| anaerobic (putrid) lung abscess in adolescence. | two adolescents with acute anaerobic (putrid) lung abscess were seen during an influenza epidemic. one patient, who had a history of seizures and a dental infection, had a classic predisposition to this disease. in the second patient, the abscess was apparently acquired as a complication of influenza. in both cases, the preliminary diagnosis was staphylococcal pneumonia with pneumatocele. it is suggested that failure to consider an anaerobic cause in pulmonary infections, inappropriate specimens ... | 1976 | 813518 |
| microbial synergy in experimental intra-abdominal abscess. | intra-abdominal sepsis was studied in wistar rats by using four microbial species: escherichia coli, enterococci, bacteroides fragilis, and fusobacterium varium. these organisms were implanted into the peritoneal cavity singly and in all possible dual combinations. results were evaluated by mortality rates and the incidence of intra-abdominal abscesses on autopsy following sacrifice after 7 days. mortality was restricted to recipients of e. coli, thus implicating coliforms in the acute lethality ... | 1976 | 814099 |
| antimicrobial therapy of anaerobic infections. | | 1975 | 1041514 |
| effect of sonic treatment on pure cultures and aggregates of bacteria. | pure cultures of a variety of bacteria were treated with ultrasonic energy using a sonic probe. fractions of organisms killed at different sonic energies were calculated, and streptococcus mutans was 600 times more resistant than fusobacterium nucleatum, the most sensitive organism tested. the effects of sonic treatment on aggregates of bacteria were examined, and the results were interpreted as a model of the events that probably occur during the sonic dispersion of dental plaque. | 1976 | 819454 |
| antibiotic treatment of oral anaerobic infections. | | 1975 | 1056466 |
| the predominant cultivable organisms in juvenile periodontitis. | quantitative and qualitative examinations of the predominant cultivable microflora of the advanced tissue destruction (pocket) associated with juvenile periodontitis and of control pockets without loss of attachment were carried out by using anaerobic tube culture technique. the microflora from the control sites consisted primarily of streptococci, gram-negative rods, and gram-positive rods. in contrast, the test pockets had a relatively stable and characteristic microflora, dominated by various ... | 1976 | 1061986 |
| 12alpha- and 7alpha-hydroxysteroid dehydrogenase activities from fusobacterium spp. | on screening fecal organisms for hydroxysteroid dehydrogenase activities applicable to bile acid metabolism studies, we have isolated a gram negative "bacteroides-like" anaerobe which yields both 12alpha- and 7alpha-hydroxysteroid dehydrogenase (hsdh) activities in cell-free preparation. at the optimal harvest time of 36 hours, approximately 4500 units 12alpha-hsdh and 360 units 7alpha-hsdh were produced per 10(10) viable cells. the two enzymes appear to be separate entities in the basis of thei ... | 1976 | 829879 |
| immunity in foot-rot infection. | | 1976 | 1063947 |
| soluble antigens of leptotrichia buccalis: their reaction with rabbit antisera. | | 1975 | 1068997 |
| immunoelectron microscopic localization of lipopolysaccharides in the cell wall of bacteroides oralis and fusobacterium nucleatum. | lipopolysaccharides (lps) have been extracted and purified from two anaerobic gram-negative bacteria: bacteroides oralis and tfusobacterium nucleatum. chemical analysis of the preparations showed a great proportion of neutral sugars, mainly glucose, in lps of b. oralis. in rabbits, lps of b. oralis induced both immunoglobulin m and g antibodies in contrast to lps of f. nucleatum, to which only immunoglobulin m antibodies were produced. an immunohistochemical method with horseradish peroxidase-la ... | 1978 | 624589 |
| antimicrobial therapy in ruminants. | | 1975 | 1091078 |
| anaerobic infections of the female genital tract: prospects and perspectives. | | 1975 | 1094357 |
| treatment of anaerobic infections with metronidazole. | the results of treatment of 10 patients with anaerobic infections with metronidazole are presented. six patients were cured, three showed initial good response but circumstances required a change to another drug, and one patient did not respond. the unique spectrum of the drug, its pharmacology, and limitations are discussed. the results indicate that further clinical trials to determine the efficacy of metronidazole in the treatment of anerobic infections are indicated. | 1975 | 1096810 |
| bacterial studies of clindamycin-associated colitis. a preliminary report. | the cause of pseudomembraneous colitis is not known but has been attributed to an alteration in the microbial flora of the colon. to test this hypothesis, a blind, prospective study was undertaken in which fecal samples were cultured quantitatively for aerobic and anaerobic organisms. the patients from which these samples were taken were all receiving clindamycin and had diarrhea secondary to the use of the drug. we were able to show definite differences in the colonic microflora which correlate ... | 1975 | 1097297 |
| chemical structure of the lipid a component of lipopolysaccharides from fusobacterium nucleatum. | the lipid a component of lipopolysaccharides from fusobacterium nucleatum fev 1 consists of beta-1',6-linked d-glucosamine disaccharides, which carry two phosphate groups: one in glycosidic and one in ester linkage. the amino groups of the glucosamine disaccharides are substituted by d-3-hydroxyhexadecanoic acid. the hydroxyl groups of the disaccharide backbone are acylated by tetradecanoic, hexadecanoic, and d-3-hydroxytetradecanoic acids. part of the ester-bound d-3-hydroxytetradecanoic acid i ... | 1977 | 830651 |
| anaerobic specimen transport device. | a device is described and evaluated for the anaerobic transport of clinical specimens. the device limits the amount of oxygen entering with the sample to a maximum of 2%, which is rapidly removed by reacting with hydrogen in the presence of a palladium catalyst. the viability on swabs of 12 species of anaerobes, four strains of facultative anaerobes and a strain of pseudomonas aeruginosa, was maintained during the length of the tests (24 or 48 h). the results demonstrated that this device protec ... | 1975 | 1104656 |
