Publications

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the nature of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in extracts of wild-type neurospora crassa: a reaction controlled by two activating substrates and three allosteric negative modifiers. 19684968658
genetic and complementation studies of a new carotenoid mutant of neurospora crassa. 19685699832
heterokaryotic transmission of factors affecting recombination in neurospora crassa. 19685699828
role of iron in the regulation of heme biosynthesis in neurospora crassa. 19685653647
homocitrate formation in neurospora crassa. relation to lysine biosynthesis. 19684296471
amino acid incorporation by cell-free extracts of neurospora crassa. 19685649916
chromatographic differences between the cytoplasmic and mitochondrial trnas of neurospora crassa. 19685656076
observations on the tube method of measuring growth rate in neurospora crassa. 19685652094
growth of neurospora crassa in unstirred liquid cultures. 19685652093
genetic control of aspartate transcarbamylase by the pyr-3 locus of neurospora crassa. 19685649514
a membranelike fraction from neurospora crassa, i. structure of "membranes" and release of free amino acids. 19685240019
enzyme activities during the asexual cycle of neurospora crassa. ii. nad- and nadp-dependent glutamic dehydrogenases and nicotinamide adenine dinucleotidase.three enzymes, (a) nicotinamide adenine diphosphate-dependent glutamic dehydrogenase (nad enzyme), (b) nictoinamide adenine triphosphate-dependent glutamic dehydrogenase (nadp enzyme), and (c) nicotinamide-adenine dinucleotidase (nadase), were measured in separate extracts of neurospora crassa grown in vogel's medium n and medium n + glutamate. specific activities and total units per culture of each enzyme were determined at nine separate intervals phased throughout the asexual cycle. the separa ...19684384627
control of nitrate reductase by iron in neurospora crassa. 19685661623
evidence for two types of 18-s ribosomal rna in neurospora crassa. 19685642641
[light-dependent carotenoid synthesis : iv. the role of oxygen in photoinduction].the purpose of these studies was to investigate wether the primary step in the reaction chain of the light-dependent carotenoid synthesis in heterotrophic organisms, the photochemical reaction of the photoreceptor, requires oxygen. submerged cultures of fusarium aquaeductuum and neurospora crassa were used.biosynthesis of carotenoids following a photoinduction occurred only under aerobic conditions. when the mycelia were illuminated in the absence of oxygen and subsequently transferred to aerobi ...196824515321
phenylalanine-tyrosine biosynthesis in neurospora crassa. 196817248403
somatic cell variation during uninterrupted growth of neurospora crassa in continuous growth tubes. 19685652069
tryptophan transport in neurospora crassa. ii. metabolic control.the rate of tryptophan transport in neurospora is regulated by the intracellular pool of tryptophan. when cells were shifted from growth in minimal medium to tryptophan-containing medium for 10 min, there was a 50% reduction in the rate of tryptophan transport. intracellular tryptophan pools derived from indole were equally effective in reducing the rate of transport as externally supplied tryptophan. the regulatory influence of tryptophan on the transport system appears to be a property of all ...19685643067
nature of the complementation products formed by a complementing mutant of neurospora crassa.the mutant am-14 produces no active nicotinamide adenine dinucleotide phosphate-linked glutamate dehydrogenase (gdh) and no protein showing immunological cross-reaction with the enzyme. nevertheless, it shows complementation with several other am mutants in heterokaryons. active gdh can be extracted from heterokaryons formed from am-14 and other mutants which, by themselves, produce more or less inactive varieties of the enzyme. the enzyme from am-14 + am-3 heterokaryons can be partially separat ...19685643060
acetate-nonutilizing mutants of neurospora rassa. ii. biochemical deficiencies and the roles of certain enzymes.the levels of krebs cycle, glyoxylate cycle, and certain other enzymes were measured in a wild-type strain and in seven groups of acetate-nonutilizing (acu) mutants of neurospora crassa, both after growth on a medium containing sucrose and after a subsequent 6-hr incubation in a similar medium, containing acetate as the sole source of carbon. in the wild strain, incubation in acetate medium caused a rise in the levels of isocitrate lyase, malate synthase, phosphoenolpyruvate carboxykinase, acety ...19685643048
