Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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proteolysis and the selective destruction of amino acids by clostridium sporogenes and clostridium histolyticum. | 1929 | 16559359 | |
variability in morphological and biochemical properties of clostridium histolyticum (weinberg and seguin). | 1937 | 16560062 | |
some serological aspects of the s-r change in clostridium histolyticum. | 1937 | 16560063 | |
studies on the proteinase of clostridium histolyticum. | 1937 | 16746452 | |
proteinase secretion and growth of clostridium histolyticum. | 1938 | 16746798 | |
studies on the endo-enzymes, particularly the peptidases, of clostridium histolyticum. | 1938 | 16746799 | |
enzymic adaptation in clostridium histolyticum. | 1938 | 16746800 | |
the proteinases of clostridium histolyticum. | 1940 | 16747287 | |
the collagenase activity of culture filtrates of clostridium histolyticum. | 1947 | 20344283 | |
the activation mechanism and physicochemical properties of clostridium histolyticum proteinase. | 1948 | 18871209 | |
clostridium histolyticum infection. | 1949 | 18146655 | |
production, purification, and some properties of clostridium histolyticum collagenase. | 1950 | 15440885 | |
enzymes of clostridium welchii type a and clostridium histolyticum that disintegrate decalcified human tooth dentine. | 1950 | 14778940 | |
the alpha, beta and gamma antigens of clostridium histolyticum (weinberg & séguin, 1916). | 1950 | 14778941 | |
a cysteine-activated proteinase of clostridium histolyticum. | 1952 | 13000153 | |
the partial purification of the lethal toxin of clostridium histolyticum. | 1952 | 13006410 | |
a comparison of the lethal and hemolytic toxins of clostridium histolyticum. | 1952 | 13006411 | |
the serological identification of cultures of clostridium histolyticum as group iii of the proteolytic clostridia. | 1952 | 14888966 | |
the haemolysin of clostridium histolyticum. | 1953 | 13106224 | |
the activity of clostridium histolyticum proteinase on synthetic substrates. | 1953 | 13031635 | |
[studies on the properties of clostridium histolyticum and clostridium septicum antisera]. | 1953 | 13124941 | |
separation of proteolytic enzymes of clostridium histolyticum. | 1954 | 13223777 | |
[the proteolytic enzymes of clostridium histolyticum; influence of complexon iii and of calcium on the stability of two of these enzymes]. | 1955 | 13260245 | |
[ammonia production and toxicity of clostridium histolyticum cultured in a gelatinated medium]. | 1956 | 13363038 | |
pharmacologically-active polypeptide formed from blood globulin by a cysteine-activated protease from clostridium histolyticum. | 1956 | 13373851 | |
[not available]. | 1956 | 13395010 | |
exopeptidases of clostridium histolyticum. | 1957 | 13445228 | |
nutritional studies with clostridium histolyticum. | 1957 | 13462971 | |
[purification and chemical properties of anatoxin of clostridium histolyticum]. | 1957 | 13499480 | |
effects of clostridium histolyticum enzymes upon burned and unburned tissues in vitro. | 1958 | 13521674 | |
new proteolytic enzymes from clostridium histolyticum filtrates. | 1958 | 13525621 | |
serological evidence for a specific clostridium histolyticum gelatinase. | 1958 | 13525623 | |
clostridium histolyticum collagenase: its purification and properties. | 1958 | 13534676 | |
the cysteine-inactivated proteinase (alpha-antigen) of clostridium histolyticum. | 1958 | 13525622 | |
studies on the collagenases of clostridium histolyticum. | 1959 | 13661949 | |
the use of clostridium histolyticum enzymes in the treatment of experimental third degree burns. | 1959 | 13675991 | |
[studies on clostridium histolyticum anatoxins using zone electrophoresis and counter diffusion on agar]. | 1959 | 13636341 | |
[study of immunological phenomena by means of tissue culture. iv. cytopathogenic effects of clostridium histolyticum toxin]. | 1959 | 13658453 | |
[on proteins and their reduction products. xvi. on the specificity of collagenase from clostridium histolyticum and its application to the determination of the primary structure of collagen. (preliminary report)]. | 1959 | 14401656 | |
