| equine monocytic ehrlichiosis in illinois. | | 1985 | 4055495 |
| adverse reaction to oxytetracycline in a dog. | | 1985 | 4060559 |
| potomac horse fever agent in mice. | | 1985 | 4082426 |
| isolation of cowdria ruminantium by cellular affinity chromatography and detection by an enzyme-linked immunosorbent assay. | the isolation of cowdria ruminantium by means of wheat germ lectin affinity chromatography as described in this paper permits the recovery of partially purified viable organisms under mild conditions in short time. these conclusions are based upon results of analyses of column fractions by intravenous inoculation into sheep, protein determination, electronmicroscopy and enzyme-linked immunosorbent assay. the entire purification procedure could be completed in 4-5 hours using only either infected ... | 1985 | 4088636 |
| the natural resistance of cattle to artificial infection with cowdria ruminantium: the role played by conglutinin. | the conglutinin titres of year-old bonsmara-cross cattle infected with cowdria ruminantium were inversely proportional to the severity of the reactions elicited by the infection. there was no correlation, however, between conglutinin levels of 8-month-old calves of the same breed, sex and origin and their susceptibility to heartwater. the role possibly played by conglutinin in the non-specific resistance of cattle to heartwater and in the epidemiology of the disease is discussed. | 1985 | 4088641 |
| diagnosis of tropical canine pancytopaenia (ehrlichia canis infection) by immunofluorescence. | | 1971 | 4104331 |
| tropical canine pancytopenia: in vitro cultivation of the causative agent--ehrlichia canis. | | 1971 | 4107760 |
| pathogenesis of heartwater. i. cowdria ruminantium in the lymph nodes of domestic ruminants. | | 1970 | 4115310 |
| serological diagnosis of tropical canine pancytopenia by indirect immunofluorescence. | an indirect fluorescent-antibody test for detection and titration of antibodies to ehrlichia canis, the causative agent of tropical canine pancytopenia, has been described. the organism propagated by an in vitro technique in canine blood monocytes served as an antigen in the test. the specificity of the test was revealed by absence of cross-reactivity between the antigen and sera from dogs infected with various common pathogens and specific sera against eight rickettsial species. the accuracy of ... | 1972 | 4118045 |
| multiplication of cowdria ruminantium in monolayer of tick cells. | | 1974 | 4527902 |
| pathology of canine ehrlichiosis (tropical canine pancytopenia). | | 1973 | 4542936 |
| structure of ehrlichia canis in blood monocytes of a dog. | | 1972 | 4641202 |
| the effect of prolonged oral administration of oxytetracycline on the course of heartwater (cowdria ruminantium) infection in sheep. | | 1972 | 4671467 |
| a comparative study of the pathogenicities of old and new world strains of ehrlichia canis. | | 1972 | 4671480 |
| red and gray foxes--potential reservoir hosts for ehrlichia canis. | | 1973 | 4735125 |
| ultrastructure of ehrlichia canis. | the ultrastructure of ehrlichia canis was examined in both pulmonary mononuclear cells and in monocytes cultured from an infected dog. the cytoplasmic inclusions, or morulae, of e. canis consisted of a membrane-lined vacuole-containing elementary bodies which varied in size and number. the elementary bodies were bound by two trilamellar membranes. the organism shared morphological properties of both the genus rickettsia and genus chlamydia. | 1973 | 4735376 |
| ehrlichia canis infection. (tropical canine pancytopaenia or canine rickettsiosis). | | 1973 | 4787762 |
| canine ehrlichiosis (tropical canine pancytopenia): survival of phosphorus-32-labeled blood platelets in normal and infected dogs. | | 1974 | 4813322 |
| relation between carrier-state oxytetracycline administration and immunity in ehrlichia canis infections. | | 1972 | 5041029 |
| ehrlichia canis and tropical canine pancytopaenia. | | 1972 | 5072572 |
| a new strain of ehrlichia canis. | | 1971 | 5128792 |
| studies on ehrlichia canis. | | 1971 | 5148310 |
| the passage of cowdria ruminantium in mice. | | 1971 | 5161403 |
| ehrlichia canis--the causative agent of a haemorrhagic disease of dogs? | | 1969 | 5356929 |
| tropical canine pancytopaenia and ehrlichia canis infection. | | 1970 | 5442103 |
| [preservation of a cowdria ruminantium strain by freezing]. | | 1970 | 5534034 |
| ehrlichia ovina infection. | | 1968 | 5761408 |
| ehrlichia-like rickettsiosis in dogs in oklahoma and its relationship to neorickettsia helminthoeca. | | 1966 | 5913043 |
| [on the localization of cowdria ruminantium in the bronchial epithelium]. | | 1966 | 6011928 |
