PMID(sorted ascending)
systemic or local treatment of erythrasma? a comparison between erythromycin tablets and fucidin cream in general a danish multi-practice study the efficacy of erythromycin tablets (abboticin 500 mg tablets), fusidic acid cream (fucidin cream), and placebo was compared in 86 patients (71 men and 15 women) with erythrasma. the patients were treated 'double-blind' for 14 days with either active tablets + placebo cream, placebo tablets + active cream, or placebo tablets + placebo cream. the signs of erythrasma, i.e. colour intensity, demarcation, and scaling of the affected area, as well as degree of fluore ...20072041927
alcohol and drug use, family situation and school performance in adolescent children of alcoholics.a survey was conducted in a population of about 8000 greek high school students (grades 9 and 12) in order to investigate factors possibly contributing to alcohol consumption. a self-rating multiple choice questionnaire was used. the present report focuses on students with alcoholic parents. parameters studied include students' alcohol and drug use, school performance, family relationships, socioeconomic factors and parental control. in 3.3% of the sample parental alcoholism was reported. the re ...20072045240
reduced incidence of bone metastases in irradiated areas after external radiation therapy of prostatic carcinoma.fourteen males, out of 380 patients, treated with radiation to the central pelvis and lumbar spine for poorly differentiated prostatic carcinoma were analyzed in retrospect. the dose of radiation to the bones of the target area was 5,000 cgy. the patients showed no signs of metastases at bone scintigraphy performed in connection with the treatment. in an average of 34 months after finishing radiotherapy, the patients developed metastases at bone scintigraphy. the pattern was similar in all patie ...20072045303
[right-sided endocarditis due to fusobacterium nucleatum].we present 1 case of right sided endocarditis caused by fusobacterium nucleatum in a patient with intravenous drug addiction and human immunodeficiency. the clinical features were fever, anemia, and pulmonary embolism. the echocardiogram showed a giant vegetation originated from the right atrial wall prolapsing in diastole into the right ventricle which disappeared after the patient presented pulmonary embolism. the clinical course was uncontrolled with empiric antimicrobial therapy but it was g ...19912047551
purification and characterization of a 65-kilodalton diisopropylfluorophosphate-binding protein in the outer membrane of fusobacterium nucleatum fev1.a 65-kilodalton protein was identified in the outer membrane of fusobacterium nucleatum fev1 by sds-page. the relative amount of the protein varied during growth, being greatest in stationary phase. the protein was radio-labeled by [125i]-lactoperoxidase treatment of live cells and was only partially extractable with 2% sodium dodecylsulfate (sds) at room temperature, and therefore assumed to be both exposed to the cell surface and peptidoglycan associated. in intact cells the protein bound diis ...19912047749
amoxycillin with clavulanic acid and tetracycline in periodontal therapy.the effects of tetracycline and amoxycillin with clavulanic acid on the clinical parameters and subgingival flora of eight patients with rapidly progressive periodontitis was assessed. subjects received either tetracycline 250 mg four times daily or amoxycillin 250 mg with clavulanic acid 125 mg three times daily for a period of 2 weeks together with subgingival scaling and root planning. both treatment regimens produced significant reductions in bleeding on probing and probing pocket depths whi ...19912050897
synergistic effect on blastogenesis in murine spleen cells of lipopolysaccharide, lipid a, and acid-degraded polysaccharide from fusobacterium nucleatum.interchangeable combinations of fusobacterium nucleatum fev1 lipopolysaccharide (lps) with its split products by acetic acid hydrolysis, i.e. lipid a (la) and degraded polysaccharide (ps), amplified the blastogenic response in murine spleen cell cultures as measured by [3h]thymidine uptake. athymic murine spleen cells precultured with lps-fev1 for 48 h (stage 1), washed twice and cultured together with fresh cells and either la or ps for 72 h (stage 2) gave a synergistic response over that found ...19912059480
amino acid utilization by fusobacterium nucleatum grown in a chemically defined medium.the present investigation evaluated amino acid utilization by 120 strains of fusobacterium nucleatum in a chemically defined medium and attempted to relate the patterns to 3 proposed subspecies of f. nucleatum. strains were inoculated into a chemically defined medium, with and without 2 g/l glucose, consisting of 14 inorganic salts, 21 amino acids, 23 vitamins and cofactors, and 7 purines and pyrimidines. after 7 days of anaerobic incubation, the spent culture medium, as well as the uninoculated ...19902080074
ingestion of bacteroides buccae, bacteroides oris, porphyromonas gingivalis, and fusobacterium nucleatum by human polymorphonuclear leukocytes in vitro.the phagocytic ingestion of clinical isolates and reference strains of bacteroides buccae, bacteroides oris, porphyromonas gingivalis and fusobacterium nucleatum by polymorphonuclear leukocytes (pmns) was studied. special attention was focused on the hydrophobicity of the strains. b. buccae strains, less or equally hydrophobic than pmns, were poorly ingested without opsonization. hydrophobic, but not hydrophilic, strains of b. oris and both hydrophilic and hydrophobic p. gingivalis and f. nuclea ...19902082243
aids literature index. 20072083300
the incidence of periodontopathic microorganisms in young children.thirty-six children in 4 cohorts of 0-1 week, 1-6 months, 1-2 years and 2-2 1/2 years of age were examined for the presence of black-pigmented bacteroides species and some other bacteria suspected of being involved in the subsequent development of periodontal destruction. none of the sought-after bacteria were detected in the first week of life. bacteroides intermedius and bacteroides melaninogenicus were detected as early as 1 month after birth. both of these bacteria were detected in 16-37% of ...19902087345