acetate-onutilizing mutants of neurospora crassa. i. mutant isolation, complementation studies, and linkage relationships.sixty mutants of neurospora crassa unable to grow on acetate as sole source of carbon, but able to utilize sucrose, were isolated. on the basis of complementation tests, they were divided into seven groups, each group representing a different gene. six of the genes have been mapped; no two are closely linked. these loci have been designated acu-1 to acu-7. mutations at four of these loci result in poor germination of ascospores.19685643047
structure of the cell wall of pythium debaryanum.the structure of hyphal walls of pythium debaryanum was investigated by electron microscopy of shadowed replicas and thin sections, before and after digestion by snail gut enzymes or by 1 n hcl at 100 c for 1 hr, and by x-ray diffraction. we found that the wall had two phases, one composed of microfibrils of unknown composition and a second consisting of an amorphous matrix, part of which stained like protein with potassium permanganate and part of which was removed by snail-gut enzymes. in the ...19684868354
laminarinase of neurospora crassa. i. enzyme activity associated with conidia & conidial wall. 19684234673
effect of nitrogen source of cobalt toxicity in neurospora crassa. 19685645743
a new gene which affects uptake of neutral and acidic amino acids in neurospora crassa. 19685645735
the regulation of nitrate reductase and catalase by amino acids in neurospora crassa. 19685640154
evidence for nonsense mutations in the arom gene cluster of neurospora crassa. 19685710960
c-terminal analysis of histidinol dehydrogenase from neurospora crassa. 19685679374
[mechanism of action of thiopicolinic acid anilide in neurospora crassa]. 19684237100
growth of a neurospora crassa lysine auxotroph on glutaric acid. 19685666732
the pathways of thiamine biosynthesis. separation, purification, and identification of some precursors of the pyrimidine moiety of thiamine produced by neurospora crassa auxotrophs. 19685666944
utilization of exogenous and endogenous ornithine by neurospora crassa.through the use of a mutant deficient in ornithine-delta-transaminase (ota), it is shown that this enzyme normally has no obligate or even major biosynthetic role in neurospora. the pathways of ornithine and proline synthesis proceed wholly independently of each other in ota-less strains. it is probable that ota functions as an enzyme of arginine catabolism. with mutants affected in ota, ornithine transcarbamylase, and the synthesis of ornithine, it was demonstrated that exogenous and endogenous ...19685674053
mutants of neurospora crassa deficient in ornithine-delta-transmainase.the arg-12(s) mutation of neurospora causes a partial block in the ornithine transcarbamylase (otc) reaction. strains carrying this mutation will use endogenous ornithine, but not exogenous ornithine, as a precursor of arginine. certain strains carrying arg-12(s) may be used for direct selection of variants able to use exogenous ornithine as an arginine precursor. among eight such derivatives, six lacked the catabolic enzyme ornithine transaminase (ota). all six mutations were alleles of a singl ...19685674052
regulation of "malic" isozymes and malic dehydrogenases in neurospora crassa. 19685667339
[endoplasmic reticulum and centripetal progression of the interconidial septum in a morphologic mutant of neurospora crassa]. 19685705255
the relationship of ethanol dehydrogenase to morphogenesis of neurospora crassa. 19685727908
analysis of a case of mutagen specificity in neurospora crassa. i. dose-response curves. 19685713537
biosynthesis of betaine in neurospora crassa. 19685711186
[metabolic control and ultrastructural aspects of the conidiation (macro-microcondia) in neurospora crassa]. 19685699314
kinetic studies of mutation induction by epoxides in neurospora crassa. 19685683008
a mutagenic after-effect associated with ethylene oxide in neurospora crassa. 19685683006
homology tests on presumed multilocus deletions in the ad-3 region of neurospora crassa induced by the acridine mustard icr-170. 19685656345
genetic analysis of the extent and type of functional inactivation in irreparable recessive lethal mutations in the ad-3 region of neurospora crassa. 19685656344
non-nuclear inheritance of uv sensitivity in neurospora crassa. 19685759970
the effect of cycloheximide on carotenoid biosynthesis in neurospora crassa. 19685704312
anthranilic acid as a feedback inhibitor of glutamine synthetase of neurospora crassa. 19685704311
the in vivo iron donor for haem synthesis in neurospora crassa. 19684239950