[on proteins and their decomposition products. 18. the hydrolysis of synthetic and natural substrates by collagenase from clostridium histolyticum]. | 1960 | 13714094 | |
[clostripain, a protease from clostridium histolyticum. 1. purification activation by thiols]. | 1960 | 13758027 | |
electron microscopic studies on ultrathin sections of spores of clostridium tetani and clostridium histolyticum, with special reference to sporulation and spore germination process. | 1960 | 13774854 | |
[clostripain, a protease from clostridium histolyticum. 2. specificity]. | 1960 | 13708985 | |
toxicity of enzymes from clostridium histolyticum. | 1960 | 14403502 | |
debridement of experimental burns with clostridium histolyticum h-4 enzymes. | 1960 | 14399293 | |
[research on the odors emitted by anaerobic bacteria. iii. clostridium histolyticum]. | 1961 | 13701340 | |
large scale purification of proteinases from clostridium histolyticum filtrates. | conklin, david a. (walter reed army institute of research, washington, d. c.), marion e. webster, patricia l. altieri, sanford berman, joseph p. lowenthal, and raymond b. gochenour. large scale purification of proteinases from clostridium histolyticum filtrates. j. bacteriol. 82:589-594. 1961.-a method for the large scale preparation and partial purification of clostridium histolyticum proteinases by fractional precipitation with ammonium sulfate is described. conditions for adequate separation ... | 1961 | 13880849 |
factors affecting the elaboration by clostridium histolyticum of proteinases capable of debriding third degree burn eschars on guinea pigs. | berman, sanford (walter reed army institute of research, washington, d. c.), joseph p. lowenthal, marion e. webster, patricia l. altieri, and raymond b. gochenour. factors affecting the elaboration by clostridium histolyticum of proteinases capable of debriding third degree burn eschars on guinea pigs. j. bacteriol. 82:582-588. 1961.-a comparison of three strains of clostridium histolyticum grown in two different media indicated that the h-4 strain produced the greatest yield of enzyme(s) capabl ... | 1961 | 13867979 |
[experimental inoculation of the chick embryo with clostridium histolyticum]. | 1961 | 13884989 | |
debridement of burns on various animal species by clostridium histolyticum proteinases. | 1962 | 13899369 | |
enzymatic debridement of third-degree burns on guinea pigs by clostridium histolyticum proteinases. | webster, marion e. (walter reed army institute of research, washington, d. c.), patricia l. altieri, david a. conklin, sanford berman, joseph p. lowenthal, and raymond b. gochenour. enzymatic debridement of third-degree burns on guinea pigs by clostridium histolyticum proteinases. j. bacteriol. 83:602-608. 1962.-an attempt has been made to correlate in vitro activities of clostridium histolyticum h-4 proteinases, as measured against azocasein, azocoll, gelatin, and collagen, with their ability t ... | 1962 | 14005493 |
the interactions between clostridium septicum and clostridium histolyticum toxins and antitoxins. | 1962 | 13983973 | |
[stability behavior of collagenase from clostridium histolyticum]. | 1963 | 13938916 | |
multiplicity of clostridium histolyticum collagenases. | 1964 | 14240635 | |
[toxinogenesis and sporulation in clostridium histolyticum]. | 1965 | 4954005 | |
antibody for collagenase from clostridium histolyticum. | 1965 | 4285539 | |
isolation and characterization of collagenases i and ii from clostridium histolyticum. | 1965 | 4285899 | |
toxigenicity of clostridium histolyticum. | nishida, shoki (kanazawa university, kanazawa, japan), and masaaki imaizumi. toxigenicity of clostridium histolyticum. j. bacteriol. 91:477-483. 1966.-from 234 soil samples, 21 strains of clostridium histolyticum of different levels of alpha-toxigenicity were isolated by a new method specially designed for the isolation of this species. the alpha-toxigenicity of freshly isolated strains and of stock strains was closely associated with the potentiality for sporulation, growth, and smooth-colony f ... | 1966 | 5935337 |
