PMID(sorted ascending)
free radical formation in pyrimidine derivatives: a study of 5-nitrouracil at 77 k. 2003164682
genital herpes: the source of infection. 2003165158
[relation between endocrinology and psychiatry. some recent developments].relations between endocrinology and psychiatry are developing in two main directions: behavioural effects of hormones. after the effects of peripheral hormones, recent works are concerned with a.c.t.h. and antidiuretic hormone (which interfere with memory process) and with hypothalamic peptides (which might have psychotropic properties, independant of their endocrine regulation function). -correlations between psychiatric syndroms and endocrine disorders. in some mentally depressed patients, dis ...2003165466
persistent or slow viral infections and related diseases.the discovery of persistent transmissible agents by veterinarians has led to striking advances in the infectious cause of neuropathies of human beings. there is evidence for persisting infection in congenital rubella and the herpes group of viruses including cytomegalovirus infections. hepatitis types a and b are candidates for inclusion in the category of persisting viral infections. the rubeola or measles virus is established as a persistent virus which causes elevated antibodies in the serum ...1975165638
behavioral effects of dibutyryl cyclic 3'5'amp and biogenic amines in rats.white male wistar rats were injected intraventricularly with 200 mug of dibutyryl cyclic 3'5'amp (damp. 30 min later part of animals was injected intraventricularly with 10 mug of dopamine (da), 10 mug of 5-hydroxytryptamine (5-ht) or 50 mug of acetylcholine (ach). immediately after injection of the amines the time of walking, convulsions, immobility and number of jumps during 10 min periods of observation was measured. damp induced excitation of animals expressed by convulsions, jumping and sho ...1975165657
nitric oxide complexes of cytochrome p-450. 1975166885
[anti-lipoprotein autoantibodies with hypolipidemia in infectious rheumatism].presence of anti-lipoprotein activity, a new serological finding in inflammatory rheumatoid disease, has been established in sera and synovial fluids of 20 patients, among which were 6 cases of ankylosing spondylitis. in 18 of the patients, sera were negative for rheumatoid factor. anti-lipoprotein activity can best be demonstrated by the hemagglutination technique. the binding activity is directed against autologous as well as homologous, however not against heterologous hdl and ldl. it has no ...1997168637
structure of a 30 s pre-ribosomal rna of e. coli. 1975169158
[morphology of the motor endplate. aspects of interest in neurology]. 2003170897
[isoenzymes in neoplasms]. 1976176637
hormone-induced diarrhea in a healthy subject infusions of either secretion or glucagon caused no diarrhea. a combinations of gastrin and glucagon induced severe watery diarrhea immediately after the end of the 3 hour infusion. no diarrhea occurred from the combination of secretin and gastrin.1975176861
rubrospinal effects on ventral spinocerebellar tract neurones.stimulation of the contralateral red nucleus evoked monosynaptic epsps in 14 of 82 ventral spinocerebellar tract neurones. in some of these cells the monosynaptic epsp was followed by a disynaptic ipsp. the remaining cell population received di- or polysynaptic psps from the rubrospinal tract, either epsps or ipsps or both. convergence of the rubrospinal tract onto interneurones of the segmental pathways projecting to vsct cells was demonstrated. rubrospinal volleys facilitated disynaptic ia ips ...1976176875
tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton.a new dominant mutation, tight-skin (tsk), is located on chromosome 2, two recombination units distal to pallid (pa). heterozygotes (tsk/+) have tight skins with marked hyperplasia of the subcutaneous loose connective tissues, increased growth of cartilage and bone, and small tendons with hyperplasia of the tendon sheaths. in the loose connective tissue there are large accumulations of microfibrils in the intercellular space. in spite of the increased skeletal size, body weight is not increased. ...1976176891
