Publications

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b-cell activation in angioimmunoblastic lymphadenopathy after immunisation with multivalent pneumococcal polysaccharide vaccine. 197991879
effect of uv on cleavage of xenopus laevis.uv irradiation of the vegetal pole of stage 2 x. laevis embryos with doses of 6000-18000 ergs/mm-2 delayed or inhibited cytokinesis in the vegetal hemisphere. nuclear division continued so that a syncytium was formed, the size and persistence of which depended on the dose. embryos which received a low uv dose were subsequently able to recover whereas embryos receiving a high dose were unable to gastrulate successfully. the implications for investigations into the role of cytoplasmic determinants ...19751133572
antibody mediated enhancement of hiv-1 infection of an ebv transformed b cell line is cd4 dependent.low levels of anti-viral antibodies may facilitate virus infection of fc-receptor bearing cells. for human immunodeficiency virus (hiv) it has been reported that antibodies can enhance infection of phagocytic cells. we show that hiv-1 can infect an epstein-barr virus transformed b cell line and that low levels of anti-hiv antibodies enhance infection. the enhanced infection was characterized by an increase in viral dna and increased hiv p24 protein production. detection of cell surface antigen e ...19921459171
tannin mediated alveolar macrophage protein phosphorylation.experiments were designed to determine if cotton bract tannin, a component of cotton mill dust, would promote the phosphorylation of alveolar macrophage proteins in doses potentially achievable in vivo. rabbit alveolar macrophages were loaded with 32po4 and challenged with various doses of tannin for time periods ranging from two seconds to 120 minutes. changes in protein phosphorylation began after two seconds and were maximal at five to fifteen minutes. dose response studies using an exposure ...19892505060
cmv, hiv, and the pancreas. 19882901600
change in collagen synthesis of human chondrocyte culture. i. development of a human model, demonstration of collagen type conversion by immunofluorescence.a research system constituted entirely of components of human origin was developed to study conversion of collagen synthesis by human chondrocytes. type specificity of affinity chromatography-purified antibodies to human type ii or type i collagen was proven by elisa inhibition and immunofluorescence analysis. human chondrocytes were isolated from articular cartilage and kept in monolayer cultures for eight subpassages. conversion of type ii to type i synthesis by chondrocytes was investigated b ...19863532286
change in collagen synthesis of human chondrocyte culture. i. development of a human model, demonstration of collagen type conversion by immunofluorescence.a research system constituted entirely of components of human origin was developed to study conversion of collagen synthesis by human chondrocytes. type specificity of affinity chromatography-purified antibodies to human type ii or type i collagen was proven by elisa inhibition and immunofluorescence analysis. human chondrocytes were isolated from articular cartilage and kept in monolayer cultures for eight subpassages. conversion of type ii to type i synthesis by chondrocytes was investigated b ...19863532286
[electron microscopic studies of the islands of langerhans in the rat. the b cell and the capillaries]. 19863543383
canine thymoma.thymoma is an uncommon canine neoplasm of thymic epithelial cells. it is seen in various breeds but may occur more frequently in german shepherd dogs. middle-aged or older dogs can be affected and no sex predilection exists. a paraneoplastic syndrome of myasthenia gravis, nonthymic malignant tumors, and/or polymyositis occurs in a significant number of dogs with thymoma. clinical signs are variable and are related to a space-occupying cranial mediastinal mass and/or manifestations of the paraneo ...19853898533
a mr 90 000 surface polypeptide of trypanosoma cruzi as a candidate for a chagas' disease diagnostic antigen.trypanosoma cruzi (peru strain) trypomastigotes and epimastigotes were biosynthetically labeled with [35s]methionine, and the proteins were analyzed by two dimensional polyacrylamide gel electrophoresis (2d-page). 2d-page analysis of the trypomastigotes showed a complex array of polypeptides with distinct clusters at mr 88 000-92 000, isoelectric point (pi) 5.6-6.0, and mr 72 000-76 000, pi 5.6-5.8. 2d-page analysis of the epimastigotes did not show the cluster of polypeptides at mr 90 000. when ...19853932849
comparison of adenosinetriphosphatase activity in testicular and ejaculated spermatozoa of the ram. 19694257069
