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acetylated methylmannose polysaccharide of streptomyces griseus. locations of the acetyl groups.the positions of esterification of the 4 to 5 acetyl residues in the acetylated methylmannose-containing polysaccharide from streptomyces griseus have been established by the methyl replacement technique, wherein ester substituents are specifically replaced with methyl ether substituents. the newly incorporated methyl groups were distinguished from 3-o-methyl groups by the use of polysaccharide containing radioactively labeled endogenous methyl groups. the positions of methyl group localization ...1979107171
dietary protein, aryl hydrocarbon hydroxylase and chemical carcinogenesis in rats. 1979107295
effects of dietary composition on somatomedin activity in growing rats. 1979107298
effects of entrapment in liposomes on the distribution, degradation and effectiveness of methotrexate in vivo. 1978100041
the effects of foveal prestriate and inferotemporal lesions on matching to sample behaviour in monkeys. 197899683
single-antibiotic therapy for streptococcal endocarditis.ninety-nine patients treated with penicillin g potassium, cephalothin sodium, or vancomycin hydrochloride were studied to evaluate single-drug therapy for nonenterococcal streptococcal endocarditis. eighty-six patients survived; of these, 66 received penicillin alone. the maximum serum bactericidal titer obtained at the expected nadir of serum antibiotic concentration was 1:8 or greater in 70 (95%) of the 74 patients studied. no relapse occurred among the 66 patients treated wih penicillin. only ...1979107335
partial purification of heat-labile hemolysin from pseudomonas aeruginosa. 1978107353
heat-labile enterotoxigenic escherichia coli infections in new arrivals at subic naval base, the philippines. 1979107483
[preparation of extracellular ribonuclease from bacillus subtilis].the paper describes a method for isolating alkaline ribonuclease from the culture liquid bacillus subtilis kp 349 which involved: submerged cultivation of the producer on complex and synthetic nutrient media with optimized rnase activity, acid treatment of the total culture liquid, and filtration through perlite. further treatment may include either spray drying of the culture liquid filtrate or its concentration in a vacuum evaporator, dialysis of the concentrate against distilled water, and d ...1978107517
prolongation of islet allograft survival following in vitro culture (24 degrees c) and a single injection of als.isolated rat islets remain morphologically and functionally intact during a 7-day period of in vitro culture at 24 degrees c. in vitro culture of islets at 24 degrees c for 7 days prior to transplantation, in conjunction with a single injection of antiserum to lymphocytes into the diabetic recipient, results in islet allograft survival of 100 days when the islets are transplanted across a major histocompatibility barrier.1979107588
frequency and fate of human renal allografts contaminated prior to transplantation.bacterial cultures were done from donor ureter and/or graft perfusion fluid on 92 of 112 patients who had renal transplantations during 1977. three samples of perfusion fluid and 14 samples of donor ureter contained bacteria. in nine cases there was a gram-positive organism, and in 10 cases a gram-negative rod was (among) the contaminant(s). there was no difference in the rate of graft survival, patient survival, or in the frequency of major postoperative complications between the two groups. on ...1979107605
postnatal development of resistance against infection in an experimental model.the postnatal development of resistance against infection was monitored by the treatment of juvenile mice with a virulent strain of listeria monocytogenes. it could be shown that until day 10 after birth, young mice succumbed to an infection with even minimal doses of bacteria. between day 15 and 30, the resistance against infection gradually increases until the rather constant level of grown-up animals is reached (fig. 1). juvenile mice that survive the primary infection are able to build up a ...1978107682
[dynamics of changes in the surface of normal cultivated rat cells after a single exposure to the carcinogen 7,12-dimethylbenz(a)anthracene].changes in the cell surface after a single treatment with 7,12-dimethylbenz(a)anthracene (dmba) of newborn rat carcass in cell culture have been studied by means of the agglutination reaction with concanavalin a. dmba was shown to cause alterations in the cell surface. at 0.5 mkg/ml of dmba, the difference in agglutinability of treated and untreated cells persists for 30 days. at 0.1 mkg/ml of dmba, the agglutinability of drug-treated and control cells was similar on the 4th day after removal of ...197898876
