Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| pcr amplification of alleles at the dis80 locus: comparison of a finnish and a north american caucasian population sample, and forensic casework evaluation. | allele and genotype frequencies for the highly polymorphic d1s80 locus were determined in a finnish population sample by using pcr followed by high-resolution page and silver staining, a procedure called the amplified-fragment-length polymorphism (amp-flp) technique. in 140 unrelated finnish individuals 15 alleles and 43 phenotypes were observed. the d1s80 locus demonstrated a heterozygosity of .77, and the power of discrimination was .92 in this sample representing a genetically isolated finnis ... | 1992 | 1347970 |
| effects on body temperature in mice differentiate between dopamine d2 receptor agonists with high and low efficacies. | the effects of different dopamine (da) d2 receptor agonists and the da d2 receptor antagonist, emonapride, on body temperature were studied in male mice. the aim of the study was to test whether da d2 receptor agonists ranging from full agonists to agonists with low efficacy could be differentiated by means of their effect on body temperature. talipexole induced a marked hypothermia (maximum decrease of 6.5 degrees c). apomorphine, quinelorane, (+)-4-propyl-9-hydroxy-naphtoxazine((+)-phno), and ... | 2006 | 1352251 |
| expression of her2/neu oncogene product p185 in correlation to clinicopathological and prognostic factors of gastric carcinoma. | the expression of the her2/neu gene product p185 was retrospectively analyzed in 58 patients with gastric carcinoma. the results were correlated to various clinicopathological and prognostic factors. positive membrane staining for p185 could be detected in 38% of the patients (22/58). membrane staining was significantly greater in well and moderately differentiated tumors of the intestinal type when compared with poorly differentiated lesions and carcinomas of the diffuse type (p less than 0.01) ... | 2006 | 1352299 |
| the spliceosome assembly pathway in mammalian extracts. | a mammalian splicing commitment complex was functionally defined by using a template commitment assay. this complex was partially purified and shown to be a required intermediate for complex a formation. the productive formation of this commitment complex required both splice sites and the polypyrimidine tract. u1 small nuclear ribonucleoprotein (snrnp) was the only spliceosomal u snrnp required for this formation. a protein factor, very likely u2af, is probably involved in the formation of the ... | 2005 | 1383687 |
| value of dundee coronary risk-disk. | 2006 | 1392968 | |
| midirs has set up the world's first computer midwifery data base. | 2006 | 1403180 | |
| the regulation of endopeptidase-24.11 expression on human osteoblast-like cells in culture. | 1992 | 1426566 | |
| long-term effects of exercise training and hyperalimentation in adult cystic fibrosis patients with severe pulmonary dysfunction. | 2006 | 1428393 | |
| design and inhibitory properties of synthetic bowman-birk loops. | a cyclic tridecapeptide based on the sequence of an anti-tryptic loop of a bowman-birk inhibitor was synthesized, and demonstrated to be active as an inhibitor of trypsin. molecular modeling of this sequence suggested an improved sequence which demonstrated an order of magnitude improvement in the inhibitory constant. | 2006 | 1446974 |
| importance of maintaining normal nasal function in the cleft palate patient. | the external nose is a structure that provides prominence to the face. the internal nose is a paired nasal cavity that extends from the face to the pharynx. turbinates are major structures within the lateral walls of the nose. they perform the major functions of the nose that include respiration, humidification, temperature regulation, and filtration of the inspired air. conditions that obstruct the nose interfere with its optimal function. these range from acute or chronic infection to enlarged ... | 2006 | 1450189 |
| different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions. | we reported previously that the lymphocyte-derived octamer transcription factor 2a (oct-2a or otf-2a) activated both natural immunoglobulin promoters and synthetic promoters which contain the 'octamer' site, but was unable by itself to stimulate transcription from a remote enhancer position. here we examine a larger set of transcription factors with respect to their proximal versus remote activation. since a transcription factor may contain more than one activation domain, we have chosen to stud ... | 2006 | 1464321 |
| chromosomal illegitimate recombination in mammalian cells is associated with intrinsically bent dna elements. | illegitimate recombination is the most frequent mechanism for chromosomal rearrangements in mammalian cells, yet little is known about this process. most of the studies to date have looked at the sequences present at illegitimate junctions. these revealed the presence of recurrent dna motifs, none of which was consistently found. we have undertaken to determine if intrinsic dna structures such as bent dna elements could be a major determinant in chromosomal illegitimate recombination. using a tw ... | 2006 | 1464328 |
| management strategies in tuberculous atlanto-axial dislocation. | tuberculous atlanto-axial dislocation is an uncommon disease. five of six patients with tuberculous atlanto-axial dislocation were successfully managed using different strategies. the advantages and disadvantages of these different protocols and their appropriateness in a particular clinical situation are discussed. | 2006 | 1472318 |
| wire-guided endoscope passage. | 1978 | 1473685 | |
| costs of pharmaceutical care: can the profession do anything? | to review some of the factors that influence the cost of pharmaceuticals and the delivery of pharmaceutical care as well as some possible measures for decreasing these costs. | 2006 | 1482817 |
