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the indirect rat mast cell degranulation test reconsidered.the indirect rat mast cell degranulation test for the detection of human reaginic antibodies was reinvestigated. when the mast cells were incubated with human reaginic serum at concentrations exceeding approximately 3%, a massive, non-specific histamine release occurred, irrespective of the presence or absence of allergen. at tolerated serum concentrations (below 3%), the allergen concentration did not influence the release process. we conclude that the indirect rat mast cell test is not applica ...197990655
the expression of a human b-lymphocyte antigen and surface membrane immunoglobulin by lymphoid cells from patients with lymphocytic lymphoma, multiple myeloma and benign monoclonal gammapathy. 197990449
the elephant man. 197990342
polyribonucleotide inhibition of ribonucleic acid directed deoxyribonucleic acid polymerase of mouse mammary tumor (type b) virus and simian sarcoma (type c) virus. 197990331
fetal heart-rate monitoring. 200190290
[machine method of applying a sorbent layer to chromatographic plates]. 200090206
the effect of rectal examination on serum acid phosphatase. 200090146
axonal transport of a brain-specific protein in the optic fibres of octopus vulgaris. 200090124
effects of arachidonic acid and its metabolites on antigen-induced histamine release from human basophils in vitro. 197990097
distribution of myosin isoenzymes among skeletal muscle fiber types.using an immunocytochemical approach, we have demonstrated a preferential distribution of myosin isoenzymes with respect to the pattern of fiber types in skeletal muscles of the rat. in an earlier study, we had shown that fluorescein-labeled antibody against "white" myosin from the chicken pectoralis stained all the white, intermediate and about half the red fibers of the rat diaphragm, a fast-twitch muscle (gauthier and lowey, 1977). we have now extended this study to include antibodies prepare ...197990047
cea-like antigens in different histologic types of human lung carcinoma.comparative studies on the presence and immunological reactivity of cea and cea-like antigens in lung and digestive tract cancers were performed. specific goat and rabbit anti-cea immune sera were used. immunofluorescence studies revealed in histologically different types of the lung carcinomas the presence of the cross reacting antigen with classical cea. absorption procedures, and double diffusion tests have shown the existence of two at least antigenic determinants in cea molecule: 1. the det ...197989630
beta-lactamase inhibitors--a novel approach. 199989565
continuous subcutaneous insulin infusion or subcutaneous insulin injections. 199989550
vitiligo patterns simulating autoimmune and rheumatic diseases.several variants of generalised vitiligo can be recognised by their cutaneous distribution. in some, certain anatomical regions--e.g., hands--are predominantly affected while the cutaneous depigmentation in other variants shows a similar anatomical distribution to that of the internal structures affected in some of the autoimmune and rheumatic diseases. five patients have been seen, and three described by others, with vitiligo affecting skin of eyelids and lower front of neck, reminiscent of the ...199989452
deaths of infants after triple vaccine. 199989408
hermann zondek. 199989329
effect on bone of withdrawal of oestrogen therapy. 199989300
plasma 1,25(oh)2 vitamin d concentrations in nutritional osteomalacia. 199989299
preoperative haemoglobin as predictor of outcome of diabetic amputations.simple factors which may serve as predictors of the success or failure of amputations in the feet were examined in 59 consecutive diabetics. age, sex, method of diabetic control, smoling, presence of neuropathy or peripheral pulses, preoperative blood-urea, and temperature did not correlate with success of amuptations. the average preoperative white-cell count and blood-sugar were higher in the failure group (p less than 0.01 and p less than 0.05 respectively), but there was considerable overlap ...199989280
[determination of serum immunoglobulin level in patients with immunologic deficiency by thermistography]. 199989257
new screening test for colorectal cancer developed in canada. 199989207
demonstration of the existence of small local circuit neurons in the golgi-stained primate substantia nigra. 200189001
[post-extrasystolic and post-pacing potentiation. ii. study by means of systolic time intervals in man]. 197888948
fatal leishmaniasis in renal-transport patient. 199988649
resistant vibrio cholerae el tor in tanzania. 197988577
