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[selective conidiogenic effect of thymine on a "serineless" mutant of neurospora crassa]. 19734269682
virus-like particles in an estranuclear mutant of neurospora crassa.a particulate fraction not present in wild-type cells has been isolated from the cytoplasm and from lysed mitochondria of the respiratory-deficient extranuclear mutant "abnormal-1" of neurospora crassa. the particles have a density between 1.13 and 1.2 g/ml. they appear in thin sections after oso(4) fixation as virus-like polymorphic vesicles containing an electron-dense nucleoid of 120-170 nm in diameter. the central core is surrounded by one or two "unit membrane" envelopes of 100 a thickness. ...19734268098
transport of c 4 -dicarboxylic acids in neurospora crassa. 19734268075
circular dichroism of a membrane protein of neurospora crassa. 19734703556
selection of respiratory mutants of neurospora crassa.a method is described that permits the isolation of mutants that are defective in mitochondrial respiration. the techniques of inositol-less death and overlay with 2,3,5-triphenyl-2h-tetrazolium chloride are utilized to select for mutant colonies. colonies that survive inositol-less death and fail to reduce the tetrazolium dye are then tested polarographically for cyanide-sensitive respiration. a preliminary characterization of three mutants obtained by this method is presented. the mutants have ...19734349028
genetic analysis of purple adenine (ad-3) mutants induced by methyl methanesulfonate in neurospora crassa. 19734348927
changes in enzyme activity of germinating conidia of neurospora crassa. 19734274506
interrelationships in trace-element metabolism in metal toxicities in a cobalt-resistant strain of neurospora crassa.a strain of neurospora crassa was isolated by training the mould to grow on media containing high concentrations of co(2+). this strain, the co(r) strain, exhibited approximately tenfold the resistance of the parent strain to co(2+) and ni(2+) but not to zn(2+) or cu(2+). co(2+) toxicity in the co(r) strain was reversed by mg(2+) but not by fe(3+). also, co(2+) did not affect iron metabolism in this strain. it is suggested that the mechanism of resistance in the co(r) strain involves an alterati ...19734269100
action of rec-3 on recombination near the amination-1 locus of neurospora crassa. 19734268716
role of lysine and -n-trimethyllysine in carnitine biosynthesis. i. studies in neurospora crassa. 19734266139
the inhibition of the neurospora crassa nitrate reductase complex by metal-binding agents. 19734144237
different chromatographic forms of neurospora crassa nucleases specific for single-stranded nucleic acids. 19734268627
[studies on the conidial differentiation of "neurospora crassa". v. ultrastructure of the macroconidiogenous sequence (author's transl)]. 19734138206
products of mitochondrial protein synthesis in neurospora crassa. determination of equimolar amounts of three products in cytochrome oxidase on the basis of amino-acid analysis. 19734359388
genetic characterization of ad-3 mutants induced by chemical carcinogens, i-phenyl-3-monomethyltriazene and i-phenyl-3,3-dimethyltriazene, in neurospora crassa. 19734271461
cellular compartmentation of aromatic amino acids in neurospora crassa. ii. synthesis and misplaced accumulation of phenylalanine in phen-2 auxotrophs. 19734270797
adenine nucleotide levels in neurospora, as influenced by conditions of growth and by metabolic inhibitors.by a combination of luciferase and fluorescence methods adenine nucleotide pools in neurospora crassa have been examined under various conditions of growth and metabolic inhibition. during sustained exponential growth (25 c, shaking liquid cultures), the intracellular adenosine 5'-triphosphate (atp) concentration, [atp](i), rises slowly from the conidial level near 1 mm (1 mmol/kg of cell water) to a maximum of 2.0 to 2.5 mm at 14 h, after which it slowly declines. the adenosine 5'-diphosphate a ...19734267534
the identification of a third b-galactosidase activity in neurospora crassa. 19734271074
changes in free and membrane-bound ribosomes during the vegetative growth of neurospora crassa. 19734272492
evidence for the existence of membrane-bound ribosomes in neurospora crassa. 19734272491
separation of the neutral carotenoids of neurospora crassa using concave gradient elution chromatography. 19734270371
repressible extracellular nucleases in neurospora crassa. 19734270540
mitochondrial protein synthesis and cyanide-resistant respiration in copper-depleted, cytochrome oxidase-deficient neurospora crassa. 19734356494
regulation of phosphate metabolism in neurospora crassa. characterization of regulatory mutants.a mutant of neurospora crassa, called uw-6, differs from wild type in being partially constitutive for synthesis of a species of alkaline phosphatase, and also for a species of phosphate permease that has a high affinity for phosphate at high ph. uw-6 is possibly allelic with a mutant called nuc-2 that was previously isolated by ishikawa. nuc-2 has the converse phenotype, in that it cannot be derepressed for either of these two activities. uw-6 is co-dominant with its wild-type allele in heterok ...19734271653
