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calcium uptake and atpase activity of microsomes from heterotopically transplanted rabbit heart.heterotopic cardiac transplantation was performed in rabbits. the calcium uptake and atpase activities of microsomal fraction were studied in three groups (group i, normal controls; group ii, early transplants; group iii, late transplants) during severe rejection as characterized histologically and electrocardiographically. group iii showed a significant decrease in calcium uptake but no difference in atpase activity compared with groups i or ii. the results demonstrate that in the rejecting tra ...1975127353
biologic activity of soluble collagen-anticollagen immune complexes as demonstrated by passive cutaneous anaphylaxis.collagen-anticollagen immune complexes were prepared by gel filtration. complex formation was chemically and serologically demonstrated. complexes eluting in gammam- and gammag-peaks of antigen-antiserum mixture showed strong positive reactions in pca experiments performed with 20 guinea pigs. control preparations of gammam- and gammag-peaks of antiserum devoid of antigen gave significantly lower pca-response. the positive reaction of control preparations can be explained in part by a certain de ...1975127469
histoenzymatic changes in liver in acute poisoning with furfural. 1975127937
cell number in human heart in atrophy, hypertrophy, and under the influence of cytostatics.the dna content was determined in 30 human hearts from different age groups and of different weight classes. among these cases were included 4 hearts of children and 5 hearts of adults who had been treated with cytostatics. the total dna content was determined biochemically and the nuclear dna content was measured by means of feulgen cytophotometry. by combining both methods, the total number of heart muscle cells was determined. we obtained the following results: (1) the dna concentration remai ...1975128080
total viable count and differential count of vibrio (campylobacter) sputorum, fusobacterium nucleatum, selenomonas sputigena, bacteroides ochraceus and veillonella in the inflamed and non inflamed human gingival crevice. 1975129552
survival of anaerobic and aerobic bacteria on cotton swabs in three transport systems.the capacity of aerobic and anaerobic bacteria to survive on cotton swabs placed into a dry gassed-out co2-filled tube (dgt), dry sterile aerobic tube (dat), and a tube containing a modified stuarts' transport medium (mst), was assessed. pseudomonas aeruginosa increased in numbers by 2 and 3 logs when stored in mst and dat, respectively. the viability of p. aeruginosa, although retarded when compared to msa and dat, was not adversely affected by the co2 environment in the dgt. the mst maintaine ...1975240870
a modified plate holding system for anaerobic cultures.a modified plate holding system for anaerobes has been developed which: 1) effectively reduces the volume of oxygen-free gas required, 2) promotes earlier bacterial growth, and 3) monitors the anaerobic atmosphere of the holding vessel and the rate of gas flow. cultures of bacteroides fragilis, clostridium perfringens, c. septicum, fusobacterium nucleatum, peptococcus sp. and propionibacterium sp. were evaluated for optimal growth. all cultures grew as well as or better when preincubated in the ...1976782243
effect of sonic treatment on pure cultures and aggregates of bacteria.pure cultures of a variety of bacteria were treated with ultrasonic energy using a sonic probe. fractions of organisms killed at different sonic energies were calculated, and streptococcus mutans was 600 times more resistant than fusobacterium nucleatum, the most sensitive organism tested. the effects of sonic treatment on aggregates of bacteria were examined, and the results were interpreted as a model of the events that probably occur during the sonic dispersion of dental plaque.1976819454
dynamics of sulfonylurea-induced insulin release from the isolated perfused rat pancreas.in the isolated perfused rat pancreas various sulfonylurea drugs were tested with a basal glucose level of 1 mg/ml in the perfusion buffer and were found to cause a biphasic insulin response. novocs 476, a new and potent sulfonylurea, and glibenclamide qualitatively differed from tolbutamide, glibornuride, glipizide, and glisoxepide, which were all alike in terms of the relationship between first and second phases of insulin release.1976134920
the detection of antibodies in human and animal filariases by counterimmunoelectrophoresis with dirofilaria immitis antigens.counterimmunoelectrophoresis revealed the presence of precipitin antibody in all of 6 dogs and the 1 cat infected with dirofilaria immitis and in the serum of 17 of 24 individuals living in a setting of hyperendemic subperiodic bancroftian filariasis. antigens used in the test were prepared from microfilariae and adult male d. immitis. some humans and animals had antibodies to both antigens while others had antibodies against microfilariae or adult worms only. the presence of soluble circulating ...19761262695
