PMID(sorted ascending)
artificial gut in gastrointestinal cancer. 1997499993
[diagnostic measures in nuclear medicine. 1. diagnosis of kidney diseases]. 2004511058
2,3,7,8-tetrachlorodibenzo-p-dioxin: covalent binding of reactive metabolic intermediates principally to protein in vitro.2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) is metabolized by the mouse liver cytochrome p-450-mediated monooxygenase system to reactive intermediates which bind 'covalently' to cellular macromolecules. although very difficult to quantitate, the presumably covalent binding to microsomal protein occurs between 120 and 2,640 times more readily than binding to deproteinized dna in the in vitro reaction. because of the extremely high rate of binding to protein rather than to dna, it is visualized tha ...1979515166
[effectiveness of psychotherapy in the treatment of adolescents]. 2004515252
[risk involved in decision to change genital gender, illustrated by a case report]. 2004515256
firing of horses. 1979516355
prenatal and intrapartum high-risk screening. ii. risk factors reassessed.a method of identifying the high-risk pregnancy by a quantitative assessment of prenatal, intrapartum, and neonatal factors is presented. calculating the probabilities of neonatal risk can be done with a hand-held calculator. the technique described provides a method of assessing the importance of perinatal variables and determining the effect of the process of health care on outcome.2004517589
microelectrode artifacts and frog skin potentials. 2004522131
regeneration of cervical epithelium following laser destruction of intraepithelial neoplasia. 2004523042
medico-legal aspects of private practice. 2004523561
against the tide. 2004523565
[analysis of the structure of the sinus rhythm in the diagnosis of a rheumatic heart lesion in children]. 2004524779
the effect of the electromagnetic field and 0,0-diethyl-0-1-(2,4-dichlorphenyl)-2-bromovinylphosphate and 0,0-dimethyl-3-1-(2,4-dichlorphenyl)-2-bromovinylphosphate on the survival of balantidium coli (malmsten). 1979524894
hemophilia--a challenge for the nurse anesthetist. 2004525232
complications at balloon catheter angiography. experiments in rabbits and dogs.overdistension of a balloon catheter may injure an artery and this risk increases with decreasing vessel calibre. before balloon occlusion an estimation of the calibre of the vessel at a preliminary angiography is recommended.1979525401
responses of supraoptic neurones to local hypertonic saline in the rat [proceedings]. 1979529135
thombocyte function in relation to the long term application of medroxyprogesterone acetate as a female contraceptive agent. 2004529167
[use of biguanides in the treatment of diabetes. (official information from the drug commission of the union committee for labor, health, and social welfare)]. 2004531665
[patellectomy: indications and long-term results (author's transl)]. 2004532010
physical studies of cell surface and cell membrane structure. deuterium nuclear magnetic resonance investigation of deuterium-labelled n-hexadeconoylgalactosylceramides (cerebrosides).1. deuterium fourier transform nuclear magnetic resonance spectra of a series of n-palmitoylgalactosylceramides (cerebrosides) specifically labelled with deuterium at one of positions 2', 6', 10' and 16' of the acyl chain, or in the c-6 hydroxymethyl group of the galactose residue, have been obtained using a spin-echo technique at 34.1 mhz with a homebuilt superconducting magnet spectrometer. 2. the effects of temperature and cholesterol on the deuterium spectra have been investigated. the resul ...2004534624
kinetic properties of the purified 3-hexulosephosphate synthase from pseudomonas oleovorans.the kinetic characteristics of the purified 3-hexulosephosphate synthase from the facultative methylotroph pseudomonas oleovorans were investigated. it could be demonstrated that the dependence of the reaction rate on the rib(ul)ose-5-phosphate as well as the formaldehyde concentration has a complex shape with the appearence of plateau and trough regions. the shape of the curve is changed in dependence on the fixed level of the second substrate. multiple forms of the 3-hexulosephosphate synthase ...1979538957
a sensitive fluorimetric microassay for the determination of glutathione peroxidase activity. application to human blood platelets. 1979543550
effect of a mixture of cryoprotectants in attaining liquid nitrogen survival of callus cultures of a tropical plant. 2005544179
[osteomyelitis]. 2005544236
