Publications

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an electron microscope and biochemical study of neurospora crassa during development. 196514328416
some carbon-dioxide requiring mutants of neurospora crassa. 196514328414
the effect of temperature on the production of perithecia by neurospora crassa. 196514328412
[intracellular localization of proteolytic enzymes of neurospora crassa. i. function and subcellular distribution of proteolytic enzymes]. 196514306495
an extended model of periodic linkage in neurospora crassa. 19655868860
a method for the automatic collection of ordered ascospores from neurospora crassa. 19655326032
the amino acid sequence of cytochrome c of neurospora crassa. 19655218916
a ribonucleic acid fraction of neurospora crassa evoking development of a pseudo-tryptophan synthetase activity by extracts of mutants td-1, td-2, and td-3. 19655867005
changes in enzymes regulating isocitrate breakdown in neurospora crassa. 19654379827
[intracellular localization of proteolytic enzymes of neurospora crassa. ii. identification of protease-containing cell structures]. 19654958292
relationship of the major constituents of the neurospora crassa cell wall to wild-type and colonial morphology.mahadevan, p. r. (the rockefeller institute, new york, n.y.), and e. l. tatum. relationship of the major constituents of the neurospora crassa cell wall to wild-type and colonial morphology. j. bacteriol. 90:1073-1081. 1965.-the relationship of cell wall to morphology in neurospora crassa was studied by correlating the levels of structural polymers of the cell wall with wild-type and colonial morphology. the cell wall of n. crassa contains at least four major complexes: a peptide-polysaccharide ...19655847797
the enzymatic conversion of anthranilate to indolylglycerol phosphate in neurospora crassa. 19655842052
a cytoplasmic character in neurospora crassa. the role of nuclei and mitochondria.nuclear fractions isolated from mutants of neurospora produced no effect when microinjected into mutants with complementary biochemical requirements. dna isolated from the nuclear fractions similarly injected also had no effect. mitochondrial fractions isolated from an abnormal inositolless strain (abn-1) produced drastic changes in the rate of growth, morphology, reproductive characteristics, and cytochrome spectra of normal inositolless strains when single hyphal compartments were microinjecte ...19655865933
regulation of cellulase and cellobiase in neurospora crassa. 19665970513
a study of conidiation in neurospora crassa. 19665971388
[the dependence of p32 incorporation into mycelia of adenine deficient mutant of neurospora crassa on the concentration of adenine in the medium and on the presence of 8-azaadenine]. 19665995918
a cytoplasmic variant of neurospora crassa. 19665968641
genetic controls of recombination i. the recombination-2 gene of neurospora crassa. 19665230008
neurospora crassa cytochrome c. ii. chymotryptic peptides, tryptic peptides, cyanogen bromide peptides, and the complete amino acid sequence. 19665950080
neurospora crassa cytochrome c. i. purification, physical properties, amino acid composition, and peptide maps from "wild type" and "poky" strains. 19665912112
the utilization of leaky ad-3 mutants of neurospora crassa in heterokaryon tests for allelic complementation. 19665918504
amino acid production by amitochondrial fraction of neurospora crassa. 19665220957
inositol deficiency resulting in death: an explanation of its occurrence in neurospora crassa.the incorporation of radio-active inositol and choline into the cytoplasmzic membranes of inositol-and choline-auxotrophic mnutants of neuros-pora crassa revealed that the membrane of particles which contain proteases is relatively poor in lecithin and rich in inositol-phospholipid. in mycelia of the mutant requiring inositol, grown in a suboptimum amount of exogenous inositol, the strlctural initegrity of the protease particles is lost, and the bulk of intracellular protease activity is recover ...19665908969
protoperithecia in neurospora crassa: technique for studying their development.a technique is described which facilitates analysis of the development of individual protoperithecia in neurospora crassa. the formation of this organelle proceeds in several clearly discernible steps beginning with the looping of a single hyphal filament and ending with a heavily pigmented, densely packed structure that is the mature protoperithecial structure. the effects of a number of environmental conditions on the development of protoperithecia in two wild types and in a female-sterile mut ...19664410944
