Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| evidence for subgroups of adextrals based on speech lateralization and cognitive patterns. | some non-right-handers may prefer the left hand by virtue of well-organized or high levels of spatial ability, vested primarily in the right hemisphere, rather than as a result of anomalous speech representation. this study tested the hypothesis that adextral (left-handed or ambidextrous) individuals with high spatial ability might have cerebral speech lateralization patterns similar to dextrals. paper-and-pencil tests of various cognitive abilities, a verbal dichotic listening task, and a hande ... | 2009 | 2771036 |
| second international symposium on new quinolones. geneva, switzerland, 25-27 august 1988. | 2009 | 2772475 | |
| [excretion of phenoltetrachlorophthalein in the bile in rats]. | phenoltetrachlorphthalein secretion into bile was followed in wistar strain rats intoxicated per os by tetrachlormethane (0.25, 0.50, 2.00, and 3.00 ml/kg) after 1, 2, 4 and 8 days after intoxication. biotransformation processes resulting in the formation of phenoltetrachlorphthalein metabolites are altered during the intoxication unequally. so far mutual relation of secreted metabolites has not been proved to serve generally as a simple criterion for absolute activity assessment of hepatic gluc ... | 1989 | 2772547 |
| [construction and testing of a strain gauge for measuring masticatory force]. | the main objective of this study was to establish and test a measuring system for monitoring occlusal forces and force cycles during mastication. a measuring module using strain gauge transducers was incorporated in the bridge-pontic of a three part test bridgework. a load cell was used intraorally for loading and calibration. the test bridges were incorporated in the patient's mouth and calibrated in vivo using variable loads. the recording system was a special intensifying and processing syste ... | 2009 | 2772595 |
| lyme disease concurrent with human immunodeficiency virus infection. | 1989 | 2773968 | |
| performance and well-being under tilting conditions: the effects of visual reference and artificial horizon. | it is generally agreed that the incidence of motion sickness in sailors working below deck is higher than in sailors who have the horizon as a visual reference on the bridge. this study investigated the possible beneficial effect of a projected artificial horizon as a means to prevent seasickness. twelve subjects were exposed to angular motion in a tilting room under three experimental conditions: a) with the windows covered, allowing no visual reference from the outside world; b) with the windo ... | 2009 | 2775135 |
| a comparison of the effects of morphine on 5-ht metabolism in the periaqueductal gray, ventromedial medulla and medullary dorsal horn: in vivo electrochemical studies in freely moving rats. | the effect of systemic morphine on serotonin (5-ht) metabolism within the dorsal raphe nucleus (drn) has been investigated by in vivo 5-hydroxyindole electrochemical (peak '3') detection in freely moving rats. morphine caused a weak and delayed, but naloxone-reversible, increase in peak '3'. this increase was poorly, if at all, correlated with the morphine-induced analgesia. finally, stress and/or noxious stimulation had no effect on this signal. these results are compared with our previous stud ... | 1989 | 2776031 |
| coaggregation of fusobacterium nucleatum, selenomonas flueggei, selenomonas infelix, selenomonas noxia, and selenomonas sputigena with strains from 11 genera of oral bacteria. | twenty-eight strains of fusobacterium nucleatum and 41 selenomonas strains, including s. sputigena (24 strains), s. flueggei (10 strains), s. infelix (5 strains), and s. noxia (2 strains), were tested for their ability to coaggregate with each other and with 49 other strains of oral bacteria representing actinobacillus, actinomyces, bacteroides, capnocytophaga, gemella, peptostreptococcus, porphyromonas, propionibacterium, rothia, streptococcus, and veillonella species. selenomonads coaggregated ... | 1989 | 2777378 |
| inhibition of coaggregation between fusobacterium nucleatum and porphyromonas (bacteroides) gingivalis by lactose and related sugars. | the coaggregation of fusobacterium nucleatum pk1594 and porphyromonas (bacteroides) gingivalis pk1924 was inhibited equally well by lactose, n-acetyl-d-galactosamine, and d-galactose, which caused 50% inhibition of coaggregation at 2 mm sugar concentration. other sugars such as d-galactosamine, d-fucose (6-deoxy-d-galactose), and alpha-methyl- and beta-methyl-d-galactosides also inhibited coaggregation. sugar specificity was apparent, since neither l-fucose, l-rhamnose, n-acetyl-d-glucosamine, n ... | 1989 | 2777379 |
| hope for aids vaccines. | 2009 | 2781299 | |
| direct measurement of basolateral membrane potentials from cells of the macula densa. | at the present time, little is known concerning the electrophysiology of the cells of the macula densa and whether or not these cells are electrically responsive to alterations in luminal fluid composition. to investigate this issue, cortical thick ascending limbs (ctal) containing macula densa and attached glomeruli were dissected from rabbit kidney and the ctal perfused in vitro. basolateral membrane potential (vbl) was measured with microelectrodes in macula densa cells and, for comparison, i ... | 1989 | 2782426 |