| konno procedure for congenital aortic stenosis with a single coronary artery from the left coronary sinus. | a right coronary artery originating from the left coronary sinus and traversing anteriorly is thought to be one of the contraindications for a konno aortoventriculoplasty in congenital aortic stenosis because this procedure necessitates incision of the right ventricular outflow tract. the case of a 5-year-old girl with congenital aortic stenosis associated with a single coronary artery, successfully treated surgically by the konno procedure and right coronary artery reimplantation, is reported. ... | 2005 | 1482829 |
| the development of a virtual database to provide on-line access to a large archive of clinical data. | the archival database of the help hospital information system at lds hospital is too large to be stored on line. the archival data are important for clinical and research applications. demountable disk packs have been used to store the archival database. this method of storage has four significant disadvantages. a virtual database was developed to overcome the limitations of this data-management scheme. this virtual database enables the transparent use of appropriate low-cost network-based stora ... | 2006 | 1482943 |
| coordinated delivery of clinical care: the "re-integration" of the medical group practice. | this paper suggests that for medical knowledge to be effective, it must be reliably translated into a series of synchronized activities, both clinical and operational. the goal of medical information science must be not only to identify the best course of care, but also through the use of systems for the ordering, scheduling, and deployment of staff and resources to assure that the planned course of care is reliably and efficiently delivered in actual practice settings. we present a brief histor ... | 2006 | 1482950 |
| postoperative analgesia using a computerised infusion of alfentanil following aortic bifurcation graft surgery. | a psion microcomputer controlled infusion system for alfentanil was assessed for the provision of post-operative analgesia in 14 patients who had undergone aortic bifurcation graft surgery. the system employed a pharmacokinetic model working in real time to deliver any selected target plasma concentration of alfentanil. the alfentanil infusion system was used for a mean time of 39 hours and for 96% of this time, patients were scored as having no pain or only mild pain. severe pain was recorded f ... | 1972 | 1484271 |
| acquisition of icu data: concepts and demands. | as the issue of data overload is a problem in critical care today, it is of utmost importance to improve acquisition, storage, integration, and presentation of medical data, which appears only feasible with the help of bedside computers. the data originates from four major sources: (1) the bedside medical devices, (2) the local area network (lan) of the icu, (3) the hospital information system (his) and (4) manual input. all sources differ markedly in quality and quantity of data and in the dema ... | 1972 | 1484274 |
| [ectotoxin-forming pyogenic staphylococcus aureus (s. aureus) as a cause of toxic shock syndrome (tss) in man]. | basing considerations on an extremely carefully examined case of toxic shock syndrome (tss), an analysis of this phenomenon is presented from the clinical and forensic points of view. tss is often associated with the term "tampon disease" but in the meantime it has turned out that it may also arise as a non-menstrual disorder, caused by local infections, for example after surgical interventions. the inevitable symptoms include: fever, exanthema, desquamation on the palms of the hands and soles o ... | 1992 | 1489323 |
| [nursing--a woman's job!]. | 2006 | 1489626 | |
| mechanisms of flow-mediated signal transduction in endothelial cells: kinetics of atp surface concentrations. | intracellular free calcium ([ca2+]i) was measured in single cells of a confluent endothelial monolayer subjected to defined flow. flow medium containing adenosine triphosphate (atp) was used to study the influence of flow forces upon agonist-response coupling as mediated via the p2y-purinoceptor. [ca2+]i responses were highly sensitive to the fluid motion at the cell surface; consecutive small increases of flow stimulated large [ca2+]i transients with the levels returning to baseline at the new ... | 1992 | 1489886 |
| surgical decision analysis: esophagectomy/esophagogastrectomy with or without drainage? | decision analysis was used to compare three management strategies for patients undergoing esophagogastrectomy for carcinoma of the esophagus or gastric cardia: drain all patients with either pyloromyotomy or pyloroplasty, drain no patient, or perform a test that stratifies patients into high-risk and low-risk groups for development of gastric outlet obstruction and drain the high-risk group. results indicate that a "drain all" approach is appropriate in clinical settings where the risk of gastri ... | 2006 | 1540069 |
| peripartum cardiomyopathy with recovery in a patient with coincidental eisenmenger ventricular septal defect. | severe pulmonary vascular disease was found during pregnancy in a 31 year old woman with a large ventricular septal defect. three months after delivery peripartum cardiomyopathy with severe biventricular failure developed. this was a chance association. recovery of ventricular function was slow but was complete two years later. there was no advance in the pulmonary vascular disease. | 2005 | 1540442 |
| diagnosis of sickle cell disease in chronically transfused patients. | standard electrophoretic methods for the diagnosis of hemoglobinopathies are confounded in individuals chronically transfused. we present the accurate diagnosis of sickle cell disease in two such transfused patients by the application of polymerase chain reaction technology to analyze patient's hemoglobin beta-chain genes directly. | 1992 | 1550267 |