[an anaerobic bacteriophage active on clostridium histolyticum]. | 1966 | 5969256 | |
[composition of the gases produced by clostridium histolyticum cultured in a medium containing thioglycolate]. | 1966 | 4963926 | |
[observations of potentiation of toxins of clostridium perfringens and clostridium histolyticum]. | 1967 | 4308692 | |
[study of the bacteriophages of clostridium histolyticum strain p]. | 1967 | 6062796 | |
[cytologic study of sporulation in clostridium histolyticum. sporogenous strain and sporulation mutants]. | 1967 | 6065945 | |
the effects of clostridium histolyticum collagenase on amino sugar-containing compound-collagen complexes. | 1967 | 4175206 | |
[bacteriophages of clostridium histolyticum. isolation and lysotype]. | 1967 | 5607844 | |
complement-inactivating proteinase(s) from clostridium histolyticum. | a proteinase fraction inhibiting the hemolytic activity of guinea pig complement was obtained from supernatant fluids of clostridium histolyticum cultures and purified 150- to 350-fold by ammonium sulfate precipitation, sephadex g-75 gel filtration, and diethylaminoethyl cellulose chromatography. an assay was developed based on the inactivation of hemolytic complement. partially purified anticomplementary preparations were active against casein and were capable of "solubilizing" escherichia coli ... | 1968 | 5724966 |
characterization of a human serum inhibitor of clostridium histolyticum proteinase(s). | normal animal sera inhibit at least one clostridium histolyticum proteinase. an assay procedure based on immune hemolysis was developed for the estimation of this inhibition. this inhibitory activity occurs in various levels in the sera of different animal species. the highest titers have been obtained with rat sera. the inhibitory activity from human serum was isolated and purified 16- to 27-fold by sephadex g-200 gel filtration and diethylaminoethyl cellulose or hydroxylapatite chromatography. ... | 1968 | 5303620 |
hydrolysis at arginylproline in polypeptides by clostridiopeptidase b. | clostridiopeptidase b, a sulfhydryl protease from clostridium histolyticum, hydrolyzes the arginylproline bond in the synthetic polypeptide methionyllysyl-bradykinin. hydrolysis also occurs at a reduced rate at the lysylarginine bond, further delineating the environment necessary for the minor proteolysis seen with this enzyme at lysine residues. the specificity of clostridiopeptidase b differs from trypsin, which hydrolyzes this synthetic polypeptide only at the lysylarginine bond. | 1968 | 5677534 |
peptide substrates for a proteinase of clostridium histolyticum. | 1968 | 5722284 | |
[on an asporogenic mutant of clostridium histolyticum incapable of synthesizing dipicolinic acid]. | 1968 | 5661577 | |
the properties of molecular fragments obtained on treating calfskin collagen with collagenase from clostridium histolyticum. | 1968 | 4302777 | |
purification and partial characterization of collagenolytic enzymes from clostridium histolyticum. | 1968 | 4297964 | |
pseudocollagenase: a protease from clostridium histolyticum. | 1968 | 4297969 | |
[effect of clostridium histolyticum collagenase on hexa- and polypeptides]. | 1970 | 4319428 | |
elastolytic activities of clostridium histolyticum. | 1970 | 4998030 | |
purification by molecular sieve chromatography on polyacrylamide bio gel p-300 of clostridium histolyticum collagenase. | 1970 | 4322486 | |
clostridium histolyticum collagenase. ii. partial characterization. | 1972 | 4340512 | |
[the effect of actinomyces fradiae 119 proteinases, trypsin and clostridium histolyticum collagenase on insoluble collagen from the achilles tendon]. | 1973 | 4363287 | |
[the action of proteolytic enzymes of clostridium histolyticum and clostridium novyi on human plasma proteins]. | 1973 | 4147399 | |
isolation by affinity chromatography of neutral proteinase from clostridium histolyticum. | 1973 | 4348177 | |
a novel aminopeptidase from clostridium histolyticum. | 1973 | 4631895 | |
