Publications

autologous bone marrow transplantation in patients with aml in second complete remission (cr).		2009	2653505
simulation of ionic transport mediated by membrane proteins for educational purposes.	an interactive pascal program for use in the ibm-pc and compatible computers is presented. it simulates the activation of integral membrane proteins involved in ionic transport. the program allows variation of the number of transport proteins, ionic concentrations, permeability ratios, voltage dependence of permeabilities and temperature. a separate procedure for simulation of na+-k+ pumps has been included considering their relevance in physiology. the main purpose of the present program is to ...	2009	2653720
exocrine pancreatic function after gastrectomy. specificity of indirect tests.	we compared intraindividually the specificity of indirect pancreatic function tests before and after total (n = 4; roux-en-y) or subtotal (n = 6; billroth ii) gastrectomy. before gastrectomy only 1 patient showed a falsely pathological result with the pancreolauryl test (90% specificity), while the results of all the other tests were correctly normal (100% specificity using the usual cutoff limits). after gastrectomy the respective specificities were as follows: pancreolauryl test 10%, bentiromi ...	2009	2656361
exocrine pancreatic function after gastrectomy. specificity of indirect tests.	we compared intraindividually the specificity of indirect pancreatic function tests before and after total (n = 4; roux-en-y) or subtotal (n = 6; billroth ii) gastrectomy. before gastrectomy only 1 patient showed a falsely pathological result with the pancreolauryl test (90% specificity), while the results of all the other tests were correctly normal (100% specificity using the usual cutoff limits). after gastrectomy the respective specificities were as follows: pancreolauryl test 10%, bentiromi ...	2009	2656361
submalar augmentation. an alternative to face-lift surgery.	submalar augmentation is a new approach that effectively deals with many of the problems encountered in midfacial rejuvenation. this study reports the results of 78 patients who were successfully treated over 6 years by submalar augmentation. this procedure consists of inserting newly designed silastic (silicone rubber) implants over the midface to create the appearance of restoring the vibrant and youthful fullness of the middle third of the face while avoiding distortion of normal facial anato ...	2007	2660851
nasopharyngeal cysts. report of seven cases with review of the literature.	a series of seven patients with nasopharyngeal cysts is presented. a review of the pertinent literature and a description of the clinical, radiologic, and pathologic features of these lesions are also included. the role of computed tomography in differentiating nasopharyngeal cysts from other pathologic entities, as well as the importance of surgery as an elective method of treatment, is specifically emphasized.	2008	2660853
enhancement of the infectivity of fusobacterium necrophorum by other bacteria.	necrobacillosis is caused by fusobacterium necrophorum (fn), but other organisms are often present in the lesions. their possible role was studied in experiments made with a virulent fn strain which, by itself, produced fatal necrobacillosis in mice provided that large doses (greater than 10(6) organisms, subcutaneously) were given. mice were inoculated subcutaneously with fn suspended in sub-lethal doses (0.1 ml) of undiluted or diluted broth cultures of other bacteria. undiluted culture of a s ...	1989	2661253
perspectives on the risks for occupational transmission of hiv-1 in the health-care workplace.		1989	2662448
molecular genetics of duchenne and becker muscular dystrophy: emphasis on improved diagnosis.	duchenne muscular dystrophy (dmd) is a severe muscle-wasting disorder affecting 1 in 3500 males. a less severe and less common form is becker muscular dystrophy (bmd). only recently has the basic defect in dmd and bmd been recognized: a region on the human x chromosome is disrupted by mutation. the primary transcript of the region was detected, and cdna clones were isolated that encompassed the entire transcript. the sequence of the encoded protein was predicted from cdna nucleotide sequence, po ...	1989	2663232
indicator dilution time-activity curves demonstrated by rapid magnetic resonance imaging techniques and paramagnetic contrast agent.	indicator dilution time-activity curves are demonstrated using magnetic resonance imaging (mri) as the detector and a paramagnetic contrast agent as the indicator. manganese chloride was injected into a flow phantom. the nuclear magnetic resonance (mr) intensity was measured downstream. several flow rates were used. the observed mr intensity decreased as the paramagnetic indicator passed through the imaging plane. the qualitative changes of the mr intensity decrease varied in accordance with ind ...	2008	2663765
serum-free, chemically defined medium to evaluate the direct effects of growth factors and inhibitors on proliferation and function of neonatal rat cardiac muscle cells in culture.	neonatal rat cardiac myocytes were isolated and cultured to evaluate the effects of growth factors and inhibitors on proliferation, survival, and functions in a serum-free medium. insulin and transferrin in mcdb 107 nutrient medium elicited dna and protein synthesis in cells on a fibronectin-coated culture surface in serum-free medium. insulin was most effective on both dna and protein synthesis in serum-free culture conditions. the serum-free, hormone-supplemented medium eliminated the contamin ...	1989	2666383