attenuated, streptomycin-dependent salmonella typhi oral vaccine: potential deleterious effects of lyophilization.four studies were done with streptomycin-dependent salmonella typhi as an oral, attenuated vaccine. studies 1 and 3 employed freshly harvested vaccine, whereas studies 2 and 4 involved lyophilized vaccine. five to eight doses (3 x 10(10)-10(11) organisms/dose) were given; oral streptomycin (1.0 g) was administered concomitantly in studies 2 and 3, with only two of the doses of vaccine in study 1, and was not given in study 4. no adverse reactions were encountered in 179 vaccinated men, and 94% o ...19761262709
hyperbaric oxygen exposures for intrahepatic abscesses produced in mice by nonsporeforming anaerobic bacteria.hyperbaric oxygen exposures were evaluated for treatment of progressive liver abscesses produced by intraperitoneal injection of combined cultures of fusobacterium necrophorum plus either bacteroides fragilis subsp. fragilis or fusobacterium nucleatum in a mouse model. infected control and hyperbaric oxygen-exposed mice were autopsied 5 or 6 weeks after inoculation of bacteria and were assigned numerical pathology scores according to the number and size of abscesses present. seventeen daily 3-h ...19761267430
rosamicin: in vitro activity against anaerobes and comparison with erythromycin.the in vitro activity of rosamicin was determined against 231 strains of anaerobic bacteria and compared with the activity of erythromycin against the same strains. rosamicin and erythromycin had similar activity against strains of peptostreptococcus and gram-positive nonsporeforming bacilli. rosamicin was somewhat more active against strains of peptococcus, clostridium, and gram-negative anaerobes. all strains of bacteroides fragilis tested were inhibited by 4 mug of rosamicin or less per ml, w ...19761267432
[test of degranulation of basophils and mast cells for detection of allergic diseases (literature survey)]. 19761274295
absolute configuration of 3-hydroxy fatty acids present in lipopolysaccharides from various bacterial groups.the absolute configuration of 3-hydroxy fatty acids has been studied, which are present in the lipopolysaccharides of the following bacteria: phodopseudomonas gelatinosa, rh. viridis, rhodospirillum tenue, chromobacterium violaceum, pseudomonas aeruginosa, bordetella pertussis, vibrio metchnikovii, vibrio cholerae, salmonella spp., escherichia coli, shigella flexneri, proteus mirabilis, yersinia enterocolitica and fusobacterium nucleatum. the 3-hydroxy acids were liberated by strong alkaline hyd ...19761278168
genital herpetic infection in men and women: clinical course and effect of topical application of adenine arabinoside.sixty-three episodes of genital herpetic infection in 55 men and 45 episodes in 42 women were randomly assigned to topical treatment with 3% adenine arabinoside, topical treatment with placebo ointment, or no therapy. in addition, 10 episodes in women who were not randomly assigned to therapy were evaluated and followed. clinical evaluation and viral cultures were done on day 3, day 8, and weekly thereafter until the lesions had healed. the natural clinical course of genital herpetic infection w ...1976180196
effectiveness of orally administered bordetella pertussis vaccine in mice.oral administration of killed bordetella pertussis organisms to mice results in increased resistance to an intracerebral infection with virulent b. pertussis cells. the rate of survival is dependent on the dose of antigen. but besides specific systemic immunity, which is persistent over a long period, also transient non-specific resistance is increased. these effects are evidently induced without penetration of bacterial substances into the circulation.1976182602
inflammatory cells in solid murine neoplasms. i. tumor disaggregation and identification of constituent inflammatory cells.mechanical and enzymatic methods of disaggregating tumors were studied with the goals of (1) minimizing cell losses while (2) maintaining functional and surface membrane markers needed to objectively identify inflammatory cells (ic)1 in resultant suspensions. application of the principles and methods described makes accurate estimation of the percentage of each ic type present in neoplasms possible for the first time. compared to purely mechanical means of disaggregating tumors, all enzyme mixtu ...1976182647
the effect of hypoxia on collagen synthesis in cultured 3t6 fibroblasts and its relationship to the mode of action of ascorbate.when exposed to low oxygen tension, in the absence of added ascorbic acid 3t6 mouse fibroblast cultures in late log phase respond by increased lactate production and increased hydroxylation of proline in nascent collagen, which is paralleled by an increase in prolyl hydroxylase activity. after 6 h recovery from the anoxic stimulus, however, cultures still yield more prolyl hydroxylase than controls, but the effect on hydroxylation of nascent collagen has disappeared. these observations help to d ...1976183826
study of the properties of different strains of avian encephalomyelitis virus. 1976187531
polymorphism of human color vision.the genetic polymorphism of human color vision is examined within the framework of a photopigment replacement model. an analysis of the x-linked recessive dichromacies and anomalous trichromacies indicates that one source of variability of normal color perception may be the inclusion of several distinct phenotypes in what is usually described as normal color vision. this analysis also reveals the cause of the dominance hierarchy at the protan and deutan loci, the perceptual effects of dosage com ...19761087832