| a portuguese/brazilian study of expressed emotion. | expressed emotion is a measure of family interaction, widely used in studies around the world to predict relapse in severe psychiatric disorders. the instrument was originally developed in london. it depends on subtle vocal nuances emerging in the course of the camberwell family interview (cfi). the extent to which these can be picked up in different languages and different cultures is an interesting question. this paper presents the results of a study of ee from brazil. the two raters achieved ... | 2006 | 1557678 |
| an autopsy case of renal cell carcinoma associated with extensive peliosis hepatis. | an autopsy case of renal cell carcinoma with extensive peliosis hepatis is reported. the patient was a 34-year-old female, who had had a left nephrectomy for renal cell carcinoma but died of multiple metastases one year and 4 months after surgery, despite chemotherapy and interferon treatment. at autopsy, the liver was enlarged markedly with multiple metastatic nodules and the non-neoplastic hepatic parenchyma had a spongy appearance, due to diffusely scattered, blood-filled cystic lesions. hist ... | 2006 | 1557990 |
| modulation of venular microvessel permeability by calcium influx into endothelial cells. | it has been proposed that calcium ion influx into endothelial cells modulates the permeability of venular microvessels via a calcium-dependent contractile process. the results of recent investigations using permeabilized endothelial cell monolayers conform to this hypothesis by demonstrating a calcium-dependent interaction of endothelial actin and myosin during the retraction of adjacent endothelial cells exposed to inflammatory agents. little is known about the pathway for calcium influx into e ... | 1992 | 1563597 |
| electrophysiologic basis of dynamic extensor splinting. | the use of dynamic extension splinting in the rehabilitation of extensor tendon injuries is gaining interest because of its apparent ability to improve clinical results. with such splinting, the extensor musculature is theoretically quiescent during both active flexion and rubber band-mediated extension; the gliding produced thereby decreases adhesion formation. our initial intent was to perform electromyographic studies on volunteers in dynamic extension splinting to test this electrophysiologi ... | 2006 | 1564273 |
| search for the optimal treatment of ovarian cancer: heavy metals, "belly baths," and ... yew trees. | 2006 | 1569441 | |
| food composition tables and food composition analysis in east europe. | 2006 | 1589999 | |
| late onset familial hallervorden-spatz disease: mr findings in two sisters. | two sisters affected by late onset hallervorden-spatz disease are described. in both patients, mr showed rings of decreased signal intensity surrounding hyperintense areas that gave a target-like appearance to the globi pallidi, a finding that corresponds with the known pathologic lesions in the disease. mr reflects the metabolic and anatomic evaluation of this disease. | 2006 | 1595483 |
| cholelithiasis in patients treated with a very-low-calorie diet. | one hundred seventy-nine obese patients (mean body mass index = 36.3) were retrospectively evaluated for the development of cholelithiasis associated with the use of a 2530-kj/d (605-kcal) very-low-calorie diet (vlcd). nine percent of patients had preexisting gallstones and 11% of patients developed gallstones either during or within 6 mo of completing the diet. six percent had subsequent cholecystectomy. ursodeoxycholic acid administered to one patient resulted in spontaneous stone dissolution ... | 2006 | 1615894 |
| rubella. winter outbreak in the australian capital territory (act). | 2006 | 1622773 | |
| [cryptococcosis in aids patients: a study of 19 cases]. | we discuss 19 cases of infection due to cryptococcus neoformans diagnosed in 438 aids patients admitted to our center (4%). fourteen of them showed meningitis confirmed by culture of c. neoformans in csf. clinical features were rather unspecific and disorders in csf parameters were non striking. the diagnostic techniques performed with best results were culture of c. neoformans and antigen determination, especially in serum. survival probability at one year was 75%. treatment response was good. ... | 1992 | 1626090 |
| the rat mast cell antigen ad1 (homologue to human cd63 or melanoma antigen me491) is expressed in other cells in culture. | previously we reported that the mab ad1 recognized a heavily glycosylated 50- to 60-kda protein (ad1 ag) sterically close to the high-affinity ige receptor on rat basophilic leukemia (rbl-2h3) cells. the n-terminal amino acid sequence of the ad1 ag was nearly identical to that of human cd63 (melanoma-associated ag me491). in this study we cloned the cdna of ad1 ag from a rat basophilic leukemia 2h3 cdna library. an open reading frame of 238 amino acids was identified that contained the n-termina ... | 1992 | 1634775 |
| effects of norethisterone on pressor response to angiotensin ii in men. | we examined the effects of norethisterone and/or mestranol on the pressor response to angiotensin ii in 20 healthy men. | 2006 | 1635747 |
| stroke risk from alcohol consumption using different control groups. | our aim in this study was to investigate the relation between chronic alcohol consumption and stroke. | 2006 | 1636184 |
| recurrent or aggressive bladder cancer. indications for adjuvant intravesical therapy. | advances in understanding of the variables that adversely affect the prognosis of patients with superficial bladder cancer allow more accurate predictions of the aggressive biologic potential of tumors. intravesical therapy appears to be an effective and essential adjuvant in those patients with high-risk tumor variables. multiple risk factors related to the tumor, individual patient characteristics, and treatment modality must be evaluated. assignment of the relative importance of these risk fa ... | 2006 | 1636233 |
