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cyclic kinetics and mathematical expression of the primary immune response to soluble antigen. vii. the conveyer hypothesis and its mathematical expression.the conveyer hypothesis is based on the fact that because of clone predetermination, antibody production takes place in an organism without the presence of antigen as a result of natural cell differentiation. soluble antigen is an analogue of a specific mitogen which gives rise to reproduction mainly of cells carrying on their surface the immunoglobulin receptors to the given antigen. the mathematical model of the conveyer hypothesis takes into account the initial conditions, among them the back ...1977557428
diseases of the commercial rabbit.throughout its short history, the commercial rabbit industry has suffered from a poor home market due to the long national memory of the 1950s myxomatosis outbreak, the strong competition from the broiler chicken industry and of low-priced imported rabbit. in the past few years, a new market for british rabbit has opened up in europe with a potential demand far in excess of the present production. the veterinary profession can assist in this expansion.1977562555
the response of turkeys to varying doses of live oral pasteurella multocida vaccine.groups of 30 turkeys were vaccinated by the drinking water route against fowl cholera with varying doses of the low virulence, cu strain, of pasteurella mulocida. one group (heavy dose) received 1.2 x 107, another (medium dose) 1.5 x 105, and a third (light dose) 1.0 x 103 bacteria per ml. of drinking water. two (6.7%) vaccine induced cholera deaths occurred in the heavy dose group. no deaths resulted in the other groups. maximum serum antibody titers per group were; light dose 1:32, medium dose ...1977605007
an evaluation of the effect of various concentrations of the clemson university pasteurella multocida drinking water vaccine on the immune response against fowl cholera disease in turkey. 1977605013
case report: treatment of catbite injuries of the hand.catbite or scratch injuries frequently contain mixed organisms, and penicillin or erythromycin alone may not give adequate coverage, as shown in the cases described. incision and drainage should not be neglected or deferred when a deep infectious process is present or bones, joints, or tendon sheaths are involved. finally, a catbite injury is a deep penetration injury with potentially virulent organisms that require close followup and awareness of potential problems.1979572432
pasteurella multocida bacteremia associated with peritonitis and cirrhosis.pasteurella multocida has been the etiologic agent in at least three cases of "spontaneous" bacterial peritonitis (sbp). we report another patient with p. multocida bacteremia and sbp and suggest that there may be more than a chance association between cirrhotic liver disease and this unusual organism which rarely causes sepsis in man.1977607799
attenuated live fowl cholera vaccine. i. development of vaccine strain m3g of pasteurella multocida.a live cholera vaccine was developed from a virulent avian septicemia strain of pasteurella multocida serotype 1. the virulent parental strain was mutagenized with n-methyl-n'-nitro-n-nitroso guanidine. mutants were selected that had either smaller colonies at 37 c or temperature sensitivity for growth at 41 c. four small-colony mutants and 2 temperature-sensitive mutants were studied. all the mutants were avirulent for turkeys. sixteen days after turkeys were vaccinated with each mutant, both t ...1979546409
attenuated live fowl cholera vaccine. ii. some biological properties of strain m-3-g. 1979546410
attenutated live fowl cholera vaccine. iii. laboratory and field vaccination trials in turkeys and chickens.administered via the drinking water, m-3-g, an attenuated strain of pasteurella multocida of serotype 1, was found to immunize turkeys and chickens against fowl cholera. immunity was tested by challenging birds intramuscularly, by palatine cleft swab, or orally after 3 vaccinations. no reactions to vaccination were noted in 390 turkeys in 12 laboratory trials, nor in 20,245 vaccinated in field trials. chickens showed no vaccination reactions, and immunity was elicited by challenge in a laborator ...1979546411
influence of encapsulation on phagocytosis of pasteurella multocida by bovine neutrophils.the effect of encapsulation on phagocytosis of pasteurella multocida by bovine neutrophils was examined by using two encapsulated strains, na77 (capsular type a) and c42 (capsular type b), and comparing them with an unencapsulated counterpart strain, 1173. the uptake of [(3)h]thymidine-labeled bacteria by neutrophils was quantitatively measured after incubation of the bacteria in normal bovine serum, heat-inactivated serum, and hyperimmune sera (anti-na77 and anti-c42). results showed that all t ...1979574125
a field outbreak of suspected stachybotryotoxicosis in sheep.an outbreak of mortality in a flock of mutton merino sheep in which 109 out of 568 sheep died in the south-western cape province, is described. it was characterized by haemorrhagic septicaemia, anaemia, leucocytopaenia and haemorrhagic tendencies. mortalities followed unseasonal and heavy summer rain, extended over a period of 6 months and were associated with the uninterrupted consumption of sheep cubes processed on the farm severly fungus-infested wheat, barley and rye straw for a period of at ...1979575906