stability and viability of neisseria gonorrhoeae in various solutions and buffers.the stability and viability of neisseria gonorrhoeae wp (t4) was tested in a variety of buffers and solutions, many of which are commonly used in gonococcal research. each solution was tested at room temperature for its ability to maintain stability and viability of gonococci in concentrated suspensions and to maintain viability of gonococci in dilute suspensions. the 14 buffers and solutions tested could be divided into four groups based upon these criteria. only a few solutions satisfied all t ...1979107855
two functional types of neurons in the superficial layers of monkey superior colliculus. 1978107871
differentiation of mycobacteria by "in vivo" and "in vitro" delayed hypersensitivity reactions.guinea pigs were sensitized with heat killed m. tuberculosis, m. kansasii, m. scrofulaceum, and m. avium-intracellulare. purified protein derivatives (ppds) prepared from each of these organisms were tested for delayed type hypersensitivity by lymphocyte transformation, macrophage migration, and mantoux type skin sensitivity tests. the homologous reactions were consistently more intense than heterologous reactions in all three procedures. the skin test procedure was more sensitive than either in ...197898814
spinal cord evaluation by cortical evoked responses.in ten monkeys, selective segmental lesions of the dorsal columns at the upper thoracic and middle cervical levels resulted in almost total attenuation of the cortical evoked potential responses to peripheral nerve stimulation. conversely isolated segmental dorsal column preservation showed intact transmission of the evoked responses at rostral spinal cord, nucleus ventralis posterior lateralis, and cortical levels. responses recorded from the intralaminar thalamic nuclei in the region of nucleu ...1979107931
induction of reaginic (ige) gonococcal antibodies in the rat by a common antigen of neisseria gonorrhoeae.an antigen (zab) common to neisseria gonorrhoeae was prepared by stepwise elution of a crude gonococcal antigen (za) from columns of diethylaminoethyl cellulose employing 0.02 m phosphate buffers, ph 7.6, containing increasing concentrations of sodium chloride. rats immunized with zab produced reaginic (ige) antibody which cross-reacted with za prepared from eight gonococcal strains by the passive cutaneous anaphylaxis (pca) test. heating of the sera at 56 degrees c for 4 h destroyed the pca act ...1979108009
[in vitro biosynthesis of beta-lipotropin in brain tissue].we have recently developed methods to identify biosynthetized beta-endorphin and beta-lipotropin (beta-lph) following incubation of rat pars intermedia with radioactive amino acids. we used the same approach for rat brain tissue. in the striatum we found a peptide similar to beta-lph while its identification in hypothalamus was less positive. this is the first demonstration of such biosynthesis and it could well be an important step in determining the biosynthetic patterns of cerebral endorphins ...1979108023
[antiarrhythmic properties of 3-(2-hydroxy-3 isopropylamino-propoxy)-3 phenyl-2 isoindolinone-1, (rs, sr) in the dog].in the dog, 3-(2-hydroxy-3 isopropylamino-proxy)-2-phenyl-1-isoindolinone (rs, sr) possesses an anti-arrhythmic activity similar to that of quinidine but at dose levels 2 to 6 times lower than in the case of the latter compound. furthermore, in contrast to quinidine, at the dose levels where the antiarrhythmic activity is well observed, the compound is devoid of hypotensive activity and of depressive action on cardiac contractility. the first clinical studies of this compound have shown its usef ...1979108025
[infection of alouatta carayá (mono aullador) by junín virus]. 197898811
electron-microscopic identification of axonal initial segments belonging to interneurons in the dorsal lateral geniculate nucleus of the monkey. 197898733
who pays health costs of alcohol and tobacco? 197898713
fascioloides magna: development in selected nonruminant mammalian hosts. 1979108129
inhibition of 7,12-dimethylbenz[alpha]anthracene-induced mammary tumorigenesis in rats by a synthetic protease inhibitor, n,n-dimethylamino-(p-(p'-guanidinobenzoyloxy)) benzilcarbonyloxyglycolate.oral administration of n,n-dimethylamino-(p(p'-guanidinobenzoyloxy))-benzilcarbonyloxy glycolate depressed induction of breast tumors in rats by a single intravenous injection of 7,12-dimethylbenz[alpha]anthracene. the latent period was delayed in the group fed on a diet supplemented with n,n-dimethylamino-(p(p'-guanidinobenzoyloxy))benzilcarbonyloxy glycolate. administration of this compound for 40 days after 7,12-dimethylbenz[alpha]anthracene also significantly reduced the average weight of tu ...1978108169
observations on acute gastric dilatation in nonhuman primates.in the years 1967-1977 we diagnosed 23 cases of acute gastric dilatation in monkeys. fourteen of these animals were macaca mulatta, five macaca fascicularis, and one each of macaca nemestrina, aotus trivirgatus, saimiri sciureus, and colobus guereza. fourteen of the animals were males, nine were females, and all were adults or subadults. mortality was 78% (18 of 23 animals). thirteen of the animals had received on anesthetic, immobilizing, or tranquilizing drug 1-2 days before developing acute g ...197898666