[vaccination against measles, mumps and rubella--together or separately?]. 2005544244
[the excretory apparatus and diabetes]. 2005545627
[lesion of the collateral ulnar ligament of the thumb]. 2005546527
[influence of phenobarbital on hyperbilirubinemia caused by nicotinic acid and rifamycin--sv in healthy subjects].ten healthy subjects have been given before and after treatment with phenobarbital the following intravenous charges: a) nicotinic acid; b) rifamicyn-sv; c) simultaneous administration of the two drugs. along with confirmatory evidence of the wellknown increase in bilirubinaemia (prevalently unconjugated), we have observed phenobarbital to attempts partially yet significantly that effect. on the base of direct experience on rat liver, we hypothise phenobarbital to increase the pool of the y prot ...1979548051
[inhibitory effects of indomethacin on prolactin liberation induced with peptides with opium-like activity].indomethacin inhibits prolactin liberating effects by met-enkefalin-nh2, a synthetic analogue of met-enkefalin, both in intact and in ovariectomized, estradiol benzoate treated rats. the introduction of pge1 increases the intensity of this effect. it is therefore possible to suppose that the pgs are involved as intermediaries of the prolactin relasing effect induced by met-enh-nh2.1979548065
[cutaneous evaporimetry. ii. the cutaneous water loss (cwl) in pregnancy]. 2005548078
[ventricular rhythms in acute myocardial infarct]. 2005548111
[lues in patients previously treated with antibiotics]. 2005549229
[changes in the sialic acid content in the blood serum of calves with bronchopneumonia following treatment].the effect of a combination of calcium gluconate, magnesium sulfuricum, natrium salycilate, analgin, vit. c, vit. b1 and norsulfasol diluted in physiological solution of natrium chloride and 5% glucose was investigated. the combination was applied intravenously or per os on two groups of calves suffering from bronchopneumonia. it was established that in calves treated with the combination sialic acid is reduced as compared to calves treated only with antibiotics. therefore it is recommended to a ...1979549262
[pheochromocytoma and pregnancy (3 cases)].in this paper, a review of pregnancy and pheocromocytoma is shown. the importance of early diagnostic and adequate management is essential in this patients. when this associations exists the management must be very carefully considered to avoid high mortality risks for both, fetus and mother. 56 cases of pheocromocytoma were studied at the instituto nacional de cardiología, three of them were pregnant women which are described in this work.2005549523
immunology and pathogenesis of african animal trypanosomiasis. 1979550706
[urinary tract infections in childhood (author's transl)].the clinical symptoms of urinary tract infections (uti) are only rarely an indication of the presence of the disease in childhood. of decisive importance for the detection of uti is an appropriate investigation to determine whether there is significant bacteriuria. since in a significant proportion of cases of uti in children there is underlying congenital anomaly or functional change in the urinary tract with stasis, and since surgical means of treatment are available today, diagnosis, i.e. at ...1980551080
organization and sequence studies of the 17-piece chicken conalbumin gene.the conalbumin gene has been cloned and shown to consist of at least 17 exons approximately 60-200 base pairs long. the dna sequence upstream from the region coding for the 5' end of the mrna shows similarities with sequences present in homologous positions in other genes. high and low frequency repetitive sequences are found both upstream from the conalbumin gene and within one intron.1979551292
aspartame: assessment of developmental psychotoxicity of a new artificial sweetener. 1979551307
studies on the inhibitory effects of zinc heptanoate on microorganisms.inhibitory effect of zinc heptanoate was observed on different cultures of bacteria and fungi. growth of all the bacteria was inhibited by the compound. greatest inhibition was seen in the case of staphylococcus albus, streptococcus pyogenes, shigella dysenteriae, shigella sonnei, shigella flexneri, salmonella typhi, s. paratyphi a, s. paratyphi b, vibrio cholerae, corynebacterium diphtheriae, and e. coli whereas least inhibition was found in the case of staphylococcus aureus. in triethanolamine ...1979553835
