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constitutents of egyptian euphorbiaceae. part 2: flavonoids of euphorbia paralias. 1976959303
phytochemical study of euphorbia paralias. 1976948535
constituents of egyptian euphorbiaceae iv investigation of euphorbia indica. 1977905435
triterpenes in latex of euphorbia pulcherrima. 1977905409
new highly irritant euphorbia factors from latex of euphorbia tirucalli l.from the latex of euphorbia tirucalli l. growing in madagascar, 5 new euphorbia factors were isolated. they were characterized as 13-o-acetyl-12-o-acylphorbol- and 12-o-acetyl-13-o-acylphorbol derivatives carrying homologous conjugated unsaturated fatty acids as acyl groups. furthermore, 2 mixtures of homologous 3-o-acylingenol derivatives are obtained carrying the same type of unsaturated fatty acids. due to their highly unsaturated acyl groups all euphorbia factors or factor groups isolated ar ...1977891836
crystalline principles of euphorbia terracina l. 1977594124
flavonoids of euphorbia geniculata and euphorbia prostata. 1977594128
historical note: drumine--a new australian local anaesthetic.an article in the australiasian medical gazette of october, 1886 indicates the method of extraction, experimentation and therapeutic application of an active principle, prepared from euphorbia drummondii. further correspondence is noted, refining the method of extraction, reporting cases, answering criticisms, and announcing eventually, drumine's commercial preparation. despite enthusiastic support, the drug soon disappears from the therapeutic scene.1977320904
candletoxins a and b, 2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, from the irritant latex of euphoria poisonii pax.2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, known as candletoxins a and b, were isolated from the irritant latex of euphorbia poisonii pax. compound a was identified as 12-deoxy-phorbol-13-o-phenylacetate-16-o-alpha-methyl-butyrate-20-acetate, and compound b was the c-20 desacetyl analogue.1977891875
the irritant toxins of blue euphorbia (euphorbia coerulescens haw). 1978622726
a note on the isolation and identification of two pharmacologically active constituents of euphorbia pilulifera. 1978642726
[molluscicidal properties of the euphorbia cotinifolia l (author's transl)].the hexanic extract from the leaves of euphorbia cotinifolia l. has been experimentally used as molluscicide against biomphalaria glabrata. the extract was fractionated and the most actives fractions were those of numbers 6 and 7. the lethal concentrations (lc50 and lc90 obtained using fraction 6 against adult snails were 1,2 and 2,4 ppm; for the eggs they were 25,0 and 48,0 ppm. with fraction 7 the lethal concentrations were 1,4 and 3,4 ppm for adult snails; for newly hatched snails they were 4 ...1978751112
a comparative study of antigens of aspergillus fumigatus isolates from patients and soil of ornamental plants in the immunodiffusion test.the strikingly frequent and constant presence of aspergillus fimigatus in the soil of potted ornamental plants kept in private houses and hospitals has been the reason for studying the antigens of the strains found from the diagnostic and epidemiological angles. culture-filtrate antigens of a. fumigatus strains isolated from the soil of 4 different ornamental plants, epiphyllum (epiphyllum truncatum), orange tree (citrus sinensis), alpine rose (azalea indica) and christmas flower (euphorbia pulc ...197883753
constituents of egyptian euphorbiaceae. part 6: phytochemical investigation of euphorbia geniculata jacq. and e. prostrata ait. 1978724788
[comparative study of herbal infusions of the spurges, euphorbia seguieriana, e. virgata and e. semivillosa, obtained by different methods]. 1978658352
cocarcinogenic and irritant factors of euphorbia esula l. latex.the latex of (euphorbia esula) has been found to contain highly skin irritant and inflammatory ingenol-3delta 2,4,6,8,10 pentene tetradecanoate and another factor, ingenol-3-dodecanoate, which is less irritating but which can be responsible for the cocarcinogenic activity exhibited by the latex preparation in the mice back skin experiment.1978653835
cytochemical studies on gerl, provacuoles, and vacuoles in root meristematic cells of euphorbia.the genesis of plant vacuoles has been studied by high-voltage and conventional electron microscopy. vacuole genesis is a lysosomal multistep process: (i) gerl (golgi-associated endoplasmic reticulum from which lysosomes apparently form) produces provacuoles into which lysosomal enzymes and probably other materials appear to be concentrated and packaged; (ii) gerl-derived provacuoles cooperate to drive a programmed cellular autophagy leading to young vacuoles; and (iii) the young vacuoles swell ...197816592499
a neglected mayan galactagogue, ixbut (euphorbia lancifolia). 197811619638