evaluation of aureomycin for prevention of arthritic, pulmonary and cranial forms of fowl cholera in turkeys.aureomycin fed at concentrations of 55, 110, and 220 mg./kg. of feed significantly (p less than 0.05) increased livability as compared to that of the nonmedicated exposed and increased average body wieght gained per turkey as compared to that of both the nonmedicated exposed and nonmedicated nonexposed turkeys. the increase in survival was proportional to the increase in concentration of aureomycin in the feed. turkeys were exposed, in the drinking water, to three isolates of pasteurella multoci ...1977605074
rapid plate agglutination procedure for serotyping pasteurella haemolytica.a specific, rapid plate agglutination procedure for serotyping pasteurella haemolytica was performed. the procedure did not require special antigen preparation and yielded essentially the same results as the indirect hemagglutination procedure.1978632345
aerobic bacterial flora of oral and nasal fluids of canines with reference to bacteria associated with bites.oral and nasal fluids of 50 dogs were examined to determine the prevalence of aerobic bacteria frequently associated with animal bite wounds. the most frequently isolated microorganisms included: iij, ef-4, pasteurella multocida, staphylococcus aureus, staphylococcus epidermidis, group d streptococci, corynebacterium sp., enterobacteria, neisseria sp., moraxella sp., and bacillus sp. other species and genera were infrequently recovered and may represent transient flora. the high incidence of iij ...1978632349
human pulmonary pasteurellosis.pasteurella multocida causes hemorrhagic septicemia in many domestic and wild animals. the most common human infection with p multocida is a local cellulitis following animal-inflicted wounds, preponderantly cat bites and scractches. the typical clinical manifestations and complications have been well described previously. we present three cases of pulmonary pasteurellosis that were recently evaluated by the infectious diseases service at barnes hospital. in three additional cases, the technolog ...1979582610
comparison of cefazedone with cefazolin and cephalothin in treatment of experimental infections in mice.the chemotherapeutic efficacy of (6r,7r)-7-(2-[3,5-dichloro-4-oxo-1(4h)-pyridyl]-acetamido)-3-([(5-methyl-1,3,4-thiadiazol-2-yl)-thio)-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid (cefazedone, refosporen) was assayed in comparison to cefazolin and cephalothin in experimental bacterial murine infections with 6 gram-positive and 8 gram-negative strains of the genera staphylococcus, streptococcus, pneumococcus, escherichia, klebsiella, proteus, pasteurella and salmonella. in 5 out of ...1979582716
[dynamics of immunogenesis in the vaccination of animals against pasteurellosis and anaerobic infections]. 1978566981
demonstration of cross-protection between pasteurella multocida type a and pasteurella haemolytica, serotype 1.mice immunized with the potassium thiocyanate extract of pasteurella haemolytica, serotype 1, were found to resist a challenge infection of p. multocida type a, thus demonstrating cross-protection. this finding was further supported by the finding that an antiserum directed against the potassium thiocyanate extract of p. haemolytica was bactericidal to p. multocida and vice versa.1977591058
[experimental study of a mouse model with attenuated mutants of a pasteurella multocida strain pathogenic to calf. 3: isolation and biological characterization of temperature-sensitive mutants and testing of their immunogenicity in comparison to streptomycin-dependent germs]. 1977603350
response of young chickens and turkeys to virulent and avirulent pasteurella multocida administered by various routes.groups of 20 young chickens and turkeys obtained from commercial flocks and placed in pens with pine shavings over concrete floors or from the hatchery and grown on wire, were exposed to avirulent pasteurella multocida serotype 3,4 cross or virulent p. multocida serotype 3 by drinking water, ocular, subcutaneous, intracutaneous, or palatine cleft routes. a secondary exposure to virulent p. multocida serotype 1 by the palatine cleft route was given 14 days later, except that birds exposed by pala ...1978646754
a new serotype of pasteurella multocida associated with fowl cholera.gel-diffusion precipitin tests demonstrated an additional pasteurella multocida serotype, designated serotype 16. isolate p-2723, antigenically distinct from the other (previously reported) 15 serotypes, was from a turkey affected with fowl cholera. this serotype is not widely distributed. isolate p-2723 was of mild virulence in turkeys, resulting in local infections in the hock joint and sternal bursa of only 1 of 9 turkeys exposed.1978646758
[serological typing of isolates of pasteurella multocida from poultry and other animals in the netherlands (author's transl)].pasteurella multocida isolates, isolated from poultry, birds and mammals in the netherlands, were typed serologically. the standard sera were directed against heddleston reference strains. of the 202 isolates, 37.6 per cent were of type 1, 24.2 per cent of type 3, 2 per cent of type 5, 5.9 per cent of type 10 and 3.5 per cent of type 12. cross reactions with two serotypes were shown by 18.8 per cent of the other isolates and with three serotypes by 3.5 per cent. the serotype of p. multocida isol ...1978567387