| [the human chorionic gonadotropin (hcg) receptor: a new class within the family of gtp protein coupled receptors. epitope mapping of receptor-bound agonistic and antagonistic forms of hcg]. | human chorionic gonadotropin (hcg) is a member of the glycoprotein hormone family. it is composed of an alpha and a beta subunit, the latter being closely homologous to that of human luteinizing hormone (hlh). hcg and hlh bind to the same receptor. the molecular mass of hcg is 38 kd, up to 30% of which is contributed by the carbohydrate moieties linked to each of the two subunits. structure-function relationship studies have indicated that both subunits interact with the receptor and that altoge ... | 1992 | 1636261 |
| [you can lose money when you get sick during the course]. | 2006 | 1636284 | |
| [counseling is a success--ann-christine starts a course on the climacteric now. interview by eva aldstedt]. | 2006 | 1636293 | |
| antagonism of the motor effects of cgrp and of capsaicin on the guinea pig ileum by human cgrp8-37. | 1992 | 1637118 | |
| expression and processing of the rooster protamine mrna. | in situ hybridization in immature and mature testis sections shows that the rooster protamine mrna is transcribed in the post-meiotic stages of spermatogenesis. two distinct populations of rooster protamine mrna are expressed as determined by northern blot analysis. since there are two copies of the chicken protamine gene per haploid genome, the question was raised of whether the two mrna populations correspond to the two different genes or was a result of differential mrna processing. the fact ... | 1991 | 1664677 |
| the dysmyelinating mouse mutations shiverer (shi) and myelin deficient (shimld). | shiverer (shi/shi) is an autosomal recessive mouse mutation that produces a shivering phenotype in affected mice. a shivering gait can be seen from a few weeks after birth until their early death, which occurs between 50 and 100 days. the central nervous system of the mutant mouse is hypomyelinated but the peripheral nervous system appears normal. the myelin of the cns, wherever present, is not well compacted and lacks the major dense line. myelin basic protein (mbp), which is associated with th ... | 1990 | 1693848 |
| human prolactin gene expression. the use of an alternative noncoding exon in decidua and the im-9-p3 lymphoblast cell line. | the prolactin (prl) gene is normally expressed in the anterior pituitary lactotrope and the decidualized stromal cell of the human endometrium. we have recently described the ectopic expression of the human prl gene in a b-lymphoblastoid cell line, im-9-p. the im-9-p and decidual prl mrnas are approximately 150 nucleotides longer than the pituitary transcript. the protein coding sequence of the im-9-p and decidual prl cdnas is identical to the pituitary prl message, and the 3'-untranslated regio ... | 1990 | 1697858 |
| human prolactin gene expression. the use of an alternative noncoding exon in decidua and the im-9-p3 lymphoblast cell line. | the prolactin (prl) gene is normally expressed in the anterior pituitary lactotrope and the decidualized stromal cell of the human endometrium. we have recently described the ectopic expression of the human prl gene in a b-lymphoblastoid cell line, im-9-p. the im-9-p and decidual prl mrnas are approximately 150 nucleotides longer than the pituitary transcript. the protein coding sequence of the im-9-p and decidual prl cdnas is identical to the pituitary prl message, and the 3'-untranslated regio ... | 1990 | 1697858 |
| cyclic amp-induced slow inward current: its synaptic manifestation in aplysia neurons. | three presynaptic neurons, monosynaptically connected to the medial cells of the pleural ganglion of aplysia californica and previously shown to elicit camp-mediated diminutions in k conductance in those cells (kehoe, 1985a, b), were shown to elicit still another slow synaptic current that resembles the camp-induced cationic current described in the preceding paper (kehoe, 1990). the synaptic current elicited by these so-called "blocking" neurons was compared, in hyperpolarized medial cells, wit ... | 2006 | 1698941 |
| laryngectomy: the patient's view. | the disabilities following laryngectomy are well recognized. the incidence of these disabilities and the acceptability of the surgery to the patients were assessed by a questionnaire method. sixty-five patients participated in the study. the incidence of disabilities are discussed. total laryngectomy was felt to be a worthwhile operation by most of the patients in the study despite the disabilities they experienced afterwards. | 2006 | 1761948 |
| growth hormone prevents steroid-induced growth depression in health and uremia. | treatment with supraphysiological doses of corticosteroids results in protein wasting and impairment of growth, whereas exogenous growth hormone (gh) causes anabolism and improvement of growth. we wanted to know whether the growth depressing effects of methylprednisolone (mp) are more expressed in an organism which is chronically diseased and whether these effects can be counterbalanced by concomitant treatment with recombinant human growth hormone (rhgh). mp in doses from 1 to 9 mg/kg/day cause ... | 1991 | 1762304 |
| the effect of age on motor neurone death following axotomy in the mouse. | the ability of mouse motor neurones to survive axotomy during the first month of life was studied. the motor neurones that lie in the dorsolateral columns of spinal segments c7 and c8 and supply the flexor muscles of the forepaw were axotomized by cutting and removing part of the median and ulnar nerves above the elbow. the number and position of cell bodies with axons in these nerves were confirmed by retrograde labelling of the cut axons with horseradish peroxidase. the ability of these neuron ... | 1991 | 1769343 |