cytotoxic activity of aeromonas hydrophila.most strains of aeromonas hydrophila tested demonstrated cytotoxic activity on several tissue-cultured cell lines. the cytotoxin is heat-labile, non-dialyzable, and immunologically distinct from that of shigella dysenteriae and clostridium perfringens. none of the aeromonas isolates was found to be enterotoxigenic by either tissue culture or rabbit ileal loop assays.1978711344
rare type of shigellosis. 1976765409
[antibacterial action by bacteriocin produced by shigella sonnei 100052]. 1975765567
[microtubular structures in the cytoplasm of macrophages and their enzymatic activity in interaction with salmonella typhi and shigella dysenteriae]. 1975765699
receptors for t2, t4 and t6 phages in sh. dysenteriae 7 and other serotypes of sh. dysenteriae.the sensitivity of four strains of sh. dysenteriae and of nine strains representing other serotypes of sh. dynsenteriae to phages t2, t4 and t6 was examined. different extracts, prepared from sensitive strains were tested for their capacity of phage inactivation. we found that the receptor substance for phage t2 is localized differently in various strains: in sh. dysenteriae 7, it was found in bacterial extracts obtained by water/phenol at 68 degrees c and in extracts obtained by trichloracetic ...1975766504
diagnostic value of indirect hemagglutination in the seroepidemiology of shigella evaluate the usefulness of the indirect hemagglutination (iha) test in the epidemiological investigation of shigellosis, single serum specimens were tested from 50 patients with shigella dysenteriae 1 (shiga bacillus) infections, 103 asymptomatic contacts of these cases, 267 adult and 100 student control, and serum specimens collected during two outbreaks caused by s. sonnei and one outbreak due to s. flexneri 6. in patients with s. dysenteriae 1, 74% demonstrated titers of greater than or eq ...1976767361
[bacteriological and epidemiological considerations on shigelloses in south vietnam (1969-1973)].during the period from 1969 to 1973, a rectal swabs from 13.943 diarrhea patients of all ages were examined by bacteriological surveys. from these specimens, 981 strains of shigella were isolated. the most commonly encounted were shigella flexneri 2. all of strains of shigella isolated were highly resistant to aureomycin, tetracyclin, terramycin, novobiocin and chloramphenicol. there has been an increase in the development of multiresistance of shigella. colimycin and streptomycin were the most ...1975770024
naturally occurring sites within the shigella dysenteriae tryptophan operon severely limit tryptophan biosynthesis.we investigated the structural, functional, and regulatory properties of the shigella dysenteriae tryptophan (trp.) operon in transduction hybrids in which the cysb-trp-region of escherichia coli is replaced by the corresponding region from s. dysenteriae. tryptophan biosynthesis was largely blocked in the hybrids, although the order of the structural genes was identical with that of e. coli. nutritional tests and enzyme assays revealed that the hybrids produced a defective anthranilate synthet ...1976770449
tryptophan operon regulation in interspecific hybrids of enteric bacteria.we examined tryptophan regulation in merodiploid hybrids in which a plasmid carrying the trp operon of escherichia was introduced into trp mutants of other enteric genera, or in which a plasmid carrying the trpr+ (repressor) gene of e. coli was transfered into fully constitutive trpr mutants of other genera. in these hybrids the trp operon of one species is controlled by the repressor of a different species. similar investigations were possible in transduction hybrids in which either the trp ope ...1976770450
resistance of shigella dysenteriae type 1 to ampicillin and other antimicrobial agents: strains isolated during a dysentery outbreak in a hospital in mexico june 1972, an epidemic of dysentery began in a hospital ward lodging 22 children with tuberculosis. fifteen of them developed the disease and five children died. the age of the children ranged from five months to four years. a rectal swab culture taken from all hospitalized children three weeks after the initiation of the outbreak revealed shigella dysenteriae type 1 in five of the patients (28%). the strains isolated were susceptible to cephalothin, gentamicin, kanamycin, colistin, trimethop ...1976772132
toxigenic escherichia coli and childhood diarrhea.stool specimens were examined from 40 children with diarrhea who were under three years of age to determine the incidence of enterotoxigenic escherichia coli in endemic diarrhea. heat-labile e. coli enterotoxin was assayed in the very sensitive and reproducible cultured adrenal tumor cell system. toxigenic e. coli were isolated from only one stool specimen and in this case infection with shigella dysenteriae was also present. none of the eight classic enteropathogenic e. coli isolates were posit ...1976775792