effect of repeated bloodletting on the incidence of 2,7-faa-induced rat leukemia.the oral administration of n,n'-2,7-fuorenylenebisacetamide (2,7-faa) induced leukemia, especially mature granulocytic leukemia, in rats. 2,7-faa was administered to the rats of the wistar strain and a small amount of bloodletting was repeated for a long period. the incidence of leukemia and mature granulocytic leukemia became elevated by bloodletting. the induction of mature granulocytic leukemia might be increased by the promotion of granulopoiesis which had been suppressed by 2,7-faa.19761068628
in vivo metabolism of progestins. v. the effect of protocol design on the estimated metabolic clearance rate and volume of distribution of medroxyprogesterone acetate in women.the metabolism of the synthetic progestin, [3h]medroxyprogesterone acetate (mpa), was studied in women using a single injection technique. computer-implemented analysis was used to calculate the mcr (mcrmpa) and volume of distribution (vompa) from the steroid disappearance curve. the value of an objective curve-fitting technique was demonstrated. the effect of protocol design (number and frequency of samples) on these metabolic parameters was evaluated. the estimation of vompa was most sensitive ...1976429526
studies comparing the metabolic clearance rate of 11 beta,17,21-trihydroxypregn-1,4-diene-3,20-dione (prednisolone) after oral 17,21-dihydroxypregn-1,4-diene-3,11,20-trione and intravenous prednisolone.the mcr of prednisolone (11 beta,17,21-trihydroxypregn-1,4-diene-3,20-dione) and the absorption of prednisone (17,21-dihydroxypregn 1,4-diene-3,11,20-trione) were studied in five normal subjects and four patients. plasma and urinary prednisolone were measured by a competitive radioassay. the mcr was determined after iv administration of 30 mg nonisotopic prednisolone using one-compartment (mcr1) and two-compartment (mcr2) analyses. these values were compared with the mcr determined after oral ad ...1976429520
accreditation: team surveys provide greater depth. 1977234887
regulation of norepinephrine release from cardiac sympathetic fibers in the dog by presynaptic alpha- and beta-receptors.the effect of phenoxybenzamine (pba), desmethylimipramine (dmi), clonidine (clnd), sotalol (stl), and isoproterenol (ispr) on the release of endogenous norepinephrine (ne) from the heart on right cardioaccelerator nerve stimulation was studied in anesthetized dogs. under control conditions, the catecholamine levels in coronary sinus blood increased linearly with increasing frequencies of stimulation up to 10 hz and did not increase further at 30 hz. the release of ne was markedly enhanced after ...1977193655
adenovirus of ring-necked pheasants: purification and partial characterization of marble spleen disease virus.a method for purification of marble spleen disease virus (msdv) from the spleens of infected turkeys and pheasants is described. it combines chloroform or fluorocarbon extraction with subsequent purification by centrifugation on a cushion of cesium chloride (cscl). further purification of msdv was accomplished with a cscl equilibrium density gradient. a viral buoyant density of approximately 1.32 to 1.33 g/cm3 was determined. negative-stain electron microscopy revealed that virus isopycnically b ...1977193796
on the mode of action of clonidine: relationship between effects on behaviour and cyclic nucleotide content in mouse brain. 1977196226
quantitative electron microscopic studies of the changes in rat hepatocytes following halothane induced anaesthesia. 197798410
[the antibacterial action on dental plaque of antibiotics used in dentistry. 2. in vitro experiments on streptococcus mutans, staphylococcus aureus and fusobacterium nucleatum (author's transl)]. 197788239
effect of oophorectomy on estrogen receptors in rat mammary tumors induced by 7,12-dimethylbenz (a)anthracene. 197796813
the metabolic effects and uptake of ethidium bromide by rat liver mitochondria. 1977141908
biochemical and morphological studies of rat submandibular gland: iii. effects of testosterone treatment on proteins of granule-rickch fraction.mature adult male rats and castrated and testosterone-treated castrated adult rats were injected with pilocarpine hcl and 3-h-lysine and sacrificed sequentially over an eight-hour time period. following homogenization and differential centrifugation, three subcellular fractions from each group of animals were analyzed by gel electrophoresis and liquid scintillation. two proteins in the granule-rich fraction appeared in larger amounts on the densitometric scans and appeared to represent a larger ...1977265956
[actinomyces in dental plaque]. 1977266558
the predominant cultivable microflora of advanced periodontitis.a study on the predominant cultivable microorganisms harbored in the base of deep periodontal pockets of eight patients aged 34-48 years was carried out using the roll tube culture technique. from a total of 475 isolates, 425 (89.5%) were obligate anaerobes, 356(74.9%) were gram-negative, and 441(92.8%) were categorized as rods. bacteroides melaninogenicus and fusobacterium nucleatum constituted the majority of the isolates in seven samples, but their mutual proportions differed considerably bet ...1977320648