| evaluation of a test kit for identification of anaerobic bacteria. | a test kit for identification of anaerobic bacteria--api--has been compared for accuracy in individual tests and for identification on the genus or species level with pre-reduced anaerobically sterilized media methods on 241 anaerobic strains. the microsystem was found to be reliable and permits identification of the clinically most significance anaerobic bacteria if it is supplemented with other tests such as gaschromatographic analysis, morphology, lecithinase, lipase and antibiotic sensitivit ... | 1975 | 1105128 |
| significance of anaerobic bacteria isolated from the urinary tract. ii. experimental studies. | an attempt to cause retrograde urinary tract infection with bacteroides fragilis (a strain subcultured in artificial media) failed to produce any significant renal infection in rats. intravenous inoculation with fusobacterium (a strain subcultured in artificial media) also did not cause demonstrable renal infection in rats. nor could the anaerobic organism be demonstrated in the kidneys of these animals. animals receiving bacteroides (a strain subcultured in artificial media) inoculated directly ... | 1976 | 1107257 |
| necrobacillosis in deer and pronghorn antelope in saskatchewan. | | 1975 | 1109764 |
| characterization of endotoxin from fusobacterium necrophorun. | endotoxic lipopolysachharide (lps) was obtained from phenol-water extraction of cell walls prepared from mass-cultivated fusobacterium necrophorum. the lps was relatively free of nucleic acids and low in protein, and constituted about 4% of the cell walls. upon acid hydrolysis, some of the components detected were hexosamines (7.0%), neutral and reducing sugars (50.5%), heptose (6.4%), 2-keto-3-deoxyoctonate (0.8%), lipid a (21.0%), and phosphorus (1.7%). under electron microscopy the lps appear ... | 1975 | 1112618 |
| [experience in eradicating necrobacillosis on a state farm]. | | 1975 | 1114669 |
| sensitivity of bacteroidaceae to fosfomycin. | the sensitivity of 116 strains of bacteroides fragilis and 60 strains of sphaerophorus to fosfomycin was studied. of the 178 strains that were tested, 156 were isolated from pathological products in our department and the remainder came from the following collections: nctc, atcc and the institut fur mikrobiologie of the university of bonn. identification was made morphologically and biochemically in accordance with the scheme which we usually employ and which has previously been published. the s ... | 1977 | 832544 |
| effects of fusobacterium necrophorum leukotoxin on rabbit peritoneal macrophages in vitro. | a method to demonstrate leukotoxic activity of fusobacterium necrophorum in vitro is described. continuous dialysis sac culture system, using reduced liquid medium was used to grow f necrophorum for 7-day periods. the continuous culture dialysis filtrate contained leukotoxic substance(s) which appeared to be less than 10,000 in molecular weight, heat resistant, and stable at 4 c for at least 10 days. leukotoxic activity was demonstrated in vitro by determining the percentage of macrophages takin ... | 1977 | 851282 |
| comparative growth rates of selected anaerobic species in four commonly used broth media. | generations times (g(t)) of selected anaerobic species were compared in four culture media commonly used for anaerobic bacteria to evaluate these media for growing inocula for anaerobic antibiotic susceptibility determinations. twenty-two clinical isolates of bacteroides fragilis, fusobacterium spp., clostridium perfringens, and clostridium spp. were tested in schaedler broth, supplemented lombard-dowell broth, supplemented thioglycolate broth, and supplemented peptone-yeast extract-glucose brot ... | 1977 | 856002 |
| disk susceptibility testing of slow-growing anaerobic bacteria. | the susceptibility of 55 strains of slow-growing anaerobes to eight clinically useful or potentially useful antibiotics was determined by agar dilution and disk diffusion tests. strains of the genera peptococcus, peptostreptococcus, megasphaera, veillonella, eubacterium, bifidobacterium, clostridium, and fusobacterium were included. all strains were susceptible to chloramphenicol, but varied in their susceptibility to penicillin, lincomycin, clindamycin, tetracyclines, and vancomycin. correlatio ... | 1975 | 1137353 |
| microdilution technique for antimicrobial susceptibility testing of anaerobic bacteria. | a microdilution technique using commercially available media and materials was developed and used to determine the minimal inhibitory concentrations (mics) of clindamycin, chloramphenicol, tetracycline, minocycline, ampicillin, carbenicillin, cephalothin, and gentamicin for 101 anaerobic isolates. representative strains of bacteroides, clostridium, fusobacterium, peptococcus, and peptostreptococcus were tested. the use of schaedler broth at ph 7.2, an inoculum of 10(5) to 10(7) colony-forming un ... | 1975 | 1137383 |
| susceptibility of sphaerophorus necrophorus isolated from cattle in the sudan to chemotherapeutic agents. | | 1975 | 1139288 |
| a simple method for rapid identification of sphaerophorus necrophorus isolates. | a hemagglutination inhibition test for the rapid identification of sphaerophorus necrophorus is described. erythrocytes from six species of animals were tested and human cells were found to be the best agglutination indicators. antiserum prepared in rabbits was found to be specific for s. necrophorus hemagglutinins when tested against 20 isolates of s. necrophorus and 117 other bacteria belonging to 22 genera. the possibility of using a hemagglutination inhibition test for the detection of bovin ... | 1975 | 1139415 |
| endotoxin from fusobacterium necrophorum of bovine hepatic abscess origin. | the endotoxic activity of fusobacterium necrophorum bov 5 was investigated. the supernatant (s) fluid and cell wall (cw) preparation, obtained after differential centrifugation of the ruptured cell mass, were lethal for mice. the toxicity of the s fluid was stable during prolonged storage, treatment with formalin, and heating for 15 minutes at 80, 100, and 121 c, but was destroyed by alkaline hydrolysis with 0.25 n naoh. the toxic factor was found in a high molecular weight (mw) fraction after g ... | 1975 | 1147341 |
| [in vitro susceptibility of bacteroidaceae to cefoxitin and cephalothin (author's transl)]. | the activity of the new cephamycin c derivatives cefoxitin against 102 clinical isolates of bacteroidaceae (95 bacteroides strains and 7 fusobacterium-sphaerophorus cultures) was determined by tube dilution and standardized agar diffusion tests and compared to that of cephalothin. cefoxitin was more active than cephalothin against 56 bacteroides fragilis strains, 19 bacteroides thetaiota-omicron strains and two bacteroides splanchnicus strains. the difference seemed less pronounced with five bac ... | 1977 | 856727 |
