Publications

complications and inappropriate use of minitracheostomy.		2008	2596687
[a clinicopathological study of recurrent gastric cancer cases treated by a resection of the remnant stomach].	seventeen cases of a recurrent gastric cancer that were treated by a resection of the remnant stomach have been studied retrospectively. for first management 12 cases were given a billroth 2 procedure, 4 cases a billroth 1 procedure and 1 case a fundectomy. for the recurrent cancer, 13 cases were given a total resection of the gastric remnant and 4 cases a partial resection. the overall mortality rate was 12% and the survival rate was 58% at 1 year, and 8% at 5 years. we thus have concluded that ...	2008	2593232
[changes in lymphocytes in acute suppurative-destructive lung diseases].	a study of the content of lymphocytes and their populations, indices of intracellular viral involvement of the lymphocytes in 32 patients with acute purulent-destructive pulmonary diseases and 46 healthy persons revealed an increase of the percent of non-viable lymphocytes containing viral inclusions. viral involvement of lymphocytes is considered one the leading causes of increased lymphocyte death.	2008	2588523
discipline without punishment--part i.		1999	2586930
not for specialists only--caring for patients with spinal cord injuries.		2002	2586900
differential expression of the il-2 receptor subunits, p55 and p75 on various populations of primary peripheral blood mononuclear cells.	unstimulated pbl were examined for expression of il-2r subunits, il-2rp55 and il-2rp75, by two-color flow cytometric analyses using mab. nkh-1+ non-t non-b cells expressed il-2rp75 but not il-2rp55, and the il-2rp75 sites on purified nkh-1+ cells were determined to be 1630 sites/cell by binding of 125i-labeled tu27 mab specific for il-2rp75. in the cd4+ t cell population, il-2rp55+ cells were significantly detected, but little or marginally of the il-2rp75+ cells. however, il-2rp75+ cells were s ...	2008	2584707
characterization of coagulase-negative staphylococci by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblot analyses.	coagulase-negative staphylococci are important nosocomial pathogens. at present, no wholly satisfactory typing scheme exists for these organisms. therefore, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) and immunoblotting were assessed as characterization methods. a total of 100 type strains and nontyped isolates representing nine species of coagulase-negative staphylococci were analyzed. each species had a reproducible, characteristic whole-cell banding pattern when analy ...	1989	2584373
recovery from coma that results as a complication of cardiac arrest followed by cardiopulmonary bypass.	many possible complications are associated with cardiopulmonary bypass. they are similar to the risks accompanying most surgical procedures and include stroke, renal failure, and death. this potential for complication increases when bypass exceeds 2 hours and rises sharply when pump time is prolonged more than 3 to 4 hours. one group of serious complications is major neurologic disorders. the risk of significant cerebral dysfunction, that is, severe focal stroke or coma, is about 1%, and this ri ...	2008	2584045
lateralization of the hoffmann reflex from the long flexor thumb muscle in right- and left-handed normal subjects.		2008	2583947
lipid keratopathy in rabbits. an animal model system.	rabbits rendered hypercholesterolemic on a high cholesterol diet while subjected to corneal suture placement to induce neovascularization made useful models for qualitatively and quantitatively studying lipid keratopathy. forty rabbit eyes were subjected to placement of four sutures located between 1 and 4 mm from the limbus. the neovasculature grew at a constant rate of 0.24 mm/day, unaffected by serum cholesterol levels. rabbits fed cholesterol prior to surgery were the earliest to display lip ...	1985	2581537
leukocyte tubuloreticular inclusions in reye's syndrome.	tubuloreticular inclusions (tri) have been observed in the rough endoplasmic reticulum of blood lymphocytes and monocytes in two cases of reye's syndrome initiated by influenza infections. tubuloreticular inclusions are seen in these mononuclear leukocytes during the acute phase of illness, but not during convalescence. since tri have been demonstrated in peripheral mononuclear leukocytes in patients with acquired immunodeficiency syndrome, systemic lupus erythematosus, and certain viral infecti ...	1985	2581524
self reactive delayed type hypersensitivity (dth) induced in mice by syngeneic lymphoblasts.	normal and x-irradiated a mice injected with syngeneic concanavalin a (con a)-induced lymphoblasts revealed after challenge with syngeneic lipopolysaccharide (lps)-induced lymphoblasts delayed type hypersensitivity (dth) measured both by footpad swelling and by 125iudr accumulation. mice injected with allogeneic con a-induced lymphoblasts and challenged with syngeneic lps-induced lymphoblasts or vice versa, also generated an appreciable dth response. in contrast, con a-induced blast cells of hum ...	1985	2580776
lysis of lymphoma cells by autologous and allogeneic natural killer cells.	studies were undertaken to determine whether natural killer (nk) cells would lyse autologous and allogeneic lymphoma cells. when large granular lymphocytes, which are known to mediate nk activity, were enriched from peripheral blood and used as effector cells, they lysed autologous lymphoma cells of all of eight patients tested, and those of healthy donors lysed lymphoma cells of all of ten patients tested. the addition of interferon to the culture medium enhanced their cytotoxicity in three of ...	2008	2578838
