| [the isolation of chlamydia in the male urogenital tract]. | | 1979 | 107412 |
| immunologic functions and in vitro activation of cultured macrophage tumor lines. | five murine monocyte of macrophage tumor lines adapted to culture were characterized for differentiated properties. they ingested zymosan and latex beads, bore receptors for immunoglobulin and complement, synthesized lysozyme (most of which was secreted), and produced granulocyte colony-stimulating activity, either spontaneously or inducibly. some of the lines also mediated phagocytosis and exocytosis of red blood cells (rbc) and lysis of tumor targets, dependent on the presence of specific anti ... | 1978 | 107454 |
| [preparation of extracellular ribonuclease from bacillus subtilis]. | the paper describes a method for isolating alkaline ribonuclease from the culture liquid bacillus subtilis kp 349 which involved: submerged cultivation of the producer on complex and synthetic nutrient media with optimized rnase activity, acid treatment of the total culture liquid, and filtration through perlite. further treatment may include either spray drying of the culture liquid filtrate or its concentration in a vacuum evaporator, dialysis of the concentrate against distilled water, and d ... | 1978 | 107517 |
| [induction of macrophage activation with bacterial products for potentiation of resistance to some chronic infections]. | adult mice of the consanguine a2g strain received two intraperitoneal inoculations of 0.5 mg listeria monocytogenes phospholipid extract at 30 days interval. in the treated animals and the controls, the capacity to develop a humoral immune response was tested 24 hours after the second inoculation, following antigenic stimulus with sheep red blood cells; phagocytizing in vitro of labelled germs by peritoneal macrophages and the response of lymphocytes to mitogenic and allogenic stimuli were likew ... | 1978 | 107569 |
| enteric infections in singapore with special reference to typhoid. | a review of the epidemiological features of the more important enteric infections in singapore was given. enteric fevers (typhoid and paratyphoid), salmonella gastroenteritis and shigellosis remained endemic at a rather constant level in spite of vast improvement in environmental sanitation, but amoebic dysentery showed marked decline. vibrio parahaemolyticus is an important cause of food poisoning since it was first reported in 1973. el tor cholera is believed to be introduced through regional ... | 1978 | 107597 |
| expression of human hepatic genes in mouse hepatoma--human amniocyte hybrids. | human liver-specific gene products are expressed by hybrid cells resulting from the fusion of human amniocytes with mouse hepatoma cells. amniocytes grown from human amniotic fluid have no detectable levels of secreted human albumin, transferrin, alpha-1 antitrypsin, or ceruloplasmin, while the mouse hepatoma line, hh--, secretes several mouse liver-specific gene products including transferrin and albumin. fifty-five hybrids were isolated and analyzed for the expression of serum proteins by ouch ... | 1979 | 107601 |
| frequency and fate of human renal allografts contaminated prior to transplantation. | bacterial cultures were done from donor ureter and/or graft perfusion fluid on 92 of 112 patients who had renal transplantations during 1977. three samples of perfusion fluid and 14 samples of donor ureter contained bacteria. in nine cases there was a gram-positive organism, and in 10 cases a gram-negative rod was (among) the contaminant(s). there was no difference in the rate of graft survival, patient survival, or in the frequency of major postoperative complications between the two groups. on ... | 1979 | 107605 |
| effect of rabbit anti-human thymocyte globulin on lymphocyte subpopulations and functions following allotransplantation in the rhesus monkey. | the survival time of skin allografts from rhla-nonidentical, unrelated donors was increased from a mean of 7.69 days in controls (n = 20) to a mean of 32.53 days in rhesus monkeys (n = 21) receiving a total dose of 250 mg of rabbit anti-human thymocyte globulin (ratg) per kg. immunological monitoring studies were performed on the peripheral blood of mononuclear cells in control and treated monkeys. after administration of ratg, the percentage of e rosette-forming cells (e-rfc) was greater than 9 ... | 1979 | 107631 |
| the viability of cryopreserved aegyptianella pullorum carpano, 1928 in the vector argas (persicargas) walkerae kaiser and hoogstraal, 1969. | | 1979 | 107668 |
| glyconamides as inhibitors of human beta-glucosidases and beta-galactosidases. | | 1979 | 107857 |
| effect of 1,25-dihydroxyvitamin d3 on intestinal calcium absorption in strontium-fed rats. | | 1979 | 107861 |
| spinal cord evaluation by cortical evoked responses. | in ten monkeys, selective segmental lesions of the dorsal columns at the upper thoracic and middle cervical levels resulted in almost total attenuation of the cortical evoked potential responses to peripheral nerve stimulation. conversely isolated segmental dorsal column preservation showed intact transmission of the evoked responses at rostral spinal cord, nucleus ventralis posterior lateralis, and cortical levels. responses recorded from the intralaminar thalamic nuclei in the region of nucleu ... | 1979 | 107931 |
| an enzyme-linked immunosorbent assay (elisa) for detecting chicken anti-reovirus antibody at high sensitivity. | an enzyme-linked immunosorbent assay (elisa) with high sensitivity was developed for use in the avian system. anti-reovirus antibody produced in chickens against the isolants s1133, umi-203, reo-25, and winterfield were detected with this method at high titers (up to 1:14,000). | 1978 | 107949 |
