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enterobacterial repetitive intergenic consensus pcr is a useful tool for typing mycobacterium chelonae and mycobacterium abscessus isolates.outbreaks of rapidly growing mycobacterium (rgm) infections are increasingly being reported worldwide. information about genetic relatedness of isolates obtained during outbreaks can provide opportunities for prompt intervention. pulsed-field gel electrophoresis (pfge) is expensive, time consuming, and labor intensive. other than that, mycobacterium abscessus isolates can suffer dna degradation during electrophoresis. polymerase chain reaction (pcr)-based methods are cheaper, faster, and easier ...200616529900
chronic cutaneous disease caused by the rapid growers mycobacterium fortuitum and chelonae. 200616536829
[erythematous nodule on the back of the hand]. 200616595120
soft tissue infection caused by mycobacterium chelonae following a liposculpture and lipofilling procedure.skin and soft tissue infections that usually follow minor traumatic events or surgical procedures are caused by a wide spectrum of bacteria. we describe a soft tissue infection caused by a mycobacterium chelonae in an immunocompetent patient who underwent liposculpture and lipofilling of the gluteal-trochanteric region, emphasizing the importance of clinical suspicion and effective treatment of infection.200516610256
cutaneous leukocytoclastic vasculitis in a child with interleukin-12 receptor beta-1 deficiency.we report a patient with complete interleukin-12 receptor beta-1 deficiency associated with cutaneous leukocytoclastic vasculitis. the patient experienced bacille calmette guérin, mycobacterium chelonae, and salmonella enteritidis infection. vasculitis affecting both small arteries and postcapillary venules due to deposition of immune complexes was probably caused by s. enteritidis and/or m. chelonae infection.200616615980
clinical significance and epidemiology of non-pigmented rapidly growing mycobacteria in a university hospital.to study the clinical significance and epidemiology of non-pigmented rapidly growing mycobacteria (nprgm) during a 13-year period.200716616783
recalcitrant post-lasik mycobacterium chelonae keratitis eradicated after the use of fourth-generation fluoroquinolone.to report a patient with mycobacterium chelonae keratitis after lasik and discuss therapeutic measures.200616647126
[soft-tissue infections due to non-tuberculous mycobacteria following mesotherapy. what is the price of beauty].mesotherapy is widely used in latin america for cosmetic purposes, particularly in obese individuals. we describe the clinical and epidemiological characteristics, microbiological diagnosis, treatment and follow-up of patients from caracas (venezuela) with soft tissue infection caused by non-tuberculous mycobacteria following mesotherapy.200616762255
[inactivation of mycobacteria by disinfectants with a tuberculocidal label].disinfectants available in venezuela, registered as tuberculocidal, and used in clinical and laboratory settings were tested for their mycobactericidal activity.200616762258
in vitro efficacy of cefazolin and povidone-iodine 5% in eradicating microbial organisms adhered to broad scleral buckles. 200616764667
adult cystic fibrosis presenting with recurrent non-tuberculous mycobacterial infections. 200616765765
visual recovery following mycobacterium chelonae endophthalmitis.following uncomplicated cataract surgery, a patient receiving etanercept for psoriatic arthritis developed mycobacterium chelonae endophthalmitis. vitrectomy, capsulectomy, and intraocular lens removal was followed by intravitreal amikacin, topical gatifloxacin, intravenous imipenem, and oral clarithromycin for six months. the patient achieved a final corrected visual acuity of 20/20. etanercept has been implicated in the development of numerous, severe granulomatous infections, though not previ ...200616766402
bilateral mycobacterium chelonae keratitis after laser in situ keratomileusis. 200616767388
cutaneous infection with rapidly-growing mycobacterial infection following heart transplant: a case report and review of the literature.nontuberculous mycobacteria are ubiquitous and infrequently cause disease in humans, most commonly in immunocompromised hosts. one type of nontuberculous mycobacteria is mycobacterium abscessus. this rapidly growing mycobacterium is a soil or water saprophyte. it was previously classified as a subspecies of mycobacterium chelonae; however, current taxonomy now designates it as a separate species. rapidly growing mycobacteria are resistant to the usual antituberculous drugs. this emphasizes the n ...200616797350
mycobacterium chelonae keratitis after laser-assisted subepithelial keratectomy.a 24-year-old man with myopic astigmatism had uncomplicated laser-assisted subepithelial keratectomy (lasek) in october 2004. approximately 4 weeks later, a foreign-body sensation and redness developed in the left eye. a paracentral anterior stromal infiltrate was observed, and gram stain on the day of presentation showed branching filamentous gram-positive rods. cultures subsequently grew mycobacterium chelonae. topical tobramycin 15 mg/ml, azithromycin 2 mg/ml, amikacin 25 mg/ml, and cefazolin ...200616814072