a microagglutination test for yersinia enterocolitica infection: recognition of multiple serotypes in experiments with stained suspensions of serotype o5,27.when suspensions of yersinia enterocolitica were stained with triphenyl-tetrazolium chloride (ttc) their antigenic specificity, as determined by tube and microtitre-plate agglutination tests, was altered. thus, a ttc-stained suspension of serotype o5,27 detected antibodies to nine o serotypes of y. enterocolitica in sera from experimentally infected animals but did not cross-react with antisera to organisms of five other unrelated genera including brucella. the same suspension did, however, cros ...197898635
identification of low chlorinated biphenyls in human milk by gas chromatography--mass spectrometry.trichlorobiphenyl and tetrachlorobiphenyls in human milk were analysed by gas chromatography--mass spectrometry and mass fragmentography using silicone ov-1 and apiezon l grease as stationary phases. low-chlorinated biphenyls had been considered to be excreted rapidly from the body, but in this work quantities of tri- and tetrachlorobiphenyls amounting to approximately 30% of the total of polychlorinated biphenyls (pcbs) accumulated in the milk were identified. this result is important in relati ...197898535
altered mrna metabolism in ribonuclease iii-deficient strains of escherichia coli.the metabolism of mrna from the lactose (lac) operon of escherichia coli has been studied in ribonuclease (rnase) iii-deficient strains (rnc-105). the induction lag for beta-galactosidase from the first gene was twice as long, and enzyme synthesis was reduced 10-fold in one such mutant compared with its isogenic rnc+ sister; in the original mutant strain ab301-105, synthesis of beta-galactosidase was not even detectable, although transduction analysis revealed the presence of a normal lac operon ...197898520
age as a modifying factor of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in the lewis rat. 1979108227
pregnant mare serum gonadotropin. purification and physicochemical, biological, and immunological characterization. 1979108273
neonatal gonococcal orogastric contamination. 197897404
transient pseudomonas bacteremia in a heroin addict. resemblance to right-sided endocarditis. 197897401
incorporation of amino acids by isolated submitochondrial fractions of lactating goat mammary gland in vitro.incorporation of amino acids by mitochondria and its subfractions from mammary gland of the goat during lactation was studied in vitro. assessment of distribution of radioactivity incorporated by intact mitochondria into its subfractions revealed maximum specific activity in the inner membrane. during lactation the inner membrane of mitochondria exhibited further stimulation in such incorporation. matrix was the next active fraction whereas outer membrane and peripheral space had negligible radi ...1978101564
growth and food intake of prematurely weaned rats: effect of cortisone and thyroxine injection during the suckling period. 1979108369
effect of n-trifluoroacetyl derivatives of amino acids and amino acid analogs on microbial antitumor screen.eighteen trifluoroacetyl derivatives of amino acids and of amino acid analogs were prepared and tested for growth-inhibitory activity using a lactobacillus casei system as a prescreen for antitumor activity. of the compounds tested, the trifluoroacetyl derivatives of o-, m-, and p-fluorophenylalanine and of beta-3-thienylalanine showed modest activity; trifluoroacetyl derivatives of phenylalanine and of beta-2-thienylalanine showed marginal activity. the activity exhibited by the active trifluor ...1979108385
comparison of ketmine with the combination of ketamine and xylazine for effective anesthesia in the rhesus monkey (macaca mulatta).the addition of xylazine to ketamine hydrochloride was found to enhance analgesia, anesthesia, and muscle relaxation in rhesus monkeys. at 0.10 ml/kg body weight, this combination provided adequate anesthesia for such procedures as cisternal puncture, lumbar spinal puncture, insertion of urinary catheters, finger amputations, and tattooing. the combination of ketamine and xylazine did depress the heart rate, respiration rate, and body temperature more than the administration of ketamine alone. t ...1978108468
neurofibrillary pathology: current status and research perspectives.the neurofibrils seen in the light microscope are shown, by electron microscopy, to be heterogeneous structures, formed of neurotubules and neurofilaments. a variety of pathological conditions (especially, presenile and senile dementia (are characterized by the presence of neurofibrillary tangles, formed either of paired helical filaments or of single filaments. the morphology, distribution and biochemistry of these various fibrillary structures is reviewed. particular attention is devoted to th ...1979108483
[anti-neisseria meningitidis antibodies, groups a and c, in individuals from urban and rural regions of argentina]. 1978108502
immobilization of pyridoxal 5'-phosphate and pyridoxal 5'-phosphate-dependent enzymes on sepharose. 1979108513
isolation of an influenza virus subtype hav4navl from a budgerigar. 1979108521