inhibition of leukocyte migration by the agarose plate technique. application to antigen from candida albicans and fusobacterium nucleatum.leukocyte migration inhibition by antigen from candida albicans and fusobacterium nucleatum was studied in man by means of the direct leukocyte migration agarose technique (lmat). antigens were prepared by prolonged ultrasonication and were added to the leukocyte cultures in the original as well as in the concentrated solutions. significant inhibition of migration with a 10-fold concentrated solution of candida antigen was demonstrated in subjects showing apositive intracutaneous reaction to can ...1977320806
escape from antibody-mediated immune suppression in vitro by delayed-type hypersensitivity reaction.anti-sheep erythrocyte antiserum suppressed the in vitro immune response of swine spleen cells to sheep erythrocytes. inhibition of the in vitro anti-sheep erythrocyte response was also observed in neonatal spleen cells, which were obtained from piglets recently fed colostrum. addition of purified protein derivative (ppd) to spleen cell cultures prepared from animals previously sensitized to mycobacterium bovis reversed the immunosuppression caused by passive antibody. passive antibody regulatio ...1977321357
the germicidal effect of the open air in different parts of the netherlands.using the microthread technique the survival of escherichia coli mre 162 in open air was measured in different parts of the netherlands. the presence of bactericidal compounds (open air factor = oaf) could be demonstrated on several days and quantitated in relative units of oaf concentration. in the absence of ozone the oaf concentration was always low. in the presence of ozone the oaf concentration was dependent on wind direction. at the selected microthread exposure sites air from areas with h ...1977321676
gliding motility and actinomycin d sensitivity of fusobacterium nucleatum and other gram-negative rods.six strains of gram-negative anaerobic fusiform rods (fusobacterium and bacteroides spp.), isolated from deep subgingival locations in humans, were examined for (i) gliding motility in slide cultures, (iii) cell densities on nutrient agar surfaces, and (iii) sensitivity to actinomycin d. known gliding (fbt) and nonmotile (nm) strains of myxococcus xanthus served as controls for the gliding and cell density experiments. in the present study, three strains of gram-negative fusiforms from the oral ...1977332633
chemical structure of the lipid a component of lipopolysaccharides from fusobacterium nucleatum.the lipid a component of lipopolysaccharides from fusobacterium nucleatum fev 1 consists of beta-1',6-linked d-glucosamine disaccharides, which carry two phosphate groups: one in glycosidic and one in ester linkage. the amino groups of the glucosamine disaccharides are substituted by d-3-hydroxyhexadecanoic acid. the hydroxyl groups of the disaccharide backbone are acylated by tetradecanoic, hexadecanoic, and d-3-hydroxytetradecanoic acids. part of the ester-bound d-3-hydroxytetradecanoic acid i ...1977830651
[in vitro susceptibility of bacteroidaceae to cefoxitin and cephalothin (author's transl)].the activity of the new cephamycin c derivatives cefoxitin against 102 clinical isolates of bacteroidaceae (95 bacteroides strains and 7 fusobacterium-sphaerophorus cultures) was determined by tube dilution and standardized agar diffusion tests and compared to that of cephalothin. cefoxitin was more active than cephalothin against 56 bacteroides fragilis strains, 19 bacteroides thetaiota-omicron strains and two bacteroides splanchnicus strains. the difference seemed less pronounced with five bac ...1977856727
hepatic necrobacillosis. report of a case resembling metastatic tumor.a 47-year-old man had multiple pyogenic liver abscesses from which the anaerobic bacteria fusobacterium nucleatum and peptostreptococcus were isolated. the clinical course, diagnostic evaluation, and appearance of the lesions at surgery suggested metastatic tumor. histologically, the lesions consisted of necrotic liver tissue surrounded by zones of acute and chronic inflammation and fibrous connective tissue closely resembling the lesions of hepatic necrobacillosis attributable to f necrophorum. ...1977869652
lethality for mice and chick embryos, pyrogenicity in rabbits and ability to gelate lysate from amoebocytes of limulus polyphemus by lipopolysaccharides from bacteroides, fusobacterium and veillonella.phenol-water extracted lipopolysaccharides (lps) from veillonella, fusobacterium nucleatum, bacteroides fragilis and bacteroides melaninogenicus were lethal for mice and 11-days-old chick embryos, pyrogenic in rabbits, and gelated limulus amoebocyte lysate. mouse lethality was considerably enhanced by actinomycin-d. in all test systems the endotoxin activity of veillonella and fusocbacterium lps was comparable to that of lps from salmonella enteritidis, which was included as a reference endotoxi ...1977564596