the process of baculovirus deproteinization.	the localization and function of alkaline protease inside the supervirion capsids (granules, inclusion bodies) of granulosis virus and nuclear polyhedrosis virus have been determined with the help of electron microscopy. it has been shown that deproteinization of baculoviruses proceeds in several steps. the first two stages (the release of virus from supervirion capsids and the release of nucleocapsids from the internal and external coats, were accomplished in the intestine of the insects, while ...	1989	2576597
recognition of fusobacterium nucleatum subgroups fn-1, fn-2 and fn-3 by ribosomal rna gene restriction patterns.	dna from representative strains of fusobacterium nucleatum subgroups fn-1, fn-2 and fn-3 was digested with restriction enzymes ecori and taqi and the electrophoretically separated fragments hybridized with a 32p-16s rrna gene probe from e. coli. the rrna gene restriction patterns from dna digested with either enzyme allowed the clustering of strains into the three subgroups. however, taqi digested dna yielded a wider distribution of taxonomically useful bands (ca 0.65 +/- 14.3 kbp) and the patte ...	1989	2575556
diabetes and schizophrenia.		2008	2574803
first assisting in cataract surgery: program results.	1. this program was established to teach non-physicians to first assist in cataract surgery, since third party payors would no longer pay for physicians to first assist. 2. among the advantages to utilizing non-physician first assistants are: availability, reliability, familiarity with instruments and equipment, and quality of service. 3. the questionnaire results confirm that the advantages of having non-physician first assistants far outweigh the disadvantages.	2008	2566208
drug advertising.		2008	2566076
utilization of amino acids and peptides by fusobacterium nucleatum.	fusobacterium nucleatum strains atcc 10953, fevl, f1, f3, and f6 utilized amino acids, in particular glutamate, histidine, and aspartate were common to all strains. strain differences were observed in the utilization of threonine, serine, lysine, tyrosine, and methionine, and only strain atcc 10953 utilized all these amino acids. the glutamate and histidine pools were in all cases fully depleted before the other amino acids were attacked and at the same time all strains except 10953 started to u ...	1989	2565597
treatment of mouse thymus cells with phosphatidylinositol-specific phospholipase c preferentially abrogates their reactivity with autoantibodies to the thy-1 antigen.	thy-1 molecules have been shown to become anchored to the membrane of thymocytes and of t-cells via a phosphatidylinositol link. in the present study the intensity of immunofluorescent staining of mouse thymus cells by monoclonal xenoantibodies and alloantibodies specific for the thy-1.2 determinant was significantly reduced following exposure of the cells to phosphatidylinositol-specific phospholipase c (pi-plc). the majority of the pi-plc-treated thymus cells retained, however, some reactivity ...	1989	2563957
absorption of human growth hormone from the rat lung.	recombinant methionyl human growth hormone (hgh) was administered intratracheally to adult rats, and serum concentrations of immunoreactive hgh were measured for up to 24 h. the mean absolute bioavailability was approximately 36% after 18h and was similar for doses of 0.75, 1.5, and 3 mg/kg. peak serum hgh concentrations occurred at approximately 6 h after dosing. tritiated hgh (3h-hgh) was used to follow the clearance of hormone from the lungs. disappearance was linear with time and by 24 h app ...	1989	2562650
unlikely association between clinically apparent herpesvirus infection and coronary incidence at older ages. the framingham heart study.	experimental studies in chickens have shown a relationship of a herpesvirus to atherosclerosis. the hypothesis of an association in humans was tested by using data on the history of cold sores and other manifestations of herpes infections reported by 658 male and 919 female participants (ages 58 to 89) in the framingham heart study from 1977 to 1979 and on the prevalence and subsequent 6-year incidence of coronary heart disease (chd). approximately 40% of the men and 52% of the women reported a ...	1989	2556099
lectinlike interactions of fusobacterium nucleatum with human neutrophils.	fusobacterium nucleatum expresses lectinlike adherence factors which mediate binding to a variety of human tissue cells. adherence is selectively inhibited by galactose, lactose, and n-acetyl-d-galactosamine. in this study, adherence of f. nucleatum to human peripheral blood polymorphonuclear neutrophils (pmns) was investigated. the results indicated that the fusobacteria adhered to live and metabolically inactivated or fixed pmns. adherence of f. nucleatum resulted in activation of pmns as dete ...	1989	2553609
[gene cloning of an actinobacillus actinomycetemcomitans y4 antigen that reacts to peripheral blood sera in advanced destructive periodontitis patients].	actinobacillus actinomycetemcomitans (a.a.) has been implicated in the etiology of juvenile periodontitis and also of advanced destructive periodontitis (adp). it has been reported that the levels of the igg antibody against the a.a. in the peripheral blood sera of the adp patients were often high as well as those against the bacteroides gingivalis. to clone the genes of antigen reactive to the sera of the adp patients, we constructed a phage library of the a.a. strain y4 dna in lambda l47, whic ...	1989	2533606
