Publications

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[penimepicycline: studies on its chemical structure, physico-chemical properties, bioassay and chemical assay]. 19694977336
comparative ultrastructure of selected aerobic spore-forming bacteria: a freeze-etching study. 19694979698
effect of bacteria on chemotaxis in the cellular slime molds.the effect of chemotactic substances, secreted by escherichia coli, on the cellular slime molds was studied by deposition of bacteria near myxamoebae populations. droplets of a bacterial suspension and a myxamoebae suspension were placed separately, at predetermined distances from each other, on a hydrophobic agar surface of low rigidity. myxamoebae remained confined inside the droplets, except when they were activated by the bacterial products. the sphere of attraction increased at higher bacte ...19694980065
[study of the type composition of levorin a. biological properties of components of levorin a complex]. 19694980132
[significance of deposit ratio and deposit amount in the examination of sterility. 1]. 19694980336
enzymatic lysis of vegetative cells of bacillus popilliae and other sporeformers. 19694981162
[antibacterial effect of gentamicin in the scope of routine antibiogramms]. 19694981208
[utilization of amino acids by some bacterial species and isolation of pipecolinic acid by use of these bacteria]. 19694981271
antibiotic msd-819. preparation and properties of biologically active derivatives. 19694981312
stdies on streptomycetes. lateriomycins a and b, new antitumor and antibacterial antibiotics produced by streptomyces griseoruber, strain no. 71070. 19694981382
requirement for coenzyme a in the phosphoroclastic reaction of anaerobic bacteria.various bacteria which degrade pyruvate by the phosphoroclastic reaction were examined with respect to the role of coenzyme a (coa) in this reaction. the strictly anaerobic bacteria, which cleave pyruvate by the phosphoroclastic reaction characteristic of clostridia, required catalytic levels of coa for the co(2)-pyruvate exchange and acetoin-forming portions of the phosphoroclastic reaction. these reactions were reversibly inhibited by the coa analogue, desulfo-coa. in contrast, using cell-free ...19694982893
bacteriologic studies on wasting disease induced by neonatal thymectomy. 19704983533
[streptothricin x--a new antibiotic of the streptothricin group obtained under specific conditions of biosynthesis]. 19694984361
a micromethod for determination of antibiotics in serum. 19694985044
antimicrobial polypeptide synthesized by mucor pusillus nrrl 2543. 19704985140
[complications after umbilical vein catheterization in the premature and newborn]. 19694985254
procedures for the assay of carbenicillin in body fluids.the assay of carbenicillin in clinical specimens is complicated by the fact that carbenicillin also contains a small amount of benzylpenicillin, thereby precluding the use of conventional penicillin assay organisms. this report gives details of a microbiological assay method involving the use of a strain of pseudomonas aeruginosa which is very sensitive to carbenicillin but insensitive to benzylpenicillin. the outline of a microassay method with this organism is presented, and a method for the a ...19704985430
comparative allostery of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthetase as a molecular basis for classification.the allosteric pattern of control for 3-deoxy-d-arabino-heptulosonate 7-phosphate (dahp) synthetase has previously been shown to be strongly conserved among the member species of a given genus in bacteria. the implications of this finding as a procedural tool of bacterial phylogeny were pursued by a study of two organisms, sporosarcina ureae and aeromonas formicans, the taxonomic positions of which have been historically controversial. s. ureae has characteristics of both bacillaceae and microco ...19704985590
bacterial hydrocarbons: occurrence, structure and metabolism. 19704985817
microbioassay of antimicrobial agents.a previously described agar-diffusion technique for microbioassay of antimicrobial agents has been modified to increase sensitivity of the technique and to extend the range of antimicrobial agents to which it is applicable. this microtechnique requires only 0.02 ml of an unknown test sample for assay, and is capable of measuring minute concentrations of antibiotics in buffer, serum, and urine. in some cases, up to a 20-fold increase in sensitivity is gained relative to other published standardiz ...19704986725
