Publications

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effects of suppressor mutations on nonalleic glucose 6-phosphate dehydrogenase mutants of neurospora crassa. 19734270987
the neutral carotenoids of wild-type and mutant strains of neurospora crassa. 19734270986
correlation of growth inhibition patterns to nucleoside transport models in neurospora crassa.growth of inhibition patterns provide evidence for a common nucleoside transport or utilization system, a separate system or systems for adenine transport, and another adaptable mechanism of adenosine transport.19734270445
effects of glycine and serine on serine hydroxymethyltransferase levels in logarithmic cultures of neurospora crassa wild type and ser-1-mutant. 19734271349
the identification of a third b-galactosidase activity in neurospora crassa. 19734271074
products of mitochondrial protein synthesis in neurospora crassa. determination of equimolar amounts of three products in cytochrome oxidase on the basis of amino-acid analysis. 19734359388
genetic characterization of ad-3 mutants induced by chemical carcinogens, i-phenyl-3-monomethyltriazene and i-phenyl-3,3-dimethyltriazene, in neurospora crassa. 19734271461
cellular compartmentation of aromatic amino acids in neurospora crassa. ii. synthesis and misplaced accumulation of phenylalanine in phen-2 auxotrophs. 19734270797
sex-hormones in neurospora crassa: further studies on its biological properties. 19734270872
partial characterization of transfer rna genes isolated from neurospora crassa. 19734273106
separation of the neutral carotenoids of neurospora crassa using concave gradient elution chromatography. 19734270371
repressible extracellular nucleases in neurospora crassa. 19734270540
mitochondrial protein synthesis and cyanide-resistant respiration in copper-depleted, cytochrome oxidase-deficient neurospora crassa. 19734356494
mutations in neurospora crassa affecting ascus and ascospore development. 20134273813
regulation of phosphate metabolism in neurospora crassa. characterization of regulatory mutants.a mutant of neurospora crassa, called uw-6, differs from wild type in being partially constitutive for synthesis of a species of alkaline phosphatase, and also for a species of phosphate permease that has a high affinity for phosphate at high ph. uw-6 is possibly allelic with a mutant called nuc-2 that was previously isolated by ishikawa. nuc-2 has the converse phenotype, in that it cannot be derepressed for either of these two activities. uw-6 is co-dominant with its wild-type allele in heterok ...19734271653
a search for complexity at the mating-type locus of neurospora crassa. 19734271649
influence of l-sorbose on the growth and morphology of neurospora crassa. 19734271185
the peptides of the hyphal wall of neurospora crassa. 19734271184
cellular compartmentation of aromatic amino acids in neurospora crassa. i. occupation of a protein synthesis pool by phenylalanine in tyr-1 mutants. 19734270570
mutation in neurospora crasa affecting some of the extracellular enzymes and several growth characteristics.a mutant of neurospora crassa, strain t9, which shows reduced activity of glucoamylase, was isolated. the mutant glucoamylase was not altered in ph optimum, or thermostability, but altered in elution profile of bio-gel filtration. the t9 mutation led to other distinct phenotypic effects: a poor growth response, resistance to the effect of sorbose, a high activity of extracellular acid phosphatase, and an increased sensitivity to high osmolarity of the growth medium. the discussion was based on t ...19734269585
cold-sensitive mutants of neurospora crassa.cold-sensitive mutants of the eucaryote neurospora crassa have been isolated by a modification of the filtration-enrichment technique of catcheside. the mutants include osmotic remedial, auxotrophic, transport, and incorporation deficient isolates.19734269583
inhibition of ribosomal rna synthesis during a shift-down transition of growth in neurospora crassa. 19734270631
[microbiological transformation of estrogens. transformation of equilenine into 12 beta-dihydroequilenine by neurospora crassa]. 19734276716
role of the redox state of nicotinamide adenine dinucleotides in the in vivo regulation of inositol biosynthesis in neurospora crassa. 19734147849
cyclic 3',5'-amp phosphodiesterase of neurospora crassa. 19734354445
complementation analysis of metabolite-resistant mutations with forced heterokaryons of neurospora crassa.the double mutant strain pyr-3 arg-12(s) is a prototroph because a common precursor of arginine and pyrimidine is supplied by the arginine pathway. growth of this strain is inhibited by exogenous citrulline or arginine. citrulline-resistant mutants of this strain were selected, and they resulted from modifier mutations at other loci. forced heterokaryons were used to study complementation among these modifiers. since the complementation test requires the scoring of non-growth as the positive res ...197317248629