re-evaluation of the role of cyclic amp in histamine-induced gastric acid secretion.the 600 x g particulate fraction of gastric mucosal scrapings from rats was incubated with 3h-metiamide which saturated available binding sites at a concentration of 1 mum. scatchard plots showed a single component with a kd value of 0.2 mum. unlabelled cimetidine and histamine competed with 3h-metiamide binding. the 600 x g particulate fraction also contained all of the hormone and sodium fluoride sensitive adenylyl cyclase. adenylyl cyclase activity was not altered by histamine, pentagastrin o ...1976177326
vasopressin-sensitive kidney adenylate cyclase: modulation of the hormonal response.vasopressin-sensitive pig kidney adenylate cyclase is sensitive to several effectors, such as mg2+, other divalent cations, and guanyl nucleotides. the purpose of the present study was to compare the main characteristics of adenylate cyclase activation by vasopressin, mg2+, and gmppnp, respectively. mg2+ ions were shown to exert at least three different effects on adenylate cyclase. the substrate of the adenylate cyclase reaction is the mg-atp complex. mg2+ interacts with an enzyme regulatory si ...1976177820
aspiration cytology of salivary gland tumors: diagnostic experience from six years of routine laboratory work.fine-needle aspiration cytology has been used as a routine diagnostic instrument in patients with salivary gland lesions during 1966-1972. a retrospective analysis of the primary cytologic reports correlated with the revised final diagnoses in 461 patients where a pathologic report is available, shows exact agreement in 63 percent, good and not misleading agreement in a further 18 percent, while false reports were initially given in 8 percent, and unsatisfactory specimens were obtained in 11 per ...1996177833
17 alpha estradiol: separation of estrogen effect on collagen from other clinical and biochemical effects in rodents the effect of 17alpha estradiol upon collagen is identical to that of 17beta estradiol, but the 17alpha estradiol effect upon uterine lining is 1/1000 that of 17beta estradiol. both steroids reverse the effect of d-penicillamine on rodent skin collagen. five human beings with the skin collagen changes associated with d-penicillamine were treated with 17alpha estradiol for three to six weeks. 17alpha estradiol caused no detectable changes in blood pressure, breast development, menstrua ...1976178033
[biochemical method of estimating the degree of malignancy of transplantable hepatomas]. 1996178490
electron microscopic features of lipoprotein-glycosaminoglycan complexes from human atherosclerotic plaques.lipoprotein-glycosaminoglycan (gag) complexes were isolated from fibrous plaque lesions of human aortas and examined by electron microscopy. after fractionation by gel chromatography and ultracentrifugation, both very low density lopoprotein-gag and low density lopoprotein-gag complexes showed particles which were mainly 1,000 to 2,000 a in diameter. occasional large aggregations 3,000 to 10,000 a in diameter were seen after gel filtration and in the very low density lipoprotein fraction of comp ...1976178962
brief communication effects of estradiol on feeding and locomotion in rem deprived rats. 1976179107
a comparison of lung cancer antigens. 1997179173
[molecular aspects of the formation of mitochondrial membranes]. 1976179238
fine structural analysis of rabbit synovial cells. ii. fine structure and rosette-forming cells of explant and monolayer cultures.the fine structure and plasma membrane receptors of explant and monolayer cells of normal rabbit synovium were studied. in explants about 10% of the cells were round and formed rosettes with igc and c3 markers, whereas the remaining cells were stellate, resembled young fibroblasts, and had no receptors for igg and complement. monolayer cells looked like fibroblasts, produced fine extracellular fibrils and hyaluronate, and formed no rosettes. thus early cultures contain both macrophages and fibro ...1976181009
type-c rna viruses and leukemogenesis: relation of type-c virus infectivity and leukemogenesis induced by nitrosourea compounds in mice.correlation between infectivity of type-c rna virus) murine leukemia virus, mlv) and development of leukemia was tested in female icr/jcl mice treated with either 1-ethyl-1-nitrosourea (enu) or 1-butyl-1-nitrosourea (bnu). continuous administration of either chemicals resulted in the occurrence of thymic lymphoma in every mouse with a short latent period. the time of appearance and distribution pattern of mlv infectivity in various tissues were examined by the xc plaque assay technique at fixed ...1976187521