serum-free, chemically defined medium to evaluate the direct effects of growth factors and inhibitors on proliferation and function of neonatal rat cardiac muscle cells in culture.	neonatal rat cardiac myocytes were isolated and cultured to evaluate the effects of growth factors and inhibitors on proliferation, survival, and functions in a serum-free medium. insulin and transferrin in mcdb 107 nutrient medium elicited dna and protein synthesis in cells on a fibronectin-coated culture surface in serum-free medium. insulin was most effective on both dna and protein synthesis in serum-free culture conditions. the serum-free, hormone-supplemented medium eliminated the contamin ...	1989	2666383
understanding our past to build our future.		2009	2666955
the precursor of beta-lactamase: purification, properties and folding kinetics.	the precursor of escherichia coli rtem beta-lactamase was purified to homogeneity on a milligram scale by a procedure independent of the binding properties of the protein and refolded to an active, reduced form. for comparing the folding kinetics, the wild-type enzyme was reduced and a mutant was constructed, in which the two cysteines that form a very stable disulfide bond in the rtem enzyme were both changed into alanines. the rate of folding was determined by directly measuring the increase i ...	1989	2670555
[otorhinolaryngologic aspects of adamadiades-behçet syndrome].	behçet's syndrome is a rare, progressive and systemic disease. it causes scrotal ulcers, bilateral conjunctivitis and recurrent oral aphthous ulcers. genetic factors, mechanisms of autoimmunity as well as environmental factors interact in the etiology of the syndrome, according to the most recently developed hypotheses. the diagnostic and therapeutic traps which might appear during the contemporary o.r.l. practice are presented here, considering the oral ulcers of a frequently common appearance ...	2009	2675237
report of the committee on the genetic constitution of chromosome 3.		1989	2676365
modulation of human neutrophil adherence by periodontopathic bacteria: reversal by specific monoclonal antibodies.	previous investigations by us have shown that direct interaction of fusobacterium nucleatum with polymorphonuclear neutrophils (pmns) results in the stimulation of pmn adherence whereas direct interaction with bacteroides gingivalis results in pmn suppression. in the present study, panels of monoclonal antibodies (mabs) raised against cell wall antigens of f. nucleatum and b. gingivalis were tested to determine their ability to block the modulatory effects of the bacteria in their interactions w ...	1989	2680992
a century of change in neurosurgery at johns hopkins: 1889-1989.	neurosurgical admissions to the johns hopkins hospital during the first year of its existence, the first and last years of harvey cushing's practice, the last years of walter dandy's practice, the last years of earl walker's tenure, and the current neurosurgical case load are reviewed. sixteen patients with neurosurgical problems were admitted during the first year of the hospital's existence. in the first year of harvey cushing's staff appointment, 38 neurosurgical patients were admitted. infec ...	2009	2681565
stability in the correction of dentofacial deformities: a comprehensive review.	postoperative stability of the skeletal segments repositioned during orthognathic surgery continues to challenge even the most experienced surgeons. in an attempt to establish a consensus about the direction of postsurgical movement and the methods used to prevent relapse, studies from the last 33 years were reviewed. these studies are grouped as isolated maxillary and mandibular procedures, simultaneous two-jaw procedures, and procedures used to treat syndrome/cleft palate patients.	2009	2681608
remodeling of the rat small intestinal mucosa during the suckling period.	the development of the suckling rat small intestine has been reexamined to investigate changes to cell kinetics and morphology more fully. in this period of rapid growth and reorganization, villi and crypts steadily increase in size in proximal regions; however, in distal regions a dramatic shortening of villi occurs at about 15 days. the result of this remodeling is that the normal adult proximodistal gradient of villus height is established at 15 days, migration rates in both regions increase ...	1989	2681650
quantitative bacteriology of a case of acute parotitis.	it is generally assumed that the microorganisms responsible for acute suppurative parotitis are facultative anaerobes, primarily staphylococcus aureus and streptococcus viridans. a quantitative microbiologic investigation of an aspirate of pus from the case we report revealed a microbial flora (5.1 x 10(6) cfu/ml) consisting entirely of strict anaerobes (fusobacterium nucleatum and peptostreptococcus anaerobius). the strain of f. nucleatum was sensitive to metronidazole but resistant to penicill ...	1989	2682427
[egocentric reference and represented space].	the subjective estimate of the position of the egocentric reference was measured in normal right-handed subjects. they had to point manually in the straight ahead direction at what they thought was their body's sagittal plane. a systematic leftward bias of relatively small amplitude was observed for pointings with the right hand. no such bias was observed with the left hand. in addition, fixation of a visual target located within the right or left hemispace systematically deviated the estimated ...	2008	2682938
[clinical syndromes with liver and kidney involvement in children and adults].	multiple pathogenetic mechanisms can lead to dysfunctions or malformations of the liver and kidneys in children and adults. the association of renal and hepatic abnormalities can be found in different congenital malformation syndromes. hereditary metabolic disorders are capable of alternating liver and kidney function. immunologic, toxic and septic diseases may damage both organ systems. in patients with liver cirrhosis, both glomerular and tubular dysfunctions can be observed. in the course of ...	2005	2685579