[immunochemical and molecular biological characteristics of dysentery phages].molecular organization of dna of six dysentery phages was studied for their classification. the pattern of glucosilation of their dna was determined by an immunochemical method and the test of competitive hybridization established the degree of homology of these dna in relation to t4 phage dna. four of the phages (ddvi, zonne "gorkyi" zonne "czechoslovakia", zonne "poland") were shown to belong to the group of t-even phages by their pattern of dna glucosilation and by their capacity to inhibit ...1976779271
a bacteriological study of the intestinal mucosa and luminal fluid of adults with acute diarrhoea.bacteriological studies of jejunal mucosal biopsy specimens and contents were performed on 22 hospitalized adult patients with acute diarrhoea and 24 control normal subjects. none of the washed homogenates of the mucosal specimens were sterile and only one fluid specimen obtained from a control subject was sterile. a definite enteric pathogen was found in only five of the 22 diarrhoea patients. there was no qualitative difference in the bacterial profile of the jejunal mucosa and contents of the ...1976779681
methylated guanine derivative as a minor base in the dna of phage ddvi shigella disenteriae.7-methylguanine has been identified in the dna of phage ddvi, which replicates in escherichia coli b cells. the amount of this minor base is 0.27 mol per 100 mol of nucleotides. in the dna of ddvi phage there is no 6-methylaminopurine which is usually a minor component in the dna of e. coli b and phage t2, yet the dna of ddvi phage is readily methylated during incubation in vitro with the b-specific methylase and adenosyl[3h]methionine with the label found only in 6-methylaminopurine. an extract ...1976779843
semisynthetic cephalosporins. synthesis and structure-activity relationships of 7-sulfonylacetamido-3-cephem-4-carboxylic acids.the synthesis and in vitro and in vivo activities of a series of 7-sulfonylacetamido-3-cephem-4-carboxylic acids with acetoxymethyl or heterocyclic thiomethyl substituents at the 3 position are described. lengthening the alkyl chain attached to the sulfonyl group increased gram-positive activity but the effect on gram-negative activity was variable. other structural changes on the 7-acyl side chain resulted in only minor changes in vitro activity. the protective effectiveness in infected mice g ...1976781242
[grigor'ev-shiga dysentery and the current trends in its spread]. 1976782107
intraventricular antipyretics and bacterial pyrogen adult fowls with cannulae chronically implanted into the iiird cerebral ventricle or into the hypothalamus, the effects of various hydrosoluble antipyretics, given intraventricularly, on bacterial pyrogen fever were studied. it has been shown that fever evoked by intrahypothalamic or intraventricular infusion of o somatic antigen of shigella dysenteriae was reduced by intraventricular administration of acetylsalicylate-lysine, indomethacin-methylglucamine or ibuprofen-lysine given during the ...1976782392
shigella dysenteriae i: a forgotten cause of pseudomembranous colitis. 1976784931
inhibition of in vitro protein synthesis by shigella dysenteriae 1 toxin. 1976786292
effect of enterotoxins of vibrio cholerae, escherichia coli, and shigella dysenteriae type 1 on fluid and electrolyte transport in the colon.experiments were designed to determine whether the enterotoxins of vibrio cholerae, escherichia coli, and shigella dysenteriae type 1 alter the movement of fluid and electrolytes in the rat cecum. net secretion of water and sodium were observed after incubation of 1.67 x10(-5) mug of purified cholera toxin (choleragen)/ml for 18 hr or of 50 mug/ml for 3 hr. the effect of choleragen on cecal transport of water and electrolytes was related to the dose. in addition, choleragen increased cecal mucos ...1976787442
the problem of bacterial diarrhoea.the reported incidence of "pathogenic" bacteria, as judged by serotype, in the stools of children with acute diarrhoea has varied from 4 to 33% over the last twenty years. techniques such as tissue culture provide a means for detecting enterotoxin-producing strains of bacteria, strains which often do not possess "pathogenic" serotypes. "pathogenicity" requires redefinition, and the aetiological importance of bacteria in diarrhoea is probably considerably greater than previous reports have indica ...1976791597