disappearance of porphobilinogen deaminase activity in leaves before the onset of senescence.the activity of porphobilinogen deaminase was measured in young and senescent or mature leaves of pepper (capsicum annuum), and poinsettia (euphorbia pulcherrima). whereas high activity was found in the crude extracts of the young leaves, almost no activity was found in the extracts of senescent or mature leaves. the decrease in deaminase activity was not due to the presence of an isolatable inhibitor. by purifying the crude enzyme extracts from leaves of different ages on deae-cellulose columns ...197916660874
specific inhibition of formation of acid-fastness in mycobacteria by 3,3'-di-o-methylellagic acid.3,3'-di-o-methylellagic acid obtained from euphorbia adenochlora selectively inhibited the formation of acid-fastness in mycobacteria without retardation of their growth. gross reductions in contents of wax d, cord factor and free mycolic acids were found in the nonacid-fast bacilli compared with the normal ones.197987342
dermatitis after exposure to a garden plant (euphorbia myrsinites).six pediatric cases of erythematous papulovescicular skin eruptions were due to exposure to euphorbia myrsinites. these rashes may be confused with allergies, infections, or other dermatoses. symptoms followed two to eight hours after exposure to the irritant sap, they increased in severity for an additional 12 hours, and they resolved within three to four days. no sequelae were noticed. treatment indicated was pain relief, prevention of infection, and reduction of swelling.1979760508
chemical investigation of local plants. part ii. triterpenoids of euphorbia wallichii hk.f. 1979419191
[antibacterial activity of preparations from the spurges, euphorbia seguieriana neck., e. virgultosa klok. and e. semivilliosa prokh]. 1979456524
constituents of egyptian euphorbiaceae. vii. further investigation of the flavonoids of euphorbia paralias l. 1979461577
characterization of an irritant 4-deoxyphorbol diester from euphorbia tirucalli.latex of euphorbia tirucalli, collected in colombia, yielded 12-o-2z-4e-octadienoyl-4-deoxyphorbol-13-acetate (1), which exhibited an irritant potency equivalent to that of the standard irritant, phorbol-12-tetradecanoate-13-acetate, in a mouse ear test system. the unsaturated 4-deoxyphorbol diesters recently reported in e. tirucalli grown in south africa were not observed in the present study.1979469552
gibberellins and the break of bud dormancy in virus-infected stem cuttings of euphorbia pulcherrima.break in bud dormancy in virus-infected stem cuttings of euphorbia pulcherrima occurs because of the higher quantity of gibberellins present in them than in healthy cuttings in the dormant period of the plant.1979499409
[studies on the active principles of ze-qi (euphorbia helioscopia l.), a drug used for chronic bronchitis (i) (author's transl)]. 1979506714
the succulent euphorbias of nigeria. iii. structure and potency of the aromatic ester diterpenes of euphorbia poissonii pax.the latex of euphorbia poissonii was found to contain irritant aromatic diterpene esters based upon resiniferonol, 12-deoxy-16-hydroxy-phorbol and 12-deoxyphorbol. four resiniferonol esters, 9,13,14-ortho-phenylacetyl-resiniferonol-20-0-[p-hydroxy-phenylacetate]; 9,13,14-orthophenylacetyl-resiniferonol-20-0-[m-methoxy-m'-hydroxy-phenylacetate]; 9,13,14-orthophenylacetyl-resiniferonol-20-0-acetate and resiniferonol-14-0-phenylacetate-20-0-[m-methoxy-m'-hydroxy-phenylacetate], were identified. two ...1979506740
inhibition of mitochondrial oxidative phosporylation by 4-deoxyphorbol triester, a poisonous constituent of the latex sap of euphorbia biglandulosa desf. 19807394805
screening of euphorbia from azarbaijan for skin irritant activity and for diterpenes. 19807367489
toxicity of fresh poinsettia (euphorbia pulcherrima) to sprague-dawley rats.fresh leaves and bracts of poinsettia (euphorbia pulcherrima) were fed to 46 sprague-dawley rats. the animals were observed for 1 week for changes in weight or behavior. the animals were then sacrificed in ether and examined for changes in thyroid and adrenal weights. one group was also examined for damage to the duodenum, jejunum, and ileum. no lesions or other signs of intestinal damage were observed. none of the groups showed any change in behavior or any significant change in body weight or ...19807398206
skin irritants of the sun spurge (euphorbia helioscopia l.).euphorbia helioscopia is a common herbaceous week found in the british isles and parts of europe. it has been responsible for poisoning of livestock resulting in severe inflammation particularly of mucous membranes and the eyes. four esters of 12-deoxyphorbol were isolated from the fresh aerial parts of the plant and their irritant doses 50% (i.d.50) ascertained using female l.a.c.a. mice, 12-deoxyphorbol-13-phenylacetate-20-acetate was found to be the major component of the toxic fraction and o ...19807389328