| positive ehrlichia canis serology in kawasaki disease. | | 1980 | 6103489 |
| rickettsiaceae and chlamydiaceae: comparative electron microscopic studies. | the structure and cytopathology of obligate intracellular bacteria belonging to families rickettsiaceae and chlamydiaceae and their interaction with eukaryotic host cells were compared in electron microscopic studies. "rickettsia-like" and "chlamydia-like" types of organization of bacterial cells and their interaction with host cells are presented. the rickettsia-like type is characterized by short rod-shaped cells multiplying freely ( extravacuolarly ) in the cytoplasm or nucleoplasm of the hos ... | 1984 | 6145350 |
| cross immunity between strains of cowdria ruminantium. | cross immunity tests with strains of cowdria ruminantium from south africa, the sudan, são tomé and nigeria failed to demonstrate antigenic differences. the antibiotic ampicillin showed no activity against heartwater. | 1983 | 6195703 |
| virulence of two strains of cowdria ruminantium in mice and their use to predict drug activity against heartwater. | a study was made of the infectivity of two mouse-adapted strains of cowdria ruminantium in mice. the kwanyanga strain was most virulent in balb/c mice which died nine days after infection with homogenate of liver from infected mice. cd-1 mice were least susceptible of six strains tested. the du plessis strain of c. ruminantium was equally virulent in all six mouse strains. the du plessis strain in cd-1 mice was used as the basis of a drug screen to detect activity against heartwater (c. ruminant ... | 1984 | 6233776 |
| somatic cell hybrids of canine peritoneal macrophages and sv40-transformed human cells: derivation, characterization, and infection with ehrlichia canis. | somatic cell hybrids were obtained by fusion of canine peritoneal macrophages and sv40-transformed human skin fibroblasts. a cell line (wrh-2) was established from a single isolated hybrid clone. the wrh-2 cell line has been serially passaged 60 times and has a population doubling time of approximately 24 hours. karyotypic analysis showed the modal number of chromosomes to be 80, with a selective segregation of canine chromosomes. expression of incorporated canine dna was substantiated by cellul ... | 1980 | 6245605 |
| rickettsia sennetsu in human blood monocyte cultures: similarities to the growth cycle of ehrlichia canis. | microscopic examination of cultured human monocytes infected with rickettsia sennetsu and stained by the giemsa method revealed the presence of various organismal growth forms in the cytoplasm of the infected cells. the growth forms were loosely scattered individual organisms, clusters of organisms, various sizes of dense inclusion bodies in intact and vacuolated cytoplasm, and organisms in close proximity to disintegrated monocytes. the appearance and the morphology of these r. sennetsu growth ... | 1982 | 6274798 |
| [bovine ehrlichiosis in the ivory coast. epidemiology. treatment. prevention]. | | 1983 | 6326208 |
| tick-borne fever: a review. | the literature on tick-borne fever is reviewed. tick-borne fever is a rickettsial disease of sheep and cattle characterised by high fever and severe leucopaenia. the causative agent, cytoecetes phagocytophila invades the neutrophils and monocytes and is transmitted by the tick ixodes ricinus. there is very little information on the pathogenesis and immunogenesis of the disease but there is ample evidence that infected animals are predisposed to other diseases. animals infected with tick-borne fe ... | 1983 | 6349107 |
| heartwater (cowdria ruminantium infection): current status. | | 1983 | 6359836 |
| serologic diagnosis of infectious cyclic thrombocytopenia in dogs using an indirect fluorescent antibody test. | an indirect fluorescent antibody test was used for detection of serum antibodies to the platelet-specific rickettsial organism that is the causative agent of infectious cyclic thrombocytopenia (ict) in dogs. the test converted from negative to positive in 7 of 7 experimentally inoculated dogs. one of 2 attempts to recover the rickettsial agent of ict from naturally occurring seropositive dogs, by blood inoculation of experimental dogs, was successful. seemingly, the test did not detect antibodie ... | 1983 | 6362502 |
| fever and changes in plasma zinc and iron concentrations in the goat: the role of leukocytic pyrogen. | in goats with trypanosomiasis (t. vivax or t. congolense) no marked fall in plasma zinc concentration was seen despite high temperature peaks, whereas plasma concentrations of iron tended to undergo some decline. in goats infected with ehrlichia phagocytophila, there was a marked decline in plasma zinc and iron to low values on the 3rd and 4th day, respectively. circulating endogenous pyrogen (ep) or leukocytic endogenous mediator (lem) could not be detected in plasma from febrile goats with tic ... | 1984 | 6392359 |
