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selective culturing of yersinia enterocolitica at a low temperature.stool specimens from patients with suspected yersinia enterocolitica (y. ent.) infection were cultured at +4 degrees c in a nutrient broth for 5 days and at the same time the same stool specimens were cultured by the routine method of the laboratory. the routine method gave 34 y. ent. isolations. selective culturing at +4 degrees c succeeded in isolation of the same 34 y. ent. strains but also 15 further strains or a 44% increase in yield. serial dilutions in broth of 34 strains of y. ent., 7 st ...19751108175
polyarthritis associated with yersinia enterocolitica infection. 19751111133
static pressure-flow relation in the total systemic vascular bed of the dog and its modification by the baroreceptor reflex.to evaluate arterial baroreceptor reflex control of total systemic vascular resistance, we studied the relation between mean arterial blood pressure (p) and mean aortic flow (q) before and after the reflex was abrogated. in 12 dogs with a perfusion pump interposed at the vena-caval-right atrial junction, q was kept at 60, 80, 100, 120, and 140 ml/min kg-1 for up to 20 minutes. there was little time-dependent change in p at any of these flows. when the reflex was intact, the mean p-q curve was on ...19751111997
pathogenecity of yersinia enterocolitica for mice.a laboratory infection of yersinia enterocolitica in mice which closely resembles the naturally acquired human infection is described intravenous inoculation of mice with small numbers of y. enterocolitica gives rise to a systemic, pyogenic infection involving primarily the spleen, liver, and lungs. massive neutrophil infiltration of these organs occurs early in the infection, eventually leading to large abscesses and pulmonary consolidation. mice infected intragastrically show neutophil infiltr ...19751116874
generalized yersinia enterocolitica infection.the clinical course of generalized yersinia enterocolitica infection in 13 patients was observed. two syndromes were apparent; seven patients had an acute septicemic picture, whereas the rest had a subacute localizing infection that usually produced hepatic or splenic abscesses. the latter form often resembled amebic hepatitis clinically, and five of the six patients died despite antibiotic treatment. the acute septicemic form of the disease resembled systemic salmonellosis, and most cases respo ...19751117199
yersinia enterocolitica arthritis.human infections with yersinia were first recognized and reported in upper new york state almost 40 years ago. recently, there have been increasing numbers of reports from scandinavia of episodes of polyarthritis associated with yersinia infections. a 6-month-old girl from upstate new york had a fever of 40 c for two weeks and green watery diarrhea, and irritability was noted when she was handled. an evanescent rash was most apparent at times of temperature elevations. her mother and father had ...19751118210
an electrogenic component of the potential difference in the rabbit lens.the normal resting potential of the rabbit lens, -70mv, is altered to -59mv by ouabain concentrations up to 5-1- minus 6m, and to -52mv at 4 degrees c. ouabain acts only at the anterior lens surface. the temperature effect id completely reversible. the hodgkin-katz-goldman equation can be used with the measured lens potentials and na+ and k+ levels in the lens and bathing medium to obtain alpha, the ration of the membrane permeabilities to na+ and k+. the alpha-values obtained were 0.052 at 4 de ...19751125214
editorial: polyarthritis and yersinia enterocolitica infection. 19751125556
letter: furuncle caused by yersinia enterocolitica. 19751125902
oestrogen hypertension in rats.1. a large dose of oestrogen elevated the blood pressure in male westar rats. 2. plasma renin substrate and renin activity increased significantly but plasma renin concentration was unchanged. 3. the increase in blood pressure induced by oestrogen was significantly reduced by salt loading, plasma renin concentration was suppressed and the increase in plasma renin activity was reduced. 4. the increase in plasma renin activity induced by the increase of plasma renin substrate concentration may pla ...19751126135
determination of (plus or minus)-1, 2-bis(3, 5-dioxopiperazinyl) propane plasma levels in rats, rabbits, and humans by glc and mass fragmentography.specific assay procedures were developed to measure plasma concentrations of (plus or minus)-1, 2-bis(3, 5-dioxopiperazinyl) propane (1) by glc using flame-ionization detection with a sensitivity limit of 5 mug/ml and by glc-mass fragmentography with a sensitivity limit of 0.2 mug/ml. applicability of the assay procedures was demonstrated in rats, rabbits, and humans. plasma concentration-time curves of total 14-c activity and intact i was obtained in rats and rabbits following oral and intraven ...19751133759
[yersinia enterocolitica endemic in tournaisis]. 19751134170
[the clinical significance of yersiniosis. i. results from 3 years of systematic studies on yersinia enterocolitica infections in the copenhagen area]. 19751135958
[the clinical significance of yersiniosis. ii. epidemiological studies on yersinia enterocolitica infections and results of the studies]. 19751135959