[effect of gram-negative bacterial polysaccharides on various immunity reactions and experimental tumors]. 1976794646
resistance to antibiotics of shigella strains isolated in somalia.the resistance to antibiotics of 240 shigella strains isolated in somalia from 1973 to 1976 was studied. many strains, particularly those of shigella dysenteriae type 1, were found to be resistant to more than one drug. in view of their resistance to ampicillin, chloramphenicol, streptomycin, tetracycline, and sulfonamides, it is suggested that polymyxin b or m sulfate - which have proved to be effective in vivo - should be used for the treatment of clinically typical cases of bacillary dysenter ...1976799953
the destruction of tumor cells by alloimmune peritoneal cells: mechanism of action of activated macrophages in vitro. 1975804549
microbial development of drug resistance: mechanisms and clinical significance.bacteria have demonstrated a disconcerting ability to develop resistance to antimicrobial agents nearly as quickly as new compounds become available. during the past two decades the molecular bases of several types of resistance have been elucidated. mechanisms of resistance include the transference of genetic material either through conjugation (involving direct contact between microorganisms), or indirectly through transduction (involving bacteriophages). in addition to this "infectious" drug ...1975806419
conditions critical for optimal visualization of bacteriophage adsorbed to bacterial surfaces by scanning electron microscopy.the potential of scanning electron microscopy as a tool for the detection of viruses on cell surfaces has been studied using bacteriophage p1 adsorbed to shigella dysenteriae as a model system. viral particles were readily detectable by scanning electron microscopy on the surface of infected cells which were fixed with glutaraldehyde followed by postfixation in oso4 and prepared by critical point drying. the virus-studded surface of the infected cells differed markedly from the relatively smooth ...1975806704
the influence of some cations on bacterial endotoxins: the course of its isolation and purification, bacterial endotoxin may be contaminated by some inorganic cations. the present study was concerned with cu-2+ contamination of the lipopolysaccharide-protein complex (lps) extracted from shigella dysenteriae 1 s and r strains. the cu-2+ contamination level of lps prepared by raynaud's method and partly purified through sephadex g200 and sepharose 4b was in the range of 1-5 mug cu-2+/mg lps. crude raynauds extract, similarly as lps prepared by west ...1975808051
cell-wall lipopolysaccharide of the 'shigella-like' escherichia coli 0124. structure of the polysaccharide chain.from escherichia coli 0124 two lipopolysaccharide preparations were obtained with phenol/water extraction and cetavlon precipitation. polyacrylamide gel electrophoresis in the presence of sodium dodecylsulfate and chemical analysis showed that the two preparations from e. coli 0124 and the corresponding preparations from shigella dysenteriae type 3 reacted alike. the o-specific polysaccharide moiety was characterized with proton magnetic resonance spectroscopy, optical rotation and paper electro ...1976819266
inhibition of adp-induced platelet aggregation as a possible test for evaluation of the enterotoxigenicity of some enterobacteria. preliminary study].some culture filtrates or enterotoxin preparations from enterobacteria that activate the adenylate cyclase system (vibrio cholerae, lt fraction from escherichia coli and klebsiella pneumoniae, shigella dysenteriae type 1) exibit an inhibiting effect on adp-induced platelet aggregation, while other enterotoxin preparations not effective on adenylate cyclase system, don't interfere with this model. the a. propose the platelet aggregation as cellular assay to detect enterotoxin fractions effective ...19761028645
studies on shigella isolated in southern taiwan.during 1969, a total of 1,476 fecal and rectal swab specimens was collected from children with diarrhea and 249 strains of shigella were isolated. the incidence was 16.9%. the serotypes of 249 strains were: shigella dysenteriae, 1.6% (4 strains); s. flexneri, 73.1% (182 strains); s. boydii, 3.2 (8 strains) and s. sonnei, 22.1% (55 strains). there was no marked difference of the isolation rate throughout the whole year. the susceptibility of shigella isolates to chemotherapeutic agents were also ...19761036983