results of intermittent treatment of growth hormone deficiency with human grwoth hormone.the growth in stature of two groups of growth hormone deficient children has been compared. the frist group received intermittent treatment with human growth hormone (hgh), 1 year on, 1 year off, subsequent years on; the second group received continous treatment. this latter group had a significantly better mean growth response. the reduction in treatment velocity in years subsequent to the first was not prevented by the year off treatment, the mean velocity of the intermittent group in their 3r ...1977194914
hyperalpha- and hypobeta-lipoproteinemia in octogenarian kindreds. 2003196605
effect of dihydroergotoxine on cyclic-amp-generating systems in rat cerebral cortex slices of rat cerebral cortex, cyclic-amp formation is stimulated in response to added noradrenaline (na), isoproterenol (isp) or adenosine. the effect of isp could be antagonized only by the selective beta-adrenoceptor-blocking agent pindolol, whereas the stimulating effect of na could be antagonized by both alpha- and beta-adrenoceptor-blocking agents. dihydroergotoxine (dhet) at low concentrations (10(-8)m) antagonized the stimulating effect of na but not of isp or adenosine, suggesting th ...1978201544
fetal mouse lung in circumfusion system cultures.fetal mouse lungs were cultivated, using the dual-rotary circumfusion system for tissue culture, and their histotypic development was surveyed for 75 days by phase-contrast and electron microscopy. alveoli, terminal bronchioles and alveolar macrophages were photographed periodically with still and time-lapse phase-contrast microscopy. their histotypic appearance was confirmed by electron micrographs of the 1- and 2 1/2-month-old specimens. these revealed typical alveoli surrounded by a basal lam ...1977201560
functions of apical membrane of toad urinary bladder: effects of membrane impermeant reagents. 1993202172
[post-tuberculosis syndromes in a pneumology unit].with reference to 156 patients with a post-tuberculous syndrome, admitted to a pneumology unit, the authors discuss the anatomoclinical aspects of the primary disease and morbid entities developing against the background of the sequelae. the circumstances in which chronic bronchitis develops and post-tuberculous bronchopulmonary suppuration, frequently encountered in the pathology secondary to stable tuberculosis are analyzed. the necessity of preventing potential unspecific diseases and insurin ...1993204973
prolonged infection of l cells with vesicular stomatitis virus. defective interfering forms and temperature-sensitive mutants as factors in the infection. 1978206006
[the effect of vitamin d3 on some parameters in the serum and bone of rats (author's transl)]. 1978206364
ca2+/protein modulator-dependent and -independent cyclic gmp phosphodiesterase from hog heart.ca2+/protein modulator-dependent and -independent guanosine 3':5'-monophosphate (cgmp) phosphodiesterases were separated from hog heart. the protein modulator-free ca2+/protein modulator-dependent enzyme was partially purified by repeated deae-cellulose column chromatography and heat treatment. the final preparation of this enzyme showed no significant basal activity under the standard assay conditions. lineweaver-burk plots of the ca2+/protein modulator-dependent enzyme activity indicated the p ...1978207685
histochemical, pharmacological and microspectrofluorometric analysis of new sites of serotonin localization in the rat hypothalamus.histopharmacological and microspectrofluorometric analysis was applied to the rat hypothalamus for the identification of serotonin. neuronal perikarya, especially certain of those of the endocrinologically important arcuate nucleus, were seen to contain a yellow histofluorescence which possessed spectral characteristics consistent with the serotonin fluorophor. serotonin was localized also within varicosities of various hypothalamic nuclei, as well as within an ependymally associated network of ...1978207746
[effect of rations with an increased sunflower seed oil level on the rate of very low-density lipoprotein formation in the liver, secretion into the blood and composition in the blood].feeding of rats on a ration with an excessive content of sunflower-oil (60 per cent of the total calorific value of the ration) for a period of 30 days resulted in lowering the rate of the apoproteins, prolipoproteins synthesis in the liver and in their loading with triglycerides and cholesterol. as a consequence of this it diminished secretion of endogenously formed tryglycerides and cholesterol from the liver into the blood and a changed lipid composition of lipoproteins of a very low density ...1978208301