various stages in the life cycle of syrphid flies (eristalis tenax; diptera: syrphidae) as potential mechanical vectors of pathogens causing mycobacterial infections in pig herds.we defined the role of the syrphid fly eristalis tenax in the survival and transmission of mycobacteria in pigs. the conditionally pathogenic mycobacterial (cpm) species mycobacterium chelonae was isolated from 10 % of liquid dung samples, and both m. chelonae and another cpm species m. fortuitum were isolated from 7 (78 %) of the examined e. tenax larvae collected from the same location. mycobacteriosis of the lymph nodes of pigs from 3 infected farms was caused by m. avium subsp. avium, m. avi ...200616821726
[cutaneous infection due to mycobacterium chelonae in a hemodialysed patient].we report a case of a hemodialysed patient who developed a cutaneous mycobacterium chelonae infection. this infection was only localised on the left upper limb, downstream from the arteriovenous fistula. m. chelonae is an unusual human pathogen, which is present in soil, dust, and stagnant water. various factors, especially immunosuppression can favour this sort of infection in humans. because of the ubiquity of the mycobacterium, the source of the inoculation sometimes remains unknown. however, ...200616890138
pathogenesis of mycobacterium spp. in zebrafish (danio rerio) from research facilities.one of the most common diseases that we have diagnosed in zebrafish is mycobacteriosis, caused by several mycobacterium spp. the severity of the disease ranged from severe outbreaks to incidental infections. we conducted an in vivo study to evaluate the pathogenesis of six isolates of mycobacterium from zebrafish with mycobacteriosis from four research facilities and one wholesale supplier of zebrafish in the united states: mycobacterium abscessus, mycobacterium peregrinum, mycobacterium chelona ...200716904945
exogenous lipoid pneumonia superinfected with acid-fast bacilli in infants: a report of nine cases.super-infection of an exogenous lipoid pneumonia by nontuberculous mycobacteria has been described in the literature. it produces a distinctive histologic picture with suppurative, noncaseating granulomas surrounding lipid vacuoles containing acid-fast bacilli. mainly isolated cases have been found, but seldom in children. we describe a series of 9 children with similar histological findings. all our patients were under 1 year of age, malnourished, and with chronic respiratory symptoms. the diag ...200616908460
in vitro activities of the novel oxazolidinones da-7867 and da-7157 against rapidly and slowly growing mycobacteria.da-7867 and da-7157 are oxazolidinones active against pathogenic aerobic actinomycetes including nocardia spp. and mycobacterium tuberculosis. however, the activity of these drugs against nontuberculous mycobacterium (ntm) species is not known. in this work, we compared the susceptibilities of 122 clinical isolates and 29 reference species of both rapidly growing and slowly growing mycobacteria to linezolid, da-7867, and da-7157 by the broth microdilution method. the mics for 50 and 90% of the s ...200617015632
mycobacterium chelonae infection complicating cosmetic facial surgery. 200617034563
environmental mycobacteria in areas of high and low tuberculosis prevalence in the islamic republic of iran.this research compared the numbers and types of different mycobacterium species in soil samples taken from 2 areas of golestan province, islamic republic of iran, 1 with a high prevalence of tuberculosis and 1 with a low prevalence. from 220 samples, 91 grew positive cultures (41.4%) and 161 different strains were diagnosed. the most common species isolated were mycobacterium fortuitum, m. flavescens and m. chelonae. the frequencies of environmental mycobacterium in the low-prevalence area were ...200617037695
skin and soft tissue infections due to rapidly growing mycobacteria: comparison of clinical features, treatment, and susceptibility.to compare the demographics, clinical features, susceptibility patterns, and treatment for skin and soft tissue infections due to mycobacterium fortuitum and mycobacterium chelonae or mycobacterium abscessus.200617043183
hospital outbreak of atypical mycobacterial infection of port sites after laparoscopic surgery.a series of 145 laparoscopy port site infections due to mycobacterium chelonae were found in 35 patients following laparoscopy at a single hospital over a six-week period. the contaminating source was ultimately identified as the rinsing water used for washing chemically disinfected instruments. the organism survived and grew within the biofilm at the bottom of disinfectant trays and within the outer sleeves of re-usable laparoscopic instruments. remedial control measures included changing to et ...200617046106
relationships between mycobacterium isolates from patients with pulmonary mycobacterial infection and potting soils.high numbers of mycobacteria, including known pathogenic species such as mycobacterium avium, mycobacterium intracellulare, and mycobacterium chelonae, were recovered from aerosols produced by pouring commercial potting soil products and potting soil samples provided by patients with pulmonary mycobacterial infections. the dominant mycobacteria in the soil samples corresponded to the dominant species implicated clinically. profiles of large restriction fragments obtained by pulsed-field gel elec ...200617056679
mycobacterium chelonae synovitis. 200617072142
experimental evaluation of an automated endoscope reprocessor with in situ generation of peracetic acid for disinfection of semicritical devices.to evaluate the effectiveness of a high-level disinfection solution generated inside an endoscope processing system for decontaminating external and internal surfaces of experimentally contaminated heat-sensitive medical devices.200617080376