the pasteurella carriers in farm and laboratory animals. 1979548204
interaction between a hog cholera vaccine strain and pasteurella multocida in the production of porcine pneumonia. 1978659677
synthesis and antibacterial activity of isomeric 6- and 7-acetyl-3-methyl-2- quinoxalinecarbozamide 1,4-dioxides.the synthesis, separation, and structure determination of 6- and 7-acetyl--3-methyl-2-quinoxalinecarboxamide 1,4-dioxides are reported together with a comparison of their antibacterial activity. the structural assignment of these 6- and7-acetyl isomers was based on nmr analysis of related mono-n-oxide derivatives, which were obtained by treatment of the quinoxaline 1,4-dioxides with acetic anhydride--acetic acid or trimethyl phosphite. the compounds were screened for in vitro and in vivo activit ...1978660596
immunologic and physiologic responses of calves inoculated with potassium thiocyanate extract of pasteurella multocida type a.inoculation of calves with potassium thiocyanate (kscn) extract of pasteurella multocida type a in saline-tris buffer or in freund's incomplete adjuvant or modified freund's incomplete adjuvant resulted in the elicitation of agglutinating, hemagglutinating, bactericidal and homocytotropic antibodies. the antibody response was significantly (p = 0.05) higher in calves inoculated with the kscn extract in either adjuvant than in those inoculated with the extract in saline-tris buffer. hemagglutinat ...1978567948
[experimental pasteurella multocida infection of swine. a contribution to the etiology of enzootic porcine pneumonia].pasteurella can be isolated from about 50 per cent of pneumonically changed pig lungs. isolation, however, is possible also from intact lungs of conventional or secondary spf animals. the authors of this paper used the positive hyaluronidase test and identified exclusively pasteurella multocida, with predominance of capsular type a. most of the pasteurella strains tested in this context caused pneumonia in spf animals, particularly, following intratracheal application. no correlations were found ...1977603359
evaluation of rofenaid and a commercial bacterin for prevention of cranial form of fowl cholera in turkeys.rofenaid, a potentiated sulfadimethoxine at drug concentrations of 0.04, 0.02, and 0.01% in feed, a combination of vaccination with a commercial bacterin and 0.01% potentiated sulfadimethoxine (rofenaid), and vaccination separately, significantly (p less than 0.05) increased livability of turkeys experimentally induced with the cranial form of fowl cholera as compared to that of the nonmedicated nonvaccinated exposed turkeys. turkeys were exposed by the administration of pasteurella multocida (i ...1977605073
[problems in the use of radioactively labelled bacteria in experiments. 2. quantitative method for the evaluation of pathogens in the calf lung by means of labelled bacteria after aerosol or intratracheal administration].by means of two aerosol apparatures radioactive labelled pasteurella-multocida-germs were given to calves via a respiratory mask. labelling of pasteurellae was done internal by using special nutritive media with fe-59 or p-32. in a period of 10-25 minutes 5 x 10(9)-10(10) labelled bacteria were given to the animals for inhalation. another animal group was injected intratrachealy with the same quantity of labelled germs. immediately after termination of germ application the animals were killed an ...1977603372
an outbreak of erysipelas in coturnix quails.a severe outbreak of erysipelas causing high mortality was observed in coturnix breeder quails. possible source(s) of erysipelothrix infection in the flock and subsequent infections due to pasteurella multocida, salmonella typhimurium, and staphylococcus aureus are discussed.1977606226
growth curves and stabilization of fresh vaccine cultures of the clemson university strain of pastuerella multocida.growth curves at 37 c for the clemson university strain of pasteurella multocida were about the same in either brain-heart-infusion broth or in a recently developed broth called "special broth tv". counts in both broths were usually greater than 1 x 10(9) viable bacteria per ml. with the addition of 5 g of dried skim milk to each 100 ml of broth culture in the stationary phase of the growth curve, only a slight decrease in viable counts occurred over the next 7 to 14 days when held at 4 c. such ...1978674040
pasteurella anatipestifer infection in turkeys.in a case of excessive mortality in seven-week-old turkeys, the primary lesion at necropsy was severe fibrinous pericarditis and epicarditis. after 48 hours of incubation at 37 c, pasteurella anatipestifer was isolated. the infection responded to antibiotic therapy with a combination of neomycin and oxytetracycline in the drinking water. the lesions suggested chlamydial infection, but cultural procedures for chlamydia were negative.1977606228
a microtiter agglutination test for anti-pasteurella multocida antibodies in turkeys.a microtiter agglutination test (mta) was developed for assaying anti-pasteurella multocida antibodies in turkeys vaccinated with live avirulent clemson university (cu) strain. safranine-o was incorporated with the decapsulated p. multocida antigen and greaterly enhanced the visibility of the sedimented free antigen, which formed a compact red button on the bottom of the well. the advantages of the mta test over the tube agglutination test were that: 1) less antigen and serum were required; 2) d ...1979546401
