Publications

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[pharmacology of total flavonoids from euphorbia palustris l]. 19734767380
[on the presence of rhamnetine in the genus euphorbia. a correction (author's transl)]. 19744818019
[dermatitis caused by a decorative plant, euphorbia variegata]. 19744830662
clinical studies of euphorbia acaulis, rox b. in cases of eczema--a preliminary report. 19714935910
preliminary phytochemical investigation of euphorbia millii. 19725046121
chemical examination of euphorbia myrsinitis linn. 19725059805
euphorbia royleana latex keratitis. 19725075134
euphorbia pulcherrima: toxicity to rats. 19715092399
further new diterpene esters from the irritant and cocarcinogenic seed oil and latex of the caper spurge (euphorbia lathyris l.). 19715144835
[euphorbia palustris and stepposa flavonoids and their pharmacological properties]. 19715150542
[effect of total euphorbia sequiriana flavonoid on the cardiovascular system and intestinal smooth muscle]. 19715150838
injury to the eye by the sap of euphorbia royleana. 19715159815
[flavonoids from swamp and steppe spurges and their pharmacological properties]. 19715163056
new constituents of euphorbia resinifera berg. 19695381552
[note on 2 african drugs with confirmed amebicidal properties: holarrhens floribunda and euphorbia hirta]. 19695399292
tumor-promoting compounds from euphorbia cooperi di- and triesters of 16-hydroxy-12-desoxy-phorbol. 19705417593
[flavonol glycosides of euphorbia amygdaloides and their quantitative determination at various stages of plant development. 5. flavonoids of native euphorbiaceae]. 19705439745
[dermatitis due to euphorbia rigida m.b]. 19705496838
[synthesis of glucuronides in the flavonoid series. ii. isolation of kaempferol-3-beta-d-glucuronide from euphorbia esula l]. 19705522586
[flavonolglycosides from euphorbia myrsinitis. their isolation and identification. 6. flavonoids of native euphorbiacae]. 19715547621
study of the laxative action of euphorbia lathyris seed oil. 19675592106
[polyphenol compounds of euphorbia palustris]. 19675600230
euphorbia esula l. (euphorbiaceae). i. preliminary phytochemical and biological evaluation. 19685671340
[flavonoids of euphorbia stepposa]. 19685699876
carbon dioxide compensation points in related plant species.both high and low c0(2) compensation concentrations were found in the plant genera-panicum, cyperus, and euphorbia. within each genus, however, high and low compensations were found in different subgenera. thus, they may not be genetically closely related. no significant differences in co(2) compensation were found among 100 genetic lines of triticum aestivum l. or among 20 lines of hordeum vulgare l.19695774193
tumor promoting compounds from euphorbia triangularis: mono- and diesters of 12-desoxy-phorbol. 19695820946
a chemical examination of euphorbia hirta linn. 19665978708
[quercetin-3-glucuronide and camphorol-3-glucuronide, main flavonoids in euphorbia cyparissias l]. 19665993457
[constituents of euphorbia adenochlora. 1]. 19666010721
[constituents of euphorbia watanabei. 1]. 19666010722
preliminary phytochemical and pharmacological studies on euphorbia dracunculoides, lam. 19676036055
chemical study of the latex, stems, bracts, and flowers of "christmas flower" (euphorbia pulcherrima). i. 19676049711
[acute conjunctivitis and keratitis due to the sap of euphorbia marginata]. 19676078334
alteration in biogenic amine levels in the snail lymnaea acuminata by the latex of euphorbia royleana.the latex of euphorbia royleana which has high molluscicidal and anti-cholinesterase activity against lymnaea acuminata reduced the levels of 5-hydroxytryptamine (5ht) and dopamine (da) in the nervous tissue of l. acuminata. there was, however, no significant change in the level of 5-hydroxyindole acetic acid (5hiaa). the changes were found to be dependent on concentration of the latex extract. similar changes were produced by both water and organic solvent extracts of the latex. the latex of e. ...19846204425
[antineoplastic effect of euphorbia fischeriana steud on mice with implanted tumor]. 19846233041