| [the 1st case of ehrlichiosis in a horse in germany (brief report)]. | | 1984 | 6397345 |
| the immunization of calves against heartwater: subsequent immunity both in the absence and presence of natural tick challenge. | cattle, vaccinated as calves with cowdria ruminantium-infected tick stabilate, were challenged 6, 12 and 24 months later. in the absence of tick challenge, vaccination of calves induced a partial immunity against subsequent challenge at 12 and 24 months. in animals exposed to ticks, the resistance was no better than that of control, unvaccinated cattle. when they were challenged at 6 months of age there was no difference between vaccinated and unvaccinated calves, either in the absence or presen ... | 1984 | 6398415 |
| rickettsial diseases of the far east: new perspectives. | the rickettsial disease of man found only in asia is mite-borne (scrub) typhus, caused by rickettsia tsutsugamushi. unique to southern japan is a little-known human mononucleosis-like disease caused by rickettsia sennetsu. in 1981 and 1982, there was a remarkable resurgence in the number of reported cases of mite-borne typhus in japan after some years of virtual absence. recent studies of r sennetsu have resulted in its reclassification to the genus ehrlichia, members of which until now have bee ... | 1984 | 6425420 |
| the canine ehrlichiosis (tropical canine pancytopenia) epizootic in vietnam and its implications for the veterinary care of military working dogs. | | 1984 | 6429572 |
| ehrlichiosis in a florida horse. | | 1984 | 6469848 |
| rickettsial link with acute equine diarrhoea. | | 1984 | 6506415 |
| causative agent of potomac horse fever. | | 1984 | 6516201 |
| colostrum-derived antibodies to cowdria ruminantium in the serum of calves and lambs. | antibodies to cowdria ruminantium were detected in the serum of calves born from artificially immunized heifers, by means of the indirect fluorescent antibody test, only for as long as 4 weeks after birth. lambs born from artificially immunized ewes, however, were still serologically positive at 8-12 weeks of age. much higher antibody titres were recorded in the sera of ewes and their lambs than in that of heifers and their calves. | 1984 | 6533520 |
| clinical, haematological and blood biochemical changes in goats after experimental infection with tick-borne fever. | tick-borne fever in goats caused by ehrlichia (cytoecetes) phagocytophila was characterised by high fever, dullness, anorexia, tachycardia and a slight to moderate inhibition of rumen motility. the animals developed a gradual decline in the total number of circulating white blood cells. there was a decrease in lymphocytes over a short period, followed by an increase. the number of neutrophils was higher on the 3rd day, causing considerable change in the lymphocyte:neutrophil ratios. the number o ... | 1984 | 6542720 |
| heartwater in angora goats. i. immunity subsequent to artificial infection and treatment. | this study confirmed reports that angora goats are highly susceptible to cowdria ruminantium and showed that immunization of this breed against heartwater may be difficult hazardous. it was found that if goats were treated on the 2nd or 3rd day of the febrile reaction following the intravenous inoculation of the heartwater agent, few animals survived the infection. if, on the other hand, treatment was instituted on the 1st day of the reaction, the chances of survival were good, but the immunity ... | 1983 | 6634087 |
| treatment and thrombocyte levels in experimentally induced canine ehrlichiosis and canine babesiosis. | three dogs which were carriers of babesia canis were infected with ehrlichia canis. these animals developed clinical signs and haematological evidence of ehrlichiosis and made an uneventful recovery, despite the fact that they were subsequently treated with doxycycline only. three control dogs which were also carriers of b. canis were clinically normal, despite the fact that they showed a distinct drop in the thrombocyte levels associated with increases in the numbers of parasitized red cells. | 1983 | 6676688 |
| efficacy of pyrethroid-impregnated ear tags for prophylaxis of tick-borne diseases of cattle. | | 1984 | 6730269 |
