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bacteriophage application restores ethanol fermentation characteristics disrupted by lactobacillus fermentum.contamination of corn mash by lactic acid bacteria (lab) reduces the efficiency of the ethanol fermentation process. the industry relies heavily on antibiotics for contamination control and there is a need to develop alternative methods. the goals of this study were to determine the diversity and abundance of bacteria contaminating commercial ethanol fermentations, and to evaluate the potential of anti-lab bacteriophages in controlling production losses.201526339290
lactobacillus fermentum ncimb 5221 and ncimb 2797 as cholesterol-lowering probiotic biotherapeutics: in vitro analysis.cardiovascular and coronary artery disease risk are correlated with cholesterol levels and are significant health concerns. current cholesterol-lowering approaches includes lifestyle and diet modifications, as well as statins which presents numerous shortcomings. the probiotic bacteria, lactobacillus fermentum ncimb 5221 and ncimb 2797, have demonstrated cholesterol-lowering potential in animal studies. however, there is a lack in understanding the mechanism(s) behind these observed effects. the ...201526322545
draft genome sequence of lactobacillus fermentum nb-22.we announce here a draft genome sequence of lactobacillus fermentum nb-22, a strain isolated from human vaginal microbiota. the assembled sequence consists of 190 contigs, joined into 137 scaffolds, and the total size is 2.01 mb.201526272572
antihypertensive effects of probiotics lactobacillus strains in spontaneously hypertensive rats.the cardiovascular effects of probiotics lactobacillus fermentum cect5716 (lc40), or l. coryniformis cect5711 (k8) plus l. gasseri cect5714 (lc9) (1:1) in spontaneously hypertensive rats (shr) were evaluated.201526255877
preventive effect of lactobacillus fermentum zhao on activated carbon-induced constipation in mice.the aim of this study was to investigate the effects of lactobacillus fermentum zhao (lf-zhao) on activated carbon-induced constipation in icr mice. icr mice were administered lactic acid bacteria by gavage for 9 d. body weight, diet intake, drinking amount, stool status, gastrointestinal transit distance and stool time, in addition to motilin (mtl), gastrin (gas), endothelin (et), somatostatin (ss), acetylcholinesterase (ache), substance p (sp) and vasoactive intestinal peptide (vip) levels in ...201526052143
development of a quantitative pcr assay for rapid detection of lactobacillus plantarum and lactobacillus fermentum in cocoa bean fermentation.to monitor dominant species of lactic acid bacteria during cocoa bean fermentation, i.e. lactobacillus plantarum and lactobacillus fermentum, a fast and reliable culture-independent qpcr assay was developed. a modified dna isolation procedure using a commercial kit followed by two species-specific qpcr assays resulted in 100% sensitivity for l. plantarum and l. fermentum. kruskal-wallis and post-hoc analyses of data obtained from experiments with cocoa beans that were artificially spiked with de ...201526026241
electrochromic polyoxometalate material as a sensor of bacterial activity.lactobacillus fermentum, a bacterium of human microbiota, acts as an electron donor for the electrochromic [p2mo(vi)18o62](6-). since the reductive capacity of l. fermentum correlates with its metabolic activity, the reaction with [p2mo(vi)18o62](6-) affords a means of evaluating its activity. following this logic, we have concluded that vancomycin severely affects the activity of l. fermentum whereas omeprazole does not.201526007305
dietary maillard reaction products and their fermented products reduce cardiovascular risk in an animal model.this study examined the effects of maillard reaction products (mrp) and mrp fermented by lactic acid bacteria on antioxidants and their enhancement of cardiovascular health in icr mouse and rat models. in previous in vitro studies, the selected lactic acid bacteria were shown to significantly affect the activity of mrp. the expression of genes (e.g., superoxide dismutase, catalase, and glutathione peroxidase) related to antioxidant activity was upregulated by maillard-reacted sodium caseinate (c ...201526004833
probiotic attributes of lactobacillus fermentum isolated from human feces and dairy products.the objective of this study was to characterize native lactobacillus fermentum isolates for their probiotic attributes. accordingly, 12 l. fermentum isolates selected from indigenous fermented dairy products and infant fecal samples were evaluated for their probiotic properties by in vitro and pcr methods. the cultures exhibited high tolerance to acid and bile as well as survival in simulated transit fluids (above 70 %). cell surface hydrophobicity was in the range of 0.55-57.69 % for xylene and ...201526004804
lactobacillus fermentum zyl0401 attenuates lipopolysaccharide-induced hepatic tnf-α expression and liver injury via an il-10- and pge2-ep4-dependent mechanism.lipopolysaccharide (lps) has essential role in the pathogenesis of d-galactosamine-sensitized animal models and alcoholic liver diseases of humans, by stimulating release of pro-inflammatory mediators that cause hepatic damage and intestinal barrier impairment. oral pretreatment of probiotics has been shown to attenuate lps-induced hepatic injury, but it is unclear whether the effect is direct or due to improvement in the intestinal barrier. the present study tested the hypothesis that pretreatm ...201525978374
draft whole-genome sequence of lactobacillus fermentum lfqi6, derived from the human microbiome.we report a 2.21-mbp draft whole-genome sequence of lactobacillus fermentum qi6 (lfqi6). this strain demonstrates activity against pathogenic biofilms, enhances the skin barrier, and upregulates innate immune defenses. the genome sequence information of this strain will help to identify molecules that hold promise for the discovery of novel therapeutics for dermatological disorders.201525977424
lactobacillus fermentum agr1487 cell surface structures and supernatant increase paracellular permeability through different pathways.lactobacillus fermentum is commonly found in food products, and some strains are known to have beneficial effects on human health. however, our previous research indicated that l. fermentum agr1487 decreases in vitro intestinal barrier integrity. the hypothesis was that cell surface structures of agr1487 are responsible for the observed in vitro effect. agr1487 was compared to another human oral l. fermentum strain, agr1485, which does not cause the same effect. the examination of phenotypic tra ...201525943073
antibacterial activity of lactobacillus spp. isolated from the feces of healthy infants against enteropathogenic bacteria.lactobacilli are normal microflora of the gastrointestinal (gi) tract and are a heterogeneous group of lactic acid bacteria (lab). lactobacillus strains with probiotic activity may have health benefits for human. this study investigates the probiotic potential of lactobacillus strains obtained from the feces of healthy infants and also explores antibacterial activity of lactobacillus strains with probiotic potential against enteropathogenic bacteria. fecal samples were collected from 95 healthy ...201525930687