combined effect of the extracts from croton tiglium, euphorbia lathyris or euphorbia tirucalli and n-butyrate on epstein-barr virus expression in human lymphoblastoid p3hr-1 and raji cells.the combined usage of n-butyrate and 12-o-tetradecanoylphorbol-13-acetate (tpa) or the oily extracts from croton tiglium, euphorbia lathyris or euphorbia tirucalli exerted a marked effect on induction of epstein-barr virus (ebv)-associated early (ea) and viral capsid (vca) antigens in ebv genome-carrying human lymphoblastoid cell lines. in producer p3hr-1 cells, the enhancing effect of the 2 components was additive both for ea and vca, while in non-producer raji cells, a synergistic increase of ...19816266651
essential sulfhydryl groups in diamine oxidase from euphorbia characias latex.diamine oxidase from euphorbia characias latex contains two sulfhydryl groups per mole of dimeric enzyme. the sulfhydryl groups are unreactive in the native enzyme but can be readily titrated by 4,4'-dithiodipyridine after protein denaturation, or anaerobically in the presence of the amine substrate. in the presence of both substrates (diamine and oxygen) they react sluggishly. the sulfhydryl groups show different reactivity toward various reagents, but in every case their modification inhibits ...19836401986
tumor promoting and skin irritant diterpene esters of euphorbia virgata latex.the mouse ear irritant latex of e. virgata, has been found to contain various skin irritant and non-irritant esters of the diterpene ingenol. in cocarcinogenic assay on dorsal back skin of nmri mice, acetone extract of this latex produces squamous cell papilloma. using a combination of biologic and chemical separation techniques one of the initiator-promotor for skin carcinogenesis has been identified as 3-0-2 methyl-decanoyl ingenol.19816458773
effects of euphorbia prostrata and fumaria parviflora in normoglycaemic and alloxan-treated hyperglycaemic rabbits. 19846473545
macrocyclic lathyrane type diterpene esters (jolkinols) from callus cultures and roots of euphorbia lathyris. 19846484031
correlation of the anticholinesterase and molluscicidal activity of the latex of euphorbia royleana on the snail lymnaea acuminata. 19846491683
function of the lower intestine and osmoregulation in the ostrich: preliminary anatomical and physiological observations.the gross anatomy of the lower intestine of the african ostrich (struthio camelus) was investigated in four adult birds shot in the wild. the presence of 80 cm long paired caeca, and approximately 10 m of colon between ileum and the cloaca was confirmed. urine, but not faeces, was found in the coprodeum. retrograde flow into the colon was not observed. samples of contents from the lower intestine were secured from these birds and the water content, osmolality and concentrations in the supernatan ...19846514998
active principles of the euphorbiaceae. vii. milliamines h and i, peptide esters of 20-deoxy-5 epsilon-hydroxyphorbol from euphorbia milii. 19846517976
pichia euphorbiae sp. nov., a new haploid heterothallic yeast species.representatives of an undescribed, haploid, heterothallic yeast species, pichia euphorbiae, have been recovered from insect-infested specimens of euphorbia ingens. the new species is considered to be another representative of the apparently related group of heterothallic species, comprising pichia rhodanensis, pichia wickerhamii, pichia veronae, pichia amylophila, pichia mississippiensis and pichia meyerae. while no mating response was observed in interspecific mixtures of the mating types of th ...19836614897
isolation and partial characterization of a lectin from euphorbia heterophylla seeds.an n-acetylgalactosamine-specific lectin was isolated from euphorbia heterophylla seeds by affinity chromatography on cross-linked arabinogalactan. it is a dimeric protein of two identical subunits of mr 32 000, and differs structurally from all previously known euphorbiaceae lectins. its distribution over the seed is typical in that it is merely confined to the primary axes.19836626171
the dermatitis-producing constituents of euphorbia hermentiana latex.five ingenane derivatives, 3-o-n-(deca-2,4,6-trienoyl)-16-o-[(z)-2-methyl-2-butenoyl]-16-hydroxyingenol (1), 3-o-[(z)-2-methyl-2-butenoyl]-5,16,20-o-triacetyl-16-hydroxyingenol (2), 3-o-[(z)-2-methyl-2-butenoyl]-16,20-o-diacetyl-16-hydroxyingenol (3), 3-o-[(z)-2-methyl-2-butenoyl]-20-o-acetylingenol (4), and 3-o-[(z)-2-methyl-2-butenoyl]-16-o-acetyl-20-deoxy-16-hydroxyingenol (5) were isolated with a new procedure that uses droplet counter-current chromatography, from a dermatitis-producing frac ...19836655474