role of cryptic receptors (cryptitopes) in bacterial adhesion to oral surfaces.progress in characterizing the receptors that promote bacterial attachment to teeth and oral epithelial cells has suggested that hidden molecular segments may frequently be involved. such cryptic receptors, referred to as 'cryptitopes', may become exposed by several mechanisms. hidden segments of salivary acidic proline-rich proteins evidently become exposed when the molecules undergo a conformational change as they adsorb to apatitic mineral. adhesins of actinomyces viscosus and certain other p ...19902088213
clinical and microbial evaluation of treatment regimens to reduce denture stomatitis.this study evaluated the effect of an antimicrobial mouthrinse, denture soft relines, and a placebo rinse on the clinical findings and microbial flora of 78 patients with denture stomatitis. for 28 days the study and control groups performed oral rinses and denture soaks. reline group patients had maxillary denture soft relines that were changed every 7 days. at the end of the study, the mean severity of denture stomatitis was significantly less in the groups that used the study rinse (p less th ...19902088373
[post-traumatic synovitis at the level of the knee]. 20062094111
initial comparison between endoscopic and conventional methods of caries diagnosis.this study was designed to assess the feasibility and practicability of the employment of endoscopic methods for the diagnosis of dental caries and to compare the diagnostic performance, in posterior teeth, of visual endoscopic caries diagnosis (with and without the benefit of differential fluorescence) with that of conventional visual diagnosis, bite-wing radiography, and conventional transillumination. the two endoscopic methods were found to be clinically practicable, to be able to demonstrat ...20022094851
serological investigation of refractory human adult periodontitis.this study examined the difference between the serum antibody profiles in refractory adult periodontitis patients (group a), and compared to those (group b) who responded well to conventional periodontal treatment. the levels of specific igg antibody to actinobacillus actinomycetemcomitans, bacteroides gingivalis, fusibacteriumnucleatum, and eikenella corrodens were assessed in a group of 19 patients (group a) and 11 patients (group b). specific igg serum antibody levels were estimated using bio ...19902096960
distribution and frequency of fusobacterium nucleatum subspecies in the human oral cavity.three reference strains of fusobacterium nucleatum and 32 human oral isolates were compared by a variety of physiological tests, enzyme electrophoretic profiles, sds-page patterns, dna base composition and hybridization to test their possible site specificity and frequency of the recently described subspecies of f. nucleatum. nine of the 11 isolates assigned to f. nucleatum subspecies nucleatum were from diseased sites, whereas isolates from healthy sites were all identified as f. nucleatum subs ...19902098710
sialidase (neuraminidase) activity among gram-negative anaerobic and capnophilic bacteria.a filter paper spot test with 2'-(4-methylumbelliferyl)-alpha-d-n-acetylneuraminic acid as a substrate was used to study the prevalence of sialidase activity among gram-negative anaerobic and capnophilic bacteria. a total of 567 isolates representing four genera of obligate anaerobes and four genera of capnophilic organisms was tested. sialidase activity was detected in 94% of 66 isolates from the bacteroides fragilis group, 98% of 66 b. bivius isolates, and all isolates of the following species ...19902108991
serum antibodies to periodontal bacteria.the purpose of this study was to determine how serum antibodies reactive with periodontitis-associated bacteria with relates to the diagnosis of periodontitis subjects. study groups included localized juvenile periodontitis (ljp) subjects, severe periodontitis (sp) subjects, chronic adult periodontitis (ap) subjects, and age matched controls. twenty-two bacterial strains, representing 18 different species most commonly found in early onset periodontitis were evaluated using serum from ljp, sp, a ...19902117654
studies of the subgingival microflora in patients with acquired immunodeficiency syndrome.two unique forms of periodontal disease, hiv-gingivitis and hiv-periodontitis, have been described in patients with acquired immunodeficiency syndrome (aids). in order to determine the bacterial species associated with periodontitis in aids patients, the predominant cultivable microflora was examined in 21 subgingival plaque samples from 11 aids patients with periodontitis. the presence of putative periodontal pathogens including actinobacillus actinomycetemcomitans, bacteroides intermedius, por ...19902123926
monoclonal antibody-coated latex agglutination assay for identification of actinobacillus actinomycetemcomitans.three monoclonal antibodies (mabs) to lipopolysaccharide of actinobacillus actinomycetemcomitans strain y4 (serotype b) and eight mabs to a serotype b-specific polysaccharide antigen of strain y4 were obtained. latex particles sensitized with an mab to the y4 lipopolysaccharide produced a positive agglutination with whole cells of all three serotypes of a. actinomycetemcomitans, but not with haemophilus aphrophilus, haemophilus paraphrophilus, haemophilus influenzae, porphyromonas (bacteroides) ...19902124492
a rapid diagnosis of anaerobic infection in the oro-maxillary region by gas-liquid chromatography.the relationship between volatile fatty acids (vfas) in pus and infecting bacterial species was examined in order to establish a rapid identification system for anaerobic microorganisms in purulent inflammation in the oro-maxillary region. vfas were detected by the direct injection of pus into gas-liquid chromatography (glc). bacterial examination was carried out by anaerobic culture using blood agar plates. the bacterial identification was carried out mainly according to the vpi manual. analysi ...19902131168