the interaction of alpha2-macroglobulin with proteinases. binding and inhibition of mammalian collagenases and other metal proteinases. | 1. experiments were performed to determine whether the specific collagenases and other metal proteinases are bound and inhibited by alpha(2)-macroglobulin, as are endopeptidases of other classes. 2. a specific collagenase from rabbit synovial cells was inhibited by human serum. the inhibition could be attributed entirely to alpha(2)-macroglobulin; alpha(1)-trypsin inhibitor was not inhibitory. alpha(2)-macroglobulin presaturated with trypsin or cathepsin b1 did not inhibit collagenase, and pretr ... | 1974 | 4374931 |
[composition of gases emitted by clostridium histolyticum cultivated on sodium thioglycolate media in a vaccuum, after alkalinisation of the medium at the end of culturing]. | 1974 | 4216432 | |
immunoenzymology of clostridium histolyticum collagenase. | 1974 | 4137716 | |
presence of collagenase from clostridium histolyticum in gingival sulcal debris of a primitive population. | 1974 | 4358563 | |
responses of clostridium botulinum type b and e progenitor toxins to some clostridial sulfhydryl-dependent proteases. | sulfhydryl-dependent proteases produced by clostridium botulinum types a, b, and f, clostridium histolyticum, clostridium sporogenes and clostridium perfringens activate preferentially type e over type b progenitor toxin but less efficiently than trypsin. the results explain why activable toxin is demonstrable in culture of a strongly proteolytic type b strain. | 1975 | 1104932 |
action of bacterial collagenase on ascaris cuticle collagen. | the collagen from the cuticle of ascaris lumbricoides was digested by clostridium histolyticum collagenase [ec 3.4.24.3] in the presence and absence of cacl2. about 1.2 mumoles of amino groups per mg collagen was liberated when the digestion was performed in the presence of 5 mm cacl2, whereas about 0.5 mumole of amino groups per mg collagen was liberated by digestion in the absence of cacl2. in contrast, cacl2 influenced the extent of hydrolysis of rat tail tendon collagen only slightly. the re ... | 1975 | 175053 |
rabbit corneal damage produced by pseudomonas aeruginosa infection. | gross, light microscopic, and electron microscopic examination of the rabbit corneal destruction produced by experimental pseudomonas aeruginosa infections revealed a combination of acute inflammation and liquefaction necrosis of the cornea. degeneration of the epithelial cells and the start of polymorphonuclear leukocyte infiltration of the cornea occurred initially. these changes were followed by loss of the epithelium, degeneration and loss of the keratocytes and endothelium, loss of the char ... | 1975 | 169202 |
the application of collagenase, purified by affintiy chromatography, to the isolation of insoluble elastin from bovine aorta. | clostridium histolyticum collagenase (clostridiopeptidase a, ec 3.4.4.16), purified by affinity chromatography, was applied to the isolation of insoluble elastin from bovine aorta. the extremely low level of n-terminal residues (1.6 mol per 10(6) g of protein) present in this preparation indicated the almost complete lack of hydrolytic damage caused by the isolation procedure. the amino acid profile of the aortic elastin was found to be almost identical to that of insoluble elastin prepared from ... | 1975 | 167862 |
collagenase production by achromobacter iophagus. | achromobacter iophagus produced collagenase (ec 3.4.24.3) when cultured aerobically in buffer containing 5% peptone. the bacterium is non-pathogenic and tests on rabbits indicated that the culture medium was atoxic. the collagenase, which hydrolyzed insoluble and soluble native collagen, was purified by (nh4)2 so4 precipitation, starch block electrophoresis, and gel filtration. it was shown to be serologically distinct from clostridium histolyticum collagenase and to have molecular weight and se ... | 1975 | 165833 |
application of affinity chromatography to the purification of collagenase for the isolation of insoluble elastin. | clostridium histolyticum collagenase (clostridiopeptidase a, ec 3.4.4.19) was purified by batchwise separation with deae-cellulose followed by affinity chromatography on a column of alkali-treated elastin. the n-terminal amino acid profile of elastin isolated from bovine ligamentum nuchae using this enzyme preparation was compared with that of a duplicate sample purified with a mixture of collagenase i and ii (yoshida, e, and noda, h. (1965) biochim. biopsys. acta 105, 562-574). an approx. three ... | 1975 | 164935 |