sidewinder retention sutures for closure of the abdominal wall.	reported herein, a technique of sutures placement that avoids certain objections to the traditional style of retention sutures is described. it is particularly useful in patients undergoing repeated laparotomy and in patients whose wounds are closed in a layered manner and who are at high risk for dehiscence.	2008	2525819
bactericidal concentrations of chlorhexidine-digluconate, amine fluoride gel and stannous fluoride gel for subgingival bacteria tested in serum at short contact times.	in vitro inhibitory and bactericidal concentrations in serum of chlorhexidine-digluconate, amine fluoride gel, stannous fluoride gel, stannous fluoride, metronidazole and amoxicillin were determined against bacteroides gingivalis, bacteroides intermedius, fusobacterium nucleatum, actinobacillus actinomycetemcomitans and capnocytophaga sputigena. the minimal inhibitory concentration was assessed by the agar dilution technique. the killing curves and minimal bactericidal concentration of the antim ...	1989	2524581
[diagnosis of obesity: psychological aspects].		2008	2519405
[central pontine myelinolysis, associated with hyperglycemia and hyponatremia: a clinical case].	a 68 year old diabetic male was admitted with hyponatremia and developed a "deafferentiation" syndrome. central pontine myelinolysis was suspected after clinical, eeg and brain cat scan. the diagnosis was confirmed at necropsy. the pathogenesis, clinical manifestations and treatment of this disorder are discussed.	1989	2519379
[multiple sclerosis in health care in our country: electrophysiological, immunological and clinical analysis].	among 70 patients referred for suspected multiple sclerosis (ms) a total of 40 met criteria for definite (17), likely (12) or possible (11) diagnosis of the disease. visual evoked potentials provided evidence of cns lesion in 13 cases. abnormalities of somatosensory evoked potentials, particularly on stimulation of the posterior tibial nerve, were present in 90% of patients. brainstem auditory evoked potentials were of little use, contributing to diagnosis of one subclinical lesion; they were no ...	2008	2519355
ethics in the nursing curriculum for all levels of education: baccalaureate, masters' and doctoral.		2008	2516597
intravenous fat emulsion acutely suppresses neutrophil chemiluminescence.	the immediate effect of intravenous fat emulsion on neutrophil oxidant release was studied. opsonized nonencapsulated s. aureus was used to stimulate neutrophil activity. luminol enhanced chemiluminescence was followed over 15 min and recorded as peak output (p; mv), integral under the curve (i; v-sec) and rate of increase (r; mv/sec). eighteen chronically ill patients receiving glucose based total parenteral nutrition were studied before and after a 4- to 6-hr test infusion of 500 ml of 10% fat ...	2008	2515308
[teratogenic effect of thiotepa].		2008	2493184
[flumazenil].		2008	2493168
hemocyte monophenol oxidase activity in mosquitoes exposed to microfilariae of dirofilaria immitis.	monophenol oxidase (mpo) activity in hemocytes collected from aedes aegypti liverpool strain and aedes trivittatus intrathoracically inoculated with saline alone, inoculated with dirofilaria immitis microfilariae (mff), or from uninoculated mosquitoes was compared using a radiometric tyrosine hydroxylation assay. hemocyte mpo activity in mff-inoculated (= immune-activated) mosquitoes was significantly increased at 24 hr postinoculation (pi) in a. aegypti and at 6, 12, and 24 hr pi in a. trivitta ...	1989	2493084
[chemiluminescence response and phagocytic activity of murine polymorphonuclear leukocytes to various species of oral bacteria].	polymorphonuclear leukocytes (pmn) are predominant cells in the gingival crevice and saliva, and may play an important role in oral bacteria. murine peritoneal pmn was used and stimulated with 9 genera, 17 species of oral bacteria, including cariogenic and periodontal pathogens. the pmn response to the bacteria was measured by the luminol mediated chemiluminescence (cl) response and phagocytic activities, and the activities of lysozyme in the reaction medium after the cl response were also measu ...	1989	2489336
ovine and bovine abortion associated with fusobacterium nucleatum.		1989	2488355
characterization of coaggregation between bacteroides gingivalis t22 and fusobacterium nucleatum t18.	bacterial adherence is a key factor in the colonization of the oral ecosystem, yet little is known about the mechanisms by which the pathogen bacteroides gingivalis adheres in the periodontal environment. we examined the ability of strains of b. gingivalis to coaggregate with selected microorganisms isolated from the subgingival microbiota of the cynomolgus monkey. a strong interaction was demonstrated between strains of b. gingivalis and fusobacterium nucleatum, whereas less pronounced or no in ...	1989	2478473
[immunochemical study of the lipopolysaccharides of yersinia enterocolitica serovars o5 and o5.27].	y. enterocolitica lipopolysaccharides (lps), serovars o5 and o5.27, have similar antigenic specificity. the lps of serovar o5.27 has been shown to contain no factor o27. residual alpha-l-rhamnose, glycosylated by d-xylulose, has been found to play an important role in the formation of factor o5, common for both serovars.	1988	2469272
identification of a galactose-binding lectin on fusobacterium nucleatum fn-2.	a previous study has suggested that fusobacterium nucleatum fn-2 contains a galactose-binding protein (lectin) on the cell surface (p. a. murray, v. matarese, c. i. hoover, and j. r. winkler, fems microbiol. lett. 40:123-127, 1987). in the present study, the molecular specificity and size of this lectin were investigated by several techniques. whole-cell affinity chromatography with asialofetuin covalently coupled to sepharose 6mb demonstrated that 81% of 3h-labeled f. nucleatum were specificall ...	1988	2451642