binding specificity of fusobacterium nucleatum to human erythrocytes, polymorphonuclear leukocytes, fibroblasts, and hela cells.eighteen strains of fusobacterium nucleatum were studied with respect to their adherence to human erythrocytes, polymorphonuclear leukocytes, fibroblasts, and hela cells. four types of adherence were found: 1) sugar-sensitive adherence 2) amino acid-sensitive adherence 3) unknown adherence 4) weak adherence. there was no obvious correlation between the patterns of hemagglutination and adherence to other cells. the results indicate not only a complex network of bacterial receptors on human cells, ...19902141873
pharmacokinetics of sufentanil in the elderly surgical patient.the effect of age on the distribution and elimination of sufentanil was studied in seven elderly (77 +/- 5 yr, mean +/- sd) and seven younger (41 +/- 15 yr) neurosurgical patients. following a single iv bolus of sufentanil 2 multiple arterial samples were obtained at timed intervals and plasma concentrations of sufentanil were measured by radioimmunoassay. pharmacokinetic variables were calculated from the derived compartmental models. the initial volume of distribution was signi ...20062147593
interaction of fusobacterium nucleatum 191 with human peripheral blood lymphocytes.fusobacterium nucleatum is frequently isolated in high numbers from the subgingival plaque of patients with periodontal diseases. adherence of these bacteria to several host tissues is lectin-like in that it is inhibited by galactose, lactose, and n-acetyl-galactosamine. since f. nucleatum has the capacity to activate human peripheral blood lymphocytes, the purpose of this study was to determine whether f. nucleatum adheres to lymphocytes and, if so, to determine whether lectin-like interactions ...19902148949
a new 12-lead pediatric ecg interpretation program. 20082151043
identification and characterization of human endothelial cell membrane binding sites for tissue plasminogen activator and urokinase.cultured human endothelial cells synthesize and secrete two types of plasminogen activator, tissue plasminogen activator (t-pa) and urokinase (u-pa). previous work from this laboratory (hajjar, k.a., hamel, n. m., harpel, p. c., and nachman, r. l. (1987) j. clin. invest. 80, 1712-1719) has demonstrated dose-dependent, saturable, and high affinity binding of t-pa to two sites associated with cultural endothelial cell monolayers. we now report that an isolated plasma membrane-enriched endothelial ...19902154465
characterization of the tet m determinants in urogenital and respiratory bacteria.tetracycline-resistant fusobacterium nucleatum, haemophilus ducreyi, mycoplasma hominis, peptostreptococcus spp., ureaplasma urealyticum, and veillonella parvula had dna sequences which showed homology throughout the length of the tet m transposon, tn916. in contrast, gardnerella vaginalis, commensal neisseria spp., and the 25.2-megadalton plasmid family lacked the complete transposon.19902159259
regulation of human monocyte/macrophage function by extracellular matrix. adherence of monocytes to collagen matrices enhances phagocytosis of opsonized bacteria by activation of complement receptors and enhancement of fc receptor inflammation monocytes emigrate from the peripheral circulation into an extravascular area rich in extracellular matrix proteins. in this milieu, phagocytes ingest and kill invading pathogens. in the present studies, we found that monocytes adhered to type i collagen gels phagocytized 2.5-12-fold more opsonized escherichia coli, staphylococcus aureus, streptococcus pyogenes, and streptococcus pneumoniae than plastic-adherent monocytes. the rate of phagocytosis and the number of bacteria inges ...19902168442
[monitoring control of the visual evoked potentials during the surgical treatment of tumors of the chiasmal-sellar area].visual evoked potentials were recorded in different stages of the operation in 12 patients with tumors of the chiasmal-sellar region. a correlation was noted between the dynamics of the p100 latent period and the changes of visual functions after the operation. intraoperative monitoring of visual evoked potentials makes it possible to appraise the functional condition of the optic nerves objectively and correct the techniques and tactics of the operative intervention.20072168648
detection of bovine viral diarrhea virus in serum from cattle by dot blot hybridization assay.a dot blot hybridization assay was developed for use as a rapid screening test to detect bovine viral diarrhea virus (bvdv) in serum from infected cattle. a 1.1. kilobase cdna, prepared from the bvdv genome, was molecularly cloned and used in this study. insert cdna was removed from the puc9 plasmid vector by pst-i restriction endonuclease digestion and purified from plasmid dna by agarose electrophoresis and electroelution. the hybridization probe was prepared by nick translation in the presenc ...19902175527
[characteristics of sensory regulation of the activities in hypochondriacal conditions of different etiologies].the author analyzes the results of an experimental study into sense regulation of the activity of patients with the hypochondriac syndrome. three groups of patients were examined: with neurosis, slow-progressive schizophrenia, and myocardial infarction. four types of self-regulation were distinguished: related to the attitude towards the world, to oneself, to other people, to the characteristic features of the mediation of the relations indicated. it has been discovered that the egocentric tende ...20072176048
transferable tet m in fusobacterium nucleatum.two tetracycline-resistant fusobacterium nucleatum strains were able to transfer, by conjugation, tetracycline resistance and the tet m determinant to recipient f. nucleatum, peptostreptococcus anaerobius, and enterococcus faecalis strains at a frequency of 10(-1) to 10(-8).19902178339