aflatrem, the tremorgenic mycotoxin from aspergillus flavus. 1979108599
aphasia: the sole manifestation of focal status epilepticus.aphasia was the sole manifestation of focal status epilepticus in a man with an old left frontal contusion. the diagnosis was made by electroencephalogram (eeg), and the attack was terminated by anticonvulsant medication.1979108612
response of periapical pathosis to endodontic treatment in monkeys.response of induced periapical lesions in monkeys to a conventional endodontic technique was investigated at varying periods ranging from 15 to 365 days after treatment. the findings indicate that response to treatment is influenced by the extent of the root canal filling, the time lapse between treatment and death, and the presence or absence of bacteria in the apical portion of the canal.1979108648
[new species of microsporidians (microsporidia, nosematidae) from horsefly larvae in the ukraine].a new species of microsporidians, stempellia lairdi sp. n., was found in larvae of tabanus autumnalis l. from ukraine. it affects the muscular tissue and haemolymph of horse fly larvae. spores of the species are oval, egg-shaped, 1.8--7.6 x 1.2--3.8 mu in size. the species is pathogenic and causes the mortality of infected larvae.1979108652
one-carbon metabolism in methanogenic bacteria: analysis of short-term fixation products of 14co2 and 14ch3oh incorporated into whole cells.methanobacterium thermoautotrophicum, m. ruminantium, and methanosarcina barkeri were labeled with 14co2 (14co2 + h14co3- + 14co32-) for from 2 to 45 s. radioactivity was recovered in coenzyme m derivatives, alanine, aspartate, glutamate, and several unidentified compounds. the properties of one important structurally unidentified intermediate (yellow fluorescent compound) displayed uv absorbance maxima at ph 1 of 290 and 335 nm, no absorbance in the visible region, and a fluorescence maximum at ...1978101522
tumor-host responses to various nutritional feeding procedures in rats.parenteral and enteral nutrition are being used as adjuncts to cancer therapy. a liquid diet formulation containing a 27% solution of glucose and 3.9% crystalline amino acids with electrolytes and vitamins was given continuously for a week via parenteral (iv), and via intragastric (ig) routes and also was given ad libitum via the oral or per os (po) route to groups of buffalo rats with and without a morris no. 7777 transplantable hepatoma to find out how these feeding procedures affect tumor-hos ...1979107299
[delayed implantation and early developmental defects in the mouse caused by pcb: 2,2'-dichlorobiphenyl (author's transl)].pregnant mice administered per os during the days 1--3 (plug day = day 0) post conception (p.c.) with 375 mg 2,2'-dichlorobiphenyl/kilograms/day revealed on day 18 p.c. increased number of resorptions and doses up from 500 milligrams/kilograms/day led to a substantial retardation of the prenatal development. based on the investigations during the early development it is concluded, that retardation of the fetus is caused by a delayed implantation. it is assumed, that increased resorption is due t ...1978100080
the effects of alcohol on agonistic behavior in the telomian dog.the study analyzed the effects of alcohol on agonistic behavior in three independent social systems, each compromised of two male and one female telomian dog. three dose levels were used: 0, 0.8, and 1.6 g/kg body weight of absolute alcohol diluted to 20%. observations were made when none, one (top, middle or low ranking), or all dogs in a system received a given treatment. at the 0.8 g/kg level, low ranking dogs showed an increased frequency of attacks and bone possession time, while top and mi ...1979108707
pseudomonas endocarditis. 1979107332
dietary modification of amphetamine stereotyped behaviour: the action of tryptophan, methionine, and lysine.rats fed diets high in tryptophan, methionine, and tryptophan plus methionine or lysine were subsequently injected with 10 mg/kg d-amphetamine. the amount of amphetamine-induced stereotyped behaviour observed varied as a function of the dietary addition, with methionine showing the greatest difference to controls, and lysine the least. whole brain catecholamine levels and 5-hydroxytryptamine levels also showed amino acid-specific changes.1979108724
enhanced 5-hydroxytryptamine-mediated behavioural responses in rats following repeated electroconvulsive shock: relevance to the mechanism of the antidepressive effect of electroconvulsive therapy.treatment of rats with one electroconvulsive shock (ecs) per day for 10 days enhanced the hyperactivity syndrome produced by administration of tranylcypromine (10 mg kg-1) and l-tryptophan (50 mg kg-1) given 24 h after the final shock. similar enhancement was seen whether the shock was alternating sinusoidal or direct current (fractionated), whether it was given through unilaterally or bilaterally placed electrodes and whether or not a neuromuscular blocking agent (fazadinium) was used. five sho ...1979108733