purification and properties of two lectins from the latex of the euphorbiaceous plants hura crepitans l. (sand-box tree) and euphorbia characias l. (mediterranean spurge).1. from the latex of two members of the plant family euphorbiaceae, hura crepitans l. (sand-box tree) and euphorbia characias l. (mediterranean spurge), two lectins were purified by affinity chromatography on acid-treated sepharose 6b followed by elution with d-galactose. 2. the lectin from e. characias is a single molecular species with mr 80 000, made up of two identical subunits with mr 40 000, and is a glycoprotein containing 11% carbohydrate. 3. the lectin from h. creptians appears as a mix ...19836661180
anti-inflammatory activity of euphorbia acaulis roxb.from various extracts of euphorbia acaulis , the n-hexane fraction showed marked anti-inflammatory activity in carrageenan induced oedema in rats and mice as compared to phenylbutazone and was equipotent in adrenal- ectomised rats. in chronic models of formaldehyde and adjuvant arthritis, its anti-arthritic activity was found to be superior to that of phenylbutazone. it had a diuretic effect but did not show any analgesic or antipyretic activity.19846727400
use of potato disc and brine shrimp bioassays to detect activity and isolate piceatannol as the antileukemic principle from the seeds of euphorbia lagascae.etoh extracts of the seeds of euphorbia lagascae inhibited crown gall tumors on potato discs, were active against 3ps (in vivo) and 9ps (in vitro) mouse leukemia, and were toxic to brine shrimp. using the potato disc and brine shrimp bioassays to monitor fractionation, piceatannol (3,4,3',5'- tetrahydroxystilbene ) was isolated as the 3ps active principle. aesculetin (6,7-dihydroxycoumarin) was isolated in large quantity, was weakly cytotoxic in 9kb , but was inactive in the other bioassay syste ...19846736971
tumor promoting activity of euphorbia striatella (boiss) and skin irritant activity of some euphorbia species.out of seven plants selected due to their use in folk medicine, five possessing ingenol as diterpene parent, exhibited mild skin irritancy where as e. striatella latex was highly skin irritant and produced papilloma, in initiation-promotion experiment on mouse back skin. this tumor promoting activity has been demonstrated due to the presence of ingenol-3-o-decanoate.19846738758
on the active principles of the spurge family (euphorbiaceae). v. extremely skin-irritant and moderately tumor-promoting diterpene esters from euphorbia resinifera berg.the irritant and tumor-promoting principles were isolated from the latex of euphorbia resinifera berg. and from the resin derived from latex (euphorbium), which is commercially available as a drug. the irritant euphorbia factors rl 5 (mixture), rl 6, rl 7, rl 8, and rl 10 were identified as tigliane-type 12-deoxyphorbol esters each bearing, in the 13 position, either long-chain, partially methyl-substituted acyl residues (10-16 carbon atoms) or short-chain acyl residues (4 or 5 carbon atoms) or ...19846746723
purification and properties of diamine oxidase from euphorbia latex.a diamine oxidase has been purified to homogeneity from the latex of an herbaceous shrub, euphorbia characias. this enzyme has a relative molecular mass of 144,000 and is composed of two identical subunits. it contain two cu(ii) and two carbonyl-like groups per dimer. the purified enzyme is pink and shows a broad absorption in the visible region centered at 480 nm, which is modified by the addition of phenylhydrazine or semicarbazide. the electron paramagnetic resonance spectrum is typical of co ...19826814913
a neglected mayan galactagogue - ixbut (euphorbia lancifolia).a herbal tea, made of leaves of ixbut (euphorbia lancifolia schlecht.), has been used for several centuries by postpartum mayan women in guatemala to stimulate and increase the flow of mother's milk. ixbut, when mixed with cattle fodder, is reputed to have increased milk yields in cows. to date, the active principle of ixbut has never been isolated. however, this medicinal herb, a natural galactagogue of central american origin, would appear to be worthy of further chemical and pharmacological s ...19827033669
