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second reading for experiments bill. 2005538875
[sisomicin dosage in renal failure]. 2005538909
comparison of the metabolism of 2,4-toluenediamine in rats and mice.the excretion, distribution, and metabolism of 2,4-toluenediamine (tda) have been compared in rats and mice. the elimination of tda metabolites into urine was faster and more complete in mice than in rats. however, the feces of rats accounted for a greater percentage of the dose in rats than in mice. the distribution of metabolites in tissues were considerably lower in mice than in rats. the major urinary metabolites observed in the rat were 4-acetylamino-2-aminotoluene, 2,4-diacetylaminotoluene ...1979547012
[living or dead language - contribution to its understanding in analysis in an institution. study of a clinical case]. 2005547298
[further research on the differentiation in vitro of chick-embryo skin in the presence of histones].in the present study the authors have carried out further researches on the differentiation of six day limb skin from chick embryo cultured "in vitro" in a complete medium supplemented with histones. when histones were added to the medium in the first two days "in vitro", epidermal keratinization was not observed. however the addition of histones after four days "in vitro" did not interfere with epidermal differentiation.2005548050
morphometric analysis of the loss of chief and parietal cells after partial gastrectomy for duodenal ulcer.relative chief and parietal cell volume densities were estimated morphometrically in the remnant mucosa of 98 male patients ("series"), operated on for duodenal ulcer by the billroth ii, and in the body mucosa of 55 subjects, age and sex matched, from a random series of a finnish population ("controls"). the relative volumes of chief and parietal cells were significantly lower in the series than in the controls. the mean chief cell: parietal cell ratio was significantly higher in the series than ...2005549432
sexuality and head and neck cancer. 1980551009
[the continuing education for specialist in internal medicine in the district of karl marx stadt]. 2005551566
rate of alcoholism diagnoses in community mental health centers: the effect of the presence of an alcoholism treatment program.in this study, it was hypothesized that community mental health centers (cmhcs) with distinct alcoholism treatment programs (atps) would diagnose alcohol problems at a greater frequency than would centers without atps. it was also hypothesized that psychoses, personality disorders, and transient situational disturbances would be diagnosed more frequently in cmhcs without atps. yearly diagnostic admission data from nine of nebraska's cmhcs (four with atps, five without) were used. it was found th ...2005552314
["feature cards": a simple and logical system for clinical research]. 2005554113
lethality for mice and chick embryos, pyrogenicity in rabbits and ability to gelate lysate from amoebocytes of limulus polyphemus by lipopolysaccharides from bacteroides, fusobacterium and veillonella.phenol-water extracted lipopolysaccharides (lps) from veillonella, fusobacterium nucleatum, bacteroides fragilis and bacteroides melaninogenicus were lethal for mice and 11-days-old chick embryos, pyrogenic in rabbits, and gelated limulus amoebocyte lysate. mouse lethality was considerably enhanced by actinomycin-d. in all test systems the endotoxin activity of veillonella and fusocbacterium lps was comparable to that of lps from salmonella enteritidis, which was included as a reference endotoxi ...1977564596
susceptibility to erythromycin of anaerobes of the genera bacteroides, fusobacterium, sphaerophorus, veillonella, clostridium, corynebacterium, peptococcus, peptostreptococcus.the minimal inhibitory concentrations (mic) of erythromycin were determined by broth dilution tests for 313 anaerobic strains, most of which were clinical isolates. all the gram-positive anaerobes tested (84 peptococcaceae, including 21 peptostreptococcus anaerobius and 15 peptococcus variabilis; 65 corynebacterium acnes and 29 clostridium strains, including 13 c. perfringens) were sensitive (mic values 0.012 through 3.12 microgram erythromycin/ml); so were 111 cultures of gram-negative anaerobe ...1977580038
compact liquid nitrogen storage system yielding high recoveries of gram-negative anaerobes.a simple and compact system suitable for the preservation of fragile gram negative anaerobes and other bacteria in liquid n2 has been developed. polypropylene straws used as specimen containers can be used easily within glove bags of anaerobic chambers, and their small size greatly increases the number of cultures which can be stored. ancillary equipment and methods developed are described. the overall system was tested, using streptococcus mutans, fusobacterium nucleatum, and selenomonas sputig ...1978623475
immunoelectron microscopic localization of lipopolysaccharides in the cell wall of bacteroides oralis and fusobacterium nucleatum.lipopolysaccharides (lps) have been extracted and purified from two anaerobic gram-negative bacteria: bacteroides oralis and tfusobacterium nucleatum. chemical analysis of the preparations showed a great proportion of neutral sugars, mainly glucose, in lps of b. oralis. in rabbits, lps of b. oralis induced both immunoglobulin m and g antibodies in contrast to lps of f. nucleatum, to which only immunoglobulin m antibodies were produced. an immunohistochemical method with horseradish peroxidase-la ...1978624589