the formation of 5-formyluracil by cell-free preparations from neurospora crassa. 19684387266
induced macroconidia formation in neurospora crassa. 19685721155
[inclusion of adenine-8-c14 into the ribosomes and polyribosomes of germinating conidia and mycelium of a neurospora crassa 28610 ad. strain deficient in adenine]. 19685747531
in vivo regulation of intermediate reactions in the pathway of tryptophan biosynthesis in neurospora crassa.the in vivo regulation of intermediate reactions in the pathway of tryptophan synthesis in neurospora crassa was examined in a double mutant (tr-2, tr-3) which lacks the functions of the first and last enzymes in the pathway from chorismic acid to tryptophan. the double mutant can convert anthranilic acid to indole and indole-3-glycerol, and the production of these indolyl compounds by germinated conidia was used to estimate the activity of the intermediate enzymes in the pathway. indole-synthes ...19685726311
the exogenous environment as a factor in the control of the 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase of neurospora crassa. 19685729957
a new locus in the tryptophan pathway of neurospora crassa. 19685708292
specific inhibition by atp and other properites of an endonuclease of neurospora crassa. 19685701229
electrophoretic pattern of and amino acid incorporation in vitro into the insoluble mitochondrial protein of neurospora crassa wild type and mi-1 mutant. 196811945305
alteration of tryptophan-mediated regulation in neurospora crassa by indoleglycerol phosphate.the accumulation of imidazoleglycerol phosphate during growth of neurospora crassa in the presence of 3-amino-1,2,4-triazole was found to cause derepression of tryptophan synthetase and to inhibit the induction of kynureninase. accumulation of indoleglycerol phosphate in response to growth in the presence of indole acrylic acid or anthranilic acid was also accompanied by derepressed synthesis of tryptophan synthetase. enzyme synthesis in mutants (his-7 and trp-4) unable to form these intermediat ...19685650070
regulation of enzyme synthesis in neurospora crassa. bnwl-714. 19685307103
catabolite repression of malic dehydrogenase in neurospora crassa. 19676054686
enzyme activities during the asexual cycle of neurospora crassa. i. succinic dehydrogenase. 19676054680
the preparation and biochemical properties of mitochondria from neurospora crassa. 19676052632
deacetylation of n-acetyl-l-glutamic acid by neurospora crassa. 19676035272
genetic control of allelic recombination at the histidine-3 locus of neurospora crassa. 19676082625
synchronous mitochondrial division in neurospora crassa.samples of mycelium of neurospora crassa of known age were harvested from agar plates and examined with the electron microscope. the relative volume of the mitochondria was determined for mycelium of different ages. the volume measurements indicated that the mitochondria were dividing synchronously in fronts 6, 13, and 22(1/2) hr behind the growing hyphal tips. the sequence of mitochondrial division is hypothesized to include mitochondrial cupping followed by division which results in closely as ...19676064362
isolation of mutant strains of neurospora crassa from differentially surviving ascospores. 19675588793
a new white ascospore mutant of neurospora crassa. 19674968445
[on phosphorous compounds in preparations of cell walls from neurospora crassa mycelia]. 19675597389
the effects of light on a circadian rhythm of conidiation in neurospora.the expression of a circadian rhythm of conidiation by timex, a strain of neurospora crassa, is inhibited by growth in continuous white light. the action spectrum for this effect has a strong peak (with minor subpeaks) in the blue region of the visible spectrum, and a broad shoulder in the near ultraviolet. this action spectrum suggests that a carotenoid or flavin compound may be the photoreceptor, but does not allow one to determine conclusively whether the receptor is indeed a carotenoid, flav ...196716656687
photoreactivating enzyme from neurospora crassa. 19676077698
altered aspartate transcarbamylase of neurospora crassa responsible for a suppressor effect. 19676066249
ultrastructural studies of microconidium formation in neurospora crassa.microconidiating cultures of "peach-fluffy" (pe, fl; y8743m, l; fgsc #569) were fixed at various times after the initiation of growth and examined with an electron microscope. hyphae from which microconidia form are markedly vacuolated and show a much more extensive system of rough endoplasmic reticulum than young vegetative hyphae. a bulge in the hypha presages the start of microconidium formation, followed by the rupture of the outermost wall layers. a thick collar forms around the protruding ...19676066052
