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isolation of a lectin and a galactoxyloglucan from mucuna sloanei seeds.a lectin and a galactoxyloglucan were characterized from mucuna sloanei seed cotyledons. the galactoxyloglucan, isolated by water extraction and ethanol precipitation, had glc:xyl:gal proportions in a molar ratio of 1.8:1.7:1.0 and a molar mass (m(w)) of 1.6x10(6)g mol(-1). the lectin (sloanin), isolated from the same seed by affinity chromatography on cross-linked adenanthera pavonina galactomannan, gave two protein bands by sds-page (36 and 34 kda) and one peak by gel filtration (63.6 kda). it ...200919783018
antiviral and antioxidant activities of sulfated galactomannans from plants of caatinga biome.dengue represents a serious social and economic public health problem; then trying to contribute to improve its control, the objective of this research was to develop phytoterapics for dengue treatment using natural resources from caatinga biome. galactomannans isolated from adenanthera pavonina l., caesalpinia ferrea mart., and dimorphandra gardneriana tull were chemically sulfated in order to evaluate the antioxidant, and antiviral activities and the role in the inhibition of virus denv-2 in v ...201526257815
effects of proteinase inhibitor from adenanthera pavonina seeds on short- and long term larval development of aedes aegypti.currently, one of the major global public health concerns is related to the transmission of dengue/yellow fever virus by the vector aedes aegypti. the most abundant digestive enzymes in ae. aegypti midgut larvae are trypsin and chymotrypsin. since protease inhibitors have the capacity to bind to and inhibit the action of insect digestive proteinases, we investigated the short- and long-term effects of adenanthera pavonina seed proteinase inhibitor (apti) on ae. aegypti larvae, as well as a possi ...201525796215
anti-hyperglycaemic and lipid lowering potential of adenanthera pavonina linn. in streptozotocin induced diabetic rats.in india, adenanthera pavonina is traditionally used in the treatment of diabetes mellitus and lipid disorders. in the present study, the antihyperglycaemic and lipid lowering effect of adenanthera pavonina seed aqueous extract (apsae) was evaluated using streptozotocin induced diabetes in rats. streptozotocin was given at the dose of 55 mg/kg, i.p. after induction of diabetes, apsae was administered for 30 days p. o. and simultaneously different biochemical parameters like plasma glucose, hba1c ...201222924034
[investigation on emission properties of biogenic vocs of landscape plants in shenzhen].isoprene and monoterpene emissions were characterized using flow and enclosure sampling method and gc-ms in usa for 158 species of plants growing in shenzhen, china. this survey was designed to include all of the dominant plants within the shenzhen region as well as unique plants such as cycads. these are the first measurements in a subtropical asian metropolis. substantial isoprene emissions were observed from thirty-one species, including caryota mitis, adenanthera pavonina var. microsperma, m ...201122468517
evaluation of phytochemical composition and antioxidant capacity of a decoction containing adenanthera pavonina l. and thespesia populnea l.a decoction prepared with barks of adenanthera pavonina and thespesia populnea is a herbal formulation which has been prescribed in sri lanka in the treatment of cancer patients for many years. this study was designed to investigate its phytochemical and antioxidant properties.201121969789
physiological and biochemical changes during the loss of desiccation tolerance in germinating adenanthera pavonina l. seeds.we investigated the loss of desiccation tolerance (dt) in adenanthera pavonina seeds during germination. seeds were subjected to imbibition for 0, 24, 36, 48, 60 and 81 h, then dried to their initial moisture content (13%), rehydrated and evaluated for survival (resumption of growth and development of normal seedlings) and membrane system integrity (electrolyte leakage). embryonic axes of seeds subjected only to imbibition during the same early time periods were used to investigate the electroph ...201526628022
evaluation of anticancer properties of a decoction containing adenanthera pavonina l. and thespesia populnea l.a decoction composed of adenanthera pavonina l. and thespesia populnea l. is currently being used in the treatment of cancer patients.201626896952