presence of messenger specifying sequences in the dna of chromatin subunits.messenger-specifying sequences in subunits of human lymphocyte chromatin were detected by hybridization of dna complementary to cytoplasmic polyadenylylated rna with dna isolated from the subunits. comparison of the kinetics and extents of hybridization of complementary dna with chromatin subunit dna and with nuclear dna showed that most of the repetitive sequences and single copy sequences in mrna are present in chromatin subunits. this result indicates that inclusion of a dna sequence into the ...19761064026
[the sjögren-gougerot syndrome].the sjögren-gougerot syndrome represents a rare disease of the collagenous tissue characterized by the three symptoms xerophtalmy, xerostomy, polyarthritis. women after the menopause are the most affected. oral symptoms addup to diverse dermatological manifestations. the bilateral parotidic swelling and systemic complications accompany the disease, and the immunological disorder is coupled with hypergammaglobulinemia. prognosis is very reserved and treatment delicate.20051064976
letter: microvilli. 20051065167
[dynamical study of cerebrospinal fluid at the spinal level during isotopic cisternography. 74 cases].physiology teaches that in addition ot be basic areas of c.s.f. resorption in the region of the cerebrum, supplementary zones exist situated in particular at the coverings of the spinal nerves. the aim of this study was a quantitative and dynamic analysis of spinal flow in 74 subjects, 64 of whom had clinical signs of communicating hydrocephalus. in certain of them, classical examinations provided no precise indications as to the appropriate neurosurgical procedure. study of the dynamics and res ...20051068623
location. 20051070368
once daily dosage beta-blockade: antihypertensive efficacy of slow release oxprenolol as related to renin and age.a single daily dose antihypertensive therapy with a new slow-release (sr) form of the beta-adrenoceptor blocking agent oxprenolol was as effective as a standard tid beta-blocker regimen in maintaining therapeutic effects over 24 hours. the good overall response rate (target larger than or equal to mmhg diastolic) of 67% was achieved in eight of the 11 high renin patients and 16 out of the 20 normal renin ones; the five low renin patients, who were also older, proved to be non-responsive. in term ...20011071402
[use of the tine test in the diagnosis of tuberculosis infection]. 20051081245
[use of pitressin in the management of gastrointestinal bleeding. report of a case]. 20051081398
effect of levamisole on e-rosette-forming cells in vivo and in vitro in hodgkin's disease.incubation in vitro of lymphocytes from patients with hodgkin's disease with 40 mug per milliliter of levamisole resulted in a rise in the number of e-rosette-forming cells from 33.6 +/- 12.5 per cent (mean +/- s.d.) to 56.7 +/- 14.6 per cent. the drug had no effect on normal lymphocytes. ten patients with hodgkin's disease treated six months previously with levamisole were restudied. the positive skin tests to ppd, candida and mumps persisted. however, the e-rosette-forming cells decreased to t ...20051082545
emergency arteriography in acute gastrointestinal bleeding.emergency arteriography was carried out on 35 patients with acute gastrointestinal bleeding, in 31 of them within two hours of active bleeding (a haematemisis; a diagnostic change in central venous pressure, pulse rate, or blood pressure; or gastric aspiration of fresh blood). a definite site of bleeding was identified in 27 patients (77%)-this being a small-intestinal vascular abnormality in three--and a probable site in three. confirmation of the bleeding site was obtained in 20 out of 23 pati ...20001083756
the lymphocyte inhibiting factor extracted from the thymus (lift): inhibition of the dna synthesis in vitro. 20001083769
the effector cells in human peripheral blood mediating mitogen-induced cellular cytotoxicity and antibody-dependent cellular cytotoxicity.the identity of the effector cells in human peripheral blood capable of mediating mitogen-induced cellular cytotoxicity (micc) and antibody-dependent cellular cytotoxicity (adcc) was investigated utilizing effector cell populations consisting of purified polymorphonuclear leukocytes, macrophages, lymphocytes, and cell surface immunoglobulin (sig)-negative and sig-positive lymphocyte subpopulations obtained by sephadex anti-fab immunoabsorbent column fractionation techniques. chicken erythrocytes ...19761087314