multiple subcutaneous nodules associate with mycobacterium abscessus infection following removal of an infected groshon vascular catheter tip.a 41-year-old man with a history of septic right leg underwent a below-the-knee amputation. one month after amputation and removal of groshon catheter tip, he developed disseminated subcutaneous abscesses attributed to mycobacterium abscessus.200617083867
a low incidence of nontuberculous mycobacterial infections in pediatric hematopoietic stem cell transplantation recipients.hematopoietic stem cell transplantation (hsct) is being used to treat a wide spectrum of clinical disorders but opportunistic infection remains an important factor determining outcomes for these patients. nontuberculous mycobacterial (ntm) infections are being reported more frequently in hsct recipients and the incidence of ntm infections in adult recipients is reported to be 0.4%-4.9%. however, the incidence and severity of ntm infections are less well described in pediatric hsct recipients. ce ...200617085312
conservative management of local mycobacterium chelonae infection after combined liposuction and lipofilling.a case of mycobacterium chelonae infection in the buttock after combined liposuction and lipoinjection is presented. the real possibility of contamination from operating room equipment was the potential etiologic factor of this infection. the clinical presentation of the disease was typical. the difficulty confirming the diagnosis was solved by specific culturing techniques. successful treatment with limited debridement and irrigation combined with prolonged specific antibiotic therapy effected ...200617093877
[assessment of the invasiveness of rapidly-growing nonpigmented mycobacteria with the fibroblast microcolony assay].the invasive capacity of rapidly-growing nonpigmented mycobacteria strains was evaluated by means of a fibroblast microcolony assay and related to the colony phenotype on middlebrook 7h11 and to the clinical significance of the isolates.200617125673
hypervirulence of a rough variant of the mycobacterium abscessus type strain.we isolated a rough variant of mycobacterium abscessus cip 104536t during experimental infection of mice. we show that this variant has lost the ability to produce glycopeptidolipids, is hyperlethal for c57bl/6 mice infected intravenously, and induces a strong tumor necrosis factor-alpha response by murine monocyte-derived macrophages.200717145951
[osteoarticular infections due to mycobacteria in a university hospital]. 200617194394
sweet's syndrome: a spectrum of unusual clinical presentations and associations.sweet's syndrome (ss) is the prototypic neutrophilic dermatosis. first described in 1964, the characterization of new clinical associations, unique histopathological findings and clinical variants have stimulated much interest and discussion recently. however, the prevalence of these unusual variants and clinical associations within a single cohort of patients, has not been described.200717300237
multifocal spinal and extra-spinal mycobacterium chelonae osteomyelitis in a renal transplant recipient.only localized cases of mycobacterium chelonae osteomyelitis have been reported. in this article, a 55-year-old immunosuppressed man with m. chelonae osteomyelitis and multiple spinal and extra-spinal involvement is presented. the patient had nodule-pustular skin lesions, spondylodiscitis at multiple levels, and osteolytic lesions at extra-spinal locations. biopsy and cultures of the osseous lesions showed m. chelonae osteomyelitis. the patient started antimycobacterial chemotherapy with ciprofl ...200717313477
aerosolized amikacin for treatment of pulmonary mycobacterium avium infections: an observational case series.current systemic therapy for nontuberculous mycobacterial pulmonary infection is limited by poor clinical response rates, drug toxicities and side effects. the addition of aerosolized amikacin to standard oral therapy for nontuberculous mycobacterial pulmonary infection may improve treatment efficacy without producing systemic toxicity. this study was undertaken to assess the safety, tolerability and preliminary clinical benefits of the addition of aerosolized amikacin to a standard macrolide-ba ...200717319962
atypical presentation of atypical organism. 200717351311
in vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in taiwan.the in vitro activities of isepamicin against 117 mycobacteria abscessus, 48 mycobacterium fortuitum, and 20 mycobacterium chelonae isolates were evaluated by a microdilution test. isepamicin mic(90)s were < or =16 microg/ml for the three species. isepamicin was as active as amikacin and kanamycin and more active than tobramycin, capreomycin, gentamicin, and streptomycin.200717353252
cutaneous mycobacterium chelonae infection in chronic lymphocytic leukaemia. 200717405741
identification of an emerging pathogen, mycobacterium massiliense, by rpob sequencing of clinical isolates collected in the united states.mycobacterium massiliense is a rapidly growing mycobacterium that is indistinguishable from mycobacterium chelonae/m. abscessus by partial 16s rrna gene sequencing. we sequenced rpob, soda, and hsp65 genes from isolates previously identified as being m. chelonae/m. abscessus and identified m. massiliense from isolates from two patients with invasive disease representing the first reported cases in the united states.200717409204