extracellular aminopeptidase from clostridium histolyticum. | 1976 | 13266 | |
an extracellular aminopeptidase from clostridium histolyticum. | an aminopeptidase was isolated from the culture filtrate of clostridium histolyticum and purified to homogeneity. absence of endopeptidase activity in the purified preparation was demonstrated. gel filtration on a calibrated column indicates an apparent molecular weight of 340000 for the native enzyme. gel electrophoresis of the denatured enzyme in the presence of dodecylsulfate in constant acrylamide concentration and in a concentration gradient, resulted in the appearance of a single component ... | 1976 | 4318 |
collagenase enzymes from clostridium: characterization of individual enzymes. | four collagenases have been purified to apparent homogeneity from extracts of clostridium histolyticum and partially characterized. the four purified enzymes are devoid of hydrolytic activity against casein and the synthetic substrate, benzolyarginine naphthylamide, but all retain activity against native collagen. the enzymes are initially spearated by isoelectric focusing where three of the enzymes show distinct isoelectric points: collagenase i = 5.50, collagenase ii = 5.65, and collagenases i ... | 1976 | 184822 |
haemorrhagic and inflammatory properties of collagenase from c. histolyticum. | collagenase from clostridium histolyticum induced haemorrhages when applied to the surface of dog lung; it exerted a similar effect on mouse lung when injected intrathoracically. injected into rat paws, bacterial collagenase induced haemorrhage and oedema. effects of collagenase were prevented by several procedures that inhibit collagenolytic activity (heating at various temperatures and incubation with metal-complexing agents such as edta, penicillamine and dithiothreitol). protein protease inh ... | 1976 | 184702 |
the effect of calcium chloride on the activity and inhibition of bacterial collagenase. | the enzymatic behavior and inhibition patterns of collagenase of clostridium histolyticum in the presence of 0.5 m and 3.4 mm cacl2 have been examined viscosimetrically. the more concentrated salt was found to enhance the rate of digestion of calfskin collagen when either measured viscosimetrically or colorimetrically by trinitrobenzenesulfonate. however, the rate of digestion of calfskin gelatin is unaffected by 0.5 m cacl2 as determined colorimetrically. calcium chloride also proved to have a ... | 1976 | 178615 |
consecutive use of omega-aminoalkylagaroses. resolution and purification of clostripain and collagenase from clostridium histolyticum. | 1976 | 178310 | |
chemical characterization and study of the autodigestion of pure collagenase from achromobacter iophagus. | only one collagenase (ec 3.4.24.3) is produced by the non-pathogenic achromobacter iophagus strain. the chromatography of the crude enzyme on de-32 cellulose followed by gel filtration on sephadex g-100 in the presence of 1 m sodium chloride led to the isolation of a homogeneous enzyme. its specific activity (1.642 mukat/mg) represents the highest value ever obtained for a bacterial collagenase. the amino acid composition of a. iophagus collagenase differs from that of clostridium histolyticum m ... | 1976 | 177067 |
cleavage of beta-casein by collagenases from achromobacter iophagus and clostridium histolyticum. | 1976 | 182537 | |
change in the stability of tendon collagen during ageing in the reptile, calotes versicolor. a brief note. | age related changes in the digestibility of tendon collagen of the garden lizard, calotes versicolor, were traced using type i collagenase from clostridium histolyticum. collagen from older lizards showed less susceptibility for collagenase digestion than the younger lizards suggesting increased number of cross-linkages comparable with mammals. | 1976 | 186668 |