uv versus chemical polymerization of glycol methacrylate (gma) in enzyme histochemistry.the influence of the mode of polymerization of gma on the enzyme activities of differently fixed rat livers was studied. it was found that with increasing time of uv-polymerization several enzyme activities were inhibited whereas chemical polymerization was comparatively less harmful. the histochemical reactivity of substrates such as glycogen was not impaired by the mode of polymerization, which is in contrast to the increased basophilia of dna and rna after uv-polymerization.1978107707
"routine."--a practice to be abjured. 1979110537
lethal effect of protamine and histone on competent bacillus subtilis cells. inhibition of genetic transformation by protamine in sublethal concentration.under experimental conditions of genetic transformation, protamine and total histone were bactericidal for bacillus subtilis cells. the abilities to cause lethality were very similar for both, either protamine or histone, with no antagonistic effects amongst these natural polycations. with both basic proteins acting simultaneously the enhancement was higher than a summation of the separate lethal effects. sublethal concentration of protamine added at the beginning of transformation time, produce ...1979111002
hallucinogen-induced rotational behavior in rats. 1979111284
evaluation of high-protein supplements in children with protein energy malnutrition.the present study was designed to test the comparative efficacy of cow's milk, a protein, vitamin and mineral mixture (pvm) and soybean textured vegetable protein (somos) as supplements to maize meal porridge in the dietary treatment of children with protein energy malnutrition (pem). each diet was designed to provide approximately 480 kj/kg with 2 protein/kg from the test protein, and 1,8 g protein/kg from maize. response to treatment was measured by loss of oedema, subsequent weight gain, rate ...1979111358
cerebellar cortical atrophy in an adult japanese macaque. 1979111404
lethal effects of 32p decay on transfecting activity of bacillus subtilis phage phi e dna. 1979111411
a radial immunodiffusion method for the measurement of rat fibrinogen and fibrin degradation products.the present report describes a technique for the production of monospecific rabbit antiserum to rat fibrinogen and its use in a quantitative radial immunodiffusion assay for measurement of rat fibrinogen and fibrin degradation products. it is a suitable technique for measurement of these parameters in small samples which can be repeatedly obtained from animals the size of rats.1979111420
albumin-coated amberlite xad-7 resin for hemoperfusion in acute liver failure. part i: adsorption studies.platelets adhere to most foreign surfaces. as a result, polymers and albumin have been suggested as possible coatings to improve the blood compatibility of such surfaces. amberlite xad-7 has a high affinity for human serum albumin (hsa) and several protein-bound toxic metabolites. in the present study it is shown that hsa can be tightly bound to amberlite xad-7 without the use of chemical coupling agents. optimal binding was achieved at ph 5.0 and the adsorption conforms to langmuir's isotherm. ...1979107929
substrate-labeled fluorescent immunoassay for phenytoin in human serum.a homogeneous substrate-labeled fluorescent immunoassay has been applied to the measurement of phenytoin concentrations in human serum. we coupled a fluorogenic enzyme substrate, galactosyl-umbelliferone, covalently to a derivative of phenytoin. under assay conditions, this drug-substrate conjugate was nonfluorescent but became fluorescent upon hydrolysis catalyzed by bacterial beta-galactosidase. when antibody to phenytoin is bound to the drug-substrate conjugate, it is inactive as an enzyme su ...1979108033
immunoelectrophoretic studies on human small intestinal brush border proteins. a quantitative study of brush border enzymes from single small intestinal biopsies.a method for measuring brush border membrane enzymes from small intestinal biopsies by crossed immunoelectrophoresis is presented. the use of a brush border specific antiserum made isolation of the brush border membrane before analysis unnecessary. this prevented loss of material which, together with inactivation of enzymes, was a limiting factor in previous studies of brush border enzymes from peroral biopsies. in 58 biopsies from patients without gastrointestinal disorders a close correlation ...1979108036
morphology and morphogenesis of a new paramyxovirus (pmv 107).the morphology of the virions and nucleocapsids of paramyxovirus 107 (pvm 107) and the replication of the virus were investigated by electron microscopy. the virions and nucleocapsids exhibited the same structural properties as other paramyxoviruses. nuclecapsids were found in the nucleus and cytoplasm of infected bovine embryonic lung (bel) cell cultures. a similar situation has been described for the morbilliviruses measles, sspe, distemper and rinderpest. alignment of nucleocapsids beneath th ...1979113501
sensitization of myelinated nociceptive afferents that innervate monkey hand. 1979115969