the educational process at the mount sinai school of medicine: the first 25 years.	although the charter for the school of medicine was signed in 1963, and active recruitment of faculty commenced almost immediately, the recruitment of students, in fact, did not begin until several years later, with admission of a first-year and a third-year class in september 1968. from that time to the present, the class size has increased from a small, carefully selected group of 36 first-year students to its current size of 115 students in each of the basic science years and 132 students in ...	2006	2685587
[bacterial invasion in periodontitis, is it important in periodontal treatment?].	during the progression of periodontal disease bacteria invade the epithelial lining of the gingival pocket and the underlying connective tissue. this invasion was demonstrated in acute necrotizing ulcerative gingivitis (anug), localized juvenile periodontitis (ljp), rapidly progressive periodontitis in adults (rpp) and in children with papillon-lefèvre syndrome associated periodontitis. using morphologic criteria or fluorescent antibody staining techniques spirochetes, actinobacillus actinomycet ...	1989	2685948
myosin light chain phosphorylation in 32p-labeled rabbit aorta stimulated by phorbol 12,13-dibutyrate and phenylephrine.	the mechanism(s) of force development in vascular smooth muscle following pharmacological activation of protein kinase c by phorbol esters are not known. in this study, we examined the myosin light chain phosphorylation response following stimulation by phorbol 12,13-dibutyrate (pdb) or phenylephrine in rabbit aorta which had been incubated with 32po4 in order to label atp pools. through tryptic phosphopeptide mapping of myosin light chain from intact tissue and comparison to controls using puri ...	1989	2687275
[insulin and hypertension--the mechanisms of high blood pressure during chronic insulin infusion].	the purpose of this study was to assess the effects of chronic insulin infusion on blood pressure and urinary sodium excretion in wistar rats. fifteen male wistar rats weighing about 220 g were used. the rats were housed in metabolic cage and measured urine volume. osmotic minipumps filled with insulin (0.57 u/day, insulin group, n = 9) or saline (0.014 cc/day, control group, n = 6) were implanted subcutaneously under ether anaesthesia, and blood pressure, urine volume, urinary sodium excretion ...	1989	2687519
assay for sialidase using erythrocytes and peroxidase-labeled peanut lectin.	a rapid and sensitive sialidase assay method based on peroxidase-labeled peanut lectin (pna) binding to desialylated erythrocyte is described. formalinized sheep erythrocytes were used both as a stable substrate for sialidase and as a target for the lectin. in the case of sialidases from vibrio cholerae and arthrobacter ureafaciens, a linear relationship was observed between the amount of peroxidase-labeled pna bound to erythrocytes and the enzyme amount. binding of the lectin to sialidase-treat ...	1989	2688936
the efficiency of interaction of deoxyribonucleoside-5'-mono-, di- and triphosphates with the active centre of e. coli dna polymerase i klenow fragment.	the interaction of deoxyribonucleoside-5'-mono-, di- and triphosphates with e. coli dna polymerase i klenow fragments was examined. dissociation constants of the enzyme complex with nucleotides were determined from the data on the enzyme inactivation by adenosine 2',3'-riboepoxide 5'-triphosphate. the role of nucleotide bases, phosphate groups and sugar moieties in the complex formation of nucleotides with the enzyme was elucidated. the necessity of complementary interaction of nucleotides with ...	1989	2689231
minaprine: an anticholinergic-free antidepressant? results of a controlled trial of mianserin.	minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of anticholinergic effects, cardiotoxicity, drowsiness, and weight gain. minaprine (100 mg t.d.s. and 100 mg b.d.) was compared with mianserin (20 mg t.d.s.) in 117 depressed patients, and all three regimes produced significant reductions in scores on the hrsd at the end of six weeks' treatment. there were no anticholinergic effects, but there was a significantly greater incidence of drowsiness with mianserin th ...	2009	2690999
the acid-etch retained rest for removable partial dentures.	this article will describe the techniques for composite and metal rests. it will also discuss a clinical follow-up of 18 patients who have had metal or composite rests in place from three to 18 months.	2009	2691082
renal function, glycemic control and perindopril in diabetic patients.	we studied the effect of perindopril, administered for a period of 9 months, on renal function, albuminuria and glycemic control of diabetic subjects with mild-to-moderate hypertension. after 1 month of placebo, 40 insulin-treated patients were divided into 3 groups based on the level of albuminuria. group i had normal albuminuria (less than 15 mg/24 hr), group ii had pathological microalbuminuria (15-150 mg/24 hr) and group iii had macroproteinuria (greater than 150 mg/24 hr). they were given p ...	2009	2691128
from the beginning: an historical review of medical art.		2006	2691550
falciparum malaria--present day problems. an experience with 425 cases.	clinical details and present day problems encountered in 425 cases of falciparum malaria (pf) are reported. 10.11% had taken chloroquine prior to reporting to us. parasitic count done in 23.05% cases lacked correlation with severity of disease. pattern of fever varied markedly but 5.4% were afebrile throughout and presented only with bodyache and malaise. apyrexial spell was noted in 5.64%. 28.70% had typical facial looks of anaemia and sallow complexion. cerebral symptoms were noted in 3.05%. o ...	1989	2693436