treatment of pasteurella multocida infection after dogbite by ampicillin wound irrigation. a case report. 1977610289
observation on the bacterial population of the os cervix of the ewe before and after embryo death.bacterial samples were isolated from the os cervix of mature merino ewes during a normal oestrous cycle and after colchicine treatment which killed the 25-day old embryos. the population of bacteria was small during the oestrous cycle and consisted of achromobacter spp. alcaligenes spp, corynebacterium spp, bacillus spp and escherichia coli. there was a significant increase in the numbers of bacteria isolated and a change in the proportions of the bacteria isolated from ewes after embryo death. ...1977612334
serological types of pasteurella haemolytica in kenya.the 12 known serotypes of p. haemolytica and two biotypes a and t were found to occur in kenya. biotype t was more common in disease conditions than biotype a, which was more common in the nasal passages of healthy animals. only biotypes a strains were recovered from cattle and the majority were serotypes 1 and 2, but serotypes 4 and 11 were also isolated. all serotypes were found to occur in sheep and goats, but serotypes 3, 4, 6, 8 and 10 were more commonly associated with pneumonia. it was ob ...1978618717
pasteurella ureae meningoencephalitis. 1978619086
endobronchial inoculation of sheep with pneumonic lung-tissue suspensions and with the bacteria and mycoplasmas isolated from them. 1978621307
isopycnic characterization of lipopolysaccharides from pasteurella multocida. 1978629385
the 1978 epornitic of avian cholera on the chesapeake bay.in an outbreak of avian cholera (pasteurella multocida infection) in wildfowl on and around chesapeake bay during march and april of 1978, 31,295 carcasses were retrieved from maryland and virginia. although other birds were involved, mortality was heavy among diving ducks (90% of the total), especially oldsquaw ducks (80% of the total). this is the second outbreak involving primarily diving ducks to be reported from this area of the atlantic flyway. it mimics in many respects the epornitic that ...1979546415
the january 1977 avian cholera epornitic in northwest california.a total of 844 birds were observed dead at three sites in humboldt county and an estimated 6750 birds died at three sites in del norte county, california. coots were the primary species affected. the isolation of pasteurella multocida from a snowy egret (egretta thula) is the first reported case of avian cholera in this bird. there was evidence for a distinct sequence in the bird species dying at one site; american coots (fulica americana) appeared to be the first species to die.1978691123
pasteurella multocida brain abscess following perforating cranial dog bite. 1978633019
treatment of common dog bites: infection risk factors.in a retrospective study of 106 patients with complete follow-up of dog bites treated in the emergency department the following factors greatly increased the risk of infection: age greater than 50 years, delay in seeking treatment, location on an upper extremity, and puncture wounds. debridement and irrigation decreased the incidence of infection, and sutured wounds were not more likely to become infected than those left open. prophylactic antibiotics provided no benefit in this series. in the l ...1978633680
characterization of a pasteurella multocida bacteriophage.the pasteurella multocida bacteriophage b939a produces turbid plaques, which suggests infection with a temperate phage. attempts to induce production of lytic phage by uv irradiation were unsuccessful, however, bateriophage b932a is highly stable at 4 c and relatively stable at room temperature. it tolerates moist heat at 60 c, but is inactivated at 70 c in 10 minutes. morphologically, it is a tailed phage with a hexagonal head.1978697170
pasteurellosis in sheep.pasteurellosis is an important cause of economic loss to the sheep industry. there are two distinct syndromes. the pneumonic form of the disease caused by p haemolytica biotype a occurs as pneumonia in flocks and sporadically in individual sheep. the septicaemic form, caused by p haemolytica biotype t is associated with hyper-acute disease and occurs most commonly in the autumn coinciding with the folding of hoggs on rape, turnips and improved pastures. the factors which predispose sheep to the ...1978636244
[electron microscopic studies of pasteurella multocida bacteriophages].studied was the morphology of four pasteurella multocida phages, nos. 115, 32, 967, and 1075, with the use of an electron microscope. the bacterial phages had hexagonal heads of a 55 x 55 nm diameter, and were of an isometric polygonal form themselves. the tail of the phages was 120 nm long and was non-contractile. by these characters the p. multocida phages are to be referred to the morphologic group of phages of noncontractile tails--group b after bradley and group iv after tihonenko.1977605495
fowl cholera: immunization of chickens with potassium thiocyanate (kscn) extract of pasteurella multocida serotype 3.potassium thiocyanate (kscn) extract of pasteurella multocida, serotype 3, was found to be immunogenic against a challenge infection of homologous as well as one heterologous strain tested (serotype 1). ouchterlony's gel-diffusion analysis revealed the presence of two components in the kscn-extracts of both serotypes 3 and 1, which were antigenically identical.1977606217