[biochemical studies on peripheral nervous system].		2007	2447920
spatial resolution of neuromagnetic records: theoretical calculations in a spherical model.	spatial resolution of magnetoencephalography (meg) was studied by computer simulations using a spherical conductor model for the head. the accuracy obtainable in the absolute location of a dipole was found by calculating the confidence limits for source location in 3 dimensions. the accuracy in determining the relative locations of two sources was estimated by calculating the smallest shift in source location that could be detected with statistical significance. the results were used to illustra ...	2008	2446847
the effects of nitrous oxide on p300 and reaction time.	this experiment investigated the effects of 3 concentrations (15%, 25% and 35%) of nitrous oxide (n2o) on reaction time (rt) and p300 latency and amplitude. ten subjects responded to visually presented male or female names in an oddball paradigm with accuracy controlled at a high level. the results were analysed on a single-trial basis. nitrous oxide increased both rt and p300 latency in a dose-related manner and these variables showed a strong between-dose correlation (r = 0.67). nitrous oxide ...	2008	2446836
respiratory syncytial virus fusion glycoprotein: further characterization of a major epitope involved in virus neutralization.	competition experiments and biological assays with a panel of 15 monoclonal antibodies confirmed the presence of at least four antigenic sites on the fusion protein of human respiratory syncytial virus, three of which were involved in virus neutralization. one antigenic site, recognized by two strongly neutralizing antibodies, was conserved after reduction and denaturation and shown by immunoblotting to be localized on the f1 fragment of the fusion protein. cleavage of this protein with staphylo ...	1987	2446731
ribosomal ribonucleic acid gene restriction patterns as potential taxonomic tools.	deoxyribonucleic acid from 41 different bacterial species (including gram-negative and gram-positive species) were cleaved by different restriction endonucleases, electrophoresed in agarose and transferred to nylon filters. the dna fragments carrying rrna genes (rdna) were localized by hybridization with a 32p-labelled escherichia coli 16 + 23s rrna probe. a pattern of hybridized fragments was obtained for each dna tested. within a bacterial species (defined as a dna hybridization group), one or ...	1986	2446639
conformations of intermediates in the folding of the pancreatic trypsin inhibitor.	intermediates in the folding pathway of the bovine pancreatic trypsin inhibitor (pti) have been examined by 1h nuclear magnetic resonance (n.m.r.). the intermediates were trapped during the reoxidation and consequent refolding of reduced pti by alkylating free thiols; each intermediate contained different disulphide linkages. the n.m.r. spectra reveal that conformational features of the native protein are present in the intermediate containing just one of the three normal disulphide linkages (30 ...	1987	2443711
transient outward currents and changes of their gating properties after cell activation in thrombocytes of the newt.	1. the electrical properties of the cell membrane of thrombocytes in the newt, triturus pyrrhogaster, were studied using the whole-cell variation of the patch-electrode voltage-clamp technique. 2. in medium containing ca2+ (1.8 mm), activated thrombocytes became round and then spread on the glass. activation of thrombocytes was inhibited by the removal of external ca2+ and addition of 1 w/v% albumin to the external media. 3. for thrombocytes kept in the resting state, depolarizations more positi ...	2008	2443665
possible existence of a novel amphipathic immunostimulator in the phenol-water extracts of mycobacteriaceae.	the extracts having diverse immunostimulating activities were obtained as a water-phase fraction from four bacterial species representing the 4 genera (mycobacterium, nocardia, gordona, and rhodococcus) of mycobacteriaceae by the phenol-water method, which is commonly used for extraction of endotoxic lipopolysaccharides (lps) from gram-negative bacteria and amphipathic substances from gram-positives. these fractions, especially those of g. aurantiaca and r. terrae, showed strong stimulatory effe ...	1987	2441233
differential expression of class ii (dr & dq) antigens by human gingival langerhans' cells and keratinocytes in vitro.	the expression of the class ii products dr and dq on human gingival epithelium was examined using immunofluorescence and immunoperoxidase staining. differential expression of class ii antigens was seen in chronic gingivitis in adults, with t6(+) dr(+) cells being more numerous than t6(+) dq(+) cells. the periodontopathic organism fusobacterium nucleatum (fn) induced dq expression on langerhans' cells (lc) during in vitro explant culture of gingival tissue. this effect was mimicked by endotoxin ( ...	1987	2435875
humoral antibody response against bacteroides gingivalis-specific antigen recognized by monoclonal antibody in adult periodontal patients.	an antigen recognized by monoclonal antibody specific for bacteroides gingivalis was purified in the presence of 0.5% (wt/vol) beta-octyl-glucoside by immunoadsorbent column chromatography. the purified antigen was homogeneous as judged by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) and silver staining, and the pattern of sds-page agreed with that of immunoblotting. the molecule exhibited an apparent molecular weight of about 62,000 by sds-page. the antigen was sensitive ...	1986	2426200