| effects of early maturation on fetal growth. | while the association of young maternal age with low birthweight (lbw) is well known, the contribution of early menarche to this association has never been studied. we examined the effects of early menarche (less than or equal to 11 years) on lbw and its two major underlying causes: pre-term delivery and smallness-for-gestational-age (sga). results represent a narrow chronological age range, 17-18 years, of a larger geographically based cohort of 2789 pregnant adolescents. adjusted odds ratios ( ... | 2009 | 2782851 |
| autoimmunity and second malignancy in large granular lymphocytic leukaemia. | 2009 | 2785424 | |
| bone gla protein (bgp) levels and bone turnover in rheumatoid arthritis. | bone gla protein (bgp) and other biochemical indices of bone turnover were measured in 42 female patients with rheumatoid arthritis (ra) and in a group of normal subjects matched for sex and age. mean serum bgp concentrations were significantly higher in patients with active arthritis than in patients with mild activity (p less than 0.01) and controls (p less than 0.01). no significant difference was found in serum bgp levels and in other parameters of bone turnover when the patients were strati ... | 2009 | 2786438 |
| structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neurotoxicity. ii. evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of mptp analogs. | in the accompanying paper, several tetrahydropyridine analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) were screened for their abilities to be oxidized by monoamine oxidase (mao) to pyridiniums and to produce neurotoxicity in mice. we reported that most of the analogs were oxidized by mao to pyridiniums and some of the analogs were neurotoxic. we concluded that the capacity of a tetrahydropyridine mptp analog to be oxidized by mao to a pyridinium was a necessary, but not sufficient ... | 2009 | 2786565 |
| a multidisciplinary study of onchocerciasis in bure area, ethiopia. | a clinicoepidemiological and entomological study of onchocerciasis was conducted in bure area, illubabor administrative region, in october 1987. all 1063 houses in four villages were numbered and census taken. the total population was 4119. of the total 1063 houses, 107 (10.07%) were selected by systematic random sampling and all members of these households were examined. history, physical examination, and skin biopsy were taken. of 4119 people in the area, 3555 (86.3%) were indigenous and 564 ( ... | 2009 | 2787743 |
| [septicemia caused by beta-lactamase producing fusobacterium nucleatum in a patient with neutropenia]. | 1989 | 2788381 | |
| controls of corticotrophin-releasing factor output by hypothalamic tissue from fetal sheep in vitro. | corticotrophin-releasing factor (crf) is thought to be an important physiological regulator of the pituitary-adrenal axis in fetal sheep and, as such, plays a fundamental role in the initiation of parturition in this species. however, little is known of the controls of crf secretion from the fetal hypothalamus. we looked for the presence of crf in fetal hypothalami, and examined whether the hypothalamic crf concentration or molecular species changed in relation to gestational age. we established ... | 1989 | 2788695 |
| a t-cell-specific transcriptional enhancer element 3' of c alpha in the human t-cell receptor alpha locus. | a transcriptional enhancer element has been identified 4.5 kilobases 3' of c alpha (constant region alpha chain) in the human t-cell receptor (tcr) alpha-chain locus. this enhancer is active on both a tcr v alpha (variable region alpha chain) promoter and the minimal simian virus 40 promotor in tcr alpha/beta jurkat and el4 cells but is inactive on a v alpha promoter in human tcr gamma/delta peer and molt-13 cells, clone 13 b cells, and hela fibroblasts. the enhancer has been localized to a 116- ... | 1989 | 2788889 |
| influence of age and immunization on development of gingivitis in rats. | to study the effect of age and antigenic priming on the development of gingivitis, 33 healthy rats were placed in contact with streptococcus mutans, actinomyces viscosus, fusobacterium nucleatum, and bacteroides gingivalis. on days 0, 3, 7, and 14 after inoculation, the gingival condition was judged clinically and histologically, and serum antibody titers against the bacteria were measured. the rats were divided into three groups: 1 month old, 3 months old, and 3 months old immunized. none of th ... | 1989 | 2789463 |
| enzyme linked immunosorbent assay for measuring antithrombin iii. | a competitive elisa for the measurement of antithrombin iii antigen was developed using a pure preparation of antithrombin. this two step immunoassay requires only one antibody binding step and avoids the binding of anti-antithrombin antibody to the solid phase. plasma samples measured by this elisa correlated well with measurements taken with immune electrophoresis measurements (r = 0.933); the elisa was also shown to be both sensitive and precise. | 2009 | 2794088 |
| effect of d-ala-2-me-phe-4-gly-ol-5 enkephalin on epinephrine-induced arrhythmias in the rat and the interrelationship to the parasympathetic nervous system. | the purpose of this study was to evaluate the effects of the millimicrons opioid agonist d-ala-2-me-phe-4-gly-ol enkephalin (dago) on catecholamine-induced arrhythmias. arrhythmias were produced, in the rat, by continuous infusion of epinephrine until the development of fatal arrhythmias that were usually ventricular fibrillation. intracerebroventricular (icv) administration of dago, 3 nmol, significantly (p less than 0.05) shifted to the right the relationship between epinephrine and both the o ... | 1989 | 2796596 |
| 31p-nmr study on intracellular energy transport in muscle. | 2009 | 2798486 | |
| 31p-nmr study on intracellular energy transport in muscle. | 2009 | 2798486 | |