| isolation and transmission of cowdria ruminantium (causal agent of heartwater disease) in blue nile province, sudan. | heartwater was diagnosed in sheep at the umm banein livestock research station, blue nile province, sudan. cowdria ruminantium was isolated from sheep by subinoculation of blood into a goat. adult amblyomma lepidum ticks fed as nymphs on this goat transmitted heartwater to a friesian (bos taurus) calf. brain stabilates from this calf, either snap-frozen into liquid nitrogen or frozen slowly in a deepfreezer at -70 degrees c, with dmso as cryoprotectant, were infective to cattle when inoculated s ... | 1984 | 6740919 |
| experimental transmission of cowdria ruminantium by the gulf coast tick amblyomma maculatum: danger of introducing heartwater and benign african theileriasis onto the american mainland. | the tick amblyomma maculatum proved to be an experimental vector of cowdria ruminantium, the cause of heartwater of ruminants. transstadial transmission from larva to nymph and from larva through nymph to adult was successful; however, an experiment on transovarial transmission gave negative results. neither a americanum nor a cajennense transmitted the infection. there is a potential danger of the disease gaining access to the american mainland from the caribbean where it is known to occur and ... | 1982 | 6808870 |
| invasion of capillary endothelial cells by ehrlichia ondiri. | | 1983 | 6836885 |
| ehrlichiosis in an irish setter in mississippi: a case report. | | 1980 | 6900432 |
| cell-mediated and humoral immune responses of german shepherd dogs and beagles to experimental infection with ehrlichia canis. | the cell-mediated and the humoral immune responses of 12 german shepherd dogs and 5 beagles inoculated with ehrlichia canis were evaluated. results indicated that specific and nonspecific immunosuppression due to e canis occurred in the german shepherd dogs. canine leukocyte migration-inhibition factor was successfully isolated and shown to be physically and functionally similar to human and guinea pig migration inhibition factor. of the german shepherd dogs, 58% developed positive cell-mediated ... | 1980 | 6989300 |
| evidence of a serologic relationship between ehrlichia canis and rickettsia sennetsu. | a serologic relationship between rickettsia sennetsu, the etiologic agent of human sennetsu rickettsiosis in western japan, and ehrlichia canis, the agent of canine ehrlichiosis, has been demonstrated. using the indirect fluorescent antibody test, convalescent sera from patients with sennetsu fever reacted with ehrlichia canis antigen. in the direct fluorescent antibody test, immunoglobulins from four patients with sennetsu rickettsiosis stained e. canis morulae in canine monocytes. this finding ... | 1981 | 7034563 |
| rhipicephalus appendiculatus: cause and vector of diseases in africa. | rhipicephalus appendiculatus neum. occurs mainly in the eastern and southern parts of africa and is the principal cause and vector of some very important stock diseases in these areas. the diseases include the theilerioses, brown tick toxicosis and nairobi sheep disease. these are briefly discussed, and emphasis is laid on the role of r. appendiculatus in their epidemiology. r. appendiculatus is a 3-host tick particularly well adapted to survive where climate and vegetation are suitable. the bas ... | 1981 | 7042975 |
| distribution of ehrlichia canis among military working dogs in the world and selected civilian dogs in the united states. | antibodies to ehrlichia canis were detected by indirect immunofluorescence in sera from 233 of 2,077 (11%) military working dogs in various locations throughout the world and from 535 of 938 (57%) civilian dogs in the united states during a 1-year period of study. overall, e canis infection rates ranged from 13% in the tropical and temperate zones below 45 degrees n to 8% in the cold zone north of 45 degrees n latitude. the highest antibody prevalence rate (24%) was found among a select populati ... | 1982 | 7050062 |
| in vitro propagation of cytoecetes phagocytophila, the causative agent of tick-borne fever. | cytoecetes phagocytophila, a neutrophilic rickettsia which parasitizes sheep and cattle, was propagated transiently at 37 degrees c in cultures of heparinized whole blood of sheep supplemented with medium 199 containing hepes buffer. significant increases in the number of infected cells and the number of rickettsias per infected cell were observed within 24 h. back-passage into sheep produced typical tick-borne fever. | 1982 | 7051517 |
| infection in two dogs with an agent resembling ehrlichia equi. | | 1982 | 7061334 |
| pulmonary lesions in sheep following experimental infection by ehrlichia phagocytophilia and chlamydia psittaci. | | 1982 | 7068951 |
