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implications of clostridium septicum in vascular surgery: a case report and outcomes literature review.clostridium septicum is a rare organism, accounting for approximately 1.3% of clostridial infections and is associated with synchronous colonic malignancy. this case report describes a patient successfully treated for a mycotic aortic aneurysm secondary to c. septicum bacteremia. subsequent evaluation confirmed a colonic malignancy, prompting early intervention. a systematic literature review revealing a rate of gastrointestinal malignancy in this patient population is 71%, and hematologic malig ...201728479472
a simple electroelution method for rapid protein purification: isolation and antibody production of alpha toxin from clostridium septicum.clostridium septicum produces a number of diseases in human and farm animals which, in most of the cases, are fatal without clinical intervention. alpha toxin is an important agent and the unique lethal virulent factor produced by clostridium septicum. this toxin is haemolytic, highly lethal and necrotizing activities but is being used as an antigen to develop animal vaccines. the aim of this study was to isolate the alpha toxin of clostridium septicum and produce highly specific antibodies agai ...201728652930
clostridium septicum aortitis with synchronous ascending colon and rectal adenocarcinoma.clostridium septicum (c. septicum) aortitis is a rare condition frequently associated with colon adenocarcinoma and carries a poor prognosis. we report the case of a 66-year-old man who presented with abdominal pain, blood in the stool, fever and chills. laboratory tests were significant for leukocytosis and microcytic anemia. abdominal imaging revealed a right colon mass and aortitis. colonoscopy confirmed the right colon mass and also discovered a rectal mass, both adenocarcinomas. treatment c ...201728655990
[clostridium septicum aortitis : case report and update on infectious aortitis].a case of clostridium septicum aortitis is reported. the patient did not present any colon tumor. she died in spite of surgery and i.v. antibiotics. to date c. septicum has been reported only in about 40 cases of infectious aortitis, a disease with unspecific clinical presentation and a high mortality rate. a high index of suspicion is warranted for an early diagnosis which can be made mainly by blood cultures and contrast-enhanced ct-scan. only starting without delay a treatment that combines a ...201628686395
fatal clostridium septicum multifocal myonecrosis in a previously healthy 25-year-old man: role of nsaids? 201728705640
spontaneous c. septicum gas gangrene: a literature review.as the infectious disease paradigm undergoes a subtle shift, unusual infections associated with malignancy and immunosuppression are being increasingly reported. spontaneous or non-traumatic clostridium septicum infection is one such unusual infection which has gained prominence. this article aims to understand the pathophysiology, clinical manifestations and current trends in diagnosing and treating this rare but deadly infection. to understand the multifactorial causation of this infection a r ...201728780428
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