lactobacillus fermentum 3872 genome sequencing reveals plasmid and chromosomal genes potentially involved in a probiotic activity.in this report we describe a lactobacillus fermentum 3872 plasmid (plf3872) not previously found in any other strain of this species. the analysis of the complete sequence of this plasmid revealed the presence of a gene encoding a large collagen-binding protein (cbp), as well as the genes responsible for plasmid maintenance and conjugation. potential roles of cbp and a chromosomally encoded fibronectin-binding protein (fbpa) in probiotic activity are discussed.201525908870
lactobacillus fermentum ns9 restores the antibiotic induced physiological and psychological abnormalities in rats.gut microbiota play a vital role in maintaining the health of the host. many factors affect gut microbiota; application of broad range antibiotics disturb microbiota, while probiotic application protects the microbiota. to investigate how probiotics alter the physiological and psychological changes induced by antibiotics, we tested the performance of ampicillin-treated rats in the presence or absence of lactobacillus fermentum strain ns9, in elevated plus maze and morris water maze. the results ...201525869281
development of gastro-resistant tablets for the protection and intestinal delivery of lactobacillus fermentum cect 5716.different studies have attributed health benefits to lactobacillus fermentum cect 5716. however, the main problem associated with probiotics, is their low resistance to environmental and technological factors. actually, probiotics are marketed as capsules or sachets, but few probiotic tablets exist. the aim of this study was to design tablets made out of functional polymers (formula 1: methocel k-15-sodium alginate; formula 2: eudragit(®) l-100-sodium alginate; formula 3: cellulose acetate phtha ...201525843758
early-life establishment of the swine gut microbiome and impact on host phenotypes.early bacterial colonization and succession within the gastrointestinal tract has been suggested to be crucial in the establishment of specific microbiota composition and the shaping of host phenotype. here, the composition and dynamics of faecal microbiomes were studied for 31 healthy piglets across five age strata (days 14, 36, 48, 60 and 70 after birth) together with their mothers. faecal microbiome composition was assessed by 16s rrna gene 454-pyrosequencing. bacteroidetes and firmicutes wer ...201525727666
the viability of lactobacillus fermentum cect5716 is not essential to exert intestinal anti-inflammatory properties.probiotics have been used as alternative therapies in intestinal inflammatory disorders. many studies have shown that different bacterial probiotic strains possess immuno-modulatory and anti-inflammatory properties. however, there is an increasing interest in the use of non-viable bacteria to reduce the risk of microbial translocation and infection. the aim of this study was to evaluate whether the viability of l. fermentum cect5716 is essential to exert its intestinal anti-inflammatory effect. ...201525700085
long-term safety of early consumption of lactobacillus fermentum cect5716: a 3-year follow-up of a randomized controlled trial.lactobacillus fermentum cect5716 is a probiotic strain originally isolated from human breast milk. previous clinical studies in infants showed that the early administration of a milk formula containing this probiotic strain was safe and may be useful for the prevention of community-acquired infections. this is a 3-year follow-up study aimed at evaluating the long-term effects produced by the early consumption of an infant formula supplemented with l. fermentum cect5716 (experimental group, eg) c ...201525697549
role of probiotic lactobacillus fermentum kkl1 in the preparation of a rice based fermented beverage.a dominant lactic acid bacteria, lactobacillus fermentum kkl1 was isolated from an indian rice based fermented beverage and its fermentative behavior on rice was evaluated. the isolate grown well in rice and decreased the ph, with an increase of total titratable acidity on account of high yield in lactic acid and acetic acid. the production of α-amylase and glucoamylase by the strain reached plateau on 1st and 2nd day of fermentation respectively. the accumulation of malto-oligosaccharides of di ...201525693452
relationships between the genome and some phenotypical properties of lactobacillus fermentum cect 5716, a probiotic strain isolated from human milk.lactobacillus fermentum cect 5716, isolated from human milk, has immunomodulatory, anti-inflammatory, and anti-infectious properties, as revealed by several in vitro and in vivo assays, which suggests a strong potential as a probiotic strain. in this work, some phenotypic properties of l. fermentum cect 5716 were evaluated, and the genetic basis for the obtained results was searched for in the strain genome. l. fermentum cect 5716 does not contain plasmids and showed neither bacteriocin nor biog ...201525661998
saccharomyces cerevisiae transcriptional reprograming due to bacterial contamination during industrial scale bioethanol production.the bioethanol production system used in brazil is based on the fermentation of sucrose from sugarcane feedstock by highly adapted strains of the yeast saccharomyces cerevisiae. bacterial contaminants present in the distillery environment often produce yeast-bacteria cellular co-aggregation particles that resemble yeast-yeast cell adhesion (flocculation). the formation of such particles is undesirable because it slows the fermentation kinetics and reduces the overall bioethanol yield.201525633848
children with atopic dermatitis show clinical improvement after lactobacillus exposure.the role of probiotics in the treatment of atopic dermatitis (ad) is not clearly established. further clinical trials with new probiotic formulations are warranted.201525600169
zebrafish gut colonization by mcherry-labelled lactic acid bacteria.a critical feature of probiotic microorganisms is their ability to colonize the intestine of the host. although the microbial potential to adhere to the human gut lumen has been investigated in in vitro models, there is still much to discover about their in vivo behaviour. zebrafish is a vertebrate model that is being widely used to investigate various biological processes shared with humans. in this work, we report on the use of the zebrafish model to investigate the in vivo colonization abilit ...201525586576
complete genome sequence of the probiotic lactobacillus fermentum f-6 isolated from raw milk.lactobacillus fermentum f-6 was isolated from raw milk in inner mongolia of china with desirable probiotic properties. the genome contains a circular 2.06mb chromosome and has no plasmid. further in silico analysis revealed its genetic basis for adhesion, exopolysaccharides production and citrate fermentation, which makes it a strain of high industrial potential.201525533399