| the respiratory chain of hydrogenomonas h16. | the respiratory chain of hydrogenomonas h16 is shown to consist of two pathways, one of which has as its oxidase and only cytochrome a high-potential b-type cytochrome which is concluded to be cytochrome o. the km values for the oxygen of the two pathways are consistent with the high-potential b-type cytochrome functioning as a relatively high-affinity oxidase. | 1979 | 107951 |
| rna replication: required intermediates and the dissociation of template, product, and q beta replicase. | replication complexes containing only one molecule of q beta replicase and one strand of midivariant rna (mdv-1 rna) template were prepared by incubating the replicase with an excess of mdv-1 (-) rna. in the presence of excess minus strands, these monoenzyme replication complexes were shown to synthesize essentially pure mdv-1 (+) rna in both the first and second cycles of replication. when an equivalent concentration of mutant mdv-1 (-) rna was added to this reaction before completion of the fi ... | 1979 | 107965 |
| the immobilization response in rhesus monkey: a behavioral and electroencephalographic study. | | 1979 | 108127 |
| fascioloides magna: development in selected nonruminant mammalian hosts. | | 1979 | 108129 |
| characteristics of immunoglobulin synthesized early in the development of xenopus laevis. | | 1979 | 108156 |
| the response to lipopolysaccharide of mouse spleen lymphocytes fractionated on the basis of surface immunoglobulin and complement receptor using fluorescence-activated cell sorting and rosetting techniques. | | 1979 | 108210 |
| macaca assamensis as a new host for experimental plasmodium knowlesi infection. | | 1978 | 108217 |
| limitations of aeruginocine typing of ps. aeruginosa as an epidemiological marker. | | 1978 | 108218 |
| repair and late degeneration of the primate foveola after injury by argon laser. | each foveola of nine rhesus monkey eyes was subjected to a single, mild, calibrated exposure from an argon laser (1 to 1.4 mw for 10 to 20 min). observations from ophthalmoscopy, fundus photography, and fluorescein angiography were correlated with light and electron microscopic studies. the ophthalmoscopic changes consisted of initial whitening and subsequent but persistent depigmentation of the foveola. fluorescein angiography showed a pattern consistent with "window defect" of the retinal pigm ... | 1979 | 108229 |
| preparation and antibacterial activity upon micrococcus luteus of derivatives of iturin a, mycosubtilin and bacillomycin l, antibiotics from bacillus subtilis. | methylated and acetylated derivatives of iturin a and mycosubtilin and methylated derivatives of bacillomycin l were prepared and their antibacterial activity on micrococcus luteus was compared with the activity of the original substance. the results obtained show the importance of polar groups for the antibiotic activity of the substances of iturin group. | 1979 | 108238 |
| modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase. | nalidixic acid (nal), a drug which affects deoxyribonucleic acid gyrase activity, inhibits the expression of catabolite-sensitive genes: the three maltose operons, the lactose and galactose operons, and the tryptophanase gene. a correlation between the degree of sensitivity to nal and that to catabolite repression has been observed. the expression of the threonine and tryptophan operons, insensitive to catabolite repression, is insensitive to nal. the expression of the lacz gene under the contro ... | 1979 | 108253 |
| demonstration and characterization of specific binding sites for factor viii/von willebrand factor on human platelets. | the presence of specific factor viii/von willebrand factor (fviii/vwf) binding sites on human platelets has been demonstrated by using 125i-fviii/vwf and washed human platelets. binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from 0.2 to 1 mg/ml. binding of 125i-fviii/vwf to platelets can be competitively inhibited by unlabeled human or bovine fviii/vwf, but not by human thrombin, fibrinogen, alpha 2-macroglobulin, equine collagen, or a lectin of ri ... | 1979 | 108291 |
| effect of n-trifluoroacetyl derivatives of amino acids and amino acid analogs on microbial antitumor screen. | eighteen trifluoroacetyl derivatives of amino acids and of amino acid analogs were prepared and tested for growth-inhibitory activity using a lactobacillus casei system as a prescreen for antitumor activity. of the compounds tested, the trifluoroacetyl derivatives of o-, m-, and p-fluorophenylalanine and of beta-3-thienylalanine showed modest activity; trifluoroacetyl derivatives of phenylalanine and of beta-2-thienylalanine showed marginal activity. the activity exhibited by the active trifluor ... | 1979 | 108385 |
| [tuberculosis and changes in the tissue lipids]. | | 1979 | 108447 |
| pantothenase. | | 1979 | 108511 |
| isolation of an influenza virus subtype hav4navl from a budgerigar. | | 1979 | 108521 |
| response of periapical pathosis to endodontic treatment in monkeys. | response of induced periapical lesions in monkeys to a conventional endodontic technique was investigated at varying periods ranging from 15 to 365 days after treatment. the findings indicate that response to treatment is influenced by the extent of the root canal filling, the time lapse between treatment and death, and the presence or absence of bacteria in the apical portion of the canal. | 1979 | 108648 |