renin is sorted to the regulated secretory pathway in transfected pc12 cells by a mechanism which does not require expression of the pro-peptide.the rat pheochromocytoma cell line pc12 targets secretory proteins into two distinct pathways. when dna encoding human prorenin was transfected into pc12 cells, the protein was sorted into the regulated secretory pathway and released with similar kinetics to noradrenaline upon carbachol stimulation. to determine whether information for targeting prorenin lies within the pro-peptide we have transfected pc12 cells with a construct lacking the pro-peptide coding sequence. the transformed line secre ...19902194793
closed chest cardiac massage. 19962200368
susceptibility of oral bacteria to phenoxyethanol and phenoxyethanol/chlorhexidine combinations.a total of 57 bacterial strains (26 different species) which may be isolated from subgingival plaque were tested for their in vitro susceptibility to phenoxycthanol, a commonly-used antiseptic and preservative. ninety-five percent of the strains, including those associated with chronic inflammatory periodontal disease, were susceptible to concentrations of phenoxyethanol used topically (2% w/v). phenoxyethanol at a concentration of 1% (w/v) was also found that to have a rapid bactericidal effect ...19902202809
the rna polymerases of porphyromonas gingivalis and fusobacterium nucleatum are unrelated to the rna polymerase of escherichia coli.western blot analysis that used antisera to the e. coli core enzyme and sigma factors was used for examination of the rna polymerase of actinobacillus actinomycetemcomitans, streptococcus mutans, fusobacterium nucleatum, and porphyromonas gingivalis. both antisera reacted with proteins in a. actinomycetemcomitans and s. mutans whole-cell extracts. reactions were seen with some f. nucleatum proteins when the anti-core rna polymerase antisera were used, but the cross-reacting proteins were not of ...19902204641
cloning of wild-type pseudomonas solanacearum phca, a gene that when mutated alters expression of multiple traits that contribute to virulence.pseudomonas solanacearum undergoes a spontaneous mutation that pleiotropically reduces extracellular polysaccharide (eps) production, endoglucanase activity, and virulence and increases motility. we refer to the process that coordinately affects these traits as phenotype conversion (pc) and the resulting mutants as pc types. previous research with the wild-type strain aw1 suggested that inactivation of a single locus could mimic phenotype conversion (t. p. denny, f. w. makini, and s. m. brumbley ...19902211505
regulation of fructose metabolism and polymer synthesis by fusobacterium nucleatum atcc for the anaerobic growth of fusobacterium nucleatum atcc 10953 can be derived from the fermentation of sugar (fructose) or amino acid (glutamate). during growth on fructose, the cells formed large intracellular granules which after extraction yielded glucose by either acid or enzymatic hydrolysis. the endogenous polymer was subsequently metabolized, and after overnight incubation of the cells in buffer, the glucan granules were no longer detectable by electron microscopy. anaerobically, w ...19902211506
plaque and chronic inflammatory periodontal disease. a question of ecology.the nature of the relationship between dental plaque and chronic inflammatory periodontal disease (cipd) remains unclear, although there is no doubt that plaque is the direct cause. non-specific, specific and exogenous hypotheses have been proposed to explain plaque-host relationships. current evidence indicates that plaque is part of the natural human microflora, one of many such in nature, and that disruption of oral microbial ecology, due primarily to diet texture changes, leads to gingivitis ...19902212083
recolonization of the subgingival microflora after scaling and root planing in human periodontitis.the purpose of this study was to evaluate the recolonization patterns of the subgingival microflora of adult periodontitis patients after a single session of scaling and root planing. in each of eight patients, three clinically diseased sites were investigated microbiologically by darkfield microscopy and cultural analysis. after initial clinical and microbiological parameters were determined, each subject received a single session of scaling and root planing but no oral hygiene instructions. cl ...19902213468
glucose homeostasis in the rat after liver transplantation. 19902219327
mast cells in the murine oral mucosa are of the connective tissue-type.the distribution, histochemistry, and functional properties of oral (cheeks, soft palate, and tongue) mast cells (mc) was compared to those of peritoneal, cutaneous, and intestinal mc. the ultrastructure of oral mc was also studied. fresh tissue and peritoneal cells were fixed either in absolute ethanol or in periodate lysine 2% paraformaldehyde and embedded in paraffin. for electron microscopy, specimens were fixed in 1% glutaraldehyde in formol and embedded in epon. serial paraffin sections we ...20072223556
mast cells in the murine oral mucosa are of the connective tissue-type.the distribution, histochemistry, and functional properties of oral (cheeks, soft palate, and tongue) mast cells (mc) was compared to those of peritoneal, cutaneous, and intestinal mc. the ultrastructure of oral mc was also studied. fresh tissue and peritoneal cells were fixed either in absolute ethanol or in periodate lysine 2% paraformaldehyde and embedded in paraffin. for electron microscopy, specimens were fixed in 1% glutaraldehyde in formol and embedded in epon. serial paraffin sections we ...20072223556
epidemiological surveillance. development of an international sentinel network of general practitioners (eurosentinel). 20072223567
epidemiological surveillance. development of an international sentinel network of general practitioners (eurosentinel). 20072223567
radioimmunotargeting of human tumour cells in immunocompetent animals.a tumour model system is reported that for many purposes may be an alternative to xenografted nude mice. the model allows immunotargeting of human tumour cells in immunocompetent animals. the target cells are contained in i.p. diffusion chambers (dc) with micropore membrane walls that are permeable to molecules, including the cell specific monoclonal antibodies (moab), but impermeable to cells. thus, the tumour cells are protected from the host immunocompetent cells. in the work here presented t ...19902223574