problems in the bio-assay of orally administered cephaloglycin in biological fluids and method for the detection of its metabolite, desacetylcephaloglycin. 19704987304
[the sensitivity of tubercle bacilli to rifampicin and determination of active drug serum level by means of vertical diffusion method]. 19704987944
[presence of polyphosphateglucokinase in bacteria]. 19684989012
reduction in peroxide values and monocarbonyls of oxidized methyl oleate by several microbial cultures. 19704990156
the effect of alkylation on the antimicrobial activities of 7-hydroxy- and 4-hydroxycoumarins. 19704991933
interaction between insecticides and soil. microbiological assay of sevin and meta-iso-systox using bacteria as test organisms. 19704991990
presence of antioxidant materials in bacteria. 19704992304
[experiments and clinical experience with cephalexin]. 19704992613
effect of apollo 11 lunar samples on terrestrial microorganisms. 19714993600
[the setting free of lixiviatable nitrogen from ureaform by microorganisms]. 19704993682
cephaloglycin and its biologically active metabolite desacetylcephaloglycin.chromatographic studies and microbiological assays show that, after oral administration, cephaloglycin is partially converted in man to a biologically active metabolite desacetylcephaloglycin. the antibacterial activity of this metabolite compared to that of cephaloglycin is equivalent against gram-positive organisms but is lower against gram-negative bacilli. successful therapy of urinary tract infections with cephaloglycin must be mainly attributed to the antibacterial activity of this metabol ...19714994901
naphthylamidases of sarcina lutea. 19714995373
isolation and identification of a new toxin, altenuene, from the fungus alternaria tenuis. 19714995517
inhibition of the plaquing efficiency of t4r+ bacteriophage by subtilisin.the mechanism by which the replicative cycle of t4r(+) phage is inhibited by certain nonhost bacterial systems was investigated. some bacillaceae, especially bacillus subtilis, decreased the plaquing efficiency of this virus more than 95% within 24 hr of exposure. sarcina lutea and micrococcus sp. both failed to cause any significant change in the infectivity of t4r(+) phage. preliminary investigations into the nature of the inhibitory substance(s) suggested that an extracellularly elicited prot ...19714995848
[drug containers as possible carriers of infection in hospital]. 19714997966
[synthesis of pyrolnitrin analogs. 3. preparation and antibacterial effects of substituted 1,2-diarylmaleimides]. 19714997987
[mapping of biochemical activities of microorganisms]. 19714998269
[a highly active antibiotic substance isolated from pseudomonas]. 19694998533
[distribution of barotolerant microorganisms in soils]. 19714998586
clinical uses and control of rifampicin and clindamycin. 19714999067
thermal lysis of bacterial membranes and its prevention by polyamines. 19714999070
streptomyces torulosus sp. n., an unusual knobby-spored taxon.several strains of a streptomycete with unusual spore wall ornamentation were isolated from iowa soils. they are further characterized by coiled chains of spores, gray aerial mycelium, melanin-like pigments, and the production of antibacterial and antifungal antibiotics. spore wall ornamentations, as seen with the transmission electron microscope, do not correspond with any of the four generally recognized categories of spore wall ornamentation-smooth, warty, spiny, or hairy-but seem to represen ...19714999522
[antibiotic hyperforin from hypericum perforatum l]. 19715000144
quantitative structure--activity relationships in leucomycin and lincomycin antibiotics. 19715000561
hexose-atp phosphotransferases: comparative aspects. ii. cross-reactivity of hexokinases from a variety of species with antisera to yeast hexokinase. 19715001183
[development of caulobacter in mixed cultures]. 19715002168
[production of the antibiotic lienomycin in a culture of diastato chromogenes var. lienomycini]. 19715002219
[international standardization of biological activity of tetracycline]. 19715002221
