Publications

TitleAbstractYear
Filter
PMID
Filter
studies of the histochemistry, ultrastructure, motor innervation, and regeneration of mammalian intrafusal muscle fibres. 1976137430
[diuretic action of calcitonin: demonstration of an inhibiting effect on sodium reabsorption in the ascending limb of henlé's loop].it was found that calcitonin (porcine) at the dose: 4 i.u. mrc./kg/hr (i.v.), in the rabbit, increased the diuresis and oxmolal excretion, and simultaneously decreased free-water reabsorption and urinary osmolality. the results suggest that calcitonin acts by inhibiting sodium reabsorption in the ascending limb of henl's loop. this hypothesis was confirmed by renal autoradiography study with 22na.1976140734
[therapeutic results in an epidemic outbreak of dysentery].the therapeutical results obtained in an epidemical outbreak of dysentery caused by shigella flexneri type 2 a are reported, emphasizing the bacteriological failure of the treatment with furazolidin in 52.1% of the cases and the good results obtained with neomycin (mycerine).1977141082
a reconstituted na+ + k+ pump in liposomes containing purified (na+ + k+)-atpase from kidney medulla.liposomes containing either purified or microsomal (na+,k+)-atpase preparations from lamb kidney medulla catalyzed atp-dependent transport of na+ and k+ with a ratio of approximately 3na+ to 2k+, which was inhibited by ouabain. similar results were obtained with liposomes containing a partially purified (na+,k+)-atpase from cardiac muscle. this contrasts with an earlier report by goldin and tong (j. biol. chem. 249, 5907-5915, 1974), in which liposomes containing purified dog kidney (na+,k+)-atp ...1977141941
ligand-dependent tryptic inactivation of the ouabain sensitivity of adp-atp exchange catalyzed by canine renal na+, k+-atpase. 1977143280
[a case of bacteremia caused by shigella flexneri]. 1977143707
cardiac hypertrophy and antihypertensive therapy.biochemical (myocardial dna, rna, and hydroxyproline) and humoral (plasma [pra] and kidney [kra] renin activity) factors were determined in spontaneously hypertensive rats (shr) and normotensive wistar controls (nr) before and following treatment with minoxidil or propranolol. minoxidil (150 mg.litre-1 drinking water) effectively controlled blood pressure (17.3 kpa vs 24.9 kpa [130 mmhg vs 187 mmhg], p less than 0.001) despite marked and sustained increases in both pra and kra ventricular weight ...1977145319
[role of dysentery transmission factors in relation to the degree of environmental pollution]. 1978146641
[effectiveness of an agent of 8-hydroxyquinoline group in treatment of acute dysentery]. 1978148164
a fair deal for the handicapped. 1978148882
the cardiomyopathy of the syrian hamster (strain bio 8262)--hypertrophic or dystrophic?chemical as well as cytophotometric studies were carried out on myocardium of cardiomyopathic hamsters of strain bio 8262 and of healthy control hamsters of strain clac. our interest was to find out whether the cardiomyopathic hamsters suffer from hypertrophic cardiomyopathy or not. the heart muscle mass was only slightly increased in the older cardiomyopathic hamsters when compared with the controls. this increase was accompanied by an elevated content of total dns, rns and protein. furthermore ...1978148886
changes in immunological activity of rat lymphoid organs during pregnancy.immune reactivity in lymhoid organs of rats during the last week of syngeneic (lewis: l x l) or allogeneic (females lewis x males wistar: l x w) pregnancy was compared with that found in non-pregnant animals. the thymus weight was slightly reduced and the response of thymic lymphocytes to phytohaemagglutinin and concanavalin a was slightly, but not significantly, elevated in pregnant rats. by contrast, the response of lymphoid cells from spleen and mesenteric lymph nodes to the mitogens was redu ...1978149623
effect of human immunoglobulin preparations on fc rosette formation between anti-d-coated erythrocytes and lymphocytes.human immunoglobulin (ig) preparations were tested for their inhibitory effect on fc rosette formation between anti-d-coated human erythrocytes and lymphocytes, as compared to their complement activating capacity. both of the two biological activities ascribed to the sites in the fc portion of the igg molecules were found to be reduced in the pepsin-treated, as well as in the s-sulfonated ig preparations, as compared to the activities of the normal human ig preparation. in the plasmin-treated ig ...1978150144
[role of a water factor in seasonal fluctuations of the incidence of acute intestinal infections]. 1978151464
enhanced glycogen turnover in skeletal muscle of uremic rats--cause of uncontrolled actomyosin atpase? 1978152057
[the triangular ligaments of the dog]. 1978152067
effects of 5,6-dihydroxytryptamine and 5,7-dihydroxytryptamine on the rat central nervous system after intraventricular or intracerebral application and on blood platelets in vitro. 1978152083
irs, hew threaten triple-a bonds. 1978152403