radioimmunotargeting of human tumour cells in immunocompetent animals.a tumour model system is reported that for many purposes may be an alternative to xenografted nude mice. the model allows immunotargeting of human tumour cells in immunocompetent animals. the target cells are contained in i.p. diffusion chambers (dc) with micropore membrane walls that are permeable to molecules, including the cell specific monoclonal antibodies (moab), but impermeable to cells. thus, the tumour cells are protected from the host immunocompetent cells. in the work here presented t ...19902223574
proposal of three subspecies of fusobacterium nucleatum knorr 1922: fusobacterium nucleatum subsp. nucleatum subsp. nov., comb. nov.; fusobacterium nucleatum subsp. polymorphum subsp. nov., nom. rev., comb. nov.; and fusobacterium nucleatum subsp. vincentii subsp. nov., nom. rev., comb. nov.heterogeneity among isolates of fusobacterium nucleatum has been recognized for many years. the phenotypic properties of 340 strains considered to be f. nucleatum were examined. while these strains were phenotypically similar and fit the description of f. nucleatum, they could be differentiated into three groups on the basis of electrophoretic patterns of whole-cell proteins and dna homology. strains in groups i and ii showed greater than 80% dna homology within groups and less than 75% similari ...19902223601
insulin secretagogues induce ca(2+)-like changes in cytoplasmic mg2+ in pancreatic beta-cells.the effects of insulin secretagogues on the cytoplasmic mg2+ concentration ([mg2+]i) of pancreatic beta-cells were studied in suspensions and in individual beta-cells using dual-wavelength fluorometry and the indicator mag-fura-2. average [mg2+]i was in the 800-900 microm range in a medium containing 3 mm glucose. when the sugar concentration was raised to 20 mm, the cells reacted with an initial lowering of [mg2+]i followed by an increase. the sugar apparently also stimulated leakage of the mg2 ...20072223873
insulin secretagogues induce ca(2+)-like changes in cytoplasmic mg2+ in pancreatic beta-cells.the effects of insulin secretagogues on the cytoplasmic mg2+ concentration ([mg2+]i) of pancreatic beta-cells were studied in suspensions and in individual beta-cells using dual-wavelength fluorometry and the indicator mag-fura-2. average [mg2+]i was in the 800-900 microm range in a medium containing 3 mm glucose. when the sugar concentration was raised to 20 mm, the cells reacted with an initial lowering of [mg2+]i followed by an increase. the sugar apparently also stimulated leakage of the mg2 ...20072223873
cognitive and affective disorders in elderly non-insulin-dependent diabetes mellitus, performance of complex cognitive tasks requiring the storage and retrieval of new information is poorer than in age-matched controls. by contrast, performance of less demanding tasks such as immediate memory and simple reaction time is essentially equivalent for niddm patients and controls. this pattern parallels the cognitive change observed with normal aging, in which age differences are minimal on less demanding immediate memory tasks but older adul ...20072224744
cognitive and affective disorders in elderly non-insulin-dependent diabetes mellitus, performance of complex cognitive tasks requiring the storage and retrieval of new information is poorer than in age-matched controls. by contrast, performance of less demanding tasks such as immediate memory and simple reaction time is essentially equivalent for niddm patients and controls. this pattern parallels the cognitive change observed with normal aging, in which age differences are minimal on less demanding immediate memory tasks but older adul ...20072224744
stimulation of serotonin2 receptors in the ventrolateral medulla of the cat results in nonuniform increases in sympathetic outflow.topical application of the serotonin2 agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane or doi, in a dose of 30 micrograms/side to the intermediate area of the ventrolateral surface of the medulla produced a significant increase in mean arterial pressure with no significant change in heart rate both in intact animals (n = 8) and in cervically vagotomized animals (n = 3). the pressor response of doi was blocked by pretreatment of the intermediate area with ketanserin, a serotonin2 antagonist ...19902225358
on the treatment of enchondroma.we recommend simply removing an enchondroma without filling the cavity with cancellous bone or plaster-of-paris. this method can also be applied to other benign bone conditions, such as aseptic necrosis.20072230499
trade and generic names of drugs. 20072234623
[effect of enalapril on heart rate, arterial blood pressure and exocrine pancreatic secretion in the alert dog].a changed exocrine pancreatic secretion could be a pathogenetic factor of an acute pancreatitis after administration of angiotensin-converting enzyme (ace) inhibitors. in six conscious dogs with gastric and duodenal thomas fistulas we studied the effect of an intravenous (iv.) bolus injection of 10 mg enalaprilat, an intraduodenal (id.) bolus injection of 20 and 40 mg enalapril (e.), and 0.15 m nacl (20 ml iv., resp., id.) on pancreatic bicarbonate- and protein output in response to secretin (20 ...19902238764
two cytochrome p-450 isoforms catalysing o-de-ethylation of ethoxycoumarin and ethoxyresorufin in higher plants.the o-dealkylating activities of 7-ethoxycoumarin o-de-ethylase (ecod) and 7-ethoxyresorufin o-de-ethylase (erod) have been fluorimetrically detected in microsomes prepared from manganese-induced jerusalem artichoke tubers. cytochrome p-450 dependence of the reactions was demonstrated by light-reversed co inhibition, nadph-dependence, nadh-nadph synergism and by use of specific inhibitors: antibodies to nadph-cytochrome p-450 reductase, mechanism-based inactivators and tetcyclasis. apparent km v ...20082241905
cocaine-induced stroke: first jamaican case. 20072243239