multiple alterations in metabolite uptake in a mutant of neurospora crassa.a temperature-conditional lethal mutant of neurospora crassa, un-t (55701), was resistant to neutral amino acid analogues by virtue of a decreased ability to transport these analogues and their natural congeners across the cell membrane. the uptake of acidic, but not basic, amino acids was also impaired, as was the uptake of potassium ions. after preincubation above the tolerated temperature, the ability to take up a still wider variety of metabolites was greatly reduced. protoplasts of the muta ...19676057809
catabolism of l-arginine in neurospora crassa. 19675583768
a survey of new morphological mutants in neurospora crassa. 19675583730
the occurrence of two dehydroquinases in neurospora crassa, one constitutive and one inducible. 19674966264
linkage relations of new morphological mutants in linkage group v of neurospora crassa. 19674868675
the serine biosynthetic pathway in neurospora crassa. 19676077050
amino acid substitutions in mutant forms of histidinol dehydrogenase from neurospora crassa.amino acid changes in the enzyme l-histidinol dehydrogenase (l-histidinol-nad oxidoreductase, ec 1.1.1.23) have been determined between the wild-type neurospora crassa and two temperature-sensitive mutants. comparison was made between amino acid analyses of peptides of differing electrophoretic and chromatographic mobilities resulting from tryptic and chymotryptic digestion of protein from wild-type and mutant k26, and wild-type and mutant k445 strains, respectively. the analyses demonstrate the ...19676056636
the size distribution of x-ray induced multilocus deletions in the ad-3 region of neurospora crassa. 19675584575
"no-growth"-complementation in forced heterokaryons from sorbose-resistant (transport-defective) neurospora crassa mutants. 19674385815
involvement of a b-type cytochrome in the assimilatory nitrate reductase of neurospora crassa. 19674384346
3-deoxy-d-arabino-heptulosonic acid 7-phosphate synthetase as an "allosteric" function and ligand interactions with this enzyme from neurospora crassa. 19676064585
mitochondrial and cytoplasmic polysomes from neurospora crassa. 19676055444
properties of a phosphatidylmonomethylethanolamine n-methyl-transferase from neurospora crassa. 19676060457
argininosuccinate synthetase of neurospora crassa. 19676078087
actinomycin d-induced phenotypic reversion in neurospora crassa. 19676077527
phosphoglucomutase mutants and morphological changes in neurospora crassa. 19675233848
ribosomal rna and ribosomes from mitochondria of neurospora crassa. 19675233834
regulation of the "malic" enzyme in neurospora crassa. 19674383262
the accumulation of argininosuccinate in neurospora crassa. ii. inhibition of arginyl-trna synthesis by argininosuccinate. 19676053229
the accumulation of argininosuccinate in neurospora crassa. i. elevated ornithine carbamoyl transferase with high concentrations of arginine. 19676053228
ultraviolet-sensitive mutants in neurospora crassa. 19676061668
glutamic acid dehydrogenases in quiescent and germinating conidia of neurospora crassa. 19676038892
[purification of ribonucleases of neurospora crassa and their properties]. 19675626108
the catabolism of l-arginine by neurospora crassa. 19676048315
studies of a homoserineless bradytroph of neurospora crassa: demonstration of an altered aspartate beta-semialdehyde dehydrogenase. 19674383000
genetic control of the structure and activity of an enzyme aggregate in the tryptophan pathway of neurospora crassa. 19676052569
the effect of oxygen tension on growth, conidiation, and alcohol production of neurospora crassa. 19676036884
studies on malate dehydrogenases and aspartate aminotransferases from neurospora crassa. 19676035063
structure and composition of the cell wall of neurospora crassa.the structure and composition of the cell walls of hyphae of neurospora crassa were investigated by electron microscopy, chemical analysis, and x-ray diffraction both before and after progressive enzymatic degradation by snail gut enzymes, chitinase, and trypsin. the wall consists of two phases: randomly disposed skeletal microfibrils of chitin only and an amorphous matrix which contains both beta-glucans and protein. the protein contains a high percentage of the amides of aspartic and glutamic ...19676027990
lepid content of conidia of neurospora crassa. 19676060645
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