| [effect of mycobacterium phlei f.u.36 on balance of cd4⁺cd25⁺ regulatory t cells and th17 cells in asthmatic mice]. | to evaluate the effect of early intervention with mycobacterium phlei f.u.36 injection on the balance of cd4⁺cd25⁺ regulatory t cells and th17 cells in asthmatic mice, and to investigate the immunomodulatory effect of mycobacterium phlei f.u.36. | 2013 | 24229602 |
| isolation, purification and characterization of cardiolipin synthase from mycobacterium phlei {private}. | it has been observed that mycobacterial species has high content of cardiolipin (cl) in their cell membranes more so pathogenic mycobacteria and in bacteria cl activates polymerases, gyrases by removing the bound adp. therefore, in the present study cardiolipin synthase (cls) which catalyses the formation of cl was isolated purified and characterized from the cell membrane of mycobacterium phlei. the purified cls obtained from c-18 rp-hplc column had a molecular weight of 58 kda with an isoelect ... | 2013 | 23930021 |
| effect of inhaled inactivated mycobacterium phlei in children with moderate asthma. | bacillus calmette-guérin and other mycobacterial vaccines are important therapeutic methods in a series of chronic inflammatory disorders characterized by th1/th2 imbalance in which th2 type cells and cytokines often increase. however, few studies have investigated whether it can reduce or prevent the symptoms and attacks in children with asthma. this study evaluated the effect of inactivated mycobacterium phlei inhaled by an atomizing device placed on asthmatic children. in this randomized, sin ... | 2013 | 23413910 |
| complete genome sequence of mycobacterium phlei type strain rivm601174. | mycobacterium phlei is a rapidly growing nontuberculous mycobacterium species that is typically nonpathogenic, with few reported cases of human disease. here we report the whole genome sequence of m. phlei type strain rivm601174. | 2012 | 22628511 |
| low levels of residual oil fly ash (rofa) impair innate immune response against environmental mycobacteria infection in vitro. | epidemiological studies have shown that pollution derived from industrial and vehicular transportation provokes adverse health effects causing broad spectrum of ambient respiratory diseases. therefore, air pollution should be taken into account when microbial diseases are evaluated. environmental mycobacteria (em) are opportunist pathogens in a variety of immunocompromised patients eliciting significant impact on human morbidity and mortality. the aim of this study was to evaluate the in vitro e ... | 2012 | 22548959 |
| therapeutic effects of inhaled inactivated mycobacterium phlei in adult patients with moderate persistent asthma. | bcg and other mycobacterial infections suppress airway hyper-responsiveness and inflammation in asthma models; however, its efficacy in human populations remains controversial. we use inactivated mycobacterium phlei by way of atomizing inhalation to investigate whether it would protect against asthma in adult patients. patients with newly diagnosed, uncontrolled, moderate persistent bronchial asthma were randomly divided into two groups. the patients in group a were treated with a solution of in ... | 2012 | 22512632 |
| enzymatic phosphorylation of mannose by glucomannokinase from mycobacterium phlei using inorganic polyphosphate. | mannose-6-phosphate is an important phosphor-sugar, which is involved in many physiological functions and it is used to treat many diseases. its production is however expensive since it requires costly substrate atp as phosphorylation agent. this study has focused upon the direct synthesis of m6p by glucomannokinase using inorganic polyphosphate without involvement of atp. the gene cloned for glucomannokinase has been sequenced from mycobacterium phlei and it is transformed into escherichia coli ... | 2017 | 28648175 |
| immunogenicity and therapeutic effects of recombinant ag85ab fusion protein vaccines in mice infected with mycobacterium tuberculosis. | the immune function of tuberculosis (tb) patients is disordered. by using immune regulators to assist chemotherapy for tb the curative effect might be improved. in this study, a vaccine containing mycobacterium tuberculosis (m. tuberculosis) recombinant ag85ab fusion protein (rag85ab) was constructed and evaluated. the mice were immunized intramuscularly three times at two-week intervals with ag85ab fusion protein combined with corynebacterium parvum adjuvant (rag85ab+cp). in comparison to contr ... | 2017 | 28625522 |