safety and efficacy of human breast milk lactobacillus fermentum cect 5716. a mini-review of studies with infant formulae.human breast milk has been described as a source of lactic acid bacteria. lactobacillus fermentum cect5716 is a human breast milk strain whose probiotic properties, safety and efficacy has been demonstrated in vitro and in vivo, including controlled trials with human adults. since the origin of this probiotic strain is human breast milk, we aimed to investigate the safety and efficacy of an infant and a follow-on formulas supplemented with this strain of l. fermentum. we carried out two randomis ...201525519525
therapeutic effect of activated carbon-induced constipation mice with lactobacillus fermentum suo on treatment.the aim of this study was to investigate the effects of lactobacillus fermentum suo (lf-suo) on activated carbon-induced constipation in icr (institute of cancer research) mice. icr mice were orally administered with lactic acid bacteria for 9 days. body weight, diet intake, drinking amount, defecation status, gastrointestinal transit and defecation time, and the serum levels of mtl (motilin), gas (gastrin), et (endothelin), ss (somatostatin), ache (acetylcholinesterase), sp (substance p), vip ( ...201425464378
preventive effect of lactobacillus fermentum lee on activated carbon-induced constipation in mice.the aim of this study was to investigate the effects of lactobacillus fermentum lee (lf-lee) on activated carbon-induced constipation in icr mice. icr mice were orally administered lactic acid bacteria for nine days. body weight, dietary and water intake, defecation status, gastrointestinal (gi) transit and defecation time, as well as levels of motilin (mtl), gastrin (gas), endothelin (et), somatostatin (ss), acetylcholinesterase (ache), substance p (sp) and vasoactive intestinal peptide (vip) i ...201525452815
a constitutive unregulated expression of β-galactosidase in lactobacillus fermentum m1.a constitutively β-galactosidase (lacl)-producing lactobacillus fermentum m1 isolated from fermented milk was found to produce β-galactosidase in the presence of glucose. β-galactosidase activity produced in glucose (30 mm) medium was 2.17 u/ml as compared to 2.27 and 2.19 u/ml with galactose and lactose, respectively. when a combination of glucose (30 or 60 mm) with galactose (30 mm) was used as carbon source, β-galactosidase activity was not repressed rather was found increased when compared t ...201525319027
the use of maldi-tof mass spectrometry, ribotyping and phenotypic tests to identify lactic acid bacteria from fermented cereal foods in abidjan (côte d'ivoire).matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) protein analysis, automated ribotyping, and phenotypic tests (e.g., cell morphology, gas production from glucose, growth and acid production on homofermemtative-heterofermentative differential (hhd) agar medium, sugar fermentation patterns) were used to identify 23 lactic acid bacteria (lab) isolated from fermented cereal foods available in abidjan, côte d'ivoire. pediococcus acidilactici (56.5%), lactoba ...201425279017
probiotic characteristics of lactobacillus fermentum strains isolated from tulum cheese.the aim of this study was to characterize the probiotic characteristics of lactobacillus fermentum strains isolated from tulum cheese. seven l. fermentum strains were selected among the isolated and identified lactobacillus strains due to their abundance. when the gastric condition was considered, l. fermentum lp3 and lp4 were able to tolerate ph 2.5 and 1% bile salt. all l. fermentum strains had similar enzymatic activity and antibiotic resistance pattern but the highest antagonistic effect was ...201425270832
lactobacillus gorillae sp. nov., isolated from the faeces of captive and wild western lowland gorillas (gorilla gorilla gorilla).four strains of gram-staining-positive, anaerobic rods were isolated from the faeces of western lowland gorillas (gorilla gorilla gorilla). three strains, kz01(t), kz02 and kz03, were isolated at the kyoto city zoo, japan, and one strain, gg02, was isolated in the moukalaba-doudou national park, gabon. these strains were investigated taxonomically. these strains belonged to the lactobacillus reuteri phylogenetic group according to phylogenetic analysis based on 16s rrna gene sequences and specif ...201425240022
identification and characterization of bile salt hydrolase genes from the genome of lactobacillus fermentum mtcc 8711.lactobacillus fermentum is a lactic acid bacterium of probiotic importance, which is found ubiquitously in fermented milk products. bile salt hydrolase (bsh) has a significant role in affording probiotic properties to lactobacilli. in the present study, two bsh genes encoding bsh1 and bsh2 were identified from the draft genome sequence of l. fermentum mtcc 8711. nucleotide comparison revealed no significant similarity between bsh1 and bsh2 genes, whereas the deduced amino acid sequences showed 2 ...201425099376
fresh-cut pineapple as a new carrier of probiotic lactic acid bacteria.due to the increasing interest for healthy foods, the feasibility of using fresh-cut fruits to vehicle probiotic microorganisms is arising scientific interest. with this aim, the survival of probiotic lactic acid bacteria, belonging to lactobacillus plantarum and lactobacillus fermentum species, was monitored on artificially inoculated pineapple pieces throughout storage. the main nutritional, physicochemical, and sensorial parameters of minimally processed pineapples were monitored. finally, pr ...201425093163
bioinspired magneto-optical bacteria."two-in-one" magneto-optical bacteria have been produced using the probiotic lactobacillus fermentum for the first time. we took advantage of two features of bacteria to synthesize this novel and bifunctional nanostructure: their metal-reducing properties, to produce gold nanoparticles, and their capacity to incorporate iron oxide nanoparticles at their external surface. the magneto-optical bacteria survive the process and behave as a magnet at room temperature.201425068183
amelioration of colitis in mouse model by exploring antioxidative potentials of an indigenous probiotic strain of lactobacillus fermentum lf1.based on the preliminary screening of eight indigenous putative probiotic lactobacilli, lactobacillus fermentum lf1 was selected for assessing its antioxidative efficacy in dss colitis mouse model based on its ability to enhance the expression of "nrf2" by 6.43-fold and malondialdehyde (mda) inhibition by 78.1 ± 0.24% in ht-29 cells under h2o2 stress. the disease activity index and histological scores of lf1-treated mice were lower than the control group. however, expression of "nrf2" was not ob ...201425061603
investigation of probiotic bacteria as dental caries and periodontal disease biotherapeutics.oral diseases, specifically dental caries and periodontal disease, are characterised by increases in pathogenic microorganisms, increased demineralisation and increased inflammation and levels of inflammatory markers. despite the therapeutic strategies, oral diseases have elevated prevalence rates. recent work has demonstrated that probiotic bio-therapeutics can decrease oral pathogen counts, including caries-causing streptococcus mutans and oral inflammation. the aim of this work was to investi ...201425006013
antioxidative capacity of lactobacillus fermentum lf31 evaluated in vitro by oxygen radical absorbance capacity assay.the aim of this study was to evaluate the performance of the overall antioxidant of lactobacillus fermentum lf31 bacterium with prebiotic supplement in human colon cultured cells.201424985014
