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localization of structural polymers in the cell wall of neurospora crassa.the distribution and localization of structural polymers in the cell wall of neurospora crassa has been studied by selective removal and light and electron microscope examination. observations with the light microscope indicated that each polymer by itself can provide structural integrity to the cell wall. examination by electron microscopy showed that the cell wall consists of an outer layer of thick fibrils, identified chemically as a glucan-peptide-galactosamine complex, and an inner layer ma ...19676055990
mitochondrial and cytoplasmic polysomes from neurospora crassa. 19676055444
loss of photorepair ability in conidia of neurospora crassa. 19676055393
mutagenicity of methylhydroxylamines in neurospora crassa. 20136054956
catabolite repression of malic dehydrogenase in neurospora crassa. 19676054686
enzyme activities during the asexual cycle of neurospora crassa. i. succinic dehydrogenase. 19676054680
the accumulation of argininosuccinate in neurospora crassa. ii. inhibition of arginyl-trna synthesis by argininosuccinate. 19676053229
the accumulation of argininosuccinate in neurospora crassa. i. elevated ornithine carbamoyl transferase with high concentrations of arginine. 19676053228
the preparation and biochemical properties of mitochondria from neurospora crassa. 19676052632
genetic control of the structure and activity of an enzyme aggregate in the tryptophan pathway of neurospora crassa. 19676052569
the role of iron in heme synthesis in neurospora crassa. 19676051578
effects of ph and temperature on the wild-type and a mutant form of neurospora glutamate dehydrogenase.1. we confirm the observation of bürk (1965) that neurospora crassa nadp-linked glutamate dehydrogenase normally exists in an inactive form below ph7.0 and in a fully active form above ph8.0 in either tris or orthophosphate buffer. at ph7.4 the enzyme is about half activated at 25 degrees . 2. the variety of the enzyme produced by the mutant am(2l) shows a similar behaviour except that the transition is shifted about one ph unit in the alkaline direction. 3. the am(2l) enzyme has previously been ...19676049385
the catabolism of l-arginine by neurospora crassa. 19676048315
studies on the fungitoxicity of captan. v. electron microscopy of captan-treated neurospora crassa conidia. 19676041105
a repressible acid phosphatase in neurospora crassa. 19676040372
thiamine-dependent accumulation of tetramethylpyrazine accompanying a mutation in the isoleucine-valine pathway.a mutant of corynebacterium glutamicum was found to accumulate high concentrations of a material which crystallized upon cooling of the broth. the compound was identified as tetramethylpyrazine. the mutant was found to require isoleucine, valine, leucine, and pantothenate for growth. all four requirements probably result from the loss of a single enzyme of the isoleucine-valine pathway. since similar mutants of neurospora crassa accumulate acetoin, the present mutant probably forms tetramethylpy ...19676039355
synchronous production of conidiophores and conidia of neurospora crassa. 19676039196
glutamic acid dehydrogenases in quiescent and germinating conidia of neurospora crassa. 19676038892
an apparent relationship between mistranslation and an altered leucyl-trna synthetase in a conditional lethal mutant of neurospora crassa. 19676038419
the effect of oxygen tension on growth, conidiation, and alcohol production of neurospora crassa. 19676036884
phenotypic reversal by 5-fluorouracil of the auxotrophy of am mutants of neurospora crassa. 19676036856
deacetylation of n-acetyl-l-glutamic acid by neurospora crassa. 19676035272
studies on malate dehydrogenases and aspartate aminotransferases from neurospora crassa. 19676035063
the purification and properties of histidinol dehydrogenase from neurospora crassa.1. a procedure is described for the purification of l-histidinol dehydrogenase (l-histidinol-nad oxidoreductase, ec 1.1.1.23) from neurospora crassa. 2. the enzyme, as purified, has a sedimentation coefficient, s(20), of 7.1s and a molecular weight of 81 000. considerable variation is possible in the state of polymerization of the enzyme, giving rise to observed molecular weights from 40 000 to 240 000. 3. several kinetic parameters of the enzyme have been determined. the enzyme is maximally act ...19676033771
sorbose transport in neurospora crassa. 19676031493