biochemical basis of radiation-sensitivity in mutants of neurospora crassa. 19734270666
tryptophan metabolism and kynureninase induction in mutants of neurospora crassa resistant to 4-methyl-tryptophan.mutants of neurospora crassa that are resistant to 4-methyl-tryptophan were found to differ in ability to synthesize kynureninase in the presence of the inducers kynurenine, 3-oh-kynurenine, n-formyl-kynurenine, tryptophan, and indole. one strain (mtr26), although incapable of accumulating intracellular pools of these compounds, showed induced synthesis of kynureninase, whereas the second (mtr21) could neither accumulate nor be induced by them. strain mtr21, with the suppressor su(mtr), could no ...19734269379
characterization of excision repair in neurospora crassa.the excision of pyrimidine dimers from the deoxyribonucleic acid (dna) of neurospora crassa was examined. postirradiation incubation in the presence of several chemicals known to inhibit various repair systems indicated that caffeine reduced the rate of excision twofold, but did not inhibit excision completely as did proflavine and quinacrine. examination of the time course of excision showed that repair occurs at a relatively rapid rate: approximately 60 dimers excised per min after 500 ergs/mm ...19734269375
action of single-strand specific neurospora crassa endonuclease on ultraviolet light-irradiated native dna. 19734270183
properties of chorismate synthase in neurospora crassa. 19734146266
mitochondrial translation products before and after integration into the mitochondrial membrane in neurospora crassa. 19734270056
regeneration of invertase in neurospora crassa.in neurospora, invertase is predominately an extracellular enzyme, and acid phosphatase is partially external in location. both extracellular invertase and acid phosphatase were rapidly and quantitatively inactivated by acid treatment (ph 1.3). when such acid-treated cells were incubated with a suitable carbon source, a substantial regeneration of invertase activity occurred, but no restoration of acid phosphatase could be detected. the regeneration of invertase does not occur by renaturation of ...19734268689
structure and plugging of septa of wild type and spreading colonial mutants of neurospora crassa. 19734354924
electron microscopy of selectively stimulated microconidiogenesis in wild type neurospora crassa. 19734354923
lack of guanosine tetraphosphate accumulation during inhibition of rna synthesis in neurospora crassa. 19734269209
expression of the mitochondria genome in wild type and in extracellular mutants of neurospora crassa. 19734372151
alternative methods of preparation and analysis of quasicrystalline protein from neurospora crassa. 19734351946
different chromatographic forms of neurospora crassa nucleases specific for single-stranded nucleic acids. 19734268627
[studies on the conidial differentiation of "neurospora crassa". v. ultrastructure of the macroconidiogenous sequence (author's transl)]. 19734138206
the hyphal growth unit of wild type and spreading colonial mutants of neurospora crassa. 19734268673
growth of wild type and spreading colonial mutants of neurospora crassa in batch culture and on agar medium. 19734268672
circadian rhythms in neurospora: spatial differences in pyridine nucleotide levels.a growing colony of a mutant strain of neurospora crassa had two morphologically distinct areas which were formed as a result of a rhythmic spore-forming (conidiation) process. the total pyridine nucleotide content of these two areas was the same, but the levels of nadh, nadph, and nadp were lower in the conidiating area, while the nad level was higher. these biochemical differences in the adjacent areas of a single colony were only found in newly formed areas, and were not a permanent record. i ...19734144759
[selective conidiogenic effect of thymine on a "serineless" mutant of neurospora crassa]. 19734269682
virus-like particles in an estranuclear mutant of neurospora crassa.a particulate fraction not present in wild-type cells has been isolated from the cytoplasm and from lysed mitochondria of the respiratory-deficient extranuclear mutant "abnormal-1" of neurospora crassa. the particles have a density between 1.13 and 1.2 g/ml. they appear in thin sections after oso(4) fixation as virus-like polymorphic vesicles containing an electron-dense nucleoid of 120-170 nm in diameter. the central core is surrounded by one or two "unit membrane" envelopes of 100 a thickness. ...19734268098
adenine nucleotide levels in neurospora, as influenced by conditions of growth and by metabolic inhibitors.by a combination of luciferase and fluorescence methods adenine nucleotide pools in neurospora crassa have been examined under various conditions of growth and metabolic inhibition. during sustained exponential growth (25 c, shaking liquid cultures), the intracellular adenosine 5'-triphosphate (atp) concentration, [atp](i), rises slowly from the conidial level near 1 mm (1 mmol/kg of cell water) to a maximum of 2.0 to 2.5 mm at 14 h, after which it slowly declines. the adenosine 5'-diphosphate a ...19734267534