[biochemistry of myocardium taken at autopsy. preliminary report].the findings after biochemical analysis of heart muscle taken at autopsy are given in this preliminary communication. human myosin is made up of two heavy sub-units and two light sub-units: it is similar to cardiac myosin found in other mammals, but is different in certain characteristics, particularly immunological ones. tropomyosin is made up of two different sub-units. the normal human heart contains 1 mg of collagen and 130 microgram of desoxyribonucleic acid (dna) per 100 mg of fresh tissue ...1978152617
inhibition of four human serine proteases by substituted benzamidines.a series of substituted benzamidines has been examined for their inhibitory activity against the human serine proteases--trypsin, thrombin, plasmin, and c1s, a subunit of the first component of complement. the inhibition constants obtained for each enzyme were correlated with physical-chemical properties of the substituent group using the quantitative structure-activity relationship approach. this analysis indicated that plasmin and c1s are very similar in their interactions with substituted ben ...1978152812
[receptor adaptation of muscle spindles treated in different ways].comparison of the grades of 60 sensitive muscle spindle terminals on two actions: gradual stretch of the muscle and short intensive tetanization of the muscle nerve, showed that, irrespective of the mode of action, the character of adaptation remains the smae in majority of units. the speed of receptors adaptation depends not on the specific of testing precedures, but, apparently, on the means of connection of the sensitive terminals with different types of intrafusal muscle fibers with differen ...1978153244
[correlations of the level of plasmin system and blood serum hyaluronidase activity with pathology of the large intestine in dysentery]. 1979156400
circular dichroism and ultraviolet absorbance of calf thymus dna in presence of ch3hgoh. 1979156470
patterns of neuromuscular disease. as related to stages of normal embryogenesis in voluntary muscle.skeletal muscle samples from the upper and lower extremities of 38 human fetuses (6 to 18 weeks' gestation) of both sexes were studied by histologic, histochemical, and electron microscopic methods. ultrastructural morphometry was applied. in the different stages of normal development are found regressive changes, ranging from reversible dystrophic to irreversible necrotic alterations, which are characteristic of either primary myogenic myopathies or primary neurogenic muscle atrophies in older ...1979156504
the influence of the gamma system on cross-correlated activity of ia muscle spindles and its relation to information transmission.in the decerebrate cat during static or slowly varying (less than 0.3 hz) muscle stretches, the activity of muscle spindle (ms) pairs was poorly correlated and such correlation was not changed after ventral root sectioning. with slightly faster sinusoidal stretches (0.3-20 hz) activity in pairs of ms was also poorly correlated. however, sectioning of the ventral roots produced preferential firing frequencies in the same muscle spindle pairs and increased their degree of correlation. the increase ...1979156885
[activity of the plasmin enzymatic system and of serum hyaluronidase in dysentery]. 1979159382
studies on human sexual development. vi. concentrations of unconjugated dehydroepiandrosterone, estradiol, and estriol in amniotic fluid throughout gestation.concentrations of unconjugated dehydroepiandrosterone, estradiol, and estriol were measured in samples of amniotic fluid from uneventful pregnancies of 9-40 weeks conceptual age. there was no apparent influence of fetal sex upon the levels of these steroids. dehydroepiandrosterone concentrations rose slightly from 9-20 weeks, and then showed little further change. estradiol concentrations declined slightly from 9-20 weeks; after 32 weeks gestation, there was a 2-fold rise to term. estriol levels ...1978162521
inactivation of viruses and bacteria by ozone, with and without sonication.selected organisms with public health significance were placed in a reaction chamber for treatment by ozonation, by ozonation and sonication, by sonication, or by sonication during oxygenation. vesicular stomatitis virus, encephalomyocarditis virus, gdvii virus, staphylococcus aureus, pseudomonas fluorescens, salmonella typhimurium, enteropathogenic escherichia coli, vibrio cholerae, and shigella flexneri were inactivated by treatment with ozone. when microorganisms were suspended in phosphate-b ...1975163616
muscle spindles in the human anterior digastric muscle.the occurrence of muscle spindles in the anterior digastric muscle in man was investigated and the fibre calibre spectrum of the corresponding nerve was determined. after removal at autopsy from five individuals of both sexes (aged 23--73), the muscles were stained with weigert's iron hematoxylin-van gieson stain and the nerves according to the alzheimer - mann - häggqvist method. altogether 12 spindles were found in five out of ten muscles. only muscles from one individual were devoid of spindl ...1979162026