| training inspiratory resistance in duchenne dystrophy using adapted computer games. | computer games were modified to encourage respiratory effort by two groups of patients with duchenne muscular dystrophy. one group trained during the first six months of the study, the other during the second six months. inspiratory effort was increased by their having to breathe through a mask to both start and continue the games. pulmonary function tests were done at the beginning of the trial and six, 12 and 18 months later, when forced vital capacity, respiratory muscle endurance and strengt ... | 2009 | 2806735 |
| training inspiratory resistance in duchenne dystrophy using adapted computer games. | computer games were modified to encourage respiratory effort by two groups of patients with duchenne muscular dystrophy. one group trained during the first six months of the study, the other during the second six months. inspiratory effort was increased by their having to breathe through a mask to both start and continue the games. pulmonary function tests were done at the beginning of the trial and six, 12 and 18 months later, when forced vital capacity, respiratory muscle endurance and strengt ... | 2009 | 2806735 |
| continuing medical education. | 2010 | 2807491 | |
| [panniculitis with liquefaction--a special manifestation of pfeiffer-weber-christian panniculitis]. | a case of nodular panniculitis with liquefaction in a 58-year-old woman patient is reported. it seems that pfeiffer-weber-christian disease and nodular panniculitis with liquefaction are varying expressions of the same disease entity. the relationship to cases reported in the literature is discussed. | 2009 | 2807919 |
| [panniculitis with liquefaction--a special manifestation of pfeiffer-weber-christian panniculitis]. | a case of nodular panniculitis with liquefaction in a 58-year-old woman patient is reported. it seems that pfeiffer-weber-christian disease and nodular panniculitis with liquefaction are varying expressions of the same disease entity. the relationship to cases reported in the literature is discussed. | 2009 | 2807919 |
| o-dealkylation and acetylation of sulfamethomidine by the snail cepaea hortensis. | 2009 | 2810486 | |
| [effect of glucocorticosteroid therapy on immunologic indicators in patients with sarcoidosis and idiopathic fibrosing alveolitis]. | immunological findings were recorded in 22 patients with active sarcoidosis and 12 patients with idiopathic fibrosing alveolitis. in addition, the patients' endopulmonary cytograms were considered. immunological evidence involved the use of bronchoalveolar lavage, bronchoscopy, peripheral blood. administration of corticosteroid therapy resulted in alveolitis attenuation both in sarcoidosis and fibrosing alveolitis. common features of immune response of sarcoidosis and idiopathic fibrosing alveol ... | 2009 | 2811240 |
| sleep apnea in alzheimer's disease. | mental deterioration accompanying sleep apnea has been noted frequently. because sleep apnea increases with age, such deficits raise the possibility that dementia in the elderly could be related to sleep apnea. in this study we investigated this possibility cross-sectionally by comparing respiration during sleep in 28 patients with alzheimer's disease (ad) and 25 nondemented controls. we hypothesized that higher levels of sleep apnea would be present in ad patients. our results indicated no sign ... | 2009 | 2812195 |
| sleep apnea in alzheimer's disease. | mental deterioration accompanying sleep apnea has been noted frequently. because sleep apnea increases with age, such deficits raise the possibility that dementia in the elderly could be related to sleep apnea. in this study we investigated this possibility cross-sectionally by comparing respiration during sleep in 28 patients with alzheimer's disease (ad) and 25 nondemented controls. we hypothesized that higher levels of sleep apnea would be present in ad patients. our results indicated no sign ... | 2009 | 2812195 |
| modifications of the permeability of the blood-brain barrier and local cerebral metabolism in pentobarbital- and ketamine-anaesthetized rats. | the state of deep surgical anaesthesia, induced by intraperitoneal injection of pentobarbital sodium (54 mg/kg) or ketamine hydrochloride (150 mg/kg) in the rat, was accompanied by a significant reduction in the permeability of the blood-brain barrier evaluated by calculating a unidirectional blood-to-brain constant (ki) for the circulating tracer [14c]alpha-aminoisobutyric acid. pentobarbital-induced anaesthesia was also characterized by a widespread and marked depression of local cerebral gluc ... | 1989 | 2812289 |
| modifications of the permeability of the blood-brain barrier and local cerebral metabolism in pentobarbital- and ketamine-anaesthetized rats. | the state of deep surgical anaesthesia, induced by intraperitoneal injection of pentobarbital sodium (54 mg/kg) or ketamine hydrochloride (150 mg/kg) in the rat, was accompanied by a significant reduction in the permeability of the blood-brain barrier evaluated by calculating a unidirectional blood-to-brain constant (ki) for the circulating tracer [14c]alpha-aminoisobutyric acid. pentobarbital-induced anaesthesia was also characterized by a widespread and marked depression of local cerebral gluc ... | 1989 | 2812289 |
| lack of correlation of maternal human immunodeficiency virus infection with neonatal malformations. | a malformation syndrome has been proposed in infants with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome-related complex secondary to congenital infection with human immunodeficiency virus (hiv) in the united states and europe. to determine whether embryopathy is detectable in hiv-exposed african infants, 85 infants of hiv-seropositive mothers and 98 infants of hiv-seronegative mothers in nairobi, kenya, were examined for minor and major anomalous features shortly after ... | 1989 | 2812915 |