| [effect of microsporidiosis on the fertility of aedes caspius caspius (culicidae) mosquitoes]. | effect of microsporidiosis on the fecundity of hosts a. c. caspius was studied. the calculation of eggs in hatches has shown that females developing from infected eggs lay 2--3 times lesser eggs than non-infected ones. besides, the number of females laying eggs decreases considerably. despite the females of mosquitoes suck blood before each egglaying the disease, which proceeds at their larval stage, affects greatly their fecundity. additional feeding of females cannot compensate completely the ... | 1979 | 108654 |
| polydipsia in the monkey generated by visual display schedules. | | 1979 | 108693 |
| the effects of alcohol on agonistic behavior in the telomian dog. | the study analyzed the effects of alcohol on agonistic behavior in three independent social systems, each compromised of two male and one female telomian dog. three dose levels were used: 0, 0.8, and 1.6 g/kg body weight of absolute alcohol diluted to 20%. observations were made when none, one (top, middle or low ranking), or all dogs in a system received a given treatment. at the 0.8 g/kg level, low ranking dogs showed an increased frequency of attacks and bone possession time, while top and mi ... | 1979 | 108707 |
| piracetam facilitates retrieval but does not impair extinction of bar-pressing in rats. | rats were trained on a continuously reinforced bar-press response for water reward. seven days later they were retested for retention, with or without pretest injection of the nootropic drug, piracetam. drug-treated animals had significantly shorter response latencies than saline-treated animals. the results are interpreted as a facilitation of retrieval processes after forgetting. the experiment was extended under extinction conditions and it was found that after three sessions there was a tend ... | 1979 | 108722 |
| sex differences in behavioral and thermal responses to pargyline and tryptophan. | the effects of parenterally injected pargyline and tryptophan on rectal temperature and behavior have been studied in male and female rats. pargyline alone (50 mg/kg) produced hypothermia in both sexes. pargyline (50 mg/kg) followed by low doses (20--50 mg/kg) of tryptophan caused a behavioral syndrome consisting of tremor, hindlimb abduction, forepaw treading, and straub tail. in females, but not in males, hypothermia was potentiated. the same dose of pargyline followed by higher doses (60--150 ... | 1979 | 108723 |
| dietary modification of amphetamine stereotyped behaviour: the action of tryptophan, methionine, and lysine. | rats fed diets high in tryptophan, methionine, and tryptophan plus methionine or lysine were subsequently injected with 10 mg/kg d-amphetamine. the amount of amphetamine-induced stereotyped behaviour observed varied as a function of the dietary addition, with methionine showing the greatest difference to controls, and lysine the least. whole brain catecholamine levels and 5-hydroxytryptamine levels also showed amino acid-specific changes. | 1979 | 108724 |
| comparison of the discriminative stimulus properties of nefopam and morphine. | separate groups of rats were trained to discriminate nefopam or morphine from saline in a two-lever operant task. nefopam produced saline-appropriate responding in morphine-trained rats. the highest dose of morphine tested in nefopam-trained rats produced responding appropriate for neither training treatment. this intermediate morphine responding was antagonized by a naloxone treatment that had no effect on the nefopam discrimination. these results suggest that the stimulus properties of nefopam ... | 1979 | 108741 |
| cardiac imaging with tantalum-178. | tantalum-178 is a potential tracer for the first transit studies of the heart. it has a short physical half-life (9.3 minutes) and is obtained as a generator product from its long-lived (21.3 days) parent, tungsten-178. first transit studies were performed in the monkey and dog following the intravenous injection of 20 mci (740 mbq) of tantalum-178. imaging was performed with a large field of view single crystal camera and a multicrystal camera. pulmonary dilution curves were derived for the ana ... | 1979 | 108764 |
| [note about the biology of cuterebra apicalis (guérin, 1829/38) (diptera-cuterebridae) (author's transl)]. | this note reports the parasitism by cuterebra apicalis guérin (1829/1838) on the rodents oryzomys eliurus and calomys callosus collected in the north of formosa county, goiás state. the infested animals were kept in the laboratory to allow observations on the development of the parasite. | 1978 | 108773 |
| subsets of t lymphocytes and lymphocyte cooperation. modulation of the immunocellular response. | recent advances in the characterization of t cell subsets suggests that the various subsets of t cells described in mice also occur in man. these various subsets of t cells can be detected by the use of appropriated antisera, co-cultivation of purified lymphoid cell preparations and differential sensitivity to radiation. clinical applications from these new observations are now underway and it is hopeful that they should help to achieve a better understanding of the mechanisms responsible for au ... | 1979 | 111313 |
| [antibacterial immunity in diphtheria. experimental research]. | a number of 700 guinea pigs were immunized by parenteral route with non-toxigenic corynebacterium diphtheriae strains, then inoculated with various doses of homologous and heterologous toxigenic c. diphitheriae strains. the results showed that non-toxigenic c. diphtheriae strains confer a certain degree of protection when the challenge is done with homologous toxigenous strains, especially when not more than 500 million germs/ml are used for the challenge dose. this suggests that the carriage of ... | 1979 | 111333 |