| a retrospective study on 120 natural cases of canine ehrlichiosis. | in a retrospective study on 120 natural cases of canine ehrlichiosis, it was found that cases were presented in all months of the year. the disease was diagnosed in 26 different breeds amongst which the german shepherd was the best represented. of the different breeds of dog, german shepherds showed the highest incidence of chronic cases as well as the highest mortality rate. in a randomly selected sample of 50 dogs, the clinical signs of canine ehrlichiosis were found to be mainly non-specific ... | 1982 | 7097704 |
| heartwater (cowdria ruminantium infection) on são tomé. | the supernatant obtained after centrifugation of an emulsion of engorged female amblyomma astrion ticks, collected from cattle on the west african island of são tomé, was injected intravenously into a goat, which contracted heartwater. this confirmation of the existence of the disease on the island makes strict control measures necessary if present efforts at improving livestock production by imported exotic cattle are to be successful. | 1982 | 7147672 |
| a comparison of the efficacy of imidocarb dipropionate and tetracycline hydrochloride in the treatment of canine ehrlichiosis. | a comparison of the efficacy of imidocarb dipropionate solution and tetracycline hydrochloride in the treatment of naturally occurring ehrlichiosis of dogs presented at the university of nairobi small animal clinic was carried out. five to 7 mg per kg imidocarb dipropionate given intramuscularly twice at an interval of 14 days was as effective as 14 daily, oral doses of 66 mg per kg tetracycline hydrochloride in alleviating the clinical signs of disease. imidocarb eliminated the infection in 81 ... | 1980 | 7210420 |
| cowdria ruminantium (rickettsiales) in primary goat kidney cell cultures. | fresh or cryopreserved kidney tissue from goats suffering from heart water (cowdria ruminantium infection) was infective when inoculated intravenously into susceptible goats. primary kidney cell cultures were established from 14 goats reacting to c ruminantium infection; they were tested for infectivity by intravenous injection into susceptible goats after periods varying from five to 31 days. three cultures, five, 12 and 13 days old, induced heartwater in recipients. the other 11 cultures, vary ... | 1980 | 7255901 |
| acute experimental canine ehrlichiosis. ii. sequential reaction of the hemic and lymphoreticular system of selectively immunosuppressed dogs. | the lymphoreticular response of dogs to ehrlichia canis infection was studied after immunosuppressive therapy with cyclophosphamide or antilymphocyte serum. immunosuppression did not increase mortality, nor did it prevent or significantly modify the clinical manifestations of acute ehrlichiosis. the clinical, hematologic and serum biochemical characteristics of acute ehrlichiosis appeared seven or more days later in immunosuppressed than in immunologically intact infected dogs. immunosuppressive ... | 1981 | 7257081 |
| some effects of 60co irradiation on cowdria ruminantium in its tick host amblyomma hebraeum koch (acarina: ixodidae). | an attempt was made to attenuate cowdria ruminantium by irradiation of the nymphal stage of its tick host, amblyomma hebraeum. the irradiated nymphs were homogenized and serial dilutions of the resultant suspension were injected intravenously into heartwater-susceptible sheep. no attenuation could be demonstrated but the results indicate that progressively more micro-organisms will be destroyed the higher the irradiation dosage applied, and that dosages between 20 and 30 kilorad apparently prove ... | 1981 | 7279384 |
| heartwater: cross-immunity studies with strains of cowdria ruminantium isolated in west and south africa. | | 1981 | 7292612 |
| attempted treatment of canine ehrlichiosis with imidocarb dipropionate. | six clinical and 10 experimentally-induced cases of canine ehrlichiosis were treated with imidocarb dipropionate. the treatment did not result in clinical cure and failed to sterilize the infection. the infection was successfully transmitted from treated dogs to splenectomized and non-splenectomized dogs. | 1981 | 7310786 |
| oxytetracycline plasma levels in dogs after intramuscular administration of two formulations. | plasma levels of oxytetracycline in dogs were compared in a cross-over study. a long-acting formulation and a polyvinylpyrrolidone formulation were injected intramuscularly. symptoms of histamine release were recorded after the use of polyvinylpyrrolidone formulation. higher peak plasma concentrations but shorter maintenance of therapeutic concentrations were recorded in the case of the polyvinylpyrrolidone formulation than with the long-acting formulation. | 1981 | 7310789 |