structure and composition of the cell wall of neurospora crassa.the structure and composition of the cell walls of hyphae of neurospora crassa were investigated by electron microscopy, chemical analysis, and x-ray diffraction both before and after progressive enzymatic degradation by snail gut enzymes, chitinase, and trypsin. the wall consists of two phases: randomly disposed skeletal microfibrils of chitin only and an amorphous matrix which contains both beta-glucans and protein. the protein contains a high percentage of the amides of aspartic and glutamic ...19676027990
quantitative and qualitative aspects of photoreactivation of premutational ultraviolet damage at the ad-3 loci of neurospora crassa. 19676026395
evidence for multiple forms of isocitrate lyase in neurospora crassa.the effect of carbon source on isocitrate lyase formation was studied in a wildtype strain of neurospora crassa and in a uridine-deficient mutant. a constitutive level of the enzyme was produced in a casein hydrolysate medium. the enzyme was repressed by glucose, although the two strains varied with respect to the degree of glucose repression. acetate strongly stimulated isocitrate lyase formation. the enzyme formed in the presence of acetate differed in several respects from that formed in gluc ...19676025448
regulation of glutamine synthetase. ii. patterns of feedback inhibition in microorganisms.the feedback inhibition of glutamine synthetase was investigated by use of partially purified enzyme preparations from salmonella typhimurium, micrococcus sodonensis, pseudomonas fluorescens, bacillus cereus, bacillus licheniformis, clostridium pasteurianum, rhodospirillum rubrum, neurospora crassa, candida utilis, and chlorella pyrenoidosa. inhibition analyses indicated that the enzyme of each organism can be effectively regulated with mixtures of end products from the diverse pathways of gluta ...19676025412
altered protein formation as a result of suppression in neurospora crassa.the mutant td201 of neurospora crassa is mutated in the trp-3 locus and forms an altered tryptophan synthetase. a suppressor mutation, su2-6, in this mutant, unlinked to the trp-3 locus, results in the production of wild-type tryptophan synthetase activity, which accounts for the alleviation of the tryptophan or indole requirement. this enzyme activity is associated with a protein physically dissimilar to the wild-type enzyme. a second altered protein, a serologically cross-reacting material is ...19676025305
methylation of ethanolamine phosphatides by microsomes from normal and mutant strains of neurospora crassa. 19676016609
homocysteine and cysteine synthetases of neurospora crassa. purification, properties, and feedback control of activity. 19676016326
[on the localization of inorganic polyphosphates and nucleotides in neurospora crassa mycelium]. 20135999969
[the dependence of p32 incorporation into mycelia of adenine deficient mutant of neurospora crassa on the concentration of adenine in the medium and on the presence of 8-azaadenine]. 19665995918
on the nature of folate derivatives of neurospora crassa and the effect of sulphanilamide. 19665989524
circadian nature of a rhythm expressed by an invertaseless strain of neurospora crassa.a new strain of neurospora crassa which exhibits a rhythm of conidiation when growing along an agar surface in a growth tube is described. the rhythm has been shown to be circadian for it meets the following criteria: a) the period under constant environmental conditions in the dark is about 24 hours (22.7 hours at 25 degrees ); b) the period is relatively temperature-independent (q(10) is between 0.95 and 1.21 for temperature range of 18 to 35 degrees ); c) the rhythm persists in continuous dar ...19665978549
carbon dioxide stimulation of the ad-3 mutants of neurospora crassa. 19665972694
purification and properties of ribonuclease n1, an extracellular ribonuclease of neurospora crassa. 19665972365
a study of conidiation in neurospora crassa. 19665971388
regulation of cellulase and cellobiase in neurospora crassa. 19665970513
a cytoplasmic variant of neurospora crassa. 19665968641
immunoelectrophoretic analysis of cytoplasmic proteins of neurospora crassa. 19665965359
on the in vitro development of pseudo-tryptophan synthase activity by extracts of neurospora crassa mutant strains td6 and td120. 19665961662
internuclear effects on prototroph frequencies of some crosses in neurospora crassa. 19665961489