the biotin-dependent sodium ion pump glutaconyl-coa decarboxylase from fusobacterium nucleatum (subsp. nucleatum). comparison with the glutaconyl-coa decarboxylases from gram-positive bacteria.membrane preparations of fusobacterium nucleatum grown on glutamate contain glutaconyl-coa decarboxylase at a high specific activity (13.8 nkat/mg protein). the enzyme was solubilized with 2% triton x-100 in 0.5 m nacl and purified 63-fold to a specific activity of 870 nkat/mg by affinity chromatography on monomeric avidin-sepharose. the activity of the decarboxylase was strictly dependent on na+ (km = 3 mm) and was stimulated up to 3-fold by phospholipids. the glutaconyl-coa decarboxylases from ...19902244788
acute guillain-barré syndrome. 19892249465
[bcl-2 gene involved in t(14;18) translocation]. 19902255071
specific amplification of rearranged immunoglobulin variable region genes from mouse hybridoma this article we show how the polymerase chain reaction (pcr) and primers designed for conserved sequences of leader (l), framework one (fr1) and constant (const) regions of immunoglobulin light and heavy chain genes can be used for the cloning and sequencing of rearranged antibody variable regions from mouse hybridoma cells. rna was extracted from the mouse hybridoma cells secreting mabs: ior-t3a (anti-cd3), c6 (anti-p1 of n. meningitidis b385), ior-t1 (anti-cd6), cb-cea.1 (anti-carcinoembryo ...19902258182
[foreign bodies of the digestive tract]. 20082259119
[foreign bodies of the digestive tract]. 20082259119
[neuro-emotional stress of work at a factory]. 20082262147
lysocardiolipin formation and reacylation in isolated rat liver mitochondria.liver mitochondrial cardiolipin (cl) is distinguished from other phospholipids by the presence of linoleoyl in almost all molecular species, and the biosynthesis of these species is not yet understood. the present study was carried out in order to test the hypothesis that the linoleoyl proportion of cl may be specifically enriched by a deacylation-reacylation cycle. incorporation of [14c]glycerol 3-phosphate into the metabolites of the cl pathway was accompanied by formation of 14c-labelled mono ...19902268287
coaggregation of oral candida isolates with bacteria from bone marrow transplant vitro coaggregation between candida species isolated from immunosuppressed bone marrow transplant recipients and oral bacteria was investigated. each candida strain showed a different pattern of coaggregation with the 22 bacterial strains studied. two strains of lactobacillus amylovorus isolated from separate bone marrow transplant patients and fusobacterium nucleatum (vpi 10197) coaggregated with all candida strains. ten bacterial strains showed no coaggregation with the candida strains. a v ...19902279992
associations between six dna probe-detected periodontal bacteria and alveolar bone loss and other clinical signs of periodontitis.the purpose of the present study was to assess the associations between the presence and amounts of actinobacillus actinomycetemcomitans, bacteroides gingivalis, b. intermedius, eikenella corrodens, wolinella recta, and fusobacterium nucleatum in the periodontal pocket and the degree of alveolar bone loss and other clinical signs of periodonitis, such as probing pocket depth, attachment level, and presence of bleeding on probing at the same site. the study material comprised 16 subjects with or ...19902288212
increased formation of dna adducts in cultured fibroblasts of patients with aplastic anemia after in vitro incubation with benzo(a) inbred mice strain dba/2, genetically controlled differences in aryl hydrocarbon hydroxylase (ahh) activity have been demonstrated that predispose to aplastic anemia. to test the hypothesis of a similar mechanism in humans, we studied the formation of benzo(a)pyrene dna adducts and water-soluble metabolites in skin fibroblasts from eight patients with aplastic anemia and eight normal controls. the ratio of water-soluble metabolites and dna adducts was 46.5 +/- 16.6 in patients and was signifi ...20082289825
design, properties, and effective use of the oral chelator l1 and other alpha-ketohydroxypyridines in the treatment of transfusional iron overload in thalassemia. 20082291562
current therapy of ischaemic stroke. 20082292554
grading white matter lesions on ct and mri: a simple scale.we developed and tested a simple three-point scale for grading white matter lesions in anterior and posterior regions of the brain. twenty four ct scans and 24 mri scans were separately judged by 11 and five observers, respectively, on the presence and severity of white matter lesions. the observers were radiologists and neurologists. for ct scans, these periventricular changes were graded according to their extent as absent, or partly involving the white matter, or extending up to the subcortic ...20082292703
determination of retinol, alpha-tocopherol, and beta-carotene in serum by liquid chromatography. 20082292933
microbial patterns in pooled subgingival plaque samples from young adults with advanced marginal periodontitis.different bacterial profiles of subgingival plaque have been described for different clinical categories of marginal periodontitis. in the present investigation the subgingival microflora was studied in young adults with advanced marginal periodontitis. from 12 patients pooled subgingival plaque samples from 5 advanced stages of diseased sites were examined by direct differential phase-contrast microscopy and by cultivation on enriched and selective media. the proportions of the following genera ...19902293348
capnophilic and anaerobic bacteremia in neutropenic patients: an oral source.the currently accepted empiric antibiotic therapy for bacterial infections in neutropenic patients may not cover the possibility of capnophilic and anaerobic bacteremia. many of these infections develop in patients with severe mucositis or periodontitis, and the type of organisms recovered also suggests an oral source of infection. we present two cases of bacteremia in neutropenic patients who had been empirically treated with ceftazidime and piperacillin plus amikacin. in the first case a beta- ...19902305182