conidiation of neurospora crassa. 196621090502
regulation of enzyme synthesis in neurospora crassa. bnwl-480. 19665301008
carbon dioxide stimulation of the ad-3 mutants of neurospora crassa. 19665972694
genetic alteration of pore size and other properties of the neurospora cell wall.trevithick, john r. (university of wisconsin medical school, madison), robert l. metzenberg and donald f. costello. genetic alteration of pore size and other properties of the neurospora cell wall. j. bacteriol. 92:1016-1020. 1966.-several properties of the cell walls of wild type and the osmotic mutant of neurospora crassa have been examined. the peameability of the isolated cell walls to polyethylene glycol and dextran polymers of different molecular weights was investigated by the volume of d ...19665926738
the primary biochemical effect of a morphological mutation in neurospora crassa. 19664381935
immunoelectrophoretic analysis of cytoplasmic proteins of neurospora crassa. 19665965359
internuclear effects on prototroph frequencies of some crosses in neurospora crassa. 19665961489
an endonuclease from mitochondria of neurospora crassa. 19664287861
the dihydroxy acid dehydratase of neurospora crassa. 19665946629
on the in vitro development of pseudo-tryptophan synthase activity by extracts of neurospora crassa mutant strains td6 and td120. 19665961662
hybridization in vitro between wild-type and mutant forms of glutamate dehydrogenase from neurospora crassa. 19665947152
immunochemical and enzymatic studies and glutamate dehydrogenase and a related mutant protein from neurospora crassa.roberts, d. b. (university of cambridge, cambridge, england). immunochemical and enzymatic studies on glutamate dehydrogenase and a related mutant protein from neurospora crassa. j. bacteriol. 91:1888-1895. 1966.-when an investigation was made of the inhibition of neurospora glutamate dehydrogenase by bivalent and univalent antibodies, it was shown that the enzyme inhibition is not complete even with excess antibodies. the residual activity was some three times greater with bivalent antibodies, ...19665937244
interrelationships of sulfur amino acids in the pool and cellular protein of neurospora crassa. 19665961305
a repressible alkaline phosphatase in neurospora crassa. 19665946607
on the nature of folate derivatives of neurospora crassa and the effect of sulphanilamide. 19665989524
the dna content of centrioles of neurospora crassa during divisions i and iv of ascosporogenesis. 19665959217
a new incompatibility locus in neurospora crassa. 19665919333
genetic control of amino acid permeability in neurospora crassa.lester, gabriel (reed college, portland, ore.). genetic control of amino acid permeability in neurospora crassa. j. bacteriol. 91:677-684. 1966.-strains of neurospora crassa resistant to 4-methyltryptophan (4-mt) were isolated from populations of conidia exposed to ultraviolet light. in genetic crosses, 4-mt resistance behaved as a single-gene difference. resistance to 4-mt could not be attributed to a relaxation of control of the formation or the activity of the enzymes of tryptophan biosynthes ...19665883112
growth responses of neurospora crassa to increased partial pressures of the noble gases and nitrogen.buchheit, r. g. (union carbide corp., tonawanda, n.y.), h. r. schreiner, and g. f. doebbler. growth responses of neurospora crassa to increased partial pressures of the noble gases and nitrogen. j. bacteriol. 91:622-627. 1966.-growth rate of the fungus neurospora crassa depends in part on the nature of metabolically "inert gas" present in its environment. at high partial pressures, the noble gas elements (helium, neon, argon, krypton, and xenon) inhibit growth in the order: xe > kr> ar > ne > he ...19665883104
evidence of a microsomal factor required for in vitro development of pseudo-triptophan synthase activity by extracts of neurospora crassa. 19665941363