| [rapid methods useful for determination of streptococcal groups with special reference to streptococci of groups b and d]. | a study was carried out on the efficiency of certain rapid methods for the identification of streptococcal groups, especially groups b and d, methods based upon physiologic properties such as hippurate hydrolysis, production of pigment, esculin hydrolysis, tolerance to salt and bilolysis, associated with the classical tests, for instance the hemolysis type and sensitivity to bacitracin and optochin. by these tests, accessible to hospital laboratories, a number of 3083 streptococcal strains were ... | 1979 | 111335 |
| methylation status of intracellular dengue type 2 40 s rna. | | 1979 | 111410 |
| vasopressin release and drinking induced by intracranial injection of angiotensin ii in monkey. | the effects of intracerebral injection of angiotensin ii (aii) on both water intake and arginine-vasopressin (avp) release were tested on unanesthetized rhesus monkeys (macaca mulatta). injection of 10(-10) mol of peptide was administered with a cannula microinjection system stereotaxically implanted into different diencephalic structures. the preoptic area, anterior part of third ventricle, caudate nucleus, and septum appeared to be the injection sites most effective in eliciting both drinking ... | 1979 | 111563 |
| a craniometric study of the black and white colobus illiger 1811 (primates: ceropithecoidea). | this study examines the craniometry of black and white colobus monkeys using 1072 specimens representing all the recognized subspecies (after rahm, '70) of the genus. seventy-six measurements were taken on each individual, and examined using canonical variates analysis and clustering by ward's error sum method. the assumptions of the analytical techniques are shown to be met, and the results demonstrated to be stable. examination of the populations for statistical difference and taxonomic distin ... | 1979 | 114059 |
| lipid a from endotoxin: antigenic activities of purified fractions in liposomes. | isolation of lipid a by acid hydrolysis of shigella flexneri lipopolysaccharide resulted in a product that consisted of a heterogeneous mixture of bands when visualized by thin layer chromatography. differential extraction with ethyl acetate and chloroform, or extraction with edta, followed by chloroform-methanol-water (bligh-dyer extraction), or a combination of both extraction schemes, resulted in partial purification of immunologically active lipid a. eight fractions were purified further by ... | 1979 | 115918 |
| effects of methamphetamine and scopolamine on variability of response location. | methamphetamine and scopolamine were studied in monkeys responding under a multiple fixed-ratio fixed-interval schedule of reinforcement. a response on any one of six levers could satisfy the schedule requirements. variability of response location was evaluated in terms of switches, where a switch was defined as a response on one lever followed by a response on a different lever. under baseline conditions the fixed-ratio schedule generated a high rate of responding and a low level of variability ... | 1979 | 115956 |
| sensitization of myelinated nociceptive afferents that innervate monkey hand. | | 1979 | 115969 |
| sugar hydrolases and their arrangement on the rat intestinal microvillus membrane. | the arrangement of the sugar hydrolases, sucrase-isomaltase, maltase, and lactase on the microvillus membrane of rat intestine was investigated by immunological technique. the enzymes were purified essentially free of each other to near homogeneity and antisera of high specificity were obtained against each. microvillus membranes were prepared routinely in high purity from rat intestine and contained an average 61% protein, 20% lipid, and 19% carbohydrate, with the sugar hydrolases comprising an ... | 1979 | 116006 |
| folacin deficiency and requirement in the squirrel monkey (saimiri sciuresus). | acute folacin deficiency was studied in eight young squirrel monkeys (saimiri sciureus). half of the animals were fed a semipurified deficient diet (no added folic acid) and half were fed a control diet (0.84 mg of added folic acid per kilogram of dry diet). monkeys fed the deficient diet lost weight and suffered from diarrhea and dehydration leading to the death of one of the animals after 6 weeks. folacin deficiency also was studied in six older animals fed diets containing varying levels of a ... | 1979 | 116540 |
| accidental contamination of diagnostic cultures of mycobacteria and phage identification of the contaminating strain. | phage typing of mycobacteria is a new technique not yet widely used for classification and intraspecies differentiation. systematic long-term studies organized by the who have succeeded, using a battery of 11 different mycobacterial phages, in dividing m. tuberculosis into 3 different phage sub-groups, preliminarily labelled as a, b and c. a special case of phage-typing is presented which enabled identification of a virulent mycobacterial strain causing accidental contamination of diagnostic myc ... | 1979 | 117577 |