mycobacterium chelonei mastitis in a quebec dairy herd.an epizootic of bovine mastitis caused by a nontuberculous mycobacterial agent occurred in a large quebec dairy herd. this mastitis problem was characterized by the occurrence of a high number of cows with severely inflamed, indurated and therapeutically incurable quarters. routine diagnostic laboratory methods yielded negative cultural findings. approximately 40% of the milking cows developed chronic mastitis. poor sanitation, improper milking procedures and a faulty milking system prevailed at ...198317422316
[atypical mycobacteriosis of the skin caused by mycobacterium abscessus in an immunocompetent woman].mycobacterium abscessus is the most pathogenic of the fast-growing mycobacteria, and it is resistant to most of the antimicrobial and tuberculostatic drugs available. this non-tuberculous mycobacterium is significant in medicine because it can contaminate post-traumatic wounds and be a causative agent in chronic skin and soft tissue infection after surgical procedures.a 60-year-old immunocompetent woman was suffering from chronic ulcers and abscesses on the heels and malleoli of both feet. histo ...200717429583
a paradigm for the molecular identification of mycobacterium species in a routine diagnostic laboratory.the aim of this study was to improve the identification of mycobacterium species in the context of a uk teaching hospital. real-time pcr assays were established to enable the rapid differentiation between mycobacterium tuberculosis (mtb) complex and mycobacterium species other than tuberculosis (mott), followed by 16s rrna gene sequencing for the speciation of mott. real-time pcr assays gave comparable results to those from the reference laboratory. the implementation of these pcr assays using a ...200717446280
genomics of glycopeptidolipid biosynthesis in mycobacterium abscessus and m. chelonae.the outermost layer of the bacterial surface is of crucial importance because it is in constant interaction with the host. glycopeptidolipids (gpls) are major surface glycolipids present on various mycobacterial species. in the fast-grower model organism mycobacterium smegmatis, gpl biosynthesis involves approximately 30 genes all mapping to a single region of 65 kb.200717490474
nontuberculous mycobacteria infection after mesotherapy: preliminary report of 15 cases.mesotherapy is an increasingly used technique which is currently causing several mycobacterial infections owing to contaminated substances being injected, and also to poor aseptic measures being held by nonprofessional practitioners.200717550571
nontuberculous mycobacterial peritonitis in peritoneal dialysis patients.while nontuberculous mycobacterial peritonitis is uncommon among peritoneal dialysis (pd) patients, these infections have serious consequences. they present a significant diagnostic and therapeutic challenge for clinicians. diagnosis can be delayed due to the slow growth rate of some mycobacterial species. these organisms can also be overlooked when adequate culture media are not used in the microbiological evaluation process. the choice of antimicrobial therapy depends upon isolation and specia ...200717555495
in response to: sathiakar paul collison, naresh trehan. native double-valve endocarditis by mycobacterium fortuitum following percutaneous coronary intervention. j heart valve dis 2006;15:836-838. 200717578059
postoperative infection of laparoscopic surgery wound due to mycobacterium chelonae.we report a case of postoperative wound infection due to mycobacterium chelonae. a 35-year-old woman presented with multiple erythematous nodules, plaques and discharging sinuses over the abdomen, 45 days after she had undergone laparoscopic ovarian cystectomy. the seropurulent discharge from the wound showed acid-fast bacilli on ziehl- neelsen stain and culture yielded mycobacterium chelonae. the patient responded to clarithromycin and doxycycline. the source of infection was probably contamina ...200717582193
atypical mycobacteria keratitis after laser in situ keratomileusis unresponsive to fourth-generation fluoroquinolone therapy.we report a case of post-laser in situ keratomileusis atypical mycobacteria infection unresponsive and resistant to fourth-generation fluoroquinolones, which highlights the importance of a high level of suspicion and the need for multidrug therapy for effective eradication.200717586393
a cluster of rapidly growing mycobacterial peritoneal dialysis catheter exit-site infections.in this case series, a cluster of 5 consecutive peritoneal dialysis patients with atypical mycobacterial exit-site infections in a single center within 20 months are described. clinical features, treatment, and outcomes are discussed. most patients had been treated with prolonged systemic antibiotic therapy for recurrent bacterial exit-site infections in the preceding months, and all had used topical gentamicin ointment for exit-site infection treatment or prophylaxis. it is postulated that this ...200717591517
in-vitro evaluation of the adhesion to polypropylene sutures of non-pigmented, rapidly growing mycobacteria.the ability of non-pigmented, rapidly growing mycobacteria (nprgm) to attach to polypropylene sutures was evaluated using an in-vitro assay. thirty clinical isolates and five culture collection strains of nprgm, together with staphylococcus epidermidis atcc 35983, were tested. mycobacterium fortuitum and mycobacterium chelonae showed the highest attachment ability, which differed significantly from the results obtained with mycobacterium peregrinum. according to these results, nprgm are able to ...200717608747