transport of c 4 -dicarboxylic acids in neurospora crassa. 19734268075
circular dichroism of a membrane protein of neurospora crassa. 19734703556
selection of respiratory mutants of neurospora crassa.a method is described that permits the isolation of mutants that are defective in mitochondrial respiration. the techniques of inositol-less death and overlay with 2,3,5-triphenyl-2h-tetrazolium chloride are utilized to select for mutant colonies. colonies that survive inositol-less death and fail to reduce the tetrazolium dye are then tested polarographically for cyanide-sensitive respiration. a preliminary characterization of three mutants obtained by this method is presented. the mutants have ...19734349028
genetic analysis of purple adenine (ad-3) mutants induced by methyl methanesulfonate in neurospora crassa. 19734348927
changes in enzyme activity of germinating conidia of neurospora crassa. 19734274506
interrelationships in trace-element metabolism in metal toxicities in a cobalt-resistant strain of neurospora crassa.a strain of neurospora crassa was isolated by training the mould to grow on media containing high concentrations of co(2+). this strain, the co(r) strain, exhibited approximately tenfold the resistance of the parent strain to co(2+) and ni(2+) but not to zn(2+) or cu(2+). co(2+) toxicity in the co(r) strain was reversed by mg(2+) but not by fe(3+). also, co(2+) did not affect iron metabolism in this strain. it is suggested that the mechanism of resistance in the co(r) strain involves an alterati ...19734269100
action of rec-3 on recombination near the amination-1 locus of neurospora crassa. 19734268716
role of lysine and -n-trimethyllysine in carnitine biosynthesis. i. studies in neurospora crassa. 19734266139
the inhibition of the neurospora crassa nitrate reductase complex by metal-binding agents. 19734144237
enzymatic hydrolysis of penicillin g and other phenylacetylamino compounds by neurospora crassa acylase. 19734693635
branded chain amino acid aminotransferases of neurospora crassa. 19734268214
histidine uptake in mutant strains of neurospora crassa via the general transport system for amino acids.a transport double mutant of neurospora crassa has been isolated that has only one of the three transport systems capable of l-histidine uptake. the substrate specificity of the remaining transport system, termed the general transport system, has been fully characterized with regard to the contributions to binding of the side chain, the alpha-amino group, and the carboxylate group. the positively charged alpha-amino group is necessary for binding; the negatively charged carboxylate group is of l ...19734266243
regulation of glycogen phosphorylase a phosphatase in neurospora crassa. 19734350266
the isolation of the components of the anthranilate synthetase complex from neurospora crassa. 19734265643
aldosugar dehydrogenases from neurospora crassa partial purification and characterization of d-arabinose: nad dehydrogenase. 197311947073
insulin inhibition of membrane-bound adenylate cyclase in neurospora crassa. 197311947065
comparison of the respiratory chain of neurospora crassa wild type and the mi-mutants mi-1 and mi-3. 19734144164
ribosomal rna synthesis in mitochondria of neurospora crassa. 19734268438
growth regulation in neurospora crassa. effects of nutrients and of temperature. 19734268110
sterol mutants of neurospora crassa: their isolation, growth characteristics and resistance to polyene antibiotics. 19734265660
differential gene action in neurospora crassa.molecular hybridization experiments with pulse-labeled total ribonucleic acid (rna) or isolated nonribosomal rapidly labeled rna species and deoxyribonucleic acid from growth periods of 8, 16, and 24 hr of neurospora crassa showed differential transcription. hybridization competition experiments between rna species isolated from 8, 16, and 24 hr of growth showed qualitative differences in the types of rna synthesized during these periods.19734266171
life cycle of neurospora crassa viewed by scanning electron microscopy.scanning electron microscopy was used to examine the major stages of the life cycle of two wild-type strains of neurospora crassa shear and dodge (st. lawrence 3.1a and 74a): mycelia, protoperithecium formation, perithecia, ascospores, ascospore germination and outgrowth, macro and microconidia, and germination and outgrowth of macroconidia. structures seen at the limit of resolution of bright-field and phase-contrast microscopes, e.g., the ribbed surface of ascospores, are well resolved. new de ...19734266170
the manipulation of mutation-induction kinetics in neurospora crassa. 19734726377
the relationship between atp and an electrogenic pump in the plasma membrane of neurospora crassa. 19734360924
enzymatic properties of a repressible acid phosphatase in neurospora crassa. 19734350735