constituents of egyptian euphorbiaceae. ix. irritant and cytotoxic ingenane esters from euphorbia paralias l.the irritant and cytotoxic constituents of the latex of euphorbia paralias l. were separated from the hydrocarbon fraction by means of solvent partition. 3 new ingenane esters were identified from the toxic ether fraction. the major compound was 3-angelyl-20-deoxyingenol and the 2 minor compounds were 3-hexanoyl-20-deoxyingenol and 3-angelyl-ingenol. these compounds were of a similar potency to podophyllin in the inhibition of 3h-thymidine uptake by tlx/5 mouse lymphoma cells. in addition the co ...19807418805
[the effect of the sap of euphorbiaceae on the eye].ocular inflammations caused by the latex of euphorbiaceae manifest themselves as lid swelling, severe conjunctivitis, keratitis and iritis with hypopyon. as therapy, the local application of corticosteroids is recommended. in severely affected cases intravenous injections of sandosten-calcium and solu-dacortin (merck) are indicated. the caustic effect of euphorbia cyparissias is caused by phorbol acid and phorbol acid ester. on the canary islands, the latex of euphorbiaceae is quickly removed by ...19807421015
presence of a tumor-promoting factor in honey.honey samples collected from the saidabad area of azarbaijan province of iran were found to be moderately irritant, and this activity was associated with the presence of tri-acylates of the diterpene ingenol, which are transferred from the nectar of euphorbia seguieriana neck by honey bees to the honey. the acylates of ingenol are known promoters of carcinogenesis.19807429090
traditional medicine in health care.the state of research on plants used in traditional medicine and its development in egypt is indicated by the number of scientific institutions devoted to this problem: universities, the national research centre, the desert institute and the horticulture department of the ministry of agriculture. moreover, the use of certain medicinal plants has been "industrialised', e.g., ammi visnaga, cymbopogon proximus, nigella sativa and aloe vera. other plants are under investigation: urginea maritima, ph ...19807464176
oils and rubber from arid land plants.in this article the economic development potentials of cucurbita species (buffalo gourd and others), simmondsia chinensis (jojoba), euphorbia lathyris (gopher plant), and parthenium argentatum (guayule) are discussed. all of these plants may become important sources of oils or rubber.198017744536
the composition of a mixture of ingol esters from euphorbia kamerunica. 198117402067
effects of a 4-deoxyphorbol triester from the latex sap of euphorbia biglandulosa desf. on isolated spinach chloroplasts. 19817245219
dry column chromatographic procedure for rapid concentration of biological activity in natural products fractionation.a dry column chromatographic procedure is described. it allows for the rapid concentration of biologically active materials in natural products fractionation. the potential value of the technique is described, utilizing as an example the separation of an anticancer active fraction obtained from euphorbia cyparissias.19817264904
euphorbia peplus latex keratoconjunctivitis. 19817258972
testing for tumor promoters in euphorbia lathyris: analysis of possible health hazards. 19817337864
irritant contact dermatitis from an ornamental euphorbia.an ornamental succulent plant sold in many plant stores in the chicago area has been identified as euphorbia hermentiana lem. open and closed patch testing using undiluted latex from this species was performed on five caucasian volunteers. open testing on flexor forearms resulted in irritant follicular dermatitis, while closed testing to the flexor surfaces of both upper arms in each subject produced bullae and vesiculation with residual desquamation and hyperpigmentation. dermatological signs p ...19817249622
combined effect of the extracts from croton tiglium, euphorbia lathyris or euphorbia tirucalli and n-butyrate on epstein-barr virus expression in human lymphoblastoid p3hr-1 and raji cells.the combined usage of n-butyrate and 12-o-tetradecanoylphorbol-13-acetate (tpa) or the oily extracts from croton tiglium, euphorbia lathyris or euphorbia tirucalli exerted a marked effect on induction of epstein-barr virus (ebv)-associated early (ea) and viral capsid (vca) antigens in ebv genome-carrying human lymphoblastoid cell lines. in producer p3hr-1 cells, the enhancing effect of the 2 components was additive both for ea and vca, while in non-producer raji cells, a synergistic increase of ...19816266651
tumor promoting and skin irritant diterpene esters of euphorbia virgata latex.the mouse ear irritant latex of e. virgata, has been found to contain various skin irritant and non-irritant esters of the diterpene ingenol. in cocarcinogenic assay on dorsal back skin of nmri mice, acetone extract of this latex produces squamous cell papilloma. using a combination of biologic and chemical separation techniques one of the initiator-promotor for skin carcinogenesis has been identified as 3-0-2 methyl-decanoyl ingenol.19816458773