[lung abscess due to fusobacterium nucleatum (author's transl)].a patient with epilepsy, 45 years of age, developed a lung abscess due to fusobacterium nucleatum which was successfully treated with intravenous lincomycin. quantitative anaerobic cultures of washed sputum proved to be useful in detecting the causative organism.1978650887
chemotypes of fusobacterium nucleatum lipopolysaccharides.lipopolysaccharides (lps) were isolated from 20 strains of fusobacterium nucleatum and examined by paper chromatography, gas liquid chromatography and colorimetric methods for the presence of neutral sugars, amino sugars and 2-keto-3-dexoxy-octonate (kdo). the lps had in common glucosamine, l-glycero-d-manno-heptose, glucose and kdo. the kdo content was low. galatose, rhamnose and d-glycero-d-manno-heptose were found in some strains. based on the sugar composition of the lps, the f. nucleatum st ...1978665242
in vitro activity of tiamulin (81.723 hfu), a new pleuromulin derivative, against clinically significant anaerobes.the susceptibility of more than 40 strains of gram-negative and gram-positive anaerobes to tiamulin (sandoz 81.723 hfu), a new pleuromulin (pleuromutilin) derivative, was determined by broth dilution and agar dilution tests. the influences of density of the inoculum upon mics was studied by a specially designed pour plate-technique. bacteroides fragilis, b. vulgatus, b. splanchnicus, b. oralis, b. asaccharolyticus, b. melaninogenicus, fusobacterium fusiforme (f. nucleatum), sphaerophorus necroph ...1978690009
a modified plate holding system for anaerobic cultures.a modified plate holding system for anaerobes has been developed which: 1) effectively reduces the volume of oxygen-free gas required, 2) promotes earlier bacterial growth, and 3) monitors the anaerobic atmosphere of the holding vessel and the rate of gas flow. cultures of bacteroides fragilis, clostridium perfringens, c. septicum, fusobacterium nucleatum, peptococcus sp. and propionibacterium sp. were evaluated for optimal growth. all cultures grew as well as or better when preincubated in the ...1976782243
effect of sonic treatment on pure cultures and aggregates of bacteria.pure cultures of a variety of bacteria were treated with ultrasonic energy using a sonic probe. fractions of organisms killed at different sonic energies were calculated, and streptococcus mutans was 600 times more resistant than fusobacterium nucleatum, the most sensitive organism tested. the effects of sonic treatment on aggregates of bacteria were examined, and the results were interpreted as a model of the events that probably occur during the sonic dispersion of dental plaque.1976819454
chemical structure of the lipid a component of lipopolysaccharides from fusobacterium nucleatum.the lipid a component of lipopolysaccharides from fusobacterium nucleatum fev 1 consists of beta-1',6-linked d-glucosamine disaccharides, which carry two phosphate groups: one in glycosidic and one in ester linkage. the amino groups of the glucosamine disaccharides are substituted by d-3-hydroxyhexadecanoic acid. the hydroxyl groups of the disaccharide backbone are acylated by tetradecanoic, hexadecanoic, and d-3-hydroxytetradecanoic acids. part of the ester-bound d-3-hydroxytetradecanoic acid i ...1977830651
[in vitro susceptibility of bacteroidaceae to cefoxitin and cephalothin (author's transl)].the activity of the new cephamycin c derivatives cefoxitin against 102 clinical isolates of bacteroidaceae (95 bacteroides strains and 7 fusobacterium-sphaerophorus cultures) was determined by tube dilution and standardized agar diffusion tests and compared to that of cephalothin. cefoxitin was more active than cephalothin against 56 bacteroides fragilis strains, 19 bacteroides thetaiota-omicron strains and two bacteroides splanchnicus strains. the difference seemed less pronounced with five bac ...1977856727
hepatic necrobacillosis. report of a case resembling metastatic tumor.a 47-year-old man had multiple pyogenic liver abscesses from which the anaerobic bacteria fusobacterium nucleatum and peptostreptococcus were isolated. the clinical course, diagnostic evaluation, and appearance of the lesions at surgery suggested metastatic tumor. histologically, the lesions consisted of necrotic liver tissue surrounded by zones of acute and chronic inflammation and fibrous connective tissue closely resembling the lesions of hepatic necrobacillosis attributable to f necrophorum. ...1977869652
those dangerous roentgens and how to control them: ii radiation hazards and protection as they relate to exposures in dental radiography. 20051064920
effect of repeated bloodletting on the incidence of 2,7-faa-induced rat leukemia.the oral administration of n,n'-2,7-fuorenylenebisacetamide (2,7-faa) induced leukemia, especially mature granulocytic leukemia, in rats. 2,7-faa was administered to the rats of the wistar strain and a small amount of bloodletting was repeated for a long period. the incidence of leukemia and mature granulocytic leukemia became elevated by bloodletting. the induction of mature granulocytic leukemia might be increased by the promotion of granulopoiesis which had been suppressed by 2,7-faa.19761068628