[mechanisms of hydrochloric acid secretion in the stomach and the nature of nutrition (a review of the literature)]. 1991208302
the identity of alpha-galactosidase b from liver. 1991208365
nerve conduction velocity of small components in human sensory nerves. studies in normal and diseased nerves.slow conducted components of sensory nerve action potentials were investigated in median and in sural nerves of controls and in patients with peripheral nerve diseases. in the normal group the slow components showed no relation to age which is in contrast to the maximum velocity. in both the median nerve and sural nerve of about 20% of the patients with neuropathy exclusively a decrease of the conduction velocity of slow components was found, the other investigated parameters were normal. possib ...1977210021
vestibulo-ocular reflex from the posterior canal nerve to extraocular motoneurons in the the anesthetized cat, the posterior canal nerve (pcn) was stimulated by electric pulses and synaptic responses were recorded intracellularly in the three antagonistic pairs of extraocular motoneurons. pure reciprocal effects were obtained in the motoneurons innervating the antagonistic pair of ipsilateral oblique muscles and the antagonistic pair of contralateral vertical rectus muscles. these responses consisted of low threshold disynaptic excitatory postsynaptic potentials (epsps) in either ...1978210032
radioimmunological determination of free (diffusible) cortisol in an equilibrium dialysis system. 1989210267
[evaluation of renal cyclic adenosine monophosphate, serum parathyroid hormone and phosphate reabsorption in recurrent calcium urolithiasis, healthy controls and hyperparathyroidism (author's transl)].in three groups (n = 12 each) of male controls (22--43 years), patients with recurring calcium urolithiasis (21--36 years) and hyperparathyroidism (hpt; 17--71 years) proven by surgery renal cyclic adenosine monophosphate (rcamp), fractional tubular phosphate reabsorption and serum parathyroid hormone (pth) were measured during endogenous creatinine clearance. rcamp (mumol/g creatinine) was: controls 1.48 +/- sem 0.27; stone formers 2.037 +/- 0.343 (not significantly different); hpt 6.234 +/- 0. ...1989210311
enkephalin-like material in normal human csf: measurement and levels. 1978210344
role of ca++ in virus-induced membrane fusion. ca++ accumulation and ultrastructural changes induced by sendai virus in chicken erythrocytes.some of the ultrastructural (freeze-etching technique), morphological, and biochemical effects of sendai virus interaction with chicken erythrocytes have been studied under fusogenic (in the presence of cacl2) and nonfusogenic (in the presence of ethyleneglycol-bis-n,n'-tetraacetic acid, [egta]) conditions. the following phenomena occur, irrespective of the presence of cacl2 or egta: (a) binding of iodinated virus particles to chicken erythrocytes at 4 degrees c and their partial release from th ...1978211140
detection of antigenically active mutant hgprt after mutagenesis with simian virus 40. 1978211410
staging procedures and prognostic features in small cell anaplastic bronchogenic carcinoma. 1988211639
[change in natural immunity under the effect of cysteine]. 1978211758
the effects of reserpine on hypothalamo-pituitary adrenocortical function. 1987212345
comparison of interferon action in interferon resistant and sensitive l1210 cells.translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...1978212514
the lipid-chemical features of the metastatic tissues into the liver from the human gastric cancer, large intestinal cancer and malignant order to clarify the biochemical features of metastatic tissues into the liver of human cancerous cells, 12 of primary cancerous tissues and 3 of metastatic tissues of the large intestinal cancer, 6 of primary cancerous tissues and 2 of metastatic tissues of the gastric cancer, and 3 of primary cancerous tissues and 3 of metastatic tissues of malignant insulinoma were studied lipid-chemically. cancerous tissues and metastatic tissues into the liver were collected by biopsy or surgical operati ...1978212845