cobalt toxicity and iron metabolism in neurospora crassa.1. increasing concentrations of cobalt in the medium result in increased production of an iron-binding compound and a corresponding fall in catalase activity of neurospora crassa. 2. cobalt rapidly depletes the medium of iron by enhancing the rate of iron uptake by the mycelium. 3. with toxic amounts of cobalt there is a fall in bound (59)fe and haem (59)fe as well as a decreased incorporation of [2-(14)c]glycine into the mycelial haem fraction. the production of the iron-binding compound preced ...19665938658
amino acid transport in neurospora crassa. bnwl-280. 19665301139
tryptophan transport in neurospora crassa. i. specificity and kinetics.wiley, w. r. (battelle memorial institute, richland, wash.), and w. h. matchett. tryptophan transport in neurospora crassa. i. specificity and kinetics. j. bacteriol. 92:1698-1705. 1966.-the transport of tryptophan in neurospora crassa is mediated by a distinct stereospecific system which is chemically specific for a family of neutral amino acids. the process shows typical saturation kinetics and a sharp decrease in the rate of tryptophan uptake at low temperatures. the q(10) for the process is ...19665958105
purification and properties of ribonuclease n1, an extracellular ribonuclease of neurospora crassa. 19665972365
circadian nature of a rhythm expressed by an invertaseless strain of neurospora crassa.a new strain of neurospora crassa which exhibits a rhythm of conidiation when growing along an agar surface in a growth tube is described. the rhythm has been shown to be circadian for it meets the following criteria: a) the period under constant environmental conditions in the dark is about 24 hours (22.7 hours at 25 degrees ); b) the period is relatively temperature-independent (q(10) is between 0.95 and 1.21 for temperature range of 18 to 35 degrees ); c) the rhythm persists in continuous dar ...19665978549
susceptibility and resistance of several fungi to microbial lysis.potgieter, h. j. (cornell university, ithaca, n.y.), and m. alexander. susceptibility and resistance of several fungi to microbial lysis. j. bacteriol. 91:1526-1532. 1966.-strains of streptomyces, nocardia, and pseudomonas capable of lysing hyphae of fusarium solani or neurospora crassa were obtained by selective culture, but attempts to isolate an organism lysing rhizoctonia solani failed. when provided with f. solani or n. crassa as carbon sources, the actinomycetes tested produced beta-(1 --> ...19665929777
nonessentiality of boron in fungi and the nature of its toxicity.an investigation was undertaken to determine whether any of the following fungi had a requirement for boron (b): saccharomyces cerevisiae, aspergillus niger, neurospora crassa, and penicillium chrysogenum. boron was unessential, and hence a study was made of the concentrations of b that reduced the growth of s. cerevisiae and p. chrysogenum and the mode of action of the b toxicity. fifty and 4000 mg b/liter, respectively, significantly (5% level) reduced the growth of the latter 2 species.in bot ...196616656256
acyl derivatives of homoserine as substrates for homocysteine synthesis in neurospora crassa, yeast, and escherichia coli. 196712325384
regulation of glutamine synthetase. ii. patterns of feedback inhibition in microorganisms.the feedback inhibition of glutamine synthetase was investigated by use of partially purified enzyme preparations from salmonella typhimurium, micrococcus sodonensis, pseudomonas fluorescens, bacillus cereus, bacillus licheniformis, clostridium pasteurianum, rhodospirillum rubrum, neurospora crassa, candida utilis, and chlorella pyrenoidosa. inhibition analyses indicated that the enzyme of each organism can be effectively regulated with mixtures of end products from the diverse pathways of gluta ...19676025412
thiamine-dependent accumulation of tetramethylpyrazine accompanying a mutation in the isoleucine-valine pathway.a mutant of corynebacterium glutamicum was found to accumulate high concentrations of a material which crystallized upon cooling of the broth. the compound was identified as tetramethylpyrazine. the mutant was found to require isoleucine, valine, leucine, and pantothenate for growth. all four requirements probably result from the loss of a single enzyme of the isoleucine-valine pathway. since similar mutants of neurospora crassa accumulate acetoin, the present mutant probably forms tetramethylpy ...19676039355
a repressible acid phosphatase in neurospora crassa. 19676040372