a search for complexity at the mating-type locus of neurospora crassa. 19734271649
influence of l-sorbose on the growth and morphology of neurospora crassa. 19734271185
the peptides of the hyphal wall of neurospora crassa. 19734271184
cellular compartmentation of aromatic amino acids in neurospora crassa. i. occupation of a protein synthesis pool by phenylalanine in tyr-1 mutants. 19734270570
mutation in neurospora crasa affecting some of the extracellular enzymes and several growth characteristics.a mutant of neurospora crassa, strain t9, which shows reduced activity of glucoamylase, was isolated. the mutant glucoamylase was not altered in ph optimum, or thermostability, but altered in elution profile of bio-gel filtration. the t9 mutation led to other distinct phenotypic effects: a poor growth response, resistance to the effect of sorbose, a high activity of extracellular acid phosphatase, and an increased sensitivity to high osmolarity of the growth medium. the discussion was based on t ...19734269585
cold-sensitive mutants of neurospora crassa.cold-sensitive mutants of the eucaryote neurospora crassa have been isolated by a modification of the filtration-enrichment technique of catcheside. the mutants include osmotic remedial, auxotrophic, transport, and incorporation deficient isolates.19734269583
inhibition of ribosomal rna synthesis during a shift-down transition of growth in neurospora crassa. 19734270631
[microbiological transformation of estrogens. transformation of equilenine into 12 beta-dihydroequilenine by neurospora crassa]. 19734276716
membrane-associated ribosomes in mitochondria of neurospora crassa. 19734271498
glucose utilization and ethanolic fermentation by wild type and extrachromosomal mutants of neurospora crassa.logarithmic growth rates, maximal biomass, specific glucose utilization rates, and ethanol accumulation were measured in aerobic cultures of wild type and extrachromosomal mutants of neurospora crassa. maximal biomass and ethanol accumulation of wild type and [mi-1] were proportional to the initial glucose concentration in the range of 2 to 10%. the specific rates of glucose utilization by the mutants were 13- to 20-fold greater than those of wild type in young cultures. the specific rates of gl ...19734270948
respiration of wild type and extrachromosomal mutants of neurospora crassa.the specific rates of respiration of cells of wild type and four extrachromosomal mutants of neurospora crassa were measured throughout the vegetative growth cycle. two forms of respiration were observed: (i) cyanide sensitive; and (ii) cyanide resistant, salicyl hydroxamate sensitive. these two forms are called terminal and alternate, respectively. the former proceeds by the mitochondrial electron transfer chain and involves the cytochromes; the latter apparently proceeds by the initial portion ...19734270947
the effects of nitrogen source upon respiration of neurospora crassa. 19734271970
characteristics of a transport-deficient mutant (nap) of neurospora crassa. 19734271482
transcription of non-repeated dna in neurospora crassa. 19734271645
altered mitochondrial respiration in a chromosomal mutant of neurospora crassa.a mutant of neurospora crassa (cni-1) has been isolated that has two pathways of mitochondrial respiration. one pathway is sensitive to cyanide and antimycin a, the other is sensitive only to salicyl hydroxamic acid. respiration can proceed through either pathway and both pathways together in this mutant account for greater than 90% of all mitochondrial respiration. the cni-1 mutation segregates as a nuclear gene in crosses to other strains of neurospora. absorption spectra of isolated mitochond ...19734355489
production of aminopurines and their nucleotides by neurospora crassa. 19734276003
the effect of thiourea on ureide metabolism in neurospora crassa.the wild-type strain of neurospora crassa em 5297a can utilize allantoin as a sole nitrogen source. the pathway of allantoin utilization is via its conversion into allantoic acid and urea, followed by the breakdown of urea to ammonia. this is shown by the inability of the urease-less mutant, n. crassa 1229, to grow on allantoin as a sole nitrogen source and by the formation of allantoate and urea by pre-formed mycelia of this mutant. in the wild strain (em 5297a) thiourea is tenfold more toxic o ...19734273557
effects of suppressor mutations on nonalleic glucose 6-phosphate dehydrogenase mutants of neurospora crassa. 19734270987
the neutral carotenoids of wild-type and mutant strains of neurospora crassa. 19734270986
the hyphal growth unit of wild type and spreading colonial mutants of neurospora crassa. 19734268673
growth of wild type and spreading colonial mutants of neurospora crassa in batch culture and on agar medium. 19734268672
correlation of growth inhibition patterns to nucleoside transport models in neurospora crassa.growth of inhibition patterns provide evidence for a common nucleoside transport or utilization system, a separate system or systems for adenine transport, and another adaptable mechanism of adenosine transport.19734270445