[malaria prevention. chemotherapy and immune prophylaxis. 3. immune response of infected organism. perspectives of malaria prevention].		1986	2423092
target size of ca-pumps in pig coronary artery smooth muscle.	the target sizes of the oxalate-independent ca uptake by the plasma membrane enriched fraction f2, and the oxalate-stimulated ca uptake by a fraction f3 slightly enriched in the endoplasmic reticulum were determined by radiation inactivation. the oxalate-independent ca uptake was inactivated with a d37 value of 1.96 +/- 0.30 mrad but the oxalate-stimulated ca uptake had a d37 value of 0.45 +/- 0.07 mrad. thus, in the smooth muscle the oxalate-stimulated ca uptake appeared to be due to a structur ...	1985	2415797
specificity of monoclonal antibodies reactive with fusobacterium nucleatum: effect of formalin fixation.	monoclonal antibody specific for fusobacterium nucleatum was reacted with untreated and formalin fixed f. nucleatum cells by an enzyme-linked immunosorbent assay (elisa) and by indirect immunofluorescence. treatment of bacterial cells with formalin destroyed the antigenic determinant responsible for reactivity with this monoclonal antibody in both assays. formalin fixation had no effect on hemagglutination activity (ha) of f. nucleatum cells or reactivity with polyvalent rabbit antiserum in doub ...	1985	2415637
modulation of hla-dr antigens in the gingival epithelium in vitro by heat-killed fusobacterium nucleatum and e. coli lipopolysaccharide.	the in vitro influence of the periodontopathic organism fusobacterium nucleatum (fn) on gingival tissue was examined using an organ culture system. treatment of gingival explants obtained from periodontally diseased sites with suspensions of fn, stimulated the expression of hla-dr antigens by langerhans cells (lc) in a dose-dependent fashion, and produced a maintenance of the lc markers t6 and atpase. similar effects were seen when e. coli lipopolysaccharide (lps) was substituted for suspensions ...	1985	2414424
resistance to beta-lactam antibiotics in anaerobic bacteria.	the known mechanisms of beta-lactam resistance in anaerobic bacteria involve production of beta-lactamases, alteration of penicillin-binding proteins, and blocked penetration of beta-lactam antibiotics through bacterial outer membranes. the most important factor in beta-lactam resistance is production of beta-lactamases, which have been found in various bacteroides, fusobacterium, and clostridium species. beta-lactam resistance in bacteroides fragilis is commonly mediated by beta-lactamases that ...	1990	2406875
health care in the united states. our dynamic jigsaw puzzle.		2008	2405797
risk factors for kaposi's sarcoma in the vancouver lymphadenopathy-aids study.	in our ongoing cohort study of homosexual men, the ratio of new kaposi's sarcoma (ks) cases to new opportunistic infections (oi) during the periods 1982-1985, 1986-1987, and 1988-1989 fell from 0.75 (9 ks: 12 oi) to 0.57 (12 ks:21 oi) to 0.27 (4 ks:15 oi), respectively. to examine factors associated with the development of ks as compared to oi, we compared antecedent risk factors in 25 ks cases and 48 oi "controls." in univariate analyses, several classical hiv risk factors including numbers of ...	1990	2395081
preliminary studies on melatonin in the treatment of myelodysplastic syndromes following cancer chemotherapy.	experimental studies have suggested that the pineal hormone melatonin, in addition to its documented antineoplastic action, plays a role in the physiological regulation of blood cell proliferation. based on these data, we evaluated the clinical effects of melatonin therapy in patients with myelodysplastic syndrome (mds) secondary to cancer chemotherapy for primary neoplasms. the study was carried out on six patients, and melatonin was given orally at a dose of 20 mg/daily, following a schedule p ...	2008	2395074
is honesty the best policy?		2007	2391008
they need more exercise.		2006	2376809
[radical surgical intervention with conventional radiation versus multimodality therapy protocol in undifferentiated thyroid cancer].	out of a total of 550 patients with thyroid cancer diagnosed over the 16-year period 1972-june 1989, 44 showed undifferentiated carcinoma and were treated by thyreoidectomy and early postoperative external irradiation. in order to analyse the outcome in patients treated by primary surgery in contrast to patients treated by means of a multimodal therapy concept we compared our surgical procedures with regard to primary surgical approach, early postoperative course, operative complications and sur ...	2008	2375117
blastogenesis and polyclonal immunoglobulin synthesis in murine spleen cells stimulated with lipopolysaccharide, lipid a and acid-degraded polysaccharide from fusobacterium nucleatum.	lipopolysaccharide of fusobacterium nucleatum strain fevl was split by acid hydrolysis. the split products, i.e. lipid a and degraded polysaccharide were mitogenic for murine spleen cells as measured by uptake of [3h]thymidine. the uptake of [3h]thymidine was dose-dependent. incubation of spleen cells with stimulants for 3 days resulted in a polyclonal activation of immunoglobulin synthesis. higher mitogenic response and immunoglobulin production were found in spleen cells of athymic mice compar ...	1990	2369526
falls and hip fracture in hong kong chinese.	the risk factors for hip fracture were studied in four hundred patients and eight hundred community and hospital controls. falling was found to be important as a direct cause of fracture. a history of falls was a significant risk factor for hip fracture in men and women younger than 70, but was less important in older men and women. medical conditions and treatments did not occur more frequently in hip fracture patients with a history of falls than in patients without, and the patients with a hi ...	2008	2359827