case report: fatal yersinia enterocolitica septicaemia.yersinia enterocolitica type 3 was isolated in blood cultures from a previously healthy 81-year-old woman with fever. a high agglutinin titre against this organism was demonstrated in the patient's serum. antibiotic therapy was given according to sensitivity tests but the outcome was fatal due to uraemia.19751145138
case report: septicaemia due to yersinia enterocolitica in a non-compromised host.a case of septicaemia due to yersinia enterocolitica serotype 3, biotype 4, in a non-compromised host is described. the patient showed severe signs of gram-negative septicaemia. treatment with sulphamethoxazole-trimethoprim (bactrim) was unsuccessful in spite of full sensitivity, bactericidal and synergistic effects in vitro. tetracycline gave full restitution.19751145139
on the sugar content of the lipopolysaccharides of the various strains known as yersinia enterocolitica.with a single exception among 11 strains, each strain of y. enterocolitica representing one of the six o-groups possesses, as judged by the sugar composition of its lipopolysaccharides, a particular chemotype. all 14 of the strains examined possessed glucosamine, kdo, two heptoses and glucose. in the most complicated chemotype 10 sugars were demonstrable. of three y. enterocolitica strains not included in the 6 o-groups, two had the same chemotype as the representatives of the o-groups iv and vi ...19751146443
effects of sodium acetylsalicylate on body temperature of monkeys under heat exposure.exposure of taiwan monkeys to 38 degrees c ambient temperature caused: a) raised body temperature, b) restlessness and struggling, c) increased evaporative heat loss and d) increase in tail skin temperature. after the administration of sodium acetylsalicylate, 100 to 250 mg/kg intraperitoneally or 4 to 15 mg intracerebroventricularly (third ventricle) the same heat load caused: a) less increase in body temperature, b) no restlessness or struggling, c) an initially higher rate of evaporative heat ...19751151748
physiological identification of a morphological class of cat retinal ganglion cells.1. small selected patches of retina (approximately 1 mm2) were exhaustively searched electrophysiologically to identify every brisk-transient unit present. the patches were then marked by electrolytic lesions. 2. whole-mount preparations were made from which the distribution of alpha cells within and around the marked areas could be obtained. 3. a one-to-one correspondence could be demonstrated between brisk-transient units and alpha cells. 4. the correspondence was maintained within a patch of ...19751151804
proceedings: effects of histamine, 2-methylhistamine and 4-methylhistamine on blood pressure and vascular resistance in the cat. 19751151865
yersinia enterocolitica in small rodents from norway, sweden and finland.the purpose of the present investigation was to study the occurrence of yersinia enterocolitica (y.e.) among small rodents and shrews (soricidae) from norway, sweden and finland. during a period of one year beginning in the autumn of 1973, animals from seven localities were examined. twenty-four strains of y.e. were isolated from 551 small rodents. isolations were made from six of the seven localities and from six of the nine small rodent species examined. pooled faeces samples from 397 animals ...19751155120
experience with yersinia enterocolitica at the hospital for sick children, 1972-74.thirty-six cases of yersinia enterocolitica infection were detected in the years 1972-74. the form of the illness in young children was acute gastroenteritis and in older children "appendicular syndrome". improved isolation and identification techniques have increased the laboratory recognition of this enteric pathogen.19751156981
proceedings: fine structure of retinal arterioles in experimental hypertensive rats. 19751160166
[terminal ileitis caused by yersinia enterocolitica]. 19751161590
rheumatic fever and yersinia arthritis. criteria and diagnostic problems in a changing disease pattern.a study of rheumatic fever (rf) in finland and sweden was carried out by examining (a) the patients with rf in two hospitals in helsinki, finland during the years 1969-72, (b) the case reports of rf patients in uppsals hospital region (uhr) in sweden during the years 1968-69. in helsinki there were 22 and 2n uhr 16 patients with an acceptably certain diagnosis of rf. of the five "major manifestations" according to jones' revised criteria (circulation, 32: 664, 1965), carditis and polyarthritis w ...19751166282
in vitro depression of cellular immunity by friend virus leukemic spleen cells. 19751168547
impaired hepatic release of triglycerides: a possible cause of acute alcoholic fatty liver in the rhesus monkey.1. the mechanism of development of acute alcoholic fatty liver in the rhesus monkey was investigated by studying the effect of triton wr-1339 on plasma triglycerides. 2. after ethanol infusion, the rise in plasma triglyceride produced by triton was greatly reduced and there was an accumulation of triglyceride in the liver. 3. thus findings suggest that acute alcoholic fatty liver in rhesus monkeys is probably due to a defect in the release of triglyceride from the liver.19751168560