[the nature of nuclear enlargement in urethane and isoprotenol-stimulated salivary glands (author's transl)]. 19751073694
the aching mouth and the aching psyche. 20051074368
osteogenesis imperfecta congenita and tarda: a temporal bone report.the temporal bone report of an operated case of osteogenesis imperfecta tarda is presented. histological examination confirmed the presence of bilateral fixation of the footplate by otosclerosis as the cause of the conductive hearing loss. fragility of bony septae in the mastoid and of the stapedial crura were observed. sensorineural impairment in later years with a reduction in neural elements in the cochlea appear related to the extent and activity of the otosclerotic foci. additional temporal ...19751079440
[non-invasive diagnosis of occlusive disease of the carotid arteries]. 20051087432
t-lymphocytes and psoriasis. 20051087550
polymorphism of human color vision.the genetic polymorphism of human color vision is examined within the framework of a photopigment replacement model. an analysis of the x-linked recessive dichromacies and anomalous trichromacies indicates that one source of variability of normal color perception may be the inclusion of several distinct phenotypes in what is usually described as normal color vision. this analysis also reveals the cause of the dominance hierarchy at the protan and deutan loci, the perceptual effects of dosage com ...19761087832
the impact of laboratory error on the normal range: a bayesian model.interpretation of clinical laboratory results, aside from clinical considerations, is based on the probability of the result being within a given normal range. this probability is influenced by the degree of error inherent in the analytical method. it would be advantageous to assign a more definite probability to the result of the measurement by combining the error distribution of the result around the true value and the distribution of the healthy population that serves as a reference. bayesian ...20051112041
improved methodology and precision using a straight base line technique for the quantitation of proteins by two dimensional immunoelectrophoresis. 20051112067
pattern and depth discrimination from random dot stereograms.the discrimination of depth and pattern was investigated using random dot stereograms. for all four subjects, the psychometric function for depth judgments (probability of correct response) was clearly superior to pattern judgments over a range of ten crossed or uncrossed binocular disparity values. degrading the visual images, either monocularly or binocularly, with various convex lens power (fogging lenses) reduced both depth and pattern discrimination across all disparity values, rather than ...20051130488
gastrin and insulin release. 20051140520
practical use of electron microscopy for the diagnosis of glomerular disease.in the past few years many clinically significant new glomerular lesions have been reported from observations made on renal biopsy specimens by electron microscopy. the clinical applicability of electron microscopy is illustrated by examples of specific ultrastructural patterns of glomerular reaction making possible a more accurate diagnosis, prognosis, and prediction of the response to treatment.20051150220
antiinflammatory beta-arylamidoacrylic acids.a series of 34 beta-arylamidoacrylic acids was prepared and examined for antiinflammatory activity. these compounds are vinylogous carbamic acids, and several displayed activity equal to phenylbutazone in the rat pleural effusion model. highest activity was associated with structures bearing halogen and cyano substituents. amides were inactive.19751151961
carcinoma of the male breast following thymic irradiation.a white male teenager with carcinoma of the breast had received radiation therapy for an asymptomatic enlarged thymus on the second, fourth and seventh days of life. the dose delivered to the infant breasts, the latent period, and the unusually young age of the patient suggest that the malignancy was related to the course of radiotherapy.20051153746
effects of crude and pure cholera toxin on prostaglandin.investigations were made into the effects of crude and pure preparations of cholera toxin on the release of prostaglandin-like substances (pls) from rabbit ileum. perfusion of ileal loops in vivo with buffer containing crude toxin was followed by a release of pls into the perfusate, in amounts up to 37.5 ng/30 min (pge2 equivalents). in contrast, no detectable pls was released when ileal loops were perfused with pure toxin. similarly, pieces of ileum opened longitudinally released pls in amounts ...19751153796
[proceedings: case of right atrial dilatation]. 20051160122
dietary fats and properties of endoplasmic reticulum: i. dietary lipid induced changes in composition of microsomal membranes in liver and gastroduodenal mucosa of rat.rats were fed for four weeks with different lipid diets to determine the effects on the endoplasmic reticulum membranes of the liver and on the postmitochondrial supernatant fraction of the gastroduodenal mucosa. the diets contained cholesterol, cacao butter, olive oil, and these in combination. the results showed that dietary lipids were able to modify the composition of the hepatic endoplasmic reticulum and, to a lesser extent, that of postmitochondrial fraction of gastroduodenal mucosa. cacao ...19751160521