therapy of staphylococcal infections in monkeys. vii. comparison of cyclacillin and nafcillin.intravenous inoculation of a penicillin-resistant phage type 80/81 staphylococcus caused lethal infection in seven of eight untreated monkeys. daily intragastric administration of 50 mg/kg given in two equal morning and afternoon doses of cyclacillin and nafcillin was followed by mortalities of four of four and two of four monkeys, respectively. after 100 mg per kg per day, three of four and one of four monkeys receiving cyclacillin and nafcillin, respectively, died. thus, mortality in controls ...19715002313
the antimicrobial activity of citral. 19715002370
[anti-sarcina factor produced by some strains of enterobacteriaceae]. 19715002513
the "sensitivity" of resting and dividing cells. 19715002845
[anti-mycobacterial activity of rifampicin]. 19715003253
the "sensitivity" of resting and dividing cells. 19705003582
[adsorption of bacteria on glass, modified glass surfaces and polymer films]. 19715005572
how well do patients take oral penicillin? a collaborative study in private practice. 19675006583
dna base composition of extremely halophilic cocci. 19725028089
[infections of the eye. microbiology and therapeutic results using gentamycin]. 19725049623
mycotic aneurysm of ascending aorta due to sarcina lutea. 19725067891
[biosynthesis of primary aliphatic monoamines by amino acid-aldehyde transamination in sarcina lutea]. 19725081910
variation in fatty acid composition of sarcina flava membrane lipid with the age of the bacterial culture. 19715089327
[fine structure of methanosarcina]. 19715096613
[heterotrophic microflora of amu-dar'ya surface waters and their significance in the mineralization of organic matter]. 19715096617
mechanism of excretion of a bacterial proteinase: demonstration of two proteolytic enzymes produced by a sarcina strain (coccus p).a sarcina strain (coccus p) produces two proteolytic enzymes. one is found only extracellularly, is far more prevalent, and is actively excreted during exponential growth. it is the enzyme responsible for the known strong proteolytic activity of the cultures of this strain. a second protease is, however, produced which remains associated with the intact cells but is released by the protoplasts. the two enzymes appear unrelated in their derivation. calcium ions play an essential role in preventin ...19715107856
mechanism of excretion of a bacterial proteinase: factors controlling accumulation of the extracellular proteinase of a sarcina strain (coccus p).it has been known that the extracellular proteinase of coccus p is found only in cultures grown in the presence of ca(2+). it is now shown that this cation is required neither for synthesis, excretion, or activation of a zymogen nor as a prosthetic factor necessary for enzymatic activity. the only function of ca(2+) is to stabilize the active structure of the enzyme molecule, presumably by substituting for absence of s-s bridges. in the absence of ca(2+), the excreted proteinase undergoes rapid ...19715107857
documents of antibiotic assays.a new technique is described, in which a copy machine (rank-xerox) is used for instantaneous reproduction of biological assays.19715111302
microbiological assay of the beta-exotoxin of bacillus thuringiensis. 19715111847
sarcina ventriculi in human faeces. 19715116255
properties of tyramine oxidase from sarcina lutea: oxidation of sh groups and qualitative alteration in substrate and inhibitor specificity. 19715121610
experimental osteomyelitis. ii. therapeutic trials and measurement of antibiotic levels in bone. 19715127070
biogenesis of the l-n, -dimethylleucine residue of etamycin. 19715130176
growth and pigmentation of sarcina aurantiaca at various temperatures. 19715137680
dna base composition of gram-positive cocci. 19715146835
[the blood level of ampicillin and dicloxacillin alone or in association]. 19715149954
serum levels after administration of rifampicin. 19715150794
pharmacological study of rifampicin after repeated high dosage during intermittent combined therapy. i. variation of the rifampicin serum levels (947 determinations). 19715150797
chromatography of carotenoid pigments from sarcina lutea on sephadex lh-20. 19715159955
tylosin residue analyses in swine tissue. 19715162493