ribosomes and ribosomal protein from neurospora crassa. i. physical, chemical, and immunochemical properties.ribosomes from neurospora crassa, initially characterized by ultracentrifugal and immunochemical analyses, have been used to prepare ribosomal protein for physical, chemical, and immunochemical study. the acrylamide gel disc electrophoretic profiles of neurospora ribosomal protein exhibit a degree of heterogeneity comparable to what has been observed in other systems. only by chemical modification or by aggregation of the protein do alterations in the profile become apparent. disulfide-bond form ...19674962303
ribosomes and ribosomal proteins from neurospora crassa. ii. ribosomal proteins in different wild-type strains and during various stages of development. 19674965202
the nature of photoactivation in neurospora crassa. 19675336978
localization of structural polymers in the cell wall of neurospora crassa.the distribution and localization of structural polymers in the cell wall of neurospora crassa has been studied by selective removal and light and electron microscope examination. observations with the light microscope indicated that each polymer by itself can provide structural integrity to the cell wall. examination by electron microscopy showed that the cell wall consists of an outer layer of thick fibrils, identified chemically as a glucan-peptide-galactosamine complex, and an inner layer ma ...19676055990
the purification and properties of histidinol dehydrogenase from neurospora crassa.1. a procedure is described for the purification of l-histidinol dehydrogenase (l-histidinol-nad oxidoreductase, ec 1.1.1.23) from neurospora crassa. 2. the enzyme, as purified, has a sedimentation coefficient, s(20), of 7.1s and a molecular weight of 81 000. considerable variation is possible in the state of polymerization of the enzyme, giving rise to observed molecular weights from 40 000 to 240 000. 3. several kinetic parameters of the enzyme have been determined. the enzyme is maximally act ...19676033771
inositol biosynthesis in neurospora crassa. 19674383057
effects of edta on tyrosinase and l-amino-acid oxidase induction in neurospora crassa. 19674961897
nuclear division in neurospora crassa during conidiation and germination. 19674168108
altered protein formation as a result of suppression in neurospora crassa.the mutant td201 of neurospora crassa is mutated in the trp-3 locus and forms an altered tryptophan synthetase. a suppressor mutation, su2-6, in this mutant, unlinked to the trp-3 locus, results in the production of wild-type tryptophan synthetase activity, which accounts for the alleviation of the tryptophan or indole requirement. this enzyme activity is associated with a protein physically dissimilar to the wild-type enzyme. a second altered protein, a serologically cross-reacting material is ...19676025305
phenotypic reversal by 5-fluorouracil of the auxotrophy of am mutants of neurospora crassa. 19676036856
synchronous production of conidiophores and conidia of neurospora crassa. 19676039196
evidence for multiple forms of isocitrate lyase in neurospora crassa.the effect of carbon source on isocitrate lyase formation was studied in a wildtype strain of neurospora crassa and in a uridine-deficient mutant. a constitutive level of the enzyme was produced in a casein hydrolysate medium. the enzyme was repressed by glucose, although the two strains varied with respect to the degree of glucose repression. acetate strongly stimulated isocitrate lyase formation. the enzyme formed in the presence of acetate differed in several respects from that formed in gluc ...19676025448
inheritance of growth rate in neurospora crassa: reverse selection in an improved strain. 19675235104
[ribonucleases, phosphodiesterases and phosphomonoesterases in the culture of neurospora crassa under various conditions]. 19674294145
studies on the fungitoxicity of captan. v. electron microscopy of captan-treated neurospora crassa conidia. 19676041105
[active uptake of sugars by cells of neurospora crassa in the presence of an enzymatic system with permease properties i]. 19674384715
methylation of ethanolamine phosphatides by microsomes from normal and mutant strains of neurospora crassa. 19676016609
homocysteine and cysteine synthetases of neurospora crassa. purification, properties, and feedback control of activity. 19676016326
mutation-induced and nuclear inactivation in neurospora crassa using radiations with different rates of energy loss. 19676058651