electroimmunoassay of factor ix in patients with liver damage and vitamin k unresponsive coagulation disorder.factor ix antigen and activity were assayed in a group of patients with liver disease and in a group of patients in coumarin therapy. in patients with liver disease there was a similar decrease in activity and antigen. on the other hand factor ix activity is decreased in coumarin treatment with factor ix antigen remaining normal. factor ix electrophoretic mobility in liver disease is normal.200188391
extramedullary haematopoiesis in thrombotic thrombocytopenic purpura.extramedullary hematopoiesis was detected in routine sections of spleen and liver from two patients with thrombotic thrombocytopenic purpura (ttp). in patients with other types of hemolytic anemia and in normal persons, extramedullary hematopoiesis was not found in spleen or liver. the results of this study raise the possibility that ttp may fit within the myeloproliferative category, perhaps representing an acute variant of di-guglielmo syndrome.200188388
effects of h-reflex conditioning upon the contralateral alpha motoneuron pool.h-reflex recovery curves have been elicited by subliminal conditioning stimuli applied to the ipsilateral and contralateral posterior tibial nerves in 10 healthy female subjects. in both types of recovery curve there was clear evidence of a period of facilitation in the ipsilateral soleus motoneuron pool 75-250 msec after the conditioning stimulus. these results indicate the bilateral nature of the facilitation and show it to be most probably produced by stimulus-evoked inputs as opposed to twit ...200188332
prostaglandin e1-induced latent epileptogenic foci.suprafusion of 125 microliter 6% kcl solution over the visual cortex of rabbits 2-24 h after they suffered a prostaglandin (pg) e1-induced epileptic seizure was found to cause a recurrence of seizure activity. the initial seizure was induced by the cortical suprafusion of pge1 over the left visual cortex of pg transport inhibitor-pretreated rabbits. control animals that were not pretreated with pg transport inhibitors (bromcresol green or probenecid), or received suprafusion of saline or pgf2 al ...197988324
igd myeloma protein with "unreactive" light chain determinants.serum from a patient with multiple myeloma showed a monoclonal protein, classified by immunoelectrophoresis as igd. immunofixation electrophoresis and immunoelectrophoresis failed to demonstrate a precipitation reaction between the paraprotein and antisera to immunoglobulin light chains. the light chains of the monoclonal protein, immunologically inaccessible in the intact molecule, reacted with anti-lambda chain antisera only after reduction and alkylation of the paraprotein. moreover, interpre ...200188283
[the antibacterial action on dental plaque of antibiotics used in dentistry. 2. in vitro experiments on streptococcus mutans, staphylococcus aureus and fusobacterium nucleatum (author's transl)]. 197788239
individual mice recognize the complex nature of h-2 antigens; unexpected reactions (anti-kk) in anti-balb/c-h-2d sera produced in the balb/c-h-2db mutant. 200188092
clinical significance of biologic markers: memorial hospital experience. 200188073
the hazards of anesthesia and surgery in bleomycin-treated patients. 200188070
new consultant contract. 200187861
surgical wound sepsis. 200187737
mutagenicity in urine of nurses handling cytostatic drugs. 197987722
progression of diabetic nephropathy.although deterioration of renal function in diabetic nephropathy varies considerably from one diabetic to another, its rate is constant in individuals. for each patient there is a linear relation between period (months) which elapses from the time serum creatinine becomes greater than 200 mumol/l and the inverse the inverse of the serum-creatinine. the observation is of practical importance in predicting the time at which end-stage renal failure will develop, so that treatment can be planned in ...200086831
the results of prostatectomy: a symptomatic and urodynamic analysis of 152 patients.there were 152 patients with prostatism investigated by inflow cystometry and pressure flow analysis of micturition before and after elective prostatectomy. many symptoms attributed to obstruction were found to be owing to bladder instability, which was demonstrated in 60 per cent of the patients. the symptomatic improvement postoperatively was accompanied by a decrease in the incidence of instability to 25 per cent. the repeat urodynamic studies and symptom analysis demonstrated a surgical succ ...200086617
tissue cea in premalignant epithelial lesions and epidermoid carcinoma of the uterine cervix: prognostic significance.carcinoembryonic antigen (cea) was studied by the indirect triple-bridge immunoperoxidase method in formalin-fixed paraffin-embedded tissue specimens from 191 patients with premalignant epithelial lesions or epidermoid carcinoma of the uterine cervix treated 12 years ago. the frequency of tissue cea positivity was found to increase with advancing clinical disease in the following manner: mild dysplasia, 25%; severe dysplasia, 37%; carcinoma in situ, 60%; invasive carcinoma stage i, 60%; stage ii ...200086522