interrelationships of sulfur amino acids in the pool and cellular protein of neurospora crassa. 19665961305
the dna content of centrioles of neurospora crassa during divisions i and iv of ascosporogenesis. 19665959217
tryptophan transport in neurospora crassa. i. specificity and kinetics.wiley, w. r. (battelle memorial institute, richland, wash.), and w. h. matchett. tryptophan transport in neurospora crassa. i. specificity and kinetics. j. bacteriol. 92:1698-1705. 1966.-the transport of tryptophan in neurospora crassa is mediated by a distinct stereospecific system which is chemically specific for a family of neutral amino acids. the process shows typical saturation kinetics and a sharp decrease in the rate of tryptophan uptake at low temperatures. the q(10) for the process is ...19665958105
neurospora crassa cytochrome c. ii. chymotryptic peptides, tryptic peptides, cyanogen bromide peptides, and the complete amino acid sequence. 19665950080
hybridization in vitro between wild-type and mutant forms of glutamate dehydrogenase from neurospora crassa. 19665947152
the dihydroxy acid dehydratase of neurospora crassa. 19665946629
a repressible alkaline phosphatase in neurospora crassa. 19665946607
evidence of a microsomal factor required for in vitro development of pseudo-triptophan synthase activity by extracts of neurospora crassa. 19665941363
cobalt toxicity and iron metabolism in neurospora crassa.1. increasing concentrations of cobalt in the medium result in increased production of an iron-binding compound and a corresponding fall in catalase activity of neurospora crassa. 2. cobalt rapidly depletes the medium of iron by enhancing the rate of iron uptake by the mycelium. 3. with toxic amounts of cobalt there is a fall in bound (59)fe and haem (59)fe as well as a decreased incorporation of [2-(14)c]glycine into the mycelial haem fraction. the production of the iron-binding compound preced ...19665938658
immunochemical and enzymatic studies and glutamate dehydrogenase and a related mutant protein from neurospora crassa.roberts, d. b. (university of cambridge, cambridge, england). immunochemical and enzymatic studies on glutamate dehydrogenase and a related mutant protein from neurospora crassa. j. bacteriol. 91:1888-1895. 1966.-when an investigation was made of the inhibition of neurospora glutamate dehydrogenase by bivalent and univalent antibodies, it was shown that the enzyme inhibition is not complete even with excess antibodies. the residual activity was some three times greater with bivalent antibodies, ...19665937244
susceptibility and resistance of several fungi to microbial lysis.potgieter, h. j. (cornell university, ithaca, n.y.), and m. alexander. susceptibility and resistance of several fungi to microbial lysis. j. bacteriol. 91:1526-1532. 1966.-strains of streptomyces, nocardia, and pseudomonas capable of lysing hyphae of fusarium solani or neurospora crassa were obtained by selective culture, but attempts to isolate an organism lysing rhizoctonia solani failed. when provided with f. solani or n. crassa as carbon sources, the actinomycetes tested produced beta-(1 --> ...19665929777
genetic alteration of pore size and other properties of the neurospora cell wall.trevithick, john r. (university of wisconsin medical school, madison), robert l. metzenberg and donald f. costello. genetic alteration of pore size and other properties of the neurospora cell wall. j. bacteriol. 92:1016-1020. 1966.-several properties of the cell walls of wild type and the osmotic mutant of neurospora crassa have been examined. the peameability of the isolated cell walls to polyethylene glycol and dextran polymers of different molecular weights was investigated by the volume of d ...19665926738
a new incompatibility locus in neurospora crassa. 19665919333
the utilization of leaky ad-3 mutants of neurospora crassa in heterokaryon tests for allelic complementation. 19665918504
neurospora crassa cytochrome c. i. purification, physical properties, amino acid composition, and peptide maps from "wild type" and "poky" strains. 19665912112
inositol deficiency resulting in death: an explanation of its occurrence in neurospora crassa.the incorporation of radio-active inositol and choline into the cytoplasmzic membranes of inositol-and choline-auxotrophic mnutants of neuros-pora crassa revealed that the membrane of particles which contain proteases is relatively poor in lecithin and rich in inositol-phospholipid. in mycelia of the mutant requiring inositol, grown in a suboptimum amount of exogenous inositol, the strlctural initegrity of the protease particles is lost, and the bulk of intracellular protease activity is recover ...19665908969