the microbiology of hiv-associated periodontal lesions.	2 intraoral lesions associated with human immunodeficiency virus (hiv) infection have recently been described: an atypical gingivitis and a rapidly progressive periodontitis. the microbiota associated with these gingival and periodontal lesions was investigated. subgingival plaque samples were taken from 45 hiv-seropositive homosexual men and from 44 hiv-seronegative control subjects. each sampled site was clinically and radiographically classified as hiv-associated gingivitis, hiv-associated pe ...	1989	2693496
[characterization of monoclonal antibodies to toxoplasma gondii].	proteins of toxoplasma lysate were separated by sds-polyacrylamide gel electrophoresis with subsequent transfer to a nitrocellulose sheet by electrophoretic blotting. the range of protein bands was 6-100 kd. monoclonal antibodies 1b2, 5b10, 4f6 reacted with antigens of 21 kd, 35 kd and 66 kd. monoclonal antibodies reacted with major antigens of the rh-tachyzoiten surface and hanr-cysts.	1989	2694652
propranolol.		2009	2695466
[proposal for a new therapeutic strategy in high genital infections].	78 cases of acute salpingitis were treated with the association oflocet-augmentin in a multicenter study. an accurate clinical and bacteriological evaluation was carried out prior to the treatment and a control laparoscopy was performed in 31 cases. a chlamydia infection was responsible in 56 p. cent of the cases; only one bacteria was identified in 56 cases and an association of two or three bacteria in 15 cases; in 7 cases, no bacteria was identified. the antibiotic association was effective i ...	1989	2696066
pediatric liver transplantation: diagnostic pathology.		2008	2697853
[clinico-diagnostic significance of enzyme activity determinations].		2009	2697998
decreased plasma c-peptide to insulin molar ratio after oral glucose in elderly subjects.	to evaluate the effect of aging on hepatic extraction of insulin, peripheral plasma insulin and c-peptide levels after an oral glucose ingestion were measured in 39 non-obese healthy subjects with normal glucose tolerance test. the subjects were divided into two groups. one age group was below 30 years (n = 17) and another was above 50 years (n = 22). blood glucose level was significantly higher in elderly subjects than in young at 30 and 60 min, and insulin level was also significantly higher i ...	2009	2698354
[ultrasonic diagnosis of tumorous lesions of the liver].		2009	2698513
[influence of the lithiasic surface on the strategy: complications and results in the treatment of kidney calculi].	stone mass is a fundamental parameter that determines the approach to reno-ureteral lithiasis. reference to stone size based on a single diameter gives us an imprecise idea about stone volume. for this reason, we recommend using the term "stone surface" to express stone mass. stone surface is obtained by multiplying the longitudinal by the transversal diameter expressed in millimeters, using the plain film for radiopaque and the urogram for radiolucent calculi. stone surface is a parameter which ...	2007	2699547
[microbiological and serological investigation of periodontal disease activity].	if disease activity in periodontal disease can be determined, the therapeutic measures of periodontitis may become diverse and different from patient to patient. the purpose of the present study was to evaluate the usefulness of microbiological and serological examination of periodontopathic bacteria in detecting destructive periodontal disease activity. one hundred and forty-eight sites in 52 subjects with moderate to severe periodontitis were studied clinically. clinical parameters included pl ...	1989	2700196
[microbial flora of periodontitis and monitoring of the effect of initial preparation by immunofluorescence microscopy].	the effect of initial preparation in adult periodontitis was evaluated by changes in clinical parameters and immunofluorescence microscopic counts of periodontal disease associated bacteria. subgingival plaque samples were taken with sterilized paper points from 10 sites of 5 periodontally healthy persons and 44 sites of 23 adult periodontitis patients. twenty-one diseased sites were periodically examined after plaque control and scaling, root planing. the direct immunofluorescence technique was ...	1989	2700361
[plastic surgery in otorhinolaryngology: reconstruction flaps in oncologic surgery].		2009	2701493
pterygium colli: surgical treatment.	the authors report three cases of pterygium colli. two of them presented as part of turner's syndrome and were treated following a personal technique. the third, which was probably due to jugular lymphatic obstruction, was treated according to the butterfly excision technique of shearin.	2009	2702365
transcardiac passage of thrombus--ultrasonographic visualization.	a patient is described in whom a right atrial thrombus was seen, by two-dimensional echocardiography, in the act of embolizing into the pulmonary circulation.	2009	2702500
the role of angiotensin-converting enzyme inhibitors in the therapy of cardiovascular disease: an overview.		2009	2705642
design, expression, and crystallization of recombinant lectin from the garden pea (pisum sativum).	the propeptide form of the lectin from the garden pea (pisum sativum agglutinin) has been expressed in escherichia coli by attaching its cdna to an inducible promoter. by a number of criteria, including the ability to form dimers, hemagglutination titer, western blot, and enzyme-linked immunosorbent assay, the resulting propeptide molecule is virtually indistinguishable from the mature proteolytically processed lectin isolated from peas. preliminary crystallization experiments using the recombin ...	1989	2708344