oncogenic transformation of murine lymphoid cells by in vitro infection with abelson leukemia virus.spleen cell cultures stimulated to dna synthesis by antigen or mitogen were infected with abelson virus, a c-type rna virus inducing nonthymic lymphomas in mice. after 3 days the cells were transferred to mice and caused 100 percent incidence of lymphomas in as few as 29 days. that a number of the tumors were of donor origin, as shown by female karyotypes in recipient male mice, indicated that cells infected by virus in vitro were transformed. the process depended upon both virus and stimulation ...1975165315
pathophysiology of acupuncture: nervous system transmission.as far as we know, this is the first scientific report which shows distinctly that acupuncture is transmitted directly by the nervous system and the performance of analgesic acupuncture requires an intact nervous system. the more distal the acupuncture treatment is given upon the nerve, the greater the degree of analgesia is afforded. the slowing from a normal awake beta to a normal awake alpha electroencephalographic rhythm may have some effect on the patient's pain perception but further inves ...1975164810
prevention of gram-negative bacillary pneumonia using polymyxin aerosol as prophylaxis. ii. effect on the incidence of pneumonia in seriously ill patients.all 744 patients admitted to a respiratory-surgical intensive care unit (rsicu) were included in a prospective study of the effects of a polymyxin (2.5 mg/kg body wt/day in six divided doses) or a placebo aerosol sprayed into the posterior pharynx and tracheal tube (if present), during 11 alternating 2-mo treatment cycles. the incidence of upper airway colonization in the rsicu with pseudomonas aeruginosa was 1.6% during the polymyxin treatment cycles (total 374 patients) and 9.7% during the pla ...1975163848
detection of memory cells by chemical modification of the lymphocyte cell surface.stringent alloantigen requirements, necessary for the differentiation of human memory cells into specific secondary cytolytic t cells (2 degrees ctl), can be bypassed by chemical modification of memory cells with the mitogenic oxidising agent, galactose oxidase. treatment of memory cells generated in a long-term primary mixed lymphocyte culture with neuraminidase and galactose oxidase (nago) results in the differentiation of memory cells into 2 degrees ctl. in contrast, treatment of unprimed cel ...1979162003
[classical and current aspects of the formation of motor dominance in man].in the paper, significance of driving phenomenon for formation of motor dominant is considered and experimentally corroborated with the aid of autocorrelation and spectral analysis of the working man's eeg. the a.a. ukhtomsky classical postulate has been complemented by contemporary ideas of the role of phasic relationships between the cortical activity for extablishing intercentral interconnections and the functional differentiation of working and irrelevant cortical structures. data of corre ...1975165986
thymosin-induced differentiation of murine thymocytes in allogeneic mixed lymphocyte cultures.calf thymosin is shown to enhance the one-way mlr of cba thymocytes cultured with allogeneic mitomycin-c- treated c57bl/j6 spleen cells. thymosin does not enhance the one-way mlr of cba thymocytes cultured with syngeneic mitomucin-c-treated spleen cells. based on this finding we present a relatively simple, rapid and quantitative in vitro microculture hioassay for inducers of t-cell differentiation and propose that thymosin treatment, when accompanied by antigen presentation, induces the two-ste ...1975165764
turnover of plasma total and very low density lipoprotein triglyceride in man.basal plasma total triglyceride and very low density lipoprotein (vldl) triglyceride turnover rates were determined in 110 subjects whose triglyceride concentrations ranged from low normal to markedly elevated values. the mean total triglyceride turnover rate was 13.7 mg - kg-1- hr-1, whereas the mean vldl triglyceride turnover rate was 13.2 mg - kg-1 - hr-1. a highly significant correlation was present between the two turnover rates (r equal + 0.75). the endogenous serum triglyceride transporte ...1975167428
regulation of sensitivity to beta-adrenergic stimulation in induction of pineal n-acetyltransferase.stimulation by isoproterenol causes large increases in the activity of rat pineal n-acetyltransferase (arylamine acetyltransferase or acetyl-coa:arylamine n-acetyltransferase, ec 2.3.1.5) after a variable lag period. lengthening periods of exposure to light cause rapid increases in the sensitivity of pineal n-acetyltransferase to induction by isoproterenol. this supersensitivity, which develops gradually over a 12 hr period, is correlated with increasingly longer lag periods in the induction of ...1975168570
a method fof production or antisera to hepatitis b antigen subtypes, and the distribution of subtypes d and y among norwegian hepatitis b patients.a method for production of antisera to hepatitis b antigen (hbsag) subtypes d and y is described. the method is based on the coupling of hbsag to a colloidal silica gel (aerosil), and the selective adsorption of unwanted antibodies from antisera with this preparation. some results obtained with norwegian hepatitis patient sera are included.1975168728