primary afferent depolarisation of tooth pulp afferents is not affected by naloxone. 1978213729
[technics of measuring the motive force of very small ameboid cells].a technic have been perfected which measures directly the motive force of very small ameboid cells and indicates the tropism of the amoeba. by using this technic, the motive force of entamoeba histolytica was measured. it varied between +/- 1.5 x 10-4 dyne. we have also shown chimiotactism in entamoeba histolytica. the metabolic coumpound excreted by this cell induced negative tropism.1978213820
hereditary fructose intolerance: a difficult diagnosis in the adult. 1987213970
adenylate cyclase and phosphodiesterase from brain tissue: different stabilities during incubation of cerebral cortical slices.adenylate cyclase and phosphodiesterase were prepared from brain slices from guinea-pig. the specific activity of adenylate cyclase declined rapidly with increasing incubation time of tissue slices, while phosphodiesterase activity was almost uneffected by the incubation of brain slices.1978214325
[antihypoxic effect of analogs of cyclic adenosine monophosphate, phosphodiesterase inhibitors].a number of investigated camp derivatives are shown to inhibit the camp-phosphodiesterase in brain tissues of white rats in vitro. the 8-substituted aminoethylamino-derivatives proved to be effective inhibitors of the enzyme. among them the most pronounced inhibition displayed the 8-(beta-aminoethylamino)-camp. in an in vitro experiment on the model of hypoxic hypoxia in rats it was shown to possess strong anti-hypoxic properties. the possible prospective clinical use of the camp analogs--inhibi ...1978214339
isoproterenol-induced desensitization of adenylate cyclase in human astrocytoma cells. relation of loss of hormonal responsiveness and decrement in beta-adrenergic receptors.incubation of human astrocytoma cells (1321n1) with low concentrations of isoproterenol results in a specific loss of responsiveness to catecholamines as evidenced by a decreased accumulation of camp in intact cells, a reduction in isoproterenol-stimulated adenylate cyclase activity, and a decrease in beta-adrenergic receptor density, as measured by the specific binding of 125i-hydroxybenzylpindolol. the kinetics of desensitization suggest the involvement of two different reactions. the initial ...1979214444
recessive dystrophic epidermolysis bullosa. evidence for increased collagenase as a genetic characteristic in cell culture.fibroblast cultures from patients with recessive dystrophic epidermolysis bullosa (rdeb) demonstrated an increased capacity to synthesize and secrete collagenase. this phenotypic trait appeared to distinguish rdeb from other genetically distinct forms of epidermolysis bullosa. the finding of increased collagenase may be a specific manifestation of these cells in that prototypic lysosomal and cytoplasmic enzymes were present in approximately normal concentrations. in addition, this trait persiste ...1986214508
[senior citizen-movement; self help organization of the older generation]. 1986214634
[hepatocellular carcinoma simulating an acute abdomen]. 1985214828
spectroscopic studies on invertebrate myosins and light chains. 1986215199
glycosylation of a membrane protein is restricted to the growing polypeptide chain but is not necessary for insertion as a transmembrane protein. 1978215329
hepatocellular carcinoma in the u.s.a., etiologic considerations. localization of hepatitis b antigens.the serologic and tissue markers of hepatitis b virus (hbv) were studied in 50 patients in whom hepatocellular carcinoma (hcc) was confirmed at autopsy. serologic and tissue markers included serum hepatitis b surface antigen (hbsag), tissue hbsag, tissue hepatitis core antigen (hbcag), and serum antibody to hbcag (anti-hbc). twenty-two patients had hcc arising in alcoholic cirrhosis; 2 of the 22 (9.1%) had one or more of the hbv tissue and serologic markers. this infection rate is similar to the ...1979215488
[unusual evolution of 2 tympano-jugular chemodectomas]. 1984215700
potentiation of coxsackievirus b3 infection in adult mice pretreated with a gold mice treated with sodium aurothiomalate (myocrisin), prior to infection with coxsackievirus b3, 90% of the animals died by the 11th day postinfection (p.i.). a mortality of 10% was noted in mice receiving myocrisin only, and no deaths occurred in animals infected with virus alone. the highest amount of virus was recovered from the pancreas of myocrisin-treated mice on day 3 p.i. this was over 500-fold higher than the virus titer found in the pancreas of mice infected with virus only. generall ...1978215719