comparison of adenosinetriphosphatase activity in testicular and ejaculated spermatozoa of the ram. 19694257069
inhibition by formaldehyde of energy transfer and related processes in rat liver mitochondria. ii. effects on energy-linked reactions in intact mitochondria and phosphorylating particles. 19694307346
[nucleolus fusion and acrocentric chromosome associations in human cells]. 19744432287
[how the length of bacterial flagella is determined in vitro? (author's transl)]. 19734582327
perturbation of red cell volume. determination of membrane transport parameters for rapid penetrants. 19724640766
primary large cell lymphoma of the rectum. 20061489301
[biochemical effects of continuous and discontinuous muscular work (interval work)]. 20164720306
[biochemical effects of continuous and discontinuous muscular work (interval work)]. 20164720306
[determination of the impaired ear's frequency selectivity using psychoacoustical tuning curves (author's transl)].an apparatus for clinical use is described by which simplified psychoacoustical tuning curves can be measured near 500 hz and near 4 khz. data produced by four groups (normal hearing, conductive hearing loss, noise induced hearing loss and degenerative hearing loss) are separately averaged and compared. the first mentioned two groups as well as the third in the low frequency range show good frequency resolution, the others, however, show largely decreased frequency resolution.2002139511
overdose with baclofen. 20143945841
[characteristics of pulmonary manifestations of mycosis fungoides]. 20061803158
insensitivity, limited joint mobility, and plantar ulcers in patients with diabetes mellitus.the purpose of this study was to determine whether differences in sensation, ankle dorsiflexion (df), and subtalar joint (stj) motion exist between 1) diabetic patients with a history of plantar ulcer (dmw group), 2) diabetic patients without a history of plantar ulcer (dmwo group), and 3) a nondiabetic control group (ndc group). there were 23, 23, and 24 subjects in the respective groups. the mean age for each group was 58, 63, and 60 years, respectively. the mean df for each group was 2, 5, an ...20092727069
absence of species specificity of the kcl factor in the cell free synthesis of hemoglobin. 19724646819
colon polyps and carcinomas: prospective comparison of the single- and double-contrast examination in the same patients.single-contrast (sc) and double-contrast (dc) colon examinations were compared in 425 consecutive patients for detection of polyps and stricturing carcinomas. each patient was examined with both sc and dc during the same session. in patients with carcinoma, there was no significant difference between the two modalities. dc was far superior to sc for detection of rectal or colonic polyps (p less than 0.05); however, the techniques appeared to be complementary in the sigmoid and cecum. the authors ...20113964926
go-left go-right discrimination performance and distractibility following lesions of prefrontal cortex or superior colliculus in stumptail macaques. 200199682
a realistic approach to the application of the concepts of morris & bohannan (1985). 20123461044
[changes in the face, jaw and tooth structures following treatment of scoliosis with a milwaukee brace]. 20154534486
[the effects of 1,3-dioxolane derivative (esperan) on the smooth muscle and its intrinsic nerves of guinea-pig stomach (author's transl)]. 19744471926
determination of the dissociation constant of oligomeric proteins by size-exclusion high-performance liquid chromatography: application to human haemoglobin.the measurement of protein retention volumes on a size-exclusion chromatographic column offers the possibility of determining dissociation constants for oligomeric proteins, as changes in the retention volume, depending on the concentration of the protein, are due to a dissociation equilibrium. the retention volume may be calibrated in terms of dissociation constant by using either extreme concentration conditions or chemical modifications that shift the equilibrium towards a single species. whe ...19854030962
wound management following head and neck surgery: the challenge of complex nursing intervention. 199993742
a controlled study of the analgetic effect of two non-steroidal anti-inflammatory drugs in cancer pain.with a subjective response technique the analgetic activity of two non-steroidal anti-inflammatory agents which greatly differ in kinetics is compared. the double-blind cross-over trial was carried out in 18 patients of both sexes suffering from pain due to malignant tumours who received single doses of 200 mg indoprofen and 250 mg naproxen p.o. both compounds were efficacious and there was no difference in the duration of their activity in spite of the great difference between their half-lives.2004383108