revertants of escherichia coli mutants defective in the cyclic amp system. 1975165780
functional consequences of modifying highly reactive arginyl residues of fructose 1,6-bisphosphatase. loss of monovalent cation activation.modification of pig kidney fructose 1,6-bisphosphatase with 2,3-butanedione (in the presence of amp) results in the loss of activation of the enzyme by monovalent cations. under these conditions about 8 arginyl residues per mole of enzyme were modified. no other residues were modified. no loss of monovalent cation activation occurs when modification with 2,3-butanedione is carried out in the presence of amp plus the substrate fructose 1,6-bisphosphate and 3.2 less arginyl residues were modified. ...1975169892
cell-mediated cytotoxicity to chemically-induced rat tumours.cell-mediated immune reactions against carcinogen-induced rat tumours were demonstrated by the in vitro microcytotoxicity test. lymph-node cells from syngeneic rats immunized against individual aminoazo-dye-induced hepatomas or 3-methylcholanthrene-induced sarcomas were cytotoxic for cells of the immunizing tumour compared with the effects of normal lymph-node cells. only a low level of cross-reactivity was detectable against target cells derived from otherr tumours. conversely, lymph-node cells ...1975170224
angel rotor countercurrent chromatography. 1975165750
antibody levels to parainfluenza, rubella, measles, and influenza a virus in children with polymyositis.the cf and hi antibody titers to rubella and measles viruses, the cf titers to influenxa a, and the hi titers to parainfluenza 1, 2, and 3 were carried out on the sera of 20 patients with childhood polymyositis and their matched controls. the titers for measles, parainfluenxa 1, and influenza a were slightly higher for patients than for controls. the control group had antibody titers to rubella and parainfluenza 2 and 3 higher than or similar to those of patients. strong patterns or significant ...1975168906
[characteristics and types of clostridium perfringens derived from various animals]. 1975170433
[a cell-line with 27 chromosomes in a human acute leukemia (author's transl)].chromosomal analysis of the bone-marrow aspirate of a five years old girl suffering acute leukemia revealed a cell-line carrying 27 chromosomes. banding by controlled heating denaturation showed that, in these cells, all chromosomes are haploid, except chromosomes: x, 10, 18, 21. this cell-line, not seen during remission, was found during relapse, in addition to another one with 54 chromosomes. the caryotype of this last clone corresponded to the duplication of the chromosome set found in the fi ...1975170589
effect of cellular desialylation on choline high affinity uptake and ecto-acetylcholinesterase activity of cholinergic neuroblasts. 1975172090
effects of indomethacin on intestinal secretion, prostaglandin e and cyclic amp: evidence against a role for prostaglandins in cholera toxin-induced secretion.the effects of indomethacin on intestine mucosal camp, intestinal fluid secretion, and mucosal and fluid pge were studied in rabbits in vivo following challenge with cholera toxin. indomethacin had no effect on cholera toxin-induced fluid secretion or camp accumulation. inhibition of pge synthesis was achieved by the administration of two but not one injection of indomethacin. these studies provide evidence against a role for pge in mediating cholera toxin-induced secretion and point out the nee ...1975172982
ultrastructural myocardial changes produced by viruses.some of the ultrastructural pathological alterations in the myocardium produced by viral infections with members of the picornavirus group are described. these alterations varied from mild to severe, with necrosis. in animals infected with coxsackie b1 virus and emc virus, readily identifiable viral crystals were frequently found in association with the myocardial lesions by means of electron microscopy. the electron microscope made it possible to study vary early myocardial changes which were n ...1975172990
discussion: nigrostriatal projections and the "dopamine report". 1975173061
sexual differentiation in aspergillus nidulans: the requirement for manganese and the correlation between phosphoglucomutase and the synthesis of reserve material.aspergillus nidulans was completely devoid of fruit bodies when grown on manganese deficient cultures. this result was shown earlier to be due to a lack of alpha-1,3 glucan in the cell wall. several enzymes of carbon and nitrogen metabolism were investigated in an attempt to explain the absence of this reserve material. synthesis of glucose-6-phosphate dehydrogenase, phosphoglucoisomerase and aldolase, were not strongly affected by manganese deficiency. however, phosphoglucomutase showed only 60 ...1975173248
