acupuncture: its neurophysiological basis: an anaesthetist's foreword. 197829773
anaerobic pulmonary infections.the main cause of anaerobic pulmonary infections is aspiration of saliva, upper airway secretions or gastric content. predisposing conditions include prominent dental disease, chronic upper respiratory tract infections and reduced consciousness. fusobacterium nucleatum, bacteroides melaninogenicus and anaerobic gram-positive cocci are the most frequently encountered organisms. the clinical presentations are lung abscess, lung gangrene and empyema, which all tend to take a slow and indolent cours ...197937594
the effect of mixed phosphatidylcholine liposomes on beef heart cytochrome c oxidase [proceedings]. 197884573
cross-reaction between the mycelial galactomannas of three hormodendrum strains and the mannans of two candida albicans strains of different serotypes, a and b.cross-reactivity between galactomannans of three representative hormodendrum strains, h. pedrosoi ifo 6071, h. compactum ifo 6726, and h. dermatitidis ifo 6421, and the mannans of two candida strains, c. albicans nih a-207 (serotype a) and c. albicans nih b-792 (serotype b), were investigated by means of agar-gel double diffusion, quantitative preciptin reaction, and passive cutaneous anaphylaxis. the following results were obtained. (i) antisera to whole cells of three hormodendrum strains were ...197984792
the allergenic structure of allergen m from cod. iii. studies on the antigenicity of long-sequence peptides.fragments tm 1 (75 amino acid residues) and tm 2 (38 amino acid residues), and 3 other polypeptides (range 16-25 amino acid residues) of allergen m from cod were shown to be active in rabbit igg-mediated reactions. the same peptides were previously found to possess reactivity in ige-mediated reactions, thus suggesting a structural relationship between their antigenic and allergenic determinants.197984803
localization of nors in chromosomes of mouse cell lines by a combined 33258-hoechst and ag-staining technique. 197984805
solid phase indirect radioimmunoassays for the rapid diagnosis of sindbis virus antigen.indirect radioimmunoassays have been developed for the rapid detection of sindbis virus. dilutions of sindbis virus from tissue culture fluids have been immobilized and allowed to react with rabbit anti-sindbis virus antibodies. the bound antibodies were assayed either by 125i-labelled anti-rabbit igg-antibodies or alternatively by addition of human complement and 125i-labelled anti-human c1q antibodies or 125i-labelled protein a.197884855
immunochemical characterization of the plasmin-antiplasmin system. basis for the specific detection of the plasmin-antiplasmin complex by latex agglutination assays. 197985679
[intratypical antigenic differentiation of poliovirus strains circulating in mali by means of cross-adsorbed sera].the intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in mali in 1975-1976 was performed. the method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. all the examined strains of serologic types i, ii, and iii were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". quantitative differences in the ant ...197886237
mutagenicity in urine of nurses handling cytostatic drugs. 197987722
[the antibacterial action on dental plaque of antibiotics used in dentistry. 2. in vitro experiments on streptococcus mutans, staphylococcus aureus and fusobacterium nucleatum (author's transl)]. 197788239
prostaglandin e1-induced latent epileptogenic foci.suprafusion of 125 microliter 6% kcl solution over the visual cortex of rabbits 2-24 h after they suffered a prostaglandin (pg) e1-induced epileptic seizure was found to cause a recurrence of seizure activity. the initial seizure was induced by the cortical suprafusion of pge1 over the left visual cortex of pg transport inhibitor-pretreated rabbits. control animals that were not pretreated with pg transport inhibitors (bromcresol green or probenecid), or received suprafusion of saline or pgf2 al ...197988324
resistant vibrio cholerae el tor in tanzania. 197988577
[post-extrasystolic and post-pacing potentiation. ii. study by means of systolic time intervals in man]. 197888948
cea-like antigens in different histologic types of human lung carcinoma.comparative studies on the presence and immunological reactivity of cea and cea-like antigens in lung and digestive tract cancers were performed. specific goat and rabbit anti-cea immune sera were used. immunofluorescence studies revealed in histologically different types of the lung carcinomas the presence of the cross reacting antigen with classical cea. absorption procedures, and double diffusion tests have shown the existence of two at least antigenic determinants in cea molecule: 1. the det ...197989630