culture of zollinger-ellison tumor cells.we have successfully grown six zollinger-ellison tumors in vitro with use of a monlayer tissue culture technique. the initial gastrin concentration in the medium varied between 0 and 100 ng per ml. many cytoplasmic secretory granules were seen in the cells of one culture population. gastrin secretion was stimulated by the addition of fresh medium to the culture flasks. both the culture cells and the medium were found to contain primarily big gastrin (g-34) but smaller amounts of little gastrin ( ...19751168604
mass occurrence of yersinia enterocolitica in two establishments of collective care of children.mass occurrence of intestinal disorders caused by yersinia enterocolitica simultaneously in two groups of children of under-school age is reported. the question of the source of infection and the routes of transfer are discussed and the various forms pointed out which y. e. infection may take in under-school children within the framework of an epidemic occurrence in a group of children. the fact is emphasized that the results of serological examination using the method of indirect haemagglutinat ...19751168669
[fertility problems caused by infectious agents pigs in the netherlands(author's transl)].the concept of fertility problems is defined in the introduction and their economic importance in pig breeding are pointed out. the infectious causes of the problem are reviewed. infections with l. tarassovi and with aujezky's virus regularly lead to practically endemic abortions; brucella suis and swine-plague infections do so sporadically. the smedi syndrom is considered. the clinical symptoms, diagnosis, epizootiology, and the therapeutical and prophylactic measures of these infections are di ...19751172635
time-dependent changes in commissural field potentials in the dentate gyrus following lesions of the entorhinal cortex in adult rats.previous neuroanatomical work has shown that lesions of the entorhinal cortex in adult rats cause the commissural projections to spread from their normally restricted locus in the inner molecular layer approximately 40-50 mum into the outer molecular layer (that is, into the zone deafferented by the lesion). in the present study we measured the effects of the entorhinal lesion on the distribution of short-latency potentials elicited by commissural stimulation in the molecular layer. studies with ...19751175043
motility-indole-lysine medium for presumptive identification of enteric pathogens of enterobacteriaceae.detection of lysine decarboxylase activity is a useful supplement to reactions on triple sugar-iron (tsi) and urea agars in the initial examination of suspected pathogenic isolates from fecal cultures. owing to the added value of motility and indole production in the differentiation of enteric pathogens, we prepared and evaluated a motility-indole-lysine (mil) medium. the following 890 organisms were tested: 264 shigella, 2 edwardsiella, 182 salmonella enteritidis, 235 s. typhi, 3 arizona, 32 ye ...19751176632
arthritis associated with yersinia enterocolitica infections.74 patients, 42 females, 32 men-all over 10 years of age, with acute arthritis associated with infection with yersinia enterocolitica are presented. the diagnosis was based on serological evidence in all cases (an agglutinin titre of 320 or more), and in 18 of the cases also a positive culture of y. ent. from faeces. the erythrocyte sedimentation rate was very high in most cases. acute enteritis, sometimes with abdominal pain, preceded the acute arthritis with a latent period of about 1-14 days. ...19751179174
[epidemics of yersinia enterocolitica infections]. 19751179383
human serum antibodies against heat-stable antigens from yersinia enterocolitica.human sera, 200 from blood donors and five from patients with infection caused by yersinia enterocolitica serotype 3 (y.e. 3), were tested by indirect haemagglutination for antibodies against antigens from y.e. serotypes 3 and 9. erythrocytes were sensitized using extracts prepared by heating of the bacteria at 100 degrees c for 60 min. all sera tested showed antibody activity against antigen from both y.e. serotypes. in blood donors, the titres ranged from 4 to 512, and in patients from 512 to ...19751180060
[occlusion of the renal artery by intra-arterial injection of thrombin in a case of inoperable renal tumour (author's transl)].in a 53-year-old man with an inoperable metastasizing renal carcinoma embolic occlusion of the renal circulation was achieved by injection of thrombin (600 nih units) through a balloon catheter into the renal artery. with short-term administration of analgesics and under anti-biotic cover the post-embolic course ran without complications. the general condition of the patient is good and macrohaematuria had, at the time of the report, not recurred for two months.19751183357
[similarity of the x-ray picture of enteritis caused by yersinia enterocolitica and regional enteritis]. 19751189249
kinetic measurement of t4 following column chromatography.a kinetic measurement of the eluates from the column purification of t4 is described. the choice of cation exchange chromatography to reduce interfering x-ray contrast substances, and the influence of protein in the reaction have been evaluated. data for precision, inter and intra assay reproducibility, detection limit and normal values are reported. using sample volumes of 0.5 ml and an analysis time of one minute, the proposed method compares favourably with published methods.19751189526