susceptibility to erythromycin of anaerobes of the genera bacteroides, fusobacterium, sphaerophorus, veillonella, clostridium, corynebacterium, peptococcus, peptostreptococcus.the minimal inhibitory concentrations (mic) of erythromycin were determined by broth dilution tests for 313 anaerobic strains, most of which were clinical isolates. all the gram-positive anaerobes tested (84 peptococcaceae, including 21 peptostreptococcus anaerobius and 15 peptococcus variabilis; 65 corynebacterium acnes and 29 clostridium strains, including 13 c. perfringens) were sensitive (mic values 0.012 through 3.12 microgram erythromycin/ml); so were 111 cultures of gram-negative anaerobe ...1977580038
hemagglutinating activity of fusobacterium nucleatum.gingival isolates of oral fusobacterium nucleatum strains (gram-negative anaerobic fusiform bacilli) have shown the characteristic ability to hemagglutinate a variety of erythrocytes (rbc) of human and animal origin. other members of the genus tested (f. necrophorus, f. varium, and f. mortiferum) displayed little if any ability to hemagglutinate rbc. the hemagglutination (ha) activity could be observed in the f. nucleatum strains with the whole cells and in most instances with sonicated preparat ...1977401771
[the effect of dietary lactose on the ileal absorption of sodium taurocholate in rats].when rats were fed a lactose containing diet, both the absorption rate of sodium taurocholate at the level of ileum and the contents of bile acids of the small intestine were increased. on the contrary, feeding of lactose did not modify the daily fecal excretion of bile acids. it therefore appears that dietary lactose increases the intestinal pool of bile acids by increasing their ileal absorption rate and that this effect of lactose is not subordinated to a modification of bile acid synthesis.1977404060
thyrotrophin releasing hormone-induced growth hormone and prolactin release: physiological studies in intact rats and in hypophysectomized rats bearing an ectopic pituitary gland.to determine how the sensitivity of the ectopic anterior pituitary gland to the gh-releasing effect of thyrotrophin releasing hormone (trh) might be affected by the time lapse from transplantation, trh (0-15 and 0-6 microng) was injected i.v. into hypophysectomized (hypox)-transplanted rats under urethane anaesthesia 1,3,8,15,30 and 60 days after transplantation, and plasma samples were taken 5 and 10 min later. baseline gh values gradually decreased with time from about 16-0 ng/ml (1 day) to ab ...1977404376
effects of intravenous infusion of trh on plasma tsh and prolactin concentrations in rats. 1977404643
analysis of the shoulder in brachiating spider monkeys. 1978414626
compact liquid nitrogen storage system yielding high recoveries of gram-negative anaerobes.a simple and compact system suitable for the preservation of fragile gram negative anaerobes and other bacteria in liquid n2 has been developed. polypropylene straws used as specimen containers can be used easily within glove bags of anaerobic chambers, and their small size greatly increases the number of cultures which can be stored. ancillary equipment and methods developed are described. the overall system was tested, using streptococcus mutans, fusobacterium nucleatum, and selenomonas sputig ...1978623475
immunoelectron microscopic localization of lipopolysaccharides in the cell wall of bacteroides oralis and fusobacterium nucleatum.lipopolysaccharides (lps) have been extracted and purified from two anaerobic gram-negative bacteria: bacteroides oralis and tfusobacterium nucleatum. chemical analysis of the preparations showed a great proportion of neutral sugars, mainly glucose, in lps of b. oralis. in rabbits, lps of b. oralis induced both immunoglobulin m and g antibodies in contrast to lps of f. nucleatum, to which only immunoglobulin m antibodies were produced. an immunohistochemical method with horseradish peroxidase-la ...1978624589
[lung abscess due to fusobacterium nucleatum (author's transl)].a patient with epilepsy, 45 years of age, developed a lung abscess due to fusobacterium nucleatum which was successfully treated with intravenous lincomycin. quantitative anaerobic cultures of washed sputum proved to be useful in detecting the causative organism.1978650887
chemotypes of fusobacterium nucleatum lipopolysaccharides.lipopolysaccharides (lps) were isolated from 20 strains of fusobacterium nucleatum and examined by paper chromatography, gas liquid chromatography and colorimetric methods for the presence of neutral sugars, amino sugars and 2-keto-3-dexoxy-octonate (kdo). the lps had in common glucosamine, l-glycero-d-manno-heptose, glucose and kdo. the kdo content was low. galatose, rhamnose and d-glycero-d-manno-heptose were found in some strains. based on the sugar composition of the lps, the f. nucleatum st ...1978665242
in vitro activity of tiamulin (81.723 hfu), a new pleuromulin derivative, against clinically significant anaerobes.the susceptibility of more than 40 strains of gram-negative and gram-positive anaerobes to tiamulin (sandoz 81.723 hfu), a new pleuromulin (pleuromutilin) derivative, was determined by broth dilution and agar dilution tests. the influences of density of the inoculum upon mics was studied by a specially designed pour plate-technique. bacteroides fragilis, b. vulgatus, b. splanchnicus, b. oralis, b. asaccharolyticus, b. melaninogenicus, fusobacterium fusiforme (f. nucleatum), sphaerophorus necroph ...1978690009