distribution of myosin isoenzymes among skeletal muscle fiber types.using an immunocytochemical approach, we have demonstrated a preferential distribution of myosin isoenzymes with respect to the pattern of fiber types in skeletal muscles of the rat. in an earlier study, we had shown that fluorescein-labeled antibody against "white" myosin from the chicken pectoralis stained all the white, intermediate and about half the red fibers of the rat diaphragm, a fast-twitch muscle (gauthier and lowey, 1977). we have now extended this study to include antibodies prepare ...197990047
effects of arachidonic acid and its metabolites on antigen-induced histamine release from human basophils in vitro. 197990097
polyribonucleotide inhibition of ribonucleic acid directed deoxyribonucleic acid polymerase of mouse mammary tumor (type b) virus and simian sarcoma (type c) virus. 197990331
the elephant man. 197990342
the expression of a human b-lymphocyte antigen and surface membrane immunoglobulin by lymphoid cells from patients with lymphocytic lymphoma, multiple myeloma and benign monoclonal gammapathy. 197990449
the indirect rat mast cell degranulation test reconsidered.the indirect rat mast cell degranulation test for the detection of human reaginic antibodies was reinvestigated. when the mast cells were incubated with human reaginic serum at concentrations exceeding approximately 3%, a massive, non-specific histamine release occurred, irrespective of the presence or absence of allergen. at tolerated serum concentrations (below 3%), the allergen concentration did not influence the release process. we conclude that the indirect rat mast cell test is not applica ...197990655
antigen-specific suppressor factors produced by t cell hybridomas for delayed-type hypersensitivity.this study describes the generation of t hybridoma lines which secret factors specifically suppressing delayed-type hypersensitivity (dth) to sheep red blood cells (srbc). akr strain-derived t lymphoma bw 5147 cells were fused with spleen cells from mice primed with srbc and containing antigen-specific t suppressor cells for dth. supernants from the derived hybridomas were tested for suppression of either expression of induction of dth to srbc. six lines produced specific suppressor activity for ...197991526
application of human erythrocytes to a radioimmune assay of immune complexes in serum. 197991576
epithelioid sarcoma: ultrastructural observation of lymphoid cell-induced lysis of tumor cells.epithelioid sarcoma of the palm of 7 months' duration was observed in a 30-year-old man. six months after wide surgical excision there was no evidence of recurrence or metastasis. by light microscopic examination the tumor showed typical nodular arrangement of malignant cells, with necrosis of these cells in the centers of the nodules. patchy lymphocytic infiltrates were observed at the peripheries of the nodules and also extended in places between the tumor cells. other types of inflammatory ce ...197992147
intracellular distribution of dopa and 5-s-cysteinyldopa in pigment cells with minimal pigment formation.the hypothesis that only melanosomal catecholic amino acids contribute to melanin formation was tested by studying adult bovine eyes in which pigment synthesis is considered to be low or absent. dopa and 5-s-cysteinyldopa were investigated in different cell fractions of the choroid and retinal pigment epithelium of cattle. most of the dopa and 5-s-cysteinyldopa was found in the cytoplasm and very little in the large granule fraction. the presence of cysteinyldopa in the adult eye is evidence of ...197992151
membrane-bound mitochondrial dna: isolation, transcription and protein composition.mitochondrial membrane-bound dna complex from bovine heart mitochondria lysed in the presence of triton x-100 was isolated by differential centrifugation. the yield of "nucleoid" is about 30 microgram protein/mg mitochondrial protein. it contains about 3-5 microgram dna/mg protein and varying amounts of rna. the heart mitochondrial nucleoid actively synthesizes rna. the nucleoid fraction contains about sixteen different proteins as evidenced by urea-sds gel electrophoresis and about twenty-one p ...197992288
post-burn changes in basic biochemical indices in rat liver tissue. 197992875
o-antigenic cross-reactivity in fusobacterium nucleatum.lipopolysaccharides (lps) of the same chemotype isolated from seven strains of fusobacterium nucleatum were examined by indirect haemagglutination and inhibition of haemagglutination in unabsorbed and absorbed antisera. four common major antigenic specificities were detected, and two of the lps examined contained antigenic specificities not shared with any of the other lps. in addition, a few weak cross-reactions were observed, also with some lps of other chemotypes.197994236
