conditions. when the mycelia were illuminated in the absence of oxygen and subsequently transferred to aerobi ...196824515321
phenylalanine-tyrosine biosynthesis in neurospora crassa. 196817248403
somatic cell variation during uninterrupted growth of neurospora crassa in continuous growth tubes. 19685652069
tryptophan transport in neurospora crassa. ii. metabolic control.the rate of tryptophan transport in neurospora is regulated by the intracellular pool of tryptophan. when cells were shifted from growth in minimal medium to tryptophan-containing medium for 10 min, there was a 50% reduction in the rate of tryptophan transport. intracellular tryptophan pools derived from indole were equally effective in reducing the rate of transport as externally supplied tryptophan. the regulatory influence of tryptophan on the transport system appears to be a property of all ...19685643067
nature of the complementation products formed by a complementing mutant of neurospora crassa.the mutant am-14 produces no active nicotinamide adenine dinucleotide phosphate-linked glutamate dehydrogenase (gdh) and no protein showing immunological cross-reaction with the enzyme. nevertheless, it shows complementation with several other am mutants in heterokaryons. active gdh can be extracted from heterokaryons formed from am-14 and other mutants which, by themselves, produce more or less inactive varieties of the enzyme. the enzyme from am-14 + am-3 heterokaryons can be partially separat ...19685643060
acetate-nonutilizing mutants of neurospora rassa. ii. biochemical deficiencies and the roles of certain enzymes.the levels of krebs cycle, glyoxylate cycle, and certain other enzymes were measured in a wild-type strain and in seven groups of acetate-nonutilizing (acu) mutants of neurospora crassa, both after growth on a medium containing sucrose and after a subsequent 6-hr incubation in a similar medium, containing acetate as the sole source of carbon. in the wild strain, incubation in acetate medium caused a rise in the levels of isocitrate lyase, malate synthase, phosphoenolpyruvate carboxykinase, acety ...19685643048
acetate-onutilizing mutants of neurospora crassa. i. mutant isolation, complementation studies, and linkage relationships.sixty mutants of neurospora crassa unable to grow on acetate as sole source of carbon, but able to utilize sucrose, were isolated. on the basis of complementation tests, they were divided into seven groups, each group representing a different gene. six of the genes have been mapped; no two are closely linked. these loci have been designated acu-1 to acu-7. mutations at four of these loci result in poor germination of ascospores.19685643047
structure of the cell wall of pythium debaryanum.the structure of hyphal walls of pythium debaryanum was investigated by electron microscopy of shadowed replicas and thin sections, before and after digestion by snail gut enzymes or by 1 n hcl at 100 c for 1 hr, and by x-ray diffraction. we found that the wall had two phases, one composed of microfibrils of unknown composition and a second consisting of an amorphous matrix, part of which stained like protein with potassium permanganate and part of which was removed by snail-gut enzymes. in the ...19684868354
laminarinase of neurospora crassa. i. enzyme activity associated with conidia & conidial wall. 19684234673
effect of nitrogen source of cobalt toxicity in neurospora crassa. 19685645743
a new gene which affects uptake of neutral and acidic amino acids in neurospora crassa. 19685645735
the regulation of nitrate reductase and catalase by amino acids in neurospora crassa. 19685640154
[proteins from neurospora crassa. 1. immunochemical analysis of the cytoplasmic proteins from neurospora crassa and various mutants]. 19684973222
[proteins from neurospora crassa. 3. agar gel and immunoelectrophoretic analysis of enzymes and isoenzymes in various neurospora crassa strains]. 19684973224
comparative regulation of isoenzymic 3-deoxy-d-arabino-heptulosonate 7-phosphate synthetases in microorganisms.the independent control of regulatory isoenzymes by different metabolites constitutes one well-known pattern of control in branched metabolic pathways. this pattern was previously found to be widely distributed in the aromatic amino acid pathway of microorganisms in the case of the first enzyme of the sequence, 3-deoxy-d-arabino-heptulosonate 7-phosphate (dahp) synthetase. the comparative stability of the isoenzymes as well as the effect of aromatic amino acids in the growth medium upon the leve ...19684867215
the pathways of thiamine biosynthesis. some factors controlling synthesis of the pyrimidine moiety by thiamine auxotrophs of neurospora crassa. 19684875319
feedback inhibition of glutamine synthetase of neurospora crassa by nicotinamide-adenine dinucleotide. 19684300703
mechanism of choline o-sulphate utilization in fungi.1. the position of the enzyme blocks in a number of parathiotrophic mutants of aspergillus nidulans a 69 and mutants a and c of a biotinless mutant of aspergillus nidulans were examined by nutritional and heterokaryosis experiments and by assay in vitro of enzyme systems and specific enzymes. 2. the mutants were in five groups: a and c blocked at sulphate transport; gamma at atp sulphurylase; iota at adenosine 5'-sulphatophosphate kinase; eta at the adenosine 3'-phosphate 5'-sulphatophosphate re ...19685637353
induced mutation in uv-sensitive mutants of aspergillus nidulans and neurospora crassa. 19685672966
an acetohydroxy acid synthetase from neurospora crassa. 19685677177
the metabolism of aromatic acids by micro-organisms. metabolic pathways in the fungi.1. the metabolic pathways of aromatic-ring fission were examined in a range of fungal genera that utilize several compounds related to lignin. 2. most of the genera, after growth on p-hydroxybenzoate, protocatechuate or compounds that are degraded to the latter (e.g. caffeate, ferulate or vanillate), rapidly oxidized these compounds, but not catechol. 3. such genera possessed a protocatechuate 3,4-oxygenase and accumulated beta-carboxymuconate as the product of protocatechuate oxidation. this en ...19685691754
the metabolism of aromatic acids by micro-organisms. a reassessment of the role of o-benzoquinone as a product of protocatechuate metabolism by fungi.1. the addition of aniline to cultures of several yeasts, fusarium oxysporum and neurospora crassa growing with protocatechuate as sole carbon source resulted in the precipitation of dianilino-o-benzoquinone (anil). this product was also formed, however, if the medium was uninoculated. 2. the physical presence of yeast cells (living or dead) increased the anil yields in debaryomyces subglobosus cultures. 3. no anil was formed if p-hydroxybenzoate was the growth substrate. 4. o-benzoquinone was a ...19685691755
Displaying items 501 - 600 of 5889