| the effect of temperature on growth and survival of fusobacterium necrophorum isolated from bovine liver abscesses. | the ability of fusobacterium necrophorum to survive or grow in liquid nitrogen or at temperatures between -10 degrees and 59 degrees c was determined. the organism remained viable but did not grow in liquid nitrogen or between -10 degrees and 21 degrees c. it grew between 22 degrees and 43 degrees c. no isolate grew at temperatures above 43 degrees c and all three isolates survived for a minimum of 15 minutes and an average of 25 minutes at 59 degrees c. the optimum temperature for maximum growt ... | 1977 | 861834 |
| evaluation of human oral organisms and pathogenic streptococcus for production of iga protease. | iga protease is a proteolytic enzyme found in whole human saliva and in dental plaque that cleaves both secretory and myeloma iga of human origin to yield intact fabalpha and fcalpha fragments. to determine which bacteria are capable of producing this enzyme, we have examined a variety of strains normally found in the human oral cavity and a number of streptococci of known lancefield group serotype. streptococci of groups a, b, c, d, f, g, h, m, and n, streptococcus mutans, streptococcus sanguis ... | 1975 | 1168676 |
| oxygen tolerance of fresh clinical anaerobic bacteria. | the oxygen tolerance and sensitivity of 57 freshly isolated anaerobic bacteria from clinical specimens was studied. all the organisms tolerated 8 h or more of exposure to oxygen in room air. growth of the isolates in increasing oxygen concentrations demonstrated that the 57 isolates varied in oxygen sensitivity from strict to aerotolerant anaerobes. comparison of the oxygen tolerance and sensitivity showed that the most tolerant organisms (best survival after prolonged exposure) included anaerob ... | 1975 | 1176601 |
| fusobacterium in presumed actinomyces canaliculitis. | based on stained smears of material obtained from the canaliculus, three cases of canaliculitis were presumed to be caused by actinomyces. cultures of these cases showed fusobacterium to be the probable infectious agent producing the disease. | 1977 | 900231 |
| fecal microbial flora in seventh day adventist populations and control subjects. | a comparison of 13 vegetarian seventh day adventists with 14 nonvegetarian adventists revealed relatively few statistically significant differences in fecal flora. a separate study involved a comparison of vegetarian adventists (49 subjects), nonvegetarian adventists (45), and non-adventists on a conventional american diet (31) re: the incidence of the c. paraputrificum group in the fecal flora. the adventist groups had significantly fewer c. septicum and c. tertium isolates than the non-adventi ... | 1977 | 920638 |
| hepatic lesions and bacterial changes in mice during infection of fusobacterium necrophorum. | liver abscesses were induced in male albino mice within 1 week after intraperitoneal inoculation of viable fusobacterium necrophorum la19 culture. fusobacteremia was transitory and reached a peak 2 h after inoculation then sharply declined until its disappearance 24 h post inoculation. by contrast, the number of fusobacteria in the liver increased rapidly during the first 4 h post inoculation and continued to do so less rapidly until the last sampling time (48 h post inoculation). there were sma ... | 1977 | 922598 |
| simplified method for antimicrobial susceptibility testing of anaerobic bacteria. | a simple, abbreviated broth dilution test (tube test) utilizing a commercially available medium and inexpensive disposable materials, and which could be performed entirely in room air, was developed and used to test the susceptibility of 100 strains of anaerobic bacteria to clindamycin, chloramphenicol, ampicillin, and tetracycline. results are reported in categories of susceptibility: susceptible to concentrations surpassed in vivo with usual dosage, susceptible to concentrations surpassed in v ... | 1975 | 1190751 |
| "bad breath": presenting manifestation of anaerobic pulmonary infection. | three patients are described in whom a putrid breath odor was the only or fist manifestation of anaerobic infection of the lung. fever, productive cough, and pleuritic pain, common findings in anaerobic pulmonary infection, were not initally present. "bad breath" may be an early due to the presence of anaerobic pulmonary infection. | 1975 | 1203000 |
| modified lombard-dowell broth as a general growth medium. | a new liquid medium (modified lombard-dowell broth) was inoculated with stock culture strains of aerobic and anaerobic bacteria and compared with prereduced chopped-meat glucose inoculated with the same anaerobes. both broths were subcultured at 48 and 72 h to aerobic and anaerobic blood agar plates, and the numbers of colonies were compared after 48-h incubation of the agar plates. this was repeated with mixed cultures of both aerobes and anaerobes. for a period of 11 months all specimens recei ... | 1977 | 925150 |
| [necrobacillosis of the cattle in the irkutsk district]. | | 1977 | 929951 |
| anaerobic meningitis and bacteremia caused by fusobacterium species. | in the two cases of anaerobic meningitis and bacteremia caused by fusobacterium species described, upper respiratory tract infection preceded the onset of meningitis. isolation of the causative organism and appropriate antibiotic therapy resulted in cures in both patients. although extremely rare, these organisms should be considered as possible causative agents in meningitis when routine cultures are negative, and appropriate anaerobic culture techniques should be employed, especially when sinu ... | 1976 | 941888 |
| comparison of the in vitro bactericidal activity of human serum and leukocytes against bacteroides fragilis and fusobacterium mortiferum in aerobic and anaerobic environments. | in aerobic and anaerobic in vitro environments, fusobacterium mortiferum was killed by human leukocytes or serum alone or in combination; clinical isolates of bacteroides fragilis were killed only by leukocytes in the presence of serum. | 1976 | 965101 |