the structure of the collagen fibril. 1978262321
bacillus subtilis 168 genetic transformation mediated by outgrowing spores: necessity for cell contact.transforming activity released in sequential genetic order during the first synchronous cycle of dna replication during outgrowth of spores of bacillus subtilis 168 was investigated. a transformation assay was used consisting of outgrowing spores as dna donors and multiply marked competent cells as recipients. dna synthesis inhibitors known to stop dna release were used during and subsequent to dna transfer to recipient cells. the released dna sedimented with the outgrowing cells after low-speed ...197896105
polarized light retinal photography of a monkey eye. 197896590
unsustained multiplication of treponema pallidum (nichols virulent strain) in vitro in the presence of oxygen.treponema pallidum (nichols virulent strain) was incubated with or without oxygen using a modified medium supplemented with reduced glutathione and a variety of nutrients (prnf10-b). two- to fourfold increases in treponemal numbers were observed in cultures without mammalian cells within 96 h of incubation under 5 to 6% oxygen. treponemal motility and multiplication were maintained more satisfactorily in cultures that were diluted and transferred daily, using an equal volume of fresh medium. tre ...1978344209
cell-mediated immunity in neonatal calves: delayed-type hypersensitivity and lymphocyte blastogenesis following immunization with a mycobacterial immunopotentiating glycolipid and tuberculoproteins of mycobacterium bovis. 1978347995
[endocrine function of the salivary glands].the concept of the incretory activity of the parotid and submandibular salivary glands stems from numerous clinical and experimental data indicating a close association between them, sex and pancreatic glands and the pituitary. the paper presents the data on the mechanism of action of the salivary glands hormone, parotine. the participation of the salivary glands, especially at early stages of body formation, in the processes of mineralization of bones and teeth, and in proliferation of the elas ...1978348164
nucleotide sequence of the promoter--operator region of the tryptophan operon of salmonella typhimurium. 1978351192
the bacteriology of cavitating pulmonary infections and empysema. studies of transtracheal aspirates and pleural fluid.a prospective study of bacteriology in 14 cases of cavitating pulmonary infections and empyema is reported. bacteriologic results were based on transtracheal aspirates or pleural fluid. appropriate anaerobic bacteriologic methods were employed. anaerobic bacteria were recovered in 11 patients (79%); they were the only pathogens isolated in 6 patients. the predominant species were fusobacterium nucleatum, bacteroides melaninogenicus, bacteroides fragilis and peptostreptococcus. aerobic bacteria w ...1978352421
effects of storage in an anaerobic transport system on bacteria in known polymicrobial mixtures and in clinical specimens.an anaerobic transport system (ats) which provides for catalytic removal of oxygen was evaluated by using in vitro-prepared polymicrobial mixtures of logphase bacteria and clinical specimens. inoculated swabs were stored at room temperature in (i) aerobic, (ii) anaerobic glove box, and (iii) ats environments, and bacteria were quantitated after 2, 24, 48, and 72 h. bacteria in a three-part mixture of bacteroides fragilis, peptostreptococcus anaerobius, and escherichia coli and in a five-part mix ...1978370142
binding and release of eukaryotic initiation factor eif-2 and gtp during protein synthesis initiation.the eukaryotic initiation factor eif-2 forms a ternary complex with met-trnaf and gtp. this complex binds to the 40s ribosomal subunit in the absence of mrna and mrna binding factors. highly purified eif-2 from rabbit reticulocytes was labeled with 125i by using the bolton-hunter reagent or with [gamma-32p]atp by using the heme-regulated translational inhibitor protein kinase. the labeled eif-2 was bound, together with equimolar amounts of met-trnaf and gtp, to the 40s subunit. in the presence o ...1978272635
microbiota of gingivitis in man.a study on the predominant cultivable microorganisms inhabiting gingival crevices affected with a chronic gingivitis was carried out using the roll tube culture technique. samples were obtained from nine individuals 25--42 years of age. gram-positive rods make up 29.1% of the isolates and included mainly actinomyces naeslundii, actinomyces israelii, and actinomyces viscosus. streptococcus mitis and streptococcus sanguis together made up 26.8% of the cultivable organisms. peptostreptococcus avera ...1978276916
the anticomplementary activity of lipopolysaccharide preparations and sonicates from a strain of fusobacterium nucleatum. 1978147329