quantitative high-resolution melting pcr analysis for monitoring of fermentation microbiota in sourdough.current methods of monitoring the microbial ecology of food fermentation system are generally labor intensive and/or time consuming. this study developed two methods based on high-resolution melting curves (hrm) to monitor sourdough microbiota during fermentation and to investigate the effect of cereal substrate on microbial ecology. a strain cocktail of lactobacillus fermentum fua3165, lactobacillus plantarum fua3309, lactobacillus paracasei fua3166 and lactobacillus reuteri fua3168 was used to ...201424984221
probiotic abilities of riboflavin-overproducing lactobacillus strains: a novel promising application of probiotics.the probiotic potential of lactobacillus plantarum and lactobacillus fermentum strains, capable of overproducing riboflavin, was investigated. the riboflavin production was quantified in co-cultures of lactobacilli and human intestinal epithelial cells, and the riboflavin overproduction ability was confirmed. when milk and yogurt were used as carrier matrices, l. plantarum and l. fermentum strains displayed a significant ability to survive through simulated gastrointestinal transit. adhesion was ...201424903812
lactobacillus with probiotic potential from homemade cheese in azerbijan.lactobacillus is believed to be beneficial in human health, thus the search for isolation and identification of friendly human bacteria from traditional fermented foods is important in medicine. one of the dairy products, traditional cheese as a highly-consumed dairy product could be a valuable source of these friendly edible germs.201424790899
preventive effect of fermented maillard reaction products from milk proteins in cardiovascular health.the aim of this study was to determine the dual effect of maillard reaction and fermentation on the preventive cardiovascular effects of milk proteins. maillard reaction products (mrp) were prepared from the reaction between milk proteins, such as whey protein concentrates (wpc) and sodium caseinate (sc), and lactose. the hydrolysates of mrp were obtained from fermentation by lactic acid bacteria (lab; i.e., lactobacillus gasseri h10, l. gasseri h11, lactobacillus fermentum h4, and l. fermentum ...201424731635
screening of indigenous oxalate degrading lactic acid bacteria from human faeces and south indian fermented foods: assessment of probiotic potential.lactic acid bacteria (lab) have the potential to degrade intestinal oxalate and this is increasingly being studied as a promising probiotic solution to manage kidney stone disease. in this study, oxalate degrading lab were isolated from human faeces and south indian fermented foods, subsequently assessed for potential probiotic property in vitro and in vivo. based on preliminary characteristics, 251 out of 673 bacterial isolates were identified as lab. a total of 17 strains were found to degrade ...201424723820
the antibacterial and anti-biofouling performance of biogenic silver nanoparticles by lactobacillus fermentum.biofouling is a major challenge in the water industry and public health. silver nanoparticles (agnps) have excellent antimicrobial properties and are considered to be a promising anti-biofouling agent. a modified method was used to produce small sized and well-dispersed biogenic silver nanoparticles with a mean size of ~6 nm (bio-ag0-6) using lactobacillus fermentum. the morphology, size distribution, zeta potential and oxidation state of the silver were systematically characterized. determinati ...201424564796
viability and resistance of lactobacilli isolated from cocoa fermentation to simulated gastrointestinal digestive steps in soy yogurt.to study the potential probiotic characteristics such as decrease of ph, microbial viability, and tolerance to simulated digestive steps of fermented soy beverage ("soy yogurt") produced with lactobacilli isolated from cocoa fermentation (lactobacillus fermentum tcuesc01 and lactobacillus plantarum tcuesc02) during fermentation and refrigerated storage. the sensory acceptance of the yogurts was also tested. samples of soy yogurt produced with l. fermentum tcuesc01 or l. plantarum tcuesc02 were c ...201424547696
identification of lactobacillus plantarum, lactobacillus pentosus and lactobacillus fermentum from honey stomach of honeybee.this study aimed to isolate and identify lactobacillus in the honey stomach of honeybee apis dorsata. samples of honeybee were collected from a. dorsata colonies in different bee trees and lactobacillus bacteria isolated from honey stomachs. ninety two isolates were gram-stained and tested for catalase reaction. by using bacterial universal primers, the 16s rdna gene from dna of bacterial colonies amplified with polymerase chain reaction (pcr). forty-nine bacterial 16s rdna gene were sequenced a ...201324516438
evaluation of stress tolerance and fermentative behavior of indigenous saccharomyces cerevisiae.sixty six indigenous saccharomyces cerevisiae strains were evaluated in stressful conditions (temperature, osmolarity, sulphite and ethanol tolerance) and also ability to flocculate. eighteen strains showed tolerant characteristics to these stressful conditions, growing at 42 °c, in 0.04% sulphite, 1 mol l(-1) nacl and 12% ethanol. no flocculent characteristics were observed. these strains were evaluated according to their fermentative performance in sugar cane juice. the conversion factors of s ...201324516430
superoxide dismutase recombinant lactobacillus fermentum ameliorates intestinal oxidative stress through inhibiting nf-κb activation in a trinitrobenzene sulphonic acid-induced colitis mouse model.superoxide dismutase (sod) can prevent and cure inflammatory bowel diseases by decreasing the amount of reactive oxygen species. unfortunately, short half-life of sod in the gastrointestinal tract limited its application in the intestinal tract. this study aimed to investigate the treatment effects of recombinant sod lactobacillus fermentum in a colitis mouse model.201424484394
effect of two probiotic strains of lactobacillus on in vitro adherence of listeria monocytogenes, streptococcus agalactiae, and staphylococcus aureus to vaginal epithelial cells.the lactobacilli probiotics maintain a normal vaginal biota and prevent disease recurrence. this microorganisms form a pellicle on the vaginal epithelium that acts as a biologic barrier against colonization by pathogenic bacteria. in this paper were realized assays of exclusion, competition, and displacement. for these test, vaginal epithelial cells, two strains of lactobacilli and pathogenic bacteria (staphylococcus aureus, streptococcus agalactiae and listeria monocytogenes) were used. the lac ...201424469557
exopolysaccharides producing lactobacillus fermentum strain for enhancing rheological and sensory attributes of low-fat dahi.lactobacillus fermentum v10 was able to show large capsules surrounding the cell surface and produced 247.37 ± 0.76 mg/l polysaccharides in fermentation medium. the effect on technological properties of low-fat dahi found to be significantly (p < 0.01) improved for lactobacillus fermentum v10 than control dahi made by eps(+) lb. delbrueckii subsp. bulgaricus ncdc 285 and eps(-) lb. delbrueckii subsp. bulgaricus 09 cultures. low fat dahi prepared by exopolysaccharides producing lactobacillus ferm ...201324426040