pathology of squamous carcinomas of the head and neck. 20071892919
[dynamics of calving, dystocia and the organization and effectiveness of obstetrical care for cows on commercial farm complexes].a study was carried out on the organization of the obstetrical aid with cows on the large cow complexes in order to raise its effectiveness. determined was the dynamic of calvings, dystocia, retentio secundinarum, and puerperal endometritis as affected by the time of calving and the character of obstetrical aid as practised on the farms. it was found that most of the calvings (62.6 per cent) take place at night, and 37.4 per cent--in daytime, while within the working day as fixed by the labour c ...19863811210
linear relationship between valinomycin-created membrane polarization in egg-lecithin vesicles and fluorescence change by merocyanine 540 [proceedings]. 200092259
[micromethod of determining antibodies to nerve tissue galactocerebrosides in the complement fixation reaction].a micromethod has been developed for the determination of serum antibodies to galactocerebroside, a specific antigen of myelin membranes. the method is based on complement fixation test and is used for the analysis of sera from healthy rabbits and those immunized with galactocerebroside.19873689976
gordon memorial lecture. poultry disease and public health.the development of the poultry industry and the consumption of poultry meat is traced over the past quarter of a century and related to the increased incidence of food poisoning in man. factors affecting the spread of the main poultry pathogens which are of human significance are discussed. the pathogens considered are salmonella, campylobacter, staphylococci and clostridia. various preventative measures are considered including rearing procedures for poultry, decontamination methods and educati ...19873567687
identification and localization of 7b2 protein in human, porcine, and rat thyroid gland and in human medullary carcinoma.the novel, highly conserved polypeptide 7b2, which belongs to a new protein superfamily, was isolated from human and porcine hypophysis. the availability of a specific antibody to a synthetic fragment enabled 7b2 localization in a number of neurocrine and endocrine tissues and revealed its secretory character. 7b2 was purified from thyroid homogenates by hplc chromatography and characterized by gel permeation chromatography (dimeric mol wt, approximately 40,000) and sodium dodecyl sulfate-polyac ...19883293987
identification and localization of 7b2 protein in human, porcine, and rat thyroid gland and in human medullary carcinoma.the novel, highly conserved polypeptide 7b2, which belongs to a new protein superfamily, was isolated from human and porcine hypophysis. the availability of a specific antibody to a synthetic fragment enabled 7b2 localization in a number of neurocrine and endocrine tissues and revealed its secretory character. 7b2 was purified from thyroid homogenates by hplc chromatography and characterized by gel permeation chromatography (dimeric mol wt, approximately 40,000) and sodium dodecyl sulfate-polyac ...19883293987
non-immune igg f(ab')2 binding to group c and g streptococci is mediated by structures on gamma chains.the present investigation was designed to determine whether the heavy or the light immunoglobulin chain is involved in the non-immune binding of igg f(ab')2 fragments to specific surface receptors on human group c and g streptococci. purified human polyclonal igg was mildly reduced with dithiothreitol and alkylated with iodoacetamide. light (l) and heavy (h) chains were separated. intact igg and purified l and h chains of polyclonal immunoglobulin g were tested in an inhibition assay for non-imm ...19853156400
comparative study of c5a plasma levels with different hemodialysis membranes using an enzyme-linked immunosorbent assay.using a specific and sensitive elisa for c5a, the present study shows that predialysis levels of c5a in end-stage renal disease patients are not elevated and that all membranes studied (cuprophan, hemophan, gambrane and hydrophilic polysulfone) cause significant increases of c5a plasma levels albeit to different degrees. higher increases of c5a were accompanied by larger decreases of circulating granulocytes and monocytes. dialyzers with a newly introduced modified regenerated cellulose membrane ...20102918943
haemorrhagic shock encephalopathic syndrome and neurodevelopmental delay. 20102863462