| [the effect of lh releasing hormone on testosterone levels in the blood of boars with sexual dysfunctions]. | the levels were assessed of testosterone in the blood plasma before and 90 minutes after i.v. application of 1 mg of synthetic lh-releasing hormone to 57 boars with disorders of sexual functions and to 43 boars without sexual dysfunctions. the group of animals with sexual disorders included boars with inferior ejaculate quality and low fertility (24 animals) and cases with disturbed sexual potency (33 boars). in animals with the studied changes of sexual functions, compared with boars without se ... | 1979 | 117601 |
| the progressive nature of neoplastic transformation of syrian hamster embryo cells in culture. | | 1979 | 119980 |
| annotations on the measurement of liver ferritin, especially in the rat. | | 1979 | 120687 |
| [evaluation of the myeloculture by puncture of the ilium crest for isolation of brucella from patients with brucellosis]. | hemocultures and myelocultures of samples obtained from the ilium crest were made simultaneously of 61 patients with serologic diagnosis of brucellosis. five strains were isolated by both methods and 18, by myeloculture only. all samples from which brucella were isolated by hemoculture were also positive by myeloculture. the advantages of making myelocultures of patients previously treated with antibiotics are emphasized. | 1979 | 122390 |
| dynamic determinants of letf ventricular diastolic pressure-volume relations in man. | left ventricular (lv) diastolic pressure (p), volume (v), and rate of change of volume (dv/dt) were determined at 16.7 msec intervals in 17 patients (simultaneous micromanometer and single plane volume angiography). four patients had mitral stenosis with atrial fibrillation and 13 patients (three normal, two congestive cardiomyophathy, three lv hypertrophy, and five coronary artery disease) were in normal sinus rhythm. maximum early diastolic filling rates (max dv/dt) in the normal and cardiomyo ... | 1975 | 122921 |
| [endemic dysentery in psychiatric institutions, exemplified by the land hospital, schleswig, for child-and adolescent-psychiatry (author's transl)]. | | 1975 | 123321 |
| [effects of caudate nucleus stimulations on the primary and secondary endings activity of soleus muscle spindle]. | effects of repetitive stimulation of the contralateral caudate nucleus on the static discharge and dynamic sensitivity of soleus muscle spindle primary and secondary endings were studied in cats anaesthetized with halothane (fluothane). by progressive increasing the depth of anaesthesia two different fusimotor effects could be observed. 1. a static facilitatory effect; under light anaesthesia the static discharge of primary and secondary endings were strongly increased. the response of the prima ... | 1975 | 123860 |
| intramyocardial pressure: effect of preload on transmural distribution of systolic coronary blood flow. | impairment of systolic coronary blood flow (cbf) may be mediated by intramyocardial pressure (pim). however, the effect of systole on the magnitude and transmural distribution of coronary blood flow has not been investigated. the purpose of this study was to measure this effect, and, indirectly, intramyocardial pressure. it is assumed that intramyocardial pressure acts on the coronary vessels as a starling resistor, such that local coronary blood flow is determined by the equation: coronary perf ... | 1975 | 124128 |
| hepatic mitochondrial function in ketogenic states. diabetes, starvation, and after growth hormone administration. | the study was designed to evaluate hepatic mitochondrial function during ketotic states. the ketogenic models studied were streptozotocin-induced diabetic ketoacidosis, 48 h of starvation, and after growth hormone administration. in the last-mentioned model we observed increased free fatty acids but not ketonemia. oxidative phosphorylation was measured using the citric acid cycle substrates pyruvate and succinate, the amino acid glutamate, a ketone body beta-hydroxybutyrate, and a long-chain fat ... | 1975 | 124319 |
| effects of n-ethylmaleimide on the atpase activities of cardiac myosin from thyrotoxic rabbits. | | 1975 | 124376 |
| [possible causes determining the developmental rhythm of populations of the nasopharyngeal gadfly of sheep, oestrus ovis l. (diptera, oestridae)]. | on the basis of observations undertaken in azerbaijan and available literary data the author considers the hypotheses concerning the reasons causing the delay of the ist instar larvae development and determining the age structure changes in population of oestrus ovis l. within a year. the main reasons are as follows: factors depending on the population density at the larval phase, the light day duration within the life cycle of the botfly females. | 1975 | 124845 |
| stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro. | august and wistar rat lymph node cells were found to respond well to pha stimulation and in mixed lymphocyte culture, as determined by an increased incorporation of 3h-thymidine. august rat lymph node cells were also stimulated by incubation with irradiated syngeneic tumour cells. allogeneic wistar rat lymph node cells produced a larger response to the august tumour cells. the response of syngeneic and allogeneic lymph node cells was reduced by pretreating the tumour cells with a wistar anti-tum ... | 1975 | 126072 |
| cytochemical identification of atpase-positive langerhans cells in edta-separated sheets of mouse epidermis. | sheets of epidermis for incubation to demonstrate atpase activity were obtained from specimens of mouse footpad using edta as the separation medium. the use of edta in place of the nabr method previously described, resulted in a greatly reduced incubation time, precise localization of reaction product and preservation of ultrastructural detail. a population of closely and regularly spaced atpase-positive dendritic cells was demonstrated by light microscopy. electron microscopy demonstrated that, ... | 1975 | 126073 |