| [intestinal fistula in crohn disease]. | the treatment of patients with crohn's disease (cd) presenting intestinal fistulas is debated. a retrospective analysis was made of the treatment of 26 patients with crohn's disease who had a total of 37 fistulas: 28 internal and 9 external. in 19 patients the fistulas were single and in 7 multiple; in most patients the fistula originated on the terminal ileum. crohn's disease was ileal in 10 patients, ileocolonic in 15 and exclusively colonic in 1, and the evolution of the disease from the onse ... | 2009 | 2813899 |
| [intestinal fistula in crohn disease]. | the treatment of patients with crohn's disease (cd) presenting intestinal fistulas is debated. a retrospective analysis was made of the treatment of 26 patients with crohn's disease who had a total of 37 fistulas: 28 internal and 9 external. in 19 patients the fistulas were single and in 7 multiple; in most patients the fistula originated on the terminal ileum. crohn's disease was ileal in 10 patients, ileocolonic in 15 and exclusively colonic in 1, and the evolution of the disease from the onse ... | 2009 | 2813899 |
| disease response to tobacco mosaic virus in transgenic tobacco plants that constitutively express the pathogenesis-related pr1b gene. | correlation of the temporal and spacial pattern of induction of the pathogenesis-related (pr) genes pr1a, pr1b, and pr1c with viral infections in certain tobacco cultivars has implicated pr proteins in viral disease resistance. to test whether the pr1 proteins of tobacco are involved in viral resistance, transgenic nicotiana tabacum plants were constructed which constitutively express the pr1b gene. this protein was secreted from cells of transgenic plants and accumulated in the extracellular sp ... | 1989 | 2815592 |
| disease response to tobacco mosaic virus in transgenic tobacco plants that constitutively express the pathogenesis-related pr1b gene. | correlation of the temporal and spacial pattern of induction of the pathogenesis-related (pr) genes pr1a, pr1b, and pr1c with viral infections in certain tobacco cultivars has implicated pr proteins in viral disease resistance. to test whether the pr1 proteins of tobacco are involved in viral resistance, transgenic nicotiana tabacum plants were constructed which constitutively express the pr1b gene. this protein was secreted from cells of transgenic plants and accumulated in the extracellular sp ... | 1989 | 2815592 |
| smoking and other tobacco use. | 1989 | 2815598 | |
| smoking and other tobacco use. | 1989 | 2815598 | |
| [ways for further improving the primary medical chart]. | 2009 | 2815611 | |
| [ways for further improving the primary medical chart]. | 2009 | 2815611 | |
| use of nude (athymic) mice for the study of hypertrophic scars and keloids: vascular continuity between mouse and implants. | hypertrophic scars and keloids appear to be unique to humans since animals are not known to form these lesions. therefore, in an effort to develop an experimental model for their study, implants of these human lesions were made in nude (athymic) mice (nu/nu) in suprascapular subcutaneous pockets. the implants were recovered from 2 to 246 days. by histological and fine structural parameters all implants remained viable and their morphological character was maintained. selected mice were injected ... | 1989 | 2817436 |
| a study suggesting two kinds of information processing of the sexual response. | genital and subjective sexual arousal in response to sexual imagery was studied. in a previous study subjects who were encouraged to process information on sexual stimuli and sexual responses were more sexually aroused than subjects encouraged to process information on sexual stimuli only. in the present study, the reverse effect was found in subjects who had received further verbal training to differentially process information on sexual stimuli or responses. this suggests two different kinds o ... | 2010 | 2818173 |
| clinical use of differential lung ventilation in the treatment of asymmetric lung injury: report of a case. | successful treatment of a 26-year-old male with asymmetric lung injury following a traffic accident is described. the patient was admitted with head injuries, right lung contusion, right pneumothorax, and multiple rib fractures (right 1-9). he developed a left pneumohemothorax and complete atelectasis of the lower lobe of the left lung two days later. conventional mechanical ventilation with and without positive end-expiratory pressure (peep), supplemented by repeated therapeutic bronchoscopy, f ... | 2009 | 2818713 |
| [selected aspects of acid and temperature resistance of the bovine leukosis virus]. | 1987 | 2820338 | |
| the molybdenum-pterin binding protein is encoded by a multigene family in clostridium pasteurianum. | there are three variants of the molybdenum-pterin binding protein (mop) encoded by three distinct genes in clostridium pasteurianum. nucleotide sequence analysis shows that the three mop genes have greater than 90% homology at the nucleotide level. upstream from the coding region of each mop gene are potential promoter consensus sequences. analysis of mop purified from cells grown under nitrogen-fixing conditions indicates all three genes are expressed. sequence analysis of the three mop genes a ... | 1987 | 2820842 |