rheumatic fever in adult patients.a study of rheumatic fever in adult patients (diagnosed according to the jones revised criteria; circulation 36: 664, 1965) was performed by examining 26 patients during the acute phase of the disease, and by re-examining 22 of them from 6 months to 64 months later (mean 33 months). polyarthritis and carditis were the most common major manifestations. 23 patients had polyarthritis and 3 monoarthritis. 18 patients had signs of acute cardiac involvement. carditis appeared to be rather benign: at t ...19751190707
comparative in vivo distribution of opiate agonists and antagonists by means of double isotope techniques. 19751196002
brain 2-phenylethylamine as a major mediator for the central actions of amphetamine and methylphenidate. 19751196013
distribution of cholesteryl esters and other lipids in subcellular fractions of the adrenal gland of the pig.total lipids from whole pig adrenal glands as well as from their mitochondria, microsomes, liposomes, and cell sap were extracted and fractionated first into neutral lipids and phospholipids. the highest percentage of neutral lipids was found in the cell sap, and the lowest in the microsomal fraction. neutral lipids were subfractionated into cholesteryl esters, free cholesterol, triglycerides, and free fatty acids. cholesteryl esters were distributed throughout the liposomes. free fatty acids re ...19751196020
pharmacological investigations on elaeocarpus ganitrus. 19751197422
the functional consequences of colectomy.the colon plays a decisive role in salt and water conservation in the intact human, normally removing from the terminal intestine approximately one liter of isotonic fluid that escapes small bowel absorption. the primary purpose of this colon function is probably to prevent extracellular fluid volume depletion and only incidentally to produce a normal solid stool. the patient with an ileostomy can partly adapt to replace the absorptive capacity lost after colectomy but is still vulnerable if sal ...19751200267
ultrastructural studies of the bone marrow in sickle cell anaemia. ii. the morphology of erythropoietic cells and their response to deoxygenation in vitro.electron microscopic studies of bone marrow aspirates obtained from patients with homozygous sickle cell anaemia (hbss) were fixed immediately without attempts to deoxygenate the samples. erythroblasts and normoblasts in these preparations were devoid of haemoglobin polymers or other indications of sickling. furthermore, the nucleated erythroid cells from sickle-cell patients presented an ultrastructural morphology indistinguishable from that of identically-processed erythroid cells in marrow sa ...19751201249
some observations on the possible nutritional significance of vitamin b12-and folate-binding proteins in milk. absorption of [58co]cyanocobalamin by suckling piglets.1. a study was made of absorption of [58co]cyanocobalamin in suckling piglets. cyanocobalamin given at birth and at 7 d of age was efficiently absorbed from the intestine and retained within the body, mostly in the liver. a 10 mug test dose was absorbed no less efficiently than 2-5 mug, despite the virtual absence of intrinsic factor in the gut. in piglets given a 10 mug test dose at different ages between 2-5 and 56 d, there was a marked decrease in the efficiency of retention between about 7 a ...19751201270
animal model of human disease. yersinia enteritis. animal model: oral yersinia enterocolitica infection of mice. 19751211427
[purification of potato virus x]. 19751214646
[experimental pathogenicity of "yersinia enterocolitica" for athymic nude mice (author's transl)].amongst the 4,500 strains of our collection of yersinia enterocolitica usually non-pathogenic for laboratory animals, 5 or 6 strains appeared to be naturally pathogenic for mice. using these strains and non-pathogenic strains representing more than 90 per cent of human isolates in the world (biotype 4, serotype 0:3, phagocyte viii; biotype 2, serotype 0:9, phagotype x3), the pathogenicity for cyclophosphamid treated mice and athymic nude mice has been tested. highly pathogenic strains killed con ...19751217786
erythema nodosum from yersinia enterocolitica. 19751220819
[sensitivity of yersinia enterocolitica to antibiotics].sensitivity of 33 foreign and 10 native strains of y. enterocolitica to tetracycline, aminoglycosides, penicillins, levomycetin and polymyxin was studied. all the strains proved to be resistant to penicillin, oxacillin and ampicillin: they produced penicillinase. the level of resistance to penicillin did not always correlate with penicillin activity. the ability of the native strains to acquire r-factor in vitro from coli bacteria was shown.19751225176
[changes of the inner ear in experimental stapedectomy]. 19751230953
[zoonoses in veterinary practice. 3. chlamydial, rickettsial and fungal infections]. 19751231047
[effusions in the dog. 1. clinico-diagnostic study with special reference to the cytology of the fluid]. 19751231052
wound healing in x-irradiated mammalian skin.certain parameters of wound healing were investigated in mouse skin given 950 rads and 3325 rads of x-irradiation at various times relative to wounding. increased inflammation, delayed dermal regeneration, and delayed contraction were noted in all irradiated groups. the activation of surrounding hair follicles, a process that usually accompanies wounding in mouse skin, occurred earlier, over a shorter elapsed time, and over a greater area of skin in animals irradiated prior to wounding than in t ...19751231061