skin and joint infection by mycobacterium chelonae: rescue treatment with interferon gamma.atypical mycobacteria are environmental organisms that cause opportunistic infections in humans.200717613267
dissemination of a localized cutaneous infection with mycobacterium chelonae under immunosuppressive treatment. 200717638751
mycobacterium chelonei: friend or foe? 200717666565
prosthetic joint infection due to rapidly growing mycobacteria: report of 8 cases and review of the literature.prosthetic joint infection (pji) due to rapidly growing mycobacteria (rgm) is only occasionally encountered in clinical practice. therefore, the optimal clinical management for this condition is unknown.200717712751
infections with atypical mycobacteria in renal transplant recipients.infections due to atypical mycobacteria are infrequent in renal transplant recipients but they cause serious morbidity. these pathogens are common in patients with acquired immune deficiency syndrome (aids). we report four proven cases of infections caused with atypical mycobacteriae from 1997 to 2003, by different organisms namely, m. chelonei, m.fortuitum, m. abcessus and m. terrae in renal transplant recipients. infection with m. terrae documented here is the first occurrence in a renal trans ...200717883113
association of mycobacteria with eales' disease.eales' disease is an idiopathic disease resulting in retinal neovascularization, recurrent haemorrhages, with or without retinal detachment predominantly affecting healthy young males (97.6%) in the indian subcontinent. inspite of several studies, the aetiology of eales' disease is not clear. the isolation of mycobacterium fortuitum from the aqueous humour of a patient with classical eales' disease, led us to hypothesize that rapid growing nontuberculous mycobacteria (rgntm), particularly m. for ...200717890825
[experimental study of non-tuberculous mycobacterial keratitis in rabbits].to study clinical manifestation and pathology change of different time points of rabbit keratitis caused by non-tuberculous mycobacteria (ntm).200717897550
treatment of water-based metalworking fluids to prevent hypersensitivity pneumonitis associated with mycobacterium spp.to prevent further outbreaks of hypersensitivity pneumonitis (hp), biocides are required which are capable of protecting water-based coolants from proliferating mycobacteria. the aim of this study was therefore, to test different biocide preparations on their mycobactericidal activity.200817961156
the increasing problem of antibiotic resistance. 200717964369
fourth-generation fluoroquinolone-resistant mycobacterial keratitis after laser in situ keratomileusis.we report a case of mycobacterial keratitis resistant to fourth-generation fluoroquinolones after laser in situ keratomileusis (lasik) with fourth-generation fluoroquinolone prophylaxis. while receiving moxifloxacin post lasik, the patient was diagnosed with moxifloxacin-resistant mycobacterium chelonae keratitis. culture susceptibilities revealed isolates resistant to moxifloxacin and gatifloxacin, and treatment with topical amikacin and clarithromycin with oral doxycycline and clarithromycin a ...200717964409
[renal mycobacteriosis].there is a number of specific infections due to opportunistic mycobacteria which normally exist as environmental saprophytes. among them, renal mycobacteriosis is a disease similar to renal tuberculosis. the obvious causative agents are some mycobacteria: mycobacterium chelonei, mycobacterium fortuitum, mycobacterium xenopi, mycobacterium kansasii, mycobacterium avium complex, and mycobacterium simiae. it is not easy to prove that a renal disease is of mycobacterial origin. we suggest some crite ...199417972827
molecular systematics support the revival of mycobacterium salmoniphilum (ex ross 1960) sp. nov., nom. rev., a species closely related to mycobacterium chelonae.mycobacterial infections in fish are usually attributed to strains of mycobacterium marinum, mycobacterium chelonae and mycobacterium fortuitum. bacteria identified as m. chelonae have been isolated numerous times from salmonid fishes. recently, this bacterium has been associated with salmon mortalities in the aquaculture industry. an m. chelonae-like species from salmon, 'mycobacterium salmoniphilum', was described in 1960. however, the species name lost standing in nomenclature when it was omi ...200717978213
species of environmental mycobacteria differ in their abilities to grow in human, mouse, and carp macrophages and with regard to the presence of mycobacterial virulence genes, as observed by dna microarray hybridization.there are many species of environmental mycobacteria (em) that infect animals that are important to the economy and research and that also have zoonotic potential. the genomes of very few of these bacterial species have been sequenced, and little is known about the molecular mechanisms by which most of these opportunistic pathogens cause disease. in this study, 18 isolates of em isolated from fish and humans (including strains of mycobacterium avium, mycobacterium peregrinum, mycobacterium chelo ...200817981953
[case of pulmonary infection with mycobacterium chelonae in healthy breast-feeding woman].we report a case of pulmonary infection caused by mycobacterium chelonae. the patient was a healthy breastfeeding 29 year-old female. an abnormal shadow had been pointed out by the chest x-ray in the regular checkup of the office workers. the chest x-ray film showed consolidation at right lower lung field, which initially suggested pulmonary tuberculosis. the chest ct scan showed scattered consolidation. smears and cultures of the sputum were repeatedly positive for mycobacteria, which was ident ...200718018600