| separation and function of neutrophil karyogranuloplasts and comparison with cytoplasts and intact cells. | since neutrophil cytoplasts lacking nucleus and granules were first prepared by centrifuging neutrophils over a discontinuous ficoll gradient containing cytochalasin b, several functional deficits have been reported in these cytoplasts. although these functional deficits have been considered to originate from the absence of organelles, cell damage during preparation could not be excluded. therefore, in the following experiments the ficoll gradient was modified to isolate both cytoplasts and kary ... | 2010 | 2820878 |
| identification of an additional sendai virus non-structural protein encoded by the p/c mrna. | peptide antiserum and monoclonal antibodies have detected a previously unrecognized small non-structural protein in sendai virus-infected cells. this protein, designated x, appears to represent the c-terminal 95 amino acids of the p protein reading frame. the x protein appears to be almost as abundant as the p protein on a molar basis in vivo. no evidence of a precursor-product relationship between the x and p proteins could be found. | 1987 | 2821189 |
| deferoxamine induced decreases of lipid peroxides in rheumatoid arthritis. | eleven patients with rheumatoid arthritis (ra) were treated with intraarticular deferoxamine or placebo to test the hypothesis that iron chelation decreased hydroxyl radical mediated lipid peroxidation in ra. intraarticular administration of deferoxamine 100 mg resulted in predominantly systemic effects with decreased serum ferritin and decreased serum levels of lipid peroxidation products. similar changes were not detected in synovial fluid at this dose. iron chelation with deferoxamine may pro ... | 2010 | 2822924 |
| virological implications of the use of primates in xenotransplantation. | 1987 | 2823433 | |
| virological implications of the use of primates in xenotransplantation. | 1987 | 2823433 | |
| effects of tilomisole, indomethacin and levamisole on regulation of epstein barr virus-induced b cell proliferation by peripheral blood mononuclear cells from normal individuals and patients with rheumatoid arthritis. | when activated in autologous mixed leukocyte reactions (auto-mlr) in vitro, t cells from normal individuals produce a suppressor factor(s) which inhibits the epstein-barr virus (ebv)-induced proliferation of normal b cells. in contrast, t cells from patients with rheumatoid arthritis (ra) are deficient in their ability to generate this suppressor factor in auto-mlr. addition of tilomisole (wy-18,251; 33(p-chlorophenyl)thiazolo[3,2-a]benzimidazole-2-acetic acid) to the auto-mlr (0.1-100 microgram ... | 1987 | 2825478 |
| effects of tilomisole, indomethacin and levamisole on regulation of epstein barr virus-induced b cell proliferation by peripheral blood mononuclear cells from normal individuals and patients with rheumatoid arthritis. | when activated in autologous mixed leukocyte reactions (auto-mlr) in vitro, t cells from normal individuals produce a suppressor factor(s) which inhibits the epstein-barr virus (ebv)-induced proliferation of normal b cells. in contrast, t cells from patients with rheumatoid arthritis (ra) are deficient in their ability to generate this suppressor factor in auto-mlr. addition of tilomisole (wy-18,251; 33(p-chlorophenyl)thiazolo[3,2-a]benzimidazole-2-acetic acid) to the auto-mlr (0.1-100 microgram ... | 1987 | 2825478 |
| the versatility of hydroxyapatite blocks in maxillofacial surgery. | there is considerable interest at present in the potential role of calcium hydroxyapatite as a biomaterial for bone augmentation in oral and maxillofacial surgery. most of the published work has been on the particulate form, mainly in alveolar ridge procedures. however, hydroxyapatite is also available as solid or porous blocks. the blocks are more predictable in their use than are the particles, and are adaptable and versatile. this paper reviews the biological behaviour of the material and dis ... | 2010 | 2825758 |
| opioid receptors inhibit the adenylate cyclase in guinea pig cochleas. | the effects of mu- and delta-preferring agonists on adenylate cyclase activity have been investigated in vitro in homogenates of guinea pig cochleas. morphine, leu-enkephalin, d-ala2, n-methyl-phe4, gly-ol5-enkephalin (dago) and d-ser2-leu-enkephalin-thr (dslet) each inhibited the synthesis of cyclic amp. this effect was reversed by naloxone which had a greater affinity in blocking the effect of the mu-preferring agonists (morphine, dago) than in blocking the effect of the delta-preferring agoni ... | 1987 | 2825909 |
| opioid receptors inhibit the adenylate cyclase in guinea pig cochleas. | the effects of mu- and delta-preferring agonists on adenylate cyclase activity have been investigated in vitro in homogenates of guinea pig cochleas. morphine, leu-enkephalin, d-ala2, n-methyl-phe4, gly-ol5-enkephalin (dago) and d-ser2-leu-enkephalin-thr (dslet) each inhibited the synthesis of cyclic amp. this effect was reversed by naloxone which had a greater affinity in blocking the effect of the mu-preferring agonists (morphine, dago) than in blocking the effect of the delta-preferring agoni ... | 1987 | 2825909 |
| modulating action of cyclic amp on the expression of two sos genes in escherichia coli k-12. | ultraviolet irradiation and cyclic amp treatment produce a synergistic effect on the induction of the cle1 gene (coding for bacteriocin cole1) in wild-type strains of escherichia coli. on the other hand, cyclic amp does not affect the uv-mediated induction of the reca, sfia, and umudc genes. growth in the presence of glucose or glycerol does not affect the factor of amplification of the expression of the cle1 gene in uv-irradiated cells of the wild-type strain. although, in cultures not treated ... | 1987 | 2825953 |