| attempted transmission of canine ehrlichiosis to the vervet monkey (cercopithecus pygerythrus). | blood from a domestic dog infected with ehrlichia canis was injected into 3 adult vervet monkeys cercopithecus pygerythrus. the monkeys did not develop any clinical or haematological signs of disease, nor did they seem to be able to harbour the parasite. furthermore, neither morulae of e. canis nor haematological evidence of ehrlichiosis were seen after these monkeys had been splenectomized. the splenectomized monkeys did, however, develop a severe parasitaemia of their red cells with entopolypo ... | 1981 | 7312306 |
| experiences with the use of imizol in treating canine blood parasites in nigeria. | | 1981 | 7339205 |
| [a new rickettsiale (ehrlichiae) in leukocytes of the blood of gambia rats (cricetomys gambianus) in senegal : cytoecetes kamtchoulii n. sp]. | among 20 hemograms (peripheric blood smears) carried out upon some adults male and female giant rats, (cricetomys gambianus) captured in the dakar region, two (10 p. 100) are infected by one rickettsiale of the ehrlichiae tribe and of the cytoecetes genus tyzzer, 1938. polymorphonuclear neutrophil leukocytes and monocytes, more or less 1/25, and monocytes, more or less 1/40, of the systemic circulation are infected by "elementary bodies" (diameter : 0.1 to 0.3 mu) included in the cell protoplasm ... | 1981 | 7346908 |
| a simple technique for the collection of brain samples for the diagnosis of heartwater. | a simple technique for the collection of brain samples for the post-mortem diagnosis of heartwater (cowdria ruminantium infection) is described. a sharp spoon (curette) or teaspoon and a knife are the only instruments required. after the head has been removed from the body a sample of cerebellar cortex is collected with the spoon through the foramen occipitale, thus obviating the need for opening the skull itself. this diagnostic technique appears to be as reliable as the convenient technique of ... | 1980 | 7368317 |
| serial propagation of ehrlichia canis in primary canine peripheral blood monocyte cultures. | cultures of primary canine monocytes were prepared from blood to which dextran (3%) had been added to enhance sedimentation of the erythrocytes. homogeneous populations of monocytes were observed by 5 days after seeding, and some cultures were maintained as long as 30 days. the monocyte cultures were used successfully for the serial passage of ehrlichia canis. after the 3rd passage, small intracytoplasmic inclusions of e canis were detected by 60 hrs after inoculation and greater than 90% of the ... | 1980 | 7379552 |
| the effects of tick-borne fever (ehrlichia phagocytophilia) on the growth rate of fattening cattle. | | 1980 | 7407538 |
| canine ehrlichiosis. | | 1980 | 7440320 |
| serum complement and blood platelet adhesiveness in acute canine ehrlichiosis. | three dogs inoculated with ehrlichia canis served as infected controls (group i), 3 dogs treated with cobra venom factor (cvf) after inoculation with e canis were the principals (group ii), 3 noninfected dogs were the noninfected controls (group iii), and 1 noninfected dog given cvf was the noninfected, decomplemented control (group iv). thrombocytopenia occurred in all e. canis-inoculated dogs (groups i and ii) within 3 weeks after they were inoculated. however, the severity of the thrombocytop ... | 1980 | 7447122 |
| [cowdriosis (heartwater) by cowdria ruminantium in ruminants of french indies (guadeloupe) and mascarene islands (la reunion and mauritius)]. | | 1980 | 7455277 |
| free-living jackals (canis mesomelas)-potential reservoir hosts for ehrlichia canis in kenya. | using a modified cell culture test, ehrlichia canis was found in eight of 15 free-living jackals (canis mesomelas) and 14 of 31 dogs owned by pastoral communities in the same areas of kenya. two cross-bred puppies inoculated with blood from infected jackals developed mild, transient clinical disease, and e. canis was recovered from the puppies. tick species found on the jackals were similar to those found on the infected dogs. ehrlichia canis was not found in eight spotted hyaenas (crocuta crocu ... | 1980 | 7463598 |
| acute experimental canine ehrlichiosis. i. sequential reaction of the hemic and lymphoreticular systems. | dogs with acute ehrlichia canis infection showed the established clinical features of acute ehrlichiosis and had thrombocytopenia, anemia, increased serum glutamic pyruvic transaminase activity, and decreased total serum protein and albumin concentrations during the first weeks after infection, and increasing gamma globulin concentrations after the third week. gross lesions in hemic and lymphoreticular tissues were transient lymphadenomegaly, splenomegaly, and increased red long-bone marrow. lym ... | 1981 | 7467072 |