effect of dopamine on renal blood flow of baboon in endotoxin shock.renal vasodilation observed in canine endotoxemia did not occur during endotoxin shock in the baboon: in fact, renal artery blood flow was markedly reduced. infusion of dopamine in the baboon restored the renal artery blood flow.197898752
epilepsy, attentiveness and consciousness: recent contributions from behavioral and physiological investigations. a summary and commentary. 1978108075
folacin deficiency and requirement in the squirrel monkey (saimiri sciuresus).acute folacin deficiency was studied in eight young squirrel monkeys (saimiri sciureus). half of the animals were fed a semipurified deficient diet (no added folic acid) and half were fed a control diet (0.84 mg of added folic acid per kilogram of dry diet). monkeys fed the deficient diet lost weight and suffered from diarrhea and dehydration leading to the death of one of the animals after 6 weeks. folacin deficiency also was studied in six older animals fed diets containing varying levels of a ...1979116540
evaluation of the moving intermediate zone concept for determing susceptibility of pseudomonads to gentamicin by the standardized disk agar-diffusion test.the usefulness of the moving intermediate zone concept for improving the performance of the standardized disk agar-diffusion test in measuring susceptibility of the fluorescent group of pseudomonads to gentamicin was studied. for this purpose, a 3-mm moving intermediate zone lying --3 mm and --6 mm below that measured for the quality control microorganism pseudomonas aeruginosa, atcc 27853, and a wider moving intermediate zone lying --2 mm and --7 mm below that for the quality control microorgan ...1979116543
complement in tears from normal humans.tears from ten normal persons were used in hemolytic assays to test for activity of total hemolytic complement (tested in all ten subjects), activities of each of the nine complement components (tested in two subjects), and activity of the alternate pathway (tested in two subjects). a modified radial-immunodiffusion method was used to confirm the presence of c3 and c4 complement proteins in the tear samples from all ten subjects. factor b protein was detected in tears from two of four normal sub ...1979116549
spontaneous zinc deficiency in marmosets, saguinus mystax.moustached marmosets, saguinus mystax, developed alopecia, skin lesions and general debilitation approximately 6 months after being brought into our laboratory. these lesions resembled the signs of zinc deficiency in pigs, rats and squirrel monkeys. the marmosets were fed a commercial monkey diet containing 150 parts per million zinc and about 100 g of apples and oranges per week. the addition of 40 parts per million zinc to the drinking water brought about improvement in hair coat and skin cond ...1979117220
demonstration of human apolipoprotien a in isolated mucosal cells from small intestine and isolated hepatocytes.isolated mucosal cells from the human jejunum and stomach, cryostat sections from the jejunum, isolated parenchymal liver cells and lymphocytes were investigated for the presence of apolipoprotien a (apoa). antisera against purified human apoa-i and apoa-ii were raised in rabbits and conjugated with fluorescein-isothiocyanate (fitc). mucosal cells from jejunum and stomach were isolated with pronase from tissue obtained from operated patients. apoa-i and apoa-ii could be demonstrated in isolated ...1979108182
in vitro response to rosette inhibition factor (rif) and rosette restoring factor (rrf) of human lymphocyte after fractionation on a discontinuous density albumin gradient.in vitro studies on peripheral blood lymphocytes from tuberculous patients and healthy subjects are reported. factors isolated from human serum used in the experiments included the rosette inhibition factor (rif) from serum of tuberculous patients and the rosette restoring factor (rrf) from serum of healthy subjects. lymphocytes were fractionated on a discontinuous bsa gradient. lymphocytes from healthy subjects, sensitive to rif, as well as lymphocytes from tuberculous patients, sensitive to rr ...1979117785
[modelling modification of chemical mutagenesis in human cells. iii. linear index of protection as the standardized criterion of modification].the effect of substances with radioprotective activity, apaetp 2,3 (aminopropylaminoethylthiophosphoric acid 2,3), apaetp 3,3 and cystaphos, on chromosome aberrations, induced by thiotepa in the culture of human lymphocytes was investigated. it is shown that the obtained curves "concentration -- effect" for thiotepa can be described by equations rho = 1 -- e-(kc + alpha)2 and x = e -(kc + alpha)2 --1 for aberrant cells and for chromosome breaks in the presence of the investigated substances. on ...1979118079
a solid-phase radioimmunoassay for bacterial lipopolysaccharide.a radioimmunoassay for e. coli 055:b5 lipopolysaccharide (lps) is described. the lps was derivatised by two new methods and subsequently radiolabeled with 125i to a specific activity of 2-4 mci/mg without apparent loss in its biophysical, immunological or biological activities. using antibody-coated polystyrene tubes, a solid-phase radioimmunoassay was developed with a sensitivity of 10-500 ng/ml of lps.1979108200