[progressive polyploidy in mouse liver following repeated hepatectomy].mouse liver regeneration after partial hepatectomy results in sharp changes of ploidy classes towards the increase of high ploidy cells and the decrease low ploidy ones. these changes retain during three months. each following partial hepatectomy (till 3 times) intensifies the hepatocyte polyploidy with appearance of cells with 32--64 ploidy nuclei. the cell polyploidization stimulated by repeated regenerations is similar to that observed in normal postnatal liver growth.19751231096
yersinia enterocolitica as a causative agent of septicaemia.the authors describe the first case of isolation of yersinia enterocolitica from blood in a septic infection in czechoslovakia. they also isolated a strain of y. enterocolitica from an inguinal tumour in the same patient. both strains belonged to biotype 4, serotype 0:3 and phagotype 8 and were non-pathogenic for guinea pigs and hares.19751236885
isolation of yersinia enterocolitica from cow's intestinal contents and beef meat. 19751237057
isolation of yersinia enterocolitica from some animals and meats. 19751237747
[determination of human placental lactogen in the blood of pregnant women by rcc-hpl-ria kit--experimental studies]. 19751240044
[r factor of yersinia enterocolitica. streptomycin (sm) and tetracycline (tc) resistance factor]. 19751240229
[yersinia enterocolitica (author's transl)]. 19751240296
subversion of host defense mechanisms by murine tumors. i. a circulating factor that suppresses macrophage-mediated resistance to infection.the subcutaneous injection of cells of any one of five unselected murine tumors resulted very rapidly in the liberation into the circulation of a small molecular weight factor that severely impaired the capacity of the host to resist experimental infection with listeria monocytogenes and yersinia enterocolitica. it was found that the factor appeared in blood within 8 h of injecting tumor cells subcutaneously. that it possessed potent physiological activity was evidenced by the demonstration that ...19761249520
the lecithin: cholesterol acyltransferase reaction, lysolecithin and red cell ageing in blood stored under normal transfusion service conditions.the lecithin:cholesterol acyltransferase (lcat) activity and lysolecithin content of human blood stored under standard blood transfusion service conditions at 4 degrees c for 6 weeks has been investigated. cooling the blood to 4 degrees c rapidly inactivates the lcat reaction, but the enzyme is not denatured during storage under these conditions. citrate in the anticoagulant did not activate the lcat reaction in freshly-taken whole blood. the total phospholipid and total lysolecithin content of ...19761251568
yersinia enterocolitica in borwn trout (salmo trutta l.) from norway.in this pilot study, 20 brown trout (salmo trutta l.) from one area in western norway were investigated for the presence of yersinia enterocolitica (y.e.). three strains were isolated from three of these trout. all strains were classified as y.e. on the basis of biochemical properties. one of the strains showed antigenic relationship to y.e o-serotype 17. a second strain was antigenically related both to y.e. and y. pseudotuberculosis: agglutination against y.e. o-antisera 4-33, 18, and 21, was ...19761251738
[diseases caused by yersinia enterocolitica in childhood]. 19761253224
temperature-dependent cultural and biochemical characteristics of rhamnose-positive yersinia enterocolitica.clinical isolates of rhamnose-positive yersinia enterocolitica (y.e.rh+) were compared with typical rhamnose-negative y. enterocolitica (y.e.rh-) and with yersinia pseudotuberculosis. the y.e.rh+ differed from the y.e.rh- and y. pseudotuberculosis in their ability to ferment raffinose and lactose, utilize citrate and in their inability to grow on hektoen enteric agar at 22 or 37 c, on salmonella-shigella agar at 37 c, and scant on xylose-lysine-deoxycholate agar at 37 c. an extensive temperature ...19761254709
[yersinia enterocolitica and yersinia pseudotuberculosis in the pathogenesis of abdominal pain in children]. 19761256919
lung abscess and osteomyelitis of rib due to yersinia enterocolitica.the first reported case of infection of the lung and bone with yersinia enterocolitica is described. this organism has only recently been known to infect humans. although a wide spectrum of diseases has been described, all have appeared to be relatively benign; however, in our case a rapid necrotizing process occurred. therefore, the aggressive nature of this organism outside its usual surroundings, eg, the gastrointestinal tract, is worth noting.19761261324
effects of pentadecan-2-one on the growth of cells in culture.the effect of inclusion of trace amounts of pentadecan-2-one in the incubation medium on the growth of hela cells was evaluated by measuring viable cell counts (cells excluding trypan blue) and incorporation of [14c] leucine into acid precipitable protein. evidence is presented to show that exposure of the cells to trace amounts of the methyl ketone, 36mug/ml, effectively inhibits cell growth. this inhibition is relieved by simultaneously incubating the cells with a long chain primary alcohol, h ...19761263759