[role of lymphocytes in physiological and pathological processes]. 20051087411
somatic antigen of shigella dysenteriae type 3. structural features of specific polysaccharide chain.on mild acid hydrolysis of lipolysaccharide from shigella dysenteriae type 3 the o-specific polysaccharide (hapten) was obtained which appeared to be acidic branched hexosaminoglycan. the repeating unit of this polysaccharide represents a pentasaccharide composed of two d-galactose residues, n-acetyl-d-galactosamine, d-glucose and unidentified acidic component. on the basis of methylation analysis, periodate oxidation, partial acid hydrolysis and chromic anhydride oxidation it is concluded that ...19751089541
antimicrobial resistance of shigellae isolated in michigan.patterns of antimicrobial resistance were studied for 213 strains of shigellae isolated in rural and urban areas of michigan by quantitative techniques: 66% of these organisms were resistant to ampicillin, tetracycline, cephalexin, or chloramphenicol or had multiple resistance to various combinations of these antibiotics. the incidence of resistant organisms was higher in the detroit-wayne county area, which is the most urban part of the state. nalidixic acid and oxolinic acid were noted to be q ...19751089819
observations on the serologic changes in the recombinants in shigella flexneri serotype 4a.studies on the antigenic composition of 84 diagnostic strains of s. flexneri serotype 4a and their lac+ recombinants from a cross with e. coli hfrc were carried out. considerable differentiation of agglutination reaction was found both in original material and in recombinants. an interesting group included recombinants which completely lost their capability to agglutinate with sera specific for type and group antigens and preserved only the capability to agglutinate in the polyvalent serum of s. ...19751090112
comparison of secretory and histological effects of shigella and cholera enterotoxins in rabbit jejunum.the purpose of this study was to compare the actions of shigella toxin and cholera toxin to determine if mucosal damage is a prerequisite for shigella toxin-induced secretion. the secretory response to maximal doses of cholera toxin and shigella toxin were compared. the maximal rate of secretion and the electrolyte and protein concentration of the intestinal fluid were similar for both toxins. on the other hand, the time of onset after exposure to the toxin was 105 min for shigella toxin and 15 ...19751090481
occurrence of the bacteriophage lambda receptor in some escherichia coli k-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. lambda receptor activity was found in extracts from all wild strains of e. coli tested, although most of them fail to support growth of the phage. in some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. in other cases, adsorption does occur, and the nature of the block in ...19751090748
shiga bacillus dysentery associated with marked leukocytosis and erythrocyte fragmentation.granulocytic leukemoid reactions (white blood cell counts greater than 50,000 with myelocytes and promyelocytes in the peripheral blood) were documented in 15 per cent of 273 patients with dysentery due to shigella dysenteriae, type 1 (shiga bacillus) in bangladesh. peak granulocytosis occurred during the second week of illness, when the children were commonly afebrile and diarrhea had ceased or was subsiding. more than half of the patients with leukemoid reactions subsequently developed a fall ...19751090770
production and characterization of exotoxin(s) of shigella dysenteriae type 1.a semicontinuous fermenter system was developed in which broth culture filtrates of shigella dysenteriae type 1 yielded substantial amounts of exotoxin. biologic activity of the exotoxin was characterized by means of three assays: the rabbit ileal loop for fluid evocation (enterotoxicity), mouse lethality after parenteral injection (neurotoxicity), and hela cell toxicity in vitro (cytotoxicity). although the culture filtrate was highly active, disc electrophoresis revealed that the toxin is a mi ...19751092769
superiority of macconkey's agar over salmonella-shigella agar for isolation of shigella dysenteriae type 1.the efficiency of macconkey's agar in the isolation of various types of shigella was compared with that of salmonella-shigella (ss) agar during an extensive 18-month outbreak of disease caused by shigella. in all, 1,580 isolates of shigella were obtained from 12,307 rectal swab and fecal samples of patients with diarrhea and their contacts by direct plating onto macconkey's and ss agars. shigella dysenteriae type 1 and shigella flexneri constituted 55 percent and 33 percent of all isolates, resp ...19751094073