effects of glycine and serine on serine hydroxymethyltransferase levels in logarithmic cultures of neurospora crassa wild type and ser-1-mutant. 19734271349
sex-hormones in neurospora crassa: further studies on its biological properties. 19734270872
partial characterization of transfer rna genes isolated from neurospora crassa. 19734273106
role of the redox state of nicotinamide adenine dinucleotides in the in vivo regulation of inositol biosynthesis in neurospora crassa. 19734147849
cyclic 3',5'-amp phosphodiesterase of neurospora crassa. 19734354445
complementation analysis of metabolite-resistant mutations with forced heterokaryons of neurospora crassa.the double mutant strain pyr-3 arg-12(s) is a prototroph because a common precursor of arginine and pyrimidine is supplied by the arginine pathway. growth of this strain is inhibited by exogenous citrulline or arginine. citrulline-resistant mutants of this strain were selected, and they resulted from modifier mutations at other loci. forced heterokaryons were used to study complementation among these modifiers. since the complementation test requires the scoring of non-growth as the positive res ...197317248629
biochemical basis of radiation-sensitivity in mutants of neurospora crassa. 19734270666
tryptophan metabolism and kynureninase induction in mutants of neurospora crassa resistant to 4-methyl-tryptophan.mutants of neurospora crassa that are resistant to 4-methyl-tryptophan were found to differ in ability to synthesize kynureninase in the presence of the inducers kynurenine, 3-oh-kynurenine, n-formyl-kynurenine, tryptophan, and indole. one strain (mtr26), although incapable of accumulating intracellular pools of these compounds, showed induced synthesis of kynureninase, whereas the second (mtr21) could neither accumulate nor be induced by them. strain mtr21, with the suppressor su(mtr), could no ...19734269379
characterization of excision repair in neurospora crassa.the excision of pyrimidine dimers from the deoxyribonucleic acid (dna) of neurospora crassa was examined. postirradiation incubation in the presence of several chemicals known to inhibit various repair systems indicated that caffeine reduced the rate of excision twofold, but did not inhibit excision completely as did proflavine and quinacrine. examination of the time course of excision showed that repair occurs at a relatively rapid rate: approximately 60 dimers excised per min after 500 ergs/mm ...19734269375
action of single-strand specific neurospora crassa endonuclease on ultraviolet light-irradiated native dna. 19734270183
properties of chorismate synthase in neurospora crassa. 19734146266
mitochondrial translation products before and after integration into the mitochondrial membrane in neurospora crassa. 19734270056
enzymatic hydrolysis of penicillin g and other phenylacetylamino compounds by neurospora crassa acylase. 19734693635
branded chain amino acid aminotransferases of neurospora crassa. 19734268214
histidine uptake in mutant strains of neurospora crassa via the general transport system for amino acids.a transport double mutant of neurospora crassa has been isolated that has only one of the three transport systems capable of l-histidine uptake. the substrate specificity of the remaining transport system, termed the general transport system, has been fully characterized with regard to the contributions to binding of the side chain, the alpha-amino group, and the carboxylate group. the positively charged alpha-amino group is necessary for binding; the negatively charged carboxylate group is of l ...19734266243
regulation of glycogen phosphorylase a phosphatase in neurospora crassa. 19734350266
the isolation of the components of the anthranilate synthetase complex from neurospora crassa. 19734265643
aldosugar dehydrogenases from neurospora crassa partial purification and characterization of d-arabinose: nad dehydrogenase. 197311947073
insulin inhibition of membrane-bound adenylate cyclase in neurospora crassa. 197311947065
regeneration of invertase in neurospora crassa.in neurospora, invertase is predominately an extracellular enzyme, and acid phosphatase is partially external in location. both extracellular invertase and acid phosphatase were rapidly and quantitatively inactivated by acid treatment (ph 1.3). when such acid-treated cells were incubated with a suitable carbon source, a substantial regeneration of invertase activity occurred, but no restoration of acid phosphatase could be detected. the regeneration of invertase does not occur by renaturation of ...19734268689
structure and plugging of septa of wild type and spreading colonial mutants of neurospora crassa. 19734354924
electron microscopy of selectively stimulated microconidiogenesis in wild type neurospora crassa. 19734354923
lack of guanosine tetraphosphate accumulation during inhibition of rna synthesis in neurospora crassa. 19734269209