effect of 6-hydroxydopamine on baroreceptor-heart rate and nasopharyngeal reflexes of the rabbit. 197994399
mechanism of binding of mouse interferon to controlled pore glass.many proteins bind to controlled pore glass; they are either acid elutable or alkali elutable. mouse interferon is an acid-elutable protein. since poly(l-lysine) and, to some extent, poly(l-arginine) are also eluted from controlled pore glass under acidic conditions, one may postulate that mouse interferon binds to controlled pore glass via some of the protein's epsilon-amino groups (of lysine) and/or guanidinium groups (of arginine) and the beads' silanol (hydroxyl groups). the necessity of lys ...197994835
analysis of anti-sperm sera for t/t locus-specific objective antiglobulin radioimmunoassay for the analysis of anti-spermatozoa antisera has been used to characterize more than 30 alloantisera. each of these antisera was raised against spermatozoa from mice carrying t/t regin mutations. whilst all of the antisera had considerable activity for mouse spermatozoa, none of them was found to contain antibodies specific for t/t region gene products. a detailed analysis of a single serum revealed that its activity is for antigens which are non-polym ...197995255
bacillus subtilis 168 genetic transformation mediated by outgrowing spores: necessity for cell contact.transforming activity released in sequential genetic order during the first synchronous cycle of dna replication during outgrowth of spores of bacillus subtilis 168 was investigated. a transformation assay was used consisting of outgrowing spores as dna donors and multiply marked competent cells as recipients. dna synthesis inhibitors known to stop dna release were used during and subsequent to dna transfer to recipient cells. the released dna sedimented with the outgrowing cells after low-speed ...197896105
polarized light retinal photography of a monkey eye. 197896590
effect of oophorectomy on estrogen receptors in rat mammary tumors induced by 7,12-dimethylbenz (a)anthracene. 197796813
sugar inhibition of oral fusobacterium nucleatum haemagglutination and cell binding. 197944185
[suprachiasmatic nucleus, an hypothalamic regulation center of vital rhythmic functions]. 197897067
regulation of the rate of beta-galactosidase synthese by the bgs and bgt loci in the mouse.we have developed an assay for the in vivo rate of beta-galactosidase synthesis in mouse tissues to assess the mechanism by which the bgs and bgt loci regulate activity levels of this enzyme. genetically determined differences in liver and kidney beta-galactosidase content reflect equivalent differences in specific rates of enzyme synthesis. we conclude that bgs and bgt regulate beta-galactosidase activity by controlling the rate of synthesis of the beta-galactosidase molecule.197897289
[intracellular oxygen and the radiosensitization of cells of the blue-green alaga, anacystis nidulans].the photosynthetic system of the blue-green alga anacystis nidulans was inactivated by 30% at a dose of 100 krad of gamma irradiation in n2. if the cells were irradiated in n2+2% co2 in the light, their radiation sensitivity was increased with an oxygen enhancement ratio of 2.0. neither light nor co2 taken separately affected radiosensitization of the cells which increased almost to the same extent as under aerobic conditions in the presence of both light and co2. the intracellular oxygen of the ...197897503
effect of low temperature on growth, viability, and synthesis of mycolic acids of mycobacterium tuberculosis strain h37ra.cultures of mycobacterium tuberculosis strain h37ra were grownto early logarithmic phase at 37 degrees c and were incubated at 16 degrees, 20 degrees, and 25 degrees c. the decrease in this ability was more rapid at 20 degrees c than at 16 degrees c. low-temperature incubation caused decreases in the ratios of mycolic acids and monounsaturated c16-19 fatty acids relative to the total of fatty acids synthesized. it also caused an increase in the ratio of saturated c24-26 fatty acids relative to ...197898081
trh-like immunoreactivity in urine, serum and extrahypothalamic brain: non-identity with synthetic pyroglu-hist-pro-nh2 (trh).trh-like immunoreactive substances obtained from several areas of rat brain and from human serum and urine were chromatographically separated by tlc and the resulting immunoreactive 'elution profiles' compared with that obtained for pyroglu-hist-pro-nh2 (trh). for hypothalamus and septal-preoptic samples trh was present, but represented less than 100% of the immunoreactive substances. for cortex, amygdala, brain stem, serum and urine, no trh was detectable in the immunoreactive substances from t ...197898209