| anaerobic infections in surgery: clinical review. | anaerobic bacteria are being recognized with increasing frequency as important micro-organisms in surgical infections. clostridium, bacteriodes, fusobacterium, and peptostreptococcus are the clinically prominent pathological anaerobes. all are commensals and, consequently, most anaerobic infections are endogenous in origin. in the colon, anaerobes are 1,000 times more prevalent than aerobes. this has important implications regarding the management of gastrointestinal tract operations and the tre ... | 1976 | 1257897 |
| hyperbaric oxygen exposures for intrahepatic abscesses produced in mice by nonsporeforming anaerobic bacteria. | hyperbaric oxygen exposures were evaluated for treatment of progressive liver abscesses produced by intraperitoneal injection of combined cultures of fusobacterium necrophorum plus either bacteroides fragilis subsp. fragilis or fusobacterium nucleatum in a mouse model. infected control and hyperbaric oxygen-exposed mice were autopsied 5 or 6 weeks after inoculation of bacteria and were assigned numerical pathology scores according to the number and size of abscesses present. seventeen daily 3-h ... | 1976 | 1267430 |
| rosamicin: in vitro activity against anaerobes and comparison with erythromycin. | the in vitro activity of rosamicin was determined against 231 strains of anaerobic bacteria and compared with the activity of erythromycin against the same strains. rosamicin and erythromycin had similar activity against strains of peptostreptococcus and gram-positive nonsporeforming bacilli. rosamicin was somewhat more active against strains of peptococcus, clostridium, and gram-negative anaerobes. all strains of bacteroides fragilis tested were inhibited by 4 mug of rosamicin or less per ml, w ... | 1976 | 1267432 |
| in vitro susceptibility of common clinical anaerobic and aerobic isolates against josamycin. | the in vitro susceptibility of 145 anaerobic clinical isolates and 96 gram-positive aerobic clinical isolates to josamycin, a new macrolide antibiotic, was studied using the agar dilution technique. ninety-five of the aerobes were susceptible to 1.56 mug or less of josamycin per ml. the median minimal inhibitory concentration of these organisms was </=0.39 mug/ml. the in vitro activity of josamycin against the anaerobes was compared with that of erythromycin, clindamycin, penicillin, and chloram ... | 1976 | 984766 |
| susceptibility of respiratory tract anaerobes to orally administered penicillins and cephalosporins. | anaerobic bacteria recovered from airway-related infections were tested by agar dilution against selected penicillins and cephalosporins available for oral administration. against 136 isolates, penicillins g and v showed comparable activity, particularly when pharmacological differences were considered. although many isolates were exquisitely susceptible to the penicillins, only 55% of the bacteroides species and 72% of all isolates were inhibited at 0.5 mug of penicillin g per ml. results for p ... | 1976 | 984805 |
| [antibacterial and bactericidal activity of tinidazole against anaerobic bacteria comparing with metronidazole (author's transl)]. | antibacterial activity of tinidazole (1-2-(ethylsulfonyl)-2-methyl-5-nitroimidazole) against anaerobic bacteria including peptococcus, peptostreptococcus, eubacterium, propionibacterium, bacteroides and fusobacterium was studied by agar dilution method comparing with metronidazole. in addition to this work, bactericidal effect of tinidazole and metronidazole against p. prevotii, b. fragilis ss. fragilis and f. varium was examined by quantitative culture method after incubation in gam broth conta ... | 1976 | 1271586 |
| experimentally induced foot rot in feedlot cattle fed rations containing organic iodine (ethylenediamine dihydriodide) and urea. | foot rot was experimentally induced in feedlot cattle with a mixed inoculum of fusobacterium necrophorum (sphaerophorus necrophus) and bacteroides melaninogenicus. both bacteria were isolated from the lesions. isolates of f necrophorum from 2 of the lesions were serologically compared, using a passive hemagglutination test with the strain used to induce the lesions. these isolates were serologically similar but not identical, indicating antigenic change had occurred during animal passage. the ad ... | 1976 | 1275334 |
| absolute configuration of 3-hydroxy fatty acids present in lipopolysaccharides from various bacterial groups. | the absolute configuration of 3-hydroxy fatty acids has been studied, which are present in the lipopolysaccharides of the following bacteria: phodopseudomonas gelatinosa, rh. viridis, rhodospirillum tenue, chromobacterium violaceum, pseudomonas aeruginosa, bordetella pertussis, vibrio metchnikovii, vibrio cholerae, salmonella spp., escherichia coli, shigella flexneri, proteus mirabilis, yersinia enterocolitica and fusobacterium nucleatum. the 3-hydroxy acids were liberated by strong alkaline hyd ... | 1976 | 1278168 |
| development and characterization of porphyromonas gingivalis-specific rat t-cell clones. | porphyromonas gingivalis has been implicated as a major pathogen in periodontitis. to determine the role of t cells in the regulation of this disease, a method was developed for the generation and characterization of rat t-cell clones with antigen specificity to p. gingivalis whole cells. the clones studied so far demonstrated a t-helper (th) phenotype w3/13+, w3/25+, ox8- and ox22-. these t-cell clones proliferated in vitro in response to p. gingivalis, but not to other bacteria (prevotella int ... | 1992 | 1281976 |
| putative periodontal pathogens on titanium implants and teeth in experimental gingivitis and periodontitis in beagle dogs. | the microflora around titanium implants and teeth in 4 beagle dogs was analyzed in order to follow the longitudinal development from healthy conditions to experimental gingivitis and periodontitis. a 2-month plaque control program was performed to establish healthy conditions on titanium implants and control teeth (baseline, day 0). subgingival bacterial samples and radiographs were obtained. the plaque control was ceased and all measurements were repeated on day 21 (gingivitis). a new period of ... | 1992 | 1290791 |
| susceptibility of anaerobic bacteria to 23 antimicrobial agents. | the antimicrobial susceptibility of 492 anaerobic bacteria, the majority of which were recent clinical isolates, was determined by the agar dilution technique. penicillin g was active against most of the strains tested at 32 u or less/ml, but only 72% of bacteroides fragilis strains were susceptible at this level and 9% required 256 u or more/ml. ampicillin was effective against most of the strains except b. fragilis at 16 mug or less/ml. amoxicillin was active against only 31% of b. fragilis, 7 ... | 1976 | 984809 |