disseminated cutaneous mycobacterium chelonae infection with multidrug resistance in a patient with panuveitis.we report the case of a 43-year-old immunosuppressed woman who presented with cellulitis of the lower limbs and multiple widespread subcutaneous nodules in a sporotrichoid distribution. microbiological findings from skin biopsy confirmed mycobacterium chelonae infection.200818021269
leg ulcers in a 38-year-old female. 200718032961
infection of total hip prosthesis by mycobacterium tuberculosis and mycobacterium chelonae in a patient with rheumatoid arthritis.atypical mycobacterial infections of the musculoskeletal system are very rare and are generally associated with predisposing factors, such as trauma, use of corticosteroids, or an immunocompromised state. there have only been three reports of mycobacterium chelonae prosthetic infection of which two cases were associated with total hip arthroplasty and one with total knee arthroplasty and no reports of both mycobacterium tuberculosis and m. chelonae occurring in the same joint. we report a case o ...200818034202
comparison of the bacteriostatic effects, corneal cytotoxicity, and the ability to seal corneal incisions among three different tissue adhesives.to compare the bacteriostatic effects, corneal cytotoxicity, and ability to seal corneal incisions among fibrin glue and 2 commercially available cyanoacrylate derivatives: n-butyl cyanoacrylate and methoxypropyl cyanoacrylate.200718043181
bilateral nontuberculous mycobacterial keratitis after laser in situ keratomileusis. 200718067772
generation of resistant mutants of mycobacterium chelonae and mycobacterium fortuitum after exposure to subinhibitory concentrations of clarithromycin and moxifloxacin. 200718073162
successful treatment of cutaneous mycobacterium chelonae infection with roxithromycin. 200718078414
stenotrophomonas maltophilia and mycobacterium chelonae coinfection of the extraocular scleral buckle explant.to report a very unusual form of coinfection of the extraocular scleral buckle explant by stenotrophomonas maltophilia and mycobacterium chelonae.200718085488
[a case of pulmonary infection due to mycobacterium chelonae treated by lobectomy after a long course of oral antimicrobial agents].small nodular shadows were pointed out in right upper lobe and middle lobe on the chest radiograph of a 60-year-old woman in 1992. mycobacterium chelonae was isolated from bronchoalveolar lavage (bal) fluid in 1994. long term antimicrobial chemotherapy with rifampicin, ethambutol, clarithromycin and quinolone antibiotics was then started. the chest radiograph, however, revealed infiltration in the right upper and middle lobes and the isolated strain was found to be resistant to antimicrobials in ...200718186246
outbreak of persistent cutaneous abscesses due to mycobacterium chelonae after mesotherapy sessions, lima, peru.outbreaks of rapidly growing mycobacteria have been occasionally described. the article reports an outbreak of cutaneous abscesses due to mycobacterium chelonae following mesotherapy in lima, peru. from december 2004 through january 2005, 35 subjects who had participated in mesotherapy training sessions presented with persistent cutaneous abscesses. thirteen (37%) of these suspected cases consented to undergo clinical examination. skin punch-biopsies were collected from suspicious lesions and su ...200818200353
atypical canaliculitis.a 34-year-old immunocompetent woman sought treatment for a 6-week history of right inferior medial canthal swelling and discharge consistent with canaliculitis. symptoms persisted after conservative medical therapy. after canaliculotomy and removal of a dacryolith, the patient experienced resolution of signs and symptoms. although actinomyces has been a frequently reported cause of canaliculitis, we report a unique case of canaliculitis caused by mycobacterium chelonae.200818209646
the organization of two rrna (rrn) operons of the slow-growing pathogen mycobacterium celatum provides key insights into mycobacterial evolution.the slow-growing mycobacterium celatum is known to have two different 16s rrna gene sequences. this study confirms the presence of two rrn operons and describes their organization. one operon (rrna) was found to be located downstream from mura and the other (rrnb) was found downstream from tyrs. the promoter regions were sequenced, and also the intergenic transcribed spacer (its1 and its2) regions separating the 16s rrna, 23s rrna and 5s rrna gene coding regions. analysis of the rna fraction rev ...200818248431
chronic knee monoarthritis caused by mycobacterium chelonae.extrapulmonary tuberculosis occurs in 20% of all patients with tuberculosis and tubercular arthritis occurs in 10% of those with extrapulmonary tuberculosis. arthritis caused by mycobacterium tuberculosis is not uncommon in india. however, arthritis caused by mycobacterium chelonae has not been reported to the best of our knowledge. we report a patient with arthritis caused by mycobacterium chelonae in whom the diagnosis was confirmed by smear and culture of acid-fast bacilli. polymerase chain r ...200718254520
mycobacterium chelonae keratitis in a patient with sjögren's syndrome.in this report a case of mycobacterium chelonae keratitis in a patient without any previously described risk factors is described. the only risk factor found was a rheumatoid arthritis related sjogren''s syndrome.200818320526