| ultrastructural variation of cultured ehrlichia chaffeensis. | the ultrastructure of ehrlichia chaffeensis (arkansas strain) was studied in non-irradiated and irradiated monolayers of mouse embryo, vero, bgm and l929 cells, and in non-irradiated dh82 cells. within the intracellular parasitophorous vacuoles (morulae), two types of ehrlichial cells were found regularly--those with uniformly dispersed nucleoid filaments and ribosomes (dense-cored cells), which represent the normal life cycle of ehrlichiae. in addition, large reticulate cells were observed, for ... | 1995 | 7473674 |
| ehrlichiosis in belgium. | | 1995 | 7475691 |
| human ehrlichiosis in a liver transplant recipient. | | 1995 | 7482752 |
| evidence for a high rate of false-positive results with the indirect fluorescent antibody test for ehrlichia risticii antibody in horses. | the original objective was to determine seroprevalence of ehrlichia risticii antibody among horses in california. on the basis of the unexpected results of the survey, an investigation into the accuracy and reproducibility of results of the indirect fluorescent antibody (ifa) test for e risticii was carried out. | 1995 | 7493874 |
| use of a specific immunogenic region on the cowdria ruminantium map1 protein in a serological assay. | currently available serological tests for cowdriosis (cowdria ruminantium infection) in domestic ruminants are hampered by their low specificities because of cross-reactivity with ehrlichia spp. the use of recombinant major antigenic protein (map1) of c. ruminantium for serodiagnosis was investigated. overlapping fragments of the map1 protein were expressed in escherichia coli and were reacted with sera from sheep infected with either c. ruminantium or ehrlichia ovina. two immunogenic regions on ... | 1995 | 7494037 |
| detection of cowdria ruminantium in blood and bone marrow samples from clinically normal, free-ranging zimbabwean wild ungulates. | cowdria ruminantium causes severe, often fatal disease in domestic ruminants, whereas wildlife species usually are not affected. blood and bone marrow samples from healthy, free-ranging zimbabwean ungulates were taken during translocation from areas harboring amblyomma ticks and tested for the presence of c. ruminantium, using a pcr assay based on the c. ruminantium map1 gene. positive reactions were obtained in tsessebe (damaliscus lunatus), waterbuck (kobus ellipsiprymnus), and impala (aepycer ... | 1995 | 7494060 |
| the cowdria ruminantium groe operon. | a cowdria ruminantium genomic dna library was constructed in the expression vector lambda zapii, and an immunoreactive clone, designated lambda cr9.4, was isolated by screening with serum from a c. ruminantium-infected goat. sequencing of the insert from this clone revealed two open reading frames, encoding peptides of 10462 and 58697 kda respectively. database searching indicated that the two genes were homologues of groes and groel, genes encoding a group of heat shock proteins involved in pro ... | 1995 | 7496520 |
| the detection of antibodies cross-reacting with cowdria ruminantium in the sera of domestic ruminants in regions of south africa where amblyomma hebraeum does not occur. | high levels of seropositivity, in all probability attributable to ehrlichia, were recorded in the serum of domestic ruminants throughout districts in south africa where amblyomma hebraeum, the vector of the heartwater agent, does not occur. the antibodies, detected with the indirect fluorescent antibody (ifa) and the indirect elisa tests, cross-reacted with cowdria ruminantium, which was used as antigen in both tests. a combination of the ifa and elisa tests, currently employed to detect antibod ... | 1994 | 7501358 |
| effects of tick infestation and tick-borne disease infections (heartwater, anaplasmosis and babesiosis) on the lactation and weight gain of mashona cattle in south-eastern zimbabwe. | the effects of ticks and tick-borne disease infections on the lactation and weight gain of mashona cattle were studied at mbizi quarantine station in the south-eastern lowveld of zimbabwe. twenty-nine mashona cows were allocated to 2 balanced groups and kept in separate paddocks at a stocking rate of one animal per 8 ha. one group received regular acaricide treatment to control bont (amblyomma hebraeum) and other ticks. the other group was left untreated. the cows were artificially inseminated. ... | 1995 | 7502343 |
| detection of ehrlichia chaffeensis in human tissue by using a species-specific monoclonal antibody. | a mouse monoclonal antibody (mab 1a9) was produced and used in detection of ehrlichia chaffeensis in human tissues including kidney, liver, and lung by using an indirect immunohistologic stain. mab 1a9 was specific to e. chaffeensis and did not react with other bacteria, including ehrlichia canis, which is the organism most closely related to e. chaffeensis. it reacted with an epitope present in two surface proteins of e. chaffeensis with molecular masses of 29 and 27 kda. e. chaffeensis was eas ... | 1993 | 7508458 |