urethritis caused by neisseria meningitidis group b: a case report.we describe a case of acute urethritis caused by neisseria meningitidis group b in a heterosexual man. the symptoms started five days after intercourse that included fellatio with a casual female partner. no other urethral pathogens could be isolated. after intramuscular administration of penicillin g, clinical signs and symptoms of urethritis disappeared, and despite repeated attempts, n. meningitidis could no longer be isolated from the urethra. this case illustrates the need for careful diagn ...19883147520
[value of microscopic detection of acid fast rods in tuberculosis of the middle ear].the microscopic identification of acid-proof rod-shaped bacilli via smear is of great importance for the diagnosis of tuberculous otitis media, since it is performed quickly and easily, for it enables an early diagnosis and treatment. the importance of the staining method using auramine is discussed, and it is examined if contamination by apathogenic or atypic mycobacteriae can yield a wrong positive result.19863083165
effects of electrical stimulation and choline availability on the release and contents of acetylcholine and choline in superfused slices from rat striatum.the presence of 5 or 20 microm choline in the eserinized medium superfusing striatal slices enhanced the spontaneous release of acetylcholine (ach) at both concentrations and, at 20 microm, the release of transmitter evoked by electrical field stimulation. neither the electrical stimulation nor the addition of choline altered choline acetyltransferase activity. these results show that ach release is dependent on the availability of extracellular choline. the rate of choline efflux was 7 times hi ...19853003350
studies on the effect of glycoprotein processing inhibitors on fusion of l6 myoblast cell lines.the effect of oligosaccharide processing inhibitors on the fusion of l6 myoblasts was studied. the glucosidase inhibitors, castanospermine, 1-deoxynojirimycin and n-methyl-deoxynojirimycin were potent inhibitors of myoblast fusion, as was the mannosidase ii inhibitor, swainsonine. inhibition of fusion was reversed when inhibitors were removed. however, the mannosidase i inhibitor, 1-deoxymannojirimycin did not inhibit fusion. changes in cell membrane oligosaccharide structure were followed by mo ...19872946596
changes in the dopaminergic control of prolactin secretion and in ovarian steroids in migraine.prolactin (prl) responses to dopamine (da) blockers and to direct and indirect da agonists have been studied in 23 healthy women, 17 women with catamenial migraine and 17 with non-catamenial migraine in both their follicular and luteal phases. prl responses to the da blockers were greater in the follicular phase of both migraine groups than in controls. the inhibitory effect of nomifensine on prl secretion was dampened in the follicular phase of both migraine groups. these findings demonstrate a ...20133698093
new drug for induction of ovulation. 20154481167
detection of recombination events in human cells using cloned cytomegalovirus dna fragments as probes.a method is presented for the detection of virus-host interactions at the chromosomal level. this method relies on the analysis of recombinant plasmids carrying specific regions of a viral dna molecule. human cytomegalovirus hindiii subgenomic fragments were used here as a target for recombination events.19882847965
investigation of the biochemical state of paramagnetic ions in vivo using the magnetic field dependence of 1/t1 of tissue protons (nmrd profile): applications to contrast agents for magnetic resonance imaging. 19882832351
thermogenic and hormonal responses to palatable protein and carbohydrate rich food.simultaneous variations of oxygen consumption, and plasma insulin and norepinephrine were measured during the postprandial cephalic and gastrointestinal phases of feeding in six human subjects following the ingestion of various nutrients. on alternative days the subjects were given foods (1280 kjoules) either rich in carbohydrates (sugar pie) or in proteins (fish). both nutrients produced an initial (0-40 min) enhanced thermogenesis and an early (2 min) cephalic insulin release. during that peri ...19911774019
characterization of a pollen-specific cdna from sunflower encoding a zinc finger protein.we have isolated, via differential hybridization screening of a floral cdna library from sunflower, a cdna clone that hybridizes to a 1100 nucleotide-long mrna found exclusively in mature pollen grains. the cdna encodes a 219 amino acid-long polypeptide containing two potential zinc fingers alternating with two basic domains. a similar organization is found in the erythroid-specific transcription factor eryf1 from chicken and its murine homolog gf-1. the c-terminus of the protein contains a sixf ...19921302629