epinasty of poinsettias-the role of auxin and ethylene.upward physical restraint of the normally horizontal bracts of poinsettia (euphorbia pulcherrima willd.) resulted in increased ethylene production and epinastic curvature of the petioles after 5 days. downward restraint caused little change in ethylene production or epinasty, indicating that the enhanced ethylene production observed in petioles bent upwards is not due to the bending stress alone. epinasty, measured upon removal of upward physical restraint, was not affected by spraying plants wi ...198116661798
[constituents of euphorbiaceae, 7. 20-deoxyingenol monoesters and ingenol diesters from euphorbia biglandulosa desf]. 19827159190
skin irritant ingenol esters from euphorbia esula. 19827163415
purification and properties of diamine oxidase from euphorbia latex.a diamine oxidase has been purified to homogeneity from the latex of an herbaceous shrub, euphorbia characias. this enzyme has a relative molecular mass of 144,000 and is composed of two identical subunits. it contain two cu(ii) and two carbonyl-like groups per dimer. the purified enzyme is pink and shows a broad absorption in the visible region centered at 480 nm, which is modified by the addition of phenylhydrazine or semicarbazide. the electron paramagnetic resonance spectrum is typical of co ...19826814913
a neglected mayan galactagogue - ixbut (euphorbia lancifolia).a herbal tea, made of leaves of ixbut (euphorbia lancifolia schlecht.), has been used for several centuries by postpartum mayan women in guatemala to stimulate and increase the flow of mother's milk. ixbut, when mixed with cattle fodder, is reputed to have increased milk yields in cows. to date, the active principle of ixbut has never been isolated. however, this medicinal herb, a natural galactagogue of central american origin, would appear to be worthy of further chemical and pharmacological s ...19827033669
on the active principles of the spurge family (euphorbiaceae). iv. skin irritant and tumor promoting diterpene esters from euphorbia ingens e.mey.the irritant and tumor-promoting principles of the latex of euphorbia ingens e. mey have been isolated together with several nonirritant compounds. the euphorbia factors i1, i5, and i6 are esters of ingenane-type poly-functional diterpene alcohols. euphorbia factor i1 is characterized as the 3-hexadecanoate of the polyfunctional parent alcohol ingenol and euphorbia factor i6 as the 3-deca-2.4.6-trienoic acid ester of ingenol. euphorbia factor i5 is the 16-angelate-3-deca-2.4.6-trienoate of 16-hy ...19827118989
the dermatitis-producing constituents of euphorbia hermentiana latex.five ingenane derivatives, 3-o-n-(deca-2,4,6-trienoyl)-16-o-[(z)-2-methyl-2-butenoyl]-16-hydroxyingenol (1), 3-o-[(z)-2-methyl-2-butenoyl]-5,16,20-o-triacetyl-16-hydroxyingenol (2), 3-o-[(z)-2-methyl-2-butenoyl]-16,20-o-diacetyl-16-hydroxyingenol (3), 3-o-[(z)-2-methyl-2-butenoyl]-20-o-acetylingenol (4), and 3-o-[(z)-2-methyl-2-butenoyl]-16-o-acetyl-20-deoxy-16-hydroxyingenol (5) were isolated with a new procedure that uses droplet counter-current chromatography, from a dermatitis-producing frac ...19836655474
purification and properties of two lectins from the latex of the euphorbiaceous plants hura crepitans l. (sand-box tree) and euphorbia characias l. (mediterranean spurge).1. from the latex of two members of the plant family euphorbiaceae, hura crepitans l. (sand-box tree) and euphorbia characias l. (mediterranean spurge), two lectins were purified by affinity chromatography on acid-treated sepharose 6b followed by elution with d-galactose. 2. the lectin from e. characias is a single molecular species with mr 80 000, made up of two identical subunits with mr 40 000, and is a glycoprotein containing 11% carbohydrate. 3. the lectin from h. creptians appears as a mix ...19836661180
pichia euphorbiae sp. nov., a new haploid heterothallic yeast species.representatives of an undescribed, haploid, heterothallic yeast species, pichia euphorbiae, have been recovered from insect-infested specimens of euphorbia ingens. the new species is considered to be another representative of the apparently related group of heterothallic species, comprising pichia rhodanensis, pichia wickerhamii, pichia veronae, pichia amylophila, pichia mississippiensis and pichia meyerae. while no mating response was observed in interspecific mixtures of the mating types of th ...19836614897