the anthelmintic treatment of horses. 19761265984
studies on crohn's disease. 1. the relationship between yersinia enterocolitica infection and terminal ileitis.patients with terminal ileitis or regional enterocolitis have been examined for signs of infection due to yersinia enterocolitica serotype 3. the patients were grouped according to the length of preoperative history. among 18 patients with preoperative symptoms of one week or less there were nine with positive signs of yersinia enterocolitica infection. none of these patients developed the chronic form of crohn's disease while two of the primarily yersinia negative patients progressed to the chr ...19761266547
radioimmunoassays for free and conjugated trienbolone and for trienbolone acetate in bovine tissue and plasma samples.a specific, sensitive, precise and accurate radioimmunoassay has been developed for the quantitation of the synthetic anabolic steroid trienbolone acetate (tba) and its major metabolites, free and conjugated trienbolone (tboh) in bovine tissues and plasma. with the extraction procedure described unspecific interference with the antigen-antibody reaction could be ruled out. the assay can significantly detect amounts of more than 40 pg tboh and 70 pg tba. 0.1 - 2.0 g tissue and 0.1 - 1 ml plasma a ...19761273899
a primitive gigantopyramidal field buried in the depth of the cingulate sulcus of the human brain.by stereomicroscopical examination of a complete series of pigment preparations up to 1000 mum thick, a gigantopyramidal area in the brain of man is described, which lies in front of the primary motor field on the medial surface of the hemisphere and is almost totally buried in the depth of the cingulate sulcus extending in both length and width over about 15 mm. serial sections cut in the transverse plane display the field approximately within the limits of the commissura anterior on the one ha ...19761276913
glial cells and extracellular potassium: their relationship in mammalian cortex.simultaneous recordings were made of glial cell potentials and the extracellular potassium concentration ([k+]o) in cat cortex in an attempt to provide more quantitative information about the sensitivity of mammalian neuroglia to changes in [k+]o. a penicillin epileptogenic focus served to generate both transient and sustained elevations in [k+]o, thus allowing measurement of glial membrane potential (vm) at both resting and increased [k+]o levels many times during the same experiment. resting v ...19761276917
absolute configuration of 3-hydroxy fatty acids present in lipopolysaccharides from various bacterial groups.the absolute configuration of 3-hydroxy fatty acids has been studied, which are present in the lipopolysaccharides of the following bacteria: phodopseudomonas gelatinosa, rh. viridis, rhodospirillum tenue, chromobacterium violaceum, pseudomonas aeruginosa, bordetella pertussis, vibrio metchnikovii, vibrio cholerae, salmonella spp., escherichia coli, shigella flexneri, proteus mirabilis, yersinia enterocolitica and fusobacterium nucleatum. the 3-hydroxy acids were liberated by strong alkaline hyd ...19761278168
[the affinity lavage of the abdominal cavity in diffuse peritonitis with liquid sorbents based on cross-linked dextrans].experiments were conducted on 35 wistar rats with generalized purulent peritonitis. twenty-four hours after infection the authors introduced into the animals' abdominal cavity gels of cross-linked dextrans with immobilized polymixin (50 mg/g dry weight) and terrilithin (100 pe/g dry weight), as well as a combination of these sorbents with 24-hour exposure in a 5 ml volume. the object of the study was the detoxification effect. the authors revealed a phenomenon of agglutination of red cells of an ...19921280308
epitope homology between bacterial heat shock protein and self-proteins in the host cell.mouse monoclonal antibodies (mabs) showing distinct reactivity against the 60-kilodalton (kda) antigen heat shock protein of yersinia enterocolitica, designated cross-reacting protein antigen (crpa), have previously been established. the reactivities of these mabs (5c3 and 3c8) against mouse and human host cells were studied by western blotting and flow cytometric analysis. the results indicated that epitopes on the bacterial 60-kda heat shock protein are present on various molecules in mouse sp ...19921282022
bacteriocin-like antagonism in yersinia enterocolitica.a total of 121 yersinia enterocolitica o3 isolates from patients with gastroenteritis and 37 y. enterocolitica reference strains with different o antigens were tested for bacteriocine production and sensitivity. by using cross-streaking method strains belonging to serogroups of o5; o7,8; o7,13; o11; o11,23; o13,27; o17; o19,8 and o34 produced bacteriocin-like substances. none of the y. enterocolitica o3 strains produced bacteriocin-like material and most of them were uniformly sensitive against ...19921284897