quantitative electron microscopic studies of the changes in rat hepatocytes following halothane induced anaesthesia. 197798410
[clinical, parasitological and serological investigations in sarcosporidiosis (sarcocystis suihominis) of man (author's transl)].eight medical students ate for a test raw meat from a pig experimentally infected with sporocysts of sarcocystis suihominis. the meat had been officially controlled before and was found free of trichinella and qualified for consumption. 6 to 24 hours after the meal all persons suffered from acute clinical symptoms, above all diarrhoea and vomiting, coldness and sweating which decreased, however, within 12 to 24 hours. clinical-chemical investigations made during this time suggested an acute infe ...197898426
freedom, the will-o'-the-wisp. 197898690
quantitation of particles in the freeze-fractured nuclear membrane after renal ischemia.changes in the number and sizes of membrane-associated particles have been quantitated in the protoplasmic (p) and exoplasmic (e) fracture faces of the outer membrane of nuclei isolated from the inner cortex following renal ischemia and reflow in the rat. no changes were observed in the inner nuclear membrane. after 20-min ischemia, the number of particles in both fracture faces decreased. with reflow, the total number of particles decreased after both 20- and 60-min ischemia. the partition coef ...197898907
[measurement of the variations of cytoplasmic and nuclear volumes of the absorbing cells of the digestive tube according to the nutritional conditions, in the larva of the common toad (bufo bufo l.)]. 197898945
jaundice and breast-feeding among alaskan eskimo newborns.the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ...197899026
[cannabis].cannabis produces a resin, the psychotropic effects of which are known since the high antiquity. it induces euphoria, a feeling of pleasant dreaminess. nevertheless, psychiatric disturbances such as psychomotor deficiency states or acute oniroïd states were described in heavy users countries. these psychiatric disorders put the accent on the starting or catalysing role of cannabis on the premorbid personality. the experimental studies of cannabis on the premorbid personality. the experimental st ...1978100034
[epidemiological study on beta hemolytic streptococci among healthy school children in toda city, saitama (author's transl)]. 1978101618
appearance of histochemically detectable ionic calcium in degenerating primary sensory neurons.the effect of neonatal capsaicin treatment on the fine structure and localization of ionic calcium in sensory ganglion cells has been investigated in rats. neonatal capsaicin treatment resulted in the degeneration of certain type b sensory neurons. at the same time ionic calcium was demonstrated histochemically in the perikarya of numerous small-sized ganglion cells. the appearance of histochemically detectable ionic calcium in these cells in relation to the pharmacologically evoked degeneration ...1978104522
serologic reactions of oral gram negative anaerobic bacilli.serological reactions were performed using hyperimmune rabbit antisera and antigenic preparations of leptotrichia buccalis, fusobacterium fusiforme, and fusobacterium polymorphum. all tests indicated that there was serologic cross reactivity between the two fusobacterium species. no cross reactivity could be detected between the fusobacterium species and l. buccalis. the findings suggest that f. fusiform and f. polymorphum are similar in their immunogenicity, and that the grouping of these two o ...1979105024
[effect of polychlorinated biphenyls in the rat: ii.--preliminary report on metabolic alterations (author's transl)].rats were fed with a diet containing 10 and 100 ppm (wet weight) of phenoclor dpr for 4 weeks in order to evaluate the toxicity of a french pcb mixture. the influence of pcb was studied by determining the liver weights, the hepatic and muscular proteins, glycogen and humidity content as well as hematocrite, glucose, proteins and lipids in the plasma, and the lipidic contents of the liver and the carcass. there was a significant increase in both liver to body weight ratios and liver lipid and pro ...1978105425