cellular and free lipopolysaccharides of some species of neisseria.cultures of eight non-pathogenic species of neisseria grown in simple defined media released lipopolysaccharide (free lipopolysaccharide) by a process distinct from cellular autolysis. analyses of the pure cellular and free lipopolysaccharides obtained from six species of neisseria revealed that they were remarkably similar and were devoid of detectable o-antigen side chains. three distinct types of core-oligosaccharides were demonstrated. type i core-oligosaccharide was a branched structure of ...19751220863
difference in the effect of glucagon and starvation upon l-type pyruvate kinase from rat liver. 1978216548
[protection by oral vaccination of mice with an avirulent live strain of salmonella typhimurium].before determining the quantity of mouse intestinal secretory iga after oral vaccination, we have tried to find the best conditions of immunization with an avirulent s. typhimurium strain given by oral route. the results show the superiority of the live vaccin with respect to the heat-killed one.1975126768
the isolation and partial characterization of the serum lipoproteins and apolipoproteins of the rainbow trout.1. vld (very-low-density), ld (low-density) and hd (high-density) lipoproteins were isolated from the serum of trout (salmo gairdneri richardson). 2. each lipoprotein class resembled that of the human in immunological reactivity, electrophoretic behaviour and appearance in the electron microscope. trout ld lipoprotein, however, was of greater density than human ld lipoprotein. 3. the trout lipoproteins have lipid compositions which are similar to those of the corresponding human components, exce ...1978100102
[effectiveness of a preventive mass examination for cardiac risk factors (author's transl)].18 months after a mass examination for coronary heart disease risk factors in employees of a large industrial firm, 75% of the subjects examined at that time were re-interviewed and measurements of blood pressure and weight repeated. despite an altogether inadequate longterm control of the risk factors detected, a part of the subjects examined had drawn consequences regarding their way of life by reducing weight, changing smoking habits and increasing physical activity, thus proving the effectiv ...1998107409
evaluation of the nottingham birth scoring system.a case-control study of postneonatal deaths occurring in 1974-1976 in the city of nottingham, england, revealed that most were attributable to respiratory infections and sids, and primarily occurred in wintertime, at home, in the less well-off parts of nottingham. by means of a step-wise discriminant analysis, 9% of the infant population was identified as a high-risk group in whom 53% of postneonatal deaths could be expected to occur. from january 1, 1978, this group of infants was followed up m ...20123421617
[weakness of the public health services as reflected in the suicide intervention by telephone]. 20154498597
[a micromethod of paper-chromatography of amino acids]. 20164720323
total parenteral nutrition. 1998107267
gut size and the digestion of fibrous diets by tetraonid birds.a series of diets containing different proportions of heather was fed to red grouse. heather is the bird's main natural food and contains much fiber; the rest of each diet was a relatively low-fiber, grain-based formulation. with increasing heather and associated fiber contents, food intake increased and overall digestibility of heather was only 9.4%, but, when heather was eaten as the sole food by wild red grouse, its digestibility was 46%. adaptations to diets containing more heather included ...20082575129
immunotherapy in bladder cancer with keyhole-limpet hemocyanin: a randomized study.a randomized, controlled study was begun in 1982 on the effect of keyhole-limpet hemocyanin and mitomycin c in the prevention of recurrent superficial bladder cancer (stages pta to pt1, grades 0 to 3) in 44 patients. all tumors were resected and all patients were presumed to be free of tumor at initiation of the prophylactic instillations. before the bladder instillation program was begun all patients in the keyhole-limpet hemocyanin group ia were immunized with 1 mg. keyhole-limpet hemocyanin i ...20113127600
traumatic closed iliac bone biopsy defect simulating involvement by hodgkin's disease.a case is presented in which post biopsy changes in the iliac bone following traumatic closed biopsy resembled hodgkin's disease radiographically and with computed tomography.20123409199
proceedings: parasitic arterial supply to renal carcinoma. 19971218320
anatomical and physiological characteristics to predict football ability at the university of arkansas. 2001145429
[automobile traumatism and its prevention]. 2002126405