[cutaneous non-tuberculous mycobacterial infection following cord blood stem cell transplantation].we describe a 4-year-old-girl with familial hemophagocytic lymphohistiocytosis (fhl) who developed disseminated cutaneous nontuberculous mycobacterial (ntm) infection after unrelated cord blood stem cell transplantation (ucbsct). after transplantation, the patient developed steroid-refractory acute graft-versus-host disease, and was given methylprednisolone, cyclosporin and mycophenolate mofetil. six months after ucbsct, cutaneous lesions that looked like insect bites appeared and spread widely ...200818341040
retroperitoneal cold abscess caused by mycobacteria chelonae abscessus after percutaneous nephrolithotomy in india: strategies for detection, management, and prevention in the united states.atypical, nontuberculous, mycobacteria (ntm) are emerging as significant pathogens in nosocomial infections. historically, such outbreaks have been limited to developing countries, and clinicians in the united states have not been exposed to the nuances of diagnosing and treating such infections. with an increasing prevalence worldwide, all clinicians should be able to recognize and treat ntm infections. we report a case of a patient who developed a retroperitoneal cold abscess caused by ntm aft ...200918343485
in vitro bactericidal activity of antibiotic combinations against clinical isolates of mycobacterium chelonae.mycobacterium chelonae is one of the most antibiotic-resistant species of the pathogenic, rapidly-growing mycobacteria. the objective of this study was to evaluate the bactericidal activity of classical and new potential drugs, alone and in combinations, against clinical isolates of mycobacterium chelonae. clarithromycin was seen to be the most bactericidal drug. in drug combinations, this compound is most useful with gentamicin, fluoroquinolones, rifampicin, linezolid, other aminoglycosides, do ...200818343742
mycobacterium chelonae peritonitis in a patient on peritoneal dialysis.non-tuberculous mycobacteria peritonitis is uncommon with the majority of cases reported in patients on peritoneal dialysis with diagnostic and therapeutic challenges. here we present a case of mycobacterium chelonae peritonitis and review other cases in the literature to discuss the clinical spectrum, diagnostics, regimens and duration of treatment, and outcome.200818350455
mycobacterium chelonae infection associated with adalimumab therapy. 200818415777
[hypersensitivity pneumonitis associated with mycobacterium chelonae]. 200818423186
body piercing complicated by atypical mycobacterial infections.body piercing is a growing trend, especially in young people, but the literature on complications of piercing consists mostly of case reports involving ear piercing. previous reported complications of piercing include contact dermatitis, keloids, traumatic tearing, viral transmission, and bacterial infections. we report two patients who presented with atypical mycobacterial infections of body piercing sites. it is important to recognize the association of piercing and mycobacterial infections so ...200818429784
mycobacterium chelonae empyema in an immunocompetent patient.thoracic empyema caused by rapidly growing mycobacteria (rgm) and complicated with bronchopleural fistula is rarely reported, especially in immunocompetent patients. a 53-year-old healthy woman presented initially with a productive cough and intermittent fever. the patient received a complete treatment course following an initial diagnosis of pulmonary tuberculosis. after the anti-tuberculosis agents were discontinued, a right thoracic empyema with bronchopleural fistula occurred, and the pathog ...200818436603
antimicrobial resistance of rapidly growing mycobacteria in western taiwan: smart program 2002.to understand the resistance patterns of rapidly growing mycobacteria (rgm) in taiwan, antimicrobial resistance of clinical isolates was determined as part of the smart (surveillance from multicenter antimicrobial resistance in taiwan) program.200818445541
mycobacterium chelonei breast abscess associated with nipple piercing.breast abscesses are typically seen in the setting of complicated mastitis in lactating women. abscesses resulting from foreign bodies are not commonly seen in the breast. over the past few decades, body piercing has become increasingly common, yet the infectious morbidity resulting from it is not well recognized. a breast abscess associated with nipple piercing is described in this report.199518476032
sutureless wound infection by unusual acid-fast organisms.to report infection of self-sealing wounds in cataract surgery by unusual acid-fast organisms.200818520516
mycobacterium chelonae canaliculitis associated with smartplug use.mycobacterium chelonae is ubiquitous in the environment but is an uncommon cause of ocular and periocular infections. it is a pathogen that has been gaining increased attention in the ophthalmic literature because of the relatively large number of infections associated with laser-assisted in situ keratomileusis and other forms of refractive surgery. the authors present 3 patients who developed canaliculitis culture positive for m. chelonae more than a year after smartplug placement. these cases ...200818520851