in-vitro alpha amylase inhibitory activity of the leaf extracts of adenanthera pavonina.diabetes has caused a major burden to the health sector in the developing countries and has shown an increasing trend among the urban population. it is estimated that most patients are with type ii diabetes which could be easily treated with dietary changes, exercise, and medication. sri lanka carries a long history ayurvedic medicine where it uses the plant for treating many diseases. therefore it is important to screen medicinal plants scientifically so they could be used safely and effectivel ...201627846876
triterpenoids of adenanthera pavonina bark. 1976948518
stigmasterol glucoside a constituent of adenanthera pavonina seed and leaf. 19734705793
dormancy as exaptation to protect mimetic seeds against deterioration before dispersal.mimetic seeds simulate the appearance of fleshy fruits and arilled seeds without producing nutritive tissues as a reward for seed dispersers. in this strategy of seed dispersal, seeds may remain attached to the mother plant for long periods after maturity, increasing their availability to naïve seed dispersers. the hypothesis that seed coat impermeability in many tropical fabaceae with mimetic seeds serves as an exaptation to protect the seeds from deterioration and rotting while awaiting disper ...201020354070
characterization and antiherpetic activity of native and chemically sulfated polysaccharide from adenanthera pavonina.the herpes simplex virus (hsv) is a widespread human pathogen and for many reasons the development of anti-herpetic drugs from natural products has been encouraged. adenanthera pavonina (ap) is a medicinal plant widely used in brazil, among other uses. herein, a native ap seed polysaccharide (plsap) and its chemically sulfated derivate (splsap) were studied by fourier transform ir spectra (ft-ir), gel permeation chromatography (gpc) for molar mass determination and their intrinsic viscosity [η]. ...201526238681
antiviral activity of sulfated polysaccharide of adenanthera pavonina against poliovirus in hep-2 cells.adenanthera pavonina, popularly known as red-bead tree, carolina, pigeon's eye, and dragon's eye, is a plant traditionally used in brazil for the treatment of several diseases. the present study aimed at evaluating the activity of sulfated polysaccharide from the adenanthera pavonina (splsap) seeds against poliovirus type 1 (pv-1) in hep-2 cell cultures. the splsap presented a cytotoxic concentration (cc50) of 500 μg/ml in hep-2 cell cultures, evaluated by the dimethylthiazolyl-diphenyltetrazoli ...201425221609
antimicrobial peptides from adenanthera pavonina l. seeds: characterization and antifungal activity.in this study, the antifungal activity of peptides extracted from adenanthera pavonina seeds was assessed. peptides were extracted and fractionated by deae-sepharose chromatography. the non-retained d1 fraction efficiently inhibited the growth of the pathogenic fungi. this fraction was later further fractionated by reversed-phase chromatography, resulting in 23 sub-fractions. all separation processes were monitored by tricine-sds-page. fractions h11 and h22 strongly inhibited the growth of sacch ...201222486647
anti-quorum sensing potential of adenanthera pavonina.quorum sensing (qs) in pseudomonas aeruginosa plays a key role in virulence factor production, biofilm formation and antimicrobial resistance. because of emerging antimicrobial resistance in p. aeruginosa, there is a need to find an alternate nonantibiotic agent for the control of infections caused by this organism.201525598643
[adenanthera pavonina, composition of the fat and mass spectrometric analysis of the sterolglucosides]. 20051197419
antibacterial activity of three medicinal thai plants against campylobacter jejuni and other foodborne pathogens.leaves of adenanthera pavonina, moringa oleifera and annona squamosa are used in traditional thai medicine to treat dysentery and other diseases. this study investigated the antibacterial activity of these plants against six species of foodborne pathogen. methods and solvents employed to extract active constituents were optimised using the disc diffusion assay. phytochemical analysis of the optimised extracts was performed by thin layer chromatography (tlc). minimum inhibitory concentrations (mi ...201121878033
emulsions of oil from adenanthera pavonina l. seeds and their protective effect.in our previous study, we developed very stable formulations of submicron oil-in-water emulsions from adenanthera pavonina l. (family leguminosae, subfamily mimosoideae) seed oil, stabilised with soybean lecithin (spc). continuing our research, we introduced an additional co-emulsifier, tween 80, to those formulations in order to decrease the size of the emulsion particles and improve their stability. formulations with a mean particle size ranging from 43.6 to 306.5 nm and a negative surface cha ...200616874455