| resistance of anaerobic bacteria to antimicrobial agents in spain. | as a consequence of antibiotic consumption, the entire microbial ecosystem attached to man is evolving towards resistance. in spain, penicillin resistance (mic > 0.5 mg/l) is found in about 10% of peptostreptococcus, clostridium perfringens and eubacterium, and in 50% of veillonella. cefoxitin resistance ( > 2 mg/l) is present in 10 to 20% of peptostreptococcus and clostridium, and in 50% of eubacterium; 21% of bacteroides (fragilis group) strains are resistant to 16 mg/l. a very low rate of imi ... | 1992 | 1295754 |
| a simple method for rapid identification of sphaerophorus necrophorus isolates. | | 1976 | 1004237 |
| infection and labor. vii. microbial invasion of the amniotic cavity in spontaneous rupture of membranes at term. | the purpose of this study was to determine the frequency, microbiologic characteristics, and clinical significance of microbial invasion of the amniotic cavity in women with premature rupture of membranes at term. | 1992 | 1301006 |
| [significance of the fusospirillum complex (plaut-vincent angina)]. | the results are discussed of a retrospective study of 126 patients by whom an excess of the fusospirochaetal complex was found by direct microscopic examination of tonsillar material. these bacteria are not only found in unilateral ulcero-necrotic tonsillitis, but also in different other tonsillar and general diseases. vincent's angina appears almost exclusively in young persons, aged from 16 to 25 years; in the adolescence (16-20 years) it forms about 40% of all cases of acute tonsillitis. the ... | 1976 | 1015288 |
| the effect of 3 mouthrinses on plaque and gingivitis development. | the aim of this study was to evaluate the effect of 3 mouthrinses, listerine antiseptic (thymol), peridex (chlorhexidine), perimed (povidone iodine and hydrogen peroxide), and a placebo (water) on the development of dental plaque and gingivitis, when used as the only oral hygiene procedure for 14 days. 71 subjects were entered into a randomized, double-blind study. at the baseline examination, papillary bleeding score (pbs), and plaque index (pi) were registered, after which subjects received su ... | 1992 | 1310096 |
| [oral vibrions method of isolation and demonstration of their relation to sherophorus fusiformis]. | | 1976 | 1020709 |
| microbiology of healthy and diseased periodontal sites in poorly controlled insulin dependent diabetics. | a group of poorly-controlled insulin dependent diabetes mellitus (iddm) patients were examined in a cross-sectional design for total microbial levels, microbial incidence, and the percent levels of selected periodontal microorganisms. these organisms were selected on the basis of prior reports that associated them with either periodontal disease or health. one periodontally-healthy and one periodontally-diseased site were examined in each iddm patient. increased levels of the periodontal pathoge ... | 1992 | 1315389 |
| in vivo protection of fusobacterium necrophorum from penicillin by bacteroides fragilis. | a mixed infection of bacteroides fragilis and fusobacterium necrophorum was resistant to treatment with penicillin even though a pure f. necrophorum infection could be successfully treated with penicillin. since b. fragilis alone did not produce infection, these results indicate that b. fragilis can protect f. necrophorum from penicillin in vivo. the extent of protection afforded by a strain of b. fragilis was related to its level of resistance to penicillin. only a few cells of b. fragilis were ... | 1975 | 1041218 |
| in vitro activities of three of the newer quinolones against anaerobic bacteria. | the antimicrobial activities of three new quinolone compounds, sparfloxacin, temafloxacin, and win 57273, against anaerobic bacteria were determined in three separate studies. the wadsworth agar dilution technique using brucella-laked blood agar was used throughout. the activities of other antimicrobial agents, including ciprofloxacin, imipenem, chloramphenicol, metronidazole, cefotetan, cefoxitin, and amoxicillin-clavulanic acid, were also determined. the breakpoints of the new quinolones were ... | 1992 | 1317149 |
| the use of dna probes to examine the distribution of subgingival species in subjects with different levels of periodontal destruction. | the present investigation examined the distribution of 14 subgingival species at a total of 2299 sites in 90 subjects with different levels of periodontal destruction. subgingival plaque samples taken from the mesial aspect of each tooth were anaerobically dispersed, diluted and plated on non selective media. after anaerobic incubation, colonies were lifted to nylon filters and specific species detected using digoxygenin-labeled whole chromosomal dna probes. the mean total viable count for all s ... | 1992 | 1318331 |
| subgingival temperature (iii). relation to microbial counts. | the present investigation examined the relationship of selected bacterial species and subgingival temperature. 35 subjects were measured at 6 sites per tooth for clinical parameters and subgingival temperature. measurements were repeated for 21 subjects at 2 month intervals providing a total of 66 subjects visits. at each visit, subgingival plaque samples were taken from the mesial aspect of each tooth and anaerobically dispersed, diluted and plated on non-selective media. after anaerobic incuba ... | 1992 | 1321846 |
| synergistic effect of pyrophosphate and sodium dodecyl sulfate on periodontal pathogens. | our previous studies have shown that pyrophosphate (ppi), the anticalculus component of tartar-control dentifrices, inhibits the growth of organisms associated with coronal and root surface caries. the purposes of this investigation were to: 1) determine if periodontal pathogens are similarly susceptible to the growth-inhibitory properties of ppi; and 2) determine if combinations of pyrophosphate-sodium dodecyl sulfate (ppi-sds) inhibit growth synergistically. porphyromonas gingivalis, actinobac ... | 1992 | 1324304 |
| role of porphyromonas gingivalis 40-kda outer membrane protein in the aggregation of p. gingivalis vesicles and actinomyces viscosus. | porphyromonas gingivalis, an important pathogen in periodontitis, produces extracellular vesicles that aggregate with actinomyces viscosus cells. a 40-kda outer membrane protein (omp)-coding gene from p. gingivalis was cloned and the protein was found to be localized in these vesicles. the recombinant 40-kda omp did not show aggregation activity. however, affinity-purified antibody against the recombinant protein significantly inhibited aggregation of p. gingivalis vesicles with a. viscosus cell ... | 1992 | 1329700 |