macaca assamensis as a new host for experimental plasmodium knowlesi infection. 1978108217
allogeneic restriction of acquired antimicrobial resistance in the rat.allogeneic restriction of acquired antimicrobial resistance was demonstrated by infusing listeria-immune thoracic duct lymphocytes (tdl) into syngeneic, semisyngeneic, or allogeneic recipients that had been infected i.v. with listeria monocytogenes (lm). syngeneic and semisyngeneic recipients enjoyed a high level of protection (3 to 5 log10 reduction in viable organisms within 64 hr, whereas allogeneic recipients were poorly protected (0.5 to 2.5 log10 reduction). sharing one haplotype between t ...197898584
the relationship between the protective and cross-reacting antigens of brucella spp., yersinia enterocolitica 0:9 and salmonella serotypes of kauffmann-white group n.vaccination with killed cells of brucella abortus, yersinia enterocolitica 0:9 and salmonella neusdorf evoked cross-reacting antibodies in guinea pigs but only the homologous antigen effectively produced protective immunity to br. abortus. none of these preparations induced protective immunity to y. enterocolitica in gerbils but all stimulated protective immunity to s. landau in balb/c mice. the antigenic determinants responsible for protective immunity to salmonella infection were located on th ...1979119612
antigen-induced neutrophil chemotactic activity in man. correlation with bronchospasm and inhibition by disodium cromoglycate.we have previously reported increased neutrophil chemotactic activity in sera obtained after positive antigen inhalation responses in atopic subjects. this report describes the kinetics of appearance of this serum activity and the effects of antigen dose and disodium cromoglycate pretreatment on the response in 10 ragweed-sensitive subjects. significantly increased chemotactic activity was present as early as 1 min, peaked at 10 min, and persisted through 24 hr after inhalation of antigen. the i ...197898551
limitations of aeruginocine typing of ps. aeruginosa as an epidemiological marker. 1978108218
["in vitro" activity of a new cephalosporin (cgp-7174-e or cefsulodin) against "pseudomonas aeruginosa" (author's transl)].the minimal inhibitory concentration (mic) of four betalactamins (carbenicillin, ticarcillin, piperacillin and (cgp-7174-e) against 109 clinical isolates of pseudomonas aeruginosa was determined by an agar dilution method. cgp-7174-e was the most active (mic 3.4 micrograms/ml), followed in descending order by piperacillin (mic 4.9 micrograms/ml), ticarcillin (mic 22 micrograms/ml) and carbenicillin (mic 36 microgram/ml). high correlation was found between the mic of these betalactamins (r greate ...1979120122
experimental studies on the serological relationships between yersinia enterocolitica and brucella abortus.yersinia enterocolitica o9 was shown to provoke o, oh and h antibody response in calves. brucella abortus failed to generate yersinia h antibody response and generated brucella o antibodies that cross-reacted with yersinia o and oh antigens. the presence of yersinia h agglutinins along with a higher titre of yersinia oh antibody than brucella o antibody is suggestive of subclinical infection with yersiniosis rather than brucellosis. cross-absorption of sera from calves with established yersinia ...1979120574
annotations on the measurement of liver ferritin, especially in the rat. 1979120687
[oculomotor reflex evoked by vibrassae stimulation in the cat].the oculomotor effects of vibrissae stimulation have been studied in the "encéphale isolé" non-anaesthetized cat. intracellular recording of lateral rectus motoneurones showed an excitatory projection via the ipsilateral infraorbital nerve to these motoneurones. the afferent fibers are type a alpha, recuited with a low threshold (0.2-0.5 ma) and convey information about vibrissae displacement.1979120789
demonstration and characterization of specific binding sites for factor viii/von willebrand factor on human platelets.the presence of specific factor viii/von willebrand factor (fviii/vwf) binding sites on human platelets has been demonstrated by using 125i-fviii/vwf and washed human platelets. binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from 0.2 to 1 mg/ml. binding of 125i-fviii/vwf to platelets can be competitively inhibited by unlabeled human or bovine fviii/vwf, but not by human thrombin, fibrinogen, alpha 2-macroglobulin, equine collagen, or a lectin of ri ...1979108291
unconjugated steroids in the human endometrium. 1975122923
inhibitory effect of normal mammalian sera on the rosette formation of human lymphocytes with sheep red blood cells. 1975123840