modulation of cross-protection factor(s) of avian pasteurella multocida.cross-protection factor(s) (cpf) of pasteurella multocida were maintained in vitro through at least 9 serial passages. different growth media and temperatures enhanced or repressed the ability of p. multocida to produce cpf. certain amino acids were innoculous to expression of cpf. b-vitamins enhanced cpf, whereas certain inorganic salts repressed cpf. the plasma of normal tuekeys contained a compound or compounds that were responsible for expression and maintenance of cpf.1979546418
[etiology of infectious atrophic rhinitis in swine]. 1978636291
a case of septicemia and meningitis in an infant due to pasteurella multocida. 1978641644
the 1975-76 avian cholera outbreaks in humboldt county, california.the 1975-76 avian cholera outbreaks were observed from 25 november 1975 to 17 february 1976 at three sites in humboldt county, california. this is the first known occurrence of avian cholera on one of the sites (city of arcata oxidation ponds).1978650790
avian cholera in eider ducks in maine.outbreaks of avian cholera (pasteurella multocida) occur frequently in common eiders (somateria mollissima dresseri) in maine during early summer. studies over a seven year period show that over 90% of the loss occurred in incubating females and might be associated with their weakened condition because females do not feed during the incubation period. high nesting densities also may contribute to the losses. the exact source of p. multocida is unknown although carrier birds were found.1978650794
pasteurella multocida pleural empyema. 1978722450
[effect of aspirin and indomethacin on changes caused by pateurella multocida toxins in calves].acetylsalicyclic acid acid (50 mg/kg die) and indomethacin (1.5 mg/kg die) were administered to calves three days prior to intravenous application of endotoxin. such treatment resulted in delayed occurence of clinical symptoms and higher survival rates, as compared to untreated controls. parameters relating to coagulation physiology, changed by endotoxin, were not controllable with statistical security by administration of acetylsalicyclic acid indomethacin.1978666518
induction of pneumonia in mice with pasteurella haemolytica. 1978670447
pharmacokinetics of penicillin g in the turkey.parmacokinetics of penicillin g was determined for the turkey. the study was prompted by the isolation of a sulfonamide-resistant strain of pasteurella multocida from tissues of turkeys involved in an outbreak of fowl cholera and the subsequent discovery that little pharmacologic information was available concerning other antimicrobial agents in that species. penicillin g was chosen for study because p multocida is susceptible to this antibiotic. the elimination of the antibiotic followed first- ...1978677541
a case report of total knee arthroplasty infected by pasteurella multocida.a 72-year-old woman with a total knee prosthesis was infected with pasteurella multocida organisms from a cat bite. the joint was successfully salvaged by surgical debridement, closed tube irrigation utilizing .25% acetic acid and appropriate antibiotics.1978679534
treatment of pasteurella pneumotropica abscesses in nude mice (nu/nu). 1978732265
hazards of disease transfer from marine mammals to land mammals: review and recent findings.in a 5-year study (1972-1977) of microbial agents isolated from both clinically normal and diseased marine mammals, it was shown that certain disease agents are widespread in a diversity of ocean populations and that some are also transmissible to a number of terrestrial mammal species. leptospira interrogans serovar pomona has been isolated repeatedly from 2 species of pinnipeds (zalophus californianus califonianus and callorhinus ursinus). some of the more important bacterial pathogens for lan ...1978738931
effect of bursectomy and thymectomy on pasteurella multocida infection in chickens.the effects of various treatments on the immune response of chickens to vaccine prepared from pasteurella multocida strain p1059 were investigated. the treatments, given on or before the day of hatching, consisted of surgical bursectomy (sb), hormonal bursectomy (hb), surgical thymectomy (st) and x-irradiation (x). in chickens subjected to sb, sbx or hb before vaccination, the production of agglutinin and immunoglobulin was impaired, but the production of resistance against challenge was not. in ...1978682178
[pasteurella multocida infections in man unrelated to animal bites]. 1978740987
chronic necrotizing mastitis in rats caused by pasteurella pneumotropica.sixty-one of 2500 f344 rats were observed to have one to three enlarged and firm mammary glands. pasteurella pneumotropica was isolated from all affected mammary glands. it was also routinely isolated from the feces of all cages and from the oral cavity of rats up to 6 weeks old, but not from the oral cavity of rats over 4 months of age. the organism was not isolated from clinically normal lactating mammary glands. histopathological diagnosis of affected glands was chronic necrotizing mastitis.1978682580