| effect of clavulanic acid, sulbactam and tazobactam on three different beta-lactamases from bacteroides uniformis, clostridium butyricum and fusobacterium nucleatum. | the effect of three beta-lactamase inhibitors, clavulanic acid, sulbactam and tazobactam used in clinical practice were compared for their activity against purified beta-lactamases from bacteroides uniformis, clostridium butyricum and fusobacterium nucleatum. the enzymes from b. uniformis and c. butyricum were produced in fermenters under controlled growth conditions and the enzyme from f. nucleatum was produced in batch cultures. purification of the beta-lactamases was achieved by anion-exchang ... | 1992 | 1331018 |
| comparative in-vitro activity of azithromycin, macrolides (erythromycin, clarithromycin and spiramycin) and streptogramin rp 59500 against oral organisms. | the in-vitro activities of azithromycin, clarithromycin, spiramycin and rp 59500 were compared with erythromycin against a wide range of oral organisms which have been implicated in oral infections and/or endocarditis (clindamycin was included for oral streptococci). all compounds tested showed good activity against many of these organisms, although some variation was observed with different species. clarithromycin was the most active of the antibiotics tested against gram-positive anaerobes, in ... | 1992 | 1331019 |
| correlation of haemagglutination activity with trypsin-like protease activity of porphyromonas gingivalis. | porphyromonas gingivalis is a gram-negative anaerobic bacterium associated with various forms of periodontal disease. several characteristics of p. gingivalis are thought to contribute to its pathogenicity; these include haemagglutination and trypsin-like protease activity. previous studies suggest an association between haemagglutination and trypsin-like protease activity of p. gingivalis. to investigate this, two complementary quantitative experimental approaches were taken. five independent m ... | 1992 | 1332663 |
| sensitization of oral bacteria in biofilms to killing by light from a low-power laser. | biofilms of streptococcus sanguis, porphyromonas gingivalis, fusobacterium nucleatum and actinobacillus actinomycetemcomitans were prepared on the surfaces of agar plates and a number of compounds were screened for their ability to sensitize bacteria in these biofilms to killing by light from a 7.3 mw helium/neon (he/ne) laser. toluidine blue o and methylene blue enabled detectable killing of all four target organisms after exposure to he/ne light for 30 s. aluminium disulphonated phthalocyanine ... | 1992 | 1334649 |
| bacterial concentration fluorescence immunoassay (bcfia) for the detection of periodontopathogens in plaque. | a bacterial concentration fluorescence immunoassay (bcfia) was developed to rapidly detect periodontopathic bacteria in human plaque samples. the bcfia utilized fluorescent-tagged monoclonal antibodies (mabs) directed against the lipopolysaccharide of selected gram-negative bacteria. microorganisms identified in plaque using the bcfia included actinobacillus actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, and fusobacterium nucleatum. the immunoassay procedure involved com ... | 1992 | 1336047 |
| dna probe and enzyme analysis in periodontal diagnostics. | recent research in periodontology has indicated that a finite number of bacterial species are associated with periodontal disease. this has generated the hypothesis that periodontal disease is essentially an infection due to one or more of the putative periodontopathogens; i.e., the specific plaque hypothesis (sph). this microbial specificity paradigm has already changed the way researchers and some clinicians view periodontal disease. the clinician must heed several cautions signs, however, if ... | 1992 | 1336048 |
| antibacterial efficacy of root canal medicaments. | the antibacterial efficacy of four endodontic medicaments was studied in vitro. calcium hydroxide (calacept), camphorated parachlorophenol (cpcp), cresophene, and 2% iodine-potassium iodide (iki) were tested against four anaerobic microorganisms, streptococcus mutans, peptostreptococcus anaerobius, porphyromonus gingivalis and fusobacterium nucleatum, for 10 or 15 min. iki was effective only against f. nucleatum and p. gingivalis, and the others were effective against all four microorganisms. | 1992 | 1337555 |
| [changes of antimicrobial susceptibility of anaerobic bacteria from clinical specimens (author's transl)]. | the susceptibility to several commonly used antimicrobial agents was examined on approximately 900 isolates of various anaerobes from clinical specimens between october 1965 to may 1975, and the changes of susceptibility were investigated. antimicrobial agents tested were penicillin g (pc-g), ampicillin (ab-pc), cephaloridine (cer), erythromycin (em), josamycin (jm), lincomycin (lcm), clindamycin (cldm), chloramphenicol (cp) and tetracycline (tc). and thiamphenicol (tp) and doxycycline (dotc) we ... | 1975 | 1042183 |
| summer mastitis in heifers: studies on the seasonal occurrence of actinomyces pyogenes, peptostreptococcus indolicus and bacteroidaceae in clinically healthy cattle in denmark. | with the aim of investigating the seasonal occurrence of actinomyces pyogenes, peptostreptococcus indolicus, bacteroides melaninogenicus ss. levii and fusobacterium necrophorum, and thus the potential for development of summer mastitis, clinically healthy danish holstein-friesian heifers due to calve in the autumn were sampled from the teat tip, the conjunctiva and the oral cavity at 2-6 week intervals from 1979 to 1981. the overall isolation rates of f. necrophorum, p. indolicus and b. melanino ... | 1992 | 1348381 |
| immunoglobulins in milk from cows immunized with oral strains of actinomyces, prevotella, porphyromonas, and fusobacterium. | immunization of pregnant cows with bacteria leads to the presence of high concentrations of specific antibodies in colostrum and milk. a total of 14 cows was immunized with single strains of heat-killed oral bacteria or pools of strains of actinomyces, porphyromonas, prevotella, and fusobacterium. two cows were treated with adjuvant alone. the mean percentages of igg1, igg2, igm, and iga in all of the milks were 83.8, 3.8, 9.3, and 3.1, respectively. elisa and whole cell agglutination assays dem ... | 1992 | 1354674 |