non-immunological regression of dimethylbenz(a) anthracene-induced experimental keratoacanthomas in the rabbit.in 9 rabbits, with a total of 17 experimental keratoacanthomas, a search has been made for immune-mediated mechanisms which could possibly be involved in the spontaneous regression of these tumours. immunofluorescence studies did not reveal significant staining patterns. with skin tests, using autologous extracts prepared in three different ways, no delayed cutaneous hypersensitivity reactions were observed.1979104893
[acute enteritis with "new" pathogens. yersinia infections (author's transl)].infections of the intestinal tract with yersinia enterocolitica and yersinia pseudotuberculosis are known the world over. post-infection reactions like arthritis, erythema nodosum, erythema multiforme, scarlatiniform exanthemata and septicemic types deserve particular clinical attention. the clinical importance of enteric yersinioses has been shown in studies with the identification of significant antibody titers against yersinia enterocolitis and yersinia pseudotuberculosis in 6.71 and 4.58% re ...1979105284
mutagenic effect of 7, 12-dimethylbenz[a]anthracene-epidioxide on salmonella typhimurium. 1979106234
[calcium kinetics of myocardium in experimental hypercalcemia and isoproterenol lesions--ultrastructural and roentgen microanalytical findings]. 1978106573
immunochemical studies on a yersinia enterocolitica o:9 lipopolysaccharide cross-reacting with brucella abortus and vibrio cholerae extracts.the presence of two distinct lipopolysaccharides in yersinia enterocolitica o:9 is described: one isolated from the aqueous phase and one from the phenol phase (westphal system). the sugar moiety of the phenol phase lipopolysaccharide has been identified as being responsible for the serologic cross-reaction of y. enterocolitica o:9, brucella abortus and vibrio cholerae. the phenol phase antigen consists of glucose, galactose, glucosamine, 2-keto-3-deoxyoctonic acid, heptose, lipid a and a protei ...1978106756
changes in the activity of lactose synthetase in the goat udder during pregnancy.the lactose synthetase activity of homogenates and particulate fractions prepared from the udders of goats killed at various stages of pregnancy were determined. both components of the enzyme, galactosyltransferase and alpha-lactalbumin, became detectable about half way through the gestation period, at the time when rapid proliferation of mammary epithelial tissue commences. throughout the second half of pregnancy the udder possessed a high level of lactose synthetase activity though the lactose ...1979108321
aging in the rhesus monkey: effects on visual discrimination learning and reversal learning.the behavior of aged rhesus monkeys (18 years and older) was compared to that of young monkeys (3 to 6 years old) to evaluate their relative abilities to learn a series of visual discrimination and discrimination reversal problems. using a subject-paced, automated experimental procedure designed to optimize stimulus control and facilitate execution of choice responses, no consistent age-related differences were observed in the ability to learn new color and pattern discrimination problems of var ...1979108323
[effect of microsporidiosis on the fertility of aedes caspius caspius (culicidae) mosquitoes].effect of microsporidiosis on the fecundity of hosts a. c. caspius was studied. the calculation of eggs in hatches has shown that females developing from infected eggs lay 2--3 times lesser eggs than non-infected ones. besides, the number of females laying eggs decreases considerably. despite the females of mosquitoes suck blood before each egglaying the disease, which proceeds at their larval stage, affects greatly their fecundity. additional feeding of females cannot compensate completely the ...1979108654
[on the antimicrobial activity of propolis and propolis constituents (author's transl)].after a survey of the literature on the antimicrobial activity of the bee product propolis, the authors discuss their own findings as compared to the chemotherapeutical agents streptomycin, oxytetracycline, chloramphenicol, nystatin, griseofulvin and sulphamerazine. according to the results obtained by testing 25 isolated constituents on bacillus subtilis, staphylococcus aureus, candida albicans and trichophyton mentagrophytes, the antimicrobial properties of this mixture of natural substances a ...1979108687
mechanisms of control of the reproductive function by olfactory stimuli in female mammals. 1979108689
sex differences following pharmacological manipulation of the cholinergic system by dfp and pilocarpine. 1979108719
comparison of the discriminative stimulus properties of nefopam and morphine.separate groups of rats were trained to discriminate nefopam or morphine from saline in a two-lever operant task. nefopam produced saline-appropriate responding in morphine-trained rats. the highest dose of morphine tested in nefopam-trained rats produced responding appropriate for neither training treatment. this intermediate morphine responding was antagonized by a naloxone treatment that had no effect on the nefopam discrimination. these results suggest that the stimulus properties of nefopam ...1979108741
observations on l-forms of yersinia enterocolitica. 1979112256
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