experimental spongy degeneration of the white matter induced by 6-aminonicotinamide intoxication.spongy state and degeneration of the white matter in the 6-aminonicotinamide intoxicated rats were studied neuropathologically and electromicroscopically. young albino rats, four weeks of age, received 0.1% of 6-aminonicotinamide solution intraperitoneally as a single dose of 10 mg/kg of body weight. four hours after the administration, paralysis of the hind limbs occurred in the rats. neuropathological investigations revealed a characteristic spongy and degenerative change of white matter as we ...1978149717
effect of human immunoglobulin preparations on fc rosette formation between anti-d-coated erythrocytes and lymphocytes.human immunoglobulin (ig) preparations were tested for their inhibitory effect on fc rosette formation between anti-d-coated human erythrocytes and lymphocytes, as compared to their complement activating capacity. both of the two biological activities ascribed to the sites in the fc portion of the igg molecules were found to be reduced in the pepsin-treated, as well as in the s-sulfonated ig preparations, as compared to the activities of the normal human ig preparation. in the plasmin-treated ig ...1978150144
[new species of obligate-thermophilic bacteria of the flavobacterium thermophilum type]. 1978154607
[suprachiasmatic nucleus, an hypothalamic regulation center of vital rhythmic functions]. 197897067
regulation of the rate of beta-galactosidase synthese by the bgs and bgt loci in the mouse.we have developed an assay for the in vivo rate of beta-galactosidase synthesis in mouse tissues to assess the mechanism by which the bgs and bgt loci regulate activity levels of this enzyme. genetically determined differences in liver and kidney beta-galactosidase content reflect equivalent differences in specific rates of enzyme synthesis. we conclude that bgs and bgt regulate beta-galactosidase activity by controlling the rate of synthesis of the beta-galactosidase molecule.197897289
[intracellular oxygen and the radiosensitization of cells of the blue-green alaga, anacystis nidulans].the photosynthetic system of the blue-green alga anacystis nidulans was inactivated by 30% at a dose of 100 krad of gamma irradiation in n2. if the cells were irradiated in n2+2% co2 in the light, their radiation sensitivity was increased with an oxygen enhancement ratio of 2.0. neither light nor co2 taken separately affected radiosensitization of the cells which increased almost to the same extent as under aerobic conditions in the presence of both light and co2. the intracellular oxygen of the ...197897503
effect of low temperature on growth, viability, and synthesis of mycolic acids of mycobacterium tuberculosis strain h37ra.cultures of mycobacterium tuberculosis strain h37ra were grownto early logarithmic phase at 37 degrees c and were incubated at 16 degrees, 20 degrees, and 25 degrees c. the decrease in this ability was more rapid at 20 degrees c than at 16 degrees c. low-temperature incubation caused decreases in the ratios of mycolic acids and monounsaturated c16-19 fatty acids relative to the total of fatty acids synthesized. it also caused an increase in the ratio of saturated c24-26 fatty acids relative to ...197898081
trh-like immunoreactivity in urine, serum and extrahypothalamic brain: non-identity with synthetic pyroglu-hist-pro-nh2 (trh).trh-like immunoreactive substances obtained from several areas of rat brain and from human serum and urine were chromatographically separated by tlc and the resulting immunoreactive 'elution profiles' compared with that obtained for pyroglu-hist-pro-nh2 (trh). for hypothalamus and septal-preoptic samples trh was present, but represented less than 100% of the immunoreactive substances. for cortex, amygdala, brain stem, serum and urine, no trh was detectable in the immunoreactive substances from t ...197898209
[intratypical antigenic differentiation of poliovirus strains circulating in mali by means of cross-adsorbed sera].the intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in mali in 1975-1976 was performed. the method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. all the examined strains of serologic types i, ii, and iii were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". quantitative differences in the ant ...197886237
the effect of mixed phosphatidylcholine liposomes on beef heart cytochrome c oxidase [proceedings]. 197884573
acupuncture: its neurophysiological basis: an anaesthetist's foreword. 197829773
solid phase indirect radioimmunoassays for the rapid diagnosis of sindbis virus antigen.indirect radioimmunoassays have been developed for the rapid detection of sindbis virus. dilutions of sindbis virus from tissue culture fluids have been immobilized and allowed to react with rabbit anti-sindbis virus antibodies. the bound antibodies were assayed either by 125i-labelled anti-rabbit igg-antibodies or alternatively by addition of human complement and 125i-labelled anti-human c1q antibodies or 125i-labelled protein a.197884855
[post-extrasystolic and post-pacing potentiation. ii. study by means of systolic time intervals in man]. 197888948
[clinical, parasitological and serological investigations in sarcosporidiosis (sarcocystis suihominis) of man (author's transl)].eight medical students ate for a test raw meat from a pig experimentally infected with sporocysts of sarcocystis suihominis. the meat had been officially controlled before and was found free of trichinella and qualified for consumption. 6 to 24 hours after the meal all persons suffered from acute clinical symptoms, above all diarrhoea and vomiting, coldness and sweating which decreased, however, within 12 to 24 hours. clinical-chemical investigations made during this time suggested an acute infe ...197898426