membrane changes during growth of tetrahymena in the presence of ethanol.after a brief lag period for acclimation, tetrahymena pyriformis, strain nt-1, is capable of growing in culture medium containing high levels of ethanol. when grown in a medium having 1.6% ethanol, the membrane phospholipid composition was significantly different from that of control cells. the principal changes included a reduction in hexadecenoic acids (16 : 1 and 16 : 2) from 23% to 5% and an increase in linoleic acid (18 : 2) from 14% to 25% similar but less pronounced changes were observed ...1979105757
sensitivity of pseudomonas aeruginosa envelope mutants to alkylbenzyldimethylammonium chlorides.a series of stepwise polymyxin-resistant envelope mutants of pseudomonas aeruginosa was used to test the activity of a homologous series (c10-c18) of alkylbenzyldimethylammonium chlorides. a sterilization kinetics procedure in deionized water was devised to avoid amounts quaternary compound above the critical micelle concentration. in all cases, there was a linear relationship between the logarithm of the rate of change of the colony count with time and the logarithm of the homolog concentration ...1979106105
betamethasone and the rhesus fetus: multisystemic this controlled study of betamethasone administration to pregnant rhesus monkeys, using dosages per gram of fetal body weight similar to those reported in several human clinical studies, the most significant fetal pulmonary changes observed were increases in maximum lung volumes. the fact that comparable increases in peak volumes were demonstrated on saline filling supports our contention that these changes are related primarily to lung structural alterations rather than surfactant effects. a ...1979106730
ultrastructural localisation of lipopolysaccharide-binding sites with peroxidase-conjugated lipopolysaccharides.the localisation of lipopolysaccharide-binding sites on erythrocytes with peroxidase-coupled lps is described. lps was isolated from fusobacterium nucleatum (fus mc-8) by phenol-water extraction. the lps was coupled to horseradish peroxidase by the two-step method of avrameas and ternynck (1971). the biological and serological activities of the conjugated lps were compared with those of the native material. peroxidase could be coupled to lps without significant loss of endotoxic or serological a ...1979107240
extravasation of albumin in tissues of normal and septic baboons and sheep. 1979107367
properties of the bacillus subtilis spore coat.about 70% of the protein in isolated bacillus subtilis spore coats was solubilized by treatment with a combination of reducing and denaturing agents at alkaline ph. the residue, consisting primarily of protein, was insoluble in a variety of reagents. the soluble proteins were resolved into at least seven bands by sodium dodecyl sulfate gel electrophoresis. about one-half of the total was four proteins of 8,000 to 12,000 daltons. these were relatively tyrosine rich, and one was a glycoprotein. th ...1979108242
turnover of protein-bound lipoic acid. 1979108509
organ culture model for the study of hvh-ii infections in carcinoma of the experimental model is described whereby human and monkey cervical tissues may be maintained as organ cultures for 21 and 40 days, respectively. inclusion of sodium carboxymethyl cellulose in the culture medium prolongs the survival time of tissues considerably. the sequential cytologic changes associated with herpesvirus hominis type ii (hvh-ii) infection are reported. these changes are considered in relation to the possible causal role of hvh-ii infection in cervical carcinogenesis.1979108642
[prevention of sequelae after transcutaneous radiotherapy for epitheliomas of the oral cavity (author's transl)].close cooperation between the radiotherapist, surgeon, and patient is necessary in order to prevent sequelae following transcutaneous radiotherapy for epitheliomas of the oral cavity. the most effective therapeutic results combined with a minimum of sequelae are obtained by the use of a good irradiation technique, close supervision, careful treatment of any oral or dental affection, prescribing simple medications only, and stopping the use of tobacco and alcohol.1979111344
haemagglutination inhibition and aggregation of fusobacterium nucleatum by human salivary mucinous glycoproteins. 1979120169
methionine transport in pseudomonas aeruginosa.a high-affinity (km = 2.7 x 10(-7) m) energy-requiring methionine-transport system has been characterized in rm 46 and rm 48, two different pao methionine auxotrophs of pseudomonas aeruginosa. after 8 s of transport 40--60% of the methionine label in the alcohol extract appears in s-adenosyl-l-methionine (sam) with the remaining activity in free methionine. methionine transport required a high degree of structural specificity for transport. stimulation of transport occurred by addition of glucos ...1979120222