a pulse fluorometry study of lipoamide dehydrogenase. evidence for non-equivalent fad centers.the time dependence of the fluorescence of tryptophanyl and flavin residues in lipoamide dehydrogenase has been investigated with single-photon decay spectroscopy. when the two fad molecules in the enzyme were directly excited the decay could only be analyzed in a sum of two exponentials with equal amplitudes. this phenomenon was observed at 4 degrees c (tau-1 = 0.8 ns, tau-2 = 4.7 ns) and at 20 degrees c (tau-1 = 0.8 ns, tau-2 = 3.4 ns) irrespective of the emission and excitation wavelengths. t ...19751168573
letter: an easy death. 20051169095
diarrhoeae in thyroid medullary carcinoma: role of prostaglandins and therapeutic effect of nutmeg.in a patient with medullary carcinoma of the thyroid with pulmonary metastases who presented with diarrhoea and steatorrhoea large amounts of prostaglandin-like material were present in peripheral blood, and some was extracted from the tumour. the diarrhoea which persisted after thyroidectomy responded to treatment with nutmeg.20051169097
endogenous prostaglandin release contributes directly to coronary artery tone.an in vitro coronary artery preparation of beef heart was found to synthesize and release continuously large amounts of a prostaglandin of the e type. inhibition of prostaglandin synthesis with aspirin, indomethacin, or eicosa-5,8,11,14-tetraynoic acid induced a sustained contraction of the coronary artery, and pretreatment with indomethacin diminished markedly the output of prostaglandin into the bathing medium. it appears that prostaglandin e1, generated from within the vessel wall itself, may ...19751175084
psychiatric morbidity in a sample of a london coroner's open verdicts.one hundred and thirty-four deaths recorded as open verdicts in the inner west london coroner's district during 1969 and 1970 have been surveyed for evidence of mental illness. for 110 (82 per cent) of these deaths the probable verdicts were suicide or accident and they were reclassified as undetermined deaths. of these deaths 73 per cent were diagnosed as mentally ill, 54 per cent were receiving medical treatment for psychological symptoms before death, 42 per cent had a history of psychiatric ...20051182365
exercise and asthma: overview and clinical impact.the question of the relationship between exercise and asthma dates back to the second century a.d. and was not resolved until r.s. jones and co-authors in 1962 reported that there were in reality two effects on the asthmatic patient from exercise depending on the duration of the exercise. short-term exercise of less than four minutes resulted in bronchodilatation, whereas longer-term exercise resulted in bronchoconstriction. exercise-induced bronchospasm occurs in all ages but is more common in ...20021187272
neurochemical correlates of alloxan diabetes: brain aminotransferase heterogeneity in the rat. 19751196005
what's your diagnosis? 20051196062
a vector model of disease for teaching and diagnosis. 19751196157
phloroglucinol derivatives of eleven dryopteris species from japan. 20051197418
[bronchopneumopathies due to cereals in grain silos workers: etiological and pathogenetical aspects]. 20051226180
the role of the surrounding tissue in the propagation of waves through the arterial system.a theoretical analysis of the flow in arteries is presented, taking into consideration the role played by the surrounding tissues in determining the speed of propagatoion and the damping of the blood pressure pulse. this study was undertaken (a) to exhibit a method of computing the flow properties with a more nearly accurate model, (b) to see if the displacement on the skin would be related to the arterial wall displacement, and hence to pressure, velocity and flow rate of blood in the artery, a ...20051231056
effects of helicopter noise on pilots' hearing. 20051231074
[effect of x-rays on human adult skin explants]. 19751233920
[studies on the use of wheat rich in crude proteins in the feeding of broilers. 2. carcass yields and carcass composition].studies were made to investigate whether the the substitution of maize for high-protein wheat fed in combination with different protein in fattening rations to broilers would influence the carcass yields and chemical carcass composition of broilers. the described dietary regime was not found to have a significant influence on the different criteria of carcass composition (roaster carcass, flesh, abdominal fat, total proportion of utilizable parts) with the exception of the relative proportion of ...19751233971
[studies on the protein and amino acid metabolism of laying hens using 15n labeled casein. 15n concentration in the intestinal content and intestinal tissue in relation to the time of the last 15n administration].four laying hens with anus praeternaturalis were fed 15n casein for a period of 6 experimental days. each experimental bird thus received a 15n excess (15n') of 154.44 mg. 11.54 mg of 15n' were found in lysine 3.99 mg in histidine and 9.58 mg in arginine. 2 hens were slaughtered 48 hours after the last 15n dose; another 2 were sacrificed after 144 hrs. in this investigation the n content of the intestinal contents and in the proteins of the small and large intestine were determined. the average ...19751233975
[case of d/e translocation 45, xx, 13--, 18--, t(18q+, 13--)]. 19751234109