on the active principles of the spurge family (euphorbiaceae). iv. skin irritant and tumor promoting diterpene esters from euphorbia ingens e.mey.the irritant and tumor-promoting principles of the latex of euphorbia ingens e. mey have been isolated together with several nonirritant compounds. the euphorbia factors i1, i5, and i6 are esters of ingenane-type poly-functional diterpene alcohols. euphorbia factor i1 is characterized as the 3-hexadecanoate of the polyfunctional parent alcohol ingenol and euphorbia factor i6 as the 3-deca-2.4.6-trienoic acid ester of ingenol. euphorbia factor i5 is the 16-angelate-3-deca-2.4.6-trienoate of 16-hy ...19827118989
[constituents of euphorbiaceae, 7. 20-deoxyingenol monoesters and ingenol diesters from euphorbia biglandulosa desf]. 19827159190
skin irritant ingenol esters from euphorbia esula. 19827163415
effects of a 4-deoxyphorbol triester from the latex sap of euphorbia biglandulosa desf. on isolated spinach chloroplasts. 19817245219
irritant contact dermatitis from an ornamental euphorbia.an ornamental succulent plant sold in many plant stores in the chicago area has been identified as euphorbia hermentiana lem. open and closed patch testing using undiluted latex from this species was performed on five caucasian volunteers. open testing on flexor forearms resulted in irritant follicular dermatitis, while closed testing to the flexor surfaces of both upper arms in each subject produced bullae and vesiculation with residual desquamation and hyperpigmentation. dermatological signs p ...19817249622
euphorbia peplus latex keratoconjunctivitis. 19817258972
dry column chromatographic procedure for rapid concentration of biological activity in natural products fractionation.a dry column chromatographic procedure is described. it allows for the rapid concentration of biologically active materials in natural products fractionation. the potential value of the technique is described, utilizing as an example the separation of an anticancer active fraction obtained from euphorbia cyparissias.19817264904
testing for tumor promoters in euphorbia lathyris: analysis of possible health hazards. 19817337864
screening of euphorbia from azarbaijan for skin irritant activity and for diterpenes. 19807367489
skin irritants of the sun spurge (euphorbia helioscopia l.).euphorbia helioscopia is a common herbaceous week found in the british isles and parts of europe. it has been responsible for poisoning of livestock resulting in severe inflammation particularly of mucous membranes and the eyes. four esters of 12-deoxyphorbol were isolated from the fresh aerial parts of the plant and their irritant doses 50% (i.d.50) ascertained using female l.a.c.a. mice, 12-deoxyphorbol-13-phenylacetate-20-acetate was found to be the major component of the toxic fraction and o ...19807389328
inhibition of mitochondrial oxidative phosporylation by 4-deoxyphorbol triester, a poisonous constituent of the latex sap of euphorbia biglandulosa desf. 19807394805
toxicity of fresh poinsettia (euphorbia pulcherrima) to sprague-dawley rats.fresh leaves and bracts of poinsettia (euphorbia pulcherrima) were fed to 46 sprague-dawley rats. the animals were observed for 1 week for changes in weight or behavior. the animals were then sacrificed in ether and examined for changes in thyroid and adrenal weights. one group was also examined for damage to the duodenum, jejunum, and ileum. no lesions or other signs of intestinal damage were observed. none of the groups showed any change in behavior or any significant change in body weight or ...19807398206
constituents of egyptian euphorbiaceae. ix. irritant and cytotoxic ingenane esters from euphorbia paralias l.the irritant and cytotoxic constituents of the latex of euphorbia paralias l. were separated from the hydrocarbon fraction by means of solvent partition. 3 new ingenane esters were identified from the toxic ether fraction. the major compound was 3-angelyl-20-deoxyingenol and the 2 minor compounds were 3-hexanoyl-20-deoxyingenol and 3-angelyl-ingenol. these compounds were of a similar potency to podophyllin in the inhibition of 3h-thymidine uptake by tlx/5 mouse lymphoma cells. in addition the co ...19807418805