health effects of the gas-aerosol complex. report to special committee on health and ecological effects of increased coal utilization.combustion products derived from the burning of coal are definitely capable of producing adverse human health effects. no single component of the combustion product mixture is solely responsible. rather, effects are due to a group of compounds, both gases and aerosols, in the effluents of stationary source combustion processes. although incompletely defined, the individual components of the gas-aerosol complex appear to be capable of interacting both in terms of atmospheric chemistry and health ...1979120252
human complement activation by lipopolysaccharides from bacteroides oralis, fusobacterium nucleatum, and veillonella parvula.the properties of different lipopolysaccharide (lps) preparations to induce c3 conversion in human serum was studied by means of crossed immunoelectrophoresis. c3 conversion by the alternative pathway was evaluated after calcium depletion, and lipid a-dependent activation was measured by means of inhibition with polymyxin b sulfate. lps from bacteroides oralis converted co mainly via the alternative pathway, whereas lps from fusobacterium nucleatum and veillonella parvula const pronounced lipid ...1979121108
structural studies of heparitin sulfates.heparitin sulfate fractions with a large range in sulfate content were subjected to degradation by flavobacterium heparinase and by nitrous acid. the products obtained were fractionated by chromatography, characterized, and used to arrive at tentative structures for these complex polysaccharides. the heparitin sulfate chains examined appear to be composed of: 1. uninterrupted blocks of n-acetylglucosamine containing disaccharides; 2. larger blocks with a molecular weight range of 5000 to 6000 wh ...1975123778
external velour dacron grafts in renal artery reconstruction.aortorenal interposition grafts were performed in dogs using a new external velour knitted dacron graft. encapsulation and endothelialization of these grafts occurs as early as two weeks postoperatively. complete healing is seen by six weeks, and the cellular lining of these grafts appears to be continuous with, and histologically similar to, the endothelium of contiguous arteries. the healed nonthrombogenic characteristics of this graft material represents a considerable improvement over graft ...1975124104
rate and time of dna synthesis of individual chinese hamster cells.the duration of dna synthesis of a diploid cell line of chinese hamster fibroblasts was determined in a comparative study by the flm technique, and also by a new technique for measuring the rate of dna synthesis of individual cells. these methods produced comparable results when applied during exponential growth of the cells. the rate of dna synthesis was measured by means of quantitative autoradiography following a short-term incubation of the cells with 5 x 10(-6) m fudr and 10(-5) m 14c-tdr. ...1975126804
calcium uptake and atpase activity of microsomes from heterotopically transplanted rabbit heart.heterotopic cardiac transplantation was performed in rabbits. the calcium uptake and atpase activities of microsomal fraction were studied in three groups (group i, normal controls; group ii, early transplants; group iii, late transplants) during severe rejection as characterized histologically and electrocardiographically. group iii showed a significant decrease in calcium uptake but no difference in atpase activity compared with groups i or ii. the results demonstrate that in the rejecting tra ...1975127353
biologic activity of soluble collagen-anticollagen immune complexes as demonstrated by passive cutaneous anaphylaxis.collagen-anticollagen immune complexes were prepared by gel filtration. complex formation was chemically and serologically demonstrated. complexes eluting in gammam- and gammag-peaks of antigen-antiserum mixture showed strong positive reactions in pca experiments performed with 20 guinea pigs. control preparations of gammam- and gammag-peaks of antiserum devoid of antigen gave significantly lower pca-response. the positive reaction of control preparations can be explained in part by a certain de ...1975127469
histoenzymatic changes in liver in acute poisoning with furfural. 1975127937
cell number in human heart in atrophy, hypertrophy, and under the influence of cytostatics.the dna content was determined in 30 human hearts from different age groups and of different weight classes. among these cases were included 4 hearts of children and 5 hearts of adults who had been treated with cytostatics. the total dna content was determined biochemically and the nuclear dna content was measured by means of feulgen cytophotometry. by combining both methods, the total number of heart muscle cells was determined. we obtained the following results: (1) the dna concentration remai ...1975128080