| cyclic changes in amphibian egg microvilli occur during the division cycle: implication of mpf. | the microvilli (mv) of pleurodeles (amphibian) eggs were examined following fertilization and compared with those of artificially activated eggs and enucleated eggs using scanning and transmission electron microscopy. the mv pattern in fertilized eggs was found to undergo a cyclic transformation during the course of the first few division cycles. similar changes also occurred in the mv of artificially activated eggs and enucleated eggs. the reorganization of the mv was sensitive to cycloheximide ... | 2006 | 1769344 |
| injury severity: better data through direct physician entry of anatomic injuries? | the authors compared the injury diagnoses and injury severity scores (isss) generated by three data-collection and -coding methods, and examined the times needed and costs associated with the methods. one method involved direct electronic entry of injury data by a physician in the admitting area. codes, severity scores, and times and costs varied significantly with the different methods, thus suggesting a need for further study of the derivation of injury severity codes. | 2007 | 1770847 |
| immobilisation of enzymes to nylon film. | 2007 | 1783118 | |
| non-adrenergic, non-cholinergic neural activation stabilizes smooth-muscle tone independently of eicosanoid factors in guinea-pig isolated airways. | 1. we examined the effect of variations in resting smooth-muscle tone induced eicosanoid inhibitors on the direction and magnitude of the non-adrenergic, non-cholinergic (nanc) nervous response in guinea-pig isolated airways. 2. nanc responses (in the presence of 1 microm atropine, 10 microm guanethidine) to electrical field stimulation (1200 ma; 0.5 ms; 240 s; 3 hz) were studied in guinea-pig isolated airway preparations (n = 4-7) taken from the proximal trachea, the distal trachea and the main ... | 1991 | 1797314 |
| non-adrenergic, non-cholinergic neural activation stabilizes smooth-muscle tone independently of eicosanoid factors in guinea-pig isolated airways. | 1. we examined the effect of variations in resting smooth-muscle tone induced eicosanoid inhibitors on the direction and magnitude of the non-adrenergic, non-cholinergic (nanc) nervous response in guinea-pig isolated airways. 2. nanc responses (in the presence of 1 microm atropine, 10 microm guanethidine) to electrical field stimulation (1200 ma; 0.5 ms; 240 s; 3 hz) were studied in guinea-pig isolated airway preparations (n = 4-7) taken from the proximal trachea, the distal trachea and the main ... | 1991 | 1797314 |
| [comparative study of culture media for isolating brucella ovis]. | for the isolation of brucella ovis, modified thayer-martin medium with the addition of 0.01 micrograms/ml of trimethoprim and 100 iu of nystatin (tmm) was compared with skirrow agar (sk). using viable counting technique, 11 strains were evaluated and the results were compared with those using columbia base agar with bovine blood 7% (cba). ninety-four semen samples of 33 rams from a flock with infection antecedents were cultured on the same media. growth of brucella ovis strains was similar in al ... | 1991 | 1815277 |
| biting behavior of anopheles mosquitoes in costa marques, rondonia, brazil. | mosquito collections were made in and near costa marques, rondonia, brazil, to determine anopheline anthropophilic/zoophilic behavior. collections from a non-illuminated, bovine-baited trap and indoor and outdoor human-bait collections were compared. anopheles darlingi and anopheles deaneorum were more anthropophilic than the other anophelines collected. the remainder of the anopheles species were collected much more frequently in bovine-baited traps than in human-bait collections. anopheles dar ... | 1991 | 1815282 |
| albumin excretion rate is not increased in atherosclerotic patients with peripheral vascular disease. | in type i diabetic patients, microalbuminuria is considered predictive of nephropathy and has been found associated with an increased mobility and mortality for atherosclerosis. an association between microalbuminuria and atherosclerosis has been reported in non diabetic atherosclerotic patients with hypertension. the aim of this study is to evaluate whether albumin excretion rate (aer) is increased in a selected group of normotensive patients with documented peripheral atherosclerotic disease. ... | 2007 | 1821046 |
| isoproterenol selectively releases endogenous and [14c]-labelled taurine from a single cytosolic compartment in astroglial cells. | taurine is stored in and released from astroglial cells. we have investigated whether taurine is stored in multiple subcellular compartments and whether taurine is released from a distinct pool. taurine compartmentation was examined by determining the subcellular distribution of labelled taurine and by comparing the specific radioactivities of taurine in cells with that of the taurine released into the superfusion medium during receptor stimulation. three observations indicate that taurine is fo ... | 2007 | 1828789 |
| oral administration of ssg, a beta-glucan obtained from sclerotinia sclerotiorum, affects the function of peyer's patch cells. | the effect of orally administered ssg, a beta-1,3-glucan obtained from the culture filtrate of a fungus, sclerotinia sclerotiorum ifo 9395, on the function of peyer's patch (pp) cells was investigated in comparison with that on spleen cells in mice. oral administration of ssg enhanced the proliferative response of pp cells to a t-cell mitogen, concanavalin a (con a), and a b-cell mitogen, lipopolysaccharide (lps), although the response of spleen cells was not affected. peyer's patch cells taken ... | 1991 | 1828793 |
| interaction of guanylic acid with the mg(ii), ca(ii), sr(ii), and ba(ii) ions in the crystalline solid and aqueous solution: evidence for the ribose c2'-endo/anti and c3'-endo/anti conformational changes. | the interaction of guanosine-5'-monophosphoric acid (h2-gmp) with the alkaline earth metal ions has been studied in aqueous solution at neutral ph. the crystalline salts of the type mg-gmp.5h2o, ca-gmp.6h2o, sr-gmp.7h2o, and ba-gmp.7h2o were isolated and characterized by fourier transform ir, 1h-nmr and x-ray powder diffraction measurements. two types of macrochelate complexes have been identified: (a) the direct metalbase and indirect metal-phosphate bindings (inner and outer sphere interaction ... | 2007 | 1851044 |