| modulating action of cyclic amp on the expression of two sos genes in escherichia coli k-12. | ultraviolet irradiation and cyclic amp treatment produce a synergistic effect on the induction of the cle1 gene (coding for bacteriocin cole1) in wild-type strains of escherichia coli. on the other hand, cyclic amp does not affect the uv-mediated induction of the reca, sfia, and umudc genes. growth in the presence of glucose or glycerol does not affect the factor of amplification of the expression of the cle1 gene in uv-irradiated cells of the wild-type strain. although, in cultures not treated ... | 1987 | 2825953 |
| subcellular localization of enzymes in streptomyces aureofaciens and its alteration by benzyl thiocyanate. i. phosphatases and atp-glucokinase. | mycelia of a low- and a high-production strain of streptomyces aureofaciens were converted into protoplasts and divided into five subcellular fractions in order to localize exopolyphosphatases (ec 3.6.1.11), triphosphatase (ec 3.6.1.25), inorganic diphosphatase (ec 3.6.1.1), apyrase (ec 3.6.1.5) and glucokinase (ec 2.7.1.2). the highest specific activity of enzymes hydrolyzing polyphosphates was found in cytoplasmic vesicles and membranes. triphosphatase was detected in the periplasmic fraction. ... | 1987 | 2826319 |
| the sequence of chick alpha-actinin reveals homologies to spectrin and calmodulin. | we have sequenced a cdna, isolated from a chick embryo fibroblast lambda gt11 library, that encodes all 887 amino acids of alpha-actinin. sequence from 10 different peptides from chick smooth muscle alpha-actinin was found to match that derived from the cdna. the deduced protein sequence can be divided into three distinct domains: (a) the n-terminal 240 amino acid contains a highly conserved region (compared with dictyostelium alpha-actinin) which probably represents the actin-binding domain, (b ... | 1987 | 2826427 |
| polymorphonuclear leukocyte inhibition by therapeutic concentrations of theophylline is mediated by cyclic-3',5'-adenosine monophosphate. | although theophylline has been used for many years as a principal agent in treatment of reversible obstructive airway disease, the mechanism of drug activity at therapeutic concentrations remains unclear. because inflammatory mediators generated by polymorphonuclear leukocytes (pmn) may be important in the pathogenesis of airway hyperreactivity, the effects of theophylline upon pmn activation were studied. theophylline (9 micrograms/ml, 50 microm) inhibited pmn leukotriene b4 generation by 50%, ... | 2010 | 2827546 |
| immunobiological activities of a porin fraction isolated from fusobacterium nucleatum atcc 10953. | from fusobacterium nucleatum atcc 10953 cell envelope fraction whose inner membranes had been removed by treatment with sodium n-lauroyl sarcosinate, an outer membrane protein (37,000 mr in a native state) was prepared by extraction with lithium dodecyl sulfate. the protein thus obtained showed distinct porin activity, namely, the ability to form hydrophilic diffusion pores by incorporation into the artificial liposome membrane. the porin fraction exhibited strong immunobiological activities in ... | 1988 | 2831155 |
| evidence for a na+/h+ antiport in stomach smooth muscle cells. | single smooth muscle cells were isolated from circular muscle of the canine gastric corpus by collagenase incubation. cytoplasmic ph (phi) of these cells was measured fluorometrically using the trapped dye 2',7'-bis(carboxyethyl)-5,6-carboxyfluorescein. cells were examined for their na+/h+ exchange activity after intracellular acidification. cells acid-loaded by propionate exposure, the nh4+ prepulse technique or suspension in a na+-depleted medium regained almost normal phi upon exposure to a n ... | 1988 | 2831889 |
| high-performance liquid chromatographic separation and immunological characterization of soluble bovine viral diarrhea virus antigen. | sodium dodecyl sulphate-polyacrylamide gel electrophoresis and western blot analysis of the protein extracts from bovine viral diarrhea virus (bvdv, singer strain) infected primary calf testicle cells (soluble antigen) showed the presence of four virus specific polypeptides of 105, 90, 84 and 67 kilodaltons (kd) the 84-kd being the most abundant. anion-exchange high-performance liquid chromatography (hplc) of soluble antigen separated the virus specific polypeptides in individual peaks while the ... | 1988 | 2832429 |
| nucleic acid sandwich hybridization in detection of hpv 16 dna: technique and its clinical application. | nucleic acid sandwich hybridization technique was used for detection of hpv 16 specific dna in cervical scrapes. alternating hpv 16-psti fragments were cloned into plasmid pbr322 and phage m13mp10. pbr322-clones were used as 32p-labelled probe reagents and the m13mp10 clones as catching reagents in the assay. the detection limit of the test proved to be 1-5 x 10(5) hpv 16 molecules per test. a weak cross reaction was seen with hpv 31 dna but not with the other types tested, e.g. hpv 6, 11, 18 an ... | 2010 | 2832436 |
| insulin-like growth factor i binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver. | insulin-like growth factor-i (igf-i) in human hepatoma cells (hep-g2) has, in addition to its effect on cell growth, short-term metabolic effects acting through its own receptor. we have demonstrated that normal human hepatocytes, compared with hep-g2 cells, have virtually no igf-i binding sites. because the rate of growth is the major difference between the hepatoma and the normal liver, we asked if normal liver might express igf-i binding sites under physiologic growth conditions. indeed, wher ... | 1988 | 2832449 |