[metabolic products of microorganisms. 120. uptake of iron by neurospora crassa. ii. regulation of the biosynthesis of sideramines and inhibition of iron transport by metal analogues of coprogen (author's transl)]. 19734272844
morphological mutants of neurospora crassa: possible evidence of abnormal morphology due to changes in dna composition. 19734272373
apparent effect of pentachloronitrobenzene on the hyphal wall polysaccharides of two strains of neurospora crassa. 19734272173
[studies on the conidial differentiation of "neurospora crassa". iv. chemo-structural modifications of the wall in the wild type and two aconidial mutants]. 19734269228
aryl sulfatase in ascospores of neurospora crassa.neurospora crassa ascospores normally do not contain aryl sulfatase even when formed under conditions of sulfur limitation. however, when one of the parental strains is the nonrepressible mutant scon(c), the resulting (mixed) ascospores contain significant levels of aryl sulfatase even when formed under conditions of sulfur abundance.19734265939
alkaline phosphatases of neurospora crassa. 3. effects of ph and mechanism of action. 19734265429
[metabolic products of microorganisms. 115. uptake of iron by neurospora crassa. i. to the specificity of iron transport]. 19734265135
formation and reduction of intermediate acyladenylate by aryl-aldehyde. nadp oxidoreductase from neurospora crassa. 19724405494
induction of mitochondrial rna polymerase in neurospora crassa. 19724264635
adenylate cyclase activity in lubrol-treated membranes from neurospora crassa. 19724265406
[the isolation and characterization of a nadh: semidehydroascorbic acid oxidoreductase from neurospora crassa]. 19724405497
ubiquinone function in neurospora crassa.mitochondria of cytoplasmic respiratory mutants [mi-1] (poky) and [mi-4] contain about a fourfold molar excess of ubiquinone as compared to the wild-type strain of neurospora crassa. in the wild type and [mi-1] cultures the concentration of ubiquinone remains constant during the exponential and stationary phase of growth. in [mi-4] cultures it markedly decreases in the stationary phase. the reduction of ubiquinone by substrates is approximately the same in the three strains tested and amounts 60 ...19724344917
identification of sexual hormones in neurospora crassa. 19724267851
genetic and metabolic control of sulfate metabolism in neurospora crassa: a specific permease for choline-o-sulfate. 19724265021
the kinetics of l-aspartate transport in neurospora crassa conidia. 19724264473
adenylate cyclase activity in neurospora crassa. i. general properties. 19724343160
purification and stability of the multienzyme complex encoded in the arom gene cluster of neurospora crassa. 19724263953
adenylate cyclase activity in neurospora crassa. ii. kinetics. 19724263616
different pool sizes of the precursor polypeptides of cytochrome oxidase from neurospora crassa. 19724344829
regulation of inositol biosynthesis in vivo by pyrophosphate in neurospora crassa. 19724344827
inhibition of the assembly of cytochrome oxidase in neurospora crassa by chloramphenicol. 19724344826
cytochrome b in neurospora crassa mitochondria. a membrane protein containing subunits of cytoplasmic and mitochondrial origin. 19724264399
effect of pyrrolnitrin on electron transport and oxidative phosphorylation in mitochondria isolated from neurospora crassa.pyrrolnitrin, at low concentrations, uncouples oxidative phosphorylation in neurospora mitochondria. at higher concentrations, pyrrolnitrin inhibits electron transport both in the flavine region and through cytochrome oxidase.19724343822
tryptophan transport in neurospora crassa by various types of mtr revertants. 19724265907
control of acetohydroxy acid synthetase in neurospora crassa. 19724265245
direct induction in wild-type neurospora crassa of mutants (qa-1 c ) constitutive for the catabolism of quinate and shikimate.a color test has been developed for the selection and identification of mutants in neurospora crassa, constitutive for the three normally inducible enzymes which convert quinate to protocatechuate. by this means seven such mutants have been recovered after ultra violet irradiation of wild type and have been shown to be allelic (or very closely linked) to the qa-1(c) mutants previously obtained by other means. thus, the regulation of the synthesis of these three catabolic enzymes is indicated to ...19724264707
ribosomal rna genes of neurospora: isolation and characterization.dna sequences in neurospora crassa that code for ribosomal rna have been isolated in a highly purified state by dna-rna hybridization. about 100 separate ribosomal rna genes exist in each nucleus. these genes are composed of repeated sequences that are present about 100 times per nucleus. the individual members of this group of dna sequences are essentially identical.19724264050
regulation of pyridine nucleotide levels and ratios in neurospora crassa. 19724405599
thymidine 2'-hydroxylation in neurospora crassa. 19724265566
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