| miniature manipulator with microelectrode for chronic recording of single units from freely-moving animals. | we report a simple recording and stimulating system, a miniature manipulator with a microelectrode (mmm) that can be mounted on animal's skull. the system consists of a miniature manipulator and a microelectrode which are used in one body. several mmms can be implanted simultaneously into the brain as the part of the manipulator is small. with this device, recording of single units from several different cortices is possible from awake and unrestricted animals. | 1991 | 1851979 |
| clinical validation of a second-generation fructosamine assay. | the serum fructosamine assay, used to monitor short-term clinical glycemic control, reportedly has several technical drawbacks. however, technical improvements have resulted in a new second-generation assay of fructosamine. we evaluated this second-generation assay (from roche diagnostics) in 529 nondiabetic and diabetic patients and found a highly significant correlation with results of the first-generation assay (r = 0.91, p less than 0.001). use of the second-generation assay with samples fro ... | 2007 | 1855298 |
| plasminogen polymorphism in libyans: description of a new rare variant. | the genetic polymorphism of human plasminogen (plg) was investigated in libyans using wide-scale ultrathin-layer polyacrylamide isoelectric focusing with subsequent immunoblotting. the 2 common alleles, plg*a and plg*b, and 4 previously reported rare ones, plg*a3, plg*m4, plg*b1 and plg*b2, were observed. in addition, a new intermediate rare allele designated plg*mtripoli (plg*mt) was encountered. the estimated allele frequencies for the genes plg*a, plg*b, plg*a3, plg*mt, plg*m4, plg*b1 and plg ... | 1991 | 1855784 |
| major histocompatibility complex (mhc) class ii region in humans. | 2007 | 1855818 | |
| relevance of n-nitrosamines to oesophageal cancer in china. | oesophageal cancer occurs at a very high frequency in certain areas of china, especially in linxian county, henan province. previous studies suggested that n-nitroso compounds play a causative role. in order to study further the exposure of linxian inhabitants, the intake of n-nitrosamines in the diet was determined. the total daily intake of volatile nitrosamines and of n-nitroso-n-methylbenzylamine (nmbza) was higher in linxian than in two other counties. nmbza can induce cancer in animal and ... | 1991 | 1855832 |
| effects of long-term inhalation of n-nitrosodimethylamine in rats. | the toxicological evaluation and histopathological findings of a long-term inhalation study in progress with n-nitrosodimethylamine (ndma) are presented. exposure was to three concentrations of ndma: 0.04, 0.2 and 1.0 ppm (corresponding to 120, 600 and 3000 micrograms/m3). a significant reduction in median survival time (nine months) was seen in animals treated with the highest concentration of ndma. tumours occurred mainly in the nasal cavity, with the highest incidences in the groups receiving ... | 1991 | 1855872 |
| assessment of congenital hip dislocation with real-time ultrasound: a pictorial essay. | real-time ultrasound (us) is the imaging method of choice for diagnosis and follow-up of congenital dislocation of the infant hip (cdh). clinical aspects and the role of imaging are reviewed. technique and anatomy, both normal and abnormal, are illustrated, as well as, the use of sonography during treatment with pavlik harness and spica cast. correlation of ultrasound findings with clinical examination, other available imaging studies and long-term patient follow-up shows 100% sensitivity and 10 ... | 2007 | 1913315 |
| the case of a reluctant mule. | 2007 | 1913381 | |
| aerosol ventilation scintigraphy in the evaluation of bronchopleural fistula: a case report and literature review. | radioaerosol scanning is simple to perform and is widely used in conjunction with perfusion imaging to detect pulmonary emboli. it may also be a valuable tool for the early diagnosis of postpneumonectomy bronchopleural fistula. the authors present an illustrative case in which radioactive aerosol imaging was used to confirm a bronchopleural fistula secondary to pneumonectomy for squamous cell carcinoma. | 2007 | 1913391 |
| prognostic value of rhesus blood groups in oral squamous cell carcinomas. | in the current study of the prognosis of all patients (n equals 70) with squamous cell carcinomas (scc) of floor of mouth in norway during the period 1963 to 1972, the authors found that patients with rhesus (rh) (d)-negative blood group had significantly poorer prognosis (mean 5-year survival, 8%) than patients with rh (d)-positive blood group (5-year survival, 30%) (p equals 0.04). this extends the authors' previous observations in another group of oral cancer patients. the authors do not know ... | 1991 | 1913459 |
| treatment of malignant leydig cell tumor. | malignant leydig cell tumors (lct) are rare. only 32 cases of malignant lct (as evidenced by metastatic spread) were reported. generally metastatic spread occurs within 2 years of the primary lct, and the patient dies within 2 years of the discovery of metastatic disease. the tumor is highly resistant to both radiation and chemotherapy. it also has a great propensity for recurring after surgical resection. a case is reported of a patient whose metastatic disease occurred 8 years after his primar ... | 2007 | 1913469 |
| relationship between severity and clinical importance of symptoms in osteoarthritis. | seventeen patients with primary osteoarthritis of the knee were evaluated with respect to the severity and clinical importance of pain, stiffness and physical function during the conduct of a double-blind randomized controlled trial of flurbiprofen sr versus diclofenac sodium sr using the womac osteoarthritis index. mean importance scores were similar for items within the same dimension as well as between items in different dimensions. in general, low levels of correlation were noted between the ... | 2007 | 1914413 |