microbial transformation of antibiotics: phosphorylation of clindamycin by streptomyces coelicolor müller.addition of clindamycin to whole-cell cultures of streptomyces coelicolor müller resulted in the loss of in vitro activity against organisms sensitive to clindamycin. incubation of such culture filtrates with alkaline phosphatase generated a biologically active material identified as clindamycin. fermentation broths containing inactivated clindamycin yielded clindamycin 3-phosphate, the structure of which was established by physical-chemical and enzymatic studies. clindamycin was phosphorylated ...19715166238
measurement of three antibiotics (penicillin, cephalothin, and chloramphenicol) when present together in mixtures.benzylpenicillin, cephalothin, and chloramphenicol were measured individually and quantitatively when present together in mixtures at concentrations found in patients. the assay depended on the selective inactivation of two of the antibiotics, permitting the third to be assayed as if present alone. agar seeded with a chloramphenicol-resistant, penicillinase-negative staphylococcus aureus was used for a cylinder-plate assay of appropriately diluted fluid to determine the activity of either benzyl ...19685187067
utilization of glucose and lactic acid by salivary sediment. 19695257933
bacterial proliferation in platelet products stored at room temperature. transfusion-induced enterobacter sepsis. 19715283524
deoxyribonucleic acid base composition of some micrococci and sarcinae. 19665296848
[studies on the distribution of antibiotics in the body, distribution of chloramphenicol and its fate in the chicken]. 19685304358
composition of cell walls of some gram-negative cocci. 19655325433
[on the photosensitivity of bacteria]. 19655327040
fatty acid composition of bacterial membrane and wall lipids. 19665328938
the molar growth yields of a range of microorganisms. 19655331751
fine structure of sarcina maxima and sarcina ventriculi.the fine structure of sarcina maxima and s. ventriculi was studied by electron and phase-contrast microscopy. the two organisms differ mainly with respect to their cell surface. a thick cellulose layer present on the cell wall of s. ventriculi was not observed on the surface of s. maxima. carbon replication indicated that the outer surface of s. ventriculi is rough in contour, probably as the result of the fibrillar nature of the accumulated cellulose. the cytoplasm of both sarcinae contains inc ...19675335898
studies on depurination and alkylation of dna's of different base compositions. 19665337732
survival of bacteria on metal surfaces.survivor curves were determined for serratia marcescens, sarcina lutea, pasteurella tularensis, and p. pestis deposited from the airborne state onto metallic surfaces and subsequently stored at various humidities and temperatures. cells of all species tested remained alive longest in a dry atmosphere, except that cells of s. marcescens survived best in a saturated atmosphere. survival decreased most rapidly at the intermediate humidity level for three of the test organisms, yet p. tularensis die ...19665339359
microbial transformation of antibiotics. 3. conversion of clindamycin to 1'-demethylclindamycin and clindamycin sulfoxide by streptomyces species. 19695346041
studies on transglycosidation to vitamin b6 by microorganisms. i. formation of a new vitamin b6 derivative, pyridoxine glucoside, by sarcina lutea. 19695347448
studies on transglycosidation to vitamin b6 by microorganisms. ii. chemical structure of pyridoxine glucoside. 19695347450
studies on transglycosidation to vitamin b6 by microorganisms. 3. distribution of activity of pyridoxine glucoside formation in microorganisms. 19695347451
synthesis and bioactivity of lincomycin-7-monoesters. 19695349756
the effects of herbicides on soil microflora. ii. the effect of herbicides on enzymatic activity of the soil. 19695358099
studies on conformational changes in the dna structure induced by protonation: reversible and irreversible acid titrations and sedimentation measurments. 19695362526
numerical taxonomy of genera micrococcu cohn and sarcina goodsir. 19695362642
effect of light on malate oxidation by membranes of a carotenoidless mutant of sarcina lutea. 19695362669
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