isolation and partial characterization of a lectin from euphorbia heterophylla seeds.an n-acetylgalactosamine-specific lectin was isolated from euphorbia heterophylla seeds by affinity chromatography on cross-linked arabinogalactan. it is a dimeric protein of two identical subunits of mr 32 000, and differs structurally from all previously known euphorbiaceae lectins. its distribution over the seed is typical in that it is merely confined to the primary axes.19836626171
essential sulfhydryl groups in diamine oxidase from euphorbia characias latex.diamine oxidase from euphorbia characias latex contains two sulfhydryl groups per mole of dimeric enzyme. the sulfhydryl groups are unreactive in the native enzyme but can be readily titrated by 4,4'-dithiodipyridine after protein denaturation, or anaerobically in the presence of the amine substrate. in the presence of both substrates (diamine and oxygen) they react sluggishly. the sulfhydryl groups show different reactivity toward various reagents, but in every case their modification inhibits ...19836401986
anti-inflammatory activity of euphorbia acaulis roxb.from various extracts of euphorbia acaulis , the n-hexane fraction showed marked anti-inflammatory activity in carrageenan induced oedema in rats and mice as compared to phenylbutazone and was equipotent in adrenal- ectomised rats. in chronic models of formaldehyde and adjuvant arthritis, its anti-arthritic activity was found to be superior to that of phenylbutazone. it had a diuretic effect but did not show any analgesic or antipyretic activity.19846727400
effects of euphorbia prostrata and fumaria parviflora in normoglycaemic and alloxan-treated hyperglycaemic rabbits. 19846473545
macrocyclic lathyrane type diterpene esters (jolkinols) from callus cultures and roots of euphorbia lathyris. 19846484031
correlation of the anticholinesterase and molluscicidal activity of the latex of euphorbia royleana on the snail lymnaea acuminata. 19846491683
alteration in biogenic amine levels in the snail lymnaea acuminata by the latex of euphorbia royleana.the latex of euphorbia royleana which has high molluscicidal and anti-cholinesterase activity against lymnaea acuminata reduced the levels of 5-hydroxytryptamine (5ht) and dopamine (da) in the nervous tissue of l. acuminata. there was, however, no significant change in the level of 5-hydroxyindole acetic acid (5hiaa). the changes were found to be dependent on concentration of the latex extract. similar changes were produced by both water and organic solvent extracts of the latex. the latex of e. ...19846204425
function of the lower intestine and osmoregulation in the ostrich: preliminary anatomical and physiological observations.the gross anatomy of the lower intestine of the african ostrich (struthio camelus) was investigated in four adult birds shot in the wild. the presence of 80 cm long paired caeca, and approximately 10 m of colon between ileum and the cloaca was confirmed. urine, but not faeces, was found in the coprodeum. retrograde flow into the colon was not observed. samples of contents from the lower intestine were secured from these birds and the water content, osmolality and concentrations in the supernatan ...19846514998
[antineoplastic effect of euphorbia fischeriana steud on mice with implanted tumor]. 19846233041
active principles of the euphorbiaceae. vii. milliamines h and i, peptide esters of 20-deoxy-5 epsilon-hydroxyphorbol from euphorbia milii. 19846517976
use of potato disc and brine shrimp bioassays to detect activity and isolate piceatannol as the antileukemic principle from the seeds of euphorbia lagascae.etoh extracts of the seeds of euphorbia lagascae inhibited crown gall tumors on potato discs, were active against 3ps (in vivo) and 9ps (in vitro) mouse leukemia, and were toxic to brine shrimp. using the potato disc and brine shrimp bioassays to monitor fractionation, piceatannol (3,4,3',5'- tetrahydroxystilbene ) was isolated as the 3ps active principle. aesculetin (6,7-dihydroxycoumarin) was isolated in large quantity, was weakly cytotoxic in 9kb , but was inactive in the other bioassay syste ...19846736971
tumor promoting activity of euphorbia striatella (boiss) and skin irritant activity of some euphorbia species.out of seven plants selected due to their use in folk medicine, five possessing ingenol as diterpene parent, exhibited mild skin irritancy where as e. striatella latex was highly skin irritant and produced papilloma, in initiation-promotion experiment on mouse back skin. this tumor promoting activity has been demonstrated due to the presence of ingenol-3-o-decanoate.19846738758
on the active principles of the spurge family (euphorbiaceae). v. extremely skin-irritant and moderately tumor-promoting diterpene esters from euphorbia resinifera berg.the irritant and tumor-promoting principles were isolated from the latex of euphorbia resinifera berg. and from the resin derived from latex (euphorbium), which is commercially available as a drug. the irritant euphorbia factors rl 5 (mixture), rl 6, rl 7, rl 8, and rl 10 were identified as tigliane-type 12-deoxyphorbol esters each bearing, in the 13 position, either long-chain, partially methyl-substituted acyl residues (10-16 carbon atoms) or short-chain acyl residues (4 or 5 carbon atoms) or ...19846746723
isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase from guayule (parthenium argentatum gray).electron micrographs of the mesophyll cells of guayule parthenium argentatum gray leaves show deposits of cis-polyisoprene (rubber) in the cytoplasm in the vicinity of mitochondria and chloroplasts and demonstrate that the rubber-synthesizing enzymes are present in guayule leaves. the terminal step in the synthesis of cis-polyisoprene from isopentenyl pyrophosphate (ipp) catalyzed by isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase has been demonstrated in crude leaf extracts by the e ...198416663758
plant antiviral agents; vi.1 3-methoxyflavones as potent inhibitors of viral-induced block of cell synthesis.an investigation of the constituents responsible for the pronounced antiviral activity observed for extracts of euphorbia grantii oliv. stems has afforded four related 3-methoxyflavones exhibiting remarkable activities against picornaviruses and vesicular stomatitis virus. all compounds were found to be derivatives of 3-methylquercetin. the concentration of 3-methylquercetin (3-mq) and 3,3'-dimethyl-quercetin (3,3'-dmq) inhibiting 90 % of polio type 1 and coxsackie b4 viruses in tissue culture w ...198417340366
structure activity relations of polyfunctional diterpenes of the tigliane type, vi1.a method for the isolation and preparation of 12-deoxyphorbol ( 1) from euphorbium resin ( euphorbia resinifera berg) was established to provide substantial amounts of 1-esters for bioassays. acylation of 1 yielded 12-deoxyphorbol-13,20-diesters ( 2, esters with acids ch (3)(ch (2)) (n)cooh, n = 0, 4, 8, 12, 16, 20; and with benzoic, oleic, elaidic and linoleic acid). upon mild transesterification the 13,20-diesters 2 yielded the 13-monoesters 3. both ester types were tested for their irritant a ...198417340253
histopathology of okra and ridgeseed spurge infected with meloidodera charis.histological observations of okra abelomoschus esculentus 'clemson spineless' and ridgeseed spurge euphorbia glyptosperma (a common weed) infected with meloidodera charis hopper, indicated that the juvenile nematode penetrated the roots intercellularly. within 5 days after plant emergence the nematode positioned its body in the cortical tissue parallel to the vascular system. by 10 days after plant emergence the juvenile had extended its head into the vascular system and initiated giant cell for ...198419295883
effect of drying on yield and calorific values of extractables from leafy spurge (euphorbia esula).the effect of dehydration on yield and calorific values has been investigated for oils, hydrocarbons, and polyphenols extracted from leaves of euphorbia esula/ (leafy spurge). methods of dehydration employed were with a warm oven (50 degrees c), a hot oven (105 degrees c), at room temperature (25 degrees c), and with freeze drying. generally, dehydration resulted in a loss of yield for all extractives. noteworthy exceptions were oil yields from the warm-oven- or air-dried biomass which did not d ...198418553299
isolation of prostratin from euphorbia cornigera. 198517340537
photosynthetic responses to dynamic light environments by hawaiian trees : time course of co(2) uptake and carbon gain during sunflecks.gas exchange responses to rapid changes in light were studied in a c(3) tree, claoxylon sandwicense muell-arg and a c(4) tree, euphorbia forbesii sherff that are native to the understory of a mesic hawaiian forest. when light was increased to 500 micromoles per meter per second following a 2 hour preexposure at 22 micromoles per meter per second, net co(2) uptake rates and stomatal conductance gradually increased for over 1 hour in c. sandwicense but reached maximum values within 30 minutes in e ...198516664512
[euphorbiae keratoconjunctivitis].this paper reports on 6 cases of keratoconjunctivitis caused by the latex of euphorbiaceae, one of them with slight systemic intoxication. phorbolesters are considered to be responsible for the toxicity of the latex of euphorbiaceae, e.g., in the case of euphorbia helioscopia, 12-desoxyphorbol-13-phenylacetate-2-o-acetate. since all of the cases of keratoconjunctivitis euphorbiae described here, as well as the majority of those cited in the literature, have resulted in a restitutio ad integrum, ...19854021430
irritant dermatitis due to euphorbia marginata. 19854042646
contact dermatitis from euphorbia pulcherrima. 19853161691