interaction between alpha adrenergic and serotonergic activation of canine saphenous veins.serotonin and norepinephrine produced concentration-dependent contractions of helical strips of canine saphenous veins. the contractile responses to both agonists were inhibited by the alpha adrenergic receptor blocking agent phentolamine. tolazoline inhibited the contractile responses of canine saphenous veins to norepinephrine but augmented those to serotonin. blockade of adrenergic neuronal reuptake with cocaine enhanced the sensitivity of the canine saphenous vein to serotonin, but did not s ...1978215746
[significance of computed tomography in therapeutic diagnosis of brain tumors (author's transl)].because of its noninvasive property of direct imaging of the size and shape of the lesion, ct scan is significant not only for the diagnosis of the brain tumors, but also for the assessment of its chronological and/or therapeutic change in size. contrary to the conventional cerebral angiography and contrast encephalography, ct scan is feasible to detect the tumor repeatedly at short intervals. from march 1976 to october 1977, 197 cases of brain tumors were examined by ct, 6 tumors (1 pineal tumo ...1985215926
[excision of a gigantic glomus jugulare tumor after preoperative embolization]. 1981216069
stimulation of host dna synthesis and induction of early antigens by ultraviolet light irradiated human cytomegalovirus.the ultraviolet (uv-)sensitivity of the human cytomegalovirus (hcmv) genes coding for very early complement fixing and early antigens in human embryonic fibroblasts (hef) and mouse embryonic fibroblasts (mef) and the relation of these genes to the ability of the virus to stimulate host cell dna synthesis were investigated. after 14 minutes of uv-irradiation of the virus inoculum only the very early complement fixing nuclear antigen (cmna) developed in the hef cells and only the early cytoplasmic ...1978216335
d-ala2, deltazphe4-methionine enkephalin amide, a dehydropeptide hormone. 1982216357
what causes atherosclerosis? 1982216608
microbiological aspects of polyphosphate injection in the processing and chill storage of poultry.during commercial processing of broiler chickens, injection of polyphosphate (puron 604 or 6040) resulted in microorganisms being added to the deep breast muscle. the level of contamination was related to the microbiological condition of the injection solution. injection of polyphosphate had no effect on the shelf-life of fresh chilled carcasses held at 1 degree of 10 degrees c but changes were observed in the growth rate of microorganisms in the deep muscle and in the composition of the muscle ...1979216743
xencsa: cell surface antigens related to the major glycoproteins (gp70) of xenotropic murine leukemia viruses. 1979216748
kinetic investigations of the autoxidation of adrenalin.generation rates of superoxide anions (o2-) by autoxidizing adrenalin at ph 9.5 were determined in solutions containing either superoxide dismutase (0.85 m-1 s-1) or hydroxylamine (0.0185 m-1 s-1) as competitive scavengers. the rate constants of o2- with adrenalin and hydroxylamine were calculated for neutral and alkaline solutions. the respective values were for adrenalin: 5.6 x 10(4) m-1 s-1, ph 7.8; 7.0 x 10(3) m-1 s-1, ph 9.5--and for hydroxylamine 5.9 x 10(4) m-1 s-1, ph 7.8; 3.4 x 10(4) m- ...1981217185
[radiotherapy of carcinoma of the nasopharynz: clinical results (author's transl)].a series of 64 patients with malignant tumours of the nasopharynx treated by cobalt irradiation is analyzed. the crude 5-year survival rate for the entire epithelial group was 32%; 55% for n- group, 25% for n+. treatment methods avoiding complications are discussed.1983217394
role of peripheral side chains of vitamin b12 coenzymes in the reaction catalyzed by dioldehydrase. 1979217415
[state of vascular tone and several blood biochemical indices in experimental atherosclerosis and sensitization].a study of the vascular tone of the posterior extremities in rabbits, of some blood lipid metabolism indices under conditions of experimental atherosclerosis and sensitization showed an increase in the vascular resistance in the areas investigated, and disturbance of lipid metabolism in two experimental groups of animals. the data obtained support the literature evidence that allergic component serves as one of the factors complicating the atherosclerosis course.1979217466