freedom, the will-o'-the-wisp. 197898690
quantitation of particles in the freeze-fractured nuclear membrane after renal ischemia.changes in the number and sizes of membrane-associated particles have been quantitated in the protoplasmic (p) and exoplasmic (e) fracture faces of the outer membrane of nuclei isolated from the inner cortex following renal ischemia and reflow in the rat. no changes were observed in the inner nuclear membrane. after 20-min ischemia, the number of particles in both fracture faces decreased. with reflow, the total number of particles decreased after both 20- and 60-min ischemia. the partition coef ...197898907
[measurement of the variations of cytoplasmic and nuclear volumes of the absorbing cells of the digestive tube according to the nutritional conditions, in the larva of the common toad (bufo bufo l.)]. 197898945
jaundice and breast-feeding among alaskan eskimo newborns.the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ...197899026
[cannabis].cannabis produces a resin, the psychotropic effects of which are known since the high antiquity. it induces euphoria, a feeling of pleasant dreaminess. nevertheless, psychiatric disturbances such as psychomotor deficiency states or acute oniroïd states were described in heavy users countries. these psychiatric disorders put the accent on the starting or catalysing role of cannabis on the premorbid personality. the experimental studies of cannabis on the premorbid personality. the experimental st ...1978100034
[epidemiological study on beta hemolytic streptococci among healthy school children in toda city, saitama (author's transl)]. 1978101618
appearance of histochemically detectable ionic calcium in degenerating primary sensory neurons.the effect of neonatal capsaicin treatment on the fine structure and localization of ionic calcium in sensory ganglion cells has been investigated in rats. neonatal capsaicin treatment resulted in the degeneration of certain type b sensory neurons. at the same time ionic calcium was demonstrated histochemically in the perikarya of numerous small-sized ganglion cells. the appearance of histochemically detectable ionic calcium in these cells in relation to the pharmacologically evoked degeneration ...1978104522
[effect of polychlorinated biphenyls in the rat: ii.--preliminary report on metabolic alterations (author's transl)].rats were fed with a diet containing 10 and 100 ppm (wet weight) of phenoclor dpr for 4 weeks in order to evaluate the toxicity of a french pcb mixture. the influence of pcb was studied by determining the liver weights, the hepatic and muscular proteins, glycogen and humidity content as well as hematocrite, glucose, proteins and lipids in the plasma, and the lipidic contents of the liver and the carcass. there was a significant increase in both liver to body weight ratios and liver lipid and pro ...1978105425
comparison of interferon action in interferon resistant and sensitive l1210 cells.translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...1978212514
purification and properties of hydrogenase from clostridium pasteurianum. 1978213683
pathogenesis of infectious mononucleosis, burkitt's lymphoma and nasopharyngeal carcinoma: a unified scheme. 1978221392
comparison of immune responses and viral markers in herpesviruses-associated carcinomas: a review. 1978221405
33. the orthopedic treatment of patients with apallic syndrome. 1978414076
accountability. 1978242782
energy/protein index: iii. correlation with a biochemical parameter which reflects protein nutritional imbalance.to establish the usefulness of the energy/protein index, a study was made to assess its correlation with a biochemical parameter able to detect marginal forms of protein-energy malnutrition such as the non-essential/essential aminoacid ratio. a simple linear regression model was proposed and tested in a sample of ninety-seven malnourished children, by means of analysis of variance. the model was satisfactory. a highly significant (p less than 0.001) correlation coefficient of r = 0.552 was found ...1979414514
treatment of the incompletely formed tooth. 1979275360
[use of skin of convalescents in treatment of wounds of patients with emaciation caused by burns]. 1979327670
[autodermal plasty in 3-a stage burns]. 1979327669
[in memoriam friedrich pfeiffer, d.v.m. hannover]. 1979352662
vertebral osteomyelitis caused by fusobacterium nucleatum: a case report.a 58-year-old man with a history of chronic alcohol abuse presented with vertebral osteomyelitis caused by fusobacterium nucleatum. this case demonstrated the foul smelling abscess characteristic of anaerobic infection. deep anaerobic infections are well known to be resistant to closed treatment, and the computerized tomographic scan confirmed the diagnosis of a paravertebral abscess in this case. an increased awareness among clinicians that anaerobic bacilli can cause oteomyelitis, together wit ...197924823152
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