on the active principles of the spurge family (euphorbiaceae). xi. [1] the skin irritant and tumor promoting diterpene esters of euphorbia tirucalli l. originating from south africa.the irritant and tumor-promoting constituents of latex of euphorbia tirucalli l. originating from south africa were isolated. they were identified as irritant ingenane and tigliane type diterpene esters derived from unsaturated aliphatic acids and acetic acid and the polyfunctional diterpene parent alcohols 4-deoxyphorbol, phorbol and ingenol, respectively. the irritant and tumor-promoting esters of 4-deoxyphorbol are predominant and were fully characterized chemically and biologically. they are ...19854082727
molluscicide activity of the "avelós" plant (euphorbia tirucalli, l.) on biomphalaria glabrata, the mollusc vector of schistosomiasis.an aqueous solution of the latex of euphorbia tirucalli collected at sites receiving large amounts of sunlight showed molluscicide action on biomphalaria glabrata, with ld50 obtained at the concentration of 28,0 ppm and ld90 at the concentration of 85,0 ppm. the toxicity of the product for fish was similar to that of bayluscide and of copper sulfate used for comparison. however, the wide distribution of the plant, its easy propagation and the simple procedure for extraction of the active substan ...19853939311
latex of "coroa de cristo" (euphorbia splendens): an effective molluscicide.an aqueous solution of the latex of "coroa de cristo" (euphorbia splendens var. hislopii) showed molluscicide action (ld90) at a concentration lower than 0.5 ppm on biomphalaria glabrata and b. tenagophila reared in laboratory and at a concentration lower than 4.0 ppm for field b. tenagophila.19863613981
[euphorbia and high chapparall--hazardous pot plants in fashion]. 19863747661
epstein-barr virus-enhancing plant promoters in east africa.the extracts of a certain african plant species, euphorbia tirucalli, were found to have markedly enhancing effects on the activation of latent epstein-barr virus (ebv) genomes in the ebv carrying lymphoblastoid cells and also on ebv-induced transformation of human lymphocytes. the euphorbia tirucalli was especially noticeable in highly endemic areas of burkitt's lymphoma (bl), an ebv-associated malignancy, in kenya and tanzania. the activation of the latent ebv genome and the ebv-induced transf ...19863030344
on the active principles of the euphorbiaceae, xii. highly unsaturated irritant diterpene esters from euphorbia tirucalli originating from madagascar.the latex of euphorbia tirucalli originating from madagascar contains as irritant constituents ingenane- and tigliane-type diterpene esters derived from the parent alcohols ingenol and phorbol. the main irritant constituents are isomeric 12,13-acetates, acylates of phorbol as well as 3-acylates of ingenol. as acyl groups, they carry homologous, highly unsaturated aliphatic acids of the general structure ch3-(ch2)m-(ch = ch)n-cooh (m = 2,4; n = 2,3,4,5; total number n of c-atoms = 2n + m + 2). th ...19863760879
[mutagenic evaluation of the chinese drug c, l, t, g pill consisting of daphne genkwa, euphorbia kansui, euphorbia pekinensis, glycyrrhiza uralensis tested in salmonella typhimurium and b. subtilis]. 19862952328
3-methylquercetin is a potent and selective inhibitor of poliovirus rna synthesis.3-methylquercetin (3mq) is a natural compound isolated from euphorbia grantii that selectively inhibits poliovirus replication, but has no effect on encephalomyocarditis virus. when the compound is present from the beginning of infection, the bulk of viral protein synthesis is prevented, but the shut-off of host protein synthesis still occurs. addition of 3mq 3 hr after infection has a slight effect on viral protein synthesis, suggesting that this compound blocks a step of viral replication diff ...19863012868
no latex starch utilization in euphorbia esula l.utilization of leaf, stem, root, and latex starch was monitored in euphorbia esula l. plants. leaf, stem, and root starch decreased rapidly during a 52 day light starvation period while latex starch did not. scanning electron and light microscope studies provided additional evidence that no changes in latex starch granules had occurred. amylase activity (6.6 units per milligram protein) could be isolated from latex. however, latex starch granules were extremely resistant to enzymic hydrolysis by ...198616664883
triterpene biosynthesis in the latex of euphorbia lathyris: effect of calmodulin antagonists and chlorinated phenoxy compounds.recognized calmodulin antagonists and chlorinated phenoxyalkylamines were tested as inhibitors of mevalonate incorporation into triterpenols and their fatty acid esters in a centrifuged pellet from the latex of euphorbia lathyris. the calmodulin antagonists, chlorpromazine (ii), fluphenzine, and trifluoperazine were good inhibitors; i(50) values for ii and trifluoperazine were 150 and 55 micromolar, respectively. inhibition by the phenoxyalkylamines increased with increasing chlorine substitutio ...198716665197