design, expression, and crystallization of recombinant lectin from the garden pea (pisum sativum).	the propeptide form of the lectin from the garden pea (pisum sativum agglutinin) has been expressed in escherichia coli by attaching its cdna to an inducible promoter. by a number of criteria, including the ability to form dimers, hemagglutination titer, western blot, and enzyme-linked immunosorbent assay, the resulting propeptide molecule is virtually indistinguishable from the mature proteolytically processed lectin isolated from peas. preliminary crystallization experiments using the recombin ...	1989	2708344
development of personality and intelligence in children with congenital heart disease.	one hundred and twenty-eight children with congenital heart disease (chd) and 89 healthy controls were compared according to their development of personality and intelligence. presence of physical disability in daily life was the independent variable for dividing children with chd into two groups: children with physical handicap due to chd (n = 77) have lower iq scores than healthy children. unexpectedly, in the parents' opinion they show no difference in behaviour patterns. on introspective exa ...	2009	2708467
structure-function relationships in rat brainstem subnucleus interpolaris: v. functional consequences of neonatal infraorbital nerve section.	in a prior study (jacquin et al., '86c), the response properties and projections of neonatally axotomized trigeminal (v) primary afferents were studied in the adult rat. here, single-unit recording, electrical stimulation, and receptive field (rf) mapping techniques were also used to assess the functional consequences of neonatal infraorbital nerve section upon postsynaptic cells in v brainstem subnucleus interpolaris (spvi). of 904 cells studied, 385 were from normal adults and 519 were from ne ...	1989	2708594
allocation and the physician: the impacts of aging and aids.		2009	2709175
[a comparative assessment of methods of collecting and long-term storage of ixodidae ticks].	a humid bandage 130 mm wide turned to be the best kind of "chamber" for the collection of ixodidae in nature and their maintenance under laboratory conditions, as it was demonstrated by studies of ixodus persulcatus imago ticks.	2008	2710046
[a comparative assessment of methods of collecting and long-term storage of ixodidae ticks].	a humid bandage 130 mm wide turned to be the best kind of "chamber" for the collection of ixodidae in nature and their maintenance under laboratory conditions, as it was demonstrated by studies of ixodus persulcatus imago ticks.	2008	2710046
fetal cortical transplants reduce the thalamic atrophy induced by frontal cortical lesions in newborn rats.	fetal neocortical tissue was grafted into frontal cortex lesion cavities made in newborn rats. after survival periods extending up to 14 months, volumetric measurements of the total thalamus and of the lateral, medial and anterior thalamic compartments showed an amelioration of the thalamic atrophy that normally is found after cortical lesions. these results correspond to previous findings demonstrating interconnections between fetal cortical transplants and the host thalamus.	1989	2710397
fetal cortical transplants reduce the thalamic atrophy induced by frontal cortical lesions in newborn rats.	fetal neocortical tissue was grafted into frontal cortex lesion cavities made in newborn rats. after survival periods extending up to 14 months, volumetric measurements of the total thalamus and of the lateral, medial and anterior thalamic compartments showed an amelioration of the thalamic atrophy that normally is found after cortical lesions. these results correspond to previous findings demonstrating interconnections between fetal cortical transplants and the host thalamus.	1989	2710397
specific petit mal anticonvulsants reduce calcium currents in thalamic neurons.	low-threshold calcium current (ltcc) in thalamic neurons is important in generation of normal thalamocortical rhythms, and may be involved in the genesis of abnormal activities such as spike-wave discharges that characterize petit mal epilepsy. ethosuximide and dimethadione, anticonvulsants effective in petit mal, reduced the ltcc when applied to thalamic neurons at clinically relevant concentrations. therapeutic concentrations of phenytoin and carbamazepine, drugs ineffective in the control of ...	1989	2710401
the projection pattern of forepaw nerves to the cuneate nucleus of the raccoon.	the transganglionic transport of horseradish peroxidase (hrp) was used to determine the projection pattern within the cuneate nucleus of the 4 major nerves innervating the forepaw of the raccoon, a carnivore noted for its tactile and manipulative abilities. the two nerves innervating the dorsal, hairy skin and claws (the radial and dorsal ulnar nerves) projected to the marginal rim of the cuneate nucleus, but not to the middle cluster region or to the caudal region of the nucleus. the two nerves ...	1989	2710406
the projection pattern of forepaw nerves to the cuneate nucleus of the raccoon.	the transganglionic transport of horseradish peroxidase (hrp) was used to determine the projection pattern within the cuneate nucleus of the 4 major nerves innervating the forepaw of the raccoon, a carnivore noted for its tactile and manipulative abilities. the two nerves innervating the dorsal, hairy skin and claws (the radial and dorsal ulnar nerves) projected to the marginal rim of the cuneate nucleus, but not to the middle cluster region or to the caudal region of the nucleus. the two nerves ...	1989	2710406
cerebral structure in borderline personality disorder.	computed tomographic (ct) scans of brains of patients with borderline personality disorder and normal volunteers were analyzed for ventricle-brain ratios, third ventricular size, and evidence of frontal lobe atrophy. there were no significant differences between the two groups on any of these measures except for a narrower third ventricle in borderline patients, which could be accounted for by the narrower third ventricle observed in female subjects overall. while borderline patients may show si ...	2009	2710860