[current etiopathogenic view of idiopathic hypertrophic subaortic stenosis. study of 3 brothers with this disease]. 20051237159
the efficiency of aquocobalamine as an antidote in cyanide poisoning when given alone or combined with sodium thiosulfate.the antidotal activities of aquocobalamineacetates and sodium thiosulfate were tested in guinea pigs and cats. the animals were attached to artificial respirators throughout the experiment and were poisoned with a continuous infusion of sodium cyanide solution (4.1 mumol/kg.min nacn). the rate of action of each antidote was determined from the time taken for the hcn exhalation to drop below the level of 100 nmol/kg.min in quinea pigs, and to values below 25 nmol/kg.min in cats; the detoxifying c ...19751242295
editorial: misleading statistics. 20051247832
the detection of antibodies in human and animal filariases by counterimmunoelectrophoresis with dirofilaria immitis antigens.counterimmunoelectrophoresis revealed the presence of precipitin antibody in all of 6 dogs and the 1 cat infected with dirofilaria immitis and in the serum of 17 of 24 individuals living in a setting of hyperendemic subperiodic bancroftian filariasis. antigens used in the test were prepared from microfilariae and adult male d. immitis. some humans and animals had antibodies to both antigens while others had antibodies against microfilariae or adult worms only. the presence of soluble circulating ...19761262695
attenuated, streptomycin-dependent salmonella typhi oral vaccine: potential deleterious effects of lyophilization.four studies were done with streptomycin-dependent salmonella typhi as an oral, attenuated vaccine. studies 1 and 3 employed freshly harvested vaccine, whereas studies 2 and 4 involved lyophilized vaccine. five to eight doses (3 x 10(10)-10(11) organisms/dose) were given; oral streptomycin (1.0 g) was administered concomitantly in studies 2 and 3, with only two of the doses of vaccine in study 1, and was not given in study 4. no adverse reactions were encountered in 179 vaccinated men, and 94% o ...19761262709
hyperbaric oxygen exposures for intrahepatic abscesses produced in mice by nonsporeforming anaerobic bacteria.hyperbaric oxygen exposures were evaluated for treatment of progressive liver abscesses produced by intraperitoneal injection of combined cultures of fusobacterium necrophorum plus either bacteroides fragilis subsp. fragilis or fusobacterium nucleatum in a mouse model. infected control and hyperbaric oxygen-exposed mice were autopsied 5 or 6 weeks after inoculation of bacteria and were assigned numerical pathology scores according to the number and size of abscesses present. seventeen daily 3-h ...19761267430
rosamicin: in vitro activity against anaerobes and comparison with erythromycin.the in vitro activity of rosamicin was determined against 231 strains of anaerobic bacteria and compared with the activity of erythromycin against the same strains. rosamicin and erythromycin had similar activity against strains of peptostreptococcus and gram-positive nonsporeforming bacilli. rosamicin was somewhat more active against strains of peptococcus, clostridium, and gram-negative anaerobes. all strains of bacteroides fragilis tested were inhibited by 4 mug of rosamicin or less per ml, w ...19761267432
acute toxicity of mevinphos to gerbils. 20051273839
[test of degranulation of basophils and mast cells for detection of allergic diseases (literature survey)]. 19761274295
absolute configuration of 3-hydroxy fatty acids present in lipopolysaccharides from various bacterial groups.the absolute configuration of 3-hydroxy fatty acids has been studied, which are present in the lipopolysaccharides of the following bacteria: phodopseudomonas gelatinosa, rh. viridis, rhodospirillum tenue, chromobacterium violaceum, pseudomonas aeruginosa, bordetella pertussis, vibrio metchnikovii, vibrio cholerae, salmonella spp., escherichia coli, shigella flexneri, proteus mirabilis, yersinia enterocolitica and fusobacterium nucleatum. the 3-hydroxy acids were liberated by strong alkaline hyd ...19761278168
dofetilide, a novel class iii antiarrhythmic agent.dofetilide is a potent and selective class iii antiarrhythmic agent that is under development for the treatment of re-entrant tachyarrhythmias (ventricular tachycardia/ventricular fibrillation, atrial fibrillation/atrial flutter, and paraoxysmal supraventricular tachycardia). in animal studies, dofetilide selectively inhibits the rapid component of the time-dependent outward potassium current (ikr) and therefore increases the effective refractory period and action potential duration without affe ...19921279316
development and characterization of porphyromonas gingivalis-specific rat t-cell clones.porphyromonas gingivalis has been implicated as a major pathogen in periodontitis. to determine the role of t cells in the regulation of this disease, a method was developed for the generation and characterization of rat t-cell clones with antigen specificity to p. gingivalis whole cells. the clones studied so far demonstrated a t-helper (th) phenotype w3/13+, w3/25+, ox8- and ox22-. these t-cell clones proliferated in vitro in response to p. gingivalis, but not to other bacteria (prevotella int ...19921281976