total viable count and differential count of vibrio (campylobacter) sputorum, fusobacterium nucleatum, selenomonas sputigena, bacteroides ochraceus and veillonella in the inflamed and non inflamed human gingival crevice. 1975129552
dynamics of sulfonylurea-induced insulin release from the isolated perfused rat the isolated perfused rat pancreas various sulfonylurea drugs were tested with a basal glucose level of 1 mg/ml in the perfusion buffer and were found to cause a biphasic insulin response. novocs 476, a new and potent sulfonylurea, and glibenclamide qualitatively differed from tolbutamide, glibornuride, glipizide, and glisoxepide, which were all alike in terms of the relationship between first and second phases of insulin release.1976134920
the metabolic effects and uptake of ethidium bromide by rat liver mitochondria. 1977141908
the anticomplementary activity of lipopolysaccharide preparations and sonicates from a strain of fusobacterium nucleatum. 1978147329
experimental spongy degeneration of the white matter induced by 6-aminonicotinamide intoxication.spongy state and degeneration of the white matter in the 6-aminonicotinamide intoxicated rats were studied neuropathologically and electromicroscopically. young albino rats, four weeks of age, received 0.1% of 6-aminonicotinamide solution intraperitoneally as a single dose of 10 mg/kg of body weight. four hours after the administration, paralysis of the hind limbs occurred in the rats. neuropathological investigations revealed a characteristic spongy and degenerative change of white matter as we ...1978149717
effect of human immunoglobulin preparations on fc rosette formation between anti-d-coated erythrocytes and lymphocytes.human immunoglobulin (ig) preparations were tested for their inhibitory effect on fc rosette formation between anti-d-coated human erythrocytes and lymphocytes, as compared to their complement activating capacity. both of the two biological activities ascribed to the sites in the fc portion of the igg molecules were found to be reduced in the pepsin-treated, as well as in the s-sulfonated ig preparations, as compared to the activities of the normal human ig preparation. in the plasmin-treated ig ...1978150144
[new species of obligate-thermophilic bacteria of the flavobacterium thermophilum type]. 1978154607
subcellular effects of some anesthetic agents on rat myocardium.the effects of ether, chloroform, and halothane on calcium accumulation and atpase activity of rat heart microsomes and mitochondria as well as on myofibrillar atpase activity were investigated. chloroform and halothane depressed microsomal and mitochondrial calcium uptake and binding in a parallel fashion. ether decreased microsomal calcium binding and mitochondrial calcium uptake to varying degrees, while mitochondrial calcium binding was slightly enhanced. whereas ether had no effect, chlorof ...1979154965
neurotoxicity of acrylamide and its analogues and effects of these analogues and other agents on acrylamide neuropathy.n-hydroxymethylacrylamide, n-methylacrylamide, and n,n-diethylacrylamide produce peripheral neuropathy in rats. seven other compounds related to acrylamide do not produce neuropathy. rats given one of the three neurotoxic compounds are more susceptible to acrylamide. a regime for testing acrylamide analogues for neuro-toxicity is suggested. ddt, phenobarbitone, or high dietary concentrations of vitamin a or e have no effect on the development of acrylamide neuropathy in rats. acrylamide produces ...1975164879
induction of autophagic vacuoles in peritoneal cells. 1975165296
letter: petechiae: due to adenovirus type 7 infection or to acetylsalicylic acid therapy? 1975165451
letter: light induced change in rod outer segment membrane fluidity. 1975165628
veterinary aspects of salmonid fish farming: husbandry diseases.most disease problems affecting farmed salmonid fish are either caused or exacerbated by bad husbandry and poor environmental conditions. the aspects of water quality and nutrition which are significant in causing husbandry problems are considered. the clinical aspects of these diseases are decribed in terms of the life cycle of salmonids, and methods of prevention are discussed.1975168680
structural studies on two adenovirus 2-sv40 hybrids containing the entire sv40 genome. 1975169085
an outbreak of infectious bursal disease (ibd) of chickens in nigeria. 1975175539