[spondylodiscitis caused by fusobacterium nucleatum. apropos of 1 case].		1989	2711113
isolation of fusobacterium nucleatum and electron microscopic observations of spirochetes from tropical skin ulcers in papua new guinea.	tropical ulcer is a disabling condition of the lower leg affecting mainly young adults and older children. microscopic observations of lesion material have shown fusiform bacilli and spirochetes. we used anaerobic culture techniques to isolate and identify these fusiform bacilli. electron microscopic (em) studies were performed to characterize the spirochetes. material collected on swabs was used to inoculate pre-reduced media and to prepare smears for gram staining; the swabs were placed in fix ...	1989	2712197
an evaluation of the multiple-breath nitrogen washout as a pulmonary function test in dairy cattle.	multiple-breath nitrogen washouts (mbnw) were performed with 21 adult dairy cows (seven normal cows tested on two days each, four clinically normal cows tested on six days, and ten cows with respiratory disease tested on one day each). the functional residual capacity (frc), lung clearance index (lci), becklake index (bi), mixing ratio (mr), pulmonary n2 clearance delay (pcd), index of distribution of inspiration (idi) and ventilatory efficiency (eff) were calculated for each mbnw. the lci, mr, ...	1989	2713778
an evaluation of the multiple-breath nitrogen washout as a pulmonary function test in dairy cattle.	multiple-breath nitrogen washouts (mbnw) were performed with 21 adult dairy cows (seven normal cows tested on two days each, four clinically normal cows tested on six days, and ten cows with respiratory disease tested on one day each). the functional residual capacity (frc), lung clearance index (lci), becklake index (bi), mixing ratio (mr), pulmonary n2 clearance delay (pcd), index of distribution of inspiration (idi) and ventilatory efficiency (eff) were calculated for each mbnw. the lci, mr, ...	1989	2713778
[empirical antimicrobial therapy of infection and fever episodes in children and adolescents with neutropenia caused by cytotoxic chemotherapy].	the experience with empirical antimicrobial therapy of septicemia and febrile episodes in pediatric neutropenic patients was analyzed retrospectively. between january 1985 and march 1988 in 49 patients 77 episodes were observed. bacteremia was found in 15 (20%), culture proven localized bacterial infection in 11 (14%) and clinically diagnosed bacterial infection was found in 7 (9%) of the febrile episodes. thus, 33 (43%) documented bacterial infections were observed. for initial therapy a combin ...	2009	2717190
fish oil controversy.		2009	2718495
[visual evoked potentials in the differential diagnosis of vascular and demyelinating disorders of the optic nerve].	in 21 patients with idiopathic retrobulbar neuritis (irn) the optic nerve function was assessed using visual evoked potentials under a reversible black-and-white chessboard pattern stimulation. latencies of the large positive wave p100 significantly increased in all irn patients ipsilaterally to the diseased eye and in a half of the patients contralaterally. amplitude reduction in the evoked response to the diseased eye stimulation with unaffected eye p100 parameters within the normal range was ...	2008	2718656
splenic abscess from fusobacterium nucleatum.		1989	2719435
[antibiotic sensitivity of gram-negative opportunistic bacteria isolated from the feces of newborn infants with intestinal infections].	antibiotic sensitivity of 136 pure cultures of gram negative aerobic potentially pathogenic bacteria was assayed. the bacteria were isolated from feces of newborns with intestinal infections. it was shown that the majority of the strains were resistant to 4-5 antibiotics widely used in treatment of patients. however, they were sensitive to gentamicin and polymyxin m.	2008	2730219
colonic cancer induced by 1,2-dimethylhydrazine: promotion by experimental colitis.		2009	2736203
[the obstetric risk in adolescent primiparous females].	the obstetric risks in primiparae between 12 and 17 years of age have been reviewed in cases treated at our hospital from 1982 to 1987. we looked for intrauterine foetal deaths, premature deliveries (birth weight less than 2500 g), breech presentations, preeclampsia, caesarean sectio rate, forceps rate, and thirdstage complications. the risks found in the group of 476 young primiparae were compared to those amongst the 26,768 overall deliveries during the same period. the incidence of breech pre ...	2007	2737441
clonazepam in the treatment of obsessive compulsive disorder associated with panic disorder in one patient.	the authors present the case of a 21-year-old man with obsessive compulsive disorder (ocd) complicated by panic disorder, whose ocd and panic symptoms resolved during clonazepam treatment. prior treatment with an equivalent dose of lorazepam had ameliorated his panic attacks without affecting his obsessions or compulsions. clonazepam worked with a rapidity and completeness uncharacteristic of more established treatments for ocd.	1989	2738031
concept of response factor in capillary isotachophoresis. determination of drugs in solution for intravenous injection.	twenty-six drugs in solutions for intravenous injection were determined by capillary isotachophoresis with only one calibration point for each component. the maximum deviation of the labelled concentration was 2%. a new calibration constant is introduced, viz., the response factor (rf, dimensionless), which is independent of the diameter of the capillary, the construction of the universal detector and the driving current used during detection. it is shown that the rf can be used on different equ ...	2009	2738137
differences in renal tubular toxicity of high- and low-osmolality contrast media.		2009	2739845