| [clinical conference: histamine and basophils after cellular separation on albumin gradient]. | | 1975 | 126441 |
| interactions of the third component of complement (c3) with cross-linked dextran. iii. isolation and characterization of interacting components after enzymatic digestion of complement coated cross-linked dextran. | in previous investigations we could show that incubation of cross-linked dextran (sephadex) with normal human and normal guinea pig serum results in the binding of c3 to sephadex. this binding was found to be due to activation of c3 via an alternate pathway. in this paper data are presented which show that components bound to sephadex can be recovered after enzymatic digestion of serum-reacted sephadex beads. the digests were characterized with immuno-electrophoresis and double immunodiffusion t ... | 1975 | 126570 |
| effect of methysergide, a blocker of serotonin receptors, on plasma prolactin levels in lactating and ovariectomized rats. | the effect of methysergide (mes, 2.5 mg/100 g body wt), a serotonin antagonist, on prolactin release has been studied in lactating and ovariectomized rats. mes caused significant increases in prolactin release in both animals. studies in ovariectomized, hypophysectomized rats indicate that this effect is not due to a decrease in the peripheral metabolism of prolactin. in vitro incubations of anterior pituitary fragments with mes failed to demonstrate any increase in prolactin release, suggesting ... | 1975 | 126860 |
| characterization of 5.8s ribosomal ribonucleic acid in neurospora crassa. | neurospora crassa ribosomes contain a species of ribonucleic acid (rna) of molecular weight 54,000, similar to 5.8s ribosomal rna previously described for other eukaryotic organisms. the 5.8s rna from n. crassa was found to be released by heat treatment at 60 c from 25s ribosomal rna but not from 18s ribosomal rna. the base composition of n. crassa 5.8s rna was similar to that of 5.8s rna from saccharomyces cerevisiae, but differed from animal 5.8s rna. during the course of this study, it was di ... | 1975 | 126993 |
| purification and properties of membrane-bound coupling factor-latent atpase from mycobacterium phlei. | the membrane bound coupling factor-latent atpase was solubilized from the membrane vesicles of mycobacterium phlei by using 0.25 m sucrose or low ionic strength buffer. purification of the solubilized enzyme by use of sepharose-adp conjugate gel yielded a homogenous preparation of latent atpase which was purified about 216-fold in a single step with an 84% yield. the enzyme exhibits a specific activity of 39 mumoles of atp hydrolyzed per min per mg protein. the purified enzyme exhibits coupling ... | 1975 | 127086 |
| the significance of coronary arterial stenosis during cardiopulmonary bypass. | myocardial infarction may develop during an uneventful open-heart operation. in order to better understand this complication, we undertook an experimental study. the left circumflex coronary artery of 20 dogs was narrowed to 50 per cent of its area by a metal screw clamp to produce a localized coronary stenosis. regional myocardial perfusion in the distribution of both the stenotic circumflex and normal left anterior descending (lad) coronary arteries was measured by injection of a radioactive-l ... | 1975 | 127092 |
| the hurler syndrome: treatment of cultured hurler fibroblasts with normal human serum. | prolonged replacement of fetal calf serum by normal human serum for the enrichment of medium during tissue culture of hurler fibroblasts resulted in increased acid mucopolysaccharides in the cells and in the medium. the predominant intracellular mucopolysaccharide had the characteristics of dermatan sulfate when hurler cells were treated with either serum. normal human serum contains a nonspecific coreective factor capable of augmenting the loss of 35so4-amps from hurler cells, but not from norm ... | 1975 | 127180 |
| arthrosonography: gray-scale ultrasound evaluation of the shoulder. | gray-scale ultrasound images of the shoulders of 6 rhesus monkeys were obtained before and after fluid instillation to assess the ability of ultrasound to diagnose joint disorders. the normal bony landmarks and muscular structures were shown. after the fluid was introduced, fluid collections were identified in the axillary pouch and subscapular bursa. ultrasound is a promising new method of detecting intra-articular effusions of the shoulder. | 1979 | 111302 |
| comparative behavioral effects of clorgyline and pargyline in man: a preliminary evaluation. | the antidepressant and other behavioral effects of clorgyline, a preferential inhibitor of monoamine oxidase (mao) type a, were compared with those of pargyline, a preferential inhibitor of mao type b, in 16 depressed patients. in a subgroup of more severely depressed patients, clorgyline treatment for 4 weeks resulted in significant improvement on both observer-rated and self-rated scales, while minimal changes occurred during pargyline treatment. similarly, in a crossover study that included 8 ... | 1979 | 111274 |
| distribution of visual and somatic functions in the parietal associative area 7 of the monkey. | | 1979 | 109170 |