glomerular deposition of immune complexes in dogs following natural infection with canine adenovirus.the renal lesions were studied in eight dogs which had either died as a result of acute canine adenovirus infection (rubarth's disease) or were in various stages of recovery from the clinical disease. using immunofluorescence techniques granular deposits of igg were detected in the glomeruli of six dogs; four of these animals had similar glomerular deposits of canine adenovirus antigen. eluates obtained from kidney tissue of four dogs were found to contain antiviral antibody. histologically thos ...1975166480
catabolite repression of pseudomonas aeruginosa amidase: isolation of promotor mutants.among mutants of pseudomonas aeruginosa isolated from fluoroacetamide medium were some which synthesized amidase at about 5% of the rate of the parent constitutive strain, pac101. seven fluoroacetamide-resistant mutants with low amidase activity gave rise to secondary mutant strains on succinate+butyramide plates. one appeared to be an 'up-promotor' mutant and synthesized amidase at a high rate. this mutant, pac433, was not stimulated by cyclic-amp and was much less sensitive to catabolite repre ...1975170366
mapping rnase t1-resistant oligonucleotides of avian tumor virus rnas: sarcoma-specific oligonucleotides are near the poly(a) end and oligonucleotides common to sarcoma and transformation-defective viruses are at the poly(a) end.the large rnase t1-resistant oligonucleotides of the nondefective (nd) rous sarcoma virus (rsv): prague rsv of subgroup b (pr-b), pr-c and b77 of subgroup c; of their transformation-defective (td0 deletion mutants: td pr-b, td pr-c, and td b77; and of replication-defective (rd) rsv(-) were completely or partially mapped on the 30 to 40s viral rnas. the location of a given oligonucleotide relative to the poly(a) terminus of the viral rnas was directly deduced from the smallest size of the poly(a) ...1975170411
proceedings: phosphatidylinositol kinase activity in rat parotid secretory granules. 1975173677
unique virus-related dna sequences in sheep progressive pneumonia lung.hybridization studies with [3h]-cdna of progressive pneumonia, maedi and visna viruses demonstrate that lung dna from sheep afflicted with progressive interstitial pneumonia possesses virus-related sequences not present in normal sheep lung dna.1975173794
noradrenergic subsensitivity and supersensitivity of the cerebral cortex after reserpine treatment.changes in the sensitivity of the cyclic adenosine 3', 5'-monophosphate response of rat brain cerebral cortical slices to norepinephrine were measured in vitro after the rats received i.p. injections of reserpine (1 mg/kg). subsensitivity was evident 1 hour after a single reserpine treatment compared with saline controls. however, if reserpine was injected daily for 4 days followed by 1 day without reserpine treatment, a supersensitive response to ne was shown compared to the controls. mean pd2 ...1976173828
a ribosome-dependent gtpase from yeast distinct from elongation factor 2.three proteins required for poly(u)-directed polyphenylalanine synthesis have been separated from yeast. two of the factors correspond to the elongation factors 1 and 2 described for other eukaryotic systems, according to the criteria of phenylalanyl-trna binding and diphtheria toxin-catalyzed adp-ribosylation. the third protein, while absolutely required for polyphenylalanine synthesis, was a more active ribosome-dependent gtpase than elongation factor 2.1976174100
phosphoprotein phosphatase activity in the thyroid.phosphoprotein phosphatase activity in the calf thyroid was found in various subcellular fractions. the relative amount in each fraction varied according to the substrate used: the 500g fraction had the highest specific activity when protamine was used, while the 5000g fraction was highest when histone was used. triton x-100 tended to increase activity in all the particulate fractions, the greatest change being found in the 105,000g pellet. deae chromatography of the 105,000 g supernatant resolv ...1975174136
substrate specificity of lecithin:cholesterol acyltransferase. esterification of desmosterol, b-sitosterol, and cholecalciferol in human plasma.desmosterol and beta-sitosterol were esterified when incubated with normal human plasma. the initial rate of demosterol esterification was 1.7 times faster, and that of beta-sitosterol 0.4 times slower, than the esterification rate of cholesterol. these ratios were found to be almost the same when plasma from different normal individuals was tested. plasma from a patient with familial lecithin:cholesterol acyltransferase deficiency did not esterify any of the sterols. the esterification of desmo ...1975174187
structural studies on d-specific polysaccharide of shigella flexneri serotype 6. 1976173550
biosynthesis and secretion of testosterone by adrenal tissue from the north american opossum, didelphis virginiana, and the effects of tropic hormone stimulation. 1975173619
heterotropic interactions of ligands with phosphorylase b.1. the interaction of rabbit muscle glycogen phosphorylase b with pairs of ligands has been examined. 2. the electron spin resonance spectrum of a spin label, covalently attached to the protein, provided information about dissociation constants, formation of ternary complexes and both negative and positive interactions between different ligand pairs. 3. amp competes with a series of nucleotides (adp, atp, cmp aand cytosine) but with adenosine a ternary enzyme - amp - adenosine complex can be for ...1976173552