evaluation of functional aspects of lactobacillus fermentum cfr 2195 isolated from breast fed healthy infants' fecal matter.functional properties of the lactobacillus fermentum cfr 2195, isolated from healthy infant feces have been evaluated. the adherence of l. fermentum to ht-29 and caco-2 cell-lines were found to be 197.66 ± 15.62 and 100.33 ± 15.69 per 100 cells, respectively. the effect of different concentrations of fos (0.5, 1.0, 1.5, 2.0 and 2.5%) on the growth rate of l. fermentum was checked and 2.0% fos was selected for further studies. the synbiotic preparation containing l. fermentum and fos exhibited si ...201324425928
riboflavin-overproducing strains of lactobacillus fermentum for riboflavin-enriched bread.lactobacillus fermentum isolated from sourdough was able to produce riboflavin. spontaneous roseoflavin-resistant mutants were obtained by exposing the wild strain (named l. fermentum pbcc11) to increasing concentrations of roseoflavin. fifteen spontaneous roseoflavin-resistant mutants were isolated, and the level of vitamin b₂ was quantified by hplc. seven mutant strains produced concentrations of vitamin b₂ higher than 1 mg l⁻¹. interestingly, three mutants were unable to overproduce riboflavi ...201424413973
oral administration of lactobacillus fermentum i5007 favors intestinal development and alters the intestinal microbiota in formula-fed piglets.the present study was conducted to evaluate the effects of early administration of lactobacillus fermentum i5007 on intestinal development and microbial composition in the gastrointestinal tract using a neonatal piglet model. full-term 4 day old piglets, fed with milk replacer, were divided into a control group (given placebo of 0.1% peptone water) and a l. fermentum i5007 group (dosed daily with 6 × 10(9) cfu/ml l. fermentum i5007). the experiment lasted 14 days. on day 14, a significant increa ...201424404892
the use of lactic acid bacteria starter culture in the production of nunu, a spontaneously fermented milk product in ghana.nunu, a spontaneously fermented yoghurt-like product, is produced and consumed in parts of west africa. a total of 373 predominant lactic acid bacteria (lab) previously isolated and identified from nunu product were assessed in vitro for their technological properties (acidification, exopolysaccharides production, lipolysis, proteolysis and antimicrobial activities). following the determination of technological properties, lactobacillus fermentum 22-16, lactobacillus plantarum 8-2, lactobacillus ...201426904646
draft genome sequence of lactobacillus fermentum strain 3872.this report describes a draft genome sequence of lactobacillus fermentum strain 3872. the data revealed remarkable similarity to and dissimilarity with the published genome sequences of other strains of the species. the absence of and variation in structures of some adhesins and the presence of an additional adhesin may reflect adaptation of the bacterium to different host systems and may contribute to specific properties of this strain as a new probiotic.201324285652
human oral isolate lactobacillus fermentum agr1487 reduces intestinal barrier integrity by increasing the turnover of microtubules in caco-2 cells.lactobacillus fermentum is found in fermented foods and thought to be harmless. in vivo and clinical studies indicate that some l. fermentum strains have beneficial properties, particularly for gastrointestinal health. however, l. fermentum agr1487 decreases trans-epithelial electrical resistance (teer), a measure of intestinal barrier integrity. the hypothesis was that l. fermentum agr1487 decreases the expression of intestinal cell tight junction genes and proteins, thereby reducing barrier in ...201324244356
draft genome sequence of lactobacillus fermentum lf1, an indian isolate of human gut origin.lactobacillus fermentum is a normal inhabitant of the human gastrointestinal tract. here, we report the draft genome sequence of an indian isolate of the probiotic strain l. fermentum lf1, isolated from the human gut.201324233584
homo- and heterofermentative lactobacilli differently affect sugarcane-based fuel ethanol fermentation.bacterial contamination during industrial yeast fermentation has serious economic consequences for fuel ethanol producers. in addition to deviating carbon away from ethanol formation, bacterial cells and their metabolites often have a detrimental effect on yeast fermentative performance. the bacterial contaminants are commonly lactic acid bacteria (lab), comprising both homo- and heterofermentative strains. we have studied the effects of these two different types of bacteria upon yeast fermentat ...201424198118
molecular identification of potential th1/th2 responses-modulating bacterial genes using suppression subtractive dna hybridization.we characterized the immunomodulating potential of a number of lactobacilli isolated from an african fermented food by co-incubation with peripheral blood mononuclear cells (pbmcs). two strains with different immune modulating properties were genetically compared by suppression subtractive hybridization (ssh).201424192538
effect of orally administered l. fermentum ncimb 5221 on markers of metabolic syndrome: an in vivo analysis using zdf rats.metabolic syndrome, encompassing type 2 diabetes mellitus and cardiovascular disease, is a growing health concern of industrialized countries. ferulic acid (fa) is a phenolic acid found in foods normally consumed by humans that has demonstrated antioxidant activity, cholesterol-lowering capabilities, and anti-tumorigenic properties. select probiotic bacteria, including lactobacillus fermentum ncimb 5221, produce fa due to intrinsic ferulic acid esterase activity. the aim of the present research ...201424121931
probiotic potential and safety properties of lactobacillus plantarum from slovak bryndza cheese.one hundred and twenty-five acid-resistant presumptive lactobacilli were isolated from slovak bryndza cheese and screened for their antimicrobial activity against eight bacterial pathogens using spot agar assay. out of twenty-six lactobacillus strains with strong inhibition activity, twenty were identified as lactobacillus plantarum and six as lactobacillus fermentum. the most active eleven l. plantarum isolates were further characterized in vitro for some probiotic and safety properties. only t ...201324093103
genome sequence of lactobacillus fermentum strain mtcc 8711, a probiotic bacterium isolated from yogurt.lactobacillus fermentum strain mtcc 8711 is a lactic acid bacterium isolated from yogurt. here, we describe the draft genome sequence and annotation of this strain. the 2,566,297-bp-long genome consisted of a single chromosome and seven plasmids. the genome contains 2,609 protein-coding and 74 rna genes.201324072868
in vitro antagonistic growth effects of lactobacillus fermentum and lactobacillus salivarius and their fermentative broth on periodontal pathogens.as lactobacilli possess an antagonistic growth property, these bacteria may be beneficial as bioprotective agents for infection control. however, whether the antagonistic growth effects are attributed to the lactobacilli themselves or their fermentative broth remains unclear. the antagonistic growth effects of lactobacillus salivarius and lactobacillus fermentum as well as their fermentative broth were thus tested using both disc agar diffusion test and broth dilution method, and their effects o ...201224031966