| comparative bacteriological studies on summer mastitis in grazing cattle and pyogenes mastitis in stabled cattle in denmark. | a total of 143 secretions from clinical cases of summer mastitis (sm) in grazing cattle and from 89 cases of pyogenes mastitis (pm) in stabled cattle were examined bacteriologically. the typical bacteriological finding was a mixed flora in which the predominant organisms were actinomyces pyogenes (sm-70%, pm-85%), peptostreptococcus indolicus (54%, 54%), a microaerophilic coccus (stuart-schwan coccus) (26%, 25%), fusobacterium necrophorum biovar b (22%, 12%), bacteroides melaninogenicus (20%, 9% ... | 1992 | 1355316 |
| cd45ra and cd45ro positive cd4 cells in human peripheral blood and periodontal disease tissue before and after stimulation with periodontopathic bacteria. | flow cytometric analysis was used to examine naive and primed or memory cd4 cells extracted from periodontal lesions compared with cells from peripheral blood of healthy subjects before and after stimulation with the periodontopathic bacteria, porphyromonas gingivalis and fusobacterium nucleatum. in peripheral blood, approximately 60% and 40% of cd4 cells were cd45ro+ and cd45ra+ respectively at day 0. phytohaemagglutinin (pha) induced cd45ro expression on almost 100% of cd4 cells. however, p. g ... | 1992 | 1356262 |
| different responses in b cells induced by porphyromonas gingivalis and fusobacterium nucleatum. | a phenotypic study had shown that gingival b cells respond differently to two periodontopathic bacteria, porphyromonas gingivalis and fusobacterium nucleatum. further investigation now shows a reduction in the percentage of ki-67 + t cells in cultures of gingival and peripheral blood mononuclear cells stimulated with p. gingivalis for 3 and 6 days, respectively, but no suppression of ki-67 expression in b cells in response to either p. gingivalis or f. nucleatum. depletion studies of cultures of ... | 1992 | 1359860 |
| the management of acute, serous and chronic otitis media: the role of anaerobic bacteria. | otitis media (om) is a common childhood disease and one which can cause significant morbidity. a knowledge of the pathogens responsible for om enables the most appropriate treatment regimen to be selected and thus minimizes further complications which may require hospital admission and surgery. the microbiology of acute, serous and chronic om is reviewed, with particular regard to the role of anaerobic bacteria. anaerobes, mainly gram-positive cocci, have been recovered from 25% of the ear aspir ... | 1992 | 1362753 |
| sensitization of oral bacteria to killing by low-power laser radiation. | twenty-seven compounds were screened for their ability to sensitize streptococcus sanguis to killing by light from a 7.3-mw helium/neon (hene) laser. bacteria were mixed with various concentrations of the test compounds, spread over the surfaces of agar plates, and then exposed to light from the hene laser for various time periods. the plates were then incubated and examined for zones of inhibition. those compounds found to be effective photosensitizers were then tested against porphyromonas gin ... | 1992 | 1369193 |
| microbiologic and pathologic aspects of pulpal and periapical disease. | the greatest cause of endodontic and periapical pathosis is microbial infection of the pulp. most odontogenic infections are of a polymicrobial nature. with advances in anaerobic isolation and culturing techniques, much has been learned about the presence of pathogenic organisms such as porphyromonas and prevotella species (formerly classified as black-pigmented bacteroides species) in infected root canals. this review provides a summary of recent developments in endodontic microbiology, virulen ... | 1992 | 1381632 |
| the establishment of human t cell lines reactive with specific periodontal bacteria. | human t cell lines (tcls) were obtained by stimulation of peripheral blood mononuclear cells (pbmcs) with the 2 periodontopathic bacteria, porphyromonas gingivalis fdc-381 and fusobacterium nucleatum fdc-263. after the first round of stimulation and rest, the cells responded specifically to the bacteria originally used to establish each line. throughout the culture period, the responsiveness of each of the tcls to their specific bacteria increased. phenotypic analysis of the tcls revealed hetero ... | 1992 | 1383912 |
| isolation and identification of intestinal bacteria from japanese tree frog (hlya japonica) with the special reference to anaerobic bacteria. | the bacteria in the large intestines of eight japanese tree frogs (hlya japonica) were enumerated by using an anaerobic culture system. the microorganisms at approximately 3.1 x 10(9) bacteria per g (wet weight) of intestinal contents were present in the intestine of all the frogs tested. no difference of the total bacteria in the frog intestine was observed between two different incubation-temperatures (room temperature and 37 degrees c). eleven genera and 16 species were isolated from the frog ... | 1992 | 1391180 |
| complications of peritonsillar abscess due to fusobacterium necrophorum. | | 1976 | 1063358 |
| identification of proteases from periodontopathogenic bacteria as activators of latent human neutrophil and fibroblast-type interstitial collagenases. | activation of latent human fibroblast-type and neutrophil interstitial procollagenases as well as degradation of native type i collagen by supra- and subgingival dental plaque extracts, an 80-kda trypsinlike protease from porphyromas gingivalis (atcc 33277), a 95-kda chymotrypsinlike protease from treponema denticola (atcc 29522), and selected bacterial species commonly isolated in periodontitis was studied. the bacteria included were prevotella intermedia (atcc 25261), prevotella buccae (es 57) ... | 1992 | 1398963 |
| case records of the massachusetts general hospital. weekly clinicopathological exercise. case 17-1975. | | 1975 | 1090833 |
| indirect fluorescent antibody procedure for the rapid detection and identification of bacteroides and fusobacterium in clinical specimens. | an indirect fluorescent antibody (ifa) technique was evaluated as a procedure for rapid detection and identification of members of the bacteroidaceae. antisera were prepared against 31 members of this family, including species of bacteroides and fusobacterium commonly isolated from human infections. the antisera had demonstrated species and/or subspecies specificity. thirty clinical specimens were studied. of 13 specimens yielding bacteroidaceae, for which antisera were available, 23 were presum ... | 1975 | 1102560 |