steroid production by quartered and capsular rat adrenal gland in response to haemorrhage.60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ...1975179800
genital herpetic infection in men and women: clinical course and effect of topical application of adenine arabinoside.sixty-three episodes of genital herpetic infection in 55 men and 45 episodes in 42 women were randomly assigned to topical treatment with 3% adenine arabinoside, topical treatment with placebo ointment, or no therapy. in addition, 10 episodes in women who were not randomly assigned to therapy were evaluated and followed. clinical evaluation and viral cultures were done on day 3, day 8, and weekly thereafter until the lesions had healed. the natural clinical course of genital herpetic infection w ...1976180196
effectiveness of orally administered bordetella pertussis vaccine in mice.oral administration of killed bordetella pertussis organisms to mice results in increased resistance to an intracerebral infection with virulent b. pertussis cells. the rate of survival is dependent on the dose of antigen. but besides specific systemic immunity, which is persistent over a long period, also transient non-specific resistance is increased. these effects are evidently induced without penetration of bacterial substances into the circulation.1976182602
inflammatory cells in solid murine neoplasms. i. tumor disaggregation and identification of constituent inflammatory cells.mechanical and enzymatic methods of disaggregating tumors were studied with the goals of (1) minimizing cell losses while (2) maintaining functional and surface membrane markers needed to objectively identify inflammatory cells (ic)1 in resultant suspensions. application of the principles and methods described makes accurate estimation of the percentage of each ic type present in neoplasms possible for the first time. compared to purely mechanical means of disaggregating tumors, all enzyme mixtu ...1976182647
the effect of hypoxia on collagen synthesis in cultured 3t6 fibroblasts and its relationship to the mode of action of ascorbate.when exposed to low oxygen tension, in the absence of added ascorbic acid 3t6 mouse fibroblast cultures in late log phase respond by increased lactate production and increased hydroxylation of proline in nascent collagen, which is paralleled by an increase in prolyl hydroxylase activity. after 6 h recovery from the anoxic stimulus, however, cultures still yield more prolyl hydroxylase than controls, but the effect on hydroxylation of nascent collagen has disappeared. these observations help to d ...1976183826
study of the properties of different strains of avian encephalomyelitis virus. 1976187531
regulation of norepinephrine release from cardiac sympathetic fibers in the dog by presynaptic alpha- and beta-receptors.the effect of phenoxybenzamine (pba), desmethylimipramine (dmi), clonidine (clnd), sotalol (stl), and isoproterenol (ispr) on the release of endogenous norepinephrine (ne) from the heart on right cardioaccelerator nerve stimulation was studied in anesthetized dogs. under control conditions, the catecholamine levels in coronary sinus blood increased linearly with increasing frequencies of stimulation up to 10 hz and did not increase further at 30 hz. the release of ne was markedly enhanced after ...1977193655
adenovirus of ring-necked pheasants: purification and partial characterization of marble spleen disease virus.a method for purification of marble spleen disease virus (msdv) from the spleens of infected turkeys and pheasants is described. it combines chloroform or fluorocarbon extraction with subsequent purification by centrifugation on a cushion of cesium chloride (cscl). further purification of msdv was accomplished with a cscl equilibrium density gradient. a viral buoyant density of approximately 1.32 to 1.33 g/cm3 was determined. negative-stain electron microscopy revealed that virus isopycnically b ...1977193796
on the mode of action of clonidine: relationship between effects on behaviour and cyclic nucleotide content in mouse brain. 1977196226
comparison of interferon action in interferon resistant and sensitive l1210 cells.translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...1978212514
purification and properties of hydrogenase from clostridium pasteurianum. 1978213683
pathogenesis of infectious mononucleosis, burkitt's lymphoma and nasopharyngeal carcinoma: a unified scheme. 1978221392
comparison of immune responses and viral markers in herpesviruses-associated carcinomas: a review. 1978221405
secretory granules of the duodenal enterochromaffin cells of the cat. 1979222959
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