surface-associated muc5b mucins promote protease activity in lactobacillus fermentum biofilms.mucosal surfaces are coated with layers of mucus gel that protect the underlying tissues and promote colonization by members of the commensal microflora. lactobacillus fermentum is a common inhabitant of the oral cavity, gastrointestinal and reproductive tracts and is one of the most important lactic acid bacteria contributing to the formation of a healthy intestinal microflora. we have investigated the proteolytic activity in l. fermentum in response to interactions with the muc5b mucin, which ...201324010726
study of the physicochemical parameters and spontaneous fermentation during the traditional production of yakupa, an indigenous beverage produced by brazilian amerindians.yakupa is a traditional non-alcoholic cassava beverage produced by brazilian amerindians. in this work the microbial dynamics and metabolites involved in yakupa fermentation were investigated by pcr-denaturing gradient gel electrophoresis and chromatography analysis, respectively. the lactic acid bacteria (lab) population was higher than yeast in the beginning of fermentation (5 log cfu ml(-1) and 3 log cfu ml(-1), respectively) and after 36 h both population increased reaching 7 log cfu ml(-1), ...201423996637
a subchronic toxicity study on lactobacillus fermentum gm 090 in rat. 201323981555
[characterization of a probiotic lactobacillus strain isolated from oral cavity].from oral cavity we isolated and characterized probiotic lactobacilli that could probability be applied to therapy and prevention of oral diseases.201323858716
interaction of lactobacillus fermentum bghi14 with rat colonic mucosa: implications for colitis induction.the present study was carried out to test the colonic mucosal response of rats to oral supplementation with lactobacillus fermentum bghi14 and to correlate the tissue reaction to trinitrobenzenesulfonate (tnbs)-induced colitis with mucosal barrier alterations caused by bacterial ingestion. an immune cell-mediated reaction of healthy colonic tissue was noticed after bacterial feeding. after prolonged bacterial treatment, the observed reaction had retreated to normality, but the mrna levels of pro ...201323851097
lactobacillus fermentum, a pathogen in documented cholecystitis.lactobacillus species are probiotics proven to exhibit various preventative as well as therapeutic properties. while lactobacillus species have been implicated in the formation of dental caries, endocarditis and bacteremia, their role as pathogens in cholecystitis has not been reported. we present a rare case of lactobacillus fermentum working as a pathogen in cholecystitis.201323792476
expression of catalase in lactobacillus fermentum and evaluation of its anti-oxidative properties in a dextran sodium sulfate induced mouse colitis model.lactic acid bacteria are generally sensitive to hydrogen peroxide (h₂o₂). lactobacillus plantarum atcc14431 is one of the few lactic acid bacteria able to degrade h₂o₂ through the action of a manganese-dependent catalase (containing the kata gene). however, it is not a natural inhabitant of the intestinal tract and its bio-efficacy and survival in the gastrointestinal tract have never been tested. in this study, we successfully expressed the kata gene from l. plantarum atcc14431 in l. fermentum ...201323783813
novel probiotic dissolvable carboxymethyl cellulose films as oral health biotherapeutics: in vitro preparation and characterization.oral health is influenced by the mouth's resident microorganisms. dental caries and periodontitis are oral disorders caused by imbalances in the oral microbiota. probiotics have potential for the prevention and treatment of oral disorders. current formulations, including supplements and foods, have limitations for oral delivery including short storage time, low residence time in the mouth, effects on food consistency, and low patient compliance. oral thin films (otfs) may be efficient in deliver ...201323713443
structure determination of the exopolysaccharide of lactobacillus fermentum tds030603-a revision.the highly viscous neutral exopolysaccharide, produced in large amounts by lactobacillus fermentum tds030603 in mrs broth and in a chemically defined medium supplemented with glucose, was investigated by glc(-eims) monosaccharide and methylation analysis, periodate oxidation, maldi-tof mass spectrometry, and 1d/2d nmr spectroscopy. the glc(-eims) analyses showed that the eps contained d-glucose and d-galactose in an averaged molar ratio of 2.6:1.0, consisting of terminal d-glcp, 3-substituted d- ...201323680670
synbiotic administration of canine-derived strain lactobacillus fermentum ccm 7421 and inulin to healthy dogs.the canine-derived strain lactobacillus fermentum ccm 7421 has been demonstrated to exert certain health benefits as a probiotic in dogs. synbiotic combinations are widely used but are rarely studied in dogs. in this study the prebiotic inulin in combination with l. fermentum ccm 7421 was tested for its effects on faecal microbial populations, faecal characteristics, and blood biochemistry in canine experiments. healthy adult dogs (n = 36) were randomly assigned to 1 of 3 treatment groups (12 do ...201323647348
the effect of growth media and physical treatments on the adhesion properties of canine probiotics.the manufacturing processes have been reported to influence the properties of probiotics with potential impact on health properties. the aim was to investigate the effect of different growth media and inactivation methods on the properties of canine-originated probiotic bacteria alone and in combination mixture.201323617818
behavior of lactobacilli isolated from fermented slurry (ben-saalga) in gnotobiotic rats.most bacterial strains, which have been studied so far for their probiotic functions, are extensively used by manufacturers in developed countries. in our work, we sought to study a mix (called bsl) comprising three strains belonging to lactobacillus fermentum, l. paraplantarum and l. salivarius, that were isolated from a traditional african pearl millet based fermented slurry. our objective was to study this bsl cocktail in gnotobiotic rats, to evaluate their survival and their behavior in the ...201323577056
prevalence of streptococcus mutans and lactobacillus fermentum and their association with caries and dietary habits in preschool thai children.to detect the prevalence of streptococcus mutans and lactobacillus fermentum in plaque obtained from severe early childhood caries (s-ecc) and caries-free (cf) groups and to assess any association between their prevalence, feeding habits and oral hygiene practices within each group.201323576064