[contamination and age as factors in the pathogenesis of atrophic rhinitis (author's transl)].the relationship between contamination with bordetella bronchiseptica or pasteurella multocida and the age of the piglets on the one hand and the pathogenesis of atrophic rhinitis on the other, is discussed. minimal disease-free piglets born and reared on farms on which pigs affected with clinical atrophic rhinitis were present, developed clinical atrophic rhinitis at the age of six weeks. piglets born in the central veterinary institute (cvi) of sows from herds including pigs affected with atro ...1978684734
correlation of microbiological and histological findings in bovine fibrinous pneumonia.in a retrospective morphological and microbiological study, 39 of 55 cases of bovine fibrinous pneumonia were diagnosed as fibrinous pleuropneumonia. twenty-nine of these 39 (74%) were associated with pasteurella hemolytica, but only two cases (5%) with p. multocida. in contrast, of the 16 cases classified as fibrinous bronchopneumonia, one (6%) was associated with p. hemolytica, and nine (56%) with p. multocida. in eight cases mycoplasma and hemophilus somnus were found in association with eith ...1978685079
pasteurella multocida infectious arthritis.pasteurella multocida, a small gram-negative rod, is a domestic animal saprophyte that occasionally causes disease in humans. infectious arthritis may develop from a superficial animal bite or scratch. nine previous cases of infectious arthritis due to this organism have been documented in the literature, and a tenth case is reported here. most patients had recent animal exposure, and half the patients had underlying chronic rheumatoid arthritis. clinical signs of inflammation were consistently ...1978686043
an agglutination test for the detection of bordetella bronchiseptica infection in swine.an agglutination test with the use of formalin-killed antigen of the cell carrying the capsule was developed and used for the detection of antibody in swine naturally infected with bordetella bronchiseptica. under optimum antigen concentration and reaction temperature 210 or 60% of 342 serum samples tested from 42 conventional swine herds were positive for bordetella infection. in contrast, only 34 or 10% of 342 nasal swabs from the same animals were positive for bordetella by culture technique. ...1978688071
the bovine alveolar macrophage. ii. in vitro studies with pasteurella haemolytica.bovine alveolar macrophages were cultured in vitro and challenged with suspensions of live and dead bacteria. these cells showed severe cytotoxic morphological changes and a low rate of phagocytosis after exposure to live pasteurella haemolytica type i was readily phagocytosed and produced only mild cytotoxic changes.1978688077
pasteurella multocida from canine and feline teeth, with a case report of glossitis calcinosa in a dog caused by p. multocida.a case of glossitis calcinosa in a dog caused by pasteurella multocida is reported. swelling of the tongue and reduced appetite were the predominant clinical symptoms. due to latent infections with p. multocida in many species there is a risk of bitewounds being infected with this microorganism. in order to find the carrier-rate of p. multocida samples in canines, teeth and gingiva of 121 dogs and 30 cats were examined bacteriologically, revealing a carrier rates of 55% and 80% respectively. the ...1978693275
live streptomycin-dependent pasteurella multocida vaccine for the prevention of hemorrhagic septicemia.a type b pasteurella multocida was used for the development of a streptomycin-dependent (strd) vaccine. pasteurella multocida r-473, a hemorrhagic septicemia strain, was mutagenized with n-methyl-n'-nitro-n-nitrosoguanidine to increase the likelihood of encountering a strd mutant and was plated on agar containing 400 microgram of streptomycin/ml. replica plating was used to differentiate dependent from resistant colonies. mice and rabbits were vaccinated with a strd mutant and 21 days later, wer ...1978697163
abortion in mice associated with pasteurella pneumotropica.pasteurella pneumotropica was isolated from the uteri, fetuses, lungs, and spleens of aborting swiss carworth mice. male mice in the colony carried p. pneumotropica in pharynges, testes, and seminal vesicles. normal pregnant and nongravid females carried p. pneumotropica in the eye of 1 and in the uteri of 4 of 11. pregnant mice from another colony did not abort when injected with p. pneumotropica. necrotizing and suppurative metritis was found among aborting females with p. pneumotropica infect ...1978701461
isolation of pasteurella aerogenes from the uterus of a rabbit following abortion.pasteurella aerogenes was isolated from the uterus and peritoneal cavity of a rabbit which died 4 days after abortion. histopathologic observations confirmed a bacterial infection. mouse pathogenicity tests indicated that this organism was an opportunistic pathogen that might have been responsible for the stillbirths. the cultural and biochemical characteristics of this isolate were similar to those of the pasteurella aerogenes isolated from swine. this is the first report describing the isolati ...1978703252
[atrophic rhinitis in swine].four 60-day-old pigs were experimentally infected with bordetella bronchiseptica at a state in which the animals were clinicylly normal. a single pig only, killed on the 180th day, presented a slight deflection of septum nasi. morphologically, there were severe dystrophic and necrotic changes in the mucosa of the conchae, the nasal cartilages as well as in the bones. the pathogen was reisolated from two of the pigs. clinical and morphological investigations were carried out also with spontaneous ...1978706148