| [hole-shaped defect in the scapula]. | 2010 | 2836918 | |
| construction of an ileal reservoir in patients with a previous straight endorectal ileal pull-through. | a decade has passed since martin and associates presented the first series of endorectal ileal pull-through (pt) procedures with straight ileoanal anastomosis for treatment of ulcerative colitis and polyposis. during the ensuing years, several medical centers have reported their results using the pt. although some children have experienced good results, the majority of adults and children have had severe problems associated with high stool frequency, urgency, and incontinence. between 1977 and 1 ... | 2009 | 2839124 |
| construction of an ileal reservoir in patients with a previous straight endorectal ileal pull-through. | a decade has passed since martin and associates presented the first series of endorectal ileal pull-through (pt) procedures with straight ileoanal anastomosis for treatment of ulcerative colitis and polyposis. during the ensuing years, several medical centers have reported their results using the pt. although some children have experienced good results, the majority of adults and children have had severe problems associated with high stool frequency, urgency, and incontinence. between 1977 and 1 ... | 2009 | 2839124 |
| a substituted thieno[3.4-d]imidazole versus substituted benzimidazoles as h+, k+-atpase inhibitors. | s 3337, 2-(2-ethylaminobenzylsulfinyl)-5,6-dimethoxybenzimidazole, and s 1924, 2-(5-methyl-2-picolylsulfinyl)-1h-thieno[3.4-d]imidazole, are members of new classes of h+, k+-atpase inhibitors. their effects on h+, k+-atpase and 14c-aminopyrine uptake in gastric glands were studied as well as in vivo in pylorus-ligated rats, stomach-lumen-perfused rats and heidenhain pouch dogs. their inhibitory effects were compared with the effect of omeprazole. in pylorus-ligated rats the two compounds showed ... | 1988 | 2841691 |
| a method to detect the in vitro modification of serum beta-2-microglobulin in health and disease. | the electrophoretically fast moving form of beta-2-microglobulin (alpha-b2m) was shown by crossed immunoelectrophoresis to be produced in vitro after incubation at room temperature and was not present in freshly drawn sera. a radioisotopic assay was developed to measure this conversion to alpha-b2m in sera from 14 healthy individuals and from 208 patients with benign and malignant disease. the activity was present in all the sera tested and the levels were significantly higher in sera from patie ... | 2009 | 2846212 |
| a method to detect the in vitro modification of serum beta-2-microglobulin in health and disease. | the electrophoretically fast moving form of beta-2-microglobulin (alpha-b2m) was shown by crossed immunoelectrophoresis to be produced in vitro after incubation at room temperature and was not present in freshly drawn sera. a radioisotopic assay was developed to measure this conversion to alpha-b2m in sera from 14 healthy individuals and from 208 patients with benign and malignant disease. the activity was present in all the sera tested and the levels were significantly higher in sera from patie ... | 2009 | 2846212 |
| [a case of hepatocellular carcinoma with intratumoral gas formation detected by plain abdominal x-ray film]. | 2010 | 2846919 | |
| role of absorptive and secretory processes in hydration of the airway surface. | in the conducting airways, epithelial electrolyte transport processes play an important role in controlling the quantity and the composition of the airway surface solution layer. hydration of the airway surface appears to promote effective mucociliary clearance and to influence the rheology of mucins, and together these factors provide a major mechanism for airway defense. the cellular processes governing absorption and secretion of salt are similar, if not identical, to those that have been des ... | 2010 | 2849352 |
| ecology of colorado tick fever. | 1988 | 2849373 | |
| enzymic capacities of amyloplasts from wheat (triticum aestivum) endosperm. | lysates of protoplasts from the endosperm of developing grains of wheat (triticum aestivum) were fractionated on density gradients of nycodenz to give amyloplasts. enzyme distribution on the gradients suggested that: (i) starch synthase and adp-glucose pyrophosphorylase are confined to the amyloplasts; (ii) pyrophosphate: fructose-6-phosphate 1-phosphotransferase and udp-glucose pyrophosphorylase are confined to the cytosol; (iii) a significant proportion (23-45%) of each glycolytic enzyme, from ... | 2010 | 2849412 |
| [role of alpha-1 and alpha-2-adrenoreceptors in achieving the compensatory response of the hemostasis system to plasmin]. | 1988 | 2849566 | |
| antiviral chemoprophylaxis for cytomegalovirus infection. | 1988 | 2849602 | |
| preparation by direct metal exchange and kinetic study of active site metal substituted class i and class ii clostridium histolyticum collagenases. | active site metal substitutions for both gamma- and zeta-collagenases from clostridium histolyticum have been made by direct metal exchange. the incubation of co(ii), cu(ii), ni(ii), cd(ii), and hg(ii) with these native collagenases results in changes in activity that parallel those observed for the reconstitution of the respective apoenzymes with these metal ions. for both collagenases, the exchange reactions with co(ii) and cu(ii) are complete within 1 min. however, the changes in activity obs ... | 1988 | 2849992 |