anti-inflammatory studies on adenanthera pavonina seed extract.a methanol extract of the seeds of adenanthera pavonina was evaluated for pharmacological effects in animal models. the extract (50-200 mg/kg) produced statistically significant (p < 0.05) inhibition of the carrageenan-induced paw oedema in the rat, as well as the acetic-acid-induced vascular permeability in mice. at doses of 100 and 200 mg/kg, pleurisy induced with carrageenan was also inhibited. the extract (50-200 mg/kg) exhibited a dose-dependent and significant (p < 0.05) analgesic activity ...200415265320
a kunitz-type inhibitor of coleopteran proteases, isolated from adenanthera pavonina l. seeds and its effect on callosobruchus maculatus.the cowpea weevil callosobruchus maculatus is one of the major pests of vigna unguiculata cowpea. digestion in the cowpea weevil is facilitated by high levels of cysteine and aspartic acid proteinases. plants synthesize a variety of molecules, including proteinaceous proteinase inhibitors, to defend themselves against attack by insects. in this work, a trypsin inhibitor (apti) isolated from adenanthera pavonina seeds showed activity against papain. the inhibition of papain by apti was of the non ...200415113152
isolation and partial characterization of a lectin from artocarpus incisa l. seeds.a lectin was isolated from the saline extract of artocarpus incisa seed by affinity chromatography on cross-linked adenanthera pavonina galactomannan in 0.15 m nacl. the lectin was also retained in a d-gal-agarose resin and had no requirements for divalent metal cations (ca2+ and mn2+) for activity. the lectin contains 2.1% of carbohydrate and is characterized by high contents of acidic and hydroxylated amino acids. the lectin presented two protein bands in sds-page, with m(r) 15.5 and 12 kda, r ...19989611823
pavonin: a new five-membered lactone from adenanthera pavonina linn. (mimoaceae).a new five-membered lactone named pavonin with an exo-cyclic double bond has been isolated from the methanol soluble part of adenanthera pavonina linn. belonging to the family mimoaceae. the structure of pavonin has been established with the aid of spectroscopic techniques including decoupling and hmbc experiments.200515700643
expression of chitinase in adenanthera pavonina seedlings.chitinases (ec 3.2.1.14) are hydrolytic enzymes found in different organisms. in plants, they have been described in different tissues and organs, including seeds. this study was triggered by the isolation of a 30-kda thermostable chitinase from adenanthera pavonina l. seeds. the enzyme was submitted to n-terminal amino acid sequencing, and the analysis revealed a high degree of homology with class iii chitinases. bidimensional electrophoresis of the 30-kda band showed the presence of three isof ...200718251927
the oil of adenanthera pavonina l. seeds and its emulsions.the oil of adenanthera pavonina l. seeds was analysed by chromatographic and instrumental means. the oil was found to be rich in neutral lipids (86.2%), and low in polar lipids (13.8%). the neutral lipids consisted mainly of triacylglycerols (64.2%). unsaturated fatty acids were found as high as 71%, while the percentage of saturated fatty acids was only 29%. gc and gc/ms analyses revealed linoleic, oleic and lignocerotic acid to be predominant among all fatty acids in the a. pavonina oil, where ...200918998394
adenanthera pavonina trypsin inhibitor retard growth of anagasta kuehniella (lepidoptera: pyralidae).anagasta kuehniella is a polyphagous pest that feeds on a wide variety of stored products. the possible roles suggested for seed proteinase inhibitors include the function as a part of the plant defensive system against pest via inhibition of their proteolytic enzymes. in this study, a trypsin inhibitor (apti) was purified from adenanthera pavonina seed and was tested for insect growth regulatory effect. the chronic ingestion of apti did result in a significant reduction in larval survival and w ...201020235154
structural and mechanistic insights into a novel non-competitive kunitz trypsin inhibitor from adenanthera pavonina l. seeds with double activity toward serine- and cysteine-proteinases.kunitz proteinase inhibitors are widely distributed in legume seeds, and some of them have the ability to inhibit two different classes of enzymes. in this report, novel insights into three-dimensional structure and action mechanism of apkti, an adenanthera pavonina kunitz trypsin inhibitor, were provided to shed some light on an unconventional non-competitive activity against trypsin and papain. firstly, apkti was purified by two tandem-size molecular exclusion chromatography high resolutions, ...201020816329