letter: hemolytic uremic syndrome after shigellosis. 19751094293
proceedings: dissociation of bacterial pyrexia from prostaglandin e activity. 19751097014
selective cleavage of glycosidic linkages: studies with the o-specific polysaccharide from shigella dysenteriae type 3.treatment of the o-specific polysaccharide from shigella dysenteriae type 3 with hydrazine in the presence of hydrazine sulphate resulted in quantitative n-deacetylation with the formation of a modified polysaccharide containing free amino groups. oxidation of the modified polysaccharide with periodate did not destroy the 2-amino-2-deoxygalactose residues, thus indicating that they were substituted at position 3. acid hydrolysis of the modified polysaccharide afforded 3-o-(2-amino-2-deoxy-beta ...19751097111
shigella strains associated with infantile diarrhea in the kaohsiung 1969 and 1974, 375 shigella strains were isolated in the kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. in 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. the isolation rates were higher in may (21.2%), october (20.8%), april (20.6%), august (19.7), november (18.8%) and january (18.5%), than in o ...19751097211
[antigenic relationships between "levinea amalonatica" and "shigella dysenteriae" and "boydii" (author's transl)].twenty-eight strains among thirty-five levinea amalonatica show o antigenic relationships with shigella as follows: with s. dysenteriae 3 (5 strains), s. dysenteriae 4 (1 strain), s. dysenteriae 5 (3 strains), s. dysenteriae 7 (11 strains), s. boydii 6 (7 strains), and with both s. boydii 15 and s. dysenteriae 8 (1 strain). these strains do not induce purulent keratogenous conjunctivitis in guinea pigs as shigella do.19751098541
an outbreak of dysentery caused by shigella dysenteriae type 1 on a coral island in the bay of epidemic of severe dysentery occurred on st. martin island in the bay of bengal at a time when the island, with a population of 1,318, was isolated from the mainland because of the monsoon season. there were 434 cases and 28 deaths within a three-month period. mortality (2%) was limited to the very young and the elderly. shigella dysenteriae type 1 (shiga bacillus) was isolated from 12 of 65 rectal swab specimens. all strains gave similar biochemical reactions and were resistant to tetracycli ...19751099145
epidemiologic investigation of an outbreak of shiga bacillus dysentery in an island epidemic of dysentery broke out in st. martin island during may through july 1973. the epidemic was caused by shigella dysenteriae type 1. the dysentery could not be controlled by conventional antibiotics and other antidysenteric drugs. the average attack rate was 32.9%. the age specific attack rate was highest in the age group 1-4 years (52.2%). the attack rates were higher in smaller families. the rates were not greatly different amongst people using different sources of water. the overall ...19751101385
some immunochemical and chemical aspects of s and r shigella dysenteriae 1 endotoxins.endotoxins of s and r forms of shigella dysenteriae 1 were prepared by nacl-na citrate extraction, purified by gel chromatography on sephadex g 200 and on sepharose 4b and subjected to immunochemical and chemical analysis. the toxins contained 25--30% of lipids, 40--50% of carbohydrates and 14--24% of protein. the lipid and protein moieties of the lipopolysaccharide-protein complexes exhibited no significant difference, whereas the sugar moieties differed markedly (both qualitatively and quantit ...19751102598
superinfection immunity and prophage repression in phage p1. ii. mapping of the immunity-difference and ampicillin-resistance loci of p1 and phi amp. 19751103441
selective cleavage of glycosidic linkages: studies with the polysaccharide component of shigella dysenteriae type 6 lipopolysaccharide.the polysaccharide component obtained from the lipopolysaccharide of shigella dysenteriae type 6 was subjected to milk hydrolysis with acid, and the products were fractionated on sephadex g-50. an acidic hexosaminoglycan and a core oligosaccharide fraction were obtained, the former containing d-glucose, d-galactose, 2-acetamido-2-deoxy-d-galactose (in the ratios 1:1:1), and an unidentified acidic component (x). the hexosaminoglycan was n-deacetylated and then hydrolysed and deaminated to give 3- ...19751104165
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