initial management of pediatric head trauma.head injuries are the most common cause of disability and death in children. identification of children who require specialized management following a head injury will reduce the associated morbidity and mortality. thus, it is important to differentiate the child who can be safely observed and who will recover spontaneously from the child who will develop a progressive neurologic deficit from a treatable cause. a thorough history, a tailored neurologic examination and limited radiographic studie ...20061595512
infection control in the intensive care unit. 20061483021
regulation of fructose 2,6-bisphosphate levels in neurospora crassa.both wild type and cr-1 mutant (adenylate cyclase and cyclic amp-deficient) strains of neurospora crassa contain fructose 2,6-bisphosphate at levels of 27 nmol/g dry tissue weight. this level decreases by about 50% in both strains upon depriving the cells of carbon or nitrogen sources for 3 h. an increase in cyclic amp levels produced by addition of lysine to nitrogen-starved cells produced no increase in fructose 2,6-bisphosphate levels. both strains respond to short-term addition of salicylate ...20083040112
lithium gastrointestinal diffusion system: method of preparation. 20113438339
methemoglobinemia due to occupational exposure to dinitrobenzene--ohio, 1986. 20113131654
assessing cardiac function by gas exchange.exercise stresses the primary function of the cardiovascular system, which is the supply of o2 and removal of co2 from the cells of the body. even ordinary walking requires an increase in o2 consumption and co2 production by the exercising muscles of 20 times the resting level. while pulmonary dysfunction may affect arterial blood gas tensions, the dynamics of o2 uptake and co2 output by the lungs depend on the circulatory responses to exercise. thus, measurement of the dynamics of o2 uptake in ...20113048668
[aids--even children are affected]. 20133807478
[demonstration and reaction of 2-ethoxy-3-acetoacetyl-chinoxaline. 42. studies on 4-pyrones]. 20164730141
on the amount of (na+ + k+)-atpase available for transepithelial sodium ion transport in the amphibian skin.pretreatment of frog skin epithelium homogenates with sodium dodecyl sulphate in the presence of atp reveals levels of ouabain-sensitive atpase activity usually higher and occasionally far higher than those required to sustain maximum rates of na+ transport. this supports the view that na+ transport involves only a fraction of the epithelial cells.2002134748
the relationship between renal metabolism and proximal tubule transport during ontogeny.the proximal tubules of newborn and adult animals reabsorb a similar fraction of the filtered load of na+ and h2o (65%-70%). in tubules from adult animals, transcellular, active na+ reabsorption accounts for one-third of the total, while two-thirds occur passively through the paracellular pathway, driven by hydrostatic and oncotic forces (one-third) and by cell-generated effective osmotic and ionic gradients (one-third). since two-thirds of the na+ is reabsorbed passively and does not require en ...20113153041
dermatofibrosarcoma protuberans of the vulva.a woman aged 52 years had a tumor of the mons pubis. the morphologic picture, featuring a whirling of spindle cells with long slender, interdigitating cell processes and so-called labyrinth nuclei, conformed to a dermatofibrosarcoma protuberans. wide local excision is sufficient therapy, but more experience with this rare sarcoma of the vulva is necessary.20133965375
[the state of non-specific immunologic reactivity in healthy preschool and school children]. 20154642505
study concerning the relation between the level of csf lactic acid and the clinical, eeg and rheoencephalographic data in patients with ischemic cerebrovascular disease. 20154758237
[my experience in tanzania]. 20113130634
fractures of the medial orbital wall.two cases of patients with isolated medial orbital wall fractures are described. presenting physical findings were minimal; however, both patients were noted to have bleeding into the nasopharynx from unidentified sources. routine radiographs failed to disclose the fractures, which were clearly shown by computed tomography. reconstructive surgery was planned for one patient. frequently overlooked, this injury may be the cause of delayed enophthalmos, meningitis, or blindness. the presentation, d ...20123415069
asthma mortality: a review of recent experience in new zealand. 20133624683
study concerning the relation between the level of csf lactic acid and the clinical, eeg and rheoencephalographic data in patients with ischemic cerebrovascular disease. 20154758237
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