regeneration of an adult peripheral nerve preparation in culture.the methods used to maintain the vagus nerve from the adult rat in culture and how regeneration is studied in this preparation are described. a hypothesis is presented on the triggering of the cell body reaction. it is suggested that this reaction is initiated by proteins synthesized in nonneuronal cells at the site of a nerve lesion. these proteins, referred to as regenerins, reach the nerve cell body by retrograde axonal transport, where they initiate the regeneration process.19921282333
[treatment and monitoring of primary hypothyroidism].treatment of primary hypothyroidism requires a long-term hormonal therapy with levothyroxine which restores a normal tsh value. in a series of 192 patients followed up for at least 3 years we tried to evaluate the variability of maintenance dosage and to analyse the factors predictive of replacement dosage. the l-t4 dosage varied from one individual to the other, from 0.6 to 3.2 micrograms/kg. the mean maintenance dosage (118 +/- 38 micrograms/day) was similar in men and women weight for weight, ...19921287777
prevalence studies of problematic behaviors in four-year-olds.prevalence rates for specific behaviors in the problem behavior questionnaire (pbq; behar & stringfield, 1974) and for four psychosomatically related behaviors (soiling, day and night wetting, and complaints about bodily aches) were estimated in a sample of 377 swedish 4-year-olds described by their parents (mainly mothers). the results showed that several of the behaviors classified as outgoing conduct problems were common in this age group; boys showed more problematic behaviors than girls, as ...20051287827
myocardial protection by retrograde cardioplegic perfusion in the presence of acute coronary artery obstruction. an experimental study.to investigate retrograde delivery of cardioplegic solutions as a means of enhancing myocardial protection in the presence of coronary artery occlusion, a two-part experimental model was devised. in part 1 (in vitro) the possibility of retroperfusing the entire myocardium during acute occlusion of the left anterior descending artery (lad) was assessed. in part 2 (in vivo) acute lad occlusion was performed in dogs, and during 2 hours of aortic cross-clamping crystalline cardioplegic solution was ...19921287835
soft-tissue management through effective patient subgingival bacterial control. 19921291435
expression and release of neuroregulators during development: monoamines and neuropeptides.the turnover of catecholamines (ca) was determined in the adrenal medulla and brain of rat fetuses and pups. in general we found a considerable increase soon after birth. the expression of mrna for ca-synthesizing enzymes was also considerably enhanced in the adrenals shortly after birth. furthermore, we demonstrated increased expression of neuropeptides after birth, increased synthesis of mrna encoding for neuropeptide y in the adrenals 24 h after birth; and considerable activation of the subst ...19921306802
hypoxic-ischemic damage in the neonatal brain: excitatory amino acids.perinatal brain damage is a major clinical problem. recent studies suggest that excitatory amino acids (eaas) may be important for the development of hypoxic-ischemic brain injury in the newborn. experimental work demonstrates that the immature brain is hypersensitive to the toxic effects eaa ('excitotoxicity'), hypoxic-ischemia is accompanied by an extracellular overflow of eaas and hypoxic-ischemic brain damage is reduced by eaa receptor antagonists. clinical investigations demonstrate the pre ...19921306803
the effect of 3 mouthrinses on plaque and gingivitis development.the aim of this study was to evaluate the effect of 3 mouthrinses, listerine antiseptic (thymol), peridex (chlorhexidine), perimed (povidone iodine and hydrogen peroxide), and a placebo (water) on the development of dental plaque and gingivitis, when used as the only oral hygiene procedure for 14 days. 71 subjects were entered into a randomized, double-blind study. at the baseline examination, papillary bleeding score (pbs), and plaque index (pi) were registered, after which subjects received su ...19921310096
microbiology of healthy and diseased periodontal sites in poorly controlled insulin dependent diabetics.a group of poorly-controlled insulin dependent diabetes mellitus (iddm) patients were examined in a cross-sectional design for total microbial levels, microbial incidence, and the percent levels of selected periodontal microorganisms. these organisms were selected on the basis of prior reports that associated them with either periodontal disease or health. one periodontally-healthy and one periodontally-diseased site were examined in each iddm patient. increased levels of the periodontal pathoge ...19921315389
use of adeno-associated virus as a general transduction vector for mammalian cells. 19921316261
analyzing phenotypic correlations in studies with selected lines. 19921317160
interactions of praseodymium and neodymium with nucleosides and nucleotides: absorption difference and comparative absorption spectral study.the interactions of praseodymium(iii) and neodymium(iii) with nucleosides and nucleotides have been studied in different stoichiometry in water and water-dmf mixtures by employing absorption difference and comparative absorption spectrophotometry. the 4f-4f bands were analysed by linear curve analysis followed by gaussian curve analysis, and various spectral parameters were computed, using partial and multiple regression method. the magnitude of changes in both energy interaction and intensity w ...20051317348