characterization of the inotropic response induced by stimulation of beta-adrenergic and h1 histaminergic receptors in guinea pig left atria.the inotropic response induced by beta-adrenergic and h1 histaminergic receptor stimulation was characterized in guinea pig left atria by obtaining dose-response relationships for isoproterenol and histamine under various experimental conditions. conditions (hypothermia, high frequencies of stimulation, and large extracellular calcium concentrations) which enhanced the ability of cardiac muscle to develop force also increased the sensitivity of the left atrium to isoproterenol while decreasing i ...1978217510
serum thymic factor in subacute sclerosing panencephalitis patients. 1983217563
sertoli cell capacity to metabolize c19 steroids: variation with age and the effect of follicle-stimulating hormone. 1978217658
[adrenal cortex and vitamin pp. the effect of corticosteroids on the nad level in the rat liver after the administration of excess nicotinic acid or nicotinamide].the nad content in the liver was experimentally studied in intact, adrenalectomized rats and those given hydrocortisone following nicotinic acid and nicotinamide administration. the nad concentration in the liver rose linearly and equally during the first 4 experimental hours after the nicotinamide administration (200 mg/kg). a conclusion was drawn that in administration of exogenous precursors the coenzyme biosynthesis did not depend on the initial hormonal background.1979218187
biological and biochemical properties of defective interfering particles of equine herpesvirus type 1. 1979218357
a laser spectrofluorimeter for studies of cultured cells on the growth surface. 1979218475
inpatient psychiatric women's groups: the concept of sexuality. 1985219190
specific protein phosphorylation in interferon-treated uninfected and virus-infected mouse l929 cells: enhancement by double-stranded rna.the enhanced phosphorylation of specific protein(s) observed in extracts from interferon-treated cells (in the presence of atp and double-stranded [ds] rna) was also seen in intact mouse l929 cells upon treatment with dsrna, polyriboinosinic.polyribocytidylic acid [poly(ri.rc)] or reovirus dsrna, using 32pi as radiolabel. labeling of a 65,000-dalton protein(s) with 32p was greatly increased in interferon-treated cells in the presence of added dsrna, suggesting that the expression in vivo of the ...1979219224
subacute infection with temperature-sensitive vesicular stomatitis virus mutant g41 in the central nervous system of mice. i. clinical and virologic studies.inoculation of three- to four-week-old balb/c mice with temperature-sensitive (ts) vesicular stomatitis virus mutant g41 produced a subacute neurological disease, initially characterized by development of lethargy, hunched posture, and ruffled fur within five to seven days after infection. more than 90% of infected mice developed these clinical signs. in approximately 60% of infected mice, the initial neurological signs proceeded to striking hind-limb paralysis and weight loss. these signs usual ...1979220328
melanotic neuroectodermal tumor of infancy. an ophthalmic appearance.fullness developed in the left side of a 5-month-old male infant's face in the region of the zygoma. an incisional biopsy specimen showed the mass to be a melanotic neuroectodermal tumor, and radical excision was performed. there has been no recurrence of the tumor one year later. tumors of this type occur in the face, particularly in the maxilla, and have only rarely been reported around the orbit.1962220942
effects of the intravenous administration of calcium on nephrogenous cyclic amp: use as a parathyroid suppression test.the question of parathyroid autonomy in primary hyperparathyroidism has been the subject of conflicting immunoassay data. we studied the effects of calcium infusion (12 mg/kg/3h) and calcium injection (3 mg/kg/10 min) on peripheral plasma parathyroid hormone (ipth) determined with a multivalent antiserum and on the excretion of nephrogenous cyclic amp in normal subjects and in 7 patients with primary hyperparathyroidism who displayed only mild, intermittent hypercalcemia. in control subjects, ca ...1982221521