species-specific oligodeoxynucleotide probes for the identification of periodontal bacteria.oligodeoxynucleotide probes were developed for identification of the periodontal bacteria actinobacillus actinomycetemcomitans, bacteroides gingivalis, b. intermedius types i and ii, b. forsythus, eikenella corrodens, fusobacterium nucleatum, haemophilus aphrophilus, streptococcus intermedius, and wolinella recta. probes were designed by sequencing the 16s rrna for each bacterium, identifying hypervariable regions, and chemically synthesizing species-specific probes. these probes were specific w ...19902312676
growth stimulation of treponema denticola by periodontal microorganisms.previous experiments have indicated that enrichment of subgingival plaque in human serum can lead to the accumulation of treponema denticola. t. denticola depends on bacterial interactions for its growth in serum. aim of the present study was to identify specific microorganisms involved in the growth stimulation of t. denticola. to this end, strains isolated from previous plaque enrichment cultures were tested for growth stimulation in co-cultures with t. denticola. in addition, growth of t. den ...19902321929
diisopropylfluorophosphate-binding proteins in the outer membrane of fusobacterium nucleatum: strain variations.six strains of fusobacterium nucleatum were tested for their ability to react with [3h]diisopropylfluorophosphate (dfp), a serine protease inhibitor. several cytoplasmic proteins were labelled but the strongest labelling was regularly observed in a few outer membrane proteins. the number and the molecular mass of the proteins detected varied according to the strain tested. a 61 kda protein was labelled in all strains tested, including the two type strains atcc 10953 and atcc 25586. a 65 kda prot ...19902323539
long-term clearance of inhaled uo2 particles from the pulmonary region of the rat.this paper reports on an enriched uranium dioxide (uo2) mass clearance study undertaken with fischer-344 rats. the uo2 had a uranium (u) isotopic composition of 0.79% 234u, 92.8% 235u, 0.34% 236u and 6.06% 238u, by mass, with an alpha-particle activity of 1.91 bq micrograms-1. forty-six rats were exposed to an enriched uo2 aerosol that had an activity median particle aerodynamic diameter ranging from 2.7 to 3.2 microns. the rats were killed from 1 to 720 d post-inhalation (pi). the mass of enric ...19902323929
phytochrome from the green alga mesotaenium caldariorum. purification and preliminary characterization.a method to purify the phytochrome photoreceptor from the unicellular green alga mesotaenium caldariorum is presented. preparative scale formation of algal protoplasts and controlled osmotic cell lysis have permitted separation of intact organelles from the phytochrome-enriched soluble protein fraction. we have utilized the observation that red light-absorbing (pr) and far-red light-absorbing (pfr) forms of phytochrome are differentially retained on an anion exchange matrix to purify m. caldario ...20082324111
susceptibility and resistance of plaque bacteria to minocycline.the in vitro susceptibility of 55 strains of subgingival plaque bacteria to minocycline was determined. a concentration of 1 microgram/ml minocycline was found to inhibit 85% of the strains tested and the mic ranged from 0.03 to 32 micrograms/ml. for 71% of the strains tested the mbc was at least 4 times greater than the corresponding mic, suggesting a bacteriostatic activity for minocycline. a concentration of 20 mg/ml of magnesium ions was capable of neutralizing 8 micrograms/ml of minocycline ...19902324922
[intraosseous administration of thymalin in the combined treatment of children with acute odontogenic osteomyelitis].experience gained in the treatment of 63 children has demonstrated the validity of bone perforation and intraosteal drug lavage in a complex of therapeutic measures for acute mandibular odontogenic osteomyelitis running an unfavorable course. incorporation of immunostimulant thymalin in the solutions used for intraosteal lavage of the inflammation focus in this condition is conducive to normalization of the cellular and humoral immunity and liquidation of the pathologic process without destructi ...19992326818
genetic basis of tetracycline resistance in urogenital bacteria.the distributions of the nucleotide sequences related to the tetracycline resistance determinants tet k, tet l, tet m, and tet o were studied by dot blot hybridization with randomly chosen clinical urogenital tract isolates of viridans group streptococci, streptococcus agalactiae, enterococcus faecalis, gardnerella vaginalis, lactobacillus spp., fusobacterium nucleatum, peptostreptococcus spp., and veillonella parvula. among the peptostreptococcus spp., 79% of the isolates hybridized with one (6 ...19902327774
any value for desmopressin acetate (ddavp) in cardiopulmonary bypass operation? 20082329836
screening adolescents for depression and parent-teenager conflict in an ambulatory medical setting: a preliminary investigation.because more than 60% of adolescent visits to physicians last less than 10 minutes, simple screening devices to identify persons at risk for social morbidity are needed. the result of a pilot screening instrument for depression and parent-teenager conflict is described. a seven-item questionnaire (three items for depression and four items for parent-teenager conflict), the beck depression inventory (bdi), and the conflict behavior questionnaire (cbq), were administered to 226 adolescents at a hi ...20082330245
inhibitory effects of neuropeptide y on adenylate cyclase of rabbit ciliary processes.the inhibitory effect of neuropeptide y (npy) was studied on the adenylate cyclase (ac) activity in homogenates of rabbit ciliary processes and compared with that of the alpha 2-adrenergic agonist clonidine (cln). npy inhibited basal ac activity as well as ac activity stimulated by isoproterenol (iso), vasoactive intestinal polypeptide (vip) or forskolin (fsk). the extent of this inhibition corresponded well to the inhibition elicited by cln. the inhibitory effects of npy and cln appeared to be ...19902335109