[susceptibility to antimicrobial agents of rapidly growing mycobacteria].rapidly growing mycobacteria are often associated with human diseases. we investigated the in vitro susceptibilities of 40 isolates to six antimicrobial agents: 17 mycobacterium fortuitum, 11 m. chelonae and 12 m. abscessus isolated from several human sources: 29 respiratory secretions, 5 cutaneous abscesses, 4 corneal ulcers and 2 urine samples of patients treated at "hospital puerta del mar" (cádiz). susceptibility studies were determined by the broth microdilution method for amikacin, clarith ...200718563216
importation of mycobacteriosis with ornamental fish: medico-legal implications.mycobacterium fortuitum, as well as mycobacterium marinum and mycobacterium chelonae, are the etiological agents of fish mycobacterioses. mycobacteriosis has been reported to affect a wide range of freshwater and marine fish species, suggesting an ubiquitous distribution, and can cause zoonotic infections (known as "fish tank granuloma" or "swimming pool granuloma") in humans exposed to fish and contaminated water. infection in human consists of nodular cutaneous lesions that can progress to ten ...200818571116
survival of enveloped and non-enveloped viruses on surfaces compared with other micro-organisms and impact of suboptimal disinfectant exposure.survival of enveloped and non-enveloped viruses was compared with that of bacteria, yeasts and mycobacteria when dried on the surface of polyvinyl chloride test carriers in the presence or absence of an organic matrix. the efficacy of glutaraldehyde and accelerated hydrogen peroxide (ahp) disinfectants was evaluated. reovirus, a non-enveloped virus, persisted and had a rf of 2 after 30 days whereas enterococcus faecalis had an rf of 4 over the same time period. the other test organisms (sindbis ...200818602193
drug susceptibility of the mycobacterium genus: in vitro tests and clinical implications.this review describes the mechanisms of drug resistance of the most clinically relevant mycobacteria and the methods that have been used for studying drug susceptibility (pnenotype, genotype and in vivo tests) and it describes the more important resistance mechanisms to the drugs. also, this review describes the relationship between microbiological and pharmacological data and the importance of latency -stationary phase- in mycobacteria. current clinical guidelines on the treatment of tuberculos ...200618666752
necessary corrections to the approved lists of bacterial names according to rule 40d (formerly rule 46). opinion 86.the judicial commission affirms that, according to rule 40d, formerly rule 46, of the bacteriological code, the authorship of a number of subspecies names included on the approved lists of bacterial names must be corrected. these names are acetobacter aceti subsp. aceti, acetobacter pasteurianus subsp. pasteurianus, bacteroides melaninogenicus subsp. melaninogenicus, campylobacter fetus subsp. fetus, mycobacterium chelonae subsp. chelonae, propionibacterium freudenreichii subsp. freudenreichii, ...200818676492
proportions of mycobacterium massiliense and mycobacterium bolletii strains among korean mycobacterium chelonae-mycobacterium abscessus group isolates.korean isolates of the mycobacterium chelonae-mycobacterium abscessus group, which had been isolated from two different hospitals in south korea, were identified by pcr restriction analysis (pra) and comparative sequence analysis of 16s rrna genes, rpob, and hsp65 to evaluate the proportion of four closely related species (m. chelonae, m. abscessus, m. massiliense, and m. bolletii). of the 144 rapidly growing mycobacterial strains tested, 127 strains (88.2%) belonged to the m. chelonae-m. absces ...200818753344
disseminated panniculitis in a bottlenose dolphin (tursiops truncatus) due to mycobacterium chelonae infection.a 14-year-old female bottlenose dolphin was diagnosed with mycobacterial panniculitis based on punch biopsy specimens. the necropsy revealed numerous pyogranulomas in the blubber, as well as marked acute multifocal necrosuppurative pneumonia and lymphadenitis. in addition, the animal had marked scoliosis, which had first been noted clinically in the dolphin at about 1 mo of age. the animal had been treated with low-dose dexamethasone for approximately the last 19 mo to reduce perceived discomfor ...200818817005
disseminated infection due to mycobacterium chelonae with scleritis, spondylodiscitis and spinal epidural abscess.mycobacteria other than tuberculosis (mott) have a low incidence as pathogens in human pathology. the most frequent clinical expression is the disseminated disease in subjects with compromised cellular immunity. bacteriological characteristics in culture can generate confusion with other pathogens, which delays the appropriate diagnosis and treatment. we present a case of a disseminated infection due to mycobacterium chelonae with scleritis, spondylodiscitis and spinal epidural abscess in a man ...200818833414
mycobacterium chelonae infection following silicone arthroplasty of the metacarpophalangeal joints: a case report.we present a case of infection caused by an uncommon pathogen, mycobacterium chelonae, in a patient that underwent swanson silicone arthroplasty of the metacarpophalangeal joints for rheumatoid arthritis. this is the first report of an infection caused by nontuberculous mycobacteria in flexible silicone implants in the hand. the patient was successfully treated with implant removal, debridement, and antimicrobials tailored to the results of in vitro susceptibility testing.200918843521
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