effects of growth factors on cytosolic free calcium concentration and dna synthesis in cultured rat aortic smooth muscle cells.	proliferation of vascular smooth muscle cells (smcs) has been considered to be an important process in the development of atherosclerosis. this study was conducted to investigate the role of cytosolic free calcium in dna synthesis of smcs stimulated by growth factors. platelet-derived growth factor (pdgf), epidermal growth factor (egf) and somatomedin-c (sm-c) increased [3h]thymidine incorporation, an index of dna synthesis, and cell number of rat aortic smcs after 36 hr of incubation. cytosolic ...	1989	2741168
effects of growth factors on cytosolic free calcium concentration and dna synthesis in cultured rat aortic smooth muscle cells.	proliferation of vascular smooth muscle cells (smcs) has been considered to be an important process in the development of atherosclerosis. this study was conducted to investigate the role of cytosolic free calcium in dna synthesis of smcs stimulated by growth factors. platelet-derived growth factor (pdgf), epidermal growth factor (egf) and somatomedin-c (sm-c) increased [3h]thymidine incorporation, an index of dna synthesis, and cell number of rat aortic smcs after 36 hr of incubation. cytosolic ...	1989	2741168
repeated hepatic ischemia as a treatment for carcinoid liver metastases.	hepatic ischemia has been used in the treatment of bilobar malignant carcinoid tumors in the liver. hepatic artery ligation, hepatic dearterialization, and embolization with nondegradable micromaterial have been followed by collateral formation and are associated with a high complication rate. to reduce this, an implantable vascular occluder permitting intermittent occlusion of the hepatic artery was used in 3 patients with bilateral malignant carcinoid in the liver, with high urinary excretion ...	2009	2741468
development and use of asbestos risk estimates.	several groups of researchers, at the request of government agencies in various countries, have reviewed the literature on the health effects of asbestos exposure and derived quantitative estimates of the risks from such exposures. because of differences in the area of responsibility of the different agencies, these estimates have inevitably been based on different assumptions concerning exposure (concentration, number of years of exposure, initial age, and number of hours per week). the lifetim ...	2009	2744842
identification by c-banding of two human prostate tumour cell lines, 1013l and du 145.	two human prostate carcinoma cell lines are easily distinguished by c-banding. du 145 has one metacentric chromosome with a large centromeric band, 1 metacentric and 2 acrocentric chromosomes with interstitial c-bands. the y chromosome was present in 48% and 42% of the cells at passages 83 and 106, respectively, whereas in 1013l only one metacentric chromosome contained distinct extra c bands--one at the centromere and one interstitially. the y chromosome was present in 72% of the cells at passa ...	1989	2744886
cancer risks due to occupational exposure to formaldehyde: results of a multi-site case-control study in montreal.	a case-control study was undertaken in montreal to investigate the possible associations between occupational exposures and cancers of the following sites: oesophagus, stomach, colo-rectum, liver, pancreas, lung, prostate, bladder, kidney, melanoma and lymphoid tissue. in total, 3,726 cancer patients and 533 population controls were interviewed to obtain detailed lifetime job histories and information on potential confounders. each job history was translated into a history of occupational exposu ...	2009	2744897
[estimation of passive smoking during pregnancy by cotinine measurement and its effect on fetal growth].	maternal cigarette smoking has been associated with some complications of pregnancy, including low birth weight and increased morbidity. recently, it has been reported that maternal passive smoking also affects the fetal environment and causes fetal growth disturbance. in this study, we aimed to investigate the effects of maternal passive smoking on pregnant women and their fetuses by measuring cotinine concentrations in maternal urine and umbilical cord blood. the results were as follows: 1) am ...	2007	2746069
[golabi rosen syndrome: a rare syndrome with imprecise nosologic limits, failure of prenatal diagnosis].		2009	2746174
psychological and environmental determinants of relapse in crack cocaine smokers.	the paper reviews approaches to relapse in the treatment of cocaine abusers. approaches reveal a common mechanism underlying relapse that involves drug craving, recall of euphoria, environmental cues, denial, myths of being able to sell or use drugs, and painful affect states necessitating use of a multifaceted clinical technique. empirical validation of a common mechanism underlying relapse establishes a typology of psychological and environmental determinants of relapse for crack cocaine smoke ...	2008	2746717
'i need you'.		2008	2748386
'i need you'.		2008	2748386
[motor disorders of the stomach excluding sequelae from surgery].		2009	2749089
thoracic actinomycosis.	nine cases of thoracic actinomycosis treated in the period 1966-1987 are reported. three of the patients presented with a clinical picture of empyema and six were admitted for suspected primary pulmonary neoplasm. no case was correctly diagnosed preoperatively. the final diagnosis was based on direct microscopy (2) or culture (1) of drained pus in the empyema cases and on histologic examination of resected tissue in the others. in one case the correct diagnosis was missed when a palpable tumour ...	2009	2749211
macrophage subpopulations in lamina propria of normal and inflamed colon and terminal ileum.	the aim of this study was to characterise human intestinal macrophages in normal and inflamed ileum and colon. immunoperoxidase staining with a panel of monoclonal antibodies and histochemical staining for acid phosphatase and non-specific esterase was performed. in the superficial lamina propria, normal colonic macrophages were larger and more strongly positive for acid phosphatase and non-specific esterase than those in normal terminal ileum. there were more macrophages staining with monoclona ...	1989	2753407