multiple periodontal abscesses after systemic antibiotic therapy.multiple periodontal abscesses were reported in medically compromised patients. we examined patients with a non-contributory medical history referred for the treatment of numerous periodontal abscesses. all patients had taken oral broad spectrum antibiotics 1 to 3 weeks prior to the outburst of the abscesses (8 patients: penicillin, 2 patients: tetracycline). the patients suffered from advanced periodontal disease, 82% of the examined sites showed probing depths greater than 3 mm, 56% attachment ...19902347952
growth conditions and outer membrane proteins of fusobacterium nucleatum.fusobacterium nucleatum strains atcc 10953, atcc 25586, f1 f3, f6, and fev1 were grown in different media. the influence of growth conditions on the outer membrane proteins (omps) was analyzed by sodium dodecyl sulfate--polyacrylamide gel electrophoresis (sds-page). there were no apparent differences in the outer membrane protein profiles when cells in the same phase of growth in various rich media were compared. differences, however, were observed between early logarithmic phase and stationary ...19902349450
neurocristopathy syndrome: review of four cases.aberrant embryologic development of the neural crest may clinically result in one of several patterns of malformation. four examples of the neurocristopathy syndrome are described that collectively feature a very broad range of expression in these infants. because of the many expressions, the syndrome may not be recognized. we believe that greater familiarity with the disorder will aid in the discovery of unsuspected anomalies and provide clues about predisposing etiologies.20082359735
falls and hip fracture in hong kong chinese.the risk factors for hip fracture were studied in four hundred patients and eight hundred community and hospital controls. falling was found to be important as a direct cause of fracture. a history of falls was a significant risk factor for hip fracture in men and women younger than 70, but was less important in older men and women. medical conditions and treatments did not occur more frequently in hip fracture patients with a history of falls than in patients without, and the patients with a hi ...20082359827
blastogenesis and polyclonal immunoglobulin synthesis in murine spleen cells stimulated with lipopolysaccharide, lipid a and acid-degraded polysaccharide from fusobacterium nucleatum.lipopolysaccharide of fusobacterium nucleatum strain fevl was split by acid hydrolysis. the split products, i.e. lipid a and degraded polysaccharide were mitogenic for murine spleen cells as measured by uptake of [3h]thymidine. the uptake of [3h]thymidine was dose-dependent. incubation of spleen cells with stimulants for 3 days resulted in a polyclonal activation of immunoglobulin synthesis. higher mitogenic response and immunoglobulin production were found in spleen cells of athymic mice compar ...19902369526
[radical surgical intervention with conventional radiation versus multimodality therapy protocol in undifferentiated thyroid cancer].out of a total of 550 patients with thyroid cancer diagnosed over the 16-year period 1972-june 1989, 44 showed undifferentiated carcinoma and were treated by thyreoidectomy and early postoperative external irradiation. in order to analyse the outcome in patients treated by primary surgery in contrast to patients treated by means of a multimodal therapy concept we compared our surgical procedures with regard to primary surgical approach, early postoperative course, operative complications and sur ...20082375117
they need more exercise. 20062376809
is honesty the best policy? 20072391008
preliminary studies on melatonin in the treatment of myelodysplastic syndromes following cancer chemotherapy.experimental studies have suggested that the pineal hormone melatonin, in addition to its documented antineoplastic action, plays a role in the physiological regulation of blood cell proliferation. based on these data, we evaluated the clinical effects of melatonin therapy in patients with myelodysplastic syndrome (mds) secondary to cancer chemotherapy for primary neoplasms. the study was carried out on six patients, and melatonin was given orally at a dose of 20 mg/daily, following a schedule p ...20082395074
risk factors for kaposi's sarcoma in the vancouver lymphadenopathy-aids our ongoing cohort study of homosexual men, the ratio of new kaposi's sarcoma (ks) cases to new opportunistic infections (oi) during the periods 1982-1985, 1986-1987, and 1988-1989 fell from 0.75 (9 ks: 12 oi) to 0.57 (12 ks:21 oi) to 0.27 (4 ks:15 oi), respectively. to examine factors associated with the development of ks as compared to oi, we compared antecedent risk factors in 25 ks cases and 48 oi "controls." in univariate analyses, several classical hiv risk factors including numbers of ...19902395081
health care in the united states. our dynamic jigsaw puzzle. 20082405797
resistance to beta-lactam antibiotics in anaerobic bacteria.the known mechanisms of beta-lactam resistance in anaerobic bacteria involve production of beta-lactamases, alteration of penicillin-binding proteins, and blocked penetration of beta-lactam antibiotics through bacterial outer membranes. the most important factor in beta-lactam resistance is production of beta-lactamases, which have been found in various bacteroides, fusobacterium, and clostridium species. beta-lactam resistance in bacteroides fragilis is commonly mediated by beta-lactamases that ...19902406875
modulation of hla-dr antigens in the gingival epithelium in vitro by heat-killed fusobacterium nucleatum and e. coli lipopolysaccharide.the in vitro influence of the periodontopathic organism fusobacterium nucleatum (fn) on gingival tissue was examined using an organ culture system. treatment of gingival explants obtained from periodontally diseased sites with suspensions of fn, stimulated the expression of hla-dr antigens by langerhans cells (lc) in a dose-dependent fashion, and produced a maintenance of the lc markers t6 and atpase. similar effects were seen when e. coli lipopolysaccharide (lps) was substituted for suspensions ...19852414424
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