genetic control of amino acid permeability in neurospora crassa.lester, gabriel (reed college, portland, ore.). genetic control of amino acid permeability in neurospora crassa. j. bacteriol. 91:677-684. 1966.-strains of neurospora crassa resistant to 4-methyltryptophan (4-mt) were isolated from populations of conidia exposed to ultraviolet light. in genetic crosses, 4-mt resistance behaved as a single-gene difference. resistance to 4-mt could not be attributed to a relaxation of control of the formation or the activity of the enzymes of tryptophan biosynthes ...19665883112
growth responses of neurospora crassa to increased partial pressures of the noble gases and nitrogen.buchheit, r. g. (union carbide corp., tonawanda, n.y.), h. r. schreiner, and g. f. doebbler. growth responses of neurospora crassa to increased partial pressures of the noble gases and nitrogen. j. bacteriol. 91:622-627. 1966.-growth rate of the fungus neurospora crassa depends in part on the nature of metabolically "inert gas" present in its environment. at high partial pressures, the noble gas elements (helium, neon, argon, krypton, and xenon) inhibit growth in the order: xe > kr> ar > ne > he ...19665883104
[investigations on the biosynthesis of glycine in neurospora crassa, wild type and mutants]. 19655881618
identification of the genetic alterations in nitrous acid-induced ad-3 mutants of neurospora crassa. 19655878306
endogenous oxygen consumption by conidia of neurospora crassa. 19655878254
protection by 2-mercaptoethylamine against the mutagenic and lethal effects of x-rays in neurospora crassa. 19655878253
protection by endogenous anoxia against the mutagenic and lethal effects of x-rays in neurospora crassa. 19655878252
on the mechanism of intragenic recombination. ii. neurospora crassa. 19645875209
an extended model of periodic linkage in neurospora crassa. 19655868860
a ribonucleic acid fraction of neurospora crassa evoking development of a pseudo-tryptophan synthetase activity by extracts of mutants td-1, td-2, and td-3. 19655867005
karyokinesis of somatic nuclei of neurospora crassa. iv. the occurrence of the juvenile ring phase during division iv of ascosporogenesis. 19655866862
heterokaryon complementation among the pyridoxine auxotrophs of neurospora crassa. 19655866860
a cytoplasmic character in neurospora crassa. the role of nuclei and mitochondria.nuclear fractions isolated from mutants of neurospora produced no effect when microinjected into mutants with complementary biochemical requirements. dna isolated from the nuclear fractions similarly injected also had no effect. mitochondrial fractions isolated from an abnormal inositolless strain (abn-1) produced drastic changes in the rate of growth, morphology, reproductive characteristics, and cytochrome spectra of normal inositolless strains when single hyphal compartments were microinjecte ...19655865933
studies on a cytoplasmic character in neurospora crassa.two morphologically distinctive slow growing strains of neurospora crassa have been isolated and studied. these, abn-1 and abn-2, differ from wild type in that their growth rates are greatly reduced and often irregular, aerial hyphae are absent, conidia are extremely rare, and no protoperithecia are formed. growth was not improved by addition of any nutrients tested, oxygen consumption was similar to that of wild type, and cytochrome c appeared abnormally high, and b low or absent. both abn stra ...19655865932
[plate method for the determination of choline with a strain of neurospora crassa]. 19655864838
electrical properties of neurospora crassa. respiration and the intracellular potential.the internal potential of neurospora appears to have two components, one (a) which is reduced by anoxia or abolished by respiratory inhibitors such as azide and 2,4-dinitrophenol, and (b) a fraction that remains in the presence of respiratory inhibitors and is sensitive to the external potassium concentration. under standard conditions 1 mm azide or dinitrophenol diminishes internal potentials from near -200 mv to about -30 mv within 1 minute and at a maximal rate of 20 mv/second. the internal p ...19655862508