extract of adenanthera pavonina l. seed reduces development of diabetic nephropathy in streptozotocin-induced diabetic rats.the aim of the present study was to investigate the renal protective effect of adenanthera pavonina (a. pavonina) seed aqueous extract (apsae), in streptozotocin (stz)-induced diabetic rats.201225050253
a new flavonol glycoside and biological activities of adenanthera pavonina l. leaves.adenanthera pavonina is a plant belonging to family fabaceae. the 95% ethanol extract (etoh) of the dried powdered leaves of the plant and successive extracts with solvents of increasing polarities were prepared. fractionation of the successive aqueous etoh extract on polyamide column and purification of the isolated compounds on sephadex lh20 led to the isolation of a new methoxy flavonol glycoside named as quercetin 3-o-α-dirhamnopyranosyl-(1‴ → 2″,1″″ → 6″)-β-glucopyranoside-4'-methoxy (1), a ...201424289202
short and long-term antinutritional effect of the trypsin inhibitor apti for biological control of sugarcane borer.plant-derived trypsin inhibitors have been shown to have potent anti-insect effects and are a promising alternative for the biological control of pests. in this work, we tested the anti-insect activity of adenanthera pavonina trypsin inhibitor (apti) against diatraea saccharalis larvae, a major insect pest in sugarcane. the addition of 0.1% apti in short-term assays resulted in 87% and 63% decreased trypsin and chymotrypsin activities respectively. apti was not digested after 60h incubation with ...201424355140
cytoprotective and anti-inflammatory effects of kernel extract from adenanthera pavonina on lipopolysaccharide-stimulated rat peritoneal macrophages.to investigate mechanism of anti-inflammatory activity of adenanthera pavonina (a. pavonina) extracts.201525902024
evaluation of antinociceptive activity of ethanol extract of leaves of adenanthera pavonina.adenanthera pavonina is a deciduous tree commonly used in the traditional medicine to treat inflammation and rheumatism. the aim of this study was to evaluate the antinociceptive activity of ethanol extract of leaves of a. pavonina (eeap). eeap was investigated using various nociceptive models induced thermally or chemically in mice including hot plate and tail immersion test, acetic acid-induced writhing, and glutamate- and formalin-induced licking tests at the doses of 50, 100, and 200 mg/kg b ...201526346723
relationship between galactomannan structure and physicochemical properties of films produced thereof.in this work five sources of galactomannans, adenanthera pavonina, cyamopsis tetragonolobus, caesalpinia pulcherrima, ceratonia siliqua and sophora japonica, presenting mannose/galactose ratios of 1.3, 1.7, 2.9, 3.4 and 5.6, respectively, were used to produce galactomannan-based films. these films were characterized in terms of: water vapour, oxygen and carbon dioxide permeabilities (wvp, o 2 p and co 2 p); moisture content, water solubility, contact angle, elongation-at-break (eb), tensile stre ...201526604406
amino acid sequence of the acidic kunitz-type trypsin inhibitor from winged-bean seed [psophocarpus tetragonolobus (l.) dc].the primary sequence of trypsin inhibitor-2 (wbti-2) from psophocarpus tetragonolobus (l.) dc seeds was determined. this inhibitor consists of a single polypeptide chain of 182 amino acids, including four half-cystine residues, and an n-terminal residue of pyroglutamic acid. the sequence of wbti-2 showed 57% identity to the basic trypsin inhibitor (wbti-3) and 50% identity to the chymotrypsin inhibitor (wbci) of winged bean, and 54% identity to the trypsin inhibitor de-3 from erythrina latissima ...19901980416
structure of a sugar chain of a protease inhibitor isolated from barbados pride (caesalpinia pulcherrima sw.) seeds.an asparagine-linked sugar chain of a protease inhibitor from barbados pride (caesalpinia pulcherrima sw.) was liberated by hydrazinolysis. after n-acetylation, the reducing end residue of this carbohydrate unit was coupled with 2-aminopyridine and the pyridylamino (pa-) derivative was purified by gel-filtration and reversed-phase hplc. the structure of the resulting pa-sugar chain was determined mainly by stepwise exoglycosidase digestions and 500 mhz 1h-nmr spectroscopy and proved to be as fol ...19863759923
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