partial characterization of r-plasmids from pasteurella multocida isolated from turkeys.pasteurella multocida, isolated from turkeys during an outbreak of septicemic disease ("fowl cholera"), was found to be resistant to tetracycline, streptomycin, and sulfonamides. agarose gel electrophoretic analysis of dna from these isolates indicated the presence of extrachromosomal elements. plasmid dna was isolated by cesium chloride-ethidium bromide density centrifugation. escherichia coli was transformed to antimicrobic resistance with this dna. two plasmids were isolated. one of these pla ...1978708012
[pathogenicity of yersinia enterocolitica: a comparison with y. pseudotuberculosis]. 1975765539
[sensitivity of pseudotuberculosis bacteria to colicines]. 1975765690
meningitis and bacteremia caused by pasteurella ureae. report of a case following intracranial surgery.an otherwise healthy 53-year-old woman underwent intracranial surgery for trigeminal neuralgia. one week later she developed meningitis and bacteremia caused by pasteurella ureae and was treated successfully with antimicrobials. this organism is known to colonize the respiratory tract in certain individuals and is an extremely rare cause of meningitis or bacteremia. this is the first reported case of bacteremia in an adult.1978715386
mandibular osteomyelitis in the rabbit. 1978716180
pasteurella multocida infection of broiler chickens. 1978716191
a case of clinical mastitis due to pasteurella multocida. 1978716192
pasteurella multocida as a cause of vomiting and diarrhea in a 4-year-old boy. 1978670843
etiological studies on natural outbreaks of pneumonia in mice. 1978671929
less frequently reported gram-negative fermentative rods.the clinical significance and distinguishing characteristics of less frequently reported gram-negative fermentative rods (pasteurella, yersinia, vibrio, aeromonas and plesiomonas, enterobacter agglomerans, and chromobacterium) are described. increased awareness of these organisms, a knowledge of possible sites in which they cause infection, and identification criteria which will separate them from similar bacteria will prepare the clinical microbiologist for the isolation and identification of t ...1976769548
effect of cholera preventative treatments on reproductive performance of turkey hens.turkey hens were treated with either the clemson university (cu) strain of p. multocida, chlortetracycline, bacterin, or no cholera preventative treatment during the growing period. this was followed by cu vaccination during the production period in all except an untreated control group and resulted in no significant differences (p less than 0.05) in egg production, egg weight, fertility, hatchability, body weight, or feed consumption. best liveability after post-production challenge with p-1059 ...1978674032
clostridium pseudotetanicum bacteremia in a patient with pasteurella multocida conjunctivitis.clostridium pseudotetanicum only once previously has been identified as causing disease. pasteurella multocida has been identified only three times as the cause of purulent conjunctivitis. a very debilitated patient had c. pseudotetanicum bacteremia and p. multocida conjunctivitis from which she recovered only to die of a nosocomial staphylococcus epidermidis septicemia, originating in a site for the administration of intravenous fluids.1978730826
isolation of yersinia (pasteurella) pseudotuberculosis from the palm dove (streptopelia senegalensis).yersinia pseudotuberculosis was isolated from a sick palm dove (streptopelia senegalensis) picked up near a turkey farm in nir-banim, israel. clean birds and a guinea pig inoculated with the isolate died of the infection, or were killed in extremis. y. pseudotuberculosis showing the same cultural characteristics as the original isolate was recovered from these animals. this is the first reported case of this infection from israel.1976769770
outbreaks of waterborne disease in the united states, 1974. 1976772133
evaluation of a new prolonged-release sulfamethazine bolus for use in cattle. 1976772944
clinical and pathologic conditions of female nude (athymic) mice in two conventional maintained colonies.two colonies of female outbred nude (athymic) mice were maintained by conventional standards of husbandry, but with special sanitary methods and segregation from other rodents. a total of 1,526 mice entered the colonies. of these, 802 were untreated and most remained healthy. necropsies were performed on 312 untreated mice that were sick and were killed or died naturally, and the tissues were examined microscopically. clinical and pathologic conditions in the untreated mice included subcutaneous ...1978738946
serological tests as indicators of immunity against pasteurella multocida infection in sheep.five serological tests, i.e. single tube agglutination, doubling dilution tube agglutination, agar agglutination, passive hemagglutination and passive mouse protection tests were evaluated for their efficacy in predicting the fate of vaccinated and unvaccinated sheep on challenge with an ovine strain of pasteurella multocida. the passive hemagglutination test predicted the fate of unvaccinated sheep while the agar agglutination test indicated the immune status of vaccinated sheep.1978743601
