Publications

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comparison of cell-mediated immune reactions in sympathetic and phacogenic ophthalmia with reactions in uveitis of other origin.cell-mediated immunity was studied in three cases of genuine sympathetic ophthalmia, i.e. in cases without lens involvement. in control experiments, lymphocyte transformation tests (uptake of 3h-thymidine) and leukocyte migration inhibition tests (soborg-bendixen) gave similar results for six normal persons, six patients with uveitis and two cases of phacogenic ophthalmia. in contrast, two cases of genuine sympathetic ophthamlia, namely those with recent enucleation, showed a significantly incre ...20051082540
[case of pie (pulmonary infiltrate with eosinophilia) syndrome caused by candida]. 20154477881
the case for the proposed increase in iron enrichment of flour and wheat products. 20155023246
[therapy monitoring of regional chemotherapy by magnetic resonance spectroscopy]. 20082474953
prostatic carcinoma. 1998106277
tetralogy of fallot in adults. 199991440
multiple forms of phosphofructokinase in animals from the phylum chordata. 2002134863
electrocardiographic changes under moderate hypoxia. 2005546723
inspiring nursing students to mobilize communities in nepal.in 1987 nurse educators in nepal implemented a revised certificate nursing curriculum oriented toward primary health care (phc) and a bachelor of community health nursing (chn) curriculum with emphasis on leadership in phc. as both curricula included practical experience for nursing students in the community, the teachers had to strategize how to maximize both the students' learning and their contribution to community health. below, how the educators encouraged reluctant students to not only par ...20082249925
dice: nonclinical causes of overtreatment. 20102916481
[duodenal gastrinoma. description of a clinical case]. 20113231322
the piriformis syndrome. 20123390766
[a comparative study. the older person too is an individual]. 20133850215
pseudosarcoma of the skin. an electron microscopic study and comparison with the fine structure of spindle-cell variant of squamous carcinoma. 20164819223
the kidney in sickle cell disease ii: the kidney and sickling phenomenon. 20164805648
[conservative treatment of injuries of the liver]. 20143911104
[preparation and purification of anti-ferritin, anti-cytochrome b 5 hybrid antibodies]. 20144122927
the loyalty of the occupational physician. 1962279370
rampant caries and its management. part 2. clinical management. 1962279347
homogeneous immunoglobulins in the serum of irradiated and bone marrow reconstituted mice: the role of thymus and spleen.the influence of thymectomy and splenectomy on the frequency and class distribution of homogeneous immunoglobulins (h-ig) in serum was studied in lethally irradiated (dba/2 x c57bl/rij)f1 mice reconstituted with syngeneic bone marrow. during four follow-up periods in the first 9 months after transplantation, the sham-operated controls and splenectomized animals developed transient h-ig in an average frequency of 14.2 and 15.7% respectively. there were no marked differences in the incidence of h- ...2004387578
rocky mountain spotted fever--united states, 1987. 20113131657
[enterostoma therapy--a pilot course in the essen education center of the german nursing association]. 20113127632
endotracheal resuscitation of preterm infants at birth. 20133688937
a novel integrin function in innate immunity from chinese mitten crab (eriocheir sinensis).integrins belong to a superfamily of conserved α β heterodimeric cell surface receptors that have critical function in cell migration, differentiation, and survival. in this study, an integrin called esintegrin was identified from chinese mitten crab eriocheir sinensis. esintegrin cdna is 4415 bp long with a 2457 bp open reading frame that encodes an 818 amino acid protein. esintegrin contains a signal peptide, an integrin beta subunit (n-terminal portion of extracellular region) inb domain, an ...201526004499
function of two novel single-crd containing c-type lectins in innate immunity from eriocheir sinensis.c-type lectin is one of the pattern-recognition proteins of the non-self-innate immune system in invertebrates. in this study, two novel c-type lectin cdnas (esctl1 and esctl2) of eriocheir sinensis were cloned and characterized. esctl1 has 169 amino acids, whereas esctl2 has 164 amino acids. these two lectins contain one carbohydrate-recognition domain. phylogenetic analysis showed that esctl1 and esctl2 were not clustered with other reported lectins from crabs. esctl1 and esctl2 were expressed ...201424561128