| a nonexponential, nonlogarithmic pharmacokinetic dosing method for gentamicin. | 2007 | 1914430 | |
| imaging of the temporomandibular joint in juvenile rheumatoid arthritis. | 2007 | 1932822 | |
| maternal hydration increases amniotic fluid index. | although adequate amniotic fluid (af) volume is considered an important aspect of fetal well-being, the etiology of decreased af volume is not well understood. a randomized blinded trial was designed to examine our hypothesis that maternal hydration would increase the af index in women with low af indexes. women seen in our testing centers were randomized into control or hydration groups. the control group was instructed to drink their normal amount of fluid; the hydration group was instructed t ... | 2006 | 1945215 |
| maternal hydration increases amniotic fluid index. | although adequate amniotic fluid (af) volume is considered an important aspect of fetal well-being, the etiology of decreased af volume is not well understood. a randomized blinded trial was designed to examine our hypothesis that maternal hydration would increase the af index in women with low af indexes. women seen in our testing centers were randomized into control or hydration groups. the control group was instructed to drink their normal amount of fluid; the hydration group was instructed t ... | 2006 | 1945215 |
| effects of experimental hyper- and hypothyroidism on natural defense activities against lewis lung carcinoma and its spontaneous pulmonary metastases in c57bl/6 mice. | the effects of expermentally induced hyper- and hypothyroidism on the growth and development of spontaneous pulmonary metastases of lewis lung carcinoma (3ll) cells were studied in a murine system. progression of 3ll tumors growing in mice was associated with significant reduction in the serum levels of t3 and t4. subcutaneous (s. c.) injections (3 times/week) of t3 resulted in a hyperthyroid state with elevated t3 and reduced t4, whereas treatment with t4 induced a hyperthyroid state with eleva ... | 1991 | 1948998 |
| interpersonal aspects of the supervision of individual psychotherapy. | both the pleasures and pains of psychotherapy supervision have been described for the three parties--resident, supervisor, and patient--involved in such work. although both positive and negative aspects have been included in order to be comprehensive, it is clear to those who have engaged in supervision for many years that the pleasures far outweigh the pains for those concerned. a variety of means of facilitating the growth and increasing the knowledge of student psychotherapists have been unde ... | 2007 | 1951784 |
| [microbiological care of ventilated intensive care patients. feasibility of diagnosis and therapy of pulmonary infection]. | pulmonary infections are the most life-threatening infections in mechanically ventilated patients. methods to avoid these infections by prophylactic systemic or local administration of antibiotics may promote resistance and selection of distinct groups of pathogens. in mechanically ventilated patients we studied the impact of early diagnosis and specific therapy on the prevention of pulmonary infections. due to the very short interval between colonization and infection, daily microscopic and mic ... | 1991 | 1952044 |
| differentiation of the chick embryo floor plate. | in a number of species, the floor plate of the developing neural tube and spinal cord has been ascribed specialized functions associated with the patterning of neuronal differentiation. the differentiation of the floor plate itself is believed to be closely related to the presence of the underlying notochord. grafting experiments have previously shown that in the chick embryo an implanted segment of notochord is capable of inducing the adjacent host neural plate or neural tube to produce an addi ... | 2007 | 1952103 |
| effects of beta-casomorphin derivatives on gastrointestinal transit in mice. | some d-amino acid-substituted derivatives of beta-casomorphin (cm) were found to exhibit a special affinity to central opiate receptors. concerning their affinity to peripheral opiate receptors our knowledge is still limited. the results of our experiments indicate that cm derivatives interfere with peripheral opiate receptors and that there is a close connection with the affinity to different subtypes of this receptor. | 2007 | 1965564 |
| coeliac disease. | 2007 | 1976395 | |
| characterization of refractory period extension by transcardiac shock. | to better understand the refractory period extension (rpe) produced by transcardiac shocks and its possible role in defibrillation, we measured rpe under various experimental conditions. | 1991 | 2040057 |
| an evaluation of waist to hip ratio measurement methods in relation to lipid and carbohydrate metabolism in men. | the purpose of this study was to determine which method of measuring waist to hip ratio (whr) was the most effective in assessing decrements associated with an abdominal fat distribution in 46 non-obese, middle to older aged men (mean +/- s.e., age 52.8 +/- 0.88 years; body fat 19.7 +/- 0.72 percent). circumferences were obtained at the following sites and whr calculated (waist circumference/hip circumference): (1) minimal waist/maximal hip; (2) level of umbilicus/maximal hip; (3) level of umbil ... | 2007 | 2045211 |
| bullous pemphigoid antigen: cdna cloning, cellular expression, and evidence for polymorphism of the human gene. | a human epidermal keratinocyte lambda gt11 recombinant cdna library was screened with a 0.45-kb cdna that was generated by polymerase chain reaction (pcr) amplification of a segment of human bullous pemphigoid (bp) antigen mrna. the screen yielded five clones, the largest one, pcbpa-4, being 2.3 kb in size. the pcbpa-4 cdna hybridized in northern analyses with an approximately 9-kb mrna from cultured keratinocytes, whereas no hybridization signal was detected with rna from human skin fibroblast, ... | 1991 | 2045679 |