neurocristopathy syndrome: review of four cases.	aberrant embryologic development of the neural crest may clinically result in one of several patterns of malformation. four examples of the neurocristopathy syndrome are described that collectively feature a very broad range of expression in these infants. because of the many expressions, the syndrome may not be recognized. we believe that greater familiarity with the disorder will aid in the discovery of unsuspected anomalies and provide clues about predisposing etiologies.	2008	2359735
growth conditions and outer membrane proteins of fusobacterium nucleatum.	fusobacterium nucleatum strains atcc 10953, atcc 25586, f1 f3, f6, and fev1 were grown in different media. the influence of growth conditions on the outer membrane proteins (omps) was analyzed by sodium dodecyl sulfate--polyacrylamide gel electrophoresis (sds-page). there were no apparent differences in the outer membrane protein profiles when cells in the same phase of growth in various rich media were compared. differences, however, were observed between early logarithmic phase and stationary ...	1990	2349450
multiple periodontal abscesses after systemic antibiotic therapy.	multiple periodontal abscesses were reported in medically compromised patients. we examined patients with a non-contributory medical history referred for the treatment of numerous periodontal abscesses. all patients had taken oral broad spectrum antibiotics 1 to 3 weeks prior to the outburst of the abscesses (8 patients: penicillin, 2 patients: tetracycline). the patients suffered from advanced periodontal disease, 82% of the examined sites showed probing depths greater than 3 mm, 56% attachment ...	1990	2347952
inhibitory effects of neuropeptide y on adenylate cyclase of rabbit ciliary processes.	the inhibitory effect of neuropeptide y (npy) was studied on the adenylate cyclase (ac) activity in homogenates of rabbit ciliary processes and compared with that of the alpha 2-adrenergic agonist clonidine (cln). npy inhibited basal ac activity as well as ac activity stimulated by isoproterenol (iso), vasoactive intestinal polypeptide (vip) or forskolin (fsk). the extent of this inhibition corresponded well to the inhibition elicited by cln. the inhibitory effects of npy and cln appeared to be ...	1990	2335109
screening adolescents for depression and parent-teenager conflict in an ambulatory medical setting: a preliminary investigation.	because more than 60% of adolescent visits to physicians last less than 10 minutes, simple screening devices to identify persons at risk for social morbidity are needed. the result of a pilot screening instrument for depression and parent-teenager conflict is described. a seven-item questionnaire (three items for depression and four items for parent-teenager conflict), the beck depression inventory (bdi), and the conflict behavior questionnaire (cbq), were administered to 226 adolescents at a hi ...	2008	2330245
any value for desmopressin acetate (ddavp) in cardiopulmonary bypass operation?		2008	2329836
genetic basis of tetracycline resistance in urogenital bacteria.	the distributions of the nucleotide sequences related to the tetracycline resistance determinants tet k, tet l, tet m, and tet o were studied by dot blot hybridization with randomly chosen clinical urogenital tract isolates of viridans group streptococci, streptococcus agalactiae, enterococcus faecalis, gardnerella vaginalis, lactobacillus spp., fusobacterium nucleatum, peptostreptococcus spp., and veillonella parvula. among the peptostreptococcus spp., 79% of the isolates hybridized with one (6 ...	1990	2327774
[intraosseous administration of thymalin in the combined treatment of children with acute odontogenic osteomyelitis].	experience gained in the treatment of 63 children has demonstrated the validity of bone perforation and intraosteal drug lavage in a complex of therapeutic measures for acute mandibular odontogenic osteomyelitis running an unfavorable course. incorporation of immunostimulant thymalin in the solutions used for intraosteal lavage of the inflammation focus in this condition is conducive to normalization of the cellular and humoral immunity and liquidation of the pathologic process without destructi ...	1999	2326818
susceptibility and resistance of plaque bacteria to minocycline.	the in vitro susceptibility of 55 strains of subgingival plaque bacteria to minocycline was determined. a concentration of 1 microgram/ml minocycline was found to inhibit 85% of the strains tested and the mic ranged from 0.03 to 32 micrograms/ml. for 71% of the strains tested the mbc was at least 4 times greater than the corresponding mic, suggesting a bacteriostatic activity for minocycline. a concentration of 20 mg/ml of magnesium ions was capable of neutralizing 8 micrograms/ml of minocycline ...	1990	2324922
phytochrome from the green alga mesotaenium caldariorum. purification and preliminary characterization.	a method to purify the phytochrome photoreceptor from the unicellular green alga mesotaenium caldariorum is presented. preparative scale formation of algal protoplasts and controlled osmotic cell lysis have permitted separation of intact organelles from the phytochrome-enriched soluble protein fraction. we have utilized the observation that red light-absorbing (pr) and far-red light-absorbing (pfr) forms of phytochrome are differentially retained on an anion exchange matrix to purify m. caldario ...	2008	2324111