[the effect of the sap of euphorbiaceae on the eye].ocular inflammations caused by the latex of euphorbiaceae manifest themselves as lid swelling, severe conjunctivitis, keratitis and iritis with hypopyon. as therapy, the local application of corticosteroids is recommended. in severely affected cases intravenous injections of sandosten-calcium and solu-dacortin (merck) are indicated. the caustic effect of euphorbia cyparissias is caused by phorbol acid and phorbol acid ester. on the canary islands, the latex of euphorbiaceae is quickly removed by ...19807421015
presence of a tumor-promoting factor in honey.honey samples collected from the saidabad area of azarbaijan province of iran were found to be moderately irritant, and this activity was associated with the presence of tri-acylates of the diterpene ingenol, which are transferred from the nectar of euphorbia seguieriana neck by honey bees to the honey. the acylates of ingenol are known promoters of carcinogenesis.19807429090
traditional medicine in health care.the state of research on plants used in traditional medicine and its development in egypt is indicated by the number of scientific institutions devoted to this problem: universities, the national research centre, the desert institute and the horticulture department of the ministry of agriculture. moreover, the use of certain medicinal plants has been "industrialised', e.g., ammi visnaga, cymbopogon proximus, nigella sativa and aloe vera. other plants are under investigation: urginea maritima, ph ...19807464176
isolation, in vitro culture, ultrastructure study, and characterization by lectin-agglutination tests of phytomonas isolated from tomatoes (lycopersicon esculentum) and cherimoyas (anona cherimolia) in southeastern spain.plants of lycopersicon esculentum (grown in greenhouses) and anona cherimolia cultivated in southeastern spain were examined for the presence of trypanosomatid flagellates. kinetoplastid protozoa were found in the fruits but not in the phloem or other plant tissues. parasites were detected from the onset of fruiting. isolates were detected from the onset of fruiting. isolates were adapted to in vitro culturing in monophase media. the form and the structural organization was studied by scanning a ...19957479649
the glycoinositol-phospholipids of phytomonas.the phytomonas spp. are trypanosomatid parasites of plants. a polar glycolipid fraction of a phytomonas sp., isolated from the plant euphorbia characias and grown in culture, was fractionated into four major glycolipid species (phy 1-4). the glycolipids were analysed by chemical and enzymic modifications, composition and methylation analyses, electrospray mass spectrometry and microsequencing after hno2 deamination and nab3h4 reduction. the water-soluble headgroup of the phy2 glycolipid was also ...19957487886
purification and partial characterization of a lectin from euphorbia neriifolia latex.a lectin was purified from euphorbia neriifolia latex to homogeneity by affinity chromatography on sepharose 4b. the protein appears to be a dimer with approximate m(r) of 60,000 on gel filtration and showing a single band at m(r) 32,000 in sds-page, and contains 12.3% carbohydrate. it agglutinated trypsinized human and rabbit erythrocytes, but not sheep erythrocytes. however, sialidase-treated sheep erythrocytes were agglutinated. the galactose and galactose containing sugars inhibited the heam ...19957492957
four diterpene esters from euphorbia myrsinites.the turkish species euphorbia myrsinites has yielded four new tetracyclic diterpene tetraesters from a cytotoxic acetone extract, in addition to the known cycloartane-type triterpenoids and betulin. the new compounds and their hydrolysis product have been extensively characterized by high field spectroscopic techniques, and were shown to be four new tetraesters of the parent alcohol, myrsinol.19957540394
fractionation and characterization of two forms of peroxidase from oryza sativa.peroxidase (e.c. 1.11.1.7., hydrogen donor oxidoreductase) is widely distributed and has been isolated from many higher plants (1). the wide distribution of the enzyme suggests that it could be of great biological importance. however the role that it plays in metabolism is not clear due to the large number of reactions it catalyzes and the considerable number of isozymic species (2). in tomato plants, evans and aldridge (3) separated out six isoperoxidases and in a later paper evans reported 12 ...19957603969