[production of l forms of the plague microbe].experiments were conducted in vitro. the process of formation of unstable l-form cultures of pasteurella pestis under the effect of penicillin was studied. a comparatively high frequency of this phenomenon in various strains was demonstrated. a possible role of the l-transformation process in the persistence of the causative agent in the organism of wild animals in endemic foci of infection is put forward.1978747008
[additional studies on the etiology of rhinitis atrophicans in the swine. 3. serological type determination of p. multocida cultures isolated from nasal swabs]. 1978747624
[respiratory enzootics in sheep caused by pasteurella haemolytica].bacteriologically in 25 per cent of the materials taken from lambs, weaned lambs, and adult sheep pasteurella haemolytica was invariably isolated. serologic typing revealed that serotypes a2 and a6 were mostly widespread. the remaining serotypes proved to be encountered. widely occurring were likewise the carriers of pasteurella haemolytica both among the diseased animals and among the normal contacts--30 and 6 per cent, respectively. the serotype of the isolated strains (swab samples) was shown ...1978749330
[use of attenuated mutants of pasteurella multocida strain, pathogenic to calves, in experimental mouse model studies. 4. immunogenicity of selected revertants of temperature-sensitive, streptomycin-dependent mutants as potential vaccine strains].temperature-resistant or streptomycin-independent revertants were isolated from temperature-sensitive or streptomycin-dependent mutants of a pasteurella multocida strain with pathogenicity to calf. the revertants were tested for virulence in mice and for their immunogenicity against wild-strain infection, using 100 times and more of the lethal dose. the following conclusions may be derived from the results thus obtained: 1. most of the fully attenuated streptomycin-independent revertants failed ...1978749742
studies on pasteurella multocida. vi. nature of systemic immunity and analysis of the correlation between levels of immunity induced by various fowl cholera vaccines and protection against challenge.the nature of the systemic immunity induced by various vaccines against fowl cholera disease in turkeys was investigated. used as vaccines were three avirulent strains (cu, m2283, and p1580) of pasteurella multocida administered in the drinking water and a bacterin administered parenterally. a passive hemagglutination test was developed to measure levels of systemic humoral immunity. systemic cell-mediated immune response was assayed by an in vitro immunostimulation microculture system utilizing ...1978749893
characterization of pasteurella multocida isolates from the nares of healthy rabbits with pneumonia.pasteurella multocida was isolated from 42 of the 135 (31%) deep nasal swabs from clinically healthy conventional rabbits supplied by two vendors. the prevalences were significantly different among sex, age, and sources. the females and adults had higher prevalences when compared to males and juveniles, respectively. one vendor's rabbits had a prevalence of 41% while the other had 20%. biochemically, only 24% of the 42 isolates decarboxylated l-ornithine, and 55% produced indol. all isolates wer ...1978750729
[heterogeneity of the population of pseudotuberculosis microbe cultures].use of the method of oblique illumination of the colonies permitted to detect four variants of pseudotuberculosis microbe differing by the character of fluorescence, and also by virulence, toxicity and immunogenicity. strains isolated from sick persons, carriers and rodents were characterized by polychromatic character of fluorescence of the colonies, whereas strains isolated from the external environment were monochromatic. since colonies with a different fluorescence had different biological p ...1976785879
[far eastern scarlatina-like fever (human pseudotuberculosis)]. 1976785891
subcutaneous vaccination of chickens with a live, avirulent pasteurella multocida, vaccine.the immunogenic responses to various routes of vaccination of broiler-type chickens to the clemson university strain of pasteurella multocida were evaluated. broilers were vaccinated at 9 or 10 weeks of age using the oral (drinking water), palatine cleft, ocular, or subcutaneous injection routes. all birds were challenged at 11 or 12 weeks of age with virulent x-73 strain of p. multocida by the palatine cleft method. the degree of efficacy of the various vaccination routes differed among three e ...1978751031
the influence of preconditioning on plasma corticosteroid levels, rectal temperatures and the incidence of shipping fever in beef calves. 1976788887
determination of corticosterone concentration in plasma of turkeys using raioimmunoassay.a method of determining corticosterone concentration in turkey plasma was developed using radioimmunoassay. compared to fluorometric analysis and competitive protein-binding radioassay, this method had the following advantages: 1) results were consistent, 2) the method was simple and rapid to perform, 3) only 20 lambda of plasma was required, 4) all procedures were performed using the same tube except for counting, and 5) unknown and standard samples were treated identically. the coefficient of ...1978751044
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