an ldla domain-containing c-type lectin is involved in the innate immunity of eriocheir sinensis.c-type lectins (ctls) have crucial functions in recognizing and eliminating pathogens in innate immunity. this study identified a novel low-density lipoprotein receptor class a (ldla) domain-containing ctl, designated as esctldcp, from the chinese mitten crab eriocheir sinensis. the esctldcp cdna is 1258 bp long, with a 975 bp open reading frame that encodes a 324-amino acid protein. esctldcp contains a signal peptide, an ldla, and a single c-type lectin-like domain. esctldcp was only expressed ...201424140432
construction of a bioreporter by heterogeneously expressing a vibrio natriegens reca::luxcdabe fusion in escherichia coli, and genotoxicity assessments of petrochemical-contaminated groundwater in northern china.here, we constructed an escherichia coli reca::luxcdabe bioreporter for genotoxicity assessments. the reca promoter was cloned from the marine bacterium vibrio natriegens. this bioreporter showed a dose-response relationship following induction by mitomycin c, and other pollutants or environmental samples could be calculated as mitomycin c equivalents, which provided a way to quantitatively compare the genotoxicities of different environmental samples. this bioreporter was used to evaluate the g ...201627258332
sulfated phenolic acids from dasycladales siphonous green algae.sulfated aromatic acids play a central role as mediators of chemical interactions and physiological processes in marine algae and seagrass. among others, dasycladus vermicularis (scopoli) krasser 1898 uses a sulfated hydroxylated coumarin derivative as storage metabolite for a protein cross linker that can be activated upon mechanical disruption of the alga. we introduce a comprehensive monitoring technique for sulfated metabolites based on fragmentation patterns in liquid chromatography/mass sp ...201526188914
sulfation mediates activity of zosteric acid against biofilm formation.zosteric acid (za), a metabolite from the marine sea grass zostera marina, has attracted much attention due to its attributed antifouling (af) activity. however, recent results on dynamic transformations of aromatic sulfates in marine phototrophic organisms suggest potential enzymatic desulfation of metabolites like za. the activity of za was thus re-investigated using biofilm assays and simultaneous analytical monitoring by liquid chromatography/mass spectrometry (lc/ms). comparison of za and i ...201525915112
the mosaic accessory gene structures of the sxt/r391-like integrative and conjugative elements derived from vibrio spp. isolated from aquatic products and environment in the yangtze river estuary, china.the emergence, resurgence and spread of human food-borne pathogenic vibrios are one of the major contributors to disease burden and mortality particularly in developing countries with disputable sanitary conditions. previous research on pathogenic vibrio cholerae and vibrio parahaemolitycus derived from clinical samples has proposed links between acquisition of virulence and multiple drug resistance traits and intercellular transmissibility of mobile genetic elements in the environment. to date, ...201324074349
genes similar to the vibrio parahaemolyticus virulence-related genes tdh, tlh, and vscc2 occur in other vibrionaceae species isolated from a pristine estuary.detection of the human pathogen vibrio parahaemolyticus often relies on molecular biological analysis of species-specific virulence factor genes. these genes have been employed in determinations of v. parahaemolyticus population numbers and the prevalence of pathogenic v. parahaemolyticus strains. strains of the vibrionaceae species photobacterium damselae, vibrio diabolicus, vibrio harveyi, and vibrio natriegens, as well as strains similar to vibrio tubiashii, were isolated from a pristine salt ...201424212573
vibrio natriegens as a fast-growing host for molecular biology.a rapidly growing bacterial host would be desirable for a range of routine applications in molecular biology and biotechnology. the bacterium vibrio natriegens has the fastest growth rate of any known organism, with a reported doubling time of <10 min. we report the development of genetic tools and methods to engineer v. natriegens and demonstrate the advantages of using these engineered strains in common biotech processes.201627571549
[screening and identification of a bacterium capable of converting agar to neoagaro oligosaccharides].to screen and identify a bacterium capable of converting agar to neoagaro oligosaccharides.201526762025