long-term clearance of inhaled uo2 particles from the pulmonary region of the rat.	this paper reports on an enriched uranium dioxide (uo2) mass clearance study undertaken with fischer-344 rats. the uo2 had a uranium (u) isotopic composition of 0.79% 234u, 92.8% 235u, 0.34% 236u and 6.06% 238u, by mass, with an alpha-particle activity of 1.91 bq micrograms-1. forty-six rats were exposed to an enriched uo2 aerosol that had an activity median particle aerodynamic diameter ranging from 2.7 to 3.2 microns. the rats were killed from 1 to 720 d post-inhalation (pi). the mass of enric ...	1990	2323929
diisopropylfluorophosphate-binding proteins in the outer membrane of fusobacterium nucleatum: strain variations.	six strains of fusobacterium nucleatum were tested for their ability to react with [3h]diisopropylfluorophosphate (dfp), a serine protease inhibitor. several cytoplasmic proteins were labelled but the strongest labelling was regularly observed in a few outer membrane proteins. the number and the molecular mass of the proteins detected varied according to the strain tested. a 61 kda protein was labelled in all strains tested, including the two type strains atcc 10953 and atcc 25586. a 65 kda prot ...	1990	2323539
growth stimulation of treponema denticola by periodontal microorganisms.	previous experiments have indicated that enrichment of subgingival plaque in human serum can lead to the accumulation of treponema denticola. t. denticola depends on bacterial interactions for its growth in serum. aim of the present study was to identify specific microorganisms involved in the growth stimulation of t. denticola. to this end, strains isolated from previous plaque enrichment cultures were tested for growth stimulation in co-cultures with t. denticola. in addition, growth of t. den ...	1990	2321929
species-specific oligodeoxynucleotide probes for the identification of periodontal bacteria.	oligodeoxynucleotide probes were developed for identification of the periodontal bacteria actinobacillus actinomycetemcomitans, bacteroides gingivalis, b. intermedius types i and ii, b. forsythus, eikenella corrodens, fusobacterium nucleatum, haemophilus aphrophilus, streptococcus intermedius, and wolinella recta. probes were designed by sequencing the 16s rrna for each bacterium, identifying hypervariable regions, and chemically synthesizing species-specific probes. these probes were specific w ...	1990	2312676
capnophilic and anaerobic bacteremia in neutropenic patients: an oral source.	the currently accepted empiric antibiotic therapy for bacterial infections in neutropenic patients may not cover the possibility of capnophilic and anaerobic bacteremia. many of these infections develop in patients with severe mucositis or periodontitis, and the type of organisms recovered also suggests an oral source of infection. we present two cases of bacteremia in neutropenic patients who had been empirically treated with ceftazidime and piperacillin plus amikacin. in the first case a beta- ...	1990	2305182
microbial patterns in pooled subgingival plaque samples from young adults with advanced marginal periodontitis.	different bacterial profiles of subgingival plaque have been described for different clinical categories of marginal periodontitis. in the present investigation the subgingival microflora was studied in young adults with advanced marginal periodontitis. from 12 patients pooled subgingival plaque samples from 5 advanced stages of diseased sites were examined by direct differential phase-contrast microscopy and by cultivation on enriched and selective media. the proportions of the following genera ...	1990	2293348
determination of retinol, alpha-tocopherol, and beta-carotene in serum by liquid chromatography.		2008	2292933
grading white matter lesions on ct and mri: a simple scale.	we developed and tested a simple three-point scale for grading white matter lesions in anterior and posterior regions of the brain. twenty four ct scans and 24 mri scans were separately judged by 11 and five observers, respectively, on the presence and severity of white matter lesions. the observers were radiologists and neurologists. for ct scans, these periventricular changes were graded according to their extent as absent, or partly involving the white matter, or extending up to the subcortic ...	2008	2292703
current therapy of ischaemic stroke.		2008	2292554
design, properties, and effective use of the oral chelator l1 and other alpha-ketohydroxypyridines in the treatment of transfusional iron overload in thalassemia.		2008	2291562
increased formation of dna adducts in cultured fibroblasts of patients with aplastic anemia after in vitro incubation with benzo(a)pyrene.	in inbred mice strain dba/2, genetically controlled differences in aryl hydrocarbon hydroxylase (ahh) activity have been demonstrated that predispose to aplastic anemia. to test the hypothesis of a similar mechanism in humans, we studied the formation of benzo(a)pyrene dna adducts and water-soluble metabolites in skin fibroblasts from eight patients with aplastic anemia and eight normal controls. the ratio of water-soluble metabolites and dna adducts was 46.5 +/- 16.6 in patients and was signifi ...	2008	2289825
associations between six dna probe-detected periodontal bacteria and alveolar bone loss and other clinical signs of periodontitis.	the purpose of the present study was to assess the associations between the presence and amounts of actinobacillus actinomycetemcomitans, bacteroides gingivalis, b. intermedius, eikenella corrodens, wolinella recta, and fusobacterium nucleatum in the periodontal pocket and the degree of alveolar bone loss and other clinical signs of periodonitis, such as probing pocket depth, attachment level, and presence of bleeding on probing at the same site. the study material comprised 16 subjects with or ...	1990	2288212