full-time coordinators meet governance head-on.		2008	2753485
[studies on the constituents of trichosanthes root. ii. constituents of roots of trichosanthes cucumeroides maxim].	from the fresh roots of trichosanthes cucumeroides maxim., three new triterpenoid glycosides with a bitter taste were obtained together with methyl palmitate, palmitic acid, alpha-spinasterol, stigmast-7-en-3 beta-ol, alpha-spinasterol 3-o-beta-d-glucopyranoside, stigmast-7-en-3 beta-ol 3-o-beta-d-glucopyranoside and vanillic acid. on the basis of the results of spectral and chemical investigations, these glycosides were characterized as 25-o-beta-d-glucopyranosyl-11-oxocucurbit-5-ene-3 beta,24( ...	2009	2760812
the effect of subminimal inhibitory concentrations of antimicrobial agents on three bacterial mixtures.	a test tube technique was developed to screen bacterial mixtures to detect interbacterial interactions that play a role in determining sensitivity to antimicrobial agents. we found 3 mixtures where these bacterial interactions change the sensitivity to antimicrobials or change the proportions of each bacterial species in the mixture. the mixtures were: fusobacterium nucleatum 102.3 and bacteroides endodontalis atcc 35406; f. nucleatum 102.3 and b. endodontalis bn11 a-f; and capnocytophaga ochrac ...	1989	2762019
[amborum special f and asfo--2 glucocorticoid-containing herbal remedies].	amborum special f and asfo are two names of a herbal remedy which is adulterated with the glucocorticoid betamethasone. patients with asthma, rheumatic and chronic diseases import the drug direct from burbank, california, usa. its impressive antiasthmatic effect is reported in two patients. while under therapy the first patient developed cushing's syndrome and the second showed suppression of adrenal cortisol production. the manufacturer, who claims that the drug contains no "western medicine" a ...	2009	2762789
[legal foundation and practical execution of slaughtering and meat examination of game animals].	meat regulations also involve game inspection. on the one hand the previous publications dealt with the regulations and their practice concerning game intended for slaughter, especially the control of fences and the gaining of meat. on the other hand regulations concerning game hunted for food (deer: red deer, sika deer, fallow deer, roe deer; horned ungulates: european mufflon, chamois; wild boar; european hare; european rabbit; game such as badger and raccoon) and regulations to be observed by ...	1989	2763282
preservation of gabaergic perikarya and boutons after transient ischemia in the gerbil hippocampal ca1 field.	using an antibody directed against the gamma-aminobutyric acid (gaba)-synthetizing enzyme glutamate decarboxylase (gad) the fate of the gabaergic innervation was investigated in the hippocampal field ca1 of gerbils up to 14 days after a bilateral transient 5-min occlusion of carotid arteries. as described previously, the ca1 pyramidal cells were subject to the ischemia-induced delayed neuronal death, the first signs of which were detectable after 2 days and which was fully developed after 4 days ...	2009	2765929
in vivo clearance studies of the terminal fluid-phase complement complex in rabbits.	the present study was directed at obtaining information on the in vivo elimination rate of sc5b-9, the terminal fluid-phase product of complement activation. a sandwich elisa based on the use of mono- and polyclonal antibodies was constructed that permitted quantitation of rabbit sc5b-9 in plasma. rabbit serum was activated with inulin in vitro to generate sc5b-9, and the activated serum was applied intravenously in normal and c6-deficient rabbits. elimination of sc5b-9 in normal rabbits was rap ...	1989	2766574
the microbiota of early periodontitis lesions in adults.	the predominant cultivable microbiota of shallow progressive (active) periodontal lesions in 4 adults (29-40 years) was compared to that of shallow inactive sites. periodontal attachment levels were monitored longitudinally, and sites showing 2-3 mm attachment loss in the previous 1-2 months were considered disease active. inactive sites showed no change in attachment level. the microbiota of shallow sites was dominated by gram negative rod species including wolinella recta, bacteroides forsythu ...	1989	2768541
levels of adult alcohol consumption induced by interactions with child confederates exhibiting normal versus externalizing behaviors.	investigated levels of distress and alcohol consumption in ss interacting with problematic vs non-problematic child confederates. social drinkers were randomly assigned to interact with boys trained to enact behaviors characteristic of either normal or attention-deficit disorder/conduct disorder (add/cd) children. mood data were collected before and after the interaction. ss engaged in ad lib beer consumption for 20 min, while anticipating another interaction with the same boy. children in the a ...	2009	2768665
accuracy of the subrenal capsule xenograft assay in predicting the clinical growth and chemosensitivity of human squamous head and neck carcinomas.	thirty-seven of 54 human squamous head and neck carcinomas were successfully grown as first transplant generation xenografts under the kidney capsule of conventional mice immunosuppressed by daily treatment with 60 mg/kg of cyclosporine. of the 18 different tumors evaluated for chemosensitivity, 39% responded to cis-platinum, 19% to 5-fluorouracil, 33% to methotrexate, and 40% to cis-pt/5fu. in comparing the assay results in nine patients who received the same chemotherapeutic drugs, two of thre ...	1989	2770306