electrical properties of neurospora crassa. effects of external cations on the intracellular potential.glass micropipette electrodes have been employed to study the transsurface potential difference of neurospora crassa. for mature hyphae grown in agar cultures, the internal potential is large and negative, often exceeding -200 mv. the potential is sensitive to the concentrations of extracellular potassium, sodium, hydrogen, and calcium ions, but does not vary in a manner which is readily explained by ionic diffusion potentials. with extracellular solutions containing only potassium chloride (or ...19655862507
ribosomal nuclease activity of neurospora crassa. 19655862229
suppression of arginine and pyrimidine-requiring mutants of neurospora crassa. 19655861568
complementation pattern changes at the pyr-3 locus of neurospora crassa. 19655861567
carbamyl phosphate synthesis in neurospora crassa. ii. genetics, metabolic position, and regulation of arginine-specific carbamyl phosphokinase. 19655857368
carbamyl phosphate synthesis in neurospora crassa. i. preliminary characterization of arginine-specific carbamyl phosphokinase. 19655857367
studies on iron metabolism in neurospora crassa. 19655851867
relationship of the major constituents of the neurospora crassa cell wall to wild-type and colonial morphology.mahadevan, p. r. (the rockefeller institute, new york, n.y.), and e. l. tatum. relationship of the major constituents of the neurospora crassa cell wall to wild-type and colonial morphology. j. bacteriol. 90:1073-1081. 1965.-the relationship of cell wall to morphology in neurospora crassa was studied by correlating the levels of structural polymers of the cell wall with wild-type and colonial morphology. the cell wall of n. crassa contains at least four major complexes: a peptide-polysaccharide ...19655847797
the enzymatic conversion of anthranilate to indolylglycerol phosphate in neurospora crassa. 19655842052
molecular transport in neurospora crassa. i. biochemical properties of a phenylalanine permease. 19655840393
genetic control of nitrate reductase in neurospora crassa. 19655826322
studies concerning the biochemical genetics and physiology of activity and allosteric inhibition mutants of neurospora crassa 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase. 19695808705
analysis of ad-3 mutants induced by nitrous acid in a heterokaryon of neurospora crassa. 20135807326
an effect of genetic background on dose-response curves in neurospora crassa. 20135807325
the isolation of mutants affecting ascus development in neurospora crassa and their analysis by a zygote complementation test. 19695806169
locus-specific changes in cell wall composition characteristic of osmotic mutants of neurospora crassa.the osmotic phenotype of neurospora crassa is characterized by inhibition of growth at high osmolalities of growth medium. mutations at six osmotic loci of linkage group i were examined to assess the biochemical and physiological effects of these mutants. isolated cell walls from 23 osmotic strains were compared with the wild type with regard to quantitative levels of the following components: percentage of total dry weight, total glucose, alkali-soluble glucose, nonglucose carbohydrates, amino ...19695802619
organization of enzymes in the common aromatic synthetic pathway: evidence for aggregation in fungi.centrifugation in sucrose density gradients of partially purified extracts from six species of fungi, i.e., rhizopus stolonifer, phycomyces nitens, absidia glauca (phycomycetes), aspergillus nidulans (ascomycetes), coprinus lagopus, and ustilago maydis (basidiomycetes), indicate that the five enzymes catalyzing steps two to six in the prechorismic acid part of the polyaromatic synthetic pathway sediment together. the sedimentation coefficients for these enzymes are very similar in the six specie ...19695802608
crossing-over across the centromere in the mating-type chromosome of neurospora crassa. 19695800692
the control of allelic recombination at histidine loci in neurospora crassa. 19695799350
the mitochondrial and cytoplasmic transfer ribonucleic acids of neurospora crassa. 19695799126
variation in "map distance" in neurospora crassa. 19695798519
high frequency of 3:1 tetrad ratios for the pdx-1 locus of neurospora crassa. 19695797809
non-reciprocal recombination at the pan-2 locus in neurospora crassa. 19695797808
the gemini-xi s-4 spaceflight radiation interaction experiment. ii. analysis of survival levels and forward-mutation frequencies in neurospora crassa. 19695797679
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