triterpene biosynthesis in the latex of euphorbia lathyris: calmodulin antagonists are ineffective in whole latex.the calmodulin antagonists chlorpromazine, fluphenazine, trifluoperazine, and 2-(pentachlorophenoxy)ethyl n,n-diethylamine are not inhibitors of acetate incorporation into triterpenols (toh) and their fatty acid esters (te) in whole tapped latex from euphorbia lathyris, although prior work demonstrated that these antagonists are good inhibitors of mevalonate incorporation into toh and te in a centrifuged pellet from the latex. antagonist absorption into the endogenous terpene pool is the primary ...198716665198
euphorbia escula l. root and root bud indole-3-acetic acid levels at three phenologic stages.endogenous indoleacetic acid (iaa) levels of euphorbia esula l. primary root and root buds were examined at three phenologic stages. high performance liquid chromatography coupled with fluorescence detection and gas chromatography-mass spectrometry, using (13)c(6)[benzene ring]-indole-3-acetic acid as internal standard, were used to measure root bud free and bound iaa levels in vegetative, full flower, and post-flower plants. highest levels of free iaa (103 nanograms per gram fresh weight) were ...198716665432
effects of coal-smoke pollutants from different sources on the growth, chlorophyll content, stem anatomy and cuticular traits of euphorbia hirta l.variations occurred in the growth, assimilate partitioning, chlorophyll content, stem anatomy and leaf cuticular traits of euphorbia hirta l. on long-term exposure to coal-smoke pollutants prevailing at two sites, one situated close to a railway loco shed (site b) and another in the vicinity of a thermal power plant (site c). the botanical garden of aligarh muslim university, aligarh, was considered as a control site (a). site c possessed a greater load of coal-smoke pollutants than site b. the ...198715092709
[isolation and identification of the lipophilic constituents from the root of euphorbia fischeriana steud]. 19873442914
3,3',5'-tri-o-methylpiceatannol and 4,3',5'-tri-o-methylpiceatannol: improvements over piceatannol in bioactivity.piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) (nsc 365798) has recently been isolated and was subsequently synthesized for nci tumor panel testing as a new antileukemic natural product from the seeds of euphorbia lagascae. during the synthesis, a bioactive reaction mixture of several partially o-methylated piceatannol analogues was obtained. this mixture has now been maximized and subjected to bioactivity-directed fractionation, using brine shrimp lethality, to yield 3,3',5'-tri-o-methylpi ...19873598597
african burkitt's lymphoma and an epstein-barr virus-enhancing plant euphorbia tirucalli. 19872884382
further triterpenes from the stem bark of euphorbia tirucalli. 198717269106
triterpenoids from the latex of euphorbia caudicifolia. 198817265336
quantitative determination of polyfunctional diterpene esters of the ingenane type in euphorbia lathyris by hplc. 198817265381
weed hosts of meloidogyne arenaria and m. incognita common in tobacco fields in south carolina.thirty-two weed species common in south carolina and one cultivar of tobacco were evaluated as hosts of meloidogyne arenaria race 2 and m. incognita race 3 in the greenhouse. egg mass production and galling differed (p < 0.05) among weed species. chenopodium album, euphorbia maculata, and vicia villosa were good hosts of m. arenaria. amaranthus palmeri, rumex crispus, amaranthus hybridus, ambrosia artemisiifolia, lpomoea hederacea var. integriuscula, setaria lutescens, sida spinosa, portulaca ol ...198819290313
screening extracts of euphorbia garuana n.e.br. for in-vitro cytotoxicity.two biological assays utilising in-vitro uptake of 3h-thymidine into tlx/5 lymphoma and rat basophilic leukaemia cells have been used for rapid detection and subsequent isolation of active compounds from the latex of euphorbia garuana (euphorbiaceae). two potent esters were characterized from the latex of e. garuana reportedly used in traditional medicine for the treatment of certain forms of cancer.19882854369
[isolation and identification of antitumor constituents of diterpenoids lactone in euphorbia fischeriana steud]. 19883197209
irritant principles of the spurge family (euphorbiaceae). xiii. oligocyclic and macrocyclic diterpene esters from latices of some euphorbia species utilized as source plants of honey.the latices of the three south african species euphorbia ledienii, euphorbia coerulescens, and euphorbia triangularis, belonging to a group of cactiform euphorbias locally called "noors," were shown to contain four 12-mono- and three 13,20-diesters of the tetracyclic tigliane type parent alcohol 12-deoxyphorbol [1]. in addition, two 13,16-di- and two 13,16,20-triesters of the related 12-deoxy-16-hydroxyphorbol [9] were obtained. ester groups in 1 and 9 are made up of acetic, isobutyric, tiglic, ...19883236005
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