formation of novel poly(hydroxyalkanoates) from long-chain fatty acids.poly(hydroxyalkanoates) (phas) were isolated from pseudomonas aeruginosa 44t1 cultivated on euphorbia oil and castor oil. with the aid of 2-d proton nmr spectra and proton-detected multiple bond coherence nmr spectra the structures of the phas were determined. in addition to the usual pha constituents (c6-c14 3-hydroxy fatty acids), phas formed from euphorbia oil contained delta 8,9-epoxy-3-hydroxy-5c-tetradecenoate, and probably delta 6,7-epoxy-3-hydroxydodecanoate and delta 4,5-epoxy-3-hydroxy ...19957606658
characterisation of ingenol: an inflammatory diterpene from some nigerian euphorbia and elaeophorbia species.inflammatory latices of euphorbia deightonii, euphorbia desmondi, elaeophorbia drupifera and elaeophorbia grandiflora were found to contain ingenol as the parent alcohol of the diterpene esters. the chemotaxonomic significance of the occurrence of ingenol in the genus elaeophorbia is discussed.19947625305
[a review of the processing of euphorbia kansui liou]. 19957626206
[chemical constituents of euphorbia nematocypha hand.-mazz].four compounds were isolated from the roots of euphorbia nematocypha. three of them were identified as a'-neogammacer-22(29)-en-3 beta-ol (18 beta.21 alpha) (ii), jolkinolide e (iii) and beta-sitoesterol (iv). among them, ii was obtained from the genus euphorbia and iii from this plant for the first time.19957646781
the ethnopharmacology of madeira and porto santo islands, a review.the ethnopharmacology of madeira and porto santo islands is extremely interesting because of the cultural and biogeographic features of this region, which make it a centre of medicinal plant diversity (richness of endemic flora, geographical isolation in the atlantic sea, crosscultural influences, and past abundance of local healers). the medicinal flora of madeira is composed of 259 species. some noteworthy medicinal taxa, endemic or locally relevant, are: acanthus mollis, aeonium glandulosum, ...19957650952
a soap technique for cell separation to study the seed coat of sesbania punicea.a technique is described for separating plant cells used for morphological studies. the plant material is placed in a concentrated solution of olive oil castile soap for 1-2 days or more. the material is then thoroughly washed and placed between two glass slides. the upper glass slide is lifted from the lower one, then gently pressed down several times. through this procedure malpighian cells of the seed coat of sesbania punicea, mesophyll cells of euphorbia peplus and of trifolium pratense and ...19937687883
tumour promoter activity in malaysian euphorbiaceae.herbal medication has been practised by the rural malaysian malays for a long time. however, the long-term side-effects have never been studied. in the present study, 48 species of euphorbiaceae were screened for tumour-promoter activity by means of an in vitro assay using a human lymphoblastoid cell line harbouring the epstein-barr virus (ebv) genome. twenty-seven per cent (13 out of 48) of the species tested were found to be positive, and in four species, namely breynia coronata hk.f, codiaeum ...19957710943
cryptic dysfunction of cellular immunity in asymptomatic human immunodeficiency virus (hiv) carriers and its actualization by an environmental immunosuppressive factor.peripheral blood lymphocytes from 4 asymptomatic hiv-1 carriers with normally retained ebv-specific cytotoxic t-cell activity were exposed to ebv and incubated with 0.2 ng/ml 4-deoxyphorbol ester, an immunosuppressive substance derived from an african plant euphorbia tirucalli. the regression of ebv-induced b-cell transformation by ebv-specific cytotoxic t-cells was significantly impaired in the presence of a small amount of 4-deoxyphorbol ester, but not so in 5 hiv-1-seronegative healthy counte ...19947772730
new myrsinol-related polyfunctional pentacyclic diterpene esters from roots of euphorbia prolifera.five euphorbia substances, spr1-spr5, were isolated from the roots of euphorbia prolifera. they were found to have similar structures but were inactive in a mouse ear inflammation assay. by nmr analysis and after single-crystal x-ray crystallography the structure of spr5 was established as a hexaester (tetraacetate-benzoate-propionate) of a hitherto unknown polyfunctional pentacyclic diterpene parent alcohol, structurally related to myrsinol. as judged from its nmr spectra, spr4 is an analogue o ...19957775985