an investigation into the antigen-specificity of transfer factor in its stimulatory action on lymphocyte transformation.dialysable transfer factor (tf) was prepared from the buffy-coat cells of donors with known cell-mediated reactivity to tuberculin (ppd), streptococcal protein (sksd) and diphtheria toxoid (dt). the effect of such preparations on the transformation by these antigens of lymphocytes from tuberculin-negative donors was investigated. transformation was determined as incorporation of tritiated thymidine. the concentrations of sksd and dt were adjusted for different lymphocyte donors so as to give, in ...200086502
[intratypical antigenic differentiation of poliovirus strains circulating in mali by means of cross-adsorbed sera].the intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in mali in 1975-1976 was performed. the method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. all the examined strains of serologic types i, ii, and iii were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". quantitative differences in the ant ...197886237
immunochemical characterization of the plasmin-antiplasmin system. basis for the specific detection of the plasmin-antiplasmin complex by latex agglutination assays. 197985679
diagnostic value of biochemical analysis of pleural effusions. carcinoembryonic antigen and beta 2 microglobulin.pleural effusions from 105 patients with malignant and nonmalignant diseases were examined for tumor cells, content of cea, beta2 microglobulin, ceruloplasmin, alpha2 macroglobulin, orosomucoid, lysozyme, and hexosaminidase. only cea and beta2 microglobulin determinations were of diagnostic value. cea concentrations greater than 11 ng/ml were found only in malignant effusions. beta 2 microglobulin values were increased in pleural effusions due to lymphoma or immune diseases. measurement of cea a ...199985412
solid phase indirect radioimmunoassays for the rapid diagnosis of sindbis virus antigen.indirect radioimmunoassays have been developed for the rapid detection of sindbis virus. dilutions of sindbis virus from tissue culture fluids have been immobilized and allowed to react with rabbit anti-sindbis virus antibodies. the bound antibodies were assayed either by 125i-labelled anti-rabbit igg-antibodies or alternatively by addition of human complement and 125i-labelled anti-human c1q antibodies or 125i-labelled protein a.197884855
localization of nors in chromosomes of mouse cell lines by a combined 33258-hoechst and ag-staining technique. 197984805
the allergenic structure of allergen m from cod. iii. studies on the antigenicity of long-sequence peptides.fragments tm 1 (75 amino acid residues) and tm 2 (38 amino acid residues), and 3 other polypeptides (range 16-25 amino acid residues) of allergen m from cod were shown to be active in rabbit igg-mediated reactions. the same peptides were previously found to possess reactivity in ige-mediated reactions, thus suggesting a structural relationship between their antigenic and allergenic determinants.197984803
cross-reaction between the mycelial galactomannas of three hormodendrum strains and the mannans of two candida albicans strains of different serotypes, a and b.cross-reactivity between galactomannans of three representative hormodendrum strains, h. pedrosoi ifo 6071, h. compactum ifo 6726, and h. dermatitidis ifo 6421, and the mannans of two candida strains, c. albicans nih a-207 (serotype a) and c. albicans nih b-792 (serotype b), were investigated by means of agar-gel double diffusion, quantitative preciptin reaction, and passive cutaneous anaphylaxis. the following results were obtained. (i) antisera to whole cells of three hormodendrum strains were ...197984792
the effect of mixed phosphatidylcholine liposomes on beef heart cytochrome c oxidase [proceedings]. 197884573
sugar inhibition of oral fusobacterium nucleatum haemagglutination and cell binding. 197944185
anaerobic pulmonary infections.the main cause of anaerobic pulmonary infections is aspiration of saliva, upper airway secretions or gastric content. predisposing conditions include prominent dental disease, chronic upper respiratory tract infections and reduced consciousness. fusobacterium nucleatum, bacteroides melaninogenicus and anaerobic gram-positive cocci are the most frequently encountered organisms. the clinical presentations are lung abscess, lung gangrene and empyema, which all tend to take a slow and indolent cours ...197937594
acupuncture: its neurophysiological basis: an anaesthetist's foreword. 197829773
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