| experimentally induced infection by oral anaerobic microorganisms in a mouse model. | a mouse model was developed to study the abscessogenic potential of pure and mixed cultures of oral anaerobes associated with infections of endodontic origin. maximum subcutaneous lesions were seen on their backs between 3 and 14 d after inoculation. strains of fusobacterium nucleatum, peptostreptococcus anaerobius, and veillonella parvula were pathogenic in pure culture. a mixed culture of f. nucleatum with either porphyromonas gingivalis or prevotella intermedia was significantly more pathogen ... | 1992 | 1408362 |
| biological characterization of fusobacterium necrophorum. cell fractions in preparation for toxin and immunization studies. | fusobacterium necrophorum isolated from bovine liver abscesses was grown in bulk at 37 c for 24 h under a strict anaerobic atmosphere. harvested washed cells were disrupted ultrasonically and fractionated by differential centrifugation into the intracellular (cytoplasm) and cell wall fractions. both intact cells and cell fractions induced generalized cytopathic effect on primary pig kidney cultures and caused a variety of signs of illness and/or death of intraperitoneally injected mice. the inta ... | 1975 | 1120608 |
| fusobacterium septicemia with otitis media and mastoiditis. | | 1975 | 1124245 |
| sphaerophorus necrophorus: laboratory model for the evaluation of chemotherapeutic agents in mice. | severe necro-purulent lesions were induced in mice following parenteral inoculation of sphaerophorus necrophorus. gross and histological changes observed in the lung, liver, and foot pad of infected mice were similar to those occurring naturally in cattle. the lesions could be prevented, cured or significantly reduced by the administration of chemotherapeutic agents such as sulfonamides, potentiated sulfonamide and antibiotics. the application of this novel laboratory model infection in the prim ... | 1975 | 1126167 |
| therapeutic evaluation of minocycline and tetracycline for mixed anaerobic infection in mice. | minocycline has demonstrated greater in vitro activity against anaerobic bacteria than its parent compound, tetracycline. in vivo therapeutic efficacy of the two drugs was tested against a mixed anaerobic infection in a mouse model. fusobacterium necrophorum plus f. nucleatum injected intraperitoneally produced progressive intrahepatic and occasional extrahepatic abscesses, which were measured at autopsy. three treatment regimens were tested, single daily doses of antibiotic being administered b ... | 1977 | 856014 |
| complement activation by lipopolysaccharides purified from gram-negative bacteria isolated from infected root canals. | the purpose of the present study was to investigate the complement activation by lipopolysaccharides purified from porphyromonas (bacteroides) endodontalis, veillonella parvula, and fusobacterium nucleatum isolated from infected root canals. the rate of consumption of the c3t component of the complement increased remarkably when lipopolysaccharides of more than 10 micrograms were added. | 1992 | 1437068 |
| fusobacterium necrophorum and bacteroides melaninogenicus as etiologic agents of foot rot in cattle. | fusobacterium necrophorum (sphaerophorus necrophorus) and bacteroides melaninogenicus were the predominant bacteria isolated from biopsy specimens of lesions in cattle affected with foot rot. mixed inoculums of the 2 bacteria, applied to the scarified interdigital skin or inoculated intradermally into the interdigital skin of test cattle, induced typical lesions of foot rot. both bacteria were reisolated in large numbers from the induced lesions. | 1975 | 1155832 |
| delayed post-traumatic subdural empyema. | a case of subdural empyema is reported, treated through a frontal bone flap, with exenteration of the infected frontal sinus at operation, and subdural instillation of antibiotics for 48 hours postoperatively. diagnostic findings are reviewed, and the likelihood of anaerobic infection this case and similar cases discussed. | 1975 | 1177340 |
| comparison of cefoxitin and cephalothin therapy of a mixed bacteroides fragilis and fusobacterius necrophorum infection in mice. | cefoxitin, a beta-lactamase-resistant cephalosporin, was found to be more effective than cephalothin against an experimental mixed infection containing bacteroides fragilis and fusobacterium necrophorum. | 1975 | 1180547 |
| susceptibility of the liver and biliary tract to anaerobic infection in extrahepatic biliary tract obstruction. bacteriological investigations - an experimental study in rabbits. | the influence of common duct occlusion on susceptibility to infection with anaerobic gram-negative rods was investigated in rabbits. intravenous inoculation was performed with three b. fragilis strains isolated from human infections and with a stock culture of fusobacterium mortiferum. liver tissue, gallbladder, bile, and blood were investigated. anaerobic culture procedures were based on the use of a 'glove-box' with an oxygen-free atmosphere and pre-reduced, anaerobically sterilized media. ana ... | 1975 | 1188311 |
| phenolic constituents in erythrina x bidwilli and their activity against oral microbial organisms. | five flavonoid compounds, including two new isoflavanones, were isolated from the root bark of erythrina x bidwilli. their structures were determined to be 2,10-di(gamma,gamma-dimethylallyl)-3,9-dihydroxypterocarpan (erythrabyssin ii), 6,8-di(gamma,gamma-dimethylallyl)-7,2',4'-trihydroxyisoflavanone (bidwillon a), 8-gamma,gamma-dimethylallyl-2',4'-dihydroxy-[6",6"-di-methylpyrano - (2",3":7,6)]isoflavanone (bidwillon b), 8-gamma,gamma-dimethylallyl-7,4'-dihydroxyisoflavone (8-gamma,gamma-dimethy ... | 1992 | 1464104 |
| experimental studies of survival of anaerobic bacteria at 4 degrees c and 22 degrees c in two different transport systems. | the survival of anaerobic bacteria on swabs in two different transport systems at 4 degrees c and 22 degrees c was evaluated. the transport systems were a charcoal-impregnated cotton swab in modified stuart transport medium (mst), and a viscose swab in modified siff transport medium (btm) (bionor). the following eight clinical strains of anaerobic bacteria were tested for quantitative recovery at 24 h, 48 h, 72 h, and 96 h; fusobacterium necrophorum, bacteroides melaninogenicus, bacteroides inte ... | 1992 | 1472363 |