the effect of nitrogen source and cysteine on the morphology, conidiation and a cell wall fraction of conidial and aconidial neurospora crassa. 19675600895
[metabolism of glycine and conidiation in neurospora crassa]. 19675591331
specificity in the photoreactivation of premutational damage induced in neurospora crassa by ultraviolet. 19675586545
[analysis of sorbose resistance in neurospora crassa in heterokaryons of sorbose resistant mutants; contribution to the genetics of active transport]. 19675586542
[crossing analysis of sorbose resistant mutants of neurospora crassa]. 19675586541
[analysis of sorbose resistance in neurospora crassa double mutants; contribution to the genetics of active transport. ii]. 19675584171
catabolite repression of malic dehydrogenase in neurospora crassa. 19676054686
deacetylation of n-acetyl-l-glutamic acid by neurospora crassa. 19676035272
effects of ph and temperature on the wild-type and a mutant form of neurospora glutamate dehydrogenase.1. we confirm the observation of bürk (1965) that neurospora crassa nadp-linked glutamate dehydrogenase normally exists in an inactive form below ph7.0 and in a fully active form above ph8.0 in either tris or orthophosphate buffer. at ph7.4 the enzyme is about half activated at 25 degrees . 2. the variety of the enzyme produced by the mutant am(2l) shows a similar behaviour except that the transition is shifted about one ph unit in the alkaline direction. 3. the am(2l) enzyme has previously been ...19676049385
synchronous mitochondrial division in neurospora crassa.samples of mycelium of neurospora crassa of known age were harvested from agar plates and examined with the electron microscope. the relative volume of the mitochondria was determined for mycelium of different ages. the volume measurements indicated that the mitochondria were dividing synchronously in fronts 6, 13, and 22(1/2) hr behind the growing hyphal tips. the sequence of mitochondrial division is hypothesized to include mitochondrial cupping followed by division which results in closely as ...19676064362
isolation of mutant strains of neurospora crassa from differentially surviving ascospores. 19675588793
enzyme activities during the asexual cycle of neurospora crassa. i. succinic dehydrogenase. 19676054680
the preparation and biochemical properties of mitochondria from neurospora crassa. 19676052632
an apparent relationship between mistranslation and an altered leucyl-trna synthetase in a conditional lethal mutant of neurospora crassa. 19676038419
[uptake of the sugars sorbose, fructose and glucose by sorbose-resistant mutants of neurospora crassa]. 19674384839
sorbose transport in neurospora crassa. 19676031493
quantitative and qualitative aspects of photoreactivation of premutational ultraviolet damage at the ad-3 loci of neurospora crassa. 19676026395
[possible presence of glycerol teichoic acid in neurospora crassa]. 19675622359
[active uptake of sugars by cells of neurospora crassa in the presence of an enzymatic system with permease properties ii]. 19674384716
genetic control of allelic recombination at the histidine-3 locus of neurospora crassa. 19676082625
the serine biosynthetic pathway in neurospora crassa. 19676077050
amino acid substitutions in mutant forms of histidinol dehydrogenase from neurospora crassa.amino acid changes in the enzyme l-histidinol dehydrogenase (l-histidinol-nad oxidoreductase, ec 1.1.1.23) have been determined between the wild-type neurospora crassa and two temperature-sensitive mutants. comparison was made between amino acid analyses of peptides of differing electrophoretic and chromatographic mobilities resulting from tryptic and chymotryptic digestion of protein from wild-type and mutant k26, and wild-type and mutant k445 strains, respectively. the analyses demonstrate the ...19676056636
the size distribution of x-ray induced multilocus deletions in the ad-3 region of neurospora crassa. 19675584575
"no-growth"-complementation in forced heterokaryons from sorbose-resistant (transport-defective) neurospora crassa mutants. 19674385815
involvement of a b-type cytochrome in the assimilatory nitrate reductase of neurospora crassa. 19674384346
3-deoxy-d-arabino-heptulosonic acid 7-phosphate synthetase as an "allosteric" function and ligand interactions with this enzyme from neurospora crassa. 19676064585
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