universally improving effect of mixed electron donors on the co₂ fixing efficiency of non-photosynthetic microbial communities from marine environments.the universality of improved co₂ fixing upon the addition of mixed electron donors (meds) composed of na₂s, no₂(-), and s₂o₃(2-) to non-photosynthetic microbial communities (npmcs) obtained from 12 locations in four oceans of the world was validated. the co₂ fixing efficiencies of npmcs were universally enhanced by med compared with those obtained using h₂ alone as electron donor, with average increase of about 276%. an increase in microbial inoculation concentration could increase the net amoun ...201425108727
draft genome sequence of the fast-growing bacterium vibrio natriegens strain dsmz 759.vibrio natriegens is a gram-negative bacterium known for its extremely short doubling time. here we present the annotated draft genome sequence of vibrio natriegens strain dsmz 759, with the aim of providing insights about its high growth rate.201323969053
draft genome sequence of the fast-growing marine bacterium vibrio natriegens strain atcc 14048.vibrio natriegens bacteria are gram-negative aquatic microorganisms that are found primarily in coastal seawater and sediments and are perhaps best known for their high growth rates (generation time of <10 min). in this study, we report the first sequenced genome of this species, that of the type strain vibrio natriegens atcc 14048, a salt marsh mud isolate from sapelo island, ga.201323929482
specific atp and specific oxygen uptake rate in immobilized cell aggregates: experimental results and theoretical analysis using a structured model of immobilized cell growth.in this work the quality and activity of immobilized beneckea natriegens have been measured using specific atp (satp) [mg (atp) g(-1) (dry biomass)] and specific oxygen uptake rate (sour) [mg o(2) g(-1) (dry biomass) h(-1)]. the cells were grown in a 3 l three phase air lift bioreactor (tpalb) and were immobilized on diatomaceous earth (silica) support particles; sterile conditions were employed during the experiment, with n-propanol as the sole carbon source. two sets of experiments were perfor ...199718636576
adenylate energy charge during batch culture of beneckea natriegens.the value of the adenylate energy charge, i.e. ([atp] + 1/2[adp])/([atp] + [adp] + [amp]), during batch culture of beneckea natriegens remained relatively constant during the exponential and early stationary phases of the growth cycle. during exponential growth the intracellular atp content remained constant, the amount of atp in the culture increasing proportionally with growth; these conditions were unaltered during growth in the presence of added cyclic amp. on cessation of growth, significan ...197713148
the effect of rate of respiration on sensitivity to cyanide and carbon monoxide in beneckea natriegens grown in batch and continuous culture. 19761278391
molar growth yields, respiration and cytochrome patterns of beneckea natriegens when grown at different medium dissolved-oxygen tensions.the effect of medium dissolved-oxygen tension on the molar growth yield, respiration and cytochrome content of beneckea natriegens in chemostat culture (d 0-37 h-1) was examined. the molar growth yield (y), the specific rate of oxygen (qo2) and glucose consumption, and the specific rate of carbon dioxide evolution were independent of the dissolved-oxygen tension above a critical value (greatest than 2 mmhg). however, the potential respiration rate increased with reduction in the dissolved-oxygen ...19751194892
multiplex genome editing by natural transformation (mugent) for synthetic biology in vibrio natriegens.vibrio natriegens has recently emerged as an alternative to escherichia coli for molecular biology and biotechnology, but low-efficiency genetic tools hamper its development. here, we uncover how to induce natural competence in v. natriegens and describe methods for multiplex genome editing by natural transformation (mugent). mugent promotes integration of multiple genome edits at high-efficiency on unprecedented time scales. also, this method allows for generating highly complex mutant populati ...201728571309
environmental impact of tributyltin-resistant marine bacteria in the indigenous microbial population of tributyltin-polluted surface sediments.we compared the tbt-resistant ability of resting cells prepared from isolates that formed colonies on nutrient agar plates containing 100 µm tributyltin (tbt) chloride, such as photobacterium sp. tky1, halomonas sp. tky2, and photobacterium sp. ngy1, with those from taxonomically similar type strains. photobacterium sp. tky1 showed the highest ability among those three isolates. the number of surviving photobacterium sp. tky1 cells was hardly decreased after 1 h of exposure to 100 µm tbtcl, rega ...201728659560
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