oral probiotic microcapsule formulation ameliorates non-alcoholic fatty liver disease in bio f1b golden syrian hamsters.the beneficial effect of a microencapsulated feruloyl esterase producing lactobacillus fermentum atcc 11976 formulation for use in non-alcoholic fatty liver disease (nafld) was investigated. for which bio f1b golden syrian hamsters were fed a methionine deficient/choline devoid diet to induce non-alcoholic fatty liver disease. results, for the first time, show significant clinical benefits in experimental animals. examination of lipids show that concentrations of hepatic free cholesterol, esteri ...201323554890
dietary supplementation with lactobacillus fermentum i5007 improves the anti-oxidative activity of weanling piglets challenged with diquat.to determine the effects of lactobacillus fermentum i5007 on the redox state of piglets oxidatively stressed with diquat.201323480628
probiotics and their effects on metabolic diseases: an update.probiotics are lactic acid bacteria which are used extensively in therapeutic preparations and added to foods. there are many studies which have demonstrated the effects of probiotics on metabolic diseases. one study has shown the effect of fermented dairy products on the serum cholesterol, especially with selected strains of lactic acid bacteria. it has been found that a minute quantity of the dry culture of lactobacillus fermentum kc4b, for example, can remove 14.8 mg of cholesterol from the c ...201323449881
incidence of bacteriocins produced by food-related lactic acid bacteria active towards oral pathogens.in the present study we investigated the incidence of bacteriocins produced by 236 lactic acid bacteria (lab) food isolates against pathogenic or opportunistic pathogenic oral bacteria. this set of lab contained several strains (≥17%) producing bacteriocins active against food-related bacteria. interestingly only streptococcus macedonicus aca-dc 198 was able to inhibit the growth of streptococcus oralis, streptococcus sanguinis and streptococcus gordonii, while lactobacillus fermentum aca-dc 179 ...201323443163
effects of probiotic-supplemented diets on growth performance and intestinal immune characteristics of broiler chickens.this study was conducted to investigate the effects of a probiotic product incorporating lactobacillus fermentum and saccharomyces cerevisiae on the growth performance and intestinal immune status in broiler chickens. a total of six hundred ninety-six 1-d-old male cobb broilers were randomly allotted by bw in 1 of 4 treatments for 6-wk trial. the dietary treatments included the basal diet (nc), and the basal diets supplemented with an antibiotic (100 mg of chlortetracycline/kg of diet; pc), 0.1% ...201323436517
green tea extract (camellia sinensis) fermented by lactobacillus fermentum attenuates alcohol-induced liver damage.here, the impact of an extract derived from green tea (camellia sinensis) and fermentation with lactobacilli fermentum strain ocs19 was explored with acute alcohol-induced liver damage. the study employed the hepg2 hepatic cell line and an in vivo murine model of liver damage. l. fermentum-fermented green tea extract (fgte) was found to possess pronounced alcohol metabolizing enzyme activity. it significantly enhanced the cell viability of hepg2 cells following of them exposure, to ethanol (p<0. ...201223221715
the probiotic bacterial strain lactobacillus fermentum d3 increases in vitro the bioavailability of ca, p, and zn in fermented goat milk.we determined calcium, magnesium, phosphorus and zinc levels in a total of 27 samples of commercial goat- and cow-milk fermented products and 9 samples of a goat-milk fermented product with addition of a probiotic bacterial strain, lactobacillus fermentum d3, manufactured experimentally by our research group. atomic absorption spectroscopy with flame atomization and uv/vis spectrophotometry were used as analytic techniques. the results of an in vitro digestion process showed that the bioavailabi ...201323179347
in vitro and in vivo assessment of cytochrome p450-mediated herb-drug interaction of ssang-hwa-tang.we have evaluated the herb-drug interaction potential of ssang-hwa-tang (sht) mediated by cytochrome p450 (cyp) inhibition/induction. further, the effects of fermentation on the cyp-mediated herb-drug interaction potential were determined. sht showed inhibitory activity toward cyp1a2, but not 2a6, 2b6, 2c9, 2c19, 2d6, 2e1, and 3a4 in human liver microsomes. the results of the enzyme kinetic study suggested that the sht-induced cyp1a2 inhibition is mixed reversible inhibition. the hepatic cyp exp ...201323122083
isolation of potential probiotic lactobacillus rhamnosus strains from traditional fermented mare milk produced in sumbawa island of indonesia.to explore potential probiotics in the traditional foods of indonesia, fermented mare milk produced in sumbawa island was investigated in this study. gram stain, catalase activity, gas production, cell morphology, carbohydrate utilization pattern, and 16s rdna sequencing were performed to identify isolated lactic acid bacteria. to assess their probiotic ability, tolerance of low ph, bile salts, artificial gastrointestinal fluids, and adhesion properties to extracellular matrices, were examined. ...201223047104
characterization of glucansucrase and dextran from weissella sp. tn610 with potential as safe food additives.pear-derived weissella sp. tn610 produced extracellular glycosyltransferase activity responsible for the synthesis of soluble exopolysaccharide from sucrose. acid and dextranase-catalyzed hydrolysis revealed that the synthesized polymer was a glucan. according to (1)h and (13)c nmr analysis, the glucan produced by tn610 was a linear dextran made of 96% α-(1→6) and 4% α-(1→3) linkages. zymogram analysis confirmed the presence of a unique glucansucrase of approximately 180 kda in the cell-free sup ...201323046923
synergistic impact of lactobacillus fermentum, lactobacillus plantarum and vincristine on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in mice.lactobacillus sp. is the most dominant probiotic strain of bacteria. evidence indicates that the consumption of lactobacillus sp. reduces the risk of colorectal cancer in animal models. the present study was carried out to determine whether administration of lactobacillus fermentum/ lactobacillus plantarum alone or in combination with vincristine have a synergistic impact on the control of colorectal cancer in an animal model. mice with 1,2 dimethylhydrazine (dmh) hydrochloride-induced colon can ...201222970015
design of a novel gut bacterial adhesion model for probiotic applications.a new gut bacterial adhesion model has been developed. for this, a continuous-flow bioreactor packed with bacteria-coated beads was designed to simulate the gut lining and other features. in vitro model efficacy shows successful bacterial cell gut adhesions: bacterial adhesion was higher with mucin-alginate compared to controls. in feasibility study, adhesion of lactobacillus fermentum ncimb 5221 and lactobacillus reuteri ncimb 701359 was investigated for their metabolic activities for bile salt ...201322889228
fermentation by amylolytic lactic acid bacteria and consequences for starch digestibility of plantain, breadfruit, and sweet potato flours.the potential of tropical starchy plants such as plantain (musa paradisiaca), breadfruit (artocarpus communis), and sweet potato (ipomoea batatas) for the development of new fermented foods was investigated by exploiting the capacity of some lactic acid bacteria to hydrolyze starch. the amylolytic lactic acid bacteria (alab) lactobacillus plantarum a6 and lactobacillus fermentum ogi e1 were able to change the consistency of thick sticky gelatinized slurries of these starchy fruits and tubers int ...201222860595