perspectives of using euphorbia splendens as a molluscicide in schistosomiasis control programs.a total of 1,426 species of plants had been tested in order to find out a vegetal-derived molluscicide against the vectors of schistosoma mansoni. euphorbia splendens is one of the most promising molluscicides. in this article we briefly present the main aspects that have to be considered to use this plant as a molluscicide, which include some agricultural aspects and operational methods for application. this can be done by the extraction of the active principles (millaminas) present in the late ...19947777901
biologically active compounds from the euphorbiaceae; 2. two triterpenoids of euphorbia cyparissias. 19947809217
acute kerato-uveitis associated with topical self-administration of the sap of the petty spurge (euphorbia peplus) 19947867832
euphorbia lathyris latex keratoconjunctivitis. 19947867833
aerobic and anaerobic glucose metabolism of phytomonas sp. isolated from euphorbia characias.metabolic studies on phytomonas sp. isolated from the lactiferous tubes of the latex-bearing spurge euphorbia characias indicate that glucose is the preferred energy and carbon substrate during logarithmic growth. in stationary phase cells glucose consumption was dramatically reduced. glucose consumption and end-product formation were measured on logarithmically growing cells, both under aerobic (air and 95% o2/5% co2) and anaerobic (95% n2/5% co2 and 100% n2) conditions. the rate of glucose con ...19947870136
functional connection between intracellular and extracellular secretion in species of euphorbia genus.in species of the euphorbia genus the intracellular latex-secretion and the extracellular nectar-secretion are anatomically connected. the functional connection of the secretional systems was proved to be probable by tlc and gc-msd. the chemical composition of euphorbia latex and honey was examined with these analytical methods. in our research, the comparative chemical analysis of the latex and the honey of two euphorbia species (euphorbia cyparissias l., euphorbia seguieriana necker.) was disc ...19937871930
[identification of euphorbia humifusa wind, and e. maculata raf. from its confused species e. thymifolia l]. 19947945877
[clinical analysis of 72 epileptic patients treated with alkaline extract of euphorbia fisheriana].the effect of 72 epileptic patients treated with alkaline extract of euphorbia fisheriana (ef) was reported. 22 of them with intractable epilepsy were compared with the treatment of both single-blind and placebo. the results showed that the total effective rate with ef was 78%, its marked effective rate was 42% and the effective rate 36%. the epileptic patients reduced their frequency of seizures significantly (p < 0.05), while the effective rate of 22 epileptic patients with single-blind treatm ...19947950213
tannins and related polyphenols of euphorbiaceous plants. xi. three new hydrolyzable tannins and a polyphenol glucoside from euphorbia humifusa.three new hydrolyzable tannins, euphormisins m1, m2, and m3, were isolated from euphorbia humifusa willd., and respectively characterized as 1,3,6-tri-o-galloyl-4-o- brevifolincarboxyl-beta-d-glucose (19), an oxidative metabolite (23) of geraniin, and 1,3,6-tri-o-galloyl-alpha-d-glucose (18), by spectroscopic and chemical methods. a new ellagic acid glucoside (16) and fifteen known tannins, including geraniin (8) and four dimers [euphorbins a (13), b (14), excoecarianin (15) and eumaculin a (12) ...19947954930
lipases of the euphorbiaceae family: purification of a lipase from euphorbia characias latex and structure-function relationships with the b chain of ricin.a lipase from the latex of euphorbia characias was purified using a method involving extraction with apolar solvent and adsorption chromatography on silica gel. the lipase (specific activity, 1500 international units/mg of protein) was eluted from silica gel complexes with a lipid. the main protein fraction, which had a molecular mass of 38 kda, was inactive when dissociated from the lipid fraction. when the lipid and protein fractions were reassociated, 72% of the lipolytic activity was recover ...19947972058