adrenocortical function, electrolyte metabolism, and blood pressure during prolonged adrenocorticotropin infusion in juvenile hypertension.the effect of a continuous 5-day acth infusion (40 u/24 h) on adrenocorticoid function, electrolyte metabolism, and blood pressure was investigated in eight normotensive children and eight patients with hypertension of unknown origin. there was a continuous rise of plasma cortisol and deoxycorticosterone in all patients. plasma aldosterone rose transiently in the normotensive and the hypertensive group. a transient kaliuresis and a continuous fall in serum k+ were observed in all patients. acth ...1982221530
deinstitutionalization and community placement: clinical and environmental factors. 1983221780
prevention of reactivated herpes simplex infection by human leukocyte interferon after operation on the trigeminal root.microneurosurgical procedures on the trigeminal-nerve root are often followed by reactivation of herpes simplex virus infection, manifested by herpes labialis or oropharyngeal herpesvirus shedding or both. in a double-blind study of the ability of human leukocyte interferon to prevent this reactivation, patients with a history of herpes labialis were given 7 x 10(4) u of interferon per kilogram of body weight per day or placebo for five days beginning on the day before operation. in 18 patients ...1979221812
structural features determining the site specificity of a rat liver camp-independent protein kinase. 1979222263
comparison of cholesterol egress from cultured cells enriched with cholesterol ester after exposure to cationized ldl or to ldl and chloroquine. 1978222329
hypolipidemic effects in dogs of ml-236b, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coa reductase, significantly reduced both serum cholesterol and phospholipid levels in dogs, when used at a dosage higher than 10 mg/kg per day. triglyceride levels were not consistently changed, but beta- and pre-beta-lipoproteins were preferentially reduced. serum cholesterol levels were reduced by 44--45% at the higher dosage of 100--400 mg/kg per day (for 5 weeks) but ml-236b caused no significant changes in the cholesterol conte ...1979223590
[approbation of nutrient media made of dry components for the accelerated cultivation of cl. perfringens type a]. 1979224626
bovine leucosis in portugal. 1978224779
mao activity and eeg sleep in primary depression.platelet monoamine oxidase (mao) activity and electroencephalographic (eeg) sleep measures were examined in 56 drug-free hospitalized patients with primary depression as defined by the research diagnostic criteria. the group included 35 females and 21 males with a mean age of 42.6 +/- 1.4 years. platelet mao and eeg sleep data were compared for the group as a whole and separately for the unipolar, bipolar, male, and female subgroups. no significant relationships could be demonstrated for the ent ...1976233158
dopamine-mediated behavior produced by the enkephalin analogue fk 33-824.intraperitoneal injection of fk 33-824 produced apomorphine-like stereotyped behavior in rats. antagonism of this stereotypy by naloxone and neuroleptics suggests that fk 33-824 can activate opiate and dopamine receptors in the brain. because increased dopaminergic neuronal activity is thought to be involved in schizophrenia and dopamine-mediated stereotypy has been used as an animal model for this illness, these results are consistent with an involvement of endogenous opiate-like peptides in sc ...1979233159
a new, highly sensitive and specific assay for chymotrypsin.1. a simple, highly sensitive, specific fluorometric method for the determination of chymotrypsin is described. 2. the new substrate utilized in this assay, n-glutaryl-glycyl-glycyl-l-phenylalanine beta-naphthylamide (ggpna), is readily soluble in water, stable and highly specific for chymotrypsin. it is not degraded by a large excess of carboxypeptidase b, elastase, thrombin or plasmin and is virtually resistant to trypsin. 3. ggpna is extremely sensitive to the action of chymotrypsin and permi ...1977235387
precursor specific inhibition of hepatic gluconeogenesis by glisoxepide, an inhibitor of the l-aspartate/l-glutamate antiport system. 1975235462
the inhibition of enzymes related to pulmonary fatty acid and phospholipid synthesis by dietary deprivation in the rat. 1975238512
[family and marital therapy. ii. theory and practice]. 1979243303
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