expression of the mitochondria genome in wild type and in extracellular mutants of neurospora crassa. 19734372151
alternative methods of preparation and analysis of quasicrystalline protein from neurospora crassa. 19734351946
the manipulation of mutation-induction kinetics in neurospora crassa. 19734726377
the relationship between atp and an electrogenic pump in the plasma membrane of neurospora crassa. 19734360924
enzymatic properties of a repressible acid phosphatase in neurospora crassa. 19734350735
[metabolic products of microorganisms. 120. uptake of iron by neurospora crassa. ii. regulation of the biosynthesis of sideramines and inhibition of iron transport by metal analogues of coprogen (author's transl)]. 19734272844
morphological mutants of neurospora crassa: possible evidence of abnormal morphology due to changes in dna composition. 19734272373
apparent effect of pentachloronitrobenzene on the hyphal wall polysaccharides of two strains of neurospora crassa. 19734272173
[studies on the conidial differentiation of "neurospora crassa". iv. chemo-structural modifications of the wall in the wild type and two aconidial mutants]. 19734269228
aryl sulfatase in ascospores of neurospora crassa.neurospora crassa ascospores normally do not contain aryl sulfatase even when formed under conditions of sulfur limitation. however, when one of the parental strains is the nonrepressible mutant scon(c), the resulting (mixed) ascospores contain significant levels of aryl sulfatase even when formed under conditions of sulfur abundance.19734265939
alkaline phosphatases of neurospora crassa. 3. effects of ph and mechanism of action. 19734265429
[metabolic products of microorganisms. 115. uptake of iron by neurospora crassa. i. to the specificity of iron transport]. 19734265135
acidic amino acid transport in neurospora crassa mycelia. 19734272502
the suppression of ad-3b mutants by supersuppressors in neurospora crassa.the action of eight suppersuppressors has been tested on 76 ad-3b mutants which were induced by base-pair transition mutagens. thirteen mutants were found to be suppressible by at least one ssu gene. most of the suppressible mutants were found to belong to a class in which one would expect to find nonsense mutants (polar complementing or noncomplementing classes, with at at the mutant site). however, suppression was observed in other classes, including those containing presumed missense mutants. ...19734360386
genetics of 5-fluorodeoxyuridine-resistant mutants of neurospora crassa. 19734273634
regulation of repressible alkaline phosphatase by organic acids and metal ions in neurospora crassa. 19734273558
isolation of circadian clock mutants of neurospora crassa.three mutants of neurospora crassa have been isolated which have altered period lengths of their circadian rhythm of conidiation. the strains, designated "frequency" (frq), were obtained after mutagenesis of the band (bd) strain with n-methyl-n'-nitro-n-nitrosoguanidine. in continuous darkness at 25 degrees bd has a period length of 21.6 +/- 0.5 hours; under the same conditions the period length of frq-1 is 16.5 +/- 0.5 hours; frq-2, 19.3 +/- 0.4 hours; and frq-3, 24.0 +/- 0.4 hours. each of the ...19734273217
a new map of the amination-1 locus of neurospora crassa, and the effect of the recombination-3 gene. 19734273092
rna polymerase activities in neurospora crassa. 19744277640
effects of ultraviolet radiation on carotenoid-containing and albino strains of neurospora crassa. 19744276420
hyphal tips of wild-type and spreading colonial mutants of neurospora crassa. 19744372967
membrane permeability and the loss of germination factor from neurospora crassa at low water activities.neurospora crassa conidia incubating in buffer at low water activities (a(w)) release a germination-essential component as well as 260-nm absorbing and ninhydrin-positive materials, regardless of whether an electrolyte or non-electrolyte is used to reduce a(w). chloroform and antibiotics known to increase cell-membrane permeability have a similar effect. this suggests that membrane damage occurs in media of low a(w) and that an increase in permeability is responsible for the release of cellular ...19744358044
nucleotide degrading enzymes in neurospora crassa. 19744282658
genetic contro of recombination in neurospora crassa. ii. polygenic and maternal control in two promimal chromosome regions - a quantitative analysis. 19744282487
hyperproduction of some glycosidases in neurospora crassa. 19744281648
uptake and efflux of sulfate in neurospora crassa. 19744276129
a study of l-glutamine: d-fructose 6-phosphate amidotransferase in certain developmental mutants of neurospora crassa. 19744275871
the biogenesis of mitochondria in neurospora crassa: ultrastructural changes induced by nutrients. 19744365709
mitochondrial translation of cytochrome b in neurospora crassa and locusta migratoria. 19744279883
lipid composition of mitochondrial outer and inner membranes of neurospora crassa. 19744279881
amino acid transport during development of neurospora crassa conidia: substrate repression. 19744275410
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