in vivo neutralization of tumor necrosis factor-alpha and interferon-gamma abrogates resistance to yersinia enterocolitica infection in mice.cytokines are important mediators of the inflammatory host response against infectious agents. in this study, the role of tumor necrosis factor-alpha (tnf-alpha) and interferon-gamma (ifn-gamma) in the elimination of a primary infection with highly virulent yersinia enterocolitica serotype 0:8 strain wa-p has been investigated in c57bl/6 mice. the injection of anti-tnf-alpha or anti-ifn-gamma antibodies ("serotherapy") prior to the intravenous challenge of a sublethal dose of y. enterocolitica c ...19921287419
[biological characteristics of tumor growth delay in human nasopharyngeal carcinoma xenograft (npc-837) after irradiation].tumor growth and cell cycle of human nasopharyngeal carcinoma xenograft in nude mice (npc-837) after irradiation were studied. after cobalt-60 irradiation of 5.0gy, 7.5gy, 10gy, 15gy and 20gy, the tumor volume was reduced to 80, 70, 50, 35 and 10 percent of the control, respectively. however, the tumors began to grow again. the time (in days) the tumors took to reach the volume of the control was radiation dose-dependent. with 20 gy irradiation the tumor volume was kept at 10% of the control lev ...19921291288
influence of a 70 kilobase virulence plasmid on the ability of yersinia enterocolitica to survive phagocytosis in vitro.during the course of infection, yersinia enterocolitica invades tissues where macrophages and polymorphonuclear leucocytes (pmns) constitute the first line of defence. as expression of virulence in y. enterocolitica is governed in part by a c. 70 kilobase virulence plasmid (pyv), we investigated the influence of this plasmid on the interaction between y. enterocolitica and phagocytes in vitro. the results showed that, irrespective of plasmid-carriage, yersiniae survived phagocytosis by macrophag ...19921291840
[a case of intestinal septicopyemia caused by yersinia enterocolitica in a 13-year-old girl]. 19921291965
mechanism of action of tricyclic drugs on escherichia coli and yersinia enterocolitica plasmid maintenance and replication.tricyclic medical compounds like many other non-antibiotics exhibit antimicrobial activities. two chemically representative groups were tested in plasmid dna transformation and replication to assign intracellular target sites responsible for the multiple effects in escherichia coli and yersinia enterocolitica cells. to analyse the mechanism of action at the molecular level, the effects of chlorpromazine, 7,8 dioxochlorpromazine, promethazine, methylene blue, imipramine, cannabidiolic acid and te ...19921295474
transfusing yersinia enterocolitica. 19921298257
inactivation of yersinia enterocolitica by nitrite and nitrate in food.the antimicrobial effects of sodium nitrite and sodium and potassium nitrate against yersinia enterocolitica were investigated in solution and in treated pork meat. potassium nitrate and sodium nitrate showed only feeble antimicrobial activity in cultures; no antimicrobial activity was detected with sodium nitrite. conversely, all three salts displayed apparent antimicrobial activity in pork meat, possibly due to selective effects on competitive flora.19921298643
[studies of the lymphatic system in mice infected with trichinella pseudospiralis as well as infected and stimulated by phytohaemagglutin (pha-p)].mice cfw were infected per os with trichinella pseudospiralis (150 larvae/mice). the mice were divided in two groups: nonstimulated and stimulated intraperitoneally with pha-p at dose 10 mg/kg body weight. the animals were killed 7, 14, 21, 28, 42, 56, 70 and 150 day post infection (d.p.i.). spleen et mesenteric lymph nodes were examined histopathologically (hematoxylin-eosin) and histochemically (nonspecific esterase reaction) for differentiation of t lymphocytes. the obtained results reveal th ...19921299055
frequency of isolation of yersinia enterocolitica from livestock in trinidad. 19921300681
biotypes and sensitivity screening yersinia enterocolitica as an infective agent in man and swine in nigeria.diarrhoeic faecal samples from 210 humans and 192 swine were screened for yersinia enterocolitica in 1990. ten and 8 y. enterocolitica strains were isolated from pig and man, respectively. the isolates were found to belong to wauter's biotypes 1, 2, 3 and 4. biotype 2 was isolated mainly from human stool samples. biotype 3 was found only in swine while biotypes 1 and 4 were isolated from both man and swine. all the 18 strains showed varying degrees of sensitivity to antibiotics used in this inve ...19921301624
serological diagnosis in human yersinia infections.serological examinations revealed y. enterocolitica 0:3 specific antibodies in 34% of 80 children affected by a yersiniosis epidemic at titres of 1/40-1/640 and in all sporadic yersinia enteritis cases. similarly, agglutinins were identified for y. enterocolitica 0:3 and 0:9 in 3.4% of 430 appendectomized children hospitalized with painful syndrome in the right iliac fossa. in 10% of 101 patients hospitalized with arthritis and reiter's syndrome antibodies to y. enterocolitica 0:3 (8 cases) and ...19921304827
cytochrome p450-dependent metabolism of dextromethorphan: fetal and adult studies.dextromethorphan undergoes o-demethylation to dextrorphan and n-demethylation to 3-methoxymorphinan. 3-hydroxymorphinan, a didemethylated compound, is secondarily formed. the o-demethylation pathway to dextrorphan is polymorphic and under cyp2d6 genetic control. adult and fetal studies were performed to characterize the cytochrome p450 families involved in dextromethorphan metabolism and their ontogeny. in adult volunteers in vivo and in vitro studies demonstrate that the o-demethylation pathway ...19921306804