| enhanced 5-hydroxytryptamine-mediated behavioural responses in rats following repeated electroconvulsive shock: relevance to the mechanism of the antidepressive effect of electroconvulsive therapy. | treatment of rats with one electroconvulsive shock (ecs) per day for 10 days enhanced the hyperactivity syndrome produced by administration of tranylcypromine (10 mg kg-1) and l-tryptophan (50 mg kg-1) given 24 h after the final shock. similar enhancement was seen whether the shock was alternating sinusoidal or direct current (fractionated), whether it was given through unilaterally or bilaterally placed electrodes and whether or not a neuromuscular blocking agent (fazadinium) was used. five sho ... | 1979 | 108733 |
| direct and utilization of metabolic energy for transport processes within proximal convolution. | | 1975 | 127689 |
| immunologic relationship among fibrinolysins secreted by cultured mammalian tumor cells. | | 1975 | 127717 |
| prevention of thrombosis after small artery endarterectomy, with dextran and fibrinolytic agents. | | 1975 | 127798 |
| human muscle spindles: fine structure of the primary sensory ending. | the primary sensory innervation of muscle spindles obtained by muscle biopsy of normal human volunteers was studied with the light and electron microscopes. the parent ia sensory fibre branched 4-6 times, became unmyelinated for 25-30 mum, then formed sensory terminals on each nuclear bag and chain intrafusal muscle fibre. the first 4--5 mum of the unmyelinated segment is believed to be an encoder zone because the plasmalemma was undercoated by a dense granular layer similar to that under other ... | 1975 | 127831 |
| observations on epizootiology and distribution of elaeophora schneideri in montana ruminants. | seventy-four moose, 111 elk, 20 mule deer, 8 white-tailed deer, 26 prong-horn antelope, 42 domestic sheep and 3 bighorn sheep from montana or northwestern wyoming were examined post-mortem for evidence of elaeophora schneideri infection in 1973-74. fifteen percent of the mule deer and four percent of the moose were positive for adult arterial worms. this constitutes the first report of e. schneideri in mule deer in montana. no gross signs of blindness or other neurologic disorder were evident in ... | 1975 | 127848 |
| microautoradiographic study of cell proliferation in compensatory renal growth. | dna synthesis in the renal parenchyma was studied by electron microscopic autoradiography 48 and 72 hours after unilateral nephrectomy in mice and weanling rats. the proportion of labelled nuclei belonging to the epithelium, endothelium, interstitial areas, or circulating cells was evaluated. most of cells showing dna synthesis were epithelial but many belonged to stroma. all the nephron segments were found to participate in compensatory hyperplasia, with a greater contribution, however, of the ... | 1975 | 127941 |
| identification and actions of gastric inhibitory polypeptide. | | 1975 | 128084 |
| physiopathological aspect of glynn's type of experimental arthritis. | knee joint arthritis is induced among rabbits previously immunized by intradermal injection with egg albumin (ea) emulsified in adjuvant containing either m. tuberculosis or m. butyricum, then by intra-articular injection with ea. arthritis evolution involves two phases, an early one during the first 2 months and a late one from 3 months to 1 year. during the early phase, arthritis intensities are similar no matter which mycobacterium is used. however, during the late phase, only rabbits immuniz ... | 1975 | 128112 |
| [solubility of the mg2+-dependant ca2+-activated atpase fraction of the plasma membranes of synaptosomes]. | mg2+-dependent ca2+-activated atpase (mg2+,ca2+-atpase, ec 3.61.4) in the fraction of synaptosome plasmatic membranes is activated with 0.05-0.08% solutions of digitonin and sodium deoxycholate. at higher concentrations of digitonin the activating effect lowers, sodium deoxycholate in the increasing concentrations inactivates the enzyme. 0.08% digitonin activates mg2+,ca2+-atpase of synaptosome membranes, without demanding for its transition into solubilized state. separation of non-active 0.08% ... | 1975 | 128171 |
| [enzymatic properties in muscle membranes]. | a study in the enzymatic properties of muscle membranes established that sarcolemma of the rabbit skeletal muscles contains the ca2+-atpase system which does not require mg2+ for manifestation of ions activity. by some kinetic properties it differs from atpase of myosin. the complex ca-atp2+ is a substrate of ca2+-atpase. ions of a series of bivalent metals inhibit the latter as well as the passive transport of ca2+, that may evidence for a definite relation of ca2+-atpase with ca+2 transport in ... | 1975 | 128174 |
| [changes in the lungs and the mass of the right ventricle of the heart in chronic hypoxia (experimental-morphological study)]. | in experiments on 105 white rats using histological, histochemical, and morphometric methods the state of the lungs following daily "rises" in a pressure chamber to the "hight" of 5000--9000 m at verious time intervals--from 1 day to 9 weeks was studied. in 18 animals "ascents" were preceded by sinistral pulmonectomy. in parallel, the heart was investigated by the method of separate weighing. at initial stages changes in the lungs were characterized predominantly by impairment of the blood- and ... | 1975 | 128341 |
| the effect of butacaine on adenine nucleotide binding and translocation in rat liver mitochondria. | the effect of the local anaesthetic, butacaine, on adenine nucleotide binding and translocation in rat liver mitochondria partially depleted of their adenine nucleotide content was investigated. the range of butacaine concentrations that inhibit adenine nucleotide translocation and the extent of the inhibition are similar to the values obtained for native mitochondria. butacaine does not alter either the total number of atractyloside-sensitive binding sites of depleted mitochondria, or the affin ... | 1975 | 128352 |