identification of lactic acid bacteria isolated during traditional fura processing in ghana.fura is a millet-based spontaneously fermented dumpling produced and consumed in parts of west africa, particularly nigeria, burkina faso and ghana. from eight traditional fura production sites in northern ghana, 862 lactic acid bacteria were isolated and identified to species level using a combination of genotypic and phenotypic methods including (gtg)(5)-based pcr fingerprinting and 16s rrna gene sequencing, multiplex pcr by means of reca gene sequence comparison, conventional morphological ch ...201222850376
phenotypic and genotypic characterization of thai oral streptococci, lactobacilli and pediococci.this work was to assess the isolation and identification of thai oral bacteria. seventeen viridans group streptococci (vgs) and seventeen lactic acid bacteria from saliva were characterization based on their morphological, physiological and biochemical characteristics and the 16s rna gene sequences analysis. the gram-positive cocci in chains of viridans group comprised of six isolates (group i) were identified as streptococcus gordonii, 6 isolates (group ii) were streptococcus salivarius, 4 isol ...201222735847
studies on the effects of probiotic lactobacillus mixture given orally on vaginal and rectal colonization and on parameters of vaginal health in women with intermediate vaginal flora.the vaginal microflora is composed of many bacterial species and plays a major role in maintaining the balance of this complex environment. this study was conducted in order to assess the degree and persistence of the colonization of vaginal epithelium by strains from an orally administered mixture of lactobacilli, containing lactobacillus fermentum 57a, lactobacillus plantarum 57b and lactobacillus gasseri 57c. we also monitored its effects on parameters of vaginal health, especially total lact ...201222721635
characterization and antioxidant property of probiotic and synbiotic yogurts.the effect of a prebiotic (fructooligosaccharides) or a synbiotic components (prebiotic and probiotic) on the viability, proteolysis and antioxidant properties of probiotic and synbiotic yogurt during 28 days of storage at 4 °c has been investigated. yogurt starters in conjunction with either probiotic bacteria lactobacillus plantarum cfr 2194, lactobacillus fermentum cfr 2192 and/or fructooligosaccharides (fos) were used for yogurt preparation. titratable acidity and ph of all yogurt samples fo ...201226781850
polyphasic approach for quantitative analysis of obligately heterofermentative lactobacillus species in cheese.obligately heterofermentative lactobacilli (ohl) present in cheese during ripening can influence the flavour and texture of the final product. in order to better evaluate, follow and control this population, there is a current need for easy-to-use tools. in this study, a culture-dependent quantitative method (abev medium) was set up for direct and selective enumeration of total ohl from cheese, and a culture-independent method based on specific real time pcr (qpcr) assays was developed to target ...201222608233
molecular characterization of lactic acid bacteria and in situ amylase expression during traditional fermentation of cereal foods.lactic acid bacteria play an important role in traditional fermented foods consumed in different countries. study of their taxonomic structure and diversity is necessary for starter culture selection, improved safety and nutritional enhancement. to achieve these objectives, microbial genomic typing methods were used to study genetic differences of autochthonous bacteria and their distribution in two traditional african fermented cereal foods. a total of 85 predominant bacterial species were isol ...201222608231
bioconversion of isoflavones and the probiotic properties of the electroporated parent and subsequent three subcultures of lactobacillus fermentum bt 8219 in biotin-soymilk.this study was aimed at an evaluation of the potential inheritance of electroporation effects on lactobacillus fermentum bt 8219 through to three subsequent subcultures, based on their growth, isoflavone bioconversion activities, and probiotic properties, in biotin-supplemented soymilk. electroporation was seen to cause cell death immediately after treatment, followed by higher growth than the control during fermentation in biotin-soymilk (p<0.05). this was associated with enhanced intracellular ...201222580314
effectivity of freeze-dried form of lactobacillus fermentum ad1-ccm7421 in dogs.the impact of probiotic supplementation of canine-derived strain lactobacillus fermentum ad1-ccm7421 in freeze-dried form on quantitative composition of microbiota and short-chain fatty acid profile in feces of dogs was demonstrated by two independent studies (straightforward repeated-measures model; study i: a dose of 2 g per dog for 2 weeks, 10(8) cfu/g, n = 12; study ii: 1 g per dog for 1 week, 10(7) cfu/g, n = 11. the results revealed a significant increase of lactic acid bacteria population ...201222547329
antifungal activity of two lactobacillus strains with potential probiotic properties.aflatoxin (highly toxic and carcinogenic secondary metabolites produced by fungi) contamination is a serious problem worldwide. modern agriculture and animal production systems need to use high-quality and mycotoxin-free feedstuffs. the use of microorganisms to preserve food has gained importance in recent years due to the demand for reduced use of chemical preservatives by consumers. lactic acid bacteria are known to produce various antimicrobial compounds that are considered to be important in ...201222497448
effect of co-inoculation of saccharomyces cerevisiae and lactobacillus fermentum on the quality of the distilled sugar cane beverage cachaça.the effect of lactobacillus fermentum in co-inoculation with saccharomyces cerevisiae ufla ca11 on the quality of cachaça (sugar cane spirit) was evaluated. the co-inoculation was first evaluated in flask fermentation, and subsequently, yeast and bacteria were co-cultured at approximately 10(5) cfu/ml and 10(8) cfu/ml, respectively, in 4 consecutive batches. l. fermentum did not affect the growth or activity (sugar consumption and fermentation rate) of s. cerevisiae ufla ca11 during fermentation ...201622416693
effects of ultrasound on growth, bioconversion of isoflavones and probiotic properties of parent and subsequent passages of lactobacillus fermentum bt 8633 in biotin-supplemented soymilk.this study aimed to evaluate the effects of ultrasound on lactobacillus fermentum bt 8633 in parent and subsequent passages based on their growth and isoflavone bioconversion activities in biotin-supplemented soymilk. the treated cells were also assessed for impact of ultrasound on probiotic properties. the growth of ultrasonicated parent cells increased (p<0.05) by 3.23-9.14% compared to that of the control during fermentation in biotin-soymilk. this was also associated with enhanced intracellu ...201222305107
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