gabaa receptors control the excitability of neuronal populations. 20051317365
[molecular bases of chronic granulomatous disease--analysis of the involvement of cytosol factors for nadph oxidase].during the past 5 years, the discovery of cell-free superoxide generation system (bromberg y, pick e: cell immunol 88:213-221, 1984) has been revolutionized our understanding of phagocyte superoxide generation. using cell-free system, it was clarified that nadph oxidase for superoxide generation was comprised of components present in both the plasma membrane as well as in the cytosol. this oxidase could be kept inactive by keeping its components separated from each other within the cell and then ...20051317471
the use of dna probes to examine the distribution of subgingival species in subjects with different levels of periodontal destruction.the present investigation examined the distribution of 14 subgingival species at a total of 2299 sites in 90 subjects with different levels of periodontal destruction. subgingival plaque samples taken from the mesial aspect of each tooth were anaerobically dispersed, diluted and plated on non selective media. after anaerobic incubation, colonies were lifted to nylon filters and specific species detected using digoxygenin-labeled whole chromosomal dna probes. the mean total viable count for all s ...19921318331
new monoclonal antibodies for the detection of immediate early antigens of cytomegalovirus.two new monoclonal antibodies, cie-1 and cie-2, were developed for the rapid detection of human cytomegalovirus (hcmv) infection. they were found to be reactive with immediate early protein of hcmv in the nuclei of infected fibroblasts, as early as 3 hours post-infection. by radioimmunoprecipitation, cie-1 was found to react with a protein with an apparent molecular weight of 70,000, whereas cie-2 precipitated 2 proteins of 70,000 and 72,000 daltons, respectively. both monoclonal antibodies reco ...19921319172
subgingival temperature (iii). relation to microbial counts.the present investigation examined the relationship of selected bacterial species and subgingival temperature. 35 subjects were measured at 6 sites per tooth for clinical parameters and subgingival temperature. measurements were repeated for 21 subjects at 2 month intervals providing a total of 66 subjects visits. at each visit, subgingival plaque samples were taken from the mesial aspect of each tooth and anaerobically dispersed, diluted and plated on non-selective media. after anaerobic incuba ...19921321846
synergistic effect of pyrophosphate and sodium dodecyl sulfate on periodontal pathogens.our previous studies have shown that pyrophosphate (ppi), the anticalculus component of tartar-control dentifrices, inhibits the growth of organisms associated with coronal and root surface caries. the purposes of this investigation were to: 1) determine if periodontal pathogens are similarly susceptible to the growth-inhibitory properties of ppi; and 2) determine if combinations of pyrophosphate-sodium dodecyl sulfate (ppi-sds) inhibit growth synergistically. porphyromonas gingivalis, actinobac ...19921324304
femtosecond biology. 20031326353
role of porphyromonas gingivalis 40-kda outer membrane protein in the aggregation of p. gingivalis vesicles and actinomyces viscosus.porphyromonas gingivalis, an important pathogen in periodontitis, produces extracellular vesicles that aggregate with actinomyces viscosus cells. a 40-kda outer membrane protein (omp)-coding gene from p. gingivalis was cloned and the protein was found to be localized in these vesicles. the recombinant 40-kda omp did not show aggregation activity. however, affinity-purified antibody against the recombinant protein significantly inhibited aggregation of p. gingivalis vesicles with a. viscosus cell ...19921329700
effect of clavulanic acid, sulbactam and tazobactam on three different beta-lactamases from bacteroides uniformis, clostridium butyricum and fusobacterium nucleatum.the effect of three beta-lactamase inhibitors, clavulanic acid, sulbactam and tazobactam used in clinical practice were compared for their activity against purified beta-lactamases from bacteroides uniformis, clostridium butyricum and fusobacterium nucleatum. the enzymes from b. uniformis and c. butyricum were produced in fermenters under controlled growth conditions and the enzyme from f. nucleatum was produced in batch cultures. purification of the beta-lactamases was achieved by anion-exchang ...19921331018
correlation of haemagglutination activity with trypsin-like protease activity of porphyromonas gingivalis.porphyromonas gingivalis is a gram-negative anaerobic bacterium associated with various forms of periodontal disease. several characteristics of p. gingivalis are thought to contribute to its pathogenicity; these include haemagglutination and trypsin-like protease activity. previous studies suggest an association between haemagglutination and trypsin-like protease activity of p. gingivalis. to investigate this, two complementary quantitative experimental approaches were taken. five independent m ...19921332663