[the dynamic indices of human thermal status during overheating exposures].the thermal state of 7 naked test subjects on a 25 min of work (325 j/s) at 40 degrees c and 85% humidity of the ambient air has exceeded the acceptable limits. the thermal protecting garment having high thermal resistance indices was tested near a fire source. the subjects performed the 254 j/s and 403 j/s work so long as they were able to do it. time of work was, on average, 17 and 12 min, respectively. by the end of work, thermal state of the subjects approached to a "limiting" value: heart r ...19921307041
[occurrence of bacteria of the yersinia genus in surface water].the aim of the study was determination of the frequency of occurrence of yersinia genus bacteria in surface waters polluted to various degrees with bacteria of the coliform and of fecal coli. for detection of yersinia rods the previously elaborated medium endo mlce and the membrane filter method were applied. samples of 42 surface waters were examined, including 26 from rivers and 16 from lakes, ponds and clay-pits. on the basis of sanitary bacteriological analysis 16 surface waters were classif ...19921308748
[1st isolation of yersinia enterocolitica in algeria].yersinia enterocolitica has been researched in 200 samples of human stools, 40 animals excrements, 38 specimens of soils and 46 of water; the microorganism has been recovered in respectively 3.5%, 10%, 10.5% and 26% out of the total of samples examined; the strains isolated belong to different wauter's biotype scheme but the biotype 1 is the most predominant except in soil samples. none of biotype 2 and 4, admitted to be adapted to man, has been isolated from human stools. we think that the noti ...19921309136
[various isolation and enrichment media for isolating yersinia enterocolitica].study of different isolation and enrichment media for recovering yersinia enterocolitica has been carried out. the best data have been obtained after enrichment in phosphate buffer with sorbitol and bile salts, followed by a decontamination with aulisio's koh and streaking into hectoen medium.19921309142
lipopolysaccharide o side chain of yersinia enterocolitica o:3 is an essential virulence factor in an orally infected murine model.the rfb gene cluster of yersinia enterocolitica o:3, responsible for the biosynthesis of the o side chain, was previously cloned, and a y. enterocolitica o:3 side chain-specific bacteriophage (phi yeo3-12) was isolated (a. al-hendy, p. toivanen, and m. skurnik, microb. pathog. 10:47-59, 1991). this paper describes the isolation and characterization of the bacteriophage phi yeo3-12-resistant mutant of y. enterocolitica o:3, yeo3-r2. lipopolysaccharide isolated from yeo3-r2 lacked the o side chain ...19921311707
epidemiology of yersinia pseudotuberculosis and y. enterocolitica infections in sheep in australia.infections with yersinia pseudotuberculosis serotype iii and y. enterocolitica serotype o2,3 were found to be common in australian sheep flocks. transmission of y. pseudotuberculosis occurred in late winter and early spring, while y. enterocolitica transmission occurred from midwinter to early summer. excretion of y. pseudotuberculosis was limited to the winter and spring period and was particularly common in 1- and 2-year-old sheep. infection persisted for up to 14 weeks. y. pseudotuberculosis ...19921313049
igg and iga antibody responses against porins in yersinia-triggered reactive arthritis.using an enzyme immunoassay, the development and persistence of serum igg and iga class antibody responses against porins, a class of the major outer membrane proteins, were compared between patients who developed reactive arthritis and subjects who did not after yersinia infection. a significant difference was seen between the two patient groups in the beginning of the disease: those with reactive arthritis had higher levels of igg and iga class antibodies against the porins. a similar differen ...19921316199
transition from interleukin 1 beta (il-1 beta) to il-1 alpha production during maturation of inflammatory macrophages in vivo.in situ production of interleukin 1 alpha (il-1 alpha) and il-1 beta was investigated in peyer's patches (pp) of mice undergoing an acute bacterial infection with yersinia enterocolitica o8. synthesis of il-1 beta, as determined by immunohistochemistry, was found primarily in monocytes migrating into the inflamed pp. in comparison, synthesis of il-1 alpha was temporarily delayed by at least 24 h and was only found in mature macrophages, which did not produce detectable levels of il-1 beta. this ...19921316934
free radical metabolism of halothane in vivo: radical adducts detected in bile.two radical adduct species have been detected in the bile of living rats treated with halothane and phenyl-n-t-butylnitrone (pbn). the treatment of rats with 12% oxygen was required for radical adduct detection. analysis of the corresponding epr spectra obtained when deuterated pbn and deuterated halothane or [2-13c]halothane was used shows that these two species result from the spin trapping of two halothane-derived free radicals. coupling constants were an = 15.72 g, a beta h = 2.09 g, a gamma ...19921317002
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