| hematometra complicating hormone replacement therapy after radiation for cervical carcinoma. | hematometra developed in a patient receiving sequential estrogen-progestogen hormone replacement therapy following radiation for cervical carcinoma. diagnosis, treatment and therapeutic recommendations are discussed. | 2010 | 2851962 |
| [ultrastructural and immunohistochemical studies on pleomorphic adenoma and clear cell adenoma arising from salivary gland]. | 2010 | 2855893 | |
| maternal mortality--a neglected tragedy. where is the m in mch? | 2009 | 2861534 | |
| myoglobin in the heart tissue of fishes lacking hemoglobin. | myoglobin has been identified in the heart tissue of three species of antarctic icefish, chaenocephalus aceratus, pseudochaenichthys georgianus and chaenodraco wilsoni. quantitative analysis shows myoglobin concentrations that are substantially lower than other teleost fish. a simple and accurate method for the direct measurement of myoglobin in tissue is described. | 1985 | 2863077 |
| [management of degenerative changes in the femoro-patellar joint]. | 2010 | 2863426 | |
| bone marrow under attack. | 2010 | 2863550 | |
| rheumatoid arthritis and schizophrenia: are they mutually exclusive? | the relationship between schizophrenia and rheumatoid arthritis has been explored in a number of studies. it has been claimed that the two disorders are mutually exclusive. review of the literature indicates that the two conditions seldom coexist. the underlying mechanisms responsible for the infrequent coexistence of schizophrenia and rheumatoid arthritis are far from clear. however, various hypotheses have been proposed to explain the negative correlation between the two diseases. | 2010 | 2863874 |
| [limitation of phage multiplication by microbes of the genus bordetella]. | possible causes limiting the multiplication of bordetella phages or inducing their restriction, such as the influence of lysogenic immunity and the restriction-modification (r-m) system or the incompatibility of the receptor apparatus, have been studied. the limitation of the multiplication of phages by some b. bronchiseptica and b. pertussis strains has been shown to be due to the presence of the r-m system and lysogenic immunity. in five b. bronchiseptica strains and two b. pertussis strains s ... | 1985 | 2868594 |
| long-term experience with terazosin for treatment of mild to moderate hypertension. | two hundred twenty-six patients with mild to moderate hypertension were treated with terazosin in an open, multicenter study to determine the drug's long-term efficacy and safety. all patients had previously received terazosin in a short-term study; 66 patients entered from later short-term studies and had experienced a 7 mm hg decrease in supine diastolic blood pressure in response to terazosin. terazosin was administered once or twice daily either alone or in combination with a diuretic and/or ... | 2010 | 2872810 |
| effectiveness of omeprazole in seven patients with zollinger-ellison syndrome resistant to histamine h2-receptor antagonists. | the inhibitory effect of omeprazole, a benzimidazole derivative, on gastric acid secretion was investigated in seven patients with zollinger-ellison syndrome resistant to treatment with large doses of histamine h2-receptor antagonists administered alone or in combination with pirenzepine. in two patients with an acute form of the syndrome, rapid control of acid overproduction was achieved with 180-mg intravenous and 120-mg oral daily doses, respectively. the other five patients, who were free of ... | 2009 | 2873001 |
| food incentives to improve clinic attendance. | 2010 | 2873484 | |
| [the relation between peptic ulcer and antral g and d cells]. | 2009 | 2874960 | |
| [the relation between peptic ulcer and antral g and d cells]. | 2009 | 2874960 | |
| [activity of cefotetan against anaerobic bacteria]. | we determined the susceptibility to antibiotics of 64 strains of obligate anaerobes. tested bacterial strains were as follows: 28 bacteroides fragilis, 22 fusobacterium nucleatum, 10 clostridium perfringens, and 4 bacteroides bivius. tested antibiotics were cefotetan, cefoxitin and piperacillin. cefotaxime was tested against 20 bacteroides fragilis strains. bacteroides fragilis, which is the most resistant species, was susceptible to cefotetan, cefoxitin and piperacillin, with comparable mics fo ... | 1986 | 2877431 |
| excitatory amino acids and the blood-brain barrier (bbb). | 2010 | 2878562 | |
| homocysteic acid, an endogenous agonist of nmda-receptor: release, neuroactivity and localization. | 1986 | 2878563 | |
| [treatment tactics in fractures of the midfoot]. | metatarsal fractures can occur as isolated lesions in combination with injuries of the ipsilateral tarsus, or in chain injuries of the lower extremity, or within a polytrauma. the choice of surgical or conservative therapy depends significantly on localisation and dislocation of the fracture (especially the involvement of the metatarsus i or v), as well as on the extent of the primary or expected soft part damage. from 1974 to 1984, 137 patients with metatarsal fractures were treated as in patie ... | 2010 | 2879425 |
| sulfasalazine in rheumatoid arthritis. a double-blind, placebo-controlled trial. | sulfasalazine (ssz), 3 gm daily, was compared with placebo for treatment of rheumatoid arthritis, in a 15-week randomized, parallel, double-blind trial. joint tenderness and swelling, morning stiffness, grip strength, and pain score all showed significantly more improvement with ssz than with placebo. adverse effects, particularly gastrointestinal reactions, led to withdrawal from the study of 28% of the patients who had been receiving ssz, but these effects were all readily reversible and not l ... | 2010 | 2879544 |