coaggregation of oral candida isolates with bacteria from bone marrow transplant recipients.	in vitro coaggregation between candida species isolated from immunosuppressed bone marrow transplant recipients and oral bacteria was investigated. each candida strain showed a different pattern of coaggregation with the 22 bacterial strains studied. two strains of lactobacillus amylovorus isolated from separate bone marrow transplant patients and fusobacterium nucleatum (vpi 10197) coaggregated with all candida strains. ten bacterial strains showed no coaggregation with the candida strains. a v ...	1990	2279992
lysocardiolipin formation and reacylation in isolated rat liver mitochondria.	liver mitochondrial cardiolipin (cl) is distinguished from other phospholipids by the presence of linoleoyl in almost all molecular species, and the biosynthesis of these species is not yet understood. the present study was carried out in order to test the hypothesis that the linoleoyl proportion of cl may be specifically enriched by a deacylation-reacylation cycle. incorporation of [14c]glycerol 3-phosphate into the metabolites of the cl pathway was accompanied by formation of 14c-labelled mono ...	1990	2268287
[neuro-emotional stress of work at a factory].		2008	2262147
[foreign bodies of the digestive tract].		2008	2259119
[foreign bodies of the digestive tract].		2008	2259119
specific amplification of rearranged immunoglobulin variable region genes from mouse hybridoma cells.	in this article we show how the polymerase chain reaction (pcr) and primers designed for conserved sequences of leader (l), framework one (fr1) and constant (const) regions of immunoglobulin light and heavy chain genes can be used for the cloning and sequencing of rearranged antibody variable regions from mouse hybridoma cells. rna was extracted from the mouse hybridoma cells secreting mabs: ior-t3a (anti-cd3), c6 (anti-p1 of n. meningitidis b385), ior-t1 (anti-cd6), cb-cea.1 (anti-carcinoembryo ...	1990	2258182
[bcl-2 gene involved in t(14;18) translocation].		1990	2255071
acute guillain-barré syndrome.		1989	2249465
the biotin-dependent sodium ion pump glutaconyl-coa decarboxylase from fusobacterium nucleatum (subsp. nucleatum). comparison with the glutaconyl-coa decarboxylases from gram-positive bacteria.	membrane preparations of fusobacterium nucleatum grown on glutamate contain glutaconyl-coa decarboxylase at a high specific activity (13.8 nkat/mg protein). the enzyme was solubilized with 2% triton x-100 in 0.5 m nacl and purified 63-fold to a specific activity of 870 nkat/mg by affinity chromatography on monomeric avidin-sepharose. the activity of the decarboxylase was strictly dependent on na+ (km = 3 mm) and was stimulated up to 3-fold by phospholipids. the glutaconyl-coa decarboxylases from ...	1990	2244788
cocaine-induced stroke: first jamaican case.		2007	2243239
two cytochrome p-450 isoforms catalysing o-de-ethylation of ethoxycoumarin and ethoxyresorufin in higher plants.	the o-dealkylating activities of 7-ethoxycoumarin o-de-ethylase (ecod) and 7-ethoxyresorufin o-de-ethylase (erod) have been fluorimetrically detected in microsomes prepared from manganese-induced jerusalem artichoke tubers. cytochrome p-450 dependence of the reactions was demonstrated by light-reversed co inhibition, nadph-dependence, nadh-nadph synergism and by use of specific inhibitors: antibodies to nadph-cytochrome p-450 reductase, mechanism-based inactivators and tetcyclasis. apparent km v ...	2008	2241905
[effect of enalapril on heart rate, arterial blood pressure and exocrine pancreatic secretion in the alert dog].	a changed exocrine pancreatic secretion could be a pathogenetic factor of an acute pancreatitis after administration of angiotensin-converting enzyme (ace) inhibitors. in six conscious dogs with gastric and duodenal thomas fistulas we studied the effect of an intravenous (iv.) bolus injection of 10 mg enalaprilat, an intraduodenal (id.) bolus injection of 20 and 40 mg enalapril (e.), and 0.15 m nacl (20 ml iv., resp., id.) on pancreatic bicarbonate- and protein output in response to secretin (20 ...	1990	2238764
trade and generic names of drugs.		2007	2234623
on the treatment of enchondroma.	we recommend simply removing an enchondroma without filling the cavity with cancellous bone or plaster-of-paris. this method can also be applied to other benign bone conditions, such as aseptic necrosis.	2007	2230499
stimulation of serotonin2 receptors in the ventrolateral medulla of the cat results in nonuniform increases in sympathetic outflow.	topical application of the serotonin2 agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane or doi, in a dose of 30 micrograms/side to the intermediate area of the ventrolateral surface of the medulla produced a significant increase in mean arterial pressure with no significant change in heart rate both in intact animals (n = 8) and in cervically vagotomized animals (n = 3). the pressor response of doi was blocked by pretreatment of the intermediate area with ketanserin, a serotonin2 antagonist ...	1990	2225358
cognitive and affective disorders in elderly diabetics.	in non-insulin-dependent diabetes mellitus, performance of complex cognitive tasks requiring the storage and retrieval of new information is poorer than in age-matched controls. by contrast, performance of less demanding tasks such as immediate memory and simple reaction time is essentially equivalent for niddm patients and controls. this pattern parallels the cognitive change observed with normal aging, in which age differences are minimal on less demanding immediate memory tasks but older adul ...	2007	2224744