| [classification of white, coagulase-negative staphalococci by means of lysotyping]. | | 1975 | 129044 |
| ischemia-induced alterations in myocardial (na+ + k+)-atpase and cardiac glycoside binding. | the effects of ischemia on the canine myocardial (na+ + k+)-atpase complex were examined in terms of alterations in cardiac glycoside binding and enzymatic activity. ability of the myocardial cell to bind tritiated ouabain in vivo was assessed after 1, 2, and 6 h of coronary occlusion followed by 45 min of reperfusion, and correlated with measurements of in vitro (na+ + k+)-atpase activity and in vitro [3h]ouabain binding after similar periods of ischemia. regional blood flow alterations during ... | 1976 | 130383 |
| [an outbreak of dysentery caused by sh. flexneri var. x]. | | 1975 | 130767 |
| [newly detected relationships between antibacterial activity and structure of some chalocones]. | | 1976 | 130785 |
| the separation and reactivity in vitro of a subpopulation of human lymphocytes which bind histamine. correlation of histamine reactivity with cellular maturation. | | 1976 | 132992 |
| the effect of increased brain gaba produced by amino-oxyacetic acid on arousal in rats. | previous work has reported behavioral arousal in the rat to be inversely related to cortical gaba production. therefore the effects of an increase in brain gaba levels, induced by amino-oxyacetic acid, on measures of behavioural arousal such as rearing and ambulation were examined. the increase in gaba was immediately associated with decreased rearing, however the behaviour was later indistinguishable from control values while the levels of brain gaba remained raised. it was suggested that the r ... | 1976 | 134388 |
| effects of exercise training and exhaustion on 45ca uptake by rat skeletal muscle mitochondria and sarcoplasmic reticulum. | mitochondrial and sarcoplasmic reticular 45ca2+ uptake and ca2+-atpase activity were determined in skeletal muscle from exercise trained and non-trained rats at rest or following short-term exhaustive exercise. in trained rats exercised to exhaustion, mitochondrial 45ca2+ uptake was significantly depressed when compared to non-trained rats at rest. ca2+-atpase activity of sarcoplasmic reticulum from trained rats exercised to exhaustion was significantly increased as compared to trained rats at r ... | 1976 | 134437 |
| [synchronous electric activity with inspiration in the vastus lateralis muscle of the anesthesied dog breathing spontaneously]. | in the dog, under chloralose or pentobarbitone anesthesia and breathing spontaneously, a muscular electrical activity of low voltage synchronous with respiration was observed in m. vastus lateralis. the mean maximum amplitude of this activity is inversely linked with respiratory rate. when the respiratory frequency is equal or exceeds 25 cycles per minute this activity disappears. such a phenomenon seems to be related to the activity of the respiratory centre. | 1976 | 134813 |
| site of hydrolysis of collagen by hot trichloroacetic acid. | when calfskin collagen is treated with trichloroacetic acid at 90 degrees c, it is hydrolyzed to a mixture of peptides, some of which are quite small. cleavage of collagen by acid seems to occur at bonds between proline (or hydroxyproline) and other amino acids, with only a limited specificity for which amino acid donates its amino group to the susceptible peptide bond. | 1976 | 134865 |
| dynamics of sulfonylurea-induced insulin release from the isolated perfused rat pancreas. | in the isolated perfused rat pancreas various sulfonylurea drugs were tested with a basal glucose level of 1 mg/ml in the perfusion buffer and were found to cause a biphasic insulin response. novocs 476, a new and potent sulfonylurea, and glibenclamide qualitatively differed from tolbutamide, glibornuride, glipizide, and glisoxepide, which were all alike in terms of the relationship between first and second phases of insulin release. | 1976 | 134920 |
| control of synthesis of mrna's for t4 bacteriophage-specific dihydrofolate reductase and deoxycytidylate hydroxymethylase. | a 30 degrees c, functional messengers for dcmp hydroxymethylase first appeared 3 to 6 min postinfection and reached their maximum levels at 12 min. chloramphenicol, added before the phage, reduced the rate of mrna accumulation. when the antibiotic was added 6 min postinfection, mrna levels increased at their normal rate but there was no obvious repression of messenger accumulation. delaying the addition of drug until 8 or 12 min had progressively less effect on the pattern of hydroxymethylase mr ... | 1976 | 135096 |
| [tuberculosis in domestic animals and its relationship with human tuberculosis]. | | 1976 | 135254 |
| [comparative study on lymphocyte stimulation by pha and bacterial endotoxins, particularly in malignant tumor and allergy patients]. | in a group of 37 tumor patients with predominantly advanced disease, lps stimulation (lps of sh. sonnei and sh. flexneri) resulted in a significant increase of the transformation rates caused, most probably, by the high proportion of b cells. on the other hand, allergics (drug allergies) did not differ from controls. it seems possible that b cell stimulation by bacterial endotoxins can be used for the assessment of the reactivity of the organism. | 1976 | 135504 |