sensitization of oral bacteria in biofilms to killing by light from a low-power laser.biofilms of streptococcus sanguis, porphyromonas gingivalis, fusobacterium nucleatum and actinobacillus actinomycetemcomitans were prepared on the surfaces of agar plates and a number of compounds were screened for their ability to sensitize bacteria in these biofilms to killing by light from a 7.3 mw helium/neon (he/ne) laser. toluidine blue o and methylene blue enabled detectable killing of all four target organisms after exposure to he/ne light for 30 s. aluminium disulphonated phthalocyanine ...19921334649
bacterial concentration fluorescence immunoassay (bcfia) for the detection of periodontopathogens in plaque.a bacterial concentration fluorescence immunoassay (bcfia) was developed to rapidly detect periodontopathic bacteria in human plaque samples. the bcfia utilized fluorescent-tagged monoclonal antibodies (mabs) directed against the lipopolysaccharide of selected gram-negative bacteria. microorganisms identified in plaque using the bcfia included actinobacillus actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, and fusobacterium nucleatum. the immunoassay procedure involved com ...19921336047
dna probe and enzyme analysis in periodontal diagnostics.recent research in periodontology has indicated that a finite number of bacterial species are associated with periodontal disease. this has generated the hypothesis that periodontal disease is essentially an infection due to one or more of the putative periodontopathogens; i.e., the specific plaque hypothesis (sph). this microbial specificity paradigm has already changed the way researchers and some clinicians view periodontal disease. the clinician must heed several cautions signs, however, if ...19921336048
antibacterial efficacy of root canal medicaments.the antibacterial efficacy of four endodontic medicaments was studied in vitro. calcium hydroxide (calacept), camphorated parachlorophenol (cpcp), cresophene, and 2% iodine-potassium iodide (iki) were tested against four anaerobic microorganisms, streptococcus mutans, peptostreptococcus anaerobius, porphyromonus gingivalis and fusobacterium nucleatum, for 10 or 15 min. iki was effective only against f. nucleatum and p. gingivalis, and the others were effective against all four microorganisms.19921337555
effect of beta-lactamase inhibitors on beta-lactamases from anaerobic bacteria.three beta-lactamase inhibitors in clinical use--clavulanic acid, sulbactam and tazobactam--were investigated for their activity on beta-lactamases from bacteroides uniformis, clostridium butyricum and fusobacterium nucleatum. purification of the beta-lactamases was carried out by anion-exchange chromatography, gel filtration and fplc. the inactivation of beta-lactamase activity was determined spectrophotometrically with nitrocefin as substrate. various concentrations of the inhibitors were prei ...19921338315
effect of the vibratory acoustic stimulation on fetal heart rate patterns of premature fetuses.the purpose of this study was to examine the heart rate patterns before and after a standardized external vibratory acoustic stimulation in a group of 24 healthy premature fetuses at 32-35 weeks gestational age. fhr was analysed on line by sonicaid computer system 8000. a significant increase in the number of accelerations and an increase of variation after stimulus were observed. all other fhr patterns such as baseline, high and low episodes did not change significantly.20061346598
release of endogenous noradrenaline from the vascularly perfused rat stomach in vitro: modulation by pre- and postsynaptic adrenoceptors.we developed an experimental in vitro model to detect a very small amount of endogenous noradrenaline (na) released from the rat gastric sympathetic nerve terminals. the stomach was perfused via celiac artery with modified krebs-ringer solution containing 10 mm pargyline and 0.1% bovine serum albumin at a constant flow of 4 ml/min. the right greater splanchnic (spl) nerve (preganglionic nerve of the gastric sympathetic nerve) was stimulated electrically with square-wave pulses of 2 msec duration ...19921346643
antigen-receptor complex stimulation triggers protein kinase c-dependent cd11a/cd18-cytoskeleton association in t lymphocytes.although it is well accepted that intercellular adhesion involving the cd11a/cd18 (lfa-1) complex is critical in a wide array of t cell-dependent processes, recent demonstrations of an lfa-1 high avidity state, induced by triggering the t cell receptor (tcr) complex, has raised questions about the intracellular signals generated and molecular events leading to effective cell coupling, as well as their orderly sequence. in this study, we assessed the effects of t cell activation on the actin-base ...20061346786
thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. a study in parabiotic mice.this study was designed to resolve the long standing controversy as to whether hematogenous precursors or resident intrathymic precursors maintain thymocytopoiesis in postnatal life. the kinetics of thymic chimerism was examined over a 21-wk period in 105 pairs of nonirradiated, thy-1-alloantigen-disparate, parabiotic b10.s mice. thymic chimerism reached reached maximum levels of 25% in the thy-1b and 16% in the thy-1a partners (mean 20.5% and 9.8%, respectively) 6 to 7 wk after parabiotic union ...20061347301
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