coordinated, coenzyme q reversible, 2,5-dibromothymoquionine inhibition of electron transport and atpase in escherichia coli. 1976174563
murine leukaemia virus expression in the akr following thymectomy.thymectomy effectively prevents the development of spontaneous lymphoma in the akr but how this effect is achieved remains to be determined. one possible mechanism, namely suppression of genomic expression of the oncogenic murine leukaemia virus now seems unlikely since levels of the group specific mulv antigen were in comparision with their sham operated controls unaltered in both neonatally and adult thymectomized akr.1975174705
[selective isolation of a crp (cyclic amp receptor protein)-defective mutant by growth suppression by cyclic amp]. 1975175181
unrelated animal viruses share receptors. 1976175292
[testing the spontaneous impulse activity of an impulse evoked by the synaptic route]. 1975174339
cat leukemia and its viruses. 1975174410
studies on the energetic metabolism of shigella flexneri x escherichia coli hybrids devoid of penetration ability. iii. catalase and phosphatase activity.the catalase and phosphatase activity of avirulent by keratoconjunctival test of guinea pigs lac+, kcp- hybrids that have lost their ability of penetrating in the epithelium, received from virulent strains shigella flexneri (sh. flexneri 222 5a and sh. flexneri m42-43) and donor strains escherichia coli (e. coli k-12, p4x and e. coli h) was investigated. it was established that there is no any dependence between the lost of virulence of the hybrids and the level of the catalase activity. during ...1975175614
mononucleosis-associated subacute sclerosing panencephalitis.a thirteen-year-old girl died of subacute sclerosing panencephalitis (sspe) which occurred as part of a complex encephalitic illness related to acute infectious mononucleosis. the cerebrospinal fluid (csf) epstein-barr virus (ebv) fluorescent antibody (fa) titer was 1:64. electron microscopic examination revealed 17 nanometer (nm) diameter paramyxovirus-like nucleocapsids in brain sections and 90 nm diameter herpes virus-like enveloped particles in negatively stained brain tissue extracts. indir ...1976175632
immunopathogenicity and oncogenicity of murine leukemia viruses. ii. infection of mice and rats with scripps leukemia virus.the pathologic consequences of infection of newborn mice and rats with mulv (scripps leukemia virus--slv) were observed. serum mulv p30 concentrations of most strains were elevated 20 to 100 times that of controls while mulv gp70 levels were elevated only 1.1 to 14.8 times, probably reflecting in part the higher concentrations of gp70 in control sera but also indicating the lack of parallelism in regulation of synthesis of these two viral antigens. infected mice of most strains developed immunol ...1976175661
a radiometric method for predicting effectiveness of chemotherapeutic agents in murine leprosy.a simple radiometric method has been developed for evaluating the effect of drugs on the metabolism of m. lepraemurium. the method is based on the measurement of the 14co2 produced through bacterial metabolism of acetate-u-14c. seventeen drugs were tested: bacitracin, cephaloridine, chloramphenicol, cycloserine, dactinomycin, dds, ethionamide, inh, kanamycin, methenamine mandelate, nitrofurantoin, oxacillin, polymyxin b, rifampicin, streptomycin, sulfadimethoxine and vancomycin. the drugs which ...1975176120
humoral host defense mechanisms against tumors. 1976176124
proceedings: consequences of the two-virus status of the natural mouse lymphatic leukemia viruses. 1975176133
intracellular forms of epstein-barr virus dna in human tumour cells in vivo.tumour biopsies from burkitt lymphoma patients, as well as human nasopharyngeal carcinoma cells growing in athymic mice, contain epstein-barr virus dna as covalently closed circular dna. in addition integrated viral dna sequences seem to be present.1976176597
[pharmacology of airway mechanics]. 1976176708
effects of cytochalasin b on herpes simplex virus type 1 replication. 1976176798
[synthesis of virus-specific macromolecules and virion maturation in chick embryo cells infected with sendai virus].synthesis and accumulation of virus-specific rna, proteins and intracellular nucleocapsids are observed in sendai virus-infected chick embryo cells for approximately 2 days postinfection. however, only an insignificant part of these products leaves the cell as a result of maturation of virus particles. it is suggested that the cause of the ineffective maturation of virions in the system under study may be in the observed instability of one of virus structural proteins in the infected cells, m pr ...1976176819