| role of interferons in infectious diseases in the bovine species: effect on viruses and rickettsias. | successful protection was obtained with interferon treatment in experimental viral infections in the bovine species in a number of cases. the efficacy of the treatment against vaccinia virus infection and against rotavirus infection have been demonstrated. on the contrary, bovine herpes virus 1 (bhv 1-causing rhinotracheitis and part of the shipping fever complex) infections were not inhibited by interferon (ifn). the authors have undertaken a study in cattle in zimbabwe to assess the role of in ... | 1993 | 7510899 |
| detection of mip-like sequences and mip-related proteins within the family rickettsiaceae. | the mip surface protein, a prokaryotic analog of the fk506-binding proteins, enhances the ability of legionella pneumophila to infect macrophages and protozoa. using mip-specific probes and low-stringency southern hybridizations, we have detected dna sequences homologous to mip within coxiella burnetii and rochalimaea quintana. using specific anti-mip antisera and immunoblot analysis, we also detected mip-related proteins within these bacteria as well as within rickettsia and ehrlichia species. ... | 1995 | 7532505 |
| antigenic, morphologic, and molecular characterization of new ehrlichia risticii isolates. | ehrlichia risticii causes an acute infectious disease in horses called potomac horse fever. to investigate the biological diversity of e. risticii organisms, nine e. risticii isolates derived from the peripheral blood monocytes of clinically sick horses in ohio and kentucky during the summers of 1991 and 1993 were compared with illinois and virginia isolates originally obtained from horses in maryland in 1984. seven of the nine isolates (081, 606, 380, 679, as, co, and ov) formed large morulae ( ... | 1994 | 7533780 |
| 16s rrna gene sequence of neorickettsia helminthoeca and its phylogenetic alignment with members of the genus ehrlichia. | neorickettsia helminthoeca (tribe ehrlichieae, family rickettsiaceae) is the agent of salmon poisoning disease, which affects members of the family canidae. this bacterium is unusual in that it is the only known obligately intracellular bacterium that is transmitted via a helminth vector. the nucleotide sequence of the n. helminthoeca 16s rrna gene was determined and compared with the sequences of intracellular bacteria belonging to the alpha subgroup of the proteobacteria. the n. helminthoeca s ... | 1995 | 7537055 |
| ehrlichia muris sp. nov., identified on the basis of 16s rrna base sequences and serological, morphological, and biological characteristics. | the 16s rrna gene of a new infectious agent, strain as145t (t = type strain), which was isolated from a wild mouse in japan, was amplified by using the pcr. the amplimers were directly sequenced by dideoxynucleotide methods with taq dna polymerase. sequence comparisons with other members of the tribe ehrlichieae and related species revealed that the infectious agent isolated from the mouse is a new species of the genus ehrlichia that is most closely related to ehrlichia chaffeensis (level of seq ... | 1995 | 7537059 |
| diversity of 16s rrna genes of new ehrlichia strains isolated from horses with clinical signs of potomac horse fever. | ehrlichia risticii is the causative agent of potomac horse fever. variations among the major antigens of different local e. risticii strains have been detected previously. to further assess genetic variability in this species or species complex, the sequences of the 16s rrna genes of several isolates obtained from sick horses diagnosed as having potomac horse fever were determined. the sequences of six isolates obtained from ohio and three isolates obtained from kentucky were amplified by pcr. t ... | 1995 | 7537065 |
| identification of the causative agent of granulocytic ehrlichiosis in swedish dogs and horses by direct solid phase sequencing of pcr products from the 16s rrna gene. | seven swedish isolates of ehrlichia species from the blood of four dogs and three horses with clinical granulocytic ehrlichiosis, were identified by direct solid phase dna sequencing of polymerase chain reaction (pcr) products from the 16s rrna gene. the amplified dna fragments were produced with primers complementary to the universal regions, u1, u2, u5 and u8 of the 16s rrna molecule. identical sequences were obtained from all seven isolates. this nucleotide sequence was similar to the sequenc ... | 1995 | 7539151 |