influence of some traditional medicinal plants of senegal on prostaglandin biosynthesis.aqueous extracts of combretum micranthum g. don, euphorbia hirta l., guiera senegalensis lam. and melaleuca leucadendron l. were investigated for their influence on prostaglandin biosynthesis (pg i2, pg e2, pg d2). only the extract of euphorbia hirta strongly reduced the release of prostaglandins i2, e2, and d2. additionally euphorbia hirta extracts exerted an inhibitory effect on platelet aggregation and depressed the formation of carrageenin induced rat paw oedema. the chemical nature of the a ...19947980813
[determination of esculetin in semen euphorbiae lathyridis l. by tlcs and comparison on the quality in different areas].a tlc-densitometric method for the determination of oesculetin in semen euphorbia lathyridis (euphorbiae lathyrdis) was established, and esculetin content in semen euphorbia lathyridis from three different producing areas (zhengzhou, chengdu and chongqing) was determined. the method is accurate, sensitive and simple. the recovery is 98.63% and the coefficient of variation is 1.59% (n = 5). the esculetin average contents in the three samples are 0.3013%, 0.2046% and 0.2094% respectively.19938011091
screening of epstein-barr virus early antigen expression inducers from chinese medicinal herbs and plants.ether extracts of 1693 chinese medicinal herbs and plants from 268 families were studied for the induction of epstein-barr viral (ebv) early antigen (ea) expression in the raji cell line. fifty-two from 18 families were found to have inducing activity. twenty-five and seven of them were from euphorbiaceae and thymelaeaeeae, respectively. some of them, such as croton tiglium, euphorbia kansui, daphne genkwa, wikstroemia chamaedaphne, wikstroemia indica, prunus mandshurica koehne and achyranthes b ...19948024719
molecular phylogeny of families related to celastrales based on rbcl 5' flanking sequences.the region between the rbcl and atpb chloroplast genes and the first 53 codons of the rbcl gene have been sequenced for 19 species of angiosperms. nine of these belong to the four largest families within the order celastrales sensu cronquist (i.e., aquifoliaceae s.l., icacinaceae, celastraceae, and hippocrateaceae). both phenetic and cladistic approaches were used to test the monophyly of the order and to specify its relationships with euphorbiaceae, rhamnaceae, rosaceae, and theaceaea. based up ...19948025727
resiniferatoxin and piperine: capsaicin-like stimulators of oxygen uptake in the perfused rat hindlimb.the naturally occurring capsaicin-like molecules, resiniferatoxin (rtx, euphorbia spp.) and piperine (piper nigrum), each stimulated oxygen uptake (vo2) in association with increased vascular resistance in a concentration-dependent manner when infused into the perfused rat hindlimb. 5 microm glyceryl trinitrate (gtn, a nitrovasodilator) significantly blocked the oxygen and pressure responses to both rtx and piperine, indicating a close relationship between changes in vo2 and the vasoconstriction ...19948035653
constituents of euphorbiaceae 12. comm. (1). isolation and structure elucidation of four new cerebrosides from euphorbia biglandulosa desf.four new cerebrosides 4-6 were isolated from the latex of euphorbia biglandulosa desf. and their structures determined. normal and reverse-phase flash chromatography was effective for the isolation of the cerebrosides, and fab-ms spectrometry, 1h-nmr, 13c-nmr, dqf-cosy and hmqc experiments and chemical reactions were useful in elucidating their structure. ei-ms of the dimethyl disulfide derivatives of the long chain bases and glucosphingoside-heptaacetates was decisive for the determination of t ...19948043167
african burkitt's lymphoma: a plant, euphorbia tirucalli, reduces epstein-barr virus-specific cellular immunity.endemicity of burkitt's lymphoma (bl) coincides with profusion of a plant euphorbia tirucalli in tropical africa. e. tirucalli contains 4-deoxyphorbol ester that enhances epstein-barr virus (ebv) infection of b lymphocytes. in this study, we found that 4-deoxyphorbol ester reduced ebv-specific cytotoxic t-cell function. furthermore, the b lymphocytes dually exposed to ebv and 4-deoxyphorbol ester were resistant to ebv-specific t cell cytotoxicity, through down-regulation of latent membrane prote ...19948074496
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