stimulatory actions of thyrotropin and dibutyryl cyclic amp on transcription and translation in the regulation of thyroidal protein synthesis.when beef thyroid cells were incubated with thyrotropin and then tested for protein synthesizing activity, the stimulatory effect of thyrotropin appeared in two distinct phases: first, an immediate stimulation which continued as long as thyrotropin was present, but died away promptly after withdrawal of the added thyrotropin; and second, a delayed stimulation with a lag period of 1 to 2 h, which persisted after thyrotropin withdrawal. the fast and the delayed effects each stimulated protein synt ...1976177054
immunodeficiency in the chicken. iv. an immunological study of infectious bursal disease.chickens inoculated orally with infectious bursal disease virus (ibdv) 1 day after hatching subsequently showed a 50% incidence of immunodeficiency but little mortality. antibody responses against ibdv and to immunization with sheep red blood cells (srbc) or human serum albumin (hsa) were suppressed. serum igg concentration was decreased while igm occurred exclusively in its 7s monomeric form (migm). an allotypic marker of chicken igm (mla) was lacking in migm derived from ibdv-infected birds. t ...1976177236
hepatomas in grs/a male mice treated with horse serum or horse anti-mouse antilymphocyte serum. 1976177290
[epidemiology of human and animal brucellosis in western africa. the results of six studies in the ivory coast, upper volta, and nigeria].brucellosis has a two-fold importance in public health: the transmission of the disease to man by contact with animals or ingestion of raw milk is of direct importance; of indirect importance is the loss of animal protein. the authors have carried out ten epidemiological investigations in different bio-climatic zones of west africa. more than 120 villages were evaluated. in each village, 100 persons were chosen at random and all or part of the animal population was also studied. three tests were ...1976177324
tissue specific differences in the 2'-o-methylation of eukaryotic 5.8s ribosomal rna. 1975178541
generation of superoxide anion and chemiluminescence by human monocytes during phagocytosis and on contact with surface-bound immunoglobulin g.extent of o-2-release and chemiluminescence, attributed to singlet oxygen, has been compared in human monocytes and neutrophils during phagocytosis, stimulation by the surface-active agent phorbol myristate acetate, or contact with aggregated igg in a model of immune complex disease. monocytes generated o-2-and chemiluminescence with each of the three stimuli, although values were significantly less than those of neutrophils from the same individuals. lymphocytes had no significant activity in e ...1976178824
an in vitro system for studying insulin release caused by secretory granules-plasma membrane interaction: definition of the system.1. an in vitro system is described in which insulin beta-granule-plasma membrane interaction can be studied. 2. the system shows an absolute requirement for physiological amounts of ca2+ (2 mum) in order for insulin release to proceed. 3. atp (5 mum) is abot to augment the ca2+ effect. 4. glucose (17 mm) alone does not cause insulin release but in the presence of ca2+ is as effective as atp. 5. when glucose, atp and ca2+ are added together a positive cooperative effect is produced with over 85% ...1976178856
neurochemical changes in the cat's spinal cord due to orthodromic tetanic stimuli. i: phospholipids.posttetanic potentiation of monosynaptic reflexes has been used as a paradigm for neuronal plasticity. the explanation for this phenomenon is an increased responsiveness of the synaptic junctions. this would basically require chemical changes of the nervous structures involved. the ventral horn area of the spinal cord was therefore analyzed neurochemically. the determination of the phospholipids revealed an alteration of their composition. sphingomyelin, phosphatidylcholine and phosphatidylinosi ...1975178883
mechanism of plasma cyclic amp response to hypoglycemia in man.the effect of insulin-induced hypoglycemia on plasma cyclic amp levels was studied in normal volunteers, adrenalectomized, and sympathectomized subjects. significant increases in plasma glucagon were observed in all groups. normal subjects all had two- to threefold rises in plasma camp while no response was seen in any adrenalectomized or sympathectomized subject. these findings suggest that the mechanism for enhanced plasma camp release during insulin-induced hypoglycemia is catecholamine depen ...1976178982
[effect of migillin on protein synthesis in intact and virally infected tkce and fl cells].the effect of migillin was studied with respect to protein synthesis in the cells of tkce (transplantable line of cells of the kidneys of cow embryos) and fl--intact and infected with viruses of aphtous fever a22, strain 550 and poliomyelitis of type iii, strain saukett respectively. simultaneously the effect of migillin on sensitivity of the cells to the above viruses was tested. the synthesis of protein was determined by incorporation of c14-glycine into the acid insoluble fraction of the cell ...1976179466
[some physicochemical properties of the dysenteric therapeutic--prophylactic newcastle phages h-17 and h-18 (author's transl)].some physico-chemical properties of dysentery therapeutic-prophylactic newcastle-phages h-17 and h-18 were studied. both phages were shown to be resistant to sodium dodecyl sulphate at room temperature. phage h-17 at room temperature was completely inactivated and phage h-18 inactivated by 40% by 1 m sodium hydrochloride. phage h-18 was completely inactivated by 4 m sodium hydrochloride. morphology and sizes of the phages are described. the buoyant density of phage h-17 was found to be 1.497 g/c ...1975174322
[ultramorphometry of cells in a hamster embryo fibroblast culture following transformation by rous sarcoma virus].changes in mitochondria, ergastoplasma and the polyribosomal apparatus of fhe (fibroblasts of hamster embryo) cell culture were studied in the kinetics of their malignification with rous sarcoma virus. considerable alterations were revealed in the organization of protein-synthetising cytoplasmic organells, manifested in the pronounced enhancement of nonspecific protein synthesis and reduction of ergastoplasma. this process starts immediately after the infection and shows a character approximatin ...1975175575
endonucleolytic cleavage of murine leukemia virus 35s rna by microsome-associated nuclease. 1976180996
effect of fluorosteroids on drug response and metabolism. 1976181004
pseudogout: session iii. pathology of cppd crystal deposition: discussion. 1976181018
augmented immunogenicity of tumor cell membranes produced by surface budding viruses: parameters of optimal immunization.membranes prepared from tumor cells infected with surface budding viruses are much more immunogenic than membranes from uninfected tumor cells. factors affecting immunization with membranes from virus-infected tumor cells were studied. preparations made with influenza virus were clearly superior to those prepared with vesicular stomatitis virus (vsv). membranes infected with vsv were maximally immunogenic at a dose equivalent to a 10% cell pack whereas influenza-virus-infected membranes were imm ...1976182646
[infection of hela cells by herpes virus of horses type 1 in different temperature and dose of the virus (author's transl)]. 1976183896
histochemistry of oxidative enzymes in experimental allergic encephalomyelitis.the histoenzymic pattern of oxidative enzymes (g3pd, idh, sd, g6pd,hbd, nadph: dehydrogenase) was investigated in experimental allergic encephalomyelitis (eae) produced in rats according to paterson [13]. the results obtained lead to following conclusions: (1) the neuroglia, including the white matter oligodendroglia of immunized rats, exhibits increased oxidoreductase activities; (2) the neuroallergic reaction induces some stimulation of the oxidoreductive metabolism of oligoden-droglia; (3) th ...1976186370
progesterone in the uterus. v. correlation of the in vitro progesterone metabolism with the progesterone binding in rat uterus.incubations of rat uterine segments with varying 3h-progesterone concentrations were performed to study the hormone uptake by the tissue. the radioactivity of the uterus and the nutrient medium were plotted in form of a scatchard plot. additionally, the binding capacity of the uterine cytosol was measured. in both systems, the hormone was found to be associated with two components which differ from each other in their association constants. the progesterone metabolism occuring at a hormone conce ...1975175525
transfer of parental immunity to infectious laryngotracheitis in chicks.the transfer of parental immunity to infectious laryngotracheitis was appraised by measuring serum antibody levels in 150 chicks from the day of hatch up to five weeks. the breeder flock which had received primary vaccination at eight weeks and a booster at 20 weeks transferred high antibody levels which fell markedly within two weeks and remained constant thereafter. chicks whose parents were vaccinated at 20 weeks only, had low antibody levels throughout. these low levels, in either group of c ...1976187298
inhibition of herpesvirus saimiri replication by phosphonoacetic acid, benzo(a)pyrene, and methylcholanthrene.the present investigations were undertaken to determine the possible effects of two carcinogenic polycyclic aromatic hydrocarbons, benzo(a)pyrene and 3-methylcholanthrene on herpesvirus saimiri replication. the results from these experiments were compared with the effects of phosphonoacetic acid on the virus replication cycle. phosphonoacetic acid inhibited the synthesis of virus-induced intracellular late antigens, membrane antigens and infectious virus but not the synthesis of the early antige ...1977187336
[infections transmitted in swimming pools].public swimmingpools can be the source of infections due to micro-organism such as mycobacterium balnei, adeno and enteroviruses, the virus of plantar warts and molluscum contagiosum, the tric-agent of swimmingpool-conjonctivitis and pathogenic fungi. the transmission of trichomonas vaginalis is considered unlikely-water of pools, supposed to present satisfactory qualities by standard controls, was found to contain pathogenic staphylococci and pseudomonas aeruginosa. effective preventive measure ...1976186978
Displaying items 401 - 500 of 11070