| [differential roentgenological diagnosis of injuries of the lower cervical vertebrae]. | on the basis of 14 experiments with simulation of the lower cervical vertebra dislocations on cadavers and human cervical vertebra blocks, combined with stage discography, the authors singled out 3 groups of +disk and ligament structure damages: damage of capsular--ligamentous apparatus of the rear support complex; damage of ligamentous--capsular apparatus and disk; damage of ligamentous-capsular apparatus, frontal longitudinal ligament and total rupture of a disk. differentiation is made accord ... | 1990 | 2074961 |
| the effects of oral contraceptives on well-being and sexuality. | the extent to which the high discontinuation rate for oral contraceptives is due to adverse effects of mood, well-being and sexuality is explored, taking into account early studies on high dose combined and sequential pills, recent studies on low-dose combined and triphasics, experimental design factors, effects of ocs on free androgen levels, psychosocial factors and reasons for choosing or stopping pills, effects on depressive illness, premenstrual syndrome, sexuality, and possible mechanisms ... | 2007 | 2075004 |
| [recurrent thromboembolism disclosing protein c deficiency. apropos of a case with familial investigation]. | every thromboembolic manifestation, especially in young subjects, calls for an aetiological study in which haemostasis is evaluated primarily with assays of physiological coagulation inhibitors: protein c, protein s and antithrombin iii. protein c deficiency is found in 6 to 7% of thromboembolic manifestations. we report the case of a 21-year old man who had phlebitis followed by pulmonary embolism without facilitating factors. protein c level was 50% of normal value (0.50 iu/ml). the patient re ... | 1990 | 2075365 |
| oxygen-transport fluid based on perfluorochemicals: effects on liver biochemistry. | the effects of (1) i.v. injection of various perfluorochemical (pfc) emulsions, (2) different fractions of the non-ionic poloxamer surfactant, pluronic f-68, or (3) i.p. injection of component pfc oils have been studied separately in male and female rats. injection of 10 ml/kg body wt of either fluosol-da 20% (f-da) or a novel perfluorodecalin emulsion containing a c-16 oil additive in male rats increased liver weight up to 7 days later; no corresponding effect occurred in response to injection ... | 1990 | 2096632 |
| dual functions of insect immunity proteins in defence and development. | 2007 | 2100024 | |
| transvaginal sonography in early pregnancy. | 1963 | 2106242 | |
| susceptibility to lysis of pulmonary alveolar macrophages by human lymphokine-activated killer cells. | in this study we addressed the question of whether lymphokine-activated killer (lak) cells, besides killing neoplastic cells, may exert a certain degree of lysis on the normal counterpart; in particular we took into consideration the toxicity against pulmonary alveolar macrophages (pam). we demonstrated that human lak cells generated in vitro following incubation of peripheral blood mononuclear cells with recombinant interleukin 2 for 4 days were able to lyse normal pam in a 4-h 51cr release ass ... | 1990 | 2106387 |
| prevalence of psychiatric disorders in a mandatory screening program for infection with human immunodeficiency virus: a pilot study. | ninety-five randomly selected human immunodeficiency virus (hiv)-seropositive air force personnel were psychiatrically examined during a routine medical evaluation. of the 95, 95% did not have acquired immunodeficiency syndrome and were largely asymptomatic; 61.1% had clinical axis i diagnoses, which included simple phobia, adjustment disorders, hypoactive sexual desire disorder, alcohol use disorder, major depression, and organic mental disorders; 30.5% had personality disorders. significantly ... | 1990 | 2106656 |
| cell cycle kinetics of insect cell cultures compared to mammalian cell cultures. | cell cycle kinetic of lepidopteran cell lines sf9 (spodoptera frugiperda) and izdmb0503 (mamestra brassicae) were investigated and compared to mammalian cell cycle distributions. the resting phase (g0) of mammalian cells is characterized by a 2c-dna content whereas g0-phase of insect cell lines is characterized by a 4c-dna content. flow cytometric data in combination with growth curves of partially synchronized and asynchronously growing cells proved the existence of this phenomenon. kinetics of ... | 1990 | 2142463 |
| interactions between estrogens, androgens, progestins, and glucocorticoids in zr-75-1 human breast cancer cells. | the human breast cancer cell line zr-75-1 possesses androgen, estrogen, progesterone, and glucocorticoid receptors, thus offering a good model to study the specific role of each class of steroids in the control of breast cancer growth. although the stimulatory action of classical estrogens (e2 and estrone) is well known, we have found a potent mitogenic effect of the adrenal estrogen androst-5-ene-3 beta,17 beta-diol (delta 5-diol) at concentrations within the range of those found in the serum o ... | 1990 | 2142871 |
| quality of life measurement--breast cancer. | 1998 | 2143942 | |
| preparation and characterization of anti-paroxetine antibodies. | 6-nitroparoxetine was synthesized and reduced to 6-aminoparoxetine. after coupling to glutaraldehyde at the 6-position and to bovine serum albumin, the resulting schiff's base was further reduced into an amino-derivative which served as the antigen. anti-paroxetine antibodies were raised against this antigen in rabbits and the anti-paroxetine igg purified by protein a affinity chromatography. the anti-paroxetine igg demonstrated high specificity towards